Amino acid dipepetide frequency for Rhododendron virus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.757AlaAla: 6.757 ± 0.355
0.676AlaCys: 0.676 ± 0.354
3.378AlaAsp: 3.378 ± 0.826
13.514AlaGlu: 13.514 ± 3.305
2.027AlaPhe: 2.027 ± 0.236
16.892AlaGly: 16.892 ± 2.834
0.676AlaHis: 0.676 ± 0.354
3.378AlaIle: 3.378 ± 0.826
0.676AlaLys: 0.676 ± 0.354
9.459AlaLeu: 9.459 ± 0.238
1.351AlaMet: 1.351 ± 0.707
2.027AlaAsn: 2.027 ± 0.236
2.703AlaPro: 2.703 ± 1.18
2.703AlaGln: 2.703 ± 1.18
10.135AlaArg: 10.135 ± 1.181
6.757AlaSer: 6.757 ± 0.355
0.676AlaThr: 0.676 ± 0.354
7.432AlaVal: 7.432 ± 1.299
0.676AlaTrp: 0.676 ± 0.354
2.027AlaTyr: 2.027 ± 0.236
0.0AlaXaa: 0.0 ± 0.0
Cys
0.676CysAla: 0.676 ± 0.354
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.351CysGlu: 1.351 ± 0.707
0.676CysPhe: 0.676 ± 0.354
2.027CysGly: 2.027 ± 0.236
0.0CysHis: 0.0 ± 0.0
0.676CysIle: 0.676 ± 0.354
1.351CysLys: 1.351 ± 0.707
2.027CysLeu: 2.027 ± 1.061
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
2.027CysGln: 2.027 ± 0.236
0.676CysArg: 0.676 ± 0.354
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
1.351CysTrp: 1.351 ± 0.59
1.351CysTyr: 1.351 ± 0.707
0.0CysXaa: 0.0 ± 0.0
Asp
6.757AspAla: 6.757 ± 0.942
0.676AspCys: 0.676 ± 0.354
4.73AspAsp: 4.73 ± 1.416
8.108AspGlu: 8.108 ± 2.242
1.351AspPhe: 1.351 ± 0.707
4.054AspGly: 4.054 ± 0.472
0.0AspHis: 0.0 ± 0.0
2.703AspIle: 2.703 ± 1.415
2.703AspLys: 2.703 ± 1.18
5.405AspLeu: 5.405 ± 0.235
0.0AspMet: 0.0 ± 0.0
1.351AspAsn: 1.351 ± 0.707
0.676AspPro: 0.676 ± 0.354
3.378AspGln: 3.378 ± 0.471
5.405AspArg: 5.405 ± 0.235
3.378AspSer: 3.378 ± 0.471
2.027AspThr: 2.027 ± 0.236
2.027AspVal: 2.027 ± 1.534
1.351AspTrp: 1.351 ± 0.707
0.676AspTyr: 0.676 ± 0.354
0.0AspXaa: 0.0 ± 0.0
Glu
11.486GluAla: 11.486 ± 1.771
0.676GluCys: 0.676 ± 0.354
8.784GluAsp: 8.784 ± 0.591
6.757GluGlu: 6.757 ± 1.652
2.703GluPhe: 2.703 ± 0.117
6.081GluGly: 6.081 ± 3.183
2.703GluHis: 2.703 ± 0.117
5.405GluIle: 5.405 ± 1.062
0.676GluLys: 0.676 ± 0.354
4.054GluLeu: 4.054 ± 0.472
2.027GluMet: 2.027 ± 1.061
0.0GluAsn: 0.0 ± 0.0
10.811GluPro: 10.811 ± 3.422
2.027GluGln: 2.027 ± 0.236
8.784GluArg: 8.784 ± 0.591
1.351GluSer: 1.351 ± 0.59
2.027GluThr: 2.027 ± 0.236
10.811GluVal: 10.811 ± 0.828
0.676GluTrp: 0.676 ± 0.354
0.676GluTyr: 0.676 ± 0.354
0.0GluXaa: 0.0 ± 0.0
Phe
1.351PheAla: 1.351 ± 0.59
0.0PheCys: 0.0 ± 0.0
0.676PheAsp: 0.676 ± 0.354
1.351PheGlu: 1.351 ± 0.707
0.676PhePhe: 0.676 ± 0.354
2.703PheGly: 2.703 ± 0.117
0.676PheHis: 0.676 ± 0.354
2.703PheIle: 2.703 ± 0.117
2.703PheLys: 2.703 ± 1.18
4.73PheLeu: 4.73 ± 1.179
1.351PheMet: 1.351 ± 0.707
1.351PheAsn: 1.351 ± 0.707
2.027PhePro: 2.027 ± 0.236
0.0PheGln: 0.0 ± 0.0
4.73PheArg: 4.73 ± 1.179
0.676PheSer: 0.676 ± 0.354
4.054PheThr: 4.054 ± 1.77
4.054PheVal: 4.054 ± 0.472
2.027PheTrp: 2.027 ± 0.236
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.081GlyAla: 6.081 ± 3.303
0.0GlyCys: 0.0 ± 0.0
4.054GlyAsp: 4.054 ± 0.825
8.108GlyGlu: 8.108 ± 0.352
2.703GlyPhe: 2.703 ± 0.117
15.541GlyGly: 15.541 ± 0.946
0.0GlyHis: 0.0 ± 0.0
10.135GlyIle: 10.135 ± 1.414
4.73GlyLys: 4.73 ± 1.416
6.081GlyLeu: 6.081 ± 0.589
2.027GlyMet: 2.027 ± 0.236
2.027GlyAsn: 2.027 ± 1.061
2.703GlyPro: 2.703 ± 1.415
3.378GlyGln: 3.378 ± 0.471
14.189GlyArg: 14.189 ± 0.356
2.703GlySer: 2.703 ± 0.117
6.081GlyThr: 6.081 ± 0.709
3.378GlyVal: 3.378 ± 0.826
1.351GlyTrp: 1.351 ± 0.707
0.676GlyTyr: 0.676 ± 0.354
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.676HisAsp: 0.676 ± 0.354
2.027HisGlu: 2.027 ± 0.236
1.351HisPhe: 1.351 ± 0.59
2.027HisGly: 2.027 ± 1.061
0.676HisHis: 0.676 ± 0.354
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
0.676HisLeu: 0.676 ± 0.354
0.676HisMet: 0.676 ± 0.354
0.676HisAsn: 0.676 ± 0.354
0.0HisPro: 0.0 ± 0.0
1.351HisGln: 1.351 ± 0.59
4.054HisArg: 4.054 ± 0.825
0.0HisSer: 0.0 ± 0.0
1.351HisThr: 1.351 ± 0.59
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.351IleAla: 1.351 ± 0.707
0.676IleCys: 0.676 ± 0.354
5.405IleAsp: 5.405 ± 1.062
0.676IleGlu: 0.676 ± 0.354
2.703IlePhe: 2.703 ± 1.18
5.405IleGly: 5.405 ± 0.235
2.027IleHis: 2.027 ± 0.236
4.054IleIle: 4.054 ± 2.122
8.108IleLys: 8.108 ± 0.352
3.378IleLeu: 3.378 ± 1.769
2.027IleMet: 2.027 ± 0.236
0.0IleAsn: 0.0 ± 0.0
0.0IlePro: 0.0 ± 0.0
0.676IleGln: 0.676 ± 0.354
6.081IleArg: 6.081 ± 0.589
2.703IleSer: 2.703 ± 1.415
0.676IleThr: 0.676 ± 0.354
2.027IleVal: 2.027 ± 1.061
2.027IleTrp: 2.027 ± 0.236
0.676IleTyr: 0.676 ± 0.354
0.0IleXaa: 0.0 ± 0.0
Lys
2.027LysAla: 2.027 ± 0.236
0.676LysCys: 0.676 ± 0.354
2.027LysAsp: 2.027 ± 0.236
1.351LysGlu: 1.351 ± 0.59
4.73LysPhe: 4.73 ± 1.179
3.378LysGly: 3.378 ± 0.471
0.676LysHis: 0.676 ± 0.944
0.676LysIle: 0.676 ± 0.354
4.054LysLys: 4.054 ± 0.472
3.378LysLeu: 3.378 ± 0.471
1.351LysMet: 1.351 ± 0.59
3.378LysAsn: 3.378 ± 0.826
0.676LysPro: 0.676 ± 0.354
2.703LysGln: 2.703 ± 0.117
4.73LysArg: 4.73 ± 1.416
0.0LysSer: 0.0 ± 0.0
4.054LysThr: 4.054 ± 1.77
5.405LysVal: 5.405 ± 2.36
0.0LysTrp: 0.0 ± 0.0
2.027LysTyr: 2.027 ± 0.236
0.0LysXaa: 0.0 ± 0.0
Leu
4.73LeuAla: 4.73 ± 1.416
2.027LeuCys: 2.027 ± 0.236
6.081LeuAsp: 6.081 ± 0.589
8.108LeuGlu: 8.108 ± 2.947
1.351LeuPhe: 1.351 ± 0.707
5.405LeuGly: 5.405 ± 1.532
0.0LeuHis: 0.0 ± 0.0
2.027LeuIle: 2.027 ± 0.236
2.027LeuLys: 2.027 ± 0.236
7.432LeuLeu: 7.432 ± 1.296
0.676LeuMet: 0.676 ± 0.354
1.351LeuAsn: 1.351 ± 0.707
6.081LeuPro: 6.081 ± 0.709
2.027LeuGln: 2.027 ± 0.236
12.162LeuArg: 12.162 ± 0.12
4.73LeuSer: 4.73 ± 2.476
4.054LeuThr: 4.054 ± 0.472
3.378LeuVal: 3.378 ± 0.471
1.351LeuTrp: 1.351 ± 0.707
3.378LeuTyr: 3.378 ± 1.769
0.0LeuXaa: 0.0 ± 0.0
Met
1.351MetAla: 1.351 ± 0.59
0.0MetCys: 0.0 ± 0.0
1.351MetAsp: 1.351 ± 0.707
4.054MetGlu: 4.054 ± 0.472
0.0MetPhe: 0.0 ± 0.0
1.351MetGly: 1.351 ± 0.59
0.0MetHis: 0.0 ± 0.0
1.351MetIle: 1.351 ± 0.707
0.676MetLys: 0.676 ± 0.354
2.703MetLeu: 2.703 ± 1.415
0.676MetMet: 0.676 ± 0.354
0.676MetAsn: 0.676 ± 0.354
1.351MetPro: 1.351 ± 0.59
1.351MetGln: 1.351 ± 0.59
1.351MetArg: 1.351 ± 0.707
0.0MetSer: 0.0 ± 0.0
0.676MetThr: 0.676 ± 0.354
1.351MetVal: 1.351 ± 0.707
0.676MetTrp: 0.676 ± 0.354
0.676MetTyr: 0.676 ± 0.354
0.0MetXaa: 0.0 ± 0.0
Asn
2.027AsnAla: 2.027 ± 0.236
0.0AsnCys: 0.0 ± 0.0
2.703AsnAsp: 2.703 ± 0.117
2.703AsnGlu: 2.703 ± 0.117
1.351AsnPhe: 1.351 ± 0.59
1.351AsnGly: 1.351 ± 0.707
1.351AsnHis: 1.351 ± 0.707
2.703AsnIle: 2.703 ± 0.117
0.676AsnLys: 0.676 ± 0.354
1.351AsnLeu: 1.351 ± 0.707
0.0AsnMet: 0.0 ± 0.0
0.676AsnAsn: 0.676 ± 0.354
0.676AsnPro: 0.676 ± 0.354
0.0AsnGln: 0.0 ± 0.0
1.351AsnArg: 1.351 ± 0.707
0.676AsnSer: 0.676 ± 0.354
0.676AsnThr: 0.676 ± 0.354
4.054AsnVal: 4.054 ± 0.472
0.676AsnTrp: 0.676 ± 0.354
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
8.784ProAla: 8.784 ± 3.186
0.0ProCys: 0.0 ± 0.0
1.351ProAsp: 1.351 ± 0.707
4.73ProGlu: 4.73 ± 1.416
2.027ProPhe: 2.027 ± 1.061
2.027ProGly: 2.027 ± 0.236
0.0ProHis: 0.0 ± 0.0
4.054ProIle: 4.054 ± 0.825
2.703ProLys: 2.703 ± 1.18
4.054ProLeu: 4.054 ± 0.472
1.351ProMet: 1.351 ± 0.707
1.351ProAsn: 1.351 ± 0.59
4.054ProPro: 4.054 ± 1.77
0.0ProGln: 0.0 ± 0.0
2.703ProArg: 2.703 ± 0.117
3.378ProSer: 3.378 ± 0.471
1.351ProThr: 1.351 ± 0.59
0.0ProVal: 0.0 ± 0.0
0.676ProTrp: 0.676 ± 0.354
1.351ProTyr: 1.351 ± 0.707
0.0ProXaa: 0.0 ± 0.0
Gln
7.432GlnAla: 7.432 ± 1.299
1.351GlnCys: 1.351 ± 0.707
0.0GlnAsp: 0.0 ± 0.0
1.351GlnGlu: 1.351 ± 0.59
0.676GlnPhe: 0.676 ± 0.354
4.054GlnGly: 4.054 ± 1.77
0.676GlnHis: 0.676 ± 0.354
2.703GlnIle: 2.703 ± 0.117
2.027GlnLys: 2.027 ± 0.236
0.0GlnLeu: 0.0 ± 0.0
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
3.378GlnGln: 3.378 ± 0.826
1.351GlnArg: 1.351 ± 0.59
0.676GlnSer: 0.676 ± 0.354
3.378GlnThr: 3.378 ± 0.826
4.054GlnVal: 4.054 ± 0.472
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
14.865ArgAla: 14.865 ± 0.003
2.027ArgCys: 2.027 ± 0.236
2.027ArgAsp: 2.027 ± 1.061
3.378ArgGlu: 3.378 ± 1.769
5.405ArgPhe: 5.405 ± 0.235
9.459ArgGly: 9.459 ± 0.238
0.676ArgHis: 0.676 ± 0.354
2.703ArgIle: 2.703 ± 0.117
4.054ArgLys: 4.054 ± 0.472
9.459ArgLeu: 9.459 ± 1.06
3.378ArgMet: 3.378 ± 1.12
6.757ArgAsn: 6.757 ± 0.942
6.081ArgPro: 6.081 ± 0.709
2.703ArgGln: 2.703 ± 0.117
7.432ArgArg: 7.432 ± 1.299
8.784ArgSer: 8.784 ± 1.889
2.027ArgThr: 2.027 ± 0.236
4.73ArgVal: 4.73 ± 0.119
2.703ArgTrp: 2.703 ± 0.117
2.027ArgTyr: 2.027 ± 1.061
0.0ArgXaa: 0.0 ± 0.0
Ser
6.081SerAla: 6.081 ± 0.589
2.703SerCys: 2.703 ± 1.415
5.405SerAsp: 5.405 ± 0.235
1.351SerGlu: 1.351 ± 0.707
0.676SerPhe: 0.676 ± 0.354
4.73SerGly: 4.73 ± 0.119
0.676SerHis: 0.676 ± 0.354
0.676SerIle: 0.676 ± 0.354
1.351SerLys: 1.351 ± 0.59
5.405SerLeu: 5.405 ± 1.062
0.676SerMet: 0.676 ± 0.354
2.027SerAsn: 2.027 ± 0.236
1.351SerPro: 1.351 ± 0.707
0.0SerGln: 0.0 ± 0.0
6.081SerArg: 6.081 ± 0.589
4.054SerSer: 4.054 ± 0.825
2.027SerThr: 2.027 ± 0.236
2.027SerVal: 2.027 ± 0.236
0.676SerTrp: 0.676 ± 0.354
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
2.703ThrAla: 2.703 ± 0.117
0.0ThrCys: 0.0 ± 0.0
4.054ThrAsp: 4.054 ± 0.472
4.054ThrGlu: 4.054 ± 1.77
2.703ThrPhe: 2.703 ± 0.117
4.73ThrGly: 4.73 ± 1.416
2.027ThrHis: 2.027 ± 0.236
0.0ThrIle: 0.0 ± 0.0
1.351ThrLys: 1.351 ± 0.707
1.351ThrLeu: 1.351 ± 0.707
2.703ThrMet: 2.703 ± 1.18
0.0ThrAsn: 0.0 ± 0.0
2.027ThrPro: 2.027 ± 0.236
2.703ThrGln: 2.703 ± 1.18
2.703ThrArg: 2.703 ± 1.18
2.027ThrSer: 2.027 ± 0.236
4.73ThrThr: 4.73 ± 1.416
3.378ThrVal: 3.378 ± 0.826
0.0ThrTrp: 0.0 ± 0.0
1.351ThrTyr: 1.351 ± 0.707
0.0ThrXaa: 0.0 ± 0.0
Val
6.757ValAla: 6.757 ± 1.652
1.351ValCys: 1.351 ± 0.59
3.378ValAsp: 3.378 ± 0.826
7.432ValGlu: 7.432 ± 0.001
2.703ValPhe: 2.703 ± 1.18
2.027ValGly: 2.027 ± 0.236
2.703ValHis: 2.703 ± 0.117
4.054ValIle: 4.054 ± 0.825
6.081ValLys: 6.081 ± 2.006
4.73ValLeu: 4.73 ± 0.119
0.676ValMet: 0.676 ± 0.354
0.676ValAsn: 0.676 ± 0.354
2.703ValPro: 2.703 ± 0.117
2.027ValGln: 2.027 ± 1.534
3.378ValArg: 3.378 ± 1.769
2.703ValSer: 2.703 ± 0.117
3.378ValThr: 3.378 ± 0.826
3.378ValVal: 3.378 ± 0.826
0.0ValTrp: 0.0 ± 0.0
3.378ValTyr: 3.378 ± 0.826
0.0ValXaa: 0.0 ± 0.0
Trp
2.027TrpAla: 2.027 ± 0.236
0.676TrpCys: 0.676 ± 0.354
0.0TrpAsp: 0.0 ± 0.0
5.405TrpGlu: 5.405 ± 1.062
0.676TrpPhe: 0.676 ± 0.354
1.351TrpGly: 1.351 ± 0.707
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
2.027TrpLeu: 2.027 ± 1.061
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.676TrpPro: 0.676 ± 0.354
0.0TrpGln: 0.0 ± 0.0
1.351TrpArg: 1.351 ± 0.707
0.676TrpSer: 0.676 ± 0.354
0.676TrpThr: 0.676 ± 0.354
0.676TrpVal: 0.676 ± 0.354
0.0TrpTrp: 0.0 ± 0.0
0.676TrpTyr: 0.676 ± 0.354
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.676TyrAla: 0.676 ± 0.354
0.676TyrCys: 0.676 ± 0.354
0.676TyrAsp: 0.676 ± 0.354
2.703TyrGlu: 2.703 ± 0.117
1.351TyrPhe: 1.351 ± 0.59
1.351TyrGly: 1.351 ± 0.707
0.0TyrHis: 0.0 ± 0.0
0.676TyrIle: 0.676 ± 0.354
1.351TyrLys: 1.351 ± 0.59
0.676TyrLeu: 0.676 ± 0.354
0.0TyrMet: 0.0 ± 0.0
0.676TyrAsn: 0.676 ± 0.354
1.351TyrPro: 1.351 ± 0.707
0.676TyrGln: 0.676 ± 0.354
2.703TyrArg: 2.703 ± 1.415
2.703TyrSer: 2.703 ± 0.117
0.676TyrThr: 0.676 ± 0.354
1.351TyrVal: 1.351 ± 0.707
0.676TyrTrp: 0.676 ± 0.354
0.676TyrTyr: 0.676 ± 0.354
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1481 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski