Amino acid dipepetide frequency for Turnip curly top virus (isolate Turnip/South Africa/B11/2006)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.639AlaAla: 2.639 ± 1.114
0.88AlaCys: 0.88 ± 0.624
0.0AlaAsp: 0.0 ± 0.0
3.518AlaGlu: 3.518 ± 1.052
2.639AlaPhe: 2.639 ± 1.446
1.759AlaGly: 1.759 ± 0.681
0.88AlaHis: 0.88 ± 0.683
0.88AlaIle: 0.88 ± 0.624
2.639AlaLys: 2.639 ± 1.32
6.157AlaLeu: 6.157 ± 1.959
0.88AlaMet: 0.88 ± 1.013
1.759AlaAsn: 1.759 ± 0.681
4.398AlaPro: 4.398 ± 2.096
1.759AlaGln: 1.759 ± 0.681
4.398AlaArg: 4.398 ± 1.525
2.639AlaSer: 2.639 ± 1.002
2.639AlaThr: 2.639 ± 1.36
1.759AlaVal: 1.759 ± 0.681
0.88AlaTrp: 0.88 ± 1.013
1.759AlaTyr: 1.759 ± 1.857
0.0AlaXaa: 0.0 ± 0.0
Cys
0.88CysAla: 0.88 ± 0.624
0.0CysCys: 0.0 ± 0.0
0.88CysAsp: 0.88 ± 0.683
0.88CysGlu: 0.88 ± 0.928
0.0CysPhe: 0.0 ± 0.0
0.88CysGly: 0.88 ± 0.78
1.759CysHis: 1.759 ± 1.249
0.88CysIle: 0.88 ± 0.683
1.759CysLys: 1.759 ± 1.561
0.88CysLeu: 0.88 ± 1.02
0.0CysMet: 0.0 ± 0.0
0.88CysAsn: 0.88 ± 0.624
0.88CysPro: 0.88 ± 0.624
0.0CysGln: 0.0 ± 0.0
0.88CysArg: 0.88 ± 0.624
0.0CysSer: 0.0 ± 0.0
0.88CysThr: 0.88 ± 0.683
0.0CysVal: 0.0 ± 0.0
0.88CysTrp: 0.88 ± 0.928
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.518AspAla: 3.518 ± 1.673
0.88AspCys: 0.88 ± 0.683
4.398AspAsp: 4.398 ± 1.771
1.759AspGlu: 1.759 ± 1.857
2.639AspPhe: 2.639 ± 1.045
2.639AspGly: 2.639 ± 1.873
0.88AspHis: 0.88 ± 1.013
1.759AspIle: 1.759 ± 0.681
2.639AspLys: 2.639 ± 0.818
5.277AspLeu: 5.277 ± 1.824
0.88AspMet: 0.88 ± 0.683
3.518AspAsn: 3.518 ± 1.847
1.759AspPro: 1.759 ± 0.681
1.759AspGln: 1.759 ± 0.681
1.759AspArg: 1.759 ± 0.799
1.759AspSer: 1.759 ± 0.681
1.759AspThr: 1.759 ± 1.005
2.639AspVal: 2.639 ± 1.873
3.518AspTrp: 3.518 ± 1.598
2.639AspTyr: 2.639 ± 1.114
0.0AspXaa: 0.0 ± 0.0
Glu
5.277GluAla: 5.277 ± 1.89
0.88GluCys: 0.88 ± 0.78
3.518GluAsp: 3.518 ± 1.052
7.036GluGlu: 7.036 ± 2.753
5.277GluPhe: 5.277 ± 1.75
2.639GluGly: 2.639 ± 1.203
0.88GluHis: 0.88 ± 0.683
1.759GluIle: 1.759 ± 1.339
4.398GluLys: 4.398 ± 1.225
0.88GluLeu: 0.88 ± 1.02
0.88GluMet: 0.88 ± 1.02
1.759GluAsn: 1.759 ± 0.96
2.639GluPro: 2.639 ± 1.264
0.0GluGln: 0.0 ± 0.0
1.759GluArg: 1.759 ± 0.799
4.398GluSer: 4.398 ± 0.86
3.518GluThr: 3.518 ± 3.023
4.398GluVal: 4.398 ± 1.995
2.639GluTrp: 2.639 ± 0.818
2.639GluTyr: 2.639 ± 1.277
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
2.639PheAsp: 2.639 ± 0.675
1.759PheGlu: 1.759 ± 0.799
2.639PhePhe: 2.639 ± 1.045
0.88PheGly: 0.88 ± 0.683
1.759PheHis: 1.759 ± 0.96
2.639PheIle: 2.639 ± 1.213
2.639PheLys: 2.639 ± 2.081
4.398PheLeu: 4.398 ± 1.607
0.88PheMet: 0.88 ± 0.928
6.157PheAsn: 6.157 ± 2.236
2.639PhePro: 2.639 ± 2.049
2.639PheGln: 2.639 ± 1.32
3.518PheArg: 3.518 ± 2.183
3.518PheSer: 3.518 ± 1.847
4.398PheThr: 4.398 ± 2.215
1.759PheVal: 1.759 ± 0.96
0.88PheTrp: 0.88 ± 0.683
2.639PheTyr: 2.639 ± 2.081
0.0PheXaa: 0.0 ± 0.0
Gly
3.518GlyAla: 3.518 ± 1.673
0.0GlyCys: 0.0 ± 0.0
3.518GlyAsp: 3.518 ± 1.363
7.036GlyGlu: 7.036 ± 1.834
1.759GlyPhe: 1.759 ± 1.247
6.157GlyGly: 6.157 ± 1.752
1.759GlyHis: 1.759 ± 0.96
5.277GlyIle: 5.277 ± 2.07
3.518GlyLys: 3.518 ± 1.673
1.759GlyLeu: 1.759 ± 1.247
0.0GlyMet: 0.0 ± 0.0
1.759GlyAsn: 1.759 ± 1.109
3.518GlyPro: 3.518 ± 0.934
1.759GlyGln: 1.759 ± 0.681
2.639GlyArg: 2.639 ± 0.952
2.639GlySer: 2.639 ± 1.203
4.398GlyThr: 4.398 ± 1.217
3.518GlyVal: 3.518 ± 1.609
0.88GlyTrp: 0.88 ± 0.683
1.759GlyTyr: 1.759 ± 0.681
0.0GlyXaa: 0.0 ± 0.0
His
0.88HisAla: 0.88 ± 0.624
0.88HisCys: 0.88 ± 0.624
1.759HisAsp: 1.759 ± 1.099
1.759HisGlu: 1.759 ± 1.339
1.759HisPhe: 1.759 ± 0.681
1.759HisGly: 1.759 ± 1.561
0.88HisHis: 0.88 ± 0.78
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
5.277HisLeu: 5.277 ± 2.116
1.759HisMet: 1.759 ± 1.184
2.639HisAsn: 2.639 ± 1.203
0.88HisPro: 0.88 ± 0.624
2.639HisGln: 2.639 ± 2.134
3.518HisArg: 3.518 ± 3.099
0.88HisSer: 0.88 ± 0.683
1.759HisThr: 1.759 ± 0.799
2.639HisVal: 2.639 ± 1.184
0.88HisTrp: 0.88 ± 0.624
1.759HisTyr: 1.759 ± 0.681
0.0HisXaa: 0.0 ± 0.0
Ile
0.88IleAla: 0.88 ± 0.928
2.639IleCys: 2.639 ± 1.114
3.518IleAsp: 3.518 ± 2.498
3.518IleGlu: 3.518 ± 1.748
5.277IlePhe: 5.277 ± 1.419
4.398IleGly: 4.398 ± 1.217
4.398IleHis: 4.398 ± 2.255
5.277IleIle: 5.277 ± 2.025
1.759IleLys: 1.759 ± 0.799
4.398IleLeu: 4.398 ± 1.642
0.88IleMet: 0.88 ± 0.78
3.518IleAsn: 3.518 ± 2.141
1.759IlePro: 1.759 ± 1.249
5.277IleGln: 5.277 ± 2.406
3.518IleArg: 3.518 ± 1.091
6.157IleSer: 6.157 ± 4.044
7.036IleThr: 7.036 ± 2.852
0.88IleVal: 0.88 ± 0.683
1.759IleTrp: 1.759 ± 1.005
2.639IleTyr: 2.639 ± 1.313
0.0IleXaa: 0.0 ± 0.0
Lys
2.639LysAla: 2.639 ± 2.049
1.759LysCys: 1.759 ± 1.315
6.157LysAsp: 6.157 ± 1.379
6.157LysGlu: 6.157 ± 1.464
4.398LysPhe: 4.398 ± 1.217
2.639LysGly: 2.639 ± 1.213
1.759LysHis: 1.759 ± 1.249
2.639LysIle: 2.639 ± 0.675
4.398LysLys: 4.398 ± 1.161
2.639LysLeu: 2.639 ± 0.952
0.88LysMet: 0.88 ± 0.624
0.88LysAsn: 0.88 ± 0.624
7.036LysPro: 7.036 ± 1.704
1.759LysGln: 1.759 ± 1.184
5.277LysArg: 5.277 ± 2.421
6.157LysSer: 6.157 ± 2.015
4.398LysThr: 4.398 ± 1.7
1.759LysVal: 1.759 ± 1.249
0.0LysTrp: 0.0 ± 0.0
3.518LysTyr: 3.518 ± 1.673
0.0LysXaa: 0.0 ± 0.0
Leu
5.277LeuAla: 5.277 ± 2.451
0.88LeuCys: 0.88 ± 0.624
4.398LeuAsp: 4.398 ± 1.438
1.759LeuGlu: 1.759 ± 1.249
4.398LeuPhe: 4.398 ± 1.724
3.518LeuGly: 3.518 ± 2.853
2.639LeuHis: 2.639 ± 1.184
3.518LeuIle: 3.518 ± 1.362
10.554LeuLys: 10.554 ± 1.947
5.277LeuLeu: 5.277 ± 1.534
2.639LeuMet: 2.639 ± 1.534
4.398LeuAsn: 4.398 ± 1.807
3.518LeuPro: 3.518 ± 1.773
5.277LeuGln: 5.277 ± 1.78
6.157LeuArg: 6.157 ± 2.86
5.277LeuSer: 5.277 ± 3.646
3.518LeuThr: 3.518 ± 1.748
0.88LeuVal: 0.88 ± 1.013
0.88LeuTrp: 0.88 ± 0.624
1.759LeuTyr: 1.759 ± 0.681
0.0LeuXaa: 0.0 ± 0.0
Met
1.759MetAla: 1.759 ± 1.184
0.88MetCys: 0.88 ± 1.02
0.0MetAsp: 0.0 ± 0.0
1.759MetGlu: 1.759 ± 1.109
0.0MetPhe: 0.0 ± 0.0
1.759MetGly: 1.759 ± 1.339
2.639MetHis: 2.639 ± 2.018
0.88MetIle: 0.88 ± 0.928
3.518MetLys: 3.518 ± 0.905
1.759MetLeu: 1.759 ± 1.005
0.88MetMet: 0.88 ± 1.02
0.0MetAsn: 0.0 ± 0.0
0.88MetPro: 0.88 ± 0.624
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.759MetSer: 1.759 ± 1.184
1.759MetThr: 1.759 ± 1.366
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
3.518MetTyr: 3.518 ± 2.733
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
4.398AsnAsp: 4.398 ± 1.109
0.88AsnGlu: 0.88 ± 0.624
2.639AsnPhe: 2.639 ± 1.468
4.398AsnGly: 4.398 ± 2.057
0.88AsnHis: 0.88 ± 0.624
6.157AsnIle: 6.157 ± 1.362
1.759AsnLys: 1.759 ± 1.366
7.916AsnLeu: 7.916 ± 2.362
0.0AsnMet: 0.0 ± 0.0
2.639AsnAsn: 2.639 ± 1.647
3.518AsnPro: 3.518 ± 1.748
1.759AsnGln: 1.759 ± 1.184
2.639AsnArg: 2.639 ± 2.018
4.398AsnSer: 4.398 ± 1.885
0.0AsnThr: 0.0 ± 0.0
2.639AsnVal: 2.639 ± 0.818
0.0AsnTrp: 0.0 ± 0.0
4.398AsnTyr: 4.398 ± 1.918
0.0AsnXaa: 0.0 ± 0.0
Pro
2.639ProAla: 2.639 ± 0.818
0.88ProCys: 0.88 ± 0.78
0.0ProAsp: 0.0 ± 0.0
2.639ProGlu: 2.639 ± 1.191
1.759ProPhe: 1.759 ± 1.253
4.398ProGly: 4.398 ± 1.468
2.639ProHis: 2.639 ± 1.873
3.518ProIle: 3.518 ± 1.498
4.398ProLys: 4.398 ± 1.739
2.639ProLeu: 2.639 ± 1.191
0.88ProMet: 0.88 ± 0.732
4.398ProAsn: 4.398 ± 1.311
2.639ProPro: 2.639 ± 1.203
0.0ProGln: 0.0 ± 0.0
4.398ProArg: 4.398 ± 2.267
7.036ProSer: 7.036 ± 2.84
2.639ProThr: 2.639 ± 1.264
7.916ProVal: 7.916 ± 2.628
0.0ProTrp: 0.0 ± 0.0
0.88ProTyr: 0.88 ± 0.683
0.0ProXaa: 0.0 ± 0.0
Gln
0.88GlnAla: 0.88 ± 0.683
0.88GlnCys: 0.88 ± 0.624
0.0GlnAsp: 0.0 ± 0.0
2.639GlnGlu: 2.639 ± 1.872
4.398GlnPhe: 4.398 ± 1.739
0.88GlnGly: 0.88 ± 0.624
0.88GlnHis: 0.88 ± 0.78
4.398GlnIle: 4.398 ± 1.295
0.88GlnLys: 0.88 ± 0.624
4.398GlnLeu: 4.398 ± 1.849
0.0GlnMet: 0.0 ± 0.0
2.639GlnAsn: 2.639 ± 1.114
1.759GlnPro: 1.759 ± 0.905
2.639GlnGln: 2.639 ± 1.191
1.759GlnArg: 1.759 ± 1.109
4.398GlnSer: 4.398 ± 2.674
3.518GlnThr: 3.518 ± 1.743
0.88GlnVal: 0.88 ± 1.013
0.88GlnTrp: 0.88 ± 0.683
0.88GlnTyr: 0.88 ± 0.624
0.0GlnXaa: 0.0 ± 0.0
Arg
2.639ArgAla: 2.639 ± 1.36
0.0ArgCys: 0.0 ± 0.0
4.398ArgAsp: 4.398 ± 1.918
2.639ArgGlu: 2.639 ± 1.468
3.518ArgPhe: 3.518 ± 2.074
3.518ArgGly: 3.518 ± 1.098
2.639ArgHis: 2.639 ± 1.264
6.157ArgIle: 6.157 ± 2.579
2.639ArgLys: 2.639 ± 1.647
5.277ArgLeu: 5.277 ± 3.248
0.88ArgMet: 0.88 ± 1.034
1.759ArgAsn: 1.759 ± 0.905
2.639ArgPro: 2.639 ± 1.213
1.759ArgGln: 1.759 ± 0.96
6.157ArgArg: 6.157 ± 3.346
4.398ArgSer: 4.398 ± 1.083
4.398ArgThr: 4.398 ± 1.341
4.398ArgVal: 4.398 ± 1.977
1.759ArgTrp: 1.759 ± 1.366
1.759ArgTyr: 1.759 ± 1.005
0.0ArgXaa: 0.0 ± 0.0
Ser
1.759SerAla: 1.759 ± 1.099
0.88SerCys: 0.88 ± 0.928
3.518SerAsp: 3.518 ± 1.363
1.759SerGlu: 1.759 ± 1.005
1.759SerPhe: 1.759 ± 1.005
3.518SerGly: 3.518 ± 1.363
1.759SerHis: 1.759 ± 0.96
7.036SerIle: 7.036 ± 3.07
3.518SerLys: 3.518 ± 1.067
5.277SerLeu: 5.277 ± 1.557
2.639SerMet: 2.639 ± 2.018
2.639SerAsn: 2.639 ± 1.468
6.157SerPro: 6.157 ± 2.409
1.759SerGln: 1.759 ± 1.561
6.157SerArg: 6.157 ± 1.784
13.193SerSer: 13.193 ± 7.013
7.036SerThr: 7.036 ± 0.943
5.277SerVal: 5.277 ± 1.866
2.639SerTrp: 2.639 ± 0.952
2.639SerTyr: 2.639 ± 1.873
0.0SerXaa: 0.0 ± 0.0
Thr
3.518ThrAla: 3.518 ± 1.363
0.0ThrCys: 0.0 ± 0.0
1.759ThrAsp: 1.759 ± 0.955
3.518ThrGlu: 3.518 ± 1.613
1.759ThrPhe: 1.759 ± 1.366
7.916ThrGly: 7.916 ± 1.818
4.398ThrHis: 4.398 ± 2.755
4.398ThrIle: 4.398 ± 1.849
4.398ThrLys: 4.398 ± 1.438
1.759ThrLeu: 1.759 ± 0.799
3.518ThrMet: 3.518 ± 2.025
1.759ThrAsn: 1.759 ± 0.799
5.277ThrPro: 5.277 ± 1.237
2.639ThrGln: 2.639 ± 1.002
0.88ThrArg: 0.88 ± 0.928
4.398ThrSer: 4.398 ± 2.528
3.518ThrThr: 3.518 ± 1.575
3.518ThrVal: 3.518 ± 0.905
0.88ThrTrp: 0.88 ± 0.683
1.759ThrTyr: 1.759 ± 0.96
0.0ThrXaa: 0.0 ± 0.0
Val
5.277ValAla: 5.277 ± 2.12
0.88ValCys: 0.88 ± 0.683
0.88ValAsp: 0.88 ± 0.624
2.639ValGlu: 2.639 ± 1.062
0.88ValPhe: 0.88 ± 0.624
1.759ValGly: 1.759 ± 0.681
0.0ValHis: 0.0 ± 0.0
6.157ValIle: 6.157 ± 1.965
4.398ValLys: 4.398 ± 2.508
6.157ValLeu: 6.157 ± 1.832
1.759ValMet: 1.759 ± 0.708
1.759ValAsn: 1.759 ± 2.039
3.518ValPro: 3.518 ± 1.298
2.639ValGln: 2.639 ± 2.154
4.398ValArg: 4.398 ± 2.133
1.759ValSer: 1.759 ± 0.799
0.88ValThr: 0.88 ± 0.683
1.759ValVal: 1.759 ± 1.253
0.0ValTrp: 0.0 ± 0.0
1.759ValTyr: 1.759 ± 0.799
0.0ValXaa: 0.0 ± 0.0
Trp
0.88TrpAla: 0.88 ± 0.624
0.0TrpCys: 0.0 ± 0.0
0.88TrpAsp: 0.88 ± 1.013
0.88TrpGlu: 0.88 ± 0.683
0.0TrpPhe: 0.0 ± 0.0
0.88TrpGly: 0.88 ± 0.624
0.88TrpHis: 0.88 ± 0.683
1.759TrpIle: 1.759 ± 1.184
1.759TrpLys: 1.759 ± 0.681
0.88TrpLeu: 0.88 ± 0.624
0.0TrpMet: 0.0 ± 0.0
1.759TrpAsn: 1.759 ± 1.315
0.0TrpPro: 0.0 ± 0.0
1.759TrpGln: 1.759 ± 0.681
0.88TrpArg: 0.88 ± 0.928
3.518TrpSer: 3.518 ± 1.165
2.639TrpThr: 2.639 ± 1.4
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
1.759TyrAsp: 1.759 ± 0.905
2.639TyrGlu: 2.639 ± 1.534
0.88TyrPhe: 0.88 ± 0.683
0.88TyrGly: 0.88 ± 0.624
0.0TyrHis: 0.0 ± 0.0
4.398TyrIle: 4.398 ± 2.3
5.277TyrLys: 5.277 ± 1.647
3.518TyrLeu: 3.518 ± 0.892
2.639TyrMet: 2.639 ± 1.494
4.398TyrAsn: 4.398 ± 2.3
0.88TyrPro: 0.88 ± 0.624
1.759TyrGln: 1.759 ± 0.681
3.518TyrArg: 3.518 ± 1.351
2.639TyrSer: 2.639 ± 1.81
0.88TyrThr: 0.88 ± 0.928
2.639TyrVal: 2.639 ± 1.213
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1138 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski