Amino acid dipepetide frequency for Bat mastadenovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.549AlaAla: 7.549 ± 1.077
1.49AlaCys: 1.49 ± 0.406
3.973AlaAsp: 3.973 ± 0.503
4.47AlaGlu: 4.47 ± 0.776
4.172AlaPhe: 4.172 ± 0.518
4.569AlaGly: 4.569 ± 0.715
2.384AlaHis: 2.384 ± 0.397
3.973AlaIle: 3.973 ± 0.578
3.973AlaLys: 3.973 ± 0.805
7.251AlaLeu: 7.251 ± 1.187
1.887AlaMet: 1.887 ± 0.551
3.576AlaAsn: 3.576 ± 0.637
4.569AlaPro: 4.569 ± 0.776
3.476AlaGln: 3.476 ± 0.51
3.377AlaArg: 3.377 ± 0.882
3.576AlaSer: 3.576 ± 0.568
3.774AlaThr: 3.774 ± 0.5
6.257AlaVal: 6.257 ± 0.585
0.795AlaTrp: 0.795 ± 0.242
2.284AlaTyr: 2.284 ± 0.429
0.0AlaXaa: 0.0 ± 0.0
Cys
1.689CysAla: 1.689 ± 0.39
1.49CysCys: 1.49 ± 0.517
0.894CysAsp: 0.894 ± 0.294
1.093CysGlu: 1.093 ± 0.31
0.795CysPhe: 0.795 ± 0.25
1.391CysGly: 1.391 ± 0.481
0.298CysHis: 0.298 ± 0.171
0.695CysIle: 0.695 ± 0.261
0.199CysLys: 0.199 ± 0.126
2.682CysLeu: 2.682 ± 0.548
0.695CysMet: 0.695 ± 0.249
0.993CysAsn: 0.993 ± 0.304
0.397CysPro: 0.397 ± 0.175
0.497CysGln: 0.497 ± 0.228
0.795CysArg: 0.795 ± 0.3
0.993CysSer: 0.993 ± 0.273
1.788CysThr: 1.788 ± 0.477
1.192CysVal: 1.192 ± 0.341
0.199CysTrp: 0.199 ± 0.113
1.093CysTyr: 1.093 ± 0.365
0.0CysXaa: 0.0 ± 0.0
Asp
2.88AspAla: 2.88 ± 0.526
1.192AspCys: 1.192 ± 0.35
3.079AspAsp: 3.079 ± 0.586
3.079AspGlu: 3.079 ± 0.625
1.986AspPhe: 1.986 ± 0.43
1.986AspGly: 1.986 ± 0.43
1.291AspHis: 1.291 ± 0.355
2.781AspIle: 2.781 ± 0.534
1.689AspLys: 1.689 ± 0.387
5.264AspLeu: 5.264 ± 0.621
1.291AspMet: 1.291 ± 0.343
3.278AspAsn: 3.278 ± 0.455
3.377AspPro: 3.377 ± 0.584
1.391AspGln: 1.391 ± 0.242
2.384AspArg: 2.384 ± 0.592
3.675AspSer: 3.675 ± 0.593
2.88AspThr: 2.88 ± 0.549
2.88AspVal: 2.88 ± 0.577
0.695AspTrp: 0.695 ± 0.223
1.291AspTyr: 1.291 ± 0.305
0.0AspXaa: 0.0 ± 0.0
Glu
4.966GluAla: 4.966 ± 0.835
0.795GluCys: 0.795 ± 0.31
3.079GluAsp: 3.079 ± 0.634
6.257GluGlu: 6.257 ± 1.186
1.986GluPhe: 1.986 ± 0.314
4.172GluGly: 4.172 ± 0.737
0.497GluHis: 0.497 ± 0.198
2.98GluIle: 2.98 ± 0.47
2.781GluLys: 2.781 ± 1.003
4.37GluLeu: 4.37 ± 0.711
1.788GluMet: 1.788 ± 0.471
3.774GluAsn: 3.774 ± 0.622
4.072GluPro: 4.072 ± 0.661
1.689GluGln: 1.689 ± 0.433
2.98GluArg: 2.98 ± 0.608
2.582GluSer: 2.582 ± 0.585
4.072GluThr: 4.072 ± 0.649
4.37GluVal: 4.37 ± 0.693
0.596GluTrp: 0.596 ± 0.243
1.291GluTyr: 1.291 ± 0.343
0.0GluXaa: 0.0 ± 0.0
Phe
2.284PheAla: 2.284 ± 0.528
0.795PheCys: 0.795 ± 0.307
2.284PheAsp: 2.284 ± 0.527
2.483PheGlu: 2.483 ± 0.558
1.589PhePhe: 1.589 ± 0.462
1.291PheGly: 1.291 ± 0.338
1.093PheHis: 1.093 ± 0.343
2.582PheIle: 2.582 ± 0.394
1.788PheLys: 1.788 ± 0.433
4.37PheLeu: 4.37 ± 0.789
1.391PheMet: 1.391 ± 0.348
1.887PheAsn: 1.887 ± 0.326
2.284PhePro: 2.284 ± 0.365
1.49PheGln: 1.49 ± 0.391
2.582PheArg: 2.582 ± 0.501
3.377PheSer: 3.377 ± 0.611
2.682PheThr: 2.682 ± 0.439
3.278PheVal: 3.278 ± 0.535
0.199PheTrp: 0.199 ± 0.141
1.986PheTyr: 1.986 ± 0.407
0.0PheXaa: 0.0 ± 0.0
Gly
4.867GlyAla: 4.867 ± 0.59
0.894GlyCys: 0.894 ± 0.285
1.887GlyAsp: 1.887 ± 0.365
3.377GlyGlu: 3.377 ± 0.583
2.185GlyPhe: 2.185 ± 0.469
4.966GlyGly: 4.966 ± 0.715
1.093GlyHis: 1.093 ± 0.416
2.582GlyIle: 2.582 ± 0.471
1.788GlyLys: 1.788 ± 0.551
5.662GlyLeu: 5.662 ± 0.935
1.391GlyMet: 1.391 ± 0.351
3.178GlyAsn: 3.178 ± 0.698
2.682GlyPro: 2.682 ± 0.451
2.781GlyGln: 2.781 ± 0.518
4.172GlyArg: 4.172 ± 0.556
3.576GlySer: 3.576 ± 0.503
3.874GlyThr: 3.874 ± 0.641
3.774GlyVal: 3.774 ± 0.546
0.795GlyTrp: 0.795 ± 0.211
1.391GlyTyr: 1.391 ± 0.301
0.0GlyXaa: 0.0 ± 0.0
His
1.291HisAla: 1.291 ± 0.339
0.695HisCys: 0.695 ± 0.353
0.497HisAsp: 0.497 ± 0.253
0.298HisGlu: 0.298 ± 0.176
0.894HisPhe: 0.894 ± 0.319
1.093HisGly: 1.093 ± 0.276
0.596HisHis: 0.596 ± 0.217
1.192HisIle: 1.192 ± 0.297
1.291HisLys: 1.291 ± 0.322
2.384HisLeu: 2.384 ± 0.495
0.695HisMet: 0.695 ± 0.23
0.795HisAsn: 0.795 ± 0.22
1.589HisPro: 1.589 ± 0.423
0.894HisGln: 0.894 ± 0.336
1.391HisArg: 1.391 ± 0.367
1.49HisSer: 1.49 ± 0.366
1.093HisThr: 1.093 ± 0.306
1.192HisVal: 1.192 ± 0.345
0.497HisTrp: 0.497 ± 0.227
1.093HisTyr: 1.093 ± 0.363
0.0HisXaa: 0.0 ± 0.0
Ile
3.377IleAla: 3.377 ± 0.618
0.695IleCys: 0.695 ± 0.235
2.086IleAsp: 2.086 ± 0.351
2.582IleGlu: 2.582 ± 0.525
1.49IlePhe: 1.49 ± 0.402
2.88IleGly: 2.88 ± 0.45
0.695IleHis: 0.695 ± 0.254
2.781IleIle: 2.781 ± 0.441
3.675IleLys: 3.675 ± 0.587
3.476IleLeu: 3.476 ± 0.591
0.795IleMet: 0.795 ± 0.264
2.483IleAsn: 2.483 ± 0.369
3.476IlePro: 3.476 ± 0.491
2.086IleGln: 2.086 ± 0.503
2.483IleArg: 2.483 ± 0.471
3.874IleSer: 3.874 ± 0.699
3.774IleThr: 3.774 ± 0.591
2.98IleVal: 2.98 ± 0.427
0.497IleTrp: 0.497 ± 0.204
0.596IleTyr: 0.596 ± 0.246
0.0IleXaa: 0.0 ± 0.0
Lys
2.781LysAla: 2.781 ± 0.65
0.993LysCys: 0.993 ± 0.466
2.384LysAsp: 2.384 ± 0.36
2.086LysGlu: 2.086 ± 0.47
2.086LysPhe: 2.086 ± 0.396
2.582LysGly: 2.582 ± 0.691
0.795LysHis: 0.795 ± 0.279
3.377LysIle: 3.377 ± 0.622
3.079LysLys: 3.079 ± 0.6
4.867LysLeu: 4.867 ± 0.766
1.093LysMet: 1.093 ± 0.361
2.086LysAsn: 2.086 ± 0.341
2.086LysPro: 2.086 ± 0.398
1.689LysGln: 1.689 ± 0.324
3.079LysArg: 3.079 ± 0.897
2.88LysSer: 2.88 ± 0.707
3.377LysThr: 3.377 ± 0.503
2.98LysVal: 2.98 ± 0.516
0.497LysTrp: 0.497 ± 0.182
1.689LysTyr: 1.689 ± 0.304
0.0LysXaa: 0.0 ± 0.0
Leu
7.151LeuAla: 7.151 ± 0.663
2.086LeuCys: 2.086 ± 0.534
5.264LeuAsp: 5.264 ± 0.586
4.867LeuGlu: 4.867 ± 0.665
2.781LeuPhe: 2.781 ± 0.525
4.966LeuGly: 4.966 ± 0.764
2.88LeuHis: 2.88 ± 0.51
3.476LeuIle: 3.476 ± 0.39
5.761LeuLys: 5.761 ± 0.773
7.946LeuLeu: 7.946 ± 0.907
1.589LeuMet: 1.589 ± 0.416
4.569LeuAsn: 4.569 ± 0.864
6.953LeuPro: 6.953 ± 0.715
4.271LeuGln: 4.271 ± 0.93
5.86LeuArg: 5.86 ± 0.803
6.853LeuSer: 6.853 ± 0.952
6.953LeuThr: 6.953 ± 1.13
5.066LeuVal: 5.066 ± 0.828
0.993LeuTrp: 0.993 ± 0.207
3.576LeuTyr: 3.576 ± 0.617
0.0LeuXaa: 0.0 ± 0.0
Met
2.483MetAla: 2.483 ± 0.501
0.397MetCys: 0.397 ± 0.228
1.589MetAsp: 1.589 ± 0.296
2.483MetGlu: 2.483 ± 0.502
1.391MetPhe: 1.391 ± 0.415
1.291MetGly: 1.291 ± 0.365
0.397MetHis: 0.397 ± 0.254
1.192MetIle: 1.192 ± 0.44
0.596MetLys: 0.596 ± 0.241
2.682MetLeu: 2.682 ± 0.361
0.497MetMet: 0.497 ± 0.207
1.093MetAsn: 1.093 ± 0.289
1.391MetPro: 1.391 ± 0.376
1.391MetGln: 1.391 ± 0.319
1.192MetArg: 1.192 ± 0.431
1.788MetSer: 1.788 ± 0.358
0.497MetThr: 0.497 ± 0.263
0.695MetVal: 0.695 ± 0.284
0.298MetTrp: 0.298 ± 0.146
1.391MetTyr: 1.391 ± 0.346
0.0MetXaa: 0.0 ± 0.0
Asn
3.576AsnAla: 3.576 ± 0.512
0.795AsnCys: 0.795 ± 0.276
2.284AsnAsp: 2.284 ± 0.429
2.483AsnGlu: 2.483 ± 0.472
2.682AsnPhe: 2.682 ± 0.463
3.774AsnGly: 3.774 ± 0.751
0.397AsnHis: 0.397 ± 0.207
2.98AsnIle: 2.98 ± 0.537
1.788AsnLys: 1.788 ± 0.289
4.569AsnLeu: 4.569 ± 0.777
1.093AsnMet: 1.093 ± 0.319
2.88AsnAsn: 2.88 ± 0.757
3.973AsnPro: 3.973 ± 0.499
1.986AsnGln: 1.986 ± 0.479
2.682AsnArg: 2.682 ± 0.514
3.576AsnSer: 3.576 ± 0.542
2.98AsnThr: 2.98 ± 0.557
3.178AsnVal: 3.178 ± 0.608
0.894AsnTrp: 0.894 ± 0.237
2.582AsnTyr: 2.582 ± 0.599
0.0AsnXaa: 0.0 ± 0.0
Pro
6.456ProAla: 6.456 ± 0.886
1.192ProCys: 1.192 ± 0.478
2.682ProAsp: 2.682 ± 0.47
3.178ProGlu: 3.178 ± 0.378
2.086ProPhe: 2.086 ± 0.573
2.284ProGly: 2.284 ± 0.534
0.993ProHis: 0.993 ± 0.173
2.086ProIle: 2.086 ± 0.472
2.284ProLys: 2.284 ± 0.628
5.761ProLeu: 5.761 ± 0.761
1.291ProMet: 1.291 ± 0.353
2.384ProAsn: 2.384 ± 0.398
6.357ProPro: 6.357 ± 1.027
2.781ProGln: 2.781 ± 0.478
4.271ProArg: 4.271 ± 0.595
5.562ProSer: 5.562 ± 0.844
4.072ProThr: 4.072 ± 0.645
4.867ProVal: 4.867 ± 0.865
0.497ProTrp: 0.497 ± 0.23
2.284ProTyr: 2.284 ± 0.459
0.0ProXaa: 0.0 ± 0.0
Gln
3.576GlnAla: 3.576 ± 0.495
0.795GlnCys: 0.795 ± 0.257
1.689GlnAsp: 1.689 ± 0.289
3.476GlnGlu: 3.476 ± 0.469
1.391GlnPhe: 1.391 ± 0.443
2.582GlnGly: 2.582 ± 0.417
0.695GlnHis: 0.695 ± 0.242
1.391GlnIle: 1.391 ± 0.381
2.284GlnLys: 2.284 ± 0.657
4.47GlnLeu: 4.47 ± 0.755
1.291GlnMet: 1.291 ± 0.345
2.483GlnAsn: 2.483 ± 0.549
2.086GlnPro: 2.086 ± 0.472
2.781GlnGln: 2.781 ± 0.484
2.781GlnArg: 2.781 ± 0.688
3.278GlnSer: 3.278 ± 0.5
2.582GlnThr: 2.582 ± 0.371
2.88GlnVal: 2.88 ± 0.426
0.397GlnTrp: 0.397 ± 0.206
1.093GlnTyr: 1.093 ± 0.369
0.0GlnXaa: 0.0 ± 0.0
Arg
6.357ArgAla: 6.357 ± 0.904
0.993ArgCys: 0.993 ± 0.284
2.88ArgAsp: 2.88 ± 0.489
3.178ArgGlu: 3.178 ± 0.646
1.689ArgPhe: 1.689 ± 0.342
4.072ArgGly: 4.072 ± 0.593
1.589ArgHis: 1.589 ± 0.407
1.49ArgIle: 1.49 ± 0.402
2.582ArgLys: 2.582 ± 0.496
4.966ArgLeu: 4.966 ± 0.845
1.391ArgMet: 1.391 ± 0.319
2.98ArgAsn: 2.98 ± 0.464
3.178ArgPro: 3.178 ± 0.79
2.086ArgGln: 2.086 ± 0.456
6.853ArgArg: 6.853 ± 1.705
3.774ArgSer: 3.774 ± 0.664
1.986ArgThr: 1.986 ± 0.527
3.476ArgVal: 3.476 ± 0.792
1.49ArgTrp: 1.49 ± 0.303
1.788ArgTyr: 1.788 ± 0.656
0.0ArgXaa: 0.0 ± 0.0
Ser
5.165SerAla: 5.165 ± 0.602
1.291SerCys: 1.291 ± 0.325
2.98SerAsp: 2.98 ± 0.491
3.973SerGlu: 3.973 ± 0.668
4.072SerPhe: 4.072 ± 0.548
4.271SerGly: 4.271 ± 0.56
1.291SerHis: 1.291 ± 0.269
3.675SerIle: 3.675 ± 0.688
2.88SerLys: 2.88 ± 0.614
6.257SerLeu: 6.257 ± 0.765
1.589SerMet: 1.589 ± 0.421
3.377SerAsn: 3.377 ± 0.551
4.569SerPro: 4.569 ± 0.904
3.178SerGln: 3.178 ± 0.557
4.172SerArg: 4.172 ± 0.926
6.655SerSer: 6.655 ± 1.141
3.377SerThr: 3.377 ± 0.461
4.37SerVal: 4.37 ± 0.619
0.894SerTrp: 0.894 ± 0.309
2.88SerTyr: 2.88 ± 0.398
0.0SerXaa: 0.0 ± 0.0
Thr
4.569ThrAla: 4.569 ± 0.562
1.093ThrCys: 1.093 ± 0.321
2.781ThrAsp: 2.781 ± 0.441
2.98ThrGlu: 2.98 ± 0.497
2.98ThrPhe: 2.98 ± 0.432
3.377ThrGly: 3.377 ± 0.543
1.689ThrHis: 1.689 ± 0.339
3.874ThrIle: 3.874 ± 0.546
2.185ThrLys: 2.185 ± 0.481
7.251ThrLeu: 7.251 ± 0.958
0.993ThrMet: 0.993 ± 0.25
2.781ThrAsn: 2.781 ± 0.458
4.072ThrPro: 4.072 ± 0.54
3.377ThrGln: 3.377 ± 0.744
2.384ThrArg: 2.384 ± 0.45
4.072ThrSer: 4.072 ± 0.592
3.675ThrThr: 3.675 ± 0.628
5.165ThrVal: 5.165 ± 0.551
1.093ThrTrp: 1.093 ± 0.381
2.384ThrTyr: 2.384 ± 0.646
0.0ThrXaa: 0.0 ± 0.0
Val
4.37ValAla: 4.37 ± 0.536
0.894ValCys: 0.894 ± 0.334
2.98ValAsp: 2.98 ± 0.731
4.271ValGlu: 4.271 ± 0.731
3.079ValPhe: 3.079 ± 0.735
2.98ValGly: 2.98 ± 0.451
0.596ValHis: 0.596 ± 0.198
2.284ValIle: 2.284 ± 0.33
2.781ValLys: 2.781 ± 0.644
4.966ValLeu: 4.966 ± 0.75
1.986ValMet: 1.986 ± 0.429
4.172ValAsn: 4.172 ± 0.77
3.973ValPro: 3.973 ± 0.766
3.476ValGln: 3.476 ± 0.578
3.675ValArg: 3.675 ± 0.665
4.966ValSer: 4.966 ± 0.681
5.761ValThr: 5.761 ± 0.627
4.668ValVal: 4.668 ± 0.704
0.596ValTrp: 0.596 ± 0.191
3.079ValTyr: 3.079 ± 0.558
0.0ValXaa: 0.0 ± 0.0
Trp
0.695TrpAla: 0.695 ± 0.231
0.099TrpCys: 0.099 ± 0.092
0.795TrpAsp: 0.795 ± 0.211
0.596TrpGlu: 0.596 ± 0.248
0.497TrpPhe: 0.497 ± 0.239
1.391TrpGly: 1.391 ± 0.369
0.298TrpHis: 0.298 ± 0.159
0.298TrpIle: 0.298 ± 0.153
0.795TrpLys: 0.795 ± 0.314
1.291TrpLeu: 1.291 ± 0.297
0.397TrpMet: 0.397 ± 0.179
0.695TrpAsn: 0.695 ± 0.262
0.795TrpPro: 0.795 ± 0.259
0.497TrpGln: 0.497 ± 0.254
0.497TrpArg: 0.497 ± 0.174
1.291TrpSer: 1.291 ± 0.445
0.795TrpThr: 0.795 ± 0.197
0.199TrpVal: 0.199 ± 0.126
0.099TrpTrp: 0.099 ± 0.084
0.298TrpTyr: 0.298 ± 0.22
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.291TyrAla: 1.291 ± 0.287
1.192TyrCys: 1.192 ± 0.267
2.284TyrAsp: 2.284 ± 0.512
1.887TyrGlu: 1.887 ± 0.4
1.887TyrPhe: 1.887 ± 0.394
0.993TyrGly: 0.993 ± 0.234
1.391TyrHis: 1.391 ± 0.44
1.093TyrIle: 1.093 ± 0.238
2.284TyrLys: 2.284 ± 0.506
3.377TyrLeu: 3.377 ± 0.546
1.49TyrMet: 1.49 ± 0.387
1.689TyrAsn: 1.689 ± 0.404
1.49TyrPro: 1.49 ± 0.296
2.185TyrGln: 2.185 ± 0.339
1.192TyrArg: 1.192 ± 0.254
3.079TyrSer: 3.079 ± 0.351
2.781TyrThr: 2.781 ± 0.496
2.086TyrVal: 2.086 ± 0.375
0.298TyrTrp: 0.298 ± 0.159
0.993TyrTyr: 0.993 ± 0.297
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 30 proteins (10069 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski