Amino acid dipepetide frequency for Hubei odonate virus 12

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.375AlaAla: 4.375 ± 0.98
1.875AlaCys: 1.875 ± 1.417
3.75AlaAsp: 3.75 ± 0.262
9.375AlaGlu: 9.375 ± 2.346
1.875AlaPhe: 1.875 ± 0.298
6.875AlaGly: 6.875 ± 0.806
1.25AlaHis: 1.25 ± 0.945
1.25AlaIle: 1.25 ± 0.77
2.5AlaLys: 2.5 ± 0.175
6.25AlaLeu: 6.25 ± 1.294
3.125AlaMet: 3.125 ± 0.21
2.5AlaAsn: 2.5 ± 0.175
3.125AlaPro: 3.125 ± 0.21
1.875AlaGln: 1.875 ± 1.155
8.125AlaArg: 8.125 ± 0.139
6.25AlaSer: 6.25 ± 1.278
1.875AlaThr: 1.875 ± 1.417
3.125AlaVal: 3.125 ± 0.647
0.625AlaTrp: 0.625 ± 0.472
1.875AlaTyr: 1.875 ± 1.155
0.0AlaXaa: 0.0 ± 0.0
Cys
1.25CysAla: 1.25 ± 0.77
0.0CysCys: 0.0 ± 0.0
1.875CysAsp: 1.875 ± 0.56
0.0CysGlu: 0.0 ± 0.0
1.875CysPhe: 1.875 ± 0.56
3.125CysGly: 3.125 ± 0.647
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.625CysLys: 0.625 ± 0.472
1.875CysLeu: 1.875 ± 1.417
0.625CysMet: 0.625 ± 0.472
1.25CysAsn: 1.25 ± 0.77
0.625CysPro: 0.625 ± 0.385
0.625CysGln: 0.625 ± 0.472
1.875CysArg: 1.875 ± 0.56
1.25CysSer: 1.25 ± 0.945
1.25CysThr: 1.25 ± 0.945
0.625CysVal: 0.625 ± 0.385
1.875CysTrp: 1.875 ± 0.56
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.25AspAla: 1.25 ± 0.945
1.875AspCys: 1.875 ± 0.298
5.625AspAsp: 5.625 ± 2.608
2.5AspGlu: 2.5 ± 1.54
1.875AspPhe: 1.875 ± 0.298
5.625AspGly: 5.625 ± 0.822
0.625AspHis: 0.625 ± 0.385
3.125AspIle: 3.125 ± 1.068
2.5AspLys: 2.5 ± 0.683
3.75AspLeu: 3.75 ± 0.595
1.25AspMet: 1.25 ± 0.087
2.5AspAsn: 2.5 ± 0.175
3.125AspPro: 3.125 ± 0.647
1.875AspGln: 1.875 ± 1.417
1.25AspArg: 1.25 ± 0.77
7.5AspSer: 7.5 ± 3.763
0.0AspThr: 0.0 ± 0.0
5.625AspVal: 5.625 ± 0.822
0.0AspTrp: 0.0 ± 0.0
1.25AspTyr: 1.25 ± 0.087
0.0AspXaa: 0.0 ± 0.0
Glu
8.125GluAla: 8.125 ± 1.854
1.25GluCys: 1.25 ± 0.77
1.875GluAsp: 1.875 ± 0.56
5.0GluGlu: 5.0 ± 1.365
1.875GluPhe: 1.875 ± 0.298
6.875GluGly: 6.875 ± 1.663
1.25GluHis: 1.25 ± 0.77
2.5GluIle: 2.5 ± 0.683
1.25GluLys: 1.25 ± 0.945
5.0GluLeu: 5.0 ± 0.349
0.625GluMet: 0.625 ± 0.472
1.875GluAsn: 1.875 ± 0.298
2.5GluPro: 2.5 ± 1.032
1.25GluGln: 1.25 ± 0.087
6.875GluArg: 6.875 ± 2.52
1.875GluSer: 1.875 ± 0.56
2.5GluThr: 2.5 ± 0.175
7.5GluVal: 7.5 ± 0.333
2.5GluTrp: 2.5 ± 1.032
1.25GluTyr: 1.25 ± 0.77
0.0GluXaa: 0.0 ± 0.0
Phe
2.5PheAla: 2.5 ± 0.683
1.25PheCys: 1.25 ± 0.087
2.5PheAsp: 2.5 ± 0.683
1.875PheGlu: 1.875 ± 0.298
0.625PhePhe: 0.625 ± 0.472
1.875PheGly: 1.875 ± 0.56
0.625PheHis: 0.625 ± 0.472
1.875PheIle: 1.875 ± 0.298
1.25PheLys: 1.25 ± 0.77
2.5PheLeu: 2.5 ± 1.032
1.25PheMet: 1.25 ± 0.945
0.0PheAsn: 0.0 ± 0.0
1.875PhePro: 1.875 ± 0.56
1.875PheGln: 1.875 ± 1.417
1.25PheArg: 1.25 ± 0.77
2.5PheSer: 2.5 ± 0.175
2.5PheThr: 2.5 ± 0.175
0.625PheVal: 0.625 ± 0.385
0.0PheTrp: 0.0 ± 0.0
1.875PheTyr: 1.875 ± 1.155
0.0PheXaa: 0.0 ± 0.0
Gly
5.0GlyAla: 5.0 ± 2.223
0.625GlyCys: 0.625 ± 0.472
7.5GlyAsp: 7.5 ± 0.524
1.875GlyGlu: 1.875 ± 1.155
1.25GlyPhe: 1.25 ± 0.77
2.5GlyGly: 2.5 ± 1.54
1.875GlyHis: 1.875 ± 1.417
5.0GlyIle: 5.0 ± 0.349
2.5GlyLys: 2.5 ± 0.175
3.75GlyLeu: 3.75 ± 1.119
1.875GlyMet: 1.875 ± 0.298
0.625GlyAsn: 0.625 ± 0.472
5.0GlyPro: 5.0 ± 1.365
2.5GlyGln: 2.5 ± 1.54
10.625GlyArg: 10.625 ± 3.116
3.75GlySer: 3.75 ± 2.31
5.625GlyThr: 5.625 ± 0.036
5.0GlyVal: 5.0 ± 0.349
0.625GlyTrp: 0.625 ± 0.472
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.25HisAla: 1.25 ± 0.77
0.625HisCys: 0.625 ± 0.385
1.875HisAsp: 1.875 ± 1.155
1.25HisGlu: 1.25 ± 0.945
0.625HisPhe: 0.625 ± 0.472
0.625HisGly: 0.625 ± 0.385
1.25HisHis: 1.25 ± 0.087
1.25HisIle: 1.25 ± 0.945
1.25HisLys: 1.25 ± 0.77
2.5HisLeu: 2.5 ± 0.175
0.625HisMet: 0.625 ± 0.385
0.625HisAsn: 0.625 ± 0.472
3.75HisPro: 3.75 ± 0.262
0.625HisGln: 0.625 ± 0.385
4.375HisArg: 4.375 ± 0.98
2.5HisSer: 2.5 ± 0.175
4.375HisThr: 4.375 ± 0.734
1.25HisVal: 1.25 ± 0.087
0.0HisTrp: 0.0 ± 0.0
0.625HisTyr: 0.625 ± 0.385
0.0HisXaa: 0.0 ± 0.0
Ile
5.0IleAla: 5.0 ± 0.349
0.625IleCys: 0.625 ± 0.472
0.0IleAsp: 0.0 ± 0.0
1.25IleGlu: 1.25 ± 0.087
1.25IlePhe: 1.25 ± 0.77
1.25IleGly: 1.25 ± 0.087
1.25IleHis: 1.25 ± 0.087
0.625IleIle: 0.625 ± 0.472
1.875IleLys: 1.875 ± 1.417
3.75IleLeu: 3.75 ± 0.262
0.0IleMet: 0.0 ± 0.0
0.625IleAsn: 0.625 ± 0.385
2.5IlePro: 2.5 ± 1.032
0.625IleGln: 0.625 ± 0.472
1.875IleArg: 1.875 ± 0.56
3.125IleSer: 3.125 ± 1.504
3.125IleThr: 3.125 ± 1.925
5.0IleVal: 5.0 ± 1.365
0.0IleTrp: 0.0 ± 0.0
2.5IleTyr: 2.5 ± 0.683
0.0IleXaa: 0.0 ± 0.0
Lys
3.125LysAla: 3.125 ± 1.504
0.625LysCys: 0.625 ± 0.472
1.875LysAsp: 1.875 ± 1.155
3.75LysGlu: 3.75 ± 1.119
0.625LysPhe: 0.625 ± 0.472
0.625LysGly: 0.625 ± 0.472
1.875LysHis: 1.875 ± 1.155
1.25LysIle: 1.25 ± 0.945
1.25LysLys: 1.25 ± 0.945
3.75LysLeu: 3.75 ± 1.119
0.0LysMet: 0.0 ± 0.0
1.875LysAsn: 1.875 ± 0.298
0.625LysPro: 0.625 ± 0.472
1.25LysGln: 1.25 ± 0.087
5.0LysArg: 5.0 ± 2.064
0.625LysSer: 0.625 ± 0.472
1.875LysThr: 1.875 ± 0.298
3.125LysVal: 3.125 ± 1.068
0.625LysTrp: 0.625 ± 0.385
1.25LysTyr: 1.25 ± 0.945
0.0LysXaa: 0.0 ± 0.0
Leu
7.5LeuAla: 7.5 ± 0.524
2.5LeuCys: 2.5 ± 0.175
1.25LeuAsp: 1.25 ± 0.087
9.375LeuGlu: 9.375 ± 2.798
1.25LeuPhe: 1.25 ± 0.77
5.0LeuGly: 5.0 ± 1.207
3.75LeuHis: 3.75 ± 0.262
5.0LeuIle: 5.0 ± 0.349
3.125LeuLys: 3.125 ± 0.647
6.25LeuLeu: 6.25 ± 2.151
0.625LeuMet: 0.625 ± 0.472
1.25LeuAsn: 1.25 ± 0.087
5.0LeuPro: 5.0 ± 0.508
3.125LeuGln: 3.125 ± 1.504
10.625LeuArg: 10.625 ± 1.171
3.125LeuSer: 3.125 ± 0.21
5.0LeuThr: 5.0 ± 0.349
3.75LeuVal: 3.75 ± 0.262
0.0LeuTrp: 0.0 ± 0.0
2.5LeuTyr: 2.5 ± 0.175
0.0LeuXaa: 0.0 ± 0.0
Met
1.25MetAla: 1.25 ± 0.77
0.0MetCys: 0.0 ± 0.0
0.625MetAsp: 0.625 ± 0.385
1.875MetGlu: 1.875 ± 0.56
0.0MetPhe: 0.0 ± 0.0
1.25MetGly: 1.25 ± 0.945
0.625MetHis: 0.625 ± 0.472
0.625MetIle: 0.625 ± 0.472
0.0MetLys: 0.0 ± 0.0
1.875MetLeu: 1.875 ± 0.298
1.25MetMet: 1.25 ± 0.945
0.625MetAsn: 0.625 ± 0.472
2.5MetPro: 2.5 ± 0.175
0.625MetGln: 0.625 ± 0.385
2.5MetArg: 2.5 ± 0.683
0.625MetSer: 0.625 ± 0.385
3.125MetThr: 3.125 ± 1.504
1.875MetVal: 1.875 ± 0.56
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.5AsnAla: 2.5 ± 0.683
0.0AsnCys: 0.0 ± 0.0
1.25AsnAsp: 1.25 ± 0.77
1.25AsnGlu: 1.25 ± 0.77
1.25AsnPhe: 1.25 ± 0.945
1.25AsnGly: 1.25 ± 0.087
1.875AsnHis: 1.875 ± 1.155
0.625AsnIle: 0.625 ± 0.472
1.25AsnLys: 1.25 ± 0.087
4.375AsnLeu: 4.375 ± 0.734
0.0AsnMet: 0.0 ± 0.294
0.625AsnAsn: 0.625 ± 0.385
1.25AsnPro: 1.25 ± 0.77
1.875AsnGln: 1.875 ± 0.298
1.25AsnArg: 1.25 ± 0.087
0.625AsnSer: 0.625 ± 0.385
3.75AsnThr: 3.75 ± 1.119
1.25AsnVal: 1.25 ± 0.945
0.625AsnTrp: 0.625 ± 0.385
0.625AsnTyr: 0.625 ± 0.385
0.0AsnXaa: 0.0 ± 0.0
Pro
6.875ProAla: 6.875 ± 0.052
0.0ProCys: 0.0 ± 0.0
1.875ProAsp: 1.875 ± 0.298
2.5ProGlu: 2.5 ± 0.175
4.375ProPhe: 4.375 ± 0.734
3.75ProGly: 3.75 ± 0.595
1.25ProHis: 1.25 ± 0.945
1.875ProIle: 1.875 ± 0.298
1.875ProLys: 1.875 ± 0.56
3.125ProLeu: 3.125 ± 0.647
2.5ProMet: 2.5 ± 1.032
1.25ProAsn: 1.25 ± 0.087
13.75ProPro: 13.75 ± 2.469
1.25ProGln: 1.25 ± 0.77
7.5ProArg: 7.5 ± 1.191
5.0ProSer: 5.0 ± 0.349
5.625ProThr: 5.625 ± 0.036
2.5ProVal: 2.5 ± 0.683
1.25ProTrp: 1.25 ± 0.77
3.125ProTyr: 3.125 ± 0.647
0.0ProXaa: 0.0 ± 0.0
Gln
0.625GlnAla: 0.625 ± 0.385
1.875GlnCys: 1.875 ± 0.56
1.875GlnAsp: 1.875 ± 0.298
0.0GlnGlu: 0.0 ± 0.0
1.875GlnPhe: 1.875 ± 1.417
0.625GlnGly: 0.625 ± 0.385
1.875GlnHis: 1.875 ± 0.298
1.875GlnIle: 1.875 ± 0.298
1.875GlnLys: 1.875 ± 0.56
3.125GlnLeu: 3.125 ± 1.504
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
3.125GlnPro: 3.125 ± 0.647
0.625GlnGln: 0.625 ± 0.472
5.0GlnArg: 5.0 ± 1.365
2.5GlnSer: 2.5 ± 0.175
1.25GlnThr: 1.25 ± 0.087
2.5GlnVal: 2.5 ± 0.175
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
8.125ArgAla: 8.125 ± 1.576
3.125ArgCys: 3.125 ± 2.362
4.375ArgAsp: 4.375 ± 0.98
3.75ArgGlu: 3.75 ± 0.262
2.5ArgPhe: 2.5 ± 0.175
9.375ArgGly: 9.375 ± 3.203
4.375ArgHis: 4.375 ± 0.98
1.25ArgIle: 1.25 ± 0.087
3.75ArgLys: 3.75 ± 1.119
6.25ArgLeu: 6.25 ± 2.993
3.125ArgMet: 3.125 ± 0.21
5.625ArgAsn: 5.625 ± 0.036
6.25ArgPro: 6.25 ± 2.135
5.0ArgGln: 5.0 ± 0.508
10.0ArgArg: 10.0 ± 1.873
7.5ArgSer: 7.5 ± 2.239
5.0ArgThr: 5.0 ± 0.508
7.5ArgVal: 7.5 ± 0.524
5.0ArgTrp: 5.0 ± 1.365
1.875ArgTyr: 1.875 ± 1.417
0.0ArgXaa: 0.0 ± 0.0
Ser
3.75SerAla: 3.75 ± 1.119
2.5SerCys: 2.5 ± 1.032
5.0SerAsp: 5.0 ± 0.508
3.125SerGlu: 3.125 ± 0.21
3.125SerPhe: 3.125 ± 1.068
6.25SerGly: 6.25 ± 2.993
0.625SerHis: 0.625 ± 0.385
1.875SerIle: 1.875 ± 0.298
0.0SerLys: 0.0 ± 0.0
3.125SerLeu: 3.125 ± 0.21
0.0SerMet: 0.0 ± 0.0
1.875SerAsn: 1.875 ± 1.155
6.25SerPro: 6.25 ± 1.294
1.875SerGln: 1.875 ± 0.56
8.75SerArg: 8.75 ± 0.611
8.75SerSer: 8.75 ± 1.469
5.0SerThr: 5.0 ± 0.349
4.375SerVal: 4.375 ± 1.592
1.25SerTrp: 1.25 ± 0.945
2.5SerTyr: 2.5 ± 1.032
0.0SerXaa: 0.0 ± 0.0
Thr
3.75ThrAla: 3.75 ± 0.262
1.25ThrCys: 1.25 ± 0.087
3.125ThrAsp: 3.125 ± 1.504
1.25ThrGlu: 1.25 ± 0.087
1.875ThrPhe: 1.875 ± 0.56
5.0ThrGly: 5.0 ± 1.365
3.125ThrHis: 3.125 ± 1.068
2.5ThrIle: 2.5 ± 1.032
3.125ThrLys: 3.125 ± 1.504
8.75ThrLeu: 8.75 ± 0.246
1.875ThrMet: 1.875 ± 1.204
0.625ThrAsn: 0.625 ± 0.385
4.375ThrPro: 4.375 ± 1.838
0.0ThrGln: 0.0 ± 0.0
5.0ThrArg: 5.0 ± 1.207
4.375ThrSer: 4.375 ± 0.734
5.0ThrThr: 5.0 ± 1.207
4.375ThrVal: 4.375 ± 1.592
2.5ThrTrp: 2.5 ± 0.683
3.125ThrTyr: 3.125 ± 1.068
0.0ThrXaa: 0.0 ± 0.0
Val
3.75ValAla: 3.75 ± 0.262
0.0ValCys: 0.0 ± 0.0
5.0ValAsp: 5.0 ± 1.365
11.25ValGlu: 11.25 ± 0.786
1.875ValPhe: 1.875 ± 1.155
3.75ValGly: 3.75 ± 1.453
1.25ValHis: 1.25 ± 0.945
1.875ValIle: 1.875 ± 0.298
2.5ValLys: 2.5 ± 1.032
6.25ValLeu: 6.25 ± 2.151
1.25ValMet: 1.25 ± 0.77
2.5ValAsn: 2.5 ± 0.683
4.375ValPro: 4.375 ± 1.592
1.875ValGln: 1.875 ± 1.417
6.25ValArg: 6.25 ± 1.278
4.375ValSer: 4.375 ± 2.449
5.0ValThr: 5.0 ± 0.508
8.125ValVal: 8.125 ± 3.29
0.0ValTrp: 0.0 ± 0.0
2.5ValTyr: 2.5 ± 0.683
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.625TrpCys: 0.625 ± 0.385
0.625TrpAsp: 0.625 ± 0.472
0.625TrpGlu: 0.625 ± 0.385
0.0TrpPhe: 0.0 ± 0.0
1.25TrpGly: 1.25 ± 0.087
1.25TrpHis: 1.25 ± 0.77
1.25TrpIle: 1.25 ± 0.087
0.625TrpLys: 0.625 ± 0.472
2.5TrpLeu: 2.5 ± 1.032
0.0TrpMet: 0.0 ± 0.0
0.625TrpAsn: 0.625 ± 0.472
0.0TrpPro: 0.0 ± 0.0
0.625TrpGln: 0.625 ± 0.385
1.875TrpArg: 1.875 ± 0.56
0.625TrpSer: 0.625 ± 0.385
0.0TrpThr: 0.0 ± 0.0
3.75TrpVal: 3.75 ± 0.595
0.0TrpTrp: 0.0 ± 0.0
0.625TrpTyr: 0.625 ± 0.385
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.875TyrAla: 1.875 ± 0.298
0.0TyrCys: 0.0 ± 0.0
1.25TyrAsp: 1.25 ± 0.77
1.875TyrGlu: 1.875 ± 1.155
0.625TyrPhe: 0.625 ± 0.472
0.625TyrGly: 0.625 ± 0.472
1.25TyrHis: 1.25 ± 0.087
0.625TyrIle: 0.625 ± 0.472
1.875TyrLys: 1.875 ± 1.155
1.25TyrLeu: 1.25 ± 0.087
0.625TyrMet: 0.625 ± 0.385
1.25TyrAsn: 1.25 ± 0.087
1.25TyrPro: 1.25 ± 0.087
1.25TyrGln: 1.25 ± 0.087
3.75TyrArg: 3.75 ± 0.595
3.125TyrSer: 3.125 ± 0.647
3.125TyrThr: 3.125 ± 0.21
1.875TyrVal: 1.875 ± 0.298
0.0TyrTrp: 0.0 ± 0.0
2.5TyrTyr: 2.5 ± 1.54
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1601 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski