Amino acid dipepetide frequency for Infectious salmon anemia virus (isolate Atlantic salmon/Norway/810/9/99) (ISAV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.972AlaAla: 3.972 ± 0.823
1.168AlaCys: 1.168 ± 0.526
3.505AlaAsp: 3.505 ± 1.054
2.804AlaGlu: 2.804 ± 1.105
3.271AlaPhe: 3.271 ± 0.846
3.505AlaGly: 3.505 ± 0.865
0.0AlaHis: 0.0 ± 0.0
3.271AlaIle: 3.271 ± 1.081
3.271AlaLys: 3.271 ± 1.384
6.075AlaLeu: 6.075 ± 1.1
3.037AlaMet: 3.037 ± 0.799
3.037AlaAsn: 3.037 ± 0.691
2.103AlaPro: 2.103 ± 0.703
1.168AlaGln: 1.168 ± 0.547
2.804AlaArg: 2.804 ± 0.611
5.14AlaSer: 5.14 ± 0.773
3.505AlaThr: 3.505 ± 0.898
3.972AlaVal: 3.972 ± 0.875
0.467AlaTrp: 0.467 ± 0.318
0.935AlaTyr: 0.935 ± 0.537
0.0AlaXaa: 0.0 ± 0.0
Cys
0.467CysAla: 0.467 ± 0.318
0.935CysCys: 0.935 ± 0.448
0.935CysAsp: 0.935 ± 0.502
1.636CysGlu: 1.636 ± 0.739
0.935CysPhe: 0.935 ± 0.459
1.869CysGly: 1.869 ± 0.943
0.467CysHis: 0.467 ± 0.386
1.168CysIle: 1.168 ± 0.469
1.869CysLys: 1.869 ± 0.616
2.103CysLeu: 2.103 ± 0.638
0.701CysMet: 0.701 ± 0.291
0.467CysAsn: 0.467 ± 0.325
2.103CysPro: 2.103 ± 0.663
0.701CysGln: 0.701 ± 0.551
1.636CysArg: 1.636 ± 0.682
1.402CysSer: 1.402 ± 0.951
2.103CysThr: 2.103 ± 0.688
2.103CysVal: 2.103 ± 0.805
0.467CysTrp: 0.467 ± 0.318
0.234CysTyr: 0.234 ± 0.263
0.234CysXaa: 0.234 ± 0.234
Asp
2.57AspAla: 2.57 ± 0.867
0.701AspCys: 0.701 ± 0.298
3.505AspAsp: 3.505 ± 1.426
6.075AspGlu: 6.075 ± 1.093
2.57AspPhe: 2.57 ± 0.749
4.206AspGly: 4.206 ± 0.852
0.701AspHis: 0.701 ± 0.523
2.804AspIle: 2.804 ± 0.777
3.738AspLys: 3.738 ± 1.077
3.037AspLeu: 3.037 ± 0.938
1.636AspMet: 1.636 ± 0.642
2.103AspAsn: 2.103 ± 0.565
2.103AspPro: 2.103 ± 0.503
2.804AspGln: 2.804 ± 0.597
3.738AspArg: 3.738 ± 0.625
3.972AspSer: 3.972 ± 0.755
3.037AspThr: 3.037 ± 0.632
3.271AspVal: 3.271 ± 0.572
1.168AspTrp: 1.168 ± 0.565
0.935AspTyr: 0.935 ± 0.45
0.0AspXaa: 0.0 ± 0.0
Glu
5.14GluAla: 5.14 ± 0.447
1.636GluCys: 1.636 ± 0.46
3.972GluAsp: 3.972 ± 1.15
7.009GluGlu: 7.009 ± 1.211
3.271GluPhe: 3.271 ± 0.763
5.841GluGly: 5.841 ± 1.165
0.467GluHis: 0.467 ± 0.263
2.804GluIle: 2.804 ± 0.488
6.075GluLys: 6.075 ± 1.437
6.776GluLeu: 6.776 ± 1.518
2.103GluMet: 2.103 ± 0.575
3.271GluAsn: 3.271 ± 0.46
1.869GluPro: 1.869 ± 0.567
2.336GluGln: 2.336 ± 0.859
4.673GluArg: 4.673 ± 1.537
3.037GluSer: 3.037 ± 0.878
5.374GluThr: 5.374 ± 0.79
5.841GluVal: 5.841 ± 0.75
0.701GluTrp: 0.701 ± 0.278
2.336GluTyr: 2.336 ± 0.744
0.0GluXaa: 0.0 ± 0.0
Phe
0.935PheAla: 0.935 ± 0.467
1.402PheCys: 1.402 ± 0.716
2.336PheAsp: 2.336 ± 0.811
2.57PheGlu: 2.57 ± 0.45
0.701PhePhe: 0.701 ± 0.283
1.636PheGly: 1.636 ± 0.562
0.467PheHis: 0.467 ± 0.318
3.271PheIle: 3.271 ± 0.801
1.168PheLys: 1.168 ± 0.481
3.738PheLeu: 3.738 ± 0.732
0.935PheMet: 0.935 ± 0.406
1.869PheAsn: 1.869 ± 0.599
1.869PhePro: 1.869 ± 0.617
0.935PheGln: 0.935 ± 0.469
2.103PheArg: 2.103 ± 0.429
4.206PheSer: 4.206 ± 0.822
3.505PheThr: 3.505 ± 0.824
3.271PheVal: 3.271 ± 1.129
0.467PheTrp: 0.467 ± 0.28
1.168PheTyr: 1.168 ± 0.511
0.0PheXaa: 0.0 ± 0.0
Gly
4.673GlyAla: 4.673 ± 1.148
1.869GlyCys: 1.869 ± 0.89
4.673GlyAsp: 4.673 ± 0.957
6.075GlyGlu: 6.075 ± 1.001
3.037GlyPhe: 3.037 ± 1.086
6.776GlyGly: 6.776 ± 1.289
0.701GlyHis: 0.701 ± 0.35
4.206GlyIle: 4.206 ± 0.85
6.075GlyLys: 6.075 ± 0.735
7.71GlyLeu: 7.71 ± 0.992
3.972GlyMet: 3.972 ± 1.024
3.972GlyAsn: 3.972 ± 0.935
2.336GlyPro: 2.336 ± 0.78
2.336GlyGln: 2.336 ± 0.674
4.907GlyArg: 4.907 ± 1.348
5.14GlySer: 5.14 ± 1.773
3.505GlyThr: 3.505 ± 0.866
7.944GlyVal: 7.944 ± 1.003
1.402GlyTrp: 1.402 ± 0.571
2.103GlyTyr: 2.103 ± 0.461
0.0GlyXaa: 0.0 ± 0.0
His
0.935HisAla: 0.935 ± 0.526
0.467HisCys: 0.467 ± 0.353
0.234HisAsp: 0.234 ± 0.234
0.467HisGlu: 0.467 ± 0.33
0.467HisPhe: 0.467 ± 0.31
1.636HisGly: 1.636 ± 0.767
0.701HisHis: 0.701 ± 0.383
0.467HisIle: 0.467 ± 0.374
0.701HisLys: 0.701 ± 0.383
0.701HisLeu: 0.701 ± 0.703
0.234HisMet: 0.234 ± 0.192
0.234HisAsn: 0.234 ± 0.269
0.234HisPro: 0.234 ± 0.187
0.234HisGln: 0.234 ± 0.289
0.701HisArg: 0.701 ± 0.49
1.168HisSer: 1.168 ± 0.464
0.467HisThr: 0.467 ± 0.27
0.467HisVal: 0.467 ± 0.263
0.701HisTrp: 0.701 ± 0.27
0.234HisTyr: 0.234 ± 0.237
0.0HisXaa: 0.0 ± 0.0
Ile
3.271IleAla: 3.271 ± 0.845
1.168IleCys: 1.168 ± 0.523
2.57IleAsp: 2.57 ± 0.425
2.57IleGlu: 2.57 ± 0.677
1.636IlePhe: 1.636 ± 0.555
4.673IleGly: 4.673 ± 0.928
0.234IleHis: 0.234 ± 0.237
3.037IleIle: 3.037 ± 0.79
3.738IleLys: 3.738 ± 1.021
2.804IleLeu: 2.804 ± 0.714
1.168IleMet: 1.168 ± 0.717
2.336IleAsn: 2.336 ± 0.73
1.636IlePro: 1.636 ± 0.447
2.103IleGln: 2.103 ± 0.623
2.57IleArg: 2.57 ± 0.607
5.14IleSer: 5.14 ± 1.252
2.804IleThr: 2.804 ± 0.671
4.206IleVal: 4.206 ± 0.996
1.402IleTrp: 1.402 ± 0.339
0.935IleTyr: 0.935 ± 0.554
0.0IleXaa: 0.0 ± 0.0
Lys
4.907LysAla: 4.907 ± 0.808
1.869LysCys: 1.869 ± 0.615
2.103LysAsp: 2.103 ± 0.413
5.14LysGlu: 5.14 ± 1.003
1.869LysPhe: 1.869 ± 0.561
7.009LysGly: 7.009 ± 1.152
0.935LysHis: 0.935 ± 0.415
3.972LysIle: 3.972 ± 0.926
5.14LysLys: 5.14 ± 1.124
4.439LysLeu: 4.439 ± 1.234
3.972LysMet: 3.972 ± 1.338
3.972LysAsn: 3.972 ± 0.972
2.103LysPro: 2.103 ± 0.607
2.103LysGln: 2.103 ± 0.748
4.673LysArg: 4.673 ± 1.006
4.907LysSer: 4.907 ± 1.19
5.841LysThr: 5.841 ± 1.347
4.439LysVal: 4.439 ± 0.58
0.935LysTrp: 0.935 ± 0.425
3.037LysTyr: 3.037 ± 1.053
0.467LysXaa: 0.467 ± 0.469
Leu
3.972LeuAla: 3.972 ± 1.177
2.103LeuCys: 2.103 ± 0.58
5.607LeuAsp: 5.607 ± 0.902
6.776LeuGlu: 6.776 ± 1.11
2.57LeuPhe: 2.57 ± 0.802
4.907LeuGly: 4.907 ± 1.303
1.168LeuHis: 1.168 ± 0.482
3.738LeuIle: 3.738 ± 0.815
7.71LeuLys: 7.71 ± 1.51
6.308LeuLeu: 6.308 ± 1.235
3.037LeuMet: 3.037 ± 0.818
3.037LeuAsn: 3.037 ± 0.596
1.168LeuPro: 1.168 ± 0.47
2.57LeuGln: 2.57 ± 0.482
5.14LeuArg: 5.14 ± 0.675
4.673LeuSer: 4.673 ± 1.594
5.14LeuThr: 5.14 ± 1.222
5.374LeuVal: 5.374 ± 0.864
0.935LeuTrp: 0.935 ± 0.486
1.869LeuTyr: 1.869 ± 0.56
0.0LeuXaa: 0.0 ± 0.0
Met
3.505MetAla: 3.505 ± 0.916
0.935MetCys: 0.935 ± 0.581
2.336MetAsp: 2.336 ± 0.761
3.505MetGlu: 3.505 ± 0.916
0.701MetPhe: 0.701 ± 0.457
4.439MetGly: 4.439 ± 1.197
0.234MetHis: 0.234 ± 0.289
1.869MetIle: 1.869 ± 0.684
2.804MetLys: 2.804 ± 0.624
2.336MetLeu: 2.336 ± 0.898
2.103MetMet: 2.103 ± 0.463
0.935MetAsn: 0.935 ± 0.481
0.467MetPro: 0.467 ± 0.328
1.168MetGln: 1.168 ± 0.447
3.505MetArg: 3.505 ± 0.81
2.804MetSer: 2.804 ± 0.745
2.336MetThr: 2.336 ± 0.649
3.037MetVal: 3.037 ± 0.987
0.234MetTrp: 0.234 ± 0.2
0.935MetTyr: 0.935 ± 0.398
0.0MetXaa: 0.0 ± 0.0
Asn
2.57AsnAla: 2.57 ± 0.617
0.701AsnCys: 0.701 ± 0.396
2.103AsnAsp: 2.103 ± 0.69
1.869AsnGlu: 1.869 ± 1.227
2.804AsnPhe: 2.804 ± 0.578
4.907AsnGly: 4.907 ± 1.048
0.234AsnHis: 0.234 ± 0.187
2.103AsnIle: 2.103 ± 0.638
3.738AsnLys: 3.738 ± 0.783
3.972AsnLeu: 3.972 ± 0.268
1.402AsnMet: 1.402 ± 0.582
1.402AsnAsn: 1.402 ± 0.654
1.636AsnPro: 1.636 ± 0.552
2.57AsnGln: 2.57 ± 0.513
1.402AsnArg: 1.402 ± 0.393
2.336AsnSer: 2.336 ± 1.125
3.271AsnThr: 3.271 ± 1.239
2.103AsnVal: 2.103 ± 0.763
0.701AsnTrp: 0.701 ± 0.351
0.0AsnTyr: 0.0 ± 0.0
0.234AsnXaa: 0.234 ± 0.234
Pro
1.168ProAla: 1.168 ± 0.532
0.701ProCys: 0.701 ± 0.43
1.869ProAsp: 1.869 ± 0.569
3.505ProGlu: 3.505 ± 0.748
0.701ProPhe: 0.701 ± 0.311
2.804ProGly: 2.804 ± 0.701
0.234ProHis: 0.234 ± 0.289
0.935ProIle: 0.935 ± 0.304
2.804ProLys: 2.804 ± 0.473
1.869ProLeu: 1.869 ± 0.672
0.935ProMet: 0.935 ± 0.527
0.701ProAsn: 0.701 ± 0.439
1.636ProPro: 1.636 ± 0.664
1.168ProGln: 1.168 ± 0.502
1.402ProArg: 1.402 ± 0.508
2.57ProSer: 2.57 ± 0.596
3.037ProThr: 3.037 ± 1.037
1.869ProVal: 1.869 ± 0.573
0.701ProTrp: 0.701 ± 0.482
0.467ProTyr: 0.467 ± 0.469
0.0ProXaa: 0.0 ± 0.0
Gln
1.869GlnAla: 1.869 ± 0.701
0.234GlnCys: 0.234 ± 0.192
1.402GlnAsp: 1.402 ± 0.457
2.103GlnGlu: 2.103 ± 0.39
0.701GlnPhe: 0.701 ± 0.405
3.505GlnGly: 3.505 ± 0.643
0.935GlnHis: 0.935 ± 0.476
1.636GlnIle: 1.636 ± 0.563
2.804GlnLys: 2.804 ± 0.841
2.336GlnLeu: 2.336 ± 0.44
0.935GlnMet: 0.935 ± 0.522
1.636GlnAsn: 1.636 ± 0.527
0.701GlnPro: 0.701 ± 0.434
1.168GlnGln: 1.168 ± 0.397
2.336GlnArg: 2.336 ± 0.702
3.505GlnSer: 3.505 ± 0.771
1.636GlnThr: 1.636 ± 0.389
2.103GlnVal: 2.103 ± 0.774
0.0GlnTrp: 0.0 ± 0.0
0.234GlnTyr: 0.234 ± 0.213
0.0GlnXaa: 0.0 ± 0.0
Arg
3.738ArgAla: 3.738 ± 0.941
1.168ArgCys: 1.168 ± 0.482
3.271ArgAsp: 3.271 ± 0.544
5.374ArgGlu: 5.374 ± 1.415
2.103ArgPhe: 2.103 ± 1.144
4.907ArgGly: 4.907 ± 1.331
1.168ArgHis: 1.168 ± 0.689
3.505ArgIle: 3.505 ± 0.914
4.206ArgLys: 4.206 ± 1.387
3.972ArgLeu: 3.972 ± 0.693
2.57ArgMet: 2.57 ± 0.782
2.57ArgAsn: 2.57 ± 1.011
2.103ArgPro: 2.103 ± 0.641
0.935ArgGln: 0.935 ± 0.378
3.271ArgArg: 3.271 ± 1.067
4.206ArgSer: 4.206 ± 1.264
4.439ArgThr: 4.439 ± 0.86
3.972ArgVal: 3.972 ± 0.753
0.467ArgTrp: 0.467 ± 0.386
1.168ArgTyr: 1.168 ± 0.423
0.0ArgXaa: 0.0 ± 0.0
Ser
5.14SerAla: 5.14 ± 1.537
2.804SerCys: 2.804 ± 1.027
5.374SerAsp: 5.374 ± 0.832
3.972SerGlu: 3.972 ± 1.2
4.439SerPhe: 4.439 ± 1.113
6.308SerGly: 6.308 ± 1.627
0.467SerHis: 0.467 ± 0.386
2.57SerIle: 2.57 ± 0.671
5.841SerLys: 5.841 ± 0.718
5.14SerLeu: 5.14 ± 1.219
3.505SerMet: 3.505 ± 1.225
2.103SerAsn: 2.103 ± 0.908
1.402SerPro: 1.402 ± 0.457
2.57SerGln: 2.57 ± 0.854
3.972SerArg: 3.972 ± 0.85
5.607SerSer: 5.607 ± 1.517
5.14SerThr: 5.14 ± 1.261
5.14SerVal: 5.14 ± 0.71
1.168SerTrp: 1.168 ± 0.505
1.168SerTyr: 1.168 ± 0.504
0.0SerXaa: 0.0 ± 0.0
Thr
2.57ThrAla: 2.57 ± 0.716
1.869ThrCys: 1.869 ± 0.594
3.505ThrAsp: 3.505 ± 0.662
4.907ThrGlu: 4.907 ± 1.014
3.505ThrPhe: 3.505 ± 0.773
6.075ThrGly: 6.075 ± 1.224
0.701ThrHis: 0.701 ± 0.298
3.972ThrIle: 3.972 ± 1.029
3.738ThrLys: 3.738 ± 0.873
6.075ThrLeu: 6.075 ± 1.457
2.57ThrMet: 2.57 ± 1.045
2.336ThrAsn: 2.336 ± 0.716
2.103ThrPro: 2.103 ± 0.682
2.103ThrGln: 2.103 ± 1.177
3.505ThrArg: 3.505 ± 0.821
5.607ThrSer: 5.607 ± 1.215
6.075ThrThr: 6.075 ± 1.158
4.439ThrVal: 4.439 ± 1.111
0.467ThrTrp: 0.467 ± 0.258
0.467ThrTyr: 0.467 ± 0.384
0.0ThrXaa: 0.0 ± 0.0
Val
4.206ValAla: 4.206 ± 1.038
1.402ValCys: 1.402 ± 0.56
3.271ValAsp: 3.271 ± 0.82
6.075ValGlu: 6.075 ± 0.833
2.57ValPhe: 2.57 ± 0.599
5.607ValGly: 5.607 ± 1.019
0.935ValHis: 0.935 ± 0.668
2.103ValIle: 2.103 ± 0.546
6.075ValLys: 6.075 ± 1.519
5.14ValLeu: 5.14 ± 1.151
2.804ValMet: 2.804 ± 0.767
4.439ValAsn: 4.439 ± 0.855
2.804ValPro: 2.804 ± 0.97
1.402ValGln: 1.402 ± 0.509
4.439ValArg: 4.439 ± 0.761
6.542ValSer: 6.542 ± 1.458
3.505ValThr: 3.505 ± 0.603
6.308ValVal: 6.308 ± 0.923
0.467ValTrp: 0.467 ± 0.324
2.57ValTyr: 2.57 ± 0.785
0.0ValXaa: 0.0 ± 0.0
Trp
0.467TrpAla: 0.467 ± 0.342
0.467TrpCys: 0.467 ± 0.474
0.701TrpAsp: 0.701 ± 0.455
0.234TrpGlu: 0.234 ± 0.2
0.234TrpPhe: 0.234 ± 0.237
1.168TrpGly: 1.168 ± 0.543
0.467TrpHis: 0.467 ± 0.469
0.701TrpIle: 0.701 ± 0.439
0.935TrpLys: 0.935 ± 0.508
1.636TrpLeu: 1.636 ± 0.715
1.402TrpMet: 1.402 ± 0.7
0.234TrpAsn: 0.234 ± 0.213
0.0TrpPro: 0.0 ± 0.0
1.168TrpGln: 1.168 ± 0.385
0.935TrpArg: 0.935 ± 0.315
0.935TrpSer: 0.935 ± 0.517
0.467TrpThr: 0.467 ± 0.324
0.234TrpVal: 0.234 ± 0.192
0.467TrpTrp: 0.467 ± 0.372
0.701TrpTyr: 0.701 ± 0.451
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.935TyrAla: 0.935 ± 0.746
0.467TyrCys: 0.467 ± 0.388
1.402TyrAsp: 1.402 ± 0.499
1.869TyrGlu: 1.869 ± 0.74
0.467TyrPhe: 0.467 ± 0.258
1.636TyrGly: 1.636 ± 0.729
0.234TyrHis: 0.234 ± 0.269
1.636TyrIle: 1.636 ± 0.321
1.402TyrLys: 1.402 ± 0.704
1.636TyrLeu: 1.636 ± 0.593
0.935TyrMet: 0.935 ± 0.428
1.402TyrAsn: 1.402 ± 0.329
0.701TyrPro: 0.701 ± 0.363
0.467TyrGln: 0.467 ± 0.285
1.402TyrArg: 1.402 ± 0.59
0.935TyrSer: 0.935 ± 0.455
1.168TyrThr: 1.168 ± 0.488
2.57TyrVal: 2.57 ± 0.566
0.234TyrTrp: 0.234 ± 0.213
0.701TyrTyr: 0.701 ± 0.279
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.467XaaCys: 0.467 ± 0.469
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.234XaaIle: 0.234 ± 0.234
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.234XaaThr: 0.234 ± 0.234
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.234XaaXaa: 0.234 ± 0.234
Statistics based on 10 proteins (4281 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski