Amino acid dipepetide frequency for Acidiluteibacter ferrifornacis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.624AlaAla: 4.624 ± 0.106	0.567AlaCys: 0.567 ± 0.019	3.507AlaAsp: 3.507 ± 0.092	4.041AlaGlu: 4.041 ± 0.082	3.297AlaPhe: 3.297 ± 0.066	3.98AlaGly: 3.98 ± 0.093	1.029AlaHis: 1.029 ± 0.033	5.775AlaIle: 5.775 ± 0.09	4.378AlaLys: 4.378 ± 0.088	5.884AlaLeu: 5.884 ± 0.1	1.453AlaMet: 1.453 ± 0.045	3.706AlaAsn: 3.706 ± 0.086	1.93AlaPro: 1.93 ± 0.048	2.458AlaGln: 2.458 ± 0.046	1.949AlaArg: 1.949 ± 0.044	4.094AlaSer: 4.094 ± 0.086	3.686AlaThr: 3.686 ± 0.105	3.959AlaVal: 3.959 ± 0.065	0.595AlaTrp: 0.595 ± 0.022	2.456AlaTyr: 2.456 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.456CysAla: 0.456 ± 0.022	0.119CysCys: 0.119 ± 0.011	0.503CysAsp: 0.503 ± 0.027	0.473CysGlu: 0.473 ± 0.023	0.46CysPhe: 0.46 ± 0.023	0.661CysGly: 0.661 ± 0.027	0.184CysHis: 0.184 ± 0.015	0.625CysIle: 0.625 ± 0.028	0.457CysLys: 0.457 ± 0.022	0.639CysLeu: 0.639 ± 0.026	0.13CysMet: 0.13 ± 0.01	0.478CysAsn: 0.478 ± 0.028	0.348CysPro: 0.348 ± 0.021	0.255CysGln: 0.255 ± 0.017	0.228CysArg: 0.228 ± 0.014	0.633CysSer: 0.633 ± 0.035	0.458CysThr: 0.458 ± 0.03	0.417CysVal: 0.417 ± 0.021	0.077CysTrp: 0.077 ± 0.01	0.327CysTyr: 0.327 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	3.403AspAla: 3.403 ± 0.092	0.462AspCys: 0.462 ± 0.025	2.544AspAsp: 2.544 ± 0.055	3.615AspGlu: 3.615 ± 0.08	3.448AspPhe: 3.448 ± 0.063	3.805AspGly: 3.805 ± 0.176	0.854AspHis: 0.854 ± 0.032	4.046AspIle: 4.046 ± 0.066	3.477AspLys: 3.477 ± 0.063	5.043AspLeu: 5.043 ± 0.077	1.002AspMet: 1.002 ± 0.031	2.813AspAsn: 2.813 ± 0.075	1.712AspPro: 1.712 ± 0.043	1.889AspGln: 1.889 ± 0.044	1.903AspArg: 1.903 ± 0.044	4.142AspSer: 4.142 ± 0.099	2.951AspThr: 2.951 ± 0.087	3.199AspVal: 3.199 ± 0.054	0.665AspTrp: 0.665 ± 0.025	2.744AspTyr: 2.744 ± 0.054	0.0AspXaa: 0.0 ± 0.0
Glu	4.043GluAla: 4.043 ± 0.081	0.356GluCys: 0.356 ± 0.02	3.104GluAsp: 3.104 ± 0.058	4.989GluGlu: 4.989 ± 0.095	2.926GluPhe: 2.926 ± 0.065	3.821GluGly: 3.821 ± 0.068	0.968GluHis: 0.968 ± 0.036	5.312GluIle: 5.312 ± 0.087	5.674GluLys: 5.674 ± 0.112	6.629GluLeu: 6.629 ± 0.106	1.635GluMet: 1.635 ± 0.042	4.169GluAsn: 4.169 ± 0.069	1.459GluPro: 1.459 ± 0.039	2.425GluGln: 2.425 ± 0.058	2.564GluArg: 2.564 ± 0.062	3.781GluSer: 3.781 ± 0.056	2.954GluThr: 2.954 ± 0.052	4.615GluVal: 4.615 ± 0.071	0.724GluTrp: 0.724 ± 0.027	2.527GluTyr: 2.527 ± 0.052	0.0GluXaa: 0.0 ± 0.0
Phe	2.993PheAla: 2.993 ± 0.059	0.467PheCys: 0.467 ± 0.022	3.118PheAsp: 3.118 ± 0.058	3.459PheGlu: 3.459 ± 0.067	2.639PhePhe: 2.639 ± 0.066	3.619PheGly: 3.619 ± 0.065	0.874PheHis: 0.874 ± 0.031	4.154PheIle: 4.154 ± 0.069	3.505PheLys: 3.505 ± 0.075	4.641PheLeu: 4.641 ± 0.087	1.051PheMet: 1.051 ± 0.037	3.453PheAsn: 3.453 ± 0.07	1.786PhePro: 1.786 ± 0.043	1.809PheGln: 1.809 ± 0.041	1.706PheArg: 1.706 ± 0.043	4.142PheSer: 4.142 ± 0.068	3.022PheThr: 3.022 ± 0.06	3.023PheVal: 3.023 ± 0.058	0.538PheTrp: 0.538 ± 0.025	2.366PheTyr: 2.366 ± 0.055	0.0PheXaa: 0.0 ± 0.0
Gly	4.256GlyAla: 4.256 ± 0.088	0.724GlyCys: 0.724 ± 0.057	3.38GlyAsp: 3.38 ± 0.07	3.746GlyGlu: 3.746 ± 0.072	3.55GlyPhe: 3.55 ± 0.063	4.573GlyGly: 4.573 ± 0.095	1.071GlyHis: 1.071 ± 0.032	5.445GlyIle: 5.445 ± 0.089	4.737GlyLys: 4.737 ± 0.081	5.757GlyLeu: 5.757 ± 0.08	1.601GlyMet: 1.601 ± 0.04	3.812GlyAsn: 3.812 ± 0.085	1.431GlyPro: 1.431 ± 0.046	2.035GlyGln: 2.035 ± 0.044	2.095GlyArg: 2.095 ± 0.055	4.375GlySer: 4.375 ± 0.109	3.931GlyThr: 3.931 ± 0.136	4.625GlyVal: 4.625 ± 0.075	0.728GlyTrp: 0.728 ± 0.026	2.732GlyTyr: 2.732 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	0.889HisAla: 0.889 ± 0.031	0.186HisCys: 0.186 ± 0.016	0.713HisAsp: 0.713 ± 0.026	0.911HisGlu: 0.911 ± 0.03	1.168HisPhe: 1.168 ± 0.037	0.928HisGly: 0.928 ± 0.036	0.484HisHis: 0.484 ± 0.026	1.304HisIle: 1.304 ± 0.034	0.981HisLys: 0.981 ± 0.034	1.879HisLeu: 1.879 ± 0.045	0.292HisMet: 0.292 ± 0.014	0.84HisAsn: 0.84 ± 0.03	0.872HisPro: 0.872 ± 0.03	0.858HisGln: 0.858 ± 0.032	0.655HisArg: 0.655 ± 0.027	1.172HisSer: 1.172 ± 0.038	0.896HisThr: 0.896 ± 0.031	0.79HisVal: 0.79 ± 0.028	0.19HisTrp: 0.19 ± 0.013	0.849HisTyr: 0.849 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.74IleAla: 5.74 ± 0.084	0.677IleCys: 0.677 ± 0.032	5.34IleAsp: 5.34 ± 0.073	5.856IleGlu: 5.856 ± 0.093	3.477IlePhe: 3.477 ± 0.067	5.486IleGly: 5.486 ± 0.078	1.476IleHis: 1.476 ± 0.049	6.101IleIle: 6.101 ± 0.093	5.579IleLys: 5.579 ± 0.096	6.813IleLeu: 6.813 ± 0.102	1.348IleMet: 1.348 ± 0.034	4.995IleAsn: 4.995 ± 0.075	3.172IlePro: 3.172 ± 0.058	3.009IleGln: 3.009 ± 0.061	2.736IleArg: 2.736 ± 0.055	6.213IleSer: 6.213 ± 0.084	4.598IleThr: 4.598 ± 0.096	5.058IleVal: 5.058 ± 0.079	0.65IleTrp: 0.65 ± 0.022	3.141IleTyr: 3.141 ± 0.064	0.0IleXaa: 0.0 ± 0.0
Lys	4.685LysAla: 4.685 ± 0.085	0.343LysCys: 0.343 ± 0.019	3.88LysAsp: 3.88 ± 0.081	5.813LysGlu: 5.813 ± 0.111	2.667LysPhe: 2.667 ± 0.058	4.627LysGly: 4.627 ± 0.072	1.206LysHis: 1.206 ± 0.036	5.326LysIle: 5.326 ± 0.087	6.003LysLys: 6.003 ± 0.104	6.112LysLeu: 6.112 ± 0.1	2.029LysMet: 2.029 ± 0.055	4.538LysAsn: 4.538 ± 0.074	2.132LysPro: 2.132 ± 0.049	2.558LysGln: 2.558 ± 0.055	2.823LysArg: 2.823 ± 0.061	4.829LysSer: 4.829 ± 0.081	3.882LysThr: 3.882 ± 0.071	5.037LysVal: 5.037 ± 0.074	0.79LysTrp: 0.79 ± 0.027	2.931LysTyr: 2.931 ± 0.058	0.0LysXaa: 0.0 ± 0.0
Leu	5.545LeuAla: 5.545 ± 0.097	0.654LeuCys: 0.654 ± 0.028	4.865LeuAsp: 4.865 ± 0.1	5.66LeuGlu: 5.66 ± 0.094	5.274LeuPhe: 5.274 ± 0.095	5.52LeuGly: 5.52 ± 0.077	1.413LeuHis: 1.413 ± 0.04	7.87LeuIle: 7.87 ± 0.1	7.502LeuLys: 7.502 ± 0.115	8.902LeuLeu: 8.902 ± 0.151	2.057LeuMet: 2.057 ± 0.053	5.945LeuAsn: 5.945 ± 0.084	3.469LeuPro: 3.469 ± 0.061	2.852LeuGln: 2.852 ± 0.06	3.002LeuArg: 3.002 ± 0.06	7.235LeuSer: 7.235 ± 0.101	5.107LeuThr: 5.107 ± 0.067	5.324LeuVal: 5.324 ± 0.078	0.849LeuTrp: 0.849 ± 0.037	3.251LeuTyr: 3.251 ± 0.065	0.0LeuXaa: 0.0 ± 0.0
Met	1.597MetAla: 1.597 ± 0.043	0.144MetCys: 0.144 ± 0.013	1.228MetAsp: 1.228 ± 0.038	1.451MetGlu: 1.451 ± 0.04	0.692MetPhe: 0.692 ± 0.023	1.476MetGly: 1.476 ± 0.039	0.393MetHis: 0.393 ± 0.019	1.578MetIle: 1.578 ± 0.044	2.155MetLys: 2.155 ± 0.047	1.746MetLeu: 1.746 ± 0.042	0.596MetMet: 0.596 ± 0.029	1.35MetAsn: 1.35 ± 0.039	0.802MetPro: 0.802 ± 0.024	0.762MetGln: 0.762 ± 0.027	0.872MetArg: 0.872 ± 0.03	1.424MetSer: 1.424 ± 0.042	1.092MetThr: 1.092 ± 0.033	1.389MetVal: 1.389 ± 0.044	0.162MetTrp: 0.162 ± 0.012	0.665MetTyr: 0.665 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.588AsnAla: 3.588 ± 0.067	0.567AsnCys: 0.567 ± 0.028	3.103AsnAsp: 3.103 ± 0.083	3.75AsnGlu: 3.75 ± 0.067	3.081AsnPhe: 3.081 ± 0.057	4.702AsnGly: 4.702 ± 0.123	1.151AsnHis: 1.151 ± 0.029	4.305AsnIle: 4.305 ± 0.074	4.004AsnLys: 4.004 ± 0.07	5.303AsnLeu: 5.303 ± 0.077	1.075AsnMet: 1.075 ± 0.032	4.001AsnAsn: 4.001 ± 0.093	2.815AsnPro: 2.815 ± 0.079	2.849AsnGln: 2.849 ± 0.059	2.421AsnArg: 2.421 ± 0.049	4.491AsnSer: 4.491 ± 0.088	3.574AsnThr: 3.574 ± 0.085	3.399AsnVal: 3.399 ± 0.064	0.814AsnTrp: 0.814 ± 0.028	3.169AsnTyr: 3.169 ± 0.058	0.0AsnXaa: 0.0 ± 0.0
Pro	1.937ProAla: 1.937 ± 0.04	0.267ProCys: 0.267 ± 0.02	1.884ProAsp: 1.884 ± 0.044	2.396ProGlu: 2.396 ± 0.052	2.108ProPhe: 2.108 ± 0.059	1.783ProGly: 1.783 ± 0.048	0.61ProHis: 0.61 ± 0.024	3.208ProIle: 3.208 ± 0.063	2.258ProLys: 2.258 ± 0.048	2.927ProLeu: 2.927 ± 0.055	0.755ProMet: 0.755 ± 0.027	2.446ProAsn: 2.446 ± 0.06	0.948ProPro: 0.948 ± 0.04	1.095ProGln: 1.095 ± 0.034	0.902ProArg: 0.902 ± 0.031	2.533ProSer: 2.533 ± 0.061	2.253ProThr: 2.253 ± 0.074	2.043ProVal: 2.043 ± 0.048	0.295ProTrp: 0.295 ± 0.017	1.401ProTyr: 1.401 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	1.937GlnAla: 1.937 ± 0.039	0.2GlnCys: 0.2 ± 0.014	1.459GlnAsp: 1.459 ± 0.039	2.337GlnGlu: 2.337 ± 0.054	2.06GlnPhe: 2.06 ± 0.041	1.681GlnGly: 1.681 ± 0.046	0.603GlnHis: 0.603 ± 0.026	2.781GlnIle: 2.781 ± 0.057	2.683GlnLys: 2.683 ± 0.058	4.288GlnLeu: 4.288 ± 0.085	0.886GlnMet: 0.886 ± 0.035	2.061GlnAsn: 2.061 ± 0.046	1.205GlnPro: 1.205 ± 0.04	1.497GlnGln: 1.497 ± 0.05	1.28GlnArg: 1.28 ± 0.04	2.401GlnSer: 2.401 ± 0.042	2.017GlnThr: 2.017 ± 0.048	2.067GlnVal: 2.067 ± 0.041	0.394GlnTrp: 0.394 ± 0.02	1.422GlnTyr: 1.422 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	1.998ArgAla: 1.998 ± 0.046	0.207ArgCys: 0.207 ± 0.014	1.653ArgAsp: 1.653 ± 0.049	2.063ArgGlu: 2.063 ± 0.049	1.954ArgPhe: 1.954 ± 0.037	1.902ArgGly: 1.902 ± 0.041	0.54ArgHis: 0.54 ± 0.02	3.157ArgIle: 3.157 ± 0.061	2.758ArgLys: 2.758 ± 0.064	3.457ArgLeu: 3.457 ± 0.058	0.965ArgMet: 0.965 ± 0.029	2.16ArgAsn: 2.16 ± 0.045	1.12ArgPro: 1.12 ± 0.035	1.042ArgGln: 1.042 ± 0.034	1.279ArgArg: 1.279 ± 0.036	2.177ArgSer: 2.177 ± 0.04	1.836ArgThr: 1.836 ± 0.041	2.089ArgVal: 2.089 ± 0.048	0.382ArgTrp: 0.382 ± 0.022	1.493ArgTyr: 1.493 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.459SerAla: 4.459 ± 0.086	0.656SerCys: 0.656 ± 0.038	3.651SerAsp: 3.651 ± 0.07	4.045SerGlu: 4.045 ± 0.072	4.158SerPhe: 4.158 ± 0.069	4.935SerGly: 4.935 ± 0.108	1.049SerHis: 1.049 ± 0.031	6.715SerIle: 6.715 ± 0.086	4.817SerLys: 4.817 ± 0.09	6.475SerLeu: 6.475 ± 0.087	1.418SerMet: 1.418 ± 0.034	4.759SerAsn: 4.759 ± 0.103	2.513SerPro: 2.513 ± 0.07	2.207SerGln: 2.207 ± 0.049	2.161SerArg: 2.161 ± 0.044	5.284SerSer: 5.284 ± 0.121	4.421SerThr: 4.421 ± 0.101	4.154SerVal: 4.154 ± 0.083	0.777SerTrp: 0.777 ± 0.03	3.068SerTyr: 3.068 ± 0.071	0.0SerXaa: 0.0 ± 0.0
Thr	4.021ThrAla: 4.021 ± 0.107	0.352ThrCys: 0.352 ± 0.025	3.183ThrAsp: 3.183 ± 0.105	3.102ThrGlu: 3.102 ± 0.064	3.045ThrPhe: 3.045 ± 0.057	3.621ThrGly: 3.621 ± 0.1	0.933ThrHis: 0.933 ± 0.031	5.225ThrIle: 5.225 ± 0.099	3.383ThrLys: 3.383 ± 0.056	5.2ThrLeu: 5.2 ± 0.085	0.934ThrMet: 0.934 ± 0.029	3.463ThrAsn: 3.463 ± 0.086	2.502ThrPro: 2.502 ± 0.066	1.723ThrGln: 1.723 ± 0.04	1.477ThrArg: 1.477 ± 0.038	4.166ThrSer: 4.166 ± 0.107	3.791ThrThr: 3.791 ± 0.11	3.887ThrVal: 3.887 ± 0.129	0.55ThrTrp: 0.55 ± 0.028	2.435ThrTyr: 2.435 ± 0.072	0.0ThrXaa: 0.0 ± 0.0
Val	4.198ValAla: 4.198 ± 0.065	0.51ValCys: 0.51 ± 0.024	3.651ValAsp: 3.651 ± 0.069	3.973ValGlu: 3.973 ± 0.068	3.242ValPhe: 3.242 ± 0.061	4.176ValGly: 4.176 ± 0.068	0.964ValHis: 0.964 ± 0.033	4.878ValIle: 4.878 ± 0.08	4.387ValLys: 4.387 ± 0.073	5.568ValLeu: 5.568 ± 0.076	1.317ValMet: 1.317 ± 0.035	3.928ValAsn: 3.928 ± 0.075	2.04ValPro: 2.04 ± 0.046	1.85ValGln: 1.85 ± 0.043	2.021ValArg: 2.021 ± 0.05	4.54ValSer: 4.54 ± 0.086	3.491ValThr: 3.491 ± 0.119	4.257ValVal: 4.257 ± 0.075	0.626ValTrp: 0.626 ± 0.024	2.429ValTyr: 2.429 ± 0.048	0.001ValXaa: 0.001 ± 0.001
Trp	0.586TrpAla: 0.586 ± 0.025	0.092TrpCys: 0.092 ± 0.009	0.621TrpAsp: 0.621 ± 0.026	0.644TrpGlu: 0.644 ± 0.027	0.492TrpPhe: 0.492 ± 0.022	0.69TrpGly: 0.69 ± 0.025	0.214TrpHis: 0.214 ± 0.013	0.79TrpIle: 0.79 ± 0.026	0.829TrpLys: 0.829 ± 0.024	0.911TrpLeu: 0.911 ± 0.032	0.302TrpMet: 0.302 ± 0.017	0.694TrpAsn: 0.694 ± 0.027	0.245TrpPro: 0.245 ± 0.016	0.367TrpGln: 0.367 ± 0.02	0.421TrpArg: 0.421 ± 0.021	0.79TrpSer: 0.79 ± 0.04	0.603TrpThr: 0.603 ± 0.029	0.644TrpVal: 0.644 ± 0.025	0.146TrpTrp: 0.146 ± 0.012	0.431TrpTyr: 0.431 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.414TyrAla: 2.414 ± 0.048	0.38TyrCys: 0.38 ± 0.019	2.329TyrAsp: 2.329 ± 0.057	2.351TyrGlu: 2.351 ± 0.053	2.626TyrPhe: 2.626 ± 0.051	2.617TyrGly: 2.617 ± 0.059	0.842TyrHis: 0.842 ± 0.032	2.87TyrIle: 2.87 ± 0.054	2.645TyrLys: 2.645 ± 0.051	4.125TyrLeu: 4.125 ± 0.077	0.723TyrMet: 0.723 ± 0.028	2.552TyrAsn: 2.552 ± 0.068	1.55TyrPro: 1.55 ± 0.043	1.719TyrGln: 1.719 ± 0.044	1.737TyrArg: 1.737 ± 0.041	3.298TyrSer: 3.298 ± 0.066	2.429TyrThr: 2.429 ± 0.075	2.073TyrVal: 2.073 ± 0.045	0.559TyrTrp: 0.559 ± 0.022	2.119TyrTyr: 2.119 ± 0.062	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 3010 proteins (1071256 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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