Amino acid dipepetide frequency for Measles virus (strain Edmonston-AIK-C vaccine) (MeV) (Subacute sclerose panencephalitis virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.284AlaAla: 4.284 ± 0.687
1.02AlaCys: 1.02 ± 0.502
2.652AlaAsp: 2.652 ± 0.769
3.672AlaGlu: 3.672 ± 1.1
2.04AlaPhe: 2.04 ± 0.789
3.876AlaGly: 3.876 ± 1.327
1.224AlaHis: 1.224 ± 0.479
4.08AlaIle: 4.08 ± 1.076
2.856AlaLys: 2.856 ± 0.336
7.548AlaLeu: 7.548 ± 1.15
1.836AlaMet: 1.836 ± 0.9
2.244AlaAsn: 2.244 ± 0.648
2.856AlaPro: 2.856 ± 0.826
1.428AlaGln: 1.428 ± 0.48
4.08AlaArg: 4.08 ± 1.168
5.304AlaSer: 5.304 ± 1.97
2.04AlaThr: 2.04 ± 0.808
5.1AlaVal: 5.1 ± 1.569
0.612AlaTrp: 0.612 ± 0.363
2.04AlaTyr: 2.04 ± 0.901
0.0AlaXaa: 0.0 ± 0.0
Cys
1.224CysAla: 1.224 ± 0.434
0.612CysCys: 0.612 ± 0.481
0.612CysAsp: 0.612 ± 0.315
0.612CysGlu: 0.612 ± 0.286
1.428CysPhe: 1.428 ± 0.51
0.816CysGly: 0.816 ± 0.527
0.612CysHis: 0.612 ± 0.424
0.816CysIle: 0.816 ± 0.321
1.02CysLys: 1.02 ± 0.63
1.224CysLeu: 1.224 ± 0.461
0.204CysMet: 0.204 ± 0.224
0.816CysAsn: 0.816 ± 0.342
0.612CysPro: 0.612 ± 0.273
1.02CysGln: 1.02 ± 0.659
0.612CysArg: 0.612 ± 0.413
1.02CysSer: 1.02 ± 0.306
0.816CysThr: 0.816 ± 0.453
1.428CysVal: 1.428 ± 0.75
0.0CysTrp: 0.0 ± 0.0
1.02CysTyr: 1.02 ± 0.374
0.0CysXaa: 0.0 ± 0.0
Asp
2.448AspAla: 2.448 ± 0.844
0.612AspCys: 0.612 ± 0.286
3.672AspAsp: 3.672 ± 0.79
2.244AspGlu: 2.244 ± 0.278
0.612AspPhe: 0.612 ± 0.318
1.632AspGly: 1.632 ± 0.482
1.632AspHis: 1.632 ± 0.609
4.08AspIle: 4.08 ± 0.866
2.856AspLys: 2.856 ± 0.642
6.324AspLeu: 6.324 ± 0.95
1.02AspMet: 1.02 ± 0.335
3.264AspAsn: 3.264 ± 0.799
4.284AspPro: 4.284 ± 0.837
2.244AspGln: 2.244 ± 0.712
3.468AspArg: 3.468 ± 0.815
3.468AspSer: 3.468 ± 0.666
3.672AspThr: 3.672 ± 0.876
4.896AspVal: 4.896 ± 0.78
0.408AspTrp: 0.408 ± 0.256
1.428AspTyr: 1.428 ± 0.299
0.0AspXaa: 0.0 ± 0.0
Glu
3.06GluAla: 3.06 ± 0.511
1.02GluCys: 1.02 ± 0.441
3.876GluAsp: 3.876 ± 0.947
2.856GluGlu: 2.856 ± 1.052
2.04GluPhe: 2.04 ± 0.56
3.06GluGly: 3.06 ± 1.048
1.02GluHis: 1.02 ± 0.638
4.488GluIle: 4.488 ± 0.802
2.856GluLys: 2.856 ± 0.826
6.528GluLeu: 6.528 ± 1.235
0.816GluMet: 0.816 ± 0.522
1.836GluAsn: 1.836 ± 0.873
2.04GluPro: 2.04 ± 0.688
1.632GluGln: 1.632 ± 0.2
1.632GluArg: 1.632 ± 0.51
5.304GluSer: 5.304 ± 1.106
5.1GluThr: 5.1 ± 1.341
3.264GluVal: 3.264 ± 0.412
1.428GluTrp: 1.428 ± 0.383
0.816GluTyr: 0.816 ± 0.321
0.0GluXaa: 0.0 ± 0.0
Phe
1.428PheAla: 1.428 ± 0.48
0.408PheCys: 0.408 ± 0.22
1.428PheAsp: 1.428 ± 0.384
1.02PheGlu: 1.02 ± 0.375
1.224PhePhe: 1.224 ± 0.791
2.04PheGly: 2.04 ± 0.757
0.816PheHis: 0.816 ± 0.303
3.06PheIle: 3.06 ± 1.331
1.836PheLys: 1.836 ± 0.563
2.856PheLeu: 2.856 ± 1.201
1.428PheMet: 1.428 ± 0.912
1.836PheAsn: 1.836 ± 0.567
0.612PhePro: 0.612 ± 0.266
1.02PheGln: 1.02 ± 0.462
2.856PheArg: 2.856 ± 1.013
1.836PheSer: 1.836 ± 0.529
1.632PheThr: 1.632 ± 0.774
2.652PheVal: 2.652 ± 1.074
0.816PheTrp: 0.816 ± 0.527
0.816PheTyr: 0.816 ± 0.474
0.0PheXaa: 0.0 ± 0.0
Gly
2.448GlyAla: 2.448 ± 0.789
0.408GlyCys: 0.408 ± 0.264
3.876GlyAsp: 3.876 ± 0.317
3.468GlyGlu: 3.468 ± 1.132
2.856GlyPhe: 2.856 ± 0.749
4.488GlyGly: 4.488 ± 0.983
1.632GlyHis: 1.632 ± 0.663
3.876GlyIle: 3.876 ± 1.389
2.652GlyLys: 2.652 ± 0.941
8.364GlyLeu: 8.364 ± 0.76
2.448GlyMet: 2.448 ± 0.801
3.264GlyAsn: 3.264 ± 0.729
3.06GlyPro: 3.06 ± 0.97
2.856GlyGln: 2.856 ± 0.922
3.468GlyArg: 3.468 ± 1.068
6.936GlySer: 6.936 ± 0.576
3.468GlyThr: 3.468 ± 1.288
5.508GlyVal: 5.508 ± 1.671
0.408GlyTrp: 0.408 ± 0.245
2.244GlyTyr: 2.244 ± 0.431
0.0GlyXaa: 0.0 ± 0.0
His
1.836HisAla: 1.836 ± 0.539
0.816HisCys: 0.816 ± 0.359
1.632HisAsp: 1.632 ± 0.873
1.428HisGlu: 1.428 ± 0.455
0.408HisPhe: 0.408 ± 0.22
1.02HisGly: 1.02 ± 0.335
0.408HisHis: 0.408 ± 0.264
2.244HisIle: 2.244 ± 0.701
0.612HisLys: 0.612 ± 0.239
2.244HisLeu: 2.244 ± 0.621
0.612HisMet: 0.612 ± 0.286
0.408HisAsn: 0.408 ± 0.22
1.02HisPro: 1.02 ± 0.502
1.428HisGln: 1.428 ± 0.499
2.448HisArg: 2.448 ± 0.747
1.428HisSer: 1.428 ± 0.548
1.224HisThr: 1.224 ± 0.623
0.816HisVal: 0.816 ± 0.279
0.408HisTrp: 0.408 ± 0.406
0.408HisTyr: 0.408 ± 0.264
0.0HisXaa: 0.0 ± 0.0
Ile
5.1IleAla: 5.1 ± 1.326
0.612IleCys: 0.612 ± 0.315
3.264IleAsp: 3.264 ± 0.7
3.672IleGlu: 3.672 ± 0.798
1.428IlePhe: 1.428 ± 0.707
5.916IleGly: 5.916 ± 1.256
2.244IleHis: 2.244 ± 0.641
3.876IleIle: 3.876 ± 0.666
6.324IleLys: 6.324 ± 0.768
6.324IleLeu: 6.324 ± 2.131
1.224IleMet: 1.224 ± 0.75
4.692IleAsn: 4.692 ± 0.835
3.672IlePro: 3.672 ± 0.508
2.652IleGln: 2.652 ± 0.62
4.284IleArg: 4.284 ± 0.386
6.324IleSer: 6.324 ± 1.162
4.692IleThr: 4.692 ± 0.63
4.284IleVal: 4.284 ± 0.806
0.204IleTrp: 0.204 ± 0.254
2.04IleTyr: 2.04 ± 0.789
0.0IleXaa: 0.0 ± 0.0
Lys
2.652LysAla: 2.652 ± 0.49
0.612LysCys: 0.612 ± 0.273
3.264LysAsp: 3.264 ± 0.94
4.488LysGlu: 4.488 ± 1.273
2.04LysPhe: 2.04 ± 0.567
4.488LysGly: 4.488 ± 1.041
0.816LysHis: 0.816 ± 0.393
4.08LysIle: 4.08 ± 1.109
2.652LysLys: 2.652 ± 0.964
6.528LysLeu: 6.528 ± 0.919
1.632LysMet: 1.632 ± 1.071
1.02LysAsn: 1.02 ± 0.356
1.836LysPro: 1.836 ± 1.189
1.224LysGln: 1.224 ± 0.404
2.652LysArg: 2.652 ± 0.532
3.468LysSer: 3.468 ± 0.633
1.632LysThr: 1.632 ± 1.0
3.468LysVal: 3.468 ± 0.848
0.408LysTrp: 0.408 ± 0.327
2.04LysTyr: 2.04 ± 0.668
0.0LysXaa: 0.0 ± 0.0
Leu
8.364LeuAla: 8.364 ± 1.388
1.836LeuCys: 1.836 ± 0.459
5.304LeuAsp: 5.304 ± 0.798
7.344LeuGlu: 7.344 ± 1.339
3.672LeuPhe: 3.672 ± 0.69
7.956LeuGly: 7.956 ± 2.059
3.468LeuHis: 3.468 ± 0.787
8.16LeuIle: 8.16 ± 1.94
7.344LeuLys: 7.344 ± 1.511
10.812LeuLeu: 10.812 ± 1.436
3.672LeuMet: 3.672 ± 0.577
3.672LeuAsn: 3.672 ± 0.695
2.652LeuPro: 2.652 ± 0.713
2.652LeuGln: 2.652 ± 1.149
6.324LeuArg: 6.324 ± 1.236
9.384LeuSer: 9.384 ± 1.9
5.712LeuThr: 5.712 ± 0.628
6.12LeuVal: 6.12 ± 1.373
1.428LeuTrp: 1.428 ± 0.931
3.06LeuTyr: 3.06 ± 1.05
0.0LeuXaa: 0.0 ± 0.0
Met
1.836MetAla: 1.836 ± 0.458
0.0MetCys: 0.0 ± 0.0
0.816MetAsp: 0.816 ± 0.312
0.612MetGlu: 0.612 ± 0.289
0.612MetPhe: 0.612 ± 0.285
2.04MetGly: 2.04 ± 0.573
0.408MetHis: 0.408 ± 0.245
2.04MetIle: 2.04 ± 0.376
1.428MetLys: 1.428 ± 0.54
2.244MetLeu: 2.244 ± 0.848
0.0MetMet: 0.0 ± 0.0
1.632MetAsn: 1.632 ± 0.334
1.02MetPro: 1.02 ± 0.49
0.204MetGln: 0.204 ± 0.224
0.816MetArg: 0.816 ± 0.527
2.448MetSer: 2.448 ± 1.018
3.264MetThr: 3.264 ± 0.491
2.04MetVal: 2.04 ± 0.786
0.612MetTrp: 0.612 ± 0.298
1.428MetTyr: 1.428 ± 0.425
0.0MetXaa: 0.0 ± 0.0
Asn
2.652AsnAla: 2.652 ± 1.144
1.224AsnCys: 1.224 ± 0.479
1.836AsnAsp: 1.836 ± 0.395
2.244AsnGlu: 2.244 ± 0.539
1.428AsnPhe: 1.428 ± 0.286
2.244AsnGly: 2.244 ± 0.631
0.612AsnHis: 0.612 ± 0.285
3.06AsnIle: 3.06 ± 1.169
2.04AsnLys: 2.04 ± 0.995
5.916AsnLeu: 5.916 ± 0.568
1.428AsnMet: 1.428 ± 0.565
1.836AsnAsn: 1.836 ± 0.575
2.856AsnPro: 2.856 ± 1.057
2.652AsnGln: 2.652 ± 0.582
2.04AsnArg: 2.04 ± 0.508
2.856AsnSer: 2.856 ± 0.642
1.02AsnThr: 1.02 ± 0.555
2.856AsnVal: 2.856 ± 0.795
0.612AsnTrp: 0.612 ± 0.395
1.02AsnTyr: 1.02 ± 0.502
0.0AsnXaa: 0.0 ± 0.0
Pro
2.244ProAla: 2.244 ± 0.44
0.204ProCys: 0.204 ± 0.26
2.856ProAsp: 2.856 ± 1.101
2.856ProGlu: 2.856 ± 0.439
0.612ProPhe: 0.612 ± 0.286
3.672ProGly: 3.672 ± 1.097
0.816ProHis: 0.816 ± 0.387
5.304ProIle: 5.304 ± 0.845
2.448ProLys: 2.448 ± 0.514
3.876ProLeu: 3.876 ± 1.211
1.02ProMet: 1.02 ± 0.306
1.428ProAsn: 1.428 ± 0.331
3.06ProPro: 3.06 ± 0.823
1.836ProGln: 1.836 ± 0.952
2.856ProArg: 2.856 ± 0.713
4.08ProSer: 4.08 ± 0.926
2.652ProThr: 2.652 ± 0.653
2.448ProVal: 2.448 ± 0.595
0.204ProTrp: 0.204 ± 0.313
2.448ProTyr: 2.448 ± 0.797
0.0ProXaa: 0.0 ± 0.0
Gln
3.672GlnAla: 3.672 ± 1.366
1.02GlnCys: 1.02 ± 0.477
2.652GlnAsp: 2.652 ± 0.68
1.836GlnGlu: 1.836 ± 1.317
0.612GlnPhe: 0.612 ± 0.424
2.652GlnGly: 2.652 ± 0.614
0.408GlnHis: 0.408 ± 0.256
2.448GlnIle: 2.448 ± 0.727
1.224GlnLys: 1.224 ± 0.634
3.06GlnLeu: 3.06 ± 0.731
0.816GlnMet: 0.816 ± 0.256
2.04GlnAsn: 2.04 ± 0.492
1.632GlnPro: 1.632 ± 0.559
1.836GlnGln: 1.836 ± 0.597
2.244GlnArg: 2.244 ± 0.622
3.06GlnSer: 3.06 ± 1.452
0.816GlnThr: 0.816 ± 0.334
2.448GlnVal: 2.448 ± 0.509
0.408GlnTrp: 0.408 ± 0.264
0.408GlnTyr: 0.408 ± 0.448
0.0GlnXaa: 0.0 ± 0.0
Arg
4.488ArgAla: 4.488 ± 0.83
0.816ArgCys: 0.816 ± 0.342
3.06ArgAsp: 3.06 ± 0.615
3.672ArgGlu: 3.672 ± 1.017
2.04ArgPhe: 2.04 ± 0.54
4.284ArgGly: 4.284 ± 0.739
1.836ArgHis: 1.836 ± 0.372
3.672ArgIle: 3.672 ± 0.935
2.856ArgLys: 2.856 ± 0.87
8.568ArgLeu: 8.568 ± 1.458
1.428ArgMet: 1.428 ± 0.497
1.836ArgAsn: 1.836 ± 0.642
1.836ArgPro: 1.836 ± 0.489
1.836ArgGln: 1.836 ± 0.436
4.896ArgArg: 4.896 ± 1.261
5.916ArgSer: 5.916 ± 1.175
2.04ArgThr: 2.04 ± 0.66
3.468ArgVal: 3.468 ± 0.639
0.204ArgTrp: 0.204 ± 0.254
2.04ArgTyr: 2.04 ± 0.718
0.0ArgXaa: 0.0 ± 0.0
Ser
4.284SerAla: 4.284 ± 1.22
1.428SerCys: 1.428 ± 0.632
4.692SerAsp: 4.692 ± 1.156
3.672SerGlu: 3.672 ± 1.338
3.06SerPhe: 3.06 ± 0.748
7.548SerGly: 7.548 ± 1.513
1.836SerHis: 1.836 ± 0.578
5.304SerIle: 5.304 ± 0.713
3.468SerLys: 3.468 ± 0.581
8.16SerLeu: 8.16 ± 0.351
2.244SerMet: 2.244 ± 0.544
3.468SerAsn: 3.468 ± 1.196
3.06SerPro: 3.06 ± 0.766
3.264SerGln: 3.264 ± 0.722
7.344SerArg: 7.344 ± 1.281
7.344SerSer: 7.344 ± 0.943
5.712SerThr: 5.712 ± 0.703
3.672SerVal: 3.672 ± 1.005
1.224SerTrp: 1.224 ± 0.446
3.264SerTyr: 3.264 ± 1.288
0.0SerXaa: 0.0 ± 0.0
Thr
3.876ThrAla: 3.876 ± 1.385
1.224ThrCys: 1.224 ± 0.27
3.264ThrAsp: 3.264 ± 0.88
3.264ThrGlu: 3.264 ± 1.076
1.02ThrPhe: 1.02 ± 0.35
4.08ThrGly: 4.08 ± 0.811
1.02ThrHis: 1.02 ± 0.377
4.08ThrIle: 4.08 ± 0.969
1.224ThrLys: 1.224 ± 0.585
6.12ThrLeu: 6.12 ± 1.426
1.224ThrMet: 1.224 ± 0.359
3.06ThrAsn: 3.06 ± 0.84
3.06ThrPro: 3.06 ± 0.89
1.632ThrGln: 1.632 ± 0.501
3.264ThrArg: 3.264 ± 0.691
3.672ThrSer: 3.672 ± 0.551
4.08ThrThr: 4.08 ± 0.666
2.652ThrVal: 2.652 ± 0.663
1.02ThrTrp: 1.02 ± 0.493
2.652ThrTyr: 2.652 ± 0.605
0.0ThrXaa: 0.0 ± 0.0
Val
2.856ValAla: 2.856 ± 0.424
1.02ValCys: 1.02 ± 0.53
2.244ValAsp: 2.244 ± 0.654
4.284ValGlu: 4.284 ± 0.574
2.244ValPhe: 2.244 ± 0.872
4.08ValGly: 4.08 ± 0.657
1.224ValHis: 1.224 ± 0.436
6.324ValIle: 6.324 ± 1.463
2.856ValLys: 2.856 ± 0.817
6.732ValLeu: 6.732 ± 1.162
0.816ValMet: 0.816 ± 0.241
2.244ValAsn: 2.244 ± 0.533
4.08ValPro: 4.08 ± 0.771
2.244ValGln: 2.244 ± 0.724
3.672ValArg: 3.672 ± 1.073
5.916ValSer: 5.916 ± 1.188
3.468ValThr: 3.468 ± 0.961
2.856ValVal: 2.856 ± 1.073
0.204ValTrp: 0.204 ± 0.224
3.468ValTyr: 3.468 ± 0.452
0.0ValXaa: 0.0 ± 0.0
Trp
1.224TrpAla: 1.224 ± 0.572
0.408TrpCys: 0.408 ± 0.448
0.612TrpAsp: 0.612 ± 0.318
0.204TrpGlu: 0.204 ± 0.278
1.02TrpPhe: 1.02 ± 0.399
0.612TrpGly: 0.612 ± 0.347
0.204TrpHis: 0.204 ± 0.132
0.612TrpIle: 0.612 ± 0.427
0.612TrpLys: 0.612 ± 0.286
0.816TrpLeu: 0.816 ± 0.308
0.0TrpMet: 0.0 ± 0.0
0.612TrpAsn: 0.612 ± 0.298
0.612TrpPro: 0.612 ± 0.298
0.204TrpGln: 0.204 ± 0.278
0.612TrpArg: 0.612 ± 0.578
0.816TrpSer: 0.816 ± 0.256
0.408TrpThr: 0.408 ± 0.227
0.816TrpVal: 0.816 ± 0.308
0.0TrpTrp: 0.0 ± 0.0
0.408TrpTyr: 0.408 ± 0.234
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.816TyrAla: 0.816 ± 0.332
1.224TyrCys: 1.224 ± 0.439
2.652TyrAsp: 2.652 ± 0.798
1.224TyrGlu: 1.224 ± 0.791
1.224TyrPhe: 1.224 ± 0.712
1.224TyrGly: 1.224 ± 0.572
0.612TyrHis: 0.612 ± 0.395
1.224TyrIle: 1.224 ± 0.727
1.836TyrLys: 1.836 ± 0.645
4.692TyrLeu: 4.692 ± 1.345
1.428TyrMet: 1.428 ± 0.561
1.224TyrAsn: 1.224 ± 0.302
3.06TyrPro: 3.06 ± 0.7
1.428TyrGln: 1.428 ± 0.522
1.224TyrArg: 1.224 ± 0.293
3.672TyrSer: 3.672 ± 1.265
2.04TyrThr: 2.04 ± 0.601
2.04TyrVal: 2.04 ± 0.696
0.204TyrTrp: 0.204 ± 0.224
1.632TyrTyr: 1.632 ± 0.472
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (4903 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski