Measles virus (strain Edmonston-AIK-C vaccine) (MeV) (Subacute sclerose panencephalitis virus)

Taxonomy: Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina; Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae; Morbillivirus; Measles morbillivirus

Average proteome isoelectric point is 7.03

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P35975|L_MEASA RNA-directed RNA polymerase L OS=Measles virus (strain Edmonston-AIK-C vaccine) OX=36408 GN=L PE=3 SV=1
MM1 pKa = 8.15AEE3 pKa = 3.63EE4 pKa = 3.91QARR7 pKa = 11.84HH8 pKa = 4.84VKK10 pKa = 10.61NGLEE14 pKa = 4.48CIRR17 pKa = 11.84ALKK20 pKa = 10.54AEE22 pKa = 5.1PIGSLAIEE30 pKa = 4.18EE31 pKa = 5.21AMAAWSEE38 pKa = 4.06ISDD41 pKa = 3.59NPGQEE46 pKa = 3.43RR47 pKa = 11.84ATCRR51 pKa = 11.84EE52 pKa = 4.01EE53 pKa = 4.01KK54 pKa = 10.5AGSSGLSKK62 pKa = 10.51PCLSAIGSTEE72 pKa = 3.52GGAPRR77 pKa = 11.84IRR79 pKa = 11.84GQGPGEE85 pKa = 4.18SDD87 pKa = 4.51DD88 pKa = 4.25DD89 pKa = 4.84AEE91 pKa = 4.54TLGIPPRR98 pKa = 11.84NLQASSTGLQCYY110 pKa = 8.82YY111 pKa = 10.96VYY113 pKa = 10.8DD114 pKa = 3.84HH115 pKa = 6.99SGEE118 pKa = 4.12AVKK121 pKa = 10.71GIQDD125 pKa = 3.6ADD127 pKa = 3.98SIMVQSGLDD136 pKa = 3.52GDD138 pKa = 4.4STLSGGDD145 pKa = 3.54NEE147 pKa = 5.15SEE149 pKa = 4.21NSDD152 pKa = 3.37VDD154 pKa = 3.07IGEE157 pKa = 4.99PDD159 pKa = 3.41TEE161 pKa = 4.81GYY163 pKa = 10.86AITDD167 pKa = 3.66RR168 pKa = 11.84GSAPISMGFRR178 pKa = 11.84ASDD181 pKa = 3.44VEE183 pKa = 4.22TAEE186 pKa = 4.19GGEE189 pKa = 3.83IHH191 pKa = 6.91EE192 pKa = 4.65LLRR195 pKa = 11.84LQSRR199 pKa = 11.84GNNFPKK205 pKa = 10.39LGKK208 pKa = 7.92TLNVPPPPDD217 pKa = 4.04PGRR220 pKa = 11.84ASTSGTPIKK229 pKa = 10.55KK230 pKa = 8.26GTEE233 pKa = 3.33RR234 pKa = 11.84RR235 pKa = 11.84LASFGTEE242 pKa = 3.4IASLLTGGATQCARR256 pKa = 11.84KK257 pKa = 9.94SPSEE261 pKa = 3.79PSGPGAPAGNVPEE274 pKa = 4.34YY275 pKa = 10.72VSNAALIQEE284 pKa = 4.51WTPEE288 pKa = 4.01SGTTISPRR296 pKa = 11.84SQNNEE301 pKa = 3.77EE302 pKa = 4.15GGDD305 pKa = 3.84YY306 pKa = 11.05YY307 pKa = 11.31DD308 pKa = 5.98DD309 pKa = 4.14EE310 pKa = 5.28LFSDD314 pKa = 3.92VQDD317 pKa = 3.6IKK319 pKa = 10.35TALAKK324 pKa = 10.19IHH326 pKa = 7.01EE327 pKa = 5.15DD328 pKa = 3.2NQKK331 pKa = 10.34IISKK335 pKa = 10.59LEE337 pKa = 3.76SLLLLKK343 pKa = 11.16GEE345 pKa = 4.15VEE347 pKa = 4.55SIKK350 pKa = 10.81KK351 pKa = 9.72QINRR355 pKa = 11.84QNISISTLEE364 pKa = 3.97GHH366 pKa = 7.29LSSIMIAIPGLGKK379 pKa = 10.47DD380 pKa = 4.25PNDD383 pKa = 3.35PTADD387 pKa = 3.52VEE389 pKa = 4.53INPDD393 pKa = 3.86LKK395 pKa = 10.89PIIGRR400 pKa = 11.84DD401 pKa = 3.18SGRR404 pKa = 11.84ALAEE408 pKa = 4.04VLKK411 pKa = 10.88KK412 pKa = 10.12PVASRR417 pKa = 11.84QLQGMTNGRR426 pKa = 11.84TSSRR430 pKa = 11.84GQLLKK435 pKa = 10.61EE436 pKa = 4.11FQPKK440 pKa = 10.08PIGKK444 pKa = 9.62KK445 pKa = 8.47MSSAVGFVPDD455 pKa = 4.19TGPASRR461 pKa = 11.84SVIRR465 pKa = 11.84SIIKK469 pKa = 10.0SSRR472 pKa = 11.84LEE474 pKa = 3.95EE475 pKa = 3.99DD476 pKa = 2.97RR477 pKa = 11.84KK478 pKa = 10.54RR479 pKa = 11.84YY480 pKa = 10.31LMTLLDD486 pKa = 5.15DD487 pKa = 4.11IKK489 pKa = 11.13GANDD493 pKa = 3.38LAKK496 pKa = 10.19FHH498 pKa = 6.04QMLMKK503 pKa = 10.09IIMKK507 pKa = 10.21

Molecular weight: 54.1 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P35977|C_MEASA Protein C OS=Measles virus (strain Edmonston-AIK-C vaccine) OX=36408 GN=P/V/C PE=1 SV=1
MM1 pKa = 7.9SKK3 pKa = 9.54TDD5 pKa = 3.3WNASGLSRR13 pKa = 11.84PSPSAHH19 pKa = 5.35WPSRR23 pKa = 11.84KK24 pKa = 9.12LWQHH28 pKa = 4.13GQKK31 pKa = 10.36YY32 pKa = 7.22QTTQDD37 pKa = 3.24RR38 pKa = 11.84SEE40 pKa = 4.24PPAGKK45 pKa = 9.52RR46 pKa = 11.84RR47 pKa = 11.84QAVRR51 pKa = 11.84VSANHH56 pKa = 7.14ASQQLDD62 pKa = 3.29QLKK65 pKa = 10.12AVHH68 pKa = 6.38LASAVRR74 pKa = 11.84DD75 pKa = 3.66LEE77 pKa = 4.45RR78 pKa = 11.84AMTTLKK84 pKa = 10.51LWEE87 pKa = 4.53SPQEE91 pKa = 4.11ISRR94 pKa = 11.84HH95 pKa = 4.01QALGYY100 pKa = 9.1SVIMFMITAVKK111 pKa = 10.1RR112 pKa = 11.84LRR114 pKa = 11.84EE115 pKa = 4.28SKK117 pKa = 10.12MLTLSWFNQALMVIAPYY134 pKa = 10.15QEE136 pKa = 3.59EE137 pKa = 4.54TMNLKK142 pKa = 8.49TAMWILANLIPRR154 pKa = 11.84DD155 pKa = 4.0MLSLTGDD162 pKa = 4.77LLPSLWGSGLLMLKK176 pKa = 9.76LQKK179 pKa = 10.13EE180 pKa = 4.71GRR182 pKa = 11.84STSSS186 pKa = 2.66

Molecular weight: 21.11 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

4903

186

2183

700.4

78.24

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.078 ± 0.533

1.652 ± 0.299

5.425 ± 0.342

5.466 ± 0.437

3.161 ± 0.475

6.771 ± 0.695

2.284 ± 0.473

7.281 ± 0.418

5.099 ± 0.365

10.891 ± 0.43

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.549 ± 0.196

4.242 ± 0.244

4.691 ± 0.369

3.528 ± 0.388

6.078 ± 0.286

8.423 ± 0.401

5.548 ± 0.147

6.282 ± 0.542

1.081 ± 0.196

3.467 ± 0.448
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski