Amino acid dipepetide frequency for Dichanthelium oligosanthes

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.272AlaAla: 15.272 ± 0.09	1.694AlaCys: 1.694 ± 0.015	4.574AlaAsp: 4.574 ± 0.026	5.266AlaGlu: 5.266 ± 0.033	3.213AlaPhe: 3.213 ± 0.021	7.341AlaGly: 7.341 ± 0.041	1.865AlaHis: 1.865 ± 0.015	3.593AlaIle: 3.593 ± 0.021	3.821AlaLys: 3.821 ± 0.025	8.527AlaLeu: 8.527 ± 0.043	2.356AlaMet: 2.356 ± 0.017	2.588AlaAsn: 2.588 ± 0.016	5.51AlaPro: 5.51 ± 0.035	2.6AlaGln: 2.6 ± 0.017	5.824AlaArg: 5.824 ± 0.034	7.844AlaSer: 7.844 ± 0.031	4.94AlaThr: 4.94 ± 0.026	7.259AlaVal: 7.259 ± 0.032	1.051AlaTrp: 1.051 ± 0.011	2.043AlaTyr: 2.043 ± 0.015	0.011AlaXaa: 0.011 ± 0.001
Cys	1.503CysAla: 1.503 ± 0.015	0.617CysCys: 0.617 ± 0.009	0.908CysAsp: 0.908 ± 0.009	0.787CysGlu: 0.787 ± 0.011	0.846CysPhe: 0.846 ± 0.011	1.558CysGly: 1.558 ± 0.015	0.497CysHis: 0.497 ± 0.007	0.879CysIle: 0.879 ± 0.009	0.915CysLys: 0.915 ± 0.012	1.856CysLeu: 1.856 ± 0.016	0.441CysMet: 0.441 ± 0.006	0.713CysAsn: 0.713 ± 0.01	1.077CysPro: 1.077 ± 0.011	0.566CysGln: 0.566 ± 0.008	1.339CysArg: 1.339 ± 0.012	1.887CysSer: 1.887 ± 0.016	0.942CysThr: 0.942 ± 0.011	1.178CysVal: 1.178 ± 0.012	0.262CysTrp: 0.262 ± 0.006	0.545CysTyr: 0.545 ± 0.007	0.002CysXaa: 0.002 ± 0.0
Asp	5.156AspAla: 5.156 ± 0.023	0.924AspCys: 0.924 ± 0.01	4.154AspAsp: 4.154 ± 0.034	3.86AspGlu: 3.86 ± 0.028	1.976AspPhe: 1.976 ± 0.018	4.663AspGly: 4.663 ± 0.028	1.245AspHis: 1.245 ± 0.012	2.539AspIle: 2.539 ± 0.018	2.296AspLys: 2.296 ± 0.018	4.946AspLeu: 4.946 ± 0.025	1.414AspMet: 1.414 ± 0.012	1.712AspAsn: 1.712 ± 0.015	2.867AspPro: 2.867 ± 0.019	1.566AspGln: 1.566 ± 0.014	2.768AspArg: 2.768 ± 0.021	3.561AspSer: 3.561 ± 0.024	2.27AspThr: 2.27 ± 0.016	3.86AspVal: 3.86 ± 0.019	0.703AspTrp: 0.703 ± 0.009	1.388AspTyr: 1.388 ± 0.014	0.006AspXaa: 0.006 ± 0.001
Glu	5.629GluAla: 5.629 ± 0.031	0.866GluCys: 0.866 ± 0.01	3.629GluAsp: 3.629 ± 0.026	5.535GluGlu: 5.535 ± 0.044	1.969GluPhe: 1.969 ± 0.017	3.67GluGly: 3.67 ± 0.02	1.36GluHis: 1.36 ± 0.013	2.763GluIle: 2.763 ± 0.02	3.474GluLys: 3.474 ± 0.027	5.799GluLeu: 5.799 ± 0.031	1.627GluMet: 1.627 ± 0.014	2.019GluAsn: 2.019 ± 0.019	2.421GluPro: 2.421 ± 0.021	2.165GluGln: 2.165 ± 0.017	3.562GluArg: 3.562 ± 0.026	3.575GluSer: 3.575 ± 0.024	2.461GluThr: 2.461 ± 0.016	4.016GluVal: 4.016 ± 0.023	0.722GluTrp: 0.722 ± 0.008	1.443GluTyr: 1.443 ± 0.014	0.006GluXaa: 0.006 ± 0.001
Phe	2.993PheAla: 2.993 ± 0.021	0.819PheCys: 0.819 ± 0.01	2.166PheAsp: 2.166 ± 0.016	1.813PheGlu: 1.813 ± 0.014	1.766PhePhe: 1.766 ± 0.016	2.896PheGly: 2.896 ± 0.021	1.026PheHis: 1.026 ± 0.011	1.569PheIle: 1.569 ± 0.014	1.473PheLys: 1.473 ± 0.015	3.993PheLeu: 3.993 ± 0.023	0.875PheMet: 0.875 ± 0.009	1.271PheAsn: 1.271 ± 0.012	1.887PhePro: 1.887 ± 0.015	1.242PheGln: 1.242 ± 0.013	2.103PheArg: 2.103 ± 0.017	3.214PheSer: 3.214 ± 0.021	1.789PheThr: 1.789 ± 0.015	2.678PheVal: 2.678 ± 0.018	0.518PheTrp: 0.518 ± 0.007	1.099PheTyr: 1.099 ± 0.013	0.003PheXaa: 0.003 ± 0.001
Gly	6.838GlyAla: 6.838 ± 0.034	1.503GlyCys: 1.503 ± 0.017	4.115GlyAsp: 4.115 ± 0.025	3.922GlyGlu: 3.922 ± 0.023	2.941GlyPhe: 2.941 ± 0.019	8.016GlyGly: 8.016 ± 0.057	1.842GlyHis: 1.842 ± 0.015	3.034GlyIle: 3.034 ± 0.022	3.554GlyLys: 3.554 ± 0.025	6.152GlyLeu: 6.152 ± 0.028	1.67GlyMet: 1.67 ± 0.013	2.689GlyAsn: 2.689 ± 0.02	2.986GlyPro: 2.986 ± 0.02	2.164GlyGln: 2.164 ± 0.018	4.937GlyArg: 4.937 ± 0.03	6.18GlySer: 6.18 ± 0.027	3.622GlyThr: 3.622 ± 0.024	4.823GlyVal: 4.823 ± 0.022	1.02GlyTrp: 1.02 ± 0.011	2.099GlyTyr: 2.099 ± 0.017	0.007GlyXaa: 0.007 ± 0.001
His	1.989HisAla: 1.989 ± 0.015	0.558HisCys: 0.558 ± 0.008	1.268HisAsp: 1.268 ± 0.013	1.209HisGlu: 1.209 ± 0.01	0.925HisPhe: 0.925 ± 0.011	2.172HisGly: 2.172 ± 0.017	1.07HisHis: 1.07 ± 0.016	1.0HisIle: 1.0 ± 0.011	0.939HisLys: 0.939 ± 0.01	2.481HisLeu: 2.481 ± 0.017	0.549HisMet: 0.549 ± 0.007	0.772HisAsn: 0.772 ± 0.01	1.56HisPro: 1.56 ± 0.015	0.956HisGln: 0.956 ± 0.01	1.742HisArg: 1.742 ± 0.014	1.686HisSer: 1.686 ± 0.014	0.967HisThr: 0.967 ± 0.01	1.633HisVal: 1.633 ± 0.012	0.303HisTrp: 0.303 ± 0.006	0.655HisTyr: 0.655 ± 0.01	0.002HisXaa: 0.002 ± 0.001
Ile	3.52IleAla: 3.52 ± 0.022	0.896IleCys: 0.896 ± 0.012	2.396IleAsp: 2.396 ± 0.018	2.3IleGlu: 2.3 ± 0.018	1.679IlePhe: 1.679 ± 0.014	2.926IleGly: 2.926 ± 0.02	1.035IleHis: 1.035 ± 0.011	2.074IleIle: 2.074 ± 0.019	2.065IleLys: 2.065 ± 0.016	4.119IleLeu: 4.119 ± 0.025	0.961IleMet: 0.961 ± 0.01	1.536IleAsn: 1.536 ± 0.015	2.372IlePro: 2.372 ± 0.022	1.468IleGln: 1.468 ± 0.014	2.344IleArg: 2.344 ± 0.02	3.574IleSer: 3.574 ± 0.024	2.156IleThr: 2.156 ± 0.017	2.96IleVal: 2.96 ± 0.02	0.548IleTrp: 0.548 ± 0.008	1.164IleTyr: 1.164 ± 0.013	0.004IleXaa: 0.004 ± 0.001
Lys	3.941LysAla: 3.941 ± 0.026	0.755LysCys: 0.755 ± 0.009	2.635LysAsp: 2.635 ± 0.02	3.45LysGlu: 3.45 ± 0.028	1.512LysPhe: 1.512 ± 0.015	2.986LysGly: 2.986 ± 0.019	1.096LysHis: 1.096 ± 0.012	2.266LysIle: 2.266 ± 0.018	3.465LysLys: 3.465 ± 0.035	4.642LysLeu: 4.642 ± 0.029	1.176LysMet: 1.176 ± 0.013	1.799LysAsn: 1.799 ± 0.015	2.353LysPro: 2.353 ± 0.021	1.788LysGln: 1.788 ± 0.015	3.07LysArg: 3.07 ± 0.019	3.218LysSer: 3.218 ± 0.024	2.074LysThr: 2.074 ± 0.019	3.199LysVal: 3.199 ± 0.023	0.58LysTrp: 0.58 ± 0.008	1.216LysTyr: 1.216 ± 0.012	0.003LysXaa: 0.003 ± 0.001
Leu	8.661LeuAla: 8.661 ± 0.038	1.927LeuCys: 1.927 ± 0.017	5.104LeuAsp: 5.104 ± 0.027	5.54LeuGlu: 5.54 ± 0.034	3.5LeuPhe: 3.5 ± 0.022	6.158LeuGly: 6.158 ± 0.031	2.707LeuHis: 2.707 ± 0.018	3.591LeuIle: 3.591 ± 0.025	4.528LeuLys: 4.528 ± 0.029	10.874LeuLeu: 10.874 ± 0.054	2.037LeuMet: 2.037 ± 0.015	2.944LeuAsn: 2.944 ± 0.02	6.06LeuPro: 6.06 ± 0.031	3.97LeuGln: 3.97 ± 0.025	6.528LeuArg: 6.528 ± 0.033	7.747LeuSer: 7.747 ± 0.037	4.269LeuThr: 4.269 ± 0.024	6.75LeuVal: 6.75 ± 0.036	1.178LeuTrp: 1.178 ± 0.012	2.299LeuTyr: 2.299 ± 0.015	0.009LeuXaa: 0.009 ± 0.001
Met	2.766MetAla: 2.766 ± 0.018	0.354MetCys: 0.354 ± 0.005	1.451MetAsp: 1.451 ± 0.012	1.785MetGlu: 1.785 ± 0.013	0.772MetPhe: 0.772 ± 0.01	1.558MetGly: 1.558 ± 0.015	0.573MetHis: 0.573 ± 0.008	0.933MetIle: 0.933 ± 0.01	1.199MetLys: 1.199 ± 0.01	2.257MetLeu: 2.257 ± 0.017	0.669MetMet: 0.669 ± 0.01	0.791MetAsn: 0.791 ± 0.008	1.337MetPro: 1.337 ± 0.011	0.884MetGln: 0.884 ± 0.01	1.345MetArg: 1.345 ± 0.011	1.706MetSer: 1.706 ± 0.013	1.019MetThr: 1.019 ± 0.009	1.69MetVal: 1.69 ± 0.014	0.278MetTrp: 0.278 ± 0.005	0.59MetTyr: 0.59 ± 0.008	0.001MetXaa: 0.001 ± 0.0
Asn	2.659AsnAla: 2.659 ± 0.017	0.686AsnCys: 0.686 ± 0.009	1.607AsnAsp: 1.607 ± 0.016	1.703AsnGlu: 1.703 ± 0.014	1.349AsnPhe: 1.349 ± 0.012	2.79AsnGly: 2.79 ± 0.022	0.842AsnHis: 0.842 ± 0.01	1.806AsnIle: 1.806 ± 0.016	1.667AsnLys: 1.667 ± 0.014	3.503AsnLeu: 3.503 ± 0.028	0.901AsnMet: 0.901 ± 0.01	1.549AsnAsn: 1.549 ± 0.018	1.845AsnPro: 1.845 ± 0.014	1.165AsnGln: 1.165 ± 0.011	1.704AsnArg: 1.704 ± 0.014	2.679AsnSer: 2.679 ± 0.019	1.608AsnThr: 1.608 ± 0.014	2.23AsnVal: 2.23 ± 0.015	0.434AsnTrp: 0.434 ± 0.007	0.957AsnTyr: 0.957 ± 0.011	0.004AsnXaa: 0.004 ± 0.001
Pro	6.138ProAla: 6.138 ± 0.039	0.994ProCys: 0.994 ± 0.011	2.904ProAsp: 2.904 ± 0.02	3.351ProGlu: 3.351 ± 0.025	1.946ProPhe: 1.946 ± 0.015	3.708ProGly: 3.708 ± 0.022	1.233ProHis: 1.233 ± 0.013	1.796ProIle: 1.796 ± 0.014	2.228ProLys: 2.228 ± 0.02	4.762ProLeu: 4.762 ± 0.027	1.102ProMet: 1.102 ± 0.012	1.786ProAsn: 1.786 ± 0.017	5.98ProPro: 5.98 ± 0.07	1.832ProGln: 1.832 ± 0.02	3.622ProArg: 3.622 ± 0.028	5.531ProSer: 5.531 ± 0.032	2.791ProThr: 2.791 ± 0.021	3.68ProVal: 3.68 ± 0.025	0.75ProTrp: 0.75 ± 0.01	1.306ProTyr: 1.306 ± 0.014	0.008ProXaa: 0.008 ± 0.001
Gln	2.772GlnAla: 2.772 ± 0.017	0.59GlnCys: 0.59 ± 0.009	1.578GlnAsp: 1.578 ± 0.013	2.238GlnGlu: 2.238 ± 0.019	1.137GlnPhe: 1.137 ± 0.01	2.188GlnGly: 2.188 ± 0.017	0.958GlnHis: 0.958 ± 0.012	1.469GlnIle: 1.469 ± 0.013	1.736GlnLys: 1.736 ± 0.015	3.424GlnLeu: 3.424 ± 0.023	0.887GlnMet: 0.887 ± 0.01	1.234GlnAsn: 1.234 ± 0.012	1.955GlnPro: 1.955 ± 0.017	2.168GlnGln: 2.168 ± 0.025	2.204GlnArg: 2.204 ± 0.017	2.318GlnSer: 2.318 ± 0.016	1.362GlnThr: 1.362 ± 0.012	2.245GlnVal: 2.245 ± 0.015	0.446GlnTrp: 0.446 ± 0.007	0.86GlnTyr: 0.86 ± 0.01	0.002GlnXaa: 0.002 ± 0.0
Arg	5.598ArgAla: 5.598 ± 0.029	1.308ArgCys: 1.308 ± 0.012	3.071ArgAsp: 3.071 ± 0.021	3.42ArgGlu: 3.42 ± 0.023	2.302ArgPhe: 2.302 ± 0.017	4.356ArgGly: 4.356 ± 0.027	1.717ArgHis: 1.717 ± 0.015	2.521ArgIle: 2.521 ± 0.016	3.226ArgLys: 3.226 ± 0.021	6.151ArgLeu: 6.151 ± 0.032	1.491ArgMet: 1.491 ± 0.014	2.039ArgAsn: 2.039 ± 0.015	3.459ArgPro: 3.459 ± 0.025	2.043ArgGln: 2.043 ± 0.015	6.456ArgArg: 6.456 ± 0.041	4.883ArgSer: 4.883 ± 0.028	2.682ArgThr: 2.682 ± 0.017	3.956ArgVal: 3.956 ± 0.02	1.007ArgTrp: 1.007 ± 0.013	1.594ArgTyr: 1.594 ± 0.014	0.007ArgXaa: 0.007 ± 0.001
Ser	6.929SerAla: 6.929 ± 0.032	1.724SerCys: 1.724 ± 0.015	3.98SerAsp: 3.98 ± 0.023	3.887SerGlu: 3.887 ± 0.027	3.316SerPhe: 3.316 ± 0.02	6.167SerGly: 6.167 ± 0.027	1.748SerHis: 1.748 ± 0.016	3.433SerIle: 3.433 ± 0.018	3.573SerLys: 3.573 ± 0.024	7.68SerLeu: 7.68 ± 0.035	1.971SerMet: 1.971 ± 0.017	2.91SerAsn: 2.91 ± 0.022	5.064SerPro: 5.064 ± 0.035	2.348SerGln: 2.348 ± 0.018	4.704SerArg: 4.704 ± 0.027	9.869SerSer: 9.869 ± 0.058	4.316SerThr: 4.316 ± 0.022	4.958SerVal: 4.958 ± 0.023	1.142SerTrp: 1.142 ± 0.013	2.079SerTyr: 2.079 ± 0.016	0.008SerXaa: 0.008 ± 0.001
Thr	4.694ThrAla: 4.694 ± 0.027	0.951ThrCys: 0.951 ± 0.011	2.307ThrAsp: 2.307 ± 0.018	2.507ThrGlu: 2.507 ± 0.019	1.809ThrPhe: 1.809 ± 0.015	3.639ThrGly: 3.639 ± 0.022	0.938ThrHis: 0.938 ± 0.01	2.169ThrIle: 2.169 ± 0.016	2.107ThrLys: 2.107 ± 0.014	4.284ThrLeu: 4.284 ± 0.023	1.194ThrMet: 1.194 ± 0.012	1.612ThrAsn: 1.612 ± 0.014	2.903ThrPro: 2.903 ± 0.022	1.254ThrGln: 1.254 ± 0.011	2.534ThrArg: 2.534 ± 0.017	4.192ThrSer: 4.192 ± 0.023	2.972ThrThr: 2.972 ± 0.023	3.639ThrVal: 3.639 ± 0.022	0.622ThrTrp: 0.622 ± 0.007	1.264ThrTyr: 1.264 ± 0.013	0.005ThrXaa: 0.005 ± 0.001
Val	7.108ValAla: 7.108 ± 0.036	1.273ValCys: 1.273 ± 0.011	3.881ValAsp: 3.881 ± 0.021	4.088ValGlu: 4.088 ± 0.022	2.604ValPhe: 2.604 ± 0.016	4.49ValGly: 4.49 ± 0.028	1.675ValHis: 1.675 ± 0.014	2.887ValIle: 2.887 ± 0.02	3.071ValLys: 3.071 ± 0.018	7.016ValLeu: 7.016 ± 0.034	1.589ValMet: 1.589 ± 0.013	2.068ValAsn: 2.068 ± 0.017	3.993ValPro: 3.993 ± 0.025	2.303ValGln: 2.303 ± 0.015	3.941ValArg: 3.941 ± 0.024	5.156ValSer: 5.156 ± 0.025	3.431ValThr: 3.431 ± 0.019	5.731ValVal: 5.731 ± 0.034	0.854ValTrp: 0.854 ± 0.011	1.853ValTyr: 1.853 ± 0.014	0.008ValXaa: 0.008 ± 0.001
Trp	1.026TrpAla: 1.026 ± 0.012	0.269TrpCys: 0.269 ± 0.005	0.676TrpAsp: 0.676 ± 0.009	0.72TrpGlu: 0.72 ± 0.009	0.502TrpPhe: 0.502 ± 0.009	0.777TrpGly: 0.777 ± 0.009	0.321TrpHis: 0.321 ± 0.005	0.566TrpIle: 0.566 ± 0.008	0.715TrpLys: 0.715 ± 0.009	1.306TrpLeu: 1.306 ± 0.012	0.355TrpMet: 0.355 ± 0.005	0.571TrpAsn: 0.571 ± 0.008	0.609TrpPro: 0.609 ± 0.009	0.457TrpGln: 0.457 ± 0.007	1.069TrpArg: 1.069 ± 0.013	1.017TrpSer: 1.017 ± 0.011	0.664TrpThr: 0.664 ± 0.008	0.836TrpVal: 0.836 ± 0.01	0.253TrpTrp: 0.253 ± 0.006	0.337TrpTyr: 0.337 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.99TyrAla: 1.99 ± 0.016	0.61TyrCys: 0.61 ± 0.009	1.463TyrAsp: 1.463 ± 0.013	1.327TyrGlu: 1.327 ± 0.013	1.124TyrPhe: 1.124 ± 0.011	2.048TyrGly: 2.048 ± 0.019	0.687TyrHis: 0.687 ± 0.008	1.203TyrIle: 1.203 ± 0.011	1.165TyrLys: 1.165 ± 0.013	2.597TyrLeu: 2.597 ± 0.016	0.692TyrMet: 0.692 ± 0.008	1.08TyrAsn: 1.08 ± 0.012	1.203TyrPro: 1.203 ± 0.014	0.832TyrGln: 0.832 ± 0.009	1.481TyrArg: 1.481 ± 0.014	1.964TyrSer: 1.964 ± 0.016	1.257TyrThr: 1.257 ± 0.012	1.694TyrVal: 1.694 ± 0.012	0.375TyrTrp: 0.375 ± 0.007	0.94TyrTyr: 0.94 ± 0.011	0.002TyrXaa: 0.002 ± 0.0
Xaa	0.01XaaAla: 0.01 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.006XaaAsp: 0.006 ± 0.001	0.006XaaGlu: 0.006 ± 0.001	0.003XaaPhe: 0.003 ± 0.001	0.008XaaGly: 0.008 ± 0.001	0.002XaaHis: 0.002 ± 0.0	0.004XaaIle: 0.004 ± 0.001	0.005XaaLys: 0.005 ± 0.001	0.011XaaLeu: 0.011 ± 0.001	0.002XaaMet: 0.002 ± 0.001	0.002XaaAsn: 0.002 ± 0.001	0.006XaaPro: 0.006 ± 0.001	0.003XaaGln: 0.003 ± 0.001	0.008XaaArg: 0.008 ± 0.001	0.008XaaSer: 0.008 ± 0.001	0.003XaaThr: 0.003 ± 0.001	0.006XaaVal: 0.006 ± 0.001	0.002XaaTrp: 0.002 ± 0.0	0.002XaaTyr: 0.002 ± 0.0	0.005XaaXaa: 0.005 ± 0.001

Statistics based on 26451 proteins (9714948 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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