Amino acid dipepetide frequency for Faeces associated gemycircularvirus 16

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.273AlaAla: 2.273 ± 1.709
1.136AlaCys: 1.136 ± 0.845
4.545AlaAsp: 4.545 ± 2.187
2.273AlaGlu: 2.273 ± 1.208
1.136AlaPhe: 1.136 ± 0.845
5.682AlaGly: 5.682 ± 1.656
2.273AlaHis: 2.273 ± 1.208
5.682AlaIle: 5.682 ± 1.656
5.682AlaLys: 5.682 ± 1.512
2.273AlaLeu: 2.273 ± 1.689
1.136AlaMet: 1.136 ± 0.854
5.682AlaAsn: 5.682 ± 1.549
3.409AlaPro: 3.409 ± 2.563
7.955AlaGln: 7.955 ± 1.042
6.818AlaArg: 6.818 ± 0.984
6.818AlaSer: 6.818 ± 3.847
2.273AlaThr: 2.273 ± 1.709
3.409AlaVal: 3.409 ± 1.625
0.0AlaTrp: 0.0 ± 0.0
1.136AlaTyr: 1.136 ± 0.854
0.0AlaXaa: 0.0 ± 0.0
Cys
2.273CysAla: 2.273 ± 1.689
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
2.273CysGlu: 2.273 ± 1.208
2.273CysPhe: 2.273 ± 1.164
2.273CysGly: 2.273 ± 1.208
1.136CysHis: 1.136 ± 0.854
4.545CysIle: 4.545 ± 0.79
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
2.273CysAsn: 2.273 ± 1.208
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.136CysArg: 1.136 ± 0.845
1.136CysSer: 1.136 ± 0.854
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.273AspAla: 2.273 ± 0.781
0.0AspCys: 0.0 ± 0.0
4.545AspAsp: 4.545 ± 1.562
4.545AspGlu: 4.545 ± 2.417
4.545AspPhe: 4.545 ± 0.742
5.682AspGly: 5.682 ± 1.656
2.273AspHis: 2.273 ± 1.208
5.682AspIle: 5.682 ± 2.737
1.136AspLys: 1.136 ± 0.854
6.818AspLeu: 6.818 ± 1.05
1.136AspMet: 1.136 ± 0.845
1.136AspAsn: 1.136 ± 0.854
6.818AspPro: 6.818 ± 2.805
2.273AspGln: 2.273 ± 1.208
0.0AspArg: 0.0 ± 0.0
3.409AspSer: 3.409 ± 2.563
2.273AspThr: 2.273 ± 1.208
3.409AspVal: 3.409 ± 1.625
2.273AspTrp: 2.273 ± 1.689
4.545AspTyr: 4.545 ± 0.742
0.0AspXaa: 0.0 ± 0.0
Glu
4.545GluAla: 4.545 ± 0.742
2.273GluCys: 2.273 ± 1.208
0.0GluAsp: 0.0 ± 0.0
1.136GluGlu: 1.136 ± 0.845
5.682GluPhe: 5.682 ± 2.737
2.273GluGly: 2.273 ± 1.208
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
3.409GluLys: 3.409 ± 0.525
2.273GluLeu: 2.273 ± 1.208
2.273GluMet: 2.273 ± 1.461
2.273GluAsn: 2.273 ± 0.781
0.0GluPro: 0.0 ± 0.0
2.273GluGln: 2.273 ± 1.709
3.409GluArg: 3.409 ± 0.525
2.273GluSer: 2.273 ± 1.208
2.273GluThr: 2.273 ± 1.208
7.955GluVal: 7.955 ± 1.042
2.273GluTrp: 2.273 ± 1.208
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.409PheAla: 3.409 ± 0.525
3.409PheCys: 3.409 ± 1.625
4.545PheAsp: 4.545 ± 0.79
0.0PheGlu: 0.0 ± 0.0
3.409PhePhe: 3.409 ± 1.403
3.409PheGly: 3.409 ± 1.625
1.136PheHis: 1.136 ± 0.845
0.0PheIle: 0.0 ± 0.0
5.682PheLys: 5.682 ± 2.104
2.273PheLeu: 2.273 ± 1.208
1.136PheMet: 1.136 ± 0.845
1.136PheAsn: 1.136 ± 0.854
0.0PhePro: 0.0 ± 0.0
2.273PheGln: 2.273 ± 1.164
7.955PheArg: 7.955 ± 1.042
3.409PheSer: 3.409 ± 1.403
2.273PheThr: 2.273 ± 1.709
3.409PheVal: 3.409 ± 1.625
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.818GlyAla: 6.818 ± 1.004
1.136GlyCys: 1.136 ± 0.854
9.091GlyAsp: 9.091 ± 1.58
6.818GlyGlu: 6.818 ± 3.625
1.136GlyPhe: 1.136 ± 0.854
10.227GlyGly: 10.227 ± 4.876
0.0GlyHis: 0.0 ± 0.0
3.409GlyIle: 3.409 ± 1.625
2.273GlyLys: 2.273 ± 0.781
7.955GlyLeu: 7.955 ± 2.851
1.136GlyMet: 1.136 ± 0.854
3.409GlyAsn: 3.409 ± 2.563
1.136GlyPro: 1.136 ± 0.845
1.136GlyGln: 1.136 ± 0.854
11.364GlyArg: 11.364 ± 4.265
4.545GlySer: 4.545 ± 0.742
11.364GlyThr: 11.364 ± 2.628
4.545GlyVal: 4.545 ± 0.742
1.136GlyTrp: 1.136 ± 0.845
3.409GlyTyr: 3.409 ± 0.525
0.0GlyXaa: 0.0 ± 0.0
His
1.136HisAla: 1.136 ± 0.854
0.0HisCys: 0.0 ± 0.0
2.273HisAsp: 2.273 ± 0.781
1.136HisGlu: 1.136 ± 0.854
0.0HisPhe: 0.0 ± 0.0
1.136HisGly: 1.136 ± 0.845
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
6.818HisLeu: 6.818 ± 3.625
1.136HisMet: 1.136 ± 0.845
1.136HisAsn: 1.136 ± 0.854
5.682HisPro: 5.682 ± 1.656
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
1.136HisThr: 1.136 ± 0.854
3.409HisVal: 3.409 ± 1.625
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.682IleAla: 5.682 ± 1.512
0.0IleCys: 0.0 ± 0.0
2.273IleAsp: 2.273 ± 0.781
2.273IleGlu: 2.273 ± 0.781
5.682IlePhe: 5.682 ± 1.549
2.273IleGly: 2.273 ± 1.208
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
5.682IleLys: 5.682 ± 1.656
1.136IleLeu: 1.136 ± 0.854
0.0IleMet: 0.0 ± 0.0
1.136IleAsn: 1.136 ± 0.854
2.273IlePro: 2.273 ± 0.781
0.0IleGln: 0.0 ± 0.0
2.273IleArg: 2.273 ± 1.208
2.273IleSer: 2.273 ± 1.709
1.136IleThr: 1.136 ± 0.854
2.273IleVal: 2.273 ± 1.208
1.136IleTrp: 1.136 ± 0.845
2.273IleTyr: 2.273 ± 1.208
0.0IleXaa: 0.0 ± 0.0
Lys
2.273LysAla: 2.273 ± 0.781
1.136LysCys: 1.136 ± 1.306
3.409LysAsp: 3.409 ± 1.625
2.273LysGlu: 2.273 ± 1.709
3.409LysPhe: 3.409 ± 0.525
7.955LysGly: 7.955 ± 1.042
1.136LysHis: 1.136 ± 0.854
0.0LysIle: 0.0 ± 0.0
1.136LysLys: 1.136 ± 0.854
2.273LysLeu: 2.273 ± 0.781
0.0LysMet: 0.0 ± 0.0
3.409LysAsn: 3.409 ± 0.525
2.273LysPro: 2.273 ± 1.709
0.0LysGln: 0.0 ± 0.0
1.136LysArg: 1.136 ± 0.854
2.273LysSer: 2.273 ± 0.781
4.545LysThr: 4.545 ± 2.187
1.136LysVal: 1.136 ± 0.854
3.409LysTrp: 3.409 ± 1.625
7.955LysTyr: 7.955 ± 1.042
0.0LysXaa: 0.0 ± 0.0
Leu
5.682LeuAla: 5.682 ± 0.258
3.409LeuCys: 3.409 ± 0.525
5.682LeuAsp: 5.682 ± 1.656
5.682LeuGlu: 5.682 ± 1.656
3.409LeuPhe: 3.409 ± 1.625
7.955LeuGly: 7.955 ± 1.038
4.545LeuHis: 4.545 ± 2.417
6.818LeuIle: 6.818 ± 2.341
1.136LeuLys: 1.136 ± 0.854
2.273LeuLeu: 2.273 ± 1.208
0.0LeuMet: 0.0 ± 0.0
1.136LeuAsn: 1.136 ± 0.845
4.545LeuPro: 4.545 ± 0.742
0.0LeuGln: 0.0 ± 0.0
0.0LeuArg: 0.0 ± 0.0
3.409LeuSer: 3.409 ± 0.525
2.273LeuThr: 2.273 ± 1.208
4.545LeuVal: 4.545 ± 0.79
0.0LeuTrp: 0.0 ± 0.0
3.409LeuTyr: 3.409 ± 1.385
0.0LeuXaa: 0.0 ± 0.0
Met
1.136MetAla: 1.136 ± 0.854
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.136MetGlu: 1.136 ± 0.845
1.136MetPhe: 1.136 ± 0.845
1.136MetGly: 1.136 ± 0.854
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.136MetLys: 1.136 ± 0.854
2.273MetLeu: 2.273 ± 1.208
0.0MetMet: 0.0 ± 0.0
1.136MetAsn: 1.136 ± 0.854
1.136MetPro: 1.136 ± 0.854
0.0MetGln: 0.0 ± 0.0
1.136MetArg: 1.136 ± 0.845
1.136MetSer: 1.136 ± 0.854
4.545MetThr: 4.545 ± 0.742
1.136MetVal: 1.136 ± 0.845
0.0MetTrp: 0.0 ± 0.0
1.136MetTyr: 1.136 ± 0.854
0.0MetXaa: 0.0 ± 0.0
Asn
1.136AsnAla: 1.136 ± 0.845
1.136AsnCys: 1.136 ± 0.845
1.136AsnAsp: 1.136 ± 0.854
1.136AsnGlu: 1.136 ± 0.854
2.273AsnPhe: 2.273 ± 1.208
1.136AsnGly: 1.136 ± 0.854
2.273AsnHis: 2.273 ± 0.781
1.136AsnIle: 1.136 ± 0.854
1.136AsnLys: 1.136 ± 0.854
1.136AsnLeu: 1.136 ± 0.854
0.0AsnMet: 0.0 ± 0.0
1.136AsnAsn: 1.136 ± 0.854
2.273AsnPro: 2.273 ± 1.709
0.0AsnGln: 0.0 ± 0.0
2.273AsnArg: 2.273 ± 0.781
5.682AsnSer: 5.682 ± 0.258
1.136AsnThr: 1.136 ± 0.854
6.818AsnVal: 6.818 ± 1.05
0.0AsnTrp: 0.0 ± 0.0
2.273AsnTyr: 2.273 ± 1.709
0.0AsnXaa: 0.0 ± 0.0
Pro
4.545ProAla: 4.545 ± 3.417
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
2.273ProGlu: 2.273 ± 1.208
2.273ProPhe: 2.273 ± 0.781
4.545ProGly: 4.545 ± 0.742
0.0ProHis: 0.0 ± 0.0
1.136ProIle: 1.136 ± 0.845
4.545ProLys: 4.545 ± 2.291
2.273ProLeu: 2.273 ± 1.709
3.409ProMet: 3.409 ± 2.563
2.273ProAsn: 2.273 ± 1.208
0.0ProPro: 0.0 ± 0.0
3.409ProGln: 3.409 ± 2.563
6.818ProArg: 6.818 ± 0.984
5.682ProSer: 5.682 ± 1.549
4.545ProThr: 4.545 ± 0.742
0.0ProVal: 0.0 ± 0.0
2.273ProTrp: 2.273 ± 1.709
3.409ProTyr: 3.409 ± 0.525
0.0ProXaa: 0.0 ± 0.0
Gln
2.273GlnAla: 2.273 ± 1.709
2.273GlnCys: 2.273 ± 1.208
2.273GlnAsp: 2.273 ± 1.208
1.136GlnGlu: 1.136 ± 0.845
1.136GlnPhe: 1.136 ± 0.854
2.273GlnGly: 2.273 ± 1.709
1.136GlnHis: 1.136 ± 0.854
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
2.273GlnLeu: 2.273 ± 1.709
3.409GlnMet: 3.409 ± 2.095
0.0GlnAsn: 0.0 ± 0.0
2.273GlnPro: 2.273 ± 1.709
2.273GlnGln: 2.273 ± 0.781
2.273GlnArg: 2.273 ± 1.709
2.273GlnSer: 2.273 ± 1.208
0.0GlnThr: 0.0 ± 0.0
0.0GlnVal: 0.0 ± 0.0
3.409GlnTrp: 3.409 ± 0.525
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.409ArgAla: 3.409 ± 1.403
0.0ArgCys: 0.0 ± 0.0
3.409ArgAsp: 3.409 ± 1.625
3.409ArgGlu: 3.409 ± 1.625
2.273ArgPhe: 2.273 ± 1.709
9.091ArgGly: 9.091 ± 4.336
2.273ArgHis: 2.273 ± 1.208
0.0ArgIle: 0.0 ± 0.0
5.682ArgLys: 5.682 ± 1.512
0.0ArgLeu: 0.0 ± 0.0
0.0ArgMet: 0.0 ± 0.74
1.136ArgAsn: 1.136 ± 0.854
10.227ArgPro: 10.227 ± 0.807
0.0ArgGln: 0.0 ± 0.0
14.773ArgArg: 14.773 ± 5.523
11.364ArgSer: 11.364 ± 1.449
3.409ArgThr: 3.409 ± 1.403
4.545ArgVal: 4.545 ± 0.742
0.0ArgTrp: 0.0 ± 0.0
4.545ArgTyr: 4.545 ± 0.742
0.0ArgXaa: 0.0 ± 0.0
Ser
2.273SerAla: 2.273 ± 1.709
0.0SerCys: 0.0 ± 0.0
4.545SerAsp: 4.545 ± 2.417
1.136SerGlu: 1.136 ± 0.854
0.0SerPhe: 0.0 ± 0.0
12.5SerGly: 12.5 ± 0.795
0.0SerHis: 0.0 ± 0.0
4.545SerIle: 4.545 ± 2.291
6.818SerLys: 6.818 ± 2.876
5.682SerLeu: 5.682 ± 1.549
1.136SerMet: 1.136 ± 0.854
3.409SerAsn: 3.409 ± 2.563
5.682SerPro: 5.682 ± 0.258
1.136SerGln: 1.136 ± 0.854
4.545SerArg: 4.545 ± 0.79
4.545SerSer: 4.545 ± 0.742
4.545SerThr: 4.545 ± 3.417
2.273SerVal: 2.273 ± 1.709
1.136SerTrp: 1.136 ± 0.845
3.409SerTyr: 3.409 ± 0.525
0.0SerXaa: 0.0 ± 0.0
Thr
1.136ThrAla: 1.136 ± 0.854
0.0ThrCys: 0.0 ± 0.0
1.136ThrAsp: 1.136 ± 0.854
2.273ThrGlu: 2.273 ± 1.709
2.273ThrPhe: 2.273 ± 0.781
5.682ThrGly: 5.682 ± 0.258
1.136ThrHis: 1.136 ± 0.845
4.545ThrIle: 4.545 ± 3.417
2.273ThrLys: 2.273 ± 1.709
7.955ThrLeu: 7.955 ± 3.184
0.0ThrMet: 0.0 ± 0.0
1.136ThrAsn: 1.136 ± 0.854
3.409ThrPro: 3.409 ± 0.525
5.682ThrGln: 5.682 ± 1.656
5.682ThrArg: 5.682 ± 1.512
1.136ThrSer: 1.136 ± 0.845
3.409ThrThr: 3.409 ± 0.525
3.409ThrVal: 3.409 ± 0.525
0.0ThrTrp: 0.0 ± 0.0
4.545ThrTyr: 4.545 ± 0.742
0.0ThrXaa: 0.0 ± 0.0
Val
5.682ValAla: 5.682 ± 1.656
1.136ValCys: 1.136 ± 0.854
9.091ValAsp: 9.091 ± 2.139
3.409ValGlu: 3.409 ± 1.625
4.545ValPhe: 4.545 ± 0.79
1.136ValGly: 1.136 ± 0.854
2.273ValHis: 2.273 ± 1.208
0.0ValIle: 0.0 ± 0.0
2.273ValLys: 2.273 ± 1.689
3.409ValLeu: 3.409 ± 1.625
1.136ValMet: 1.136 ± 0.854
1.136ValAsn: 1.136 ± 0.845
2.273ValPro: 2.273 ± 1.208
1.136ValGln: 1.136 ± 0.854
3.409ValArg: 3.409 ± 1.625
5.682ValSer: 5.682 ± 3.529
4.545ValThr: 4.545 ± 3.417
9.091ValVal: 9.091 ± 2.139
1.136ValTrp: 1.136 ± 0.854
2.273ValTyr: 2.273 ± 0.781
0.0ValXaa: 0.0 ± 0.0
Trp
3.409TrpAla: 3.409 ± 1.625
1.136TrpCys: 1.136 ± 0.845
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.136TrpPhe: 1.136 ± 0.854
1.136TrpGly: 1.136 ± 0.845
1.136TrpHis: 1.136 ± 0.854
1.136TrpIle: 1.136 ± 0.854
1.136TrpLys: 1.136 ± 0.845
4.545TrpLeu: 4.545 ± 2.291
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.136TrpGln: 1.136 ± 0.854
3.409TrpArg: 3.409 ± 0.525
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
10.227TyrAla: 10.227 ± 5.094
1.136TyrCys: 1.136 ± 0.854
6.818TyrAsp: 6.818 ± 2.341
2.273TyrGlu: 2.273 ± 1.208
1.136TyrPhe: 1.136 ± 0.845
4.545TyrGly: 4.545 ± 0.79
2.273TyrHis: 2.273 ± 0.781
1.136TyrIle: 1.136 ± 0.854
0.0TyrLys: 0.0 ± 0.0
2.273TyrLeu: 2.273 ± 1.709
1.136TyrMet: 1.136 ± 0.854
1.136TyrAsn: 1.136 ± 0.854
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
2.273TyrArg: 2.273 ± 1.709
2.273TyrSer: 2.273 ± 1.208
1.136TyrThr: 1.136 ± 0.854
3.409TyrVal: 3.409 ± 0.525
1.136TyrTrp: 1.136 ± 0.854
2.273TyrTyr: 2.273 ± 1.709
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (881 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski