Amino acid dipepetide frequency for Beihai tombus-like virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.728AlaAla: 4.728 ± 1.772
1.576AlaCys: 1.576 ± 1.036
4.728AlaAsp: 4.728 ± 1.86
4.728AlaGlu: 4.728 ± 1.772
1.576AlaPhe: 1.576 ± 0.516
8.668AlaGly: 8.668 ± 3.559
0.788AlaHis: 0.788 ± 0.6
5.516AlaIle: 5.516 ± 1.958
3.94AlaLys: 3.94 ± 1.79
6.304AlaLeu: 6.304 ± 0.415
1.576AlaMet: 1.576 ± 0.803
3.152AlaAsn: 3.152 ± 1.7
4.728AlaPro: 4.728 ± 1.86
0.788AlaGln: 0.788 ± 0.518
3.152AlaArg: 3.152 ± 1.557
4.728AlaSer: 4.728 ± 1.772
1.576AlaThr: 1.576 ± 0.803
7.88AlaVal: 7.88 ± 2.598
1.576AlaTrp: 1.576 ± 0.803
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.788CysAla: 0.788 ± 0.518
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.364CysGly: 2.364 ± 0.875
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.788CysLys: 0.788 ± 0.518
0.788CysLeu: 0.788 ± 0.518
0.788CysMet: 0.788 ± 0.776
0.0CysAsn: 0.0 ± 0.0
2.364CysPro: 2.364 ± 1.554
0.788CysGln: 0.788 ± 0.518
0.788CysArg: 0.788 ± 0.518
1.576CysSer: 1.576 ± 1.036
0.0CysThr: 0.0 ± 0.0
2.364CysVal: 2.364 ± 0.311
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.152AspAla: 3.152 ± 0.291
0.788AspCys: 0.788 ± 0.518
5.516AspAsp: 5.516 ± 0.826
1.576AspGlu: 1.576 ± 0.645
1.576AspPhe: 1.576 ± 0.516
7.092AspGly: 7.092 ± 1.998
2.364AspHis: 2.364 ± 0.992
3.94AspIle: 3.94 ± 1.79
1.576AspLys: 1.576 ± 0.645
3.94AspLeu: 3.94 ± 1.754
0.788AspMet: 0.788 ± 0.518
2.364AspAsn: 2.364 ± 0.311
4.728AspPro: 4.728 ± 0.939
2.364AspGln: 2.364 ± 0.311
2.364AspArg: 2.364 ± 0.842
0.788AspSer: 0.788 ± 0.776
3.152AspThr: 3.152 ± 0.705
4.728AspVal: 4.728 ± 1.421
2.364AspTrp: 2.364 ± 0.842
3.152AspTyr: 3.152 ± 1.032
0.0AspXaa: 0.0 ± 0.0
Glu
3.152GluAla: 3.152 ± 1.29
0.0GluCys: 0.0 ± 0.0
3.152GluAsp: 3.152 ± 1.29
3.152GluGlu: 3.152 ± 1.064
3.152GluPhe: 3.152 ± 0.291
3.152GluGly: 3.152 ± 1.29
3.94GluHis: 3.94 ± 2.59
3.152GluIle: 3.152 ± 1.29
0.788GluLys: 0.788 ± 0.518
5.516GluLeu: 5.516 ± 0.306
2.364GluMet: 2.364 ± 0.559
2.364GluAsn: 2.364 ± 1.187
4.728GluPro: 4.728 ± 1.985
3.152GluGln: 3.152 ± 1.3
7.88GluArg: 7.88 ± 2.032
4.728GluSer: 4.728 ± 0.857
4.728GluThr: 4.728 ± 2.732
7.092GluVal: 7.092 ± 2.706
0.788GluTrp: 0.788 ± 0.776
1.576GluTyr: 1.576 ± 0.645
0.0GluXaa: 0.0 ± 0.0
Phe
1.576PheAla: 1.576 ± 0.516
0.788PheCys: 0.788 ± 0.518
3.94PheAsp: 3.94 ± 2.59
3.94PheGlu: 3.94 ± 1.754
3.152PhePhe: 3.152 ± 0.291
2.364PheGly: 2.364 ± 0.311
1.576PheHis: 1.576 ± 1.2
0.0PheIle: 0.0 ± 0.0
0.788PheLys: 0.788 ± 0.518
4.728PheLeu: 4.728 ± 1.293
0.0PheMet: 0.0 ± 0.0
1.576PheAsn: 1.576 ± 0.645
1.576PhePro: 1.576 ± 0.803
1.576PheGln: 1.576 ± 0.516
0.0PheArg: 0.0 ± 0.0
3.152PheSer: 3.152 ± 0.705
2.364PheThr: 2.364 ± 0.842
3.94PheVal: 3.94 ± 2.141
0.0PheTrp: 0.0 ± 0.0
1.576PheTyr: 1.576 ± 1.036
0.0PheXaa: 0.0 ± 0.0
Gly
7.092GlyAla: 7.092 ± 1.907
3.152GlyCys: 3.152 ± 1.286
7.092GlyAsp: 7.092 ± 1.998
7.092GlyGlu: 7.092 ± 3.233
2.364GlyPhe: 2.364 ± 0.875
8.668GlyGly: 8.668 ± 1.32
0.0GlyHis: 0.0 ± 0.0
6.304GlyIle: 6.304 ± 2.065
2.364GlyLys: 2.364 ± 1.33
6.304GlyLeu: 6.304 ± 2.128
3.152GlyMet: 3.152 ± 1.286
1.576GlyAsn: 1.576 ± 0.645
3.152GlyPro: 3.152 ± 2.081
0.0GlyGln: 0.0 ± 0.0
5.516GlyArg: 5.516 ± 1.808
2.364GlySer: 2.364 ± 1.8
3.94GlyThr: 3.94 ± 0.351
5.516GlyVal: 5.516 ± 1.362
0.788GlyTrp: 0.788 ± 0.6
3.152GlyTyr: 3.152 ± 1.032
0.0GlyXaa: 0.0 ± 0.0
His
3.152HisAla: 3.152 ± 1.29
0.0HisCys: 0.0 ± 0.0
0.788HisAsp: 0.788 ± 0.518
1.576HisGlu: 1.576 ± 0.516
0.0HisPhe: 0.0 ± 0.0
1.576HisGly: 1.576 ± 0.645
0.0HisHis: 0.0 ± 0.0
1.576HisIle: 1.576 ± 0.645
0.788HisLys: 0.788 ± 0.518
1.576HisLeu: 1.576 ± 0.516
0.0HisMet: 0.0 ± 0.0
1.576HisAsn: 1.576 ± 0.803
0.0HisPro: 0.0 ± 0.0
2.364HisGln: 2.364 ± 0.842
0.788HisArg: 0.788 ± 0.6
1.576HisSer: 1.576 ± 0.516
1.576HisThr: 1.576 ± 1.2
1.576HisVal: 1.576 ± 0.803
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.516IleAla: 5.516 ± 1.882
0.788IleCys: 0.788 ± 0.776
2.364IleAsp: 2.364 ± 0.842
2.364IleGlu: 2.364 ± 1.554
3.152IlePhe: 3.152 ± 2.072
3.152IleGly: 3.152 ± 1.064
0.0IleHis: 0.0 ± 0.0
2.364IleIle: 2.364 ± 0.875
1.576IleLys: 1.576 ± 1.036
2.364IleLeu: 2.364 ± 1.187
1.576IleMet: 1.576 ± 1.036
2.364IleAsn: 2.364 ± 0.311
3.152IlePro: 3.152 ± 1.286
2.364IleGln: 2.364 ± 0.842
1.576IleArg: 1.576 ± 1.553
3.94IleSer: 3.94 ± 1.297
4.728IleThr: 4.728 ± 1.985
2.364IleVal: 2.364 ± 0.311
0.0IleTrp: 0.0 ± 0.0
0.788IleTyr: 0.788 ± 0.518
0.0IleXaa: 0.0 ± 0.0
Lys
2.364LysAla: 2.364 ± 1.462
0.788LysCys: 0.788 ± 0.518
3.152LysAsp: 3.152 ± 1.3
2.364LysGlu: 2.364 ± 0.311
1.576LysPhe: 1.576 ± 1.036
2.364LysGly: 2.364 ± 1.554
0.0LysHis: 0.0 ± 0.0
2.364LysIle: 2.364 ± 0.842
1.576LysLys: 1.576 ± 1.036
4.728LysLeu: 4.728 ± 0.939
2.364LysMet: 2.364 ± 0.941
1.576LysAsn: 1.576 ± 1.036
3.152LysPro: 3.152 ± 1.286
2.364LysGln: 2.364 ± 0.311
4.728LysArg: 4.728 ± 1.751
1.576LysSer: 1.576 ± 0.516
3.94LysThr: 3.94 ± 1.297
3.94LysVal: 3.94 ± 1.79
0.0LysTrp: 0.0 ± 0.0
3.152LysTyr: 3.152 ± 1.3
0.0LysXaa: 0.0 ± 0.0
Leu
4.728LeuAla: 4.728 ± 1.86
0.788LeuCys: 0.788 ± 0.518
5.516LeuAsp: 5.516 ± 1.786
5.516LeuGlu: 5.516 ± 2.802
1.576LeuPhe: 1.576 ± 0.803
6.304LeuGly: 6.304 ± 2.065
2.364LeuHis: 2.364 ± 1.554
3.152LeuIle: 3.152 ± 1.286
6.304LeuLys: 6.304 ± 1.489
8.668LeuLeu: 8.668 ± 0.644
3.94LeuMet: 3.94 ± 2.141
4.728LeuAsn: 4.728 ± 0.939
3.152LeuPro: 3.152 ± 1.032
3.152LeuGln: 3.152 ± 0.705
7.88LeuArg: 7.88 ± 4.653
6.304LeuSer: 6.304 ± 1.052
0.788LeuThr: 0.788 ± 0.6
3.94LeuVal: 3.94 ± 0.816
0.0LeuTrp: 0.0 ± 0.0
3.152LeuTyr: 3.152 ± 0.705
0.0LeuXaa: 0.0 ± 0.0
Met
2.364MetAla: 2.364 ± 0.875
0.788MetCys: 0.788 ± 0.518
0.0MetAsp: 0.0 ± 0.0
2.364MetGlu: 2.364 ± 0.992
0.788MetPhe: 0.788 ± 0.6
2.364MetGly: 2.364 ± 0.311
0.788MetHis: 0.788 ± 0.776
0.788MetIle: 0.788 ± 0.518
1.576MetLys: 1.576 ± 0.516
2.364MetLeu: 2.364 ± 0.992
0.788MetMet: 0.788 ± 0.518
3.94MetAsn: 3.94 ± 0.78
0.788MetPro: 0.788 ± 0.6
0.0MetGln: 0.0 ± 0.0
2.364MetArg: 2.364 ± 0.311
0.788MetSer: 0.788 ± 0.518
1.576MetThr: 1.576 ± 1.2
0.788MetVal: 0.788 ± 0.6
1.576MetTrp: 1.576 ± 1.036
3.152MetTyr: 3.152 ± 1.286
0.0MetXaa: 0.0 ± 0.0
Asn
1.576AsnAla: 1.576 ± 0.803
0.788AsnCys: 0.788 ± 0.518
3.152AsnAsp: 3.152 ± 0.291
3.152AsnGlu: 3.152 ± 1.032
1.576AsnPhe: 1.576 ± 0.516
5.516AsnGly: 5.516 ± 2.541
2.364AsnHis: 2.364 ± 2.329
1.576AsnIle: 1.576 ± 0.516
0.788AsnLys: 0.788 ± 0.6
3.152AsnLeu: 3.152 ± 1.064
1.576AsnMet: 1.576 ± 0.516
3.152AsnAsn: 3.152 ± 0.291
2.364AsnPro: 2.364 ± 0.311
0.788AsnGln: 0.788 ± 0.6
2.364AsnArg: 2.364 ± 1.462
1.576AsnSer: 1.576 ± 1.2
4.728AsnThr: 4.728 ± 1.772
3.94AsnVal: 3.94 ± 0.816
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.152ProAla: 3.152 ± 1.7
0.788ProCys: 0.788 ± 0.518
2.364ProAsp: 2.364 ± 0.842
4.728ProGlu: 4.728 ± 0.621
3.152ProPhe: 3.152 ± 1.607
1.576ProGly: 1.576 ± 1.036
0.0ProHis: 0.0 ± 0.0
1.576ProIle: 1.576 ± 0.516
1.576ProLys: 1.576 ± 0.645
3.152ProLeu: 3.152 ± 0.705
0.0ProMet: 0.0 ± 0.0
2.364ProAsn: 2.364 ± 0.992
2.364ProPro: 2.364 ± 0.992
3.152ProGln: 3.152 ± 1.064
7.092ProArg: 7.092 ± 2.041
2.364ProSer: 2.364 ± 1.554
3.152ProThr: 3.152 ± 0.705
3.94ProVal: 3.94 ± 0.816
3.152ProTrp: 3.152 ± 0.291
0.788ProTyr: 0.788 ± 0.6
0.0ProXaa: 0.0 ± 0.0
Gln
2.364GlnAla: 2.364 ± 0.311
0.788GlnCys: 0.788 ± 0.518
0.788GlnAsp: 0.788 ± 0.6
3.152GlnGlu: 3.152 ± 0.291
0.0GlnPhe: 0.0 ± 0.0
0.788GlnGly: 0.788 ± 0.518
0.788GlnHis: 0.788 ± 0.518
0.0GlnIle: 0.0 ± 0.0
1.576GlnLys: 1.576 ± 1.036
3.152GlnLeu: 3.152 ± 1.3
0.788GlnMet: 0.788 ± 0.6
2.364GlnAsn: 2.364 ± 0.311
1.576GlnPro: 1.576 ± 0.645
0.788GlnGln: 0.788 ± 0.6
0.0GlnArg: 0.0 ± 0.0
3.94GlnSer: 3.94 ± 1.272
0.788GlnThr: 0.788 ± 0.6
1.576GlnVal: 1.576 ± 0.516
0.0GlnTrp: 0.0 ± 0.0
0.788GlnTyr: 0.788 ± 0.6
0.0GlnXaa: 0.0 ± 0.0
Arg
7.092ArgAla: 7.092 ± 0.947
0.788ArgCys: 0.788 ± 0.776
1.576ArgAsp: 1.576 ± 1.553
7.092ArgGlu: 7.092 ± 1.824
1.576ArgPhe: 1.576 ± 0.645
4.728ArgGly: 4.728 ± 1.751
2.364ArgHis: 2.364 ± 1.187
1.576ArgIle: 1.576 ± 1.553
4.728ArgLys: 4.728 ± 0.534
3.94ArgLeu: 3.94 ± 1.297
2.364ArgMet: 2.364 ± 1.554
2.364ArgAsn: 2.364 ± 2.329
4.728ArgPro: 4.728 ± 0.857
0.788ArgGln: 0.788 ± 0.518
10.244ArgArg: 10.244 ± 4.925
7.092ArgSer: 7.092 ± 1.058
1.576ArgThr: 1.576 ± 0.803
5.516ArgVal: 5.516 ± 2.128
0.788ArgTrp: 0.788 ± 0.776
3.94ArgTyr: 3.94 ± 1.79
0.0ArgXaa: 0.0 ± 0.0
Ser
6.304SerAla: 6.304 ± 3.05
0.0SerCys: 0.0 ± 0.0
2.364SerAsp: 2.364 ± 0.842
7.092SerGlu: 7.092 ± 2.074
3.94SerPhe: 3.94 ± 2.59
3.94SerGly: 3.94 ± 1.464
1.576SerHis: 1.576 ± 0.645
2.364SerIle: 2.364 ± 0.311
5.516SerLys: 5.516 ± 0.826
5.516SerLeu: 5.516 ± 1.158
2.364SerMet: 2.364 ± 0.992
3.152SerAsn: 3.152 ± 2.401
2.364SerPro: 2.364 ± 0.842
0.0SerGln: 0.0 ± 0.0
4.728SerArg: 4.728 ± 1.293
5.516SerSer: 5.516 ± 1.437
5.516SerThr: 5.516 ± 1.904
3.94SerVal: 3.94 ± 1.941
1.576SerTrp: 1.576 ± 0.645
2.364SerTyr: 2.364 ± 1.187
0.0SerXaa: 0.0 ± 0.0
Thr
3.152ThrAla: 3.152 ± 0.705
0.0ThrCys: 0.0 ± 0.0
1.576ThrAsp: 1.576 ± 1.2
3.94ThrGlu: 3.94 ± 0.351
2.364ThrPhe: 2.364 ± 1.8
3.94ThrGly: 3.94 ± 2.227
0.788ThrHis: 0.788 ± 0.6
1.576ThrIle: 1.576 ± 0.803
5.516ThrLys: 5.516 ± 1.786
3.94ThrLeu: 3.94 ± 1.936
1.576ThrMet: 1.576 ± 0.516
0.788ThrAsn: 0.788 ± 0.6
3.94ThrPro: 3.94 ± 0.816
0.0ThrGln: 0.0 ± 0.0
3.152ThrArg: 3.152 ± 0.705
5.516ThrSer: 5.516 ± 2.541
3.152ThrThr: 3.152 ± 1.7
3.152ThrVal: 3.152 ± 1.064
2.364ThrTrp: 2.364 ± 1.187
1.576ThrTyr: 1.576 ± 0.516
0.0ThrXaa: 0.0 ± 0.0
Val
5.516ValAla: 5.516 ± 1.904
0.0ValCys: 0.0 ± 0.0
3.94ValAsp: 3.94 ± 2.845
1.576ValGlu: 1.576 ± 1.036
4.728ValPhe: 4.728 ± 1.684
9.456ValGly: 9.456 ± 2.392
0.788ValHis: 0.788 ± 0.6
3.152ValIle: 3.152 ± 1.29
3.152ValLys: 3.152 ± 2.072
7.092ValLeu: 7.092 ± 1.376
1.576ValMet: 1.576 ± 0.707
3.152ValAsn: 3.152 ± 0.705
1.576ValPro: 1.576 ± 0.803
1.576ValGln: 1.576 ± 1.2
6.304ValArg: 6.304 ± 2.537
8.668ValSer: 8.668 ± 2.424
3.94ValThr: 3.94 ± 2.227
3.94ValVal: 3.94 ± 1.837
1.576ValTrp: 1.576 ± 1.2
1.576ValTyr: 1.576 ± 1.036
0.0ValXaa: 0.0 ± 0.0
Trp
0.788TrpAla: 0.788 ± 0.776
0.0TrpCys: 0.0 ± 0.0
2.364TrpAsp: 2.364 ± 0.875
1.576TrpGlu: 1.576 ± 0.645
0.788TrpPhe: 0.788 ± 0.518
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
3.94TrpIle: 3.94 ± 1.272
0.788TrpLys: 0.788 ± 0.6
3.152TrpLeu: 3.152 ± 0.705
0.788TrpMet: 0.788 ± 0.6
0.788TrpAsn: 0.788 ± 0.776
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.788TrpThr: 0.788 ± 0.518
1.576TrpVal: 1.576 ± 0.803
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.152TyrAla: 3.152 ± 0.705
0.788TyrCys: 0.788 ± 0.6
3.94TyrAsp: 3.94 ± 2.141
2.364TyrGlu: 2.364 ± 0.992
1.576TyrPhe: 1.576 ± 0.516
1.576TyrGly: 1.576 ± 0.516
0.0TyrHis: 0.0 ± 0.0
1.576TyrIle: 1.576 ± 1.036
2.364TyrLys: 2.364 ± 1.554
1.576TyrLeu: 1.576 ± 0.516
0.788TyrMet: 0.788 ± 0.6
0.788TyrAsn: 0.788 ± 0.518
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
3.94TyrArg: 3.94 ± 2.59
3.94TyrSer: 3.94 ± 1.754
0.0TyrThr: 0.0 ± 0.0
1.576TyrVal: 1.576 ± 0.645
0.788TyrTrp: 0.788 ± 0.776
3.94TyrTyr: 3.94 ± 2.59
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1270 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski