Amino acid dipepetide frequency for Sweet potato leaf curl virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.372AlaAla: 5.372 ± 2.867
0.0AlaCys: 0.0 ± 0.0
2.686AlaAsp: 2.686 ± 2.27
4.476AlaGlu: 4.476 ± 1.892
0.895AlaPhe: 0.895 ± 0.731
1.791AlaGly: 1.791 ± 0.905
0.0AlaHis: 0.0 ± 0.0
2.686AlaIle: 2.686 ± 0.77
5.372AlaLys: 5.372 ± 1.548
6.267AlaLeu: 6.267 ± 1.082
0.0AlaMet: 0.0 ± 0.0
4.476AlaAsn: 4.476 ± 0.864
1.791AlaPro: 1.791 ± 0.905
2.686AlaGln: 2.686 ± 1.275
5.372AlaArg: 5.372 ± 2.102
1.791AlaSer: 1.791 ± 1.35
2.686AlaThr: 2.686 ± 1.286
1.791AlaVal: 1.791 ± 0.641
0.895AlaTrp: 0.895 ± 0.632
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.791CysCys: 1.791 ± 1.712
0.895CysAsp: 0.895 ± 0.632
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.686CysGly: 2.686 ± 1.434
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.686CysLys: 2.686 ± 0.788
0.895CysLeu: 0.895 ± 0.632
0.895CysMet: 0.895 ± 0.856
1.791CysAsn: 1.791 ± 0.905
5.372CysPro: 5.372 ± 3.458
0.0CysGln: 0.0 ± 0.0
0.895CysArg: 0.895 ± 0.675
5.372CysSer: 5.372 ± 1.653
1.791CysThr: 1.791 ± 0.905
1.791CysVal: 1.791 ± 1.35
0.895CysTrp: 0.895 ± 1.061
1.791CysTyr: 1.791 ± 0.951
0.0CysXaa: 0.0 ± 0.0
Asp
0.895AspAla: 0.895 ± 0.632
2.686AspCys: 2.686 ± 0.915
3.581AspAsp: 3.581 ± 0.726
1.791AspGlu: 1.791 ± 1.189
0.895AspPhe: 0.895 ± 0.675
3.581AspGly: 3.581 ± 1.648
0.895AspHis: 0.895 ± 0.675
0.895AspIle: 0.895 ± 0.632
1.791AspLys: 1.791 ± 1.264
5.372AspLeu: 5.372 ± 1.327
0.895AspMet: 0.895 ± 0.856
2.686AspAsn: 2.686 ± 1.468
2.686AspPro: 2.686 ± 1.202
0.895AspGln: 0.895 ± 0.675
5.372AspArg: 5.372 ± 1.56
4.476AspSer: 4.476 ± 1.236
2.686AspThr: 2.686 ± 1.069
4.476AspVal: 4.476 ± 1.458
2.686AspTrp: 2.686 ± 1.286
1.791AspTyr: 1.791 ± 0.951
0.0AspXaa: 0.0 ± 0.0
Glu
5.372GluAla: 5.372 ± 1.487
0.895GluCys: 0.895 ± 0.856
1.791GluAsp: 1.791 ± 1.264
5.372GluGlu: 5.372 ± 1.298
3.581GluPhe: 3.581 ± 0.98
5.372GluGly: 5.372 ± 2.374
0.895GluHis: 0.895 ± 0.731
0.895GluIle: 0.895 ± 0.856
2.686GluLys: 2.686 ± 1.329
4.476GluLeu: 4.476 ± 2.556
0.0GluMet: 0.0 ± 0.0
3.581GluAsn: 3.581 ± 1.207
3.581GluPro: 3.581 ± 0.937
1.791GluGln: 1.791 ± 0.641
1.791GluArg: 1.791 ± 1.796
3.581GluSer: 3.581 ± 1.611
2.686GluThr: 2.686 ± 1.202
2.686GluVal: 2.686 ± 1.275
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.895PheCys: 0.895 ± 0.632
2.686PheAsp: 2.686 ± 0.77
2.686PheGlu: 2.686 ± 0.778
1.791PhePhe: 1.791 ± 0.641
0.895PheGly: 0.895 ± 0.731
2.686PheHis: 2.686 ± 0.77
1.791PheIle: 1.791 ± 0.833
4.476PheLys: 4.476 ± 1.14
2.686PheLeu: 2.686 ± 1.689
0.895PheMet: 0.895 ± 0.632
1.791PheAsn: 1.791 ± 0.905
0.0PhePro: 0.0 ± 0.0
3.581PheGln: 3.581 ± 1.293
3.581PheArg: 3.581 ± 1.712
2.686PheSer: 2.686 ± 1.079
3.581PheThr: 3.581 ± 1.818
2.686PheVal: 2.686 ± 0.77
0.895PheTrp: 0.895 ± 0.632
0.895PheTyr: 0.895 ± 0.675
0.0PheXaa: 0.0 ± 0.0
Gly
4.476GlyAla: 4.476 ± 2.377
2.686GlyCys: 2.686 ± 1.556
1.791GlyAsp: 1.791 ± 0.641
6.267GlyGlu: 6.267 ± 2.12
5.372GlyPhe: 5.372 ± 3.038
3.581GlyGly: 3.581 ± 1.281
0.895GlyHis: 0.895 ± 0.632
5.372GlyIle: 5.372 ± 1.424
6.267GlyLys: 6.267 ± 1.354
3.581GlyLeu: 3.581 ± 1.498
0.895GlyMet: 0.895 ± 0.809
1.791GlyAsn: 1.791 ± 1.296
3.581GlyPro: 3.581 ± 1.281
2.686GlyGln: 2.686 ± 1.286
5.372GlyArg: 5.372 ± 2.035
2.686GlySer: 2.686 ± 1.286
2.686GlyThr: 2.686 ± 1.202
1.791GlyVal: 1.791 ± 1.296
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.686HisAla: 2.686 ± 1.095
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.791HisGlu: 1.791 ± 0.905
1.791HisPhe: 1.791 ± 1.264
0.895HisGly: 0.895 ± 0.731
0.0HisHis: 0.0 ± 0.0
1.791HisIle: 1.791 ± 1.264
2.686HisLys: 2.686 ± 1.468
1.791HisLeu: 1.791 ± 1.264
0.0HisMet: 0.0 ± 0.0
2.686HisAsn: 2.686 ± 1.079
3.581HisPro: 3.581 ± 1.013
0.0HisGln: 0.0 ± 0.0
2.686HisArg: 2.686 ± 1.479
1.791HisSer: 1.791 ± 0.905
1.791HisThr: 1.791 ± 0.951
2.686HisVal: 2.686 ± 0.788
0.895HisTrp: 0.895 ± 0.856
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.686IleAla: 2.686 ± 1.01
0.895IleCys: 0.895 ± 0.898
3.581IleAsp: 3.581 ± 1.546
0.895IleGlu: 0.895 ± 0.632
4.476IlePhe: 4.476 ± 1.732
1.791IleGly: 1.791 ± 0.905
1.791IleHis: 1.791 ± 0.905
2.686IleIle: 2.686 ± 1.079
0.895IleLys: 0.895 ± 0.632
3.581IleLeu: 3.581 ± 2.759
0.895IleMet: 0.895 ± 0.898
0.0IleAsn: 0.0 ± 0.0
4.476IlePro: 4.476 ± 1.449
4.476IleGln: 4.476 ± 2.229
6.267IleArg: 6.267 ± 1.329
3.581IleSer: 3.581 ± 1.866
4.476IleThr: 4.476 ± 1.449
2.686IleVal: 2.686 ± 0.788
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.895LysCys: 0.895 ± 0.731
2.686LysAsp: 2.686 ± 1.079
7.162LysGlu: 7.162 ± 1.795
3.581LysPhe: 3.581 ± 1.131
3.581LysGly: 3.581 ± 1.207
0.895LysHis: 0.895 ± 0.632
1.791LysIle: 1.791 ± 1.013
4.476LysLys: 4.476 ± 1.054
2.686LysLeu: 2.686 ± 1.329
0.895LysMet: 0.895 ± 0.675
1.791LysAsn: 1.791 ± 1.264
1.791LysPro: 1.791 ± 1.264
0.0LysGln: 0.0 ± 0.0
7.162LysArg: 7.162 ± 2.538
3.581LysSer: 3.581 ± 1.066
1.791LysThr: 1.791 ± 0.922
6.267LysVal: 6.267 ± 1.626
0.895LysTrp: 0.895 ± 0.898
5.372LysTyr: 5.372 ± 2.185
0.0LysXaa: 0.0 ± 0.0
Leu
1.791LeuAla: 1.791 ± 0.905
3.581LeuCys: 3.581 ± 1.843
4.476LeuAsp: 4.476 ± 2.073
3.581LeuGlu: 3.581 ± 2.242
1.791LeuPhe: 1.791 ± 0.922
3.581LeuGly: 3.581 ± 0.813
4.476LeuHis: 4.476 ± 1.833
2.686LeuIle: 2.686 ± 1.455
6.267LeuLys: 6.267 ± 1.229
3.581LeuLeu: 3.581 ± 2.164
1.791LeuMet: 1.791 ± 1.198
3.581LeuAsn: 3.581 ± 1.429
4.476LeuPro: 4.476 ± 1.54
4.476LeuGln: 4.476 ± 1.753
3.581LeuArg: 3.581 ± 1.501
5.372LeuSer: 5.372 ± 1.908
5.372LeuThr: 5.372 ± 2.655
5.372LeuVal: 5.372 ± 1.774
0.895LeuTrp: 0.895 ± 0.632
3.581LeuTyr: 3.581 ± 1.501
0.0LeuXaa: 0.0 ± 0.0
Met
1.791MetAla: 1.791 ± 0.922
0.895MetCys: 0.895 ± 1.061
4.476MetAsp: 4.476 ± 1.696
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
2.686MetGly: 2.686 ± 1.01
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.895MetLys: 0.895 ± 0.675
2.686MetLeu: 2.686 ± 1.696
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.895MetGln: 0.895 ± 0.675
2.686MetArg: 2.686 ± 1.791
2.686MetSer: 2.686 ± 1.511
0.895MetThr: 0.895 ± 0.675
0.0MetVal: 0.0 ± 0.0
0.895MetTrp: 0.895 ± 0.856
1.791MetTyr: 1.791 ± 1.013
0.0MetXaa: 0.0 ± 0.0
Asn
5.372AsnAla: 5.372 ± 1.458
1.791AsnCys: 1.791 ± 0.922
0.895AsnAsp: 0.895 ± 0.632
1.791AsnGlu: 1.791 ± 0.951
1.791AsnPhe: 1.791 ± 1.35
0.895AsnGly: 0.895 ± 0.898
4.476AsnHis: 4.476 ± 1.791
2.686AsnIle: 2.686 ± 0.77
1.791AsnLys: 1.791 ± 0.641
5.372AsnLeu: 5.372 ± 1.751
0.895AsnMet: 0.895 ± 0.642
2.686AsnAsn: 2.686 ± 1.095
5.372AsnPro: 5.372 ± 0.999
0.895AsnGln: 0.895 ± 0.675
0.0AsnArg: 0.0 ± 0.0
3.581AsnSer: 3.581 ± 1.907
0.0AsnThr: 0.0 ± 0.0
3.581AsnVal: 3.581 ± 1.066
1.791AsnTrp: 1.791 ± 0.833
3.581AsnTyr: 3.581 ± 0.98
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.895ProCys: 0.895 ± 0.675
3.581ProAsp: 3.581 ± 1.843
2.686ProGlu: 2.686 ± 1.286
2.686ProPhe: 2.686 ± 1.277
3.581ProGly: 3.581 ± 1.787
3.581ProHis: 3.581 ± 1.066
4.476ProIle: 4.476 ± 2.06
3.581ProLys: 3.581 ± 1.038
3.581ProLeu: 3.581 ± 1.857
2.686ProMet: 2.686 ± 1.531
4.476ProAsn: 4.476 ± 1.489
3.581ProPro: 3.581 ± 1.848
4.476ProGln: 4.476 ± 2.124
3.581ProArg: 3.581 ± 1.201
4.476ProSer: 4.476 ± 1.239
6.267ProThr: 6.267 ± 1.746
3.581ProVal: 3.581 ± 1.779
0.0ProTrp: 0.0 ± 0.0
2.686ProTyr: 2.686 ± 2.025
0.0ProXaa: 0.0 ± 0.0
Gln
0.895GlnAla: 0.895 ± 0.675
0.0GlnCys: 0.0 ± 0.0
2.686GlnAsp: 2.686 ± 1.556
2.686GlnGlu: 2.686 ± 1.286
1.791GlnPhe: 1.791 ± 0.905
4.476GlnGly: 4.476 ± 1.183
0.895GlnHis: 0.895 ± 0.731
3.581GlnIle: 3.581 ± 1.16
0.0GlnLys: 0.0 ± 0.0
4.476GlnLeu: 4.476 ± 1.236
0.895GlnMet: 0.895 ± 0.898
0.895GlnAsn: 0.895 ± 0.856
1.791GlnPro: 1.791 ± 1.206
1.791GlnGln: 1.791 ± 0.833
1.791GlnArg: 1.791 ± 1.296
4.476GlnSer: 4.476 ± 1.892
3.581GlnThr: 3.581 ± 0.98
2.686GlnVal: 2.686 ± 1.154
0.0GlnTrp: 0.0 ± 0.0
2.686GlnTyr: 2.686 ± 1.329
0.0GlnXaa: 0.0 ± 0.0
Arg
2.686ArgAla: 2.686 ± 1.867
2.686ArgCys: 2.686 ± 0.778
3.581ArgAsp: 3.581 ± 2.017
3.581ArgGlu: 3.581 ± 1.201
2.686ArgPhe: 2.686 ± 1.079
5.372ArgGly: 5.372 ± 1.683
0.0ArgHis: 0.0 ± 0.0
9.848ArgIle: 9.848 ± 1.964
3.581ArgLys: 3.581 ± 1.902
5.372ArgLeu: 5.372 ± 3.192
3.581ArgMet: 3.581 ± 2.7
0.0ArgAsn: 0.0 ± 0.0
5.372ArgPro: 5.372 ± 1.163
2.686ArgGln: 2.686 ± 1.316
6.267ArgArg: 6.267 ± 2.165
4.476ArgSer: 4.476 ± 1.448
5.372ArgThr: 5.372 ± 2.922
5.372ArgVal: 5.372 ± 2.371
0.0ArgTrp: 0.0 ± 0.0
1.791ArgTyr: 1.791 ± 1.189
0.0ArgXaa: 0.0 ± 0.0
Ser
6.267SerAla: 6.267 ± 1.027
0.895SerCys: 0.895 ± 0.731
4.476SerAsp: 4.476 ± 1.475
0.895SerGlu: 0.895 ± 0.856
1.791SerPhe: 1.791 ± 1.264
2.686SerGly: 2.686 ± 0.788
4.476SerHis: 4.476 ± 1.512
1.791SerIle: 1.791 ± 0.922
3.581SerLys: 3.581 ± 1.696
3.581SerLeu: 3.581 ± 1.81
3.581SerMet: 3.581 ± 1.17
5.372SerAsn: 5.372 ± 2.136
8.057SerPro: 8.057 ± 2.563
0.895SerGln: 0.895 ± 0.731
6.267SerArg: 6.267 ± 2.93
13.429SerSer: 13.429 ± 4.779
3.581SerThr: 3.581 ± 2.398
3.581SerVal: 3.581 ± 1.505
2.686SerTrp: 2.686 ± 1.925
2.686SerTyr: 2.686 ± 0.778
0.0SerXaa: 0.0 ± 0.0
Thr
6.267ThrAla: 6.267 ± 1.303
0.895ThrCys: 0.895 ± 0.731
0.895ThrAsp: 0.895 ± 0.898
0.895ThrGlu: 0.895 ± 0.856
1.791ThrPhe: 1.791 ± 1.296
8.953ThrGly: 8.953 ± 3.283
1.791ThrHis: 1.791 ± 0.951
2.686ThrIle: 2.686 ± 1.689
0.895ThrLys: 0.895 ± 0.731
5.372ThrLeu: 5.372 ± 2.361
1.791ThrMet: 1.791 ± 1.013
3.581ThrAsn: 3.581 ± 1.066
2.686ThrPro: 2.686 ± 1.0
3.581ThrGln: 3.581 ± 1.225
5.372ThrArg: 5.372 ± 1.897
1.791ThrSer: 1.791 ± 2.121
4.476ThrThr: 4.476 ± 1.885
1.791ThrVal: 1.791 ± 0.641
0.895ThrTrp: 0.895 ± 0.632
2.686ThrTyr: 2.686 ± 1.154
0.0ThrXaa: 0.0 ± 0.0
Val
0.895ValAla: 0.895 ± 0.675
5.372ValCys: 5.372 ± 1.43
2.686ValAsp: 2.686 ± 1.277
0.0ValGlu: 0.0 ± 0.0
1.791ValPhe: 1.791 ± 1.013
0.895ValGly: 0.895 ± 0.675
0.895ValHis: 0.895 ± 0.898
2.686ValIle: 2.686 ± 1.277
4.476ValLys: 4.476 ± 0.811
2.686ValLeu: 2.686 ± 0.77
0.895ValMet: 0.895 ± 0.632
4.476ValAsn: 4.476 ± 2.704
5.372ValPro: 5.372 ± 2.422
3.581ValGln: 3.581 ± 1.648
3.581ValArg: 3.581 ± 2.017
5.372ValSer: 5.372 ± 1.493
2.686ValThr: 2.686 ± 2.025
0.0ValVal: 0.0 ± 0.0
3.581ValTrp: 3.581 ± 0.937
3.581ValTyr: 3.581 ± 1.281
0.0ValXaa: 0.0 ± 0.0
Trp
2.686TrpAla: 2.686 ± 1.896
1.791TrpCys: 1.791 ± 1.206
0.895TrpAsp: 0.895 ± 0.856
0.895TrpGlu: 0.895 ± 0.856
0.0TrpPhe: 0.0 ± 0.0
1.791TrpGly: 1.791 ± 0.922
0.0TrpHis: 0.0 ± 0.0
0.895TrpIle: 0.895 ± 0.898
0.895TrpLys: 0.895 ± 0.731
1.791TrpLeu: 1.791 ± 0.641
0.895TrpMet: 0.895 ± 0.675
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.895TrpGln: 0.895 ± 0.632
0.895TrpArg: 0.895 ± 0.898
0.895TrpSer: 0.895 ± 0.856
1.791TrpThr: 1.791 ± 0.905
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.791TrpTyr: 1.791 ± 0.833
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.895TyrAla: 0.895 ± 0.856
0.0TyrCys: 0.0 ± 0.0
2.686TyrAsp: 2.686 ± 1.43
3.581TyrGlu: 3.581 ± 1.572
2.686TyrPhe: 2.686 ± 0.788
2.686TyrGly: 2.686 ± 0.778
0.895TyrHis: 0.895 ± 0.632
0.895TyrIle: 0.895 ± 0.632
0.0TyrLys: 0.0 ± 0.0
4.476TyrLeu: 4.476 ± 1.732
0.0TyrMet: 0.0 ± 0.777
3.581TyrAsn: 3.581 ± 1.779
0.895TyrPro: 0.895 ± 0.632
1.791TyrGln: 1.791 ± 0.951
1.791TyrArg: 1.791 ± 1.189
4.476TyrSer: 4.476 ± 1.236
0.895TyrThr: 0.895 ± 0.675
2.686TyrVal: 2.686 ± 0.77
0.895TyrTrp: 0.895 ± 0.675
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1118 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski