Amino acid dipepetide frequency for Desertihabitans brevis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.496AlaAla: 19.496 ± 0.212
0.925AlaCys: 0.925 ± 0.028
8.858AlaAsp: 8.858 ± 0.117
9.586AlaGlu: 9.586 ± 0.109
3.222AlaPhe: 3.222 ± 0.051
13.033AlaGly: 13.033 ± 0.11
2.246AlaHis: 2.246 ± 0.045
3.231AlaIle: 3.231 ± 0.06
1.618AlaLys: 1.618 ± 0.04
13.808AlaLeu: 13.808 ± 0.141
2.522AlaMet: 2.522 ± 0.052
1.763AlaAsn: 1.763 ± 0.045
6.635AlaPro: 6.635 ± 0.104
3.344AlaGln: 3.344 ± 0.06
9.857AlaArg: 9.857 ± 0.125
6.188AlaSer: 6.188 ± 0.099
7.39AlaThr: 7.39 ± 0.099
12.733AlaVal: 12.733 ± 0.131
1.891AlaTrp: 1.891 ± 0.039
2.038AlaTyr: 2.038 ± 0.04
0.0AlaXaa: 0.0 ± 0.0
Cys
0.847CysAla: 0.847 ± 0.029
0.089CysCys: 0.089 ± 0.009
0.46CysAsp: 0.46 ± 0.021
0.419CysGlu: 0.419 ± 0.023
0.211CysPhe: 0.211 ± 0.014
0.807CysGly: 0.807 ± 0.028
0.194CysHis: 0.194 ± 0.015
0.145CysIle: 0.145 ± 0.011
0.054CysLys: 0.054 ± 0.007
0.661CysLeu: 0.661 ± 0.023
0.076CysMet: 0.076 ± 0.008
0.095CysAsn: 0.095 ± 0.01
0.49CysPro: 0.49 ± 0.022
0.194CysGln: 0.194 ± 0.013
0.6CysArg: 0.6 ± 0.023
0.409CysSer: 0.409 ± 0.017
0.511CysThr: 0.511 ± 0.027
0.572CysVal: 0.572 ± 0.021
0.125CysTrp: 0.125 ± 0.011
0.151CysTyr: 0.151 ± 0.011
0.0CysXaa: 0.0 ± 0.0
Asp
7.947AspAla: 7.947 ± 0.104
0.35AspCys: 0.35 ± 0.018
4.214AspAsp: 4.214 ± 0.08
4.048AspGlu: 4.048 ± 0.057
1.498AspPhe: 1.498 ± 0.039
6.621AspGly: 6.621 ± 0.108
1.388AspHis: 1.388 ± 0.036
1.544AspIle: 1.544 ± 0.039
0.695AspLys: 0.695 ± 0.027
6.855AspLeu: 6.855 ± 0.084
0.653AspMet: 0.653 ± 0.025
0.774AspAsn: 0.774 ± 0.03
5.288AspPro: 5.288 ± 0.084
1.741AspGln: 1.741 ± 0.041
4.993AspArg: 4.993 ± 0.074
2.166AspSer: 2.166 ± 0.051
2.921AspThr: 2.921 ± 0.049
6.146AspVal: 6.146 ± 0.08
1.005AspTrp: 1.005 ± 0.03
1.165AspTyr: 1.165 ± 0.035
0.0AspXaa: 0.0 ± 0.0
Glu
7.622GluAla: 7.622 ± 0.087
0.286GluCys: 0.286 ± 0.017
3.217GluAsp: 3.217 ± 0.061
3.795GluGlu: 3.795 ± 0.066
1.311GluPhe: 1.311 ± 0.033
4.347GluGly: 4.347 ± 0.066
1.829GluHis: 1.829 ± 0.042
1.879GluIle: 1.879 ± 0.041
0.878GluLys: 0.878 ± 0.03
7.435GluLeu: 7.435 ± 0.077
0.867GluMet: 0.867 ± 0.027
0.849GluAsn: 0.849 ± 0.03
3.807GluPro: 3.807 ± 0.063
3.097GluGln: 3.097 ± 0.065
5.761GluArg: 5.761 ± 0.077
2.178GluSer: 2.178 ± 0.038
2.794GluThr: 2.794 ± 0.054
6.098GluVal: 6.098 ± 0.088
0.805GluTrp: 0.805 ± 0.028
0.92GluTyr: 0.92 ± 0.032
0.0GluXaa: 0.0 ± 0.0
Phe
3.585PheAla: 3.585 ± 0.058
0.259PheCys: 0.259 ± 0.015
1.992PheAsp: 1.992 ± 0.04
1.435PheGlu: 1.435 ± 0.035
0.857PhePhe: 0.857 ± 0.033
2.793PheGly: 2.793 ± 0.049
0.515PheHis: 0.515 ± 0.02
0.71PheIle: 0.71 ± 0.026
0.34PheLys: 0.34 ± 0.019
2.545PheLeu: 2.545 ± 0.047
0.339PheMet: 0.339 ± 0.018
0.55PheAsn: 0.55 ± 0.026
1.291PhePro: 1.291 ± 0.027
0.683PheGln: 0.683 ± 0.024
1.637PheArg: 1.637 ± 0.039
1.502PheSer: 1.502 ± 0.039
1.898PheThr: 1.898 ± 0.042
2.445PheVal: 2.445 ± 0.048
0.468PheTrp: 0.468 ± 0.021
0.578PheTyr: 0.578 ± 0.02
0.0PheXaa: 0.0 ± 0.0
Gly
10.565GlyAla: 10.565 ± 0.129
0.814GlyCys: 0.814 ± 0.03
4.977GlyAsp: 4.977 ± 0.085
5.499GlyGlu: 5.499 ± 0.084
2.772GlyPhe: 2.772 ± 0.057
8.237GlyGly: 8.237 ± 0.115
2.065GlyHis: 2.065 ± 0.04
3.079GlyIle: 3.079 ± 0.055
1.402GlyLys: 1.402 ± 0.046
10.001GlyLeu: 10.001 ± 0.125
1.914GlyMet: 1.914 ± 0.041
1.448GlyAsn: 1.448 ± 0.043
5.281GlyPro: 5.281 ± 0.08
2.855GlyGln: 2.855 ± 0.052
8.257GlyArg: 8.257 ± 0.098
5.49GlySer: 5.49 ± 0.077
6.046GlyThr: 6.046 ± 0.088
8.254GlyVal: 8.254 ± 0.093
2.149GlyTrp: 2.149 ± 0.045
2.323GlyTyr: 2.323 ± 0.049
0.0GlyXaa: 0.0 ± 0.0
His
2.326HisAla: 2.326 ± 0.048
0.185HisCys: 0.185 ± 0.013
1.334HisAsp: 1.334 ± 0.039
1.136HisGlu: 1.136 ± 0.032
0.517HisPhe: 0.517 ± 0.022
2.149HisGly: 2.149 ± 0.046
0.73HisHis: 0.73 ± 0.024
0.478HisIle: 0.478 ± 0.02
0.192HisLys: 0.192 ± 0.014
2.633HisLeu: 2.633 ± 0.052
0.214HisMet: 0.214 ± 0.013
0.311HisAsn: 0.311 ± 0.016
1.938HisPro: 1.938 ± 0.039
0.646HisGln: 0.646 ± 0.023
2.285HisArg: 2.285 ± 0.044
0.854HisSer: 0.854 ± 0.027
1.139HisThr: 1.139 ± 0.033
1.745HisVal: 1.745 ± 0.039
0.363HisTrp: 0.363 ± 0.019
0.407HisTyr: 0.407 ± 0.02
0.0HisXaa: 0.0 ± 0.0
Ile
3.892IleAla: 3.892 ± 0.065
0.233IleCys: 0.233 ± 0.014
2.11IleAsp: 2.11 ± 0.048
1.775IleGlu: 1.775 ± 0.045
0.729IlePhe: 0.729 ± 0.031
3.232IleGly: 3.232 ± 0.056
0.463IleHis: 0.463 ± 0.021
0.916IleIle: 0.916 ± 0.032
0.458IleLys: 0.458 ± 0.022
1.851IleLeu: 1.851 ± 0.046
0.374IleMet: 0.374 ± 0.02
0.671IleAsn: 0.671 ± 0.022
1.489IlePro: 1.489 ± 0.036
0.657IleGln: 0.657 ± 0.021
1.969IleArg: 1.969 ± 0.049
1.636IleSer: 1.636 ± 0.038
2.151IleThr: 2.151 ± 0.046
2.223IleVal: 2.223 ± 0.049
0.368IleTrp: 0.368 ± 0.015
0.532IleTyr: 0.532 ± 0.023
0.0IleXaa: 0.0 ± 0.0
Lys
1.593LysAla: 1.593 ± 0.043
0.069LysCys: 0.069 ± 0.007
0.699LysAsp: 0.699 ± 0.027
0.67LysGlu: 0.67 ± 0.025
0.306LysPhe: 0.306 ± 0.015
1.137LysGly: 1.137 ± 0.038
0.318LysHis: 0.318 ± 0.014
0.533LysIle: 0.533 ± 0.025
0.435LysLys: 0.435 ± 0.027
1.145LysLeu: 1.145 ± 0.035
0.261LysMet: 0.261 ± 0.016
0.285LysAsn: 0.285 ± 0.016
0.765LysPro: 0.765 ± 0.026
0.47LysGln: 0.47 ± 0.022
0.954LysArg: 0.954 ± 0.033
0.726LysSer: 0.726 ± 0.026
0.834LysThr: 0.834 ± 0.031
1.344LysVal: 1.344 ± 0.044
0.136LysTrp: 0.136 ± 0.01
0.259LysTyr: 0.259 ± 0.015
0.0LysXaa: 0.0 ± 0.0
Leu
15.567LeuAla: 15.567 ± 0.143
0.714LeuCys: 0.714 ± 0.022
7.176LeuAsp: 7.176 ± 0.079
5.683LeuGlu: 5.683 ± 0.073
2.525LeuPhe: 2.525 ± 0.053
10.027LeuGly: 10.027 ± 0.119
2.227LeuHis: 2.227 ± 0.045
2.448LeuIle: 2.448 ± 0.047
1.185LeuLys: 1.185 ± 0.034
12.003LeuLeu: 12.003 ± 0.152
1.495LeuMet: 1.495 ± 0.039
1.489LeuAsn: 1.489 ± 0.033
6.286LeuPro: 6.286 ± 0.084
3.009LeuGln: 3.009 ± 0.057
8.69LeuArg: 8.69 ± 0.085
5.519LeuSer: 5.519 ± 0.076
7.021LeuThr: 7.021 ± 0.082
11.304LeuVal: 11.304 ± 0.129
1.412LeuTrp: 1.412 ± 0.037
1.596LeuTyr: 1.596 ± 0.04
0.0LeuXaa: 0.0 ± 0.0
Met
2.233MetAla: 2.233 ± 0.043
0.105MetCys: 0.105 ± 0.01
0.775MetAsp: 0.775 ± 0.025
0.699MetGlu: 0.699 ± 0.025
0.41MetPhe: 0.41 ± 0.019
1.259MetGly: 1.259 ± 0.031
0.308MetHis: 0.308 ± 0.017
0.547MetIle: 0.547 ± 0.02
0.294MetLys: 0.294 ± 0.016
1.652MetLeu: 1.652 ± 0.042
0.297MetMet: 0.297 ± 0.017
0.308MetAsn: 0.308 ± 0.015
1.027MetPro: 1.027 ± 0.027
0.467MetGln: 0.467 ± 0.023
1.233MetArg: 1.233 ± 0.035
1.312MetSer: 1.312 ± 0.034
1.485MetThr: 1.485 ± 0.032
1.559MetVal: 1.559 ± 0.037
0.165MetTrp: 0.165 ± 0.012
0.265MetTyr: 0.265 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
1.913AsnAla: 1.913 ± 0.043
0.111AsnCys: 0.111 ± 0.012
0.819AsnAsp: 0.819 ± 0.029
0.729AsnGlu: 0.729 ± 0.028
0.495AsnPhe: 0.495 ± 0.024
1.489AsnGly: 1.489 ± 0.041
0.336AsnHis: 0.336 ± 0.017
0.506AsnIle: 0.506 ± 0.021
0.238AsnLys: 0.238 ± 0.015
1.652AsnLeu: 1.652 ± 0.036
0.211AsnMet: 0.211 ± 0.013
0.367AsnAsn: 0.367 ± 0.018
1.326AsnPro: 1.326 ± 0.039
0.52AsnGln: 0.52 ± 0.022
1.113AsnArg: 1.113 ± 0.034
0.695AsnSer: 0.695 ± 0.025
0.959AsnThr: 0.959 ± 0.042
1.353AsnVal: 1.353 ± 0.038
0.246AsnTrp: 0.246 ± 0.013
0.37AsnTyr: 0.37 ± 0.019
0.0AsnXaa: 0.0 ± 0.0
Pro
8.438ProAla: 8.438 ± 0.108
0.318ProCys: 0.318 ± 0.017
4.875ProAsp: 4.875 ± 0.068
4.419ProGlu: 4.419 ± 0.067
1.54ProPhe: 1.54 ± 0.039
6.735ProGly: 6.735 ± 0.103
1.273ProHis: 1.273 ± 0.035
1.25ProIle: 1.25 ± 0.035
0.676ProLys: 0.676 ± 0.028
5.472ProLeu: 5.472 ± 0.065
0.91ProMet: 0.91 ± 0.028
0.798ProAsn: 0.798 ± 0.026
3.506ProPro: 3.506 ± 0.075
1.766ProGln: 1.766 ± 0.046
4.296ProArg: 4.296 ± 0.063
3.36ProSer: 3.36 ± 0.064
3.921ProThr: 3.921 ± 0.088
5.972ProVal: 5.972 ± 0.081
1.028ProTrp: 1.028 ± 0.029
1.085ProTyr: 1.085 ± 0.03
0.0ProXaa: 0.0 ± 0.0
Gln
3.699GlnAla: 3.699 ± 0.058
0.157GlnCys: 0.157 ± 0.011
1.195GlnAsp: 1.195 ± 0.033
1.386GlnGlu: 1.386 ± 0.035
0.727GlnPhe: 0.727 ± 0.025
2.318GlnGly: 2.318 ± 0.047
0.812GlnHis: 0.812 ± 0.025
1.076GlnIle: 1.076 ± 0.037
0.423GlnLys: 0.423 ± 0.022
3.766GlnLeu: 3.766 ± 0.061
0.521GlnMet: 0.521 ± 0.021
0.475GlnAsn: 0.475 ± 0.02
2.024GlnPro: 2.024 ± 0.049
1.574GlnGln: 1.574 ± 0.047
2.927GlnArg: 2.927 ± 0.056
1.305GlnSer: 1.305 ± 0.037
1.714GlnThr: 1.714 ± 0.039
3.134GlnVal: 3.134 ± 0.053
0.473GlnTrp: 0.473 ± 0.021
0.535GlnTyr: 0.535 ± 0.024
0.0GlnXaa: 0.0 ± 0.0
Arg
9.758ArgAla: 9.758 ± 0.119
0.616ArgCys: 0.616 ± 0.022
4.205ArgAsp: 4.205 ± 0.071
4.548ArgGlu: 4.548 ± 0.067
2.352ArgPhe: 2.352 ± 0.047
6.174ArgGly: 6.174 ± 0.087
2.056ArgHis: 2.056 ± 0.047
2.655ArgIle: 2.655 ± 0.044
0.988ArgLys: 0.988 ± 0.033
9.145ArgLeu: 9.145 ± 0.117
1.781ArgMet: 1.781 ± 0.038
1.164ArgAsn: 1.164 ± 0.033
5.477ArgPro: 5.477 ± 0.083
2.519ArgGln: 2.519 ± 0.051
9.094ArgArg: 9.094 ± 0.128
4.455ArgSer: 4.455 ± 0.062
5.232ArgThr: 5.232 ± 0.069
7.058ArgVal: 7.058 ± 0.081
1.795ArgTrp: 1.795 ± 0.042
1.703ArgTyr: 1.703 ± 0.035
0.0ArgXaa: 0.0 ± 0.0
Ser
6.28SerAla: 6.28 ± 0.1
0.364SerCys: 0.364 ± 0.016
2.791SerAsp: 2.791 ± 0.064
2.608SerGlu: 2.608 ± 0.046
1.53SerPhe: 1.53 ± 0.037
5.565SerGly: 5.565 ± 0.084
0.939SerHis: 0.939 ± 0.032
1.514SerIle: 1.514 ± 0.034
0.709SerLys: 0.709 ± 0.025
4.747SerLeu: 4.747 ± 0.064
1.057SerMet: 1.057 ± 0.026
0.835SerAsn: 0.835 ± 0.026
3.144SerPro: 3.144 ± 0.06
1.379SerGln: 1.379 ± 0.032
4.036SerArg: 4.036 ± 0.061
3.114SerSer: 3.114 ± 0.065
3.562SerThr: 3.562 ± 0.055
4.487SerVal: 4.487 ± 0.063
1.092SerTrp: 1.092 ± 0.03
1.168SerTyr: 1.168 ± 0.03
0.0SerXaa: 0.0 ± 0.0
Thr
8.092ThrAla: 8.092 ± 0.105
0.429ThrCys: 0.429 ± 0.022
3.899ThrAsp: 3.899 ± 0.069
3.492ThrGlu: 3.492 ± 0.058
1.809ThrPhe: 1.809 ± 0.046
6.431ThrGly: 6.431 ± 0.077
1.034ThrHis: 1.034 ± 0.031
1.946ThrIle: 1.946 ± 0.045
0.803ThrLys: 0.803 ± 0.028
6.13ThrLeu: 6.13 ± 0.091
0.948ThrMet: 0.948 ± 0.028
1.003ThrAsn: 1.003 ± 0.037
4.187ThrPro: 4.187 ± 0.077
1.376ThrGln: 1.376 ± 0.039
4.276ThrArg: 4.276 ± 0.067
3.487ThrSer: 3.487 ± 0.056
4.178ThrThr: 4.178 ± 0.064
6.303ThrVal: 6.303 ± 0.088
0.915ThrTrp: 0.915 ± 0.026
1.142ThrTyr: 1.142 ± 0.046
0.0ThrXaa: 0.0 ± 0.0
Val
12.569ValAla: 12.569 ± 0.118
0.774ValCys: 0.774 ± 0.032
6.344ValAsp: 6.344 ± 0.076
6.169ValGlu: 6.169 ± 0.076
2.464ValPhe: 2.464 ± 0.054
8.188ValGly: 8.188 ± 0.087
2.064ValHis: 2.064 ± 0.041
2.378ValIle: 2.378 ± 0.053
1.108ValLys: 1.108 ± 0.036
11.76ValLeu: 11.76 ± 0.134
1.441ValMet: 1.441 ± 0.04
1.537ValAsn: 1.537 ± 0.039
5.724ValPro: 5.724 ± 0.076
2.608ValGln: 2.608 ± 0.047
7.504ValArg: 7.504 ± 0.083
4.538ValSer: 4.538 ± 0.06
5.92ValThr: 5.92 ± 0.111
11.37ValVal: 11.37 ± 0.138
1.245ValTrp: 1.245 ± 0.031
1.418ValTyr: 1.418 ± 0.038
0.0ValXaa: 0.0 ± 0.0
Trp
1.705TrpAla: 1.705 ± 0.041
0.162TrpCys: 0.162 ± 0.013
0.86TrpAsp: 0.86 ± 0.026
0.749TrpGlu: 0.749 ± 0.028
0.542TrpPhe: 0.542 ± 0.021
1.089TrpGly: 1.089 ± 0.032
0.389TrpHis: 0.389 ± 0.018
0.472TrpIle: 0.472 ± 0.019
0.204TrpLys: 0.204 ± 0.014
1.963TrpLeu: 1.963 ± 0.046
0.327TrpMet: 0.327 ± 0.017
0.36TrpAsn: 0.36 ± 0.018
0.922TrpPro: 0.922 ± 0.028
0.704TrpGln: 0.704 ± 0.024
1.561TrpArg: 1.561 ± 0.036
1.08TrpSer: 1.08 ± 0.034
1.069TrpThr: 1.069 ± 0.035
1.515TrpVal: 1.515 ± 0.037
0.429TrpTrp: 0.429 ± 0.02
0.319TrpTyr: 0.319 ± 0.017
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.259TyrAla: 2.259 ± 0.039
0.153TyrCys: 0.153 ± 0.012
1.211TyrAsp: 1.211 ± 0.039
0.934TyrGlu: 0.934 ± 0.033
0.605TyrPhe: 0.605 ± 0.021
1.798TyrGly: 1.798 ± 0.047
0.397TyrHis: 0.397 ± 0.019
0.418TyrIle: 0.418 ± 0.019
0.238TyrLys: 0.238 ± 0.015
2.149TyrLeu: 2.149 ± 0.044
0.192TyrMet: 0.192 ± 0.013
0.367TyrAsn: 0.367 ± 0.02
1.033TyrPro: 1.033 ± 0.028
0.634TyrGln: 0.634 ± 0.022
1.728TyrArg: 1.728 ± 0.036
0.908TyrSer: 0.908 ± 0.033
1.134TyrThr: 1.134 ± 0.043
1.505TyrVal: 1.505 ± 0.038
0.311TyrTrp: 0.311 ± 0.018
0.428TyrTyr: 0.428 ± 0.021
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3682 proteins (1212445 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski