Amino acid dipepetide frequency for Cassava virus C

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.289AlaAla: 7.289 ± 3.582
3.644AlaCys: 3.644 ± 1.978
2.915AlaAsp: 2.915 ± 1.433
2.187AlaGlu: 2.187 ± 0.908
5.102AlaPhe: 5.102 ± 0.624
4.373AlaGly: 4.373 ± 1.474
2.187AlaHis: 2.187 ± 1.614
4.373AlaIle: 4.373 ± 0.949
3.644AlaLys: 3.644 ± 1.346
8.017AlaLeu: 8.017 ± 2.256
0.729AlaMet: 0.729 ± 0.396
0.729AlaAsn: 0.729 ± 1.168
2.915AlaPro: 2.915 ± 1.012
1.458AlaGln: 1.458 ± 0.716
8.746AlaArg: 8.746 ± 0.617
4.373AlaSer: 4.373 ± 1.491
2.187AlaThr: 2.187 ± 0.908
2.915AlaVal: 2.915 ± 0.861
1.458AlaTrp: 1.458 ± 0.968
0.729AlaTyr: 0.729 ± 1.168
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.729CysAsp: 0.729 ± 0.396
0.0CysGlu: 0.0 ± 0.0
0.729CysPhe: 0.729 ± 0.932
2.187CysGly: 2.187 ± 1.187
0.0CysHis: 0.0 ± 0.0
0.729CysIle: 0.729 ± 0.396
0.729CysLys: 0.729 ± 0.396
5.831CysLeu: 5.831 ± 1.556
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.729CysPro: 0.729 ± 0.396
1.458CysGln: 1.458 ± 0.716
0.729CysArg: 0.729 ± 0.396
2.187CysSer: 2.187 ± 0.686
0.729CysThr: 0.729 ± 0.396
0.729CysVal: 0.729 ± 0.396
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.915AspAla: 2.915 ± 0.861
2.187AspCys: 2.187 ± 0.686
2.915AspAsp: 2.915 ± 0.861
5.102AspGlu: 5.102 ± 0.624
1.458AspPhe: 1.458 ± 0.791
2.187AspGly: 2.187 ± 0.686
0.729AspHis: 0.729 ± 0.396
2.187AspIle: 2.187 ± 1.187
1.458AspLys: 1.458 ± 0.968
8.017AspLeu: 8.017 ± 3.483
1.458AspMet: 1.458 ± 0.716
2.187AspAsn: 2.187 ± 1.614
3.644AspPro: 3.644 ± 0.307
1.458AspGln: 1.458 ± 0.968
6.56AspArg: 6.56 ± 2.752
1.458AspSer: 1.458 ± 0.791
0.729AspThr: 0.729 ± 0.932
1.458AspVal: 1.458 ± 0.791
1.458AspTrp: 1.458 ± 0.968
1.458AspTyr: 1.458 ± 0.791
0.0AspXaa: 0.0 ± 0.0
Glu
2.187GluAla: 2.187 ± 1.614
0.729GluCys: 0.729 ± 0.396
0.729GluAsp: 0.729 ± 0.932
4.373GluGlu: 4.373 ± 1.373
2.915GluPhe: 2.915 ± 0.861
3.644GluGly: 3.644 ± 1.752
0.729GluHis: 0.729 ± 0.396
4.373GluIle: 4.373 ± 1.537
2.187GluLys: 2.187 ± 1.015
2.915GluLeu: 2.915 ± 1.012
0.0GluMet: 0.0 ± 0.0
2.915GluAsn: 2.915 ± 1.012
3.644GluPro: 3.644 ± 0.307
0.0GluGln: 0.0 ± 0.0
5.831GluArg: 5.831 ± 3.164
5.102GluSer: 5.102 ± 1.262
3.644GluThr: 3.644 ± 1.151
6.56GluVal: 6.56 ± 1.308
0.0GluTrp: 0.0 ± 0.0
1.458GluTyr: 1.458 ± 0.791
0.0GluXaa: 0.0 ± 0.0
Phe
2.187PheAla: 2.187 ± 0.686
1.458PheCys: 1.458 ± 0.716
2.915PheAsp: 2.915 ± 2.068
0.729PheGlu: 0.729 ± 1.168
2.915PhePhe: 2.915 ± 1.582
2.915PheGly: 2.915 ± 0.637
0.729PheHis: 0.729 ± 0.396
0.0PheIle: 0.0 ± 0.0
4.373PheLys: 4.373 ± 1.537
5.831PheLeu: 5.831 ± 2.225
0.0PheMet: 0.0 ± 0.0
0.729PheAsn: 0.729 ± 0.396
6.56PhePro: 6.56 ± 2.606
0.729PheGln: 0.729 ± 0.396
0.729PheArg: 0.729 ± 0.396
1.458PheSer: 1.458 ± 0.716
1.458PheThr: 1.458 ± 0.791
2.915PheVal: 2.915 ± 0.861
0.729PheTrp: 0.729 ± 0.396
1.458PheTyr: 1.458 ± 0.791
0.0PheXaa: 0.0 ± 0.0
Gly
2.915GlyAla: 2.915 ± 2.068
0.0GlyCys: 0.0 ± 0.0
5.831GlyAsp: 5.831 ± 3.164
5.102GlyGlu: 5.102 ± 4.072
1.458GlyPhe: 1.458 ± 0.791
8.746GlyGly: 8.746 ± 1.911
2.187GlyHis: 2.187 ± 0.686
2.915GlyIle: 2.915 ± 1.582
3.644GlyLys: 3.644 ± 1.978
5.831GlyLeu: 5.831 ± 2.024
0.729GlyMet: 0.729 ± 0.729
5.102GlyAsn: 5.102 ± 1.855
2.187GlyPro: 2.187 ± 0.908
2.915GlyGln: 2.915 ± 0.637
4.373GlyArg: 4.373 ± 0.949
3.644GlySer: 3.644 ± 1.346
6.56GlyThr: 6.56 ± 3.045
2.187GlyVal: 2.187 ± 0.908
2.187GlyTrp: 2.187 ± 0.908
2.187GlyTyr: 2.187 ± 1.015
0.0GlyXaa: 0.0 ± 0.0
His
0.729HisAla: 0.729 ± 1.168
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.458HisGlu: 1.458 ± 0.791
1.458HisPhe: 1.458 ± 0.791
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.458HisIle: 1.458 ± 0.791
0.729HisLys: 0.729 ± 0.396
2.187HisLeu: 2.187 ± 1.187
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.187HisPro: 2.187 ± 1.187
0.0HisGln: 0.0 ± 0.0
2.915HisArg: 2.915 ± 0.861
0.0HisSer: 0.0 ± 0.0
2.915HisThr: 2.915 ± 0.861
0.729HisVal: 0.729 ± 0.932
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
7.289IleAla: 7.289 ± 2.479
1.458IleCys: 1.458 ± 0.968
2.915IleAsp: 2.915 ± 1.433
2.187IleGlu: 2.187 ± 0.686
2.187IlePhe: 2.187 ± 0.908
1.458IleGly: 1.458 ± 0.968
0.729IleHis: 0.729 ± 0.396
0.729IleIle: 0.729 ± 0.932
3.644IleLys: 3.644 ± 0.307
5.102IleLeu: 5.102 ± 2.769
1.458IleMet: 1.458 ± 0.758
1.458IleAsn: 1.458 ± 0.716
2.187IlePro: 2.187 ± 1.015
0.729IleGln: 0.729 ± 0.396
1.458IleArg: 1.458 ± 0.968
4.373IleSer: 4.373 ± 1.373
3.644IleThr: 3.644 ± 0.307
2.915IleVal: 2.915 ± 0.861
2.915IleTrp: 2.915 ± 1.433
2.187IleTyr: 2.187 ± 1.187
0.0IleXaa: 0.0 ± 0.0
Lys
2.187LysAla: 2.187 ± 0.686
0.0LysCys: 0.0 ± 0.0
2.187LysAsp: 2.187 ± 0.908
2.187LysGlu: 2.187 ± 0.908
0.0LysPhe: 0.0 ± 0.0
4.373LysGly: 4.373 ± 1.474
2.187LysHis: 2.187 ± 0.908
3.644LysIle: 3.644 ± 0.307
2.915LysLys: 2.915 ± 2.537
8.017LysLeu: 8.017 ± 3.214
0.0LysMet: 0.0 ± 0.0
2.915LysAsn: 2.915 ± 0.861
2.915LysPro: 2.915 ± 1.012
1.458LysGln: 1.458 ± 0.791
2.915LysArg: 2.915 ± 1.582
1.458LysSer: 1.458 ± 0.791
1.458LysThr: 1.458 ± 0.968
2.187LysVal: 2.187 ± 1.015
0.729LysTrp: 0.729 ± 0.932
1.458LysTyr: 1.458 ± 0.791
0.0LysXaa: 0.0 ± 0.0
Leu
12.391LeuAla: 12.391 ± 1.862
2.915LeuCys: 2.915 ± 0.861
4.373LeuAsp: 4.373 ± 2.905
6.56LeuGlu: 6.56 ± 2.606
4.373LeuPhe: 4.373 ± 2.373
5.831LeuGly: 5.831 ± 0.438
0.729LeuHis: 0.729 ± 0.396
4.373LeuIle: 4.373 ± 1.491
5.831LeuLys: 5.831 ± 3.431
6.56LeuLeu: 6.56 ± 2.592
2.187LeuMet: 2.187 ± 0.686
2.187LeuAsn: 2.187 ± 0.908
10.204LeuPro: 10.204 ± 4.088
0.729LeuGln: 0.729 ± 0.932
6.56LeuArg: 6.56 ± 1.17
11.662LeuSer: 11.662 ± 2.036
2.187LeuThr: 2.187 ± 0.686
6.56LeuVal: 6.56 ± 1.17
0.729LeuTrp: 0.729 ± 0.396
2.187LeuTyr: 2.187 ± 0.686
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
1.458MetAsp: 1.458 ± 0.716
1.458MetGlu: 1.458 ± 0.716
0.0MetPhe: 0.0 ± 0.0
2.187MetGly: 2.187 ± 1.187
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.729MetLys: 0.729 ± 0.396
1.458MetLeu: 1.458 ± 0.716
0.0MetMet: 0.0 ± 0.0
0.729MetAsn: 0.729 ± 0.396
0.0MetPro: 0.0 ± 0.0
1.458MetGln: 1.458 ± 0.968
0.729MetArg: 0.729 ± 0.396
0.729MetSer: 0.729 ± 0.396
0.0MetThr: 0.0 ± 0.0
1.458MetVal: 1.458 ± 0.968
0.0MetTrp: 0.0 ± 0.0
0.729MetTyr: 0.729 ± 0.396
0.0MetXaa: 0.0 ± 0.0
Asn
2.187AsnAla: 2.187 ± 1.187
0.0AsnCys: 0.0 ± 0.0
1.458AsnAsp: 1.458 ± 0.716
1.458AsnGlu: 1.458 ± 0.716
0.729AsnPhe: 0.729 ± 0.396
3.644AsnGly: 3.644 ± 1.752
0.729AsnHis: 0.729 ± 0.396
1.458AsnIle: 1.458 ± 0.791
1.458AsnLys: 1.458 ± 0.968
4.373AsnLeu: 4.373 ± 1.373
0.729AsnMet: 0.729 ± 0.396
2.187AsnAsn: 2.187 ± 3.504
2.915AsnPro: 2.915 ± 2.068
1.458AsnGln: 1.458 ± 0.791
5.831AsnArg: 5.831 ± 1.274
2.187AsnSer: 2.187 ± 2.109
1.458AsnThr: 1.458 ± 1.864
1.458AsnVal: 1.458 ± 2.336
0.729AsnTrp: 0.729 ± 0.396
0.729AsnTyr: 0.729 ± 0.396
0.0AsnXaa: 0.0 ± 0.0
Pro
3.644ProAla: 3.644 ± 2.535
0.0ProCys: 0.0 ± 0.0
4.373ProAsp: 4.373 ± 1.373
4.373ProGlu: 4.373 ± 2.373
2.187ProPhe: 2.187 ± 0.686
4.373ProGly: 4.373 ± 1.474
0.729ProHis: 0.729 ± 0.396
5.831ProIle: 5.831 ± 1.723
0.729ProLys: 0.729 ± 1.168
2.915ProLeu: 2.915 ± 0.861
0.0ProMet: 0.0 ± 0.0
2.187ProAsn: 2.187 ± 0.686
3.644ProPro: 3.644 ± 3.067
3.644ProGln: 3.644 ± 0.307
5.831ProArg: 5.831 ± 2.729
5.102ProSer: 5.102 ± 1.855
4.373ProThr: 4.373 ± 0.949
9.475ProVal: 9.475 ± 2.849
1.458ProTrp: 1.458 ± 0.968
0.729ProTyr: 0.729 ± 0.396
0.0ProXaa: 0.0 ± 0.0
Gln
1.458GlnAla: 1.458 ± 1.403
0.0GlnCys: 0.0 ± 0.0
1.458GlnAsp: 1.458 ± 0.716
3.644GlnGlu: 3.644 ± 0.307
1.458GlnPhe: 1.458 ± 0.716
2.187GlnGly: 2.187 ± 0.908
0.0GlnHis: 0.0 ± 0.0
1.458GlnIle: 1.458 ± 0.968
0.0GlnLys: 0.0 ± 0.0
5.831GlnLeu: 5.831 ± 2.225
0.0GlnMet: 0.0 ± 0.0
0.729GlnAsn: 0.729 ± 1.168
2.187GlnPro: 2.187 ± 2.076
0.0GlnGln: 0.0 ± 0.0
1.458GlnArg: 1.458 ± 0.791
2.187GlnSer: 2.187 ± 1.187
1.458GlnThr: 1.458 ± 0.968
2.187GlnVal: 2.187 ± 0.908
1.458GlnTrp: 1.458 ± 0.968
2.187GlnTyr: 2.187 ± 0.686
0.0GlnXaa: 0.0 ± 0.0
Arg
3.644ArgAla: 3.644 ± 1.151
2.187ArgCys: 2.187 ± 1.187
2.915ArgAsp: 2.915 ± 2.537
3.644ArgGlu: 3.644 ± 1.978
3.644ArgPhe: 3.644 ± 1.978
8.017ArgGly: 8.017 ± 1.215
0.729ArgHis: 0.729 ± 0.396
4.373ArgIle: 4.373 ± 1.491
2.915ArgLys: 2.915 ± 1.582
5.102ArgLeu: 5.102 ± 1.855
1.458ArgMet: 1.458 ± 0.791
2.187ArgAsn: 2.187 ± 2.407
5.102ArgPro: 5.102 ± 0.64
5.102ArgGln: 5.102 ± 1.262
12.391ArgArg: 12.391 ± 3.613
9.475ArgSer: 9.475 ± 2.423
6.56ArgThr: 6.56 ± 1.17
6.56ArgVal: 6.56 ± 2.229
2.187ArgTrp: 2.187 ± 0.686
1.458ArgTyr: 1.458 ± 0.716
0.0ArgXaa: 0.0 ± 0.0
Ser
7.289SerAla: 7.289 ± 2.692
1.458SerCys: 1.458 ± 1.864
2.915SerAsp: 2.915 ± 1.582
0.0SerGlu: 0.0 ± 0.0
5.831SerPhe: 5.831 ± 1.151
5.102SerGly: 5.102 ± 2.629
0.729SerHis: 0.729 ± 0.396
4.373SerIle: 4.373 ± 2.03
4.373SerLys: 4.373 ± 1.537
5.102SerLeu: 5.102 ± 1.852
0.729SerMet: 0.729 ± 0.396
4.373SerAsn: 4.373 ± 4.218
7.289SerPro: 7.289 ± 2.303
4.373SerGln: 4.373 ± 1.537
3.644SerArg: 3.644 ± 0.307
10.204SerSer: 10.204 ± 1.793
5.102SerThr: 5.102 ± 3.027
5.102SerVal: 5.102 ± 0.64
1.458SerTrp: 1.458 ± 0.791
0.729SerTyr: 0.729 ± 0.932
0.0SerXaa: 0.0 ± 0.0
Thr
2.915ThrAla: 2.915 ± 0.861
1.458ThrCys: 1.458 ± 0.716
3.644ThrAsp: 3.644 ± 1.313
2.915ThrGlu: 2.915 ± 1.582
0.729ThrPhe: 0.729 ± 0.396
0.729ThrGly: 0.729 ± 0.396
1.458ThrHis: 1.458 ± 0.791
6.56ThrIle: 6.56 ± 2.363
2.187ThrLys: 2.187 ± 2.407
4.373ThrLeu: 4.373 ± 2.03
2.187ThrMet: 2.187 ± 0.986
0.729ThrAsn: 0.729 ± 0.396
1.458ThrPro: 1.458 ± 0.716
0.0ThrGln: 0.0 ± 0.0
9.475ThrArg: 9.475 ± 2.727
2.915ThrSer: 2.915 ± 1.433
2.187ThrThr: 2.187 ± 2.795
3.644ThrVal: 3.644 ± 0.307
0.729ThrTrp: 0.729 ± 0.396
2.915ThrTyr: 2.915 ± 1.433
0.0ThrXaa: 0.0 ± 0.0
Val
5.102ValAla: 5.102 ± 2.642
0.0ValCys: 0.0 ± 0.0
3.644ValAsp: 3.644 ± 1.346
5.831ValGlu: 5.831 ± 1.556
1.458ValPhe: 1.458 ± 0.968
5.102ValGly: 5.102 ± 0.624
1.458ValHis: 1.458 ± 0.791
0.729ValIle: 0.729 ± 1.168
2.915ValLys: 2.915 ± 1.582
9.475ValLeu: 9.475 ± 2.977
0.0ValMet: 0.0 ± 0.0
3.644ValAsn: 3.644 ± 1.151
5.102ValPro: 5.102 ± 0.624
2.187ValGln: 2.187 ± 2.109
3.644ValArg: 3.644 ± 0.307
6.56ValSer: 6.56 ± 1.841
4.373ValThr: 4.373 ± 1.373
5.102ValVal: 5.102 ± 1.855
0.0ValTrp: 0.0 ± 0.0
2.915ValTyr: 2.915 ± 1.937
0.0ValXaa: 0.0 ± 0.0
Trp
1.458TrpAla: 1.458 ± 0.791
0.0TrpCys: 0.0 ± 0.0
2.187TrpAsp: 2.187 ± 0.686
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.458TrpGly: 1.458 ± 0.791
0.729TrpHis: 0.729 ± 0.396
0.729TrpIle: 0.729 ± 0.932
0.729TrpLys: 0.729 ± 1.168
0.729TrpLeu: 0.729 ± 0.396
0.729TrpMet: 0.729 ± 0.396
0.729TrpAsn: 0.729 ± 0.396
0.729TrpPro: 0.729 ± 0.932
0.729TrpGln: 0.729 ± 0.396
1.458TrpArg: 1.458 ± 0.791
2.187TrpSer: 2.187 ± 0.908
1.458TrpThr: 1.458 ± 0.968
2.187TrpVal: 2.187 ± 2.407
0.729TrpTrp: 0.729 ± 0.396
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.187TyrAla: 2.187 ± 1.187
0.0TyrCys: 0.0 ± 0.0
1.458TyrAsp: 1.458 ± 0.791
0.729TyrGlu: 0.729 ± 0.932
2.187TyrPhe: 2.187 ± 0.908
2.187TyrGly: 2.187 ± 1.187
0.0TyrHis: 0.0 ± 0.0
1.458TyrIle: 1.458 ± 0.791
0.0TyrLys: 0.0 ± 0.0
1.458TyrLeu: 1.458 ± 0.791
0.0TyrMet: 0.0 ± 0.0
1.458TyrAsn: 1.458 ± 0.791
0.0TyrPro: 0.0 ± 0.0
1.458TyrGln: 1.458 ± 1.403
4.373TyrArg: 4.373 ± 0.949
2.915TyrSer: 2.915 ± 1.012
0.729TyrThr: 0.729 ± 0.932
2.915TyrVal: 2.915 ± 1.433
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1373 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski