Amino acid dipepetide frequency for Abalone herpesvirus (isolate Abalone/Australia/Victoria/2009) (AbHV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.724AlaAla: 3.724 ± 0.285
1.14AlaCys: 1.14 ± 0.152
2.762AlaAsp: 2.762 ± 0.228
4.775AlaGlu: 4.775 ± 0.417
2.299AlaPhe: 2.299 ± 0.167
3.243AlaGly: 3.243 ± 0.283
1.158AlaHis: 1.158 ± 0.111
2.762AlaIle: 2.762 ± 0.256
3.778AlaLys: 3.778 ± 0.262
5.06AlaLeu: 5.06 ± 0.352
1.711AlaMet: 1.711 ± 0.178
2.299AlaAsn: 2.299 ± 0.186
2.726AlaPro: 2.726 ± 0.309
2.174AlaGln: 2.174 ± 0.188
3.671AlaArg: 3.671 ± 0.294
4.205AlaSer: 4.205 ± 0.269
2.904AlaThr: 2.904 ± 0.24
4.223AlaVal: 4.223 ± 0.252
0.499AlaTrp: 0.499 ± 0.085
1.889AlaTyr: 1.889 ± 0.178
0.0AlaXaa: 0.0 ± 0.0
Cys
1.212CysAla: 1.212 ± 0.135
0.374CysCys: 0.374 ± 0.091
1.229CysAsp: 1.229 ± 0.158
1.568CysGlu: 1.568 ± 0.155
0.641CysPhe: 0.641 ± 0.111
1.425CysGly: 1.425 ± 0.204
0.374CysHis: 0.374 ± 0.088
0.677CysIle: 0.677 ± 0.105
1.586CysLys: 1.586 ± 0.178
1.55CysLeu: 1.55 ± 0.204
0.677CysMet: 0.677 ± 0.127
0.784CysAsn: 0.784 ± 0.118
0.677CysPro: 0.677 ± 0.112
0.606CysGln: 0.606 ± 0.092
0.962CysArg: 0.962 ± 0.172
1.123CysSer: 1.123 ± 0.21
1.265CysThr: 1.265 ± 0.198
1.853CysVal: 1.853 ± 0.2
0.125CysTrp: 0.125 ± 0.045
0.659CysTyr: 0.659 ± 0.1
0.0CysXaa: 0.0 ± 0.0
Asp
2.94AspAla: 2.94 ± 0.242
1.033AspCys: 1.033 ± 0.139
4.829AspAsp: 4.829 ± 0.436
6.005AspGlu: 6.005 ± 0.413
3.065AspPhe: 3.065 ± 0.227
3.243AspGly: 3.243 ± 0.26
1.069AspHis: 1.069 ± 0.14
3.029AspIle: 3.029 ± 0.239
3.938AspLys: 3.938 ± 0.281
5.167AspLeu: 5.167 ± 0.299
1.889AspMet: 1.889 ± 0.183
2.21AspAsn: 2.21 ± 0.207
2.299AspPro: 2.299 ± 0.21
1.782AspGln: 1.782 ± 0.157
2.78AspArg: 2.78 ± 0.254
3.421AspSer: 3.421 ± 0.238
2.512AspThr: 2.512 ± 0.218
4.668AspVal: 4.668 ± 0.268
0.499AspTrp: 0.499 ± 0.09
2.904AspTyr: 2.904 ± 0.305
0.0AspXaa: 0.0 ± 0.0
Glu
4.704GluAla: 4.704 ± 0.397
1.051GluCys: 1.051 ± 0.137
5.613GluAsp: 5.613 ± 0.395
10.121GluGlu: 10.121 ± 0.696
3.35GluPhe: 3.35 ± 0.271
4.027GluGly: 4.027 ± 0.33
1.425GluHis: 1.425 ± 0.138
4.758GluIle: 4.758 ± 0.271
6.237GluLys: 6.237 ± 0.435
6.379GluLeu: 6.379 ± 0.284
2.174GluMet: 2.174 ± 0.205
4.134GluAsn: 4.134 ± 0.31
2.958GluPro: 2.958 ± 0.361
2.459GluGln: 2.459 ± 0.294
4.562GluArg: 4.562 ± 0.412
4.383GluSer: 4.383 ± 0.29
4.312GluThr: 4.312 ± 0.274
5.256GluVal: 5.256 ± 0.325
0.641GluTrp: 0.641 ± 0.103
1.711GluTyr: 1.711 ± 0.179
0.0GluXaa: 0.0 ± 0.0
Phe
2.37PheAla: 2.37 ± 0.248
1.158PheCys: 1.158 ± 0.151
2.744PheAsp: 2.744 ± 0.251
2.548PheGlu: 2.548 ± 0.209
2.263PhePhe: 2.263 ± 0.215
1.924PheGly: 1.924 ± 0.182
0.909PheHis: 0.909 ± 0.128
2.887PheIle: 2.887 ± 0.267
2.708PheLys: 2.708 ± 0.23
3.76PheLeu: 3.76 ± 0.28
1.354PheMet: 1.354 ± 0.16
2.21PheAsn: 2.21 ± 0.207
1.586PhePro: 1.586 ± 0.205
1.176PheGln: 1.176 ± 0.125
1.835PheArg: 1.835 ± 0.181
2.922PheSer: 2.922 ± 0.224
2.922PheThr: 2.922 ± 0.251
3.457PheVal: 3.457 ± 0.271
0.481PheTrp: 0.481 ± 0.104
1.996PheTyr: 1.996 ± 0.175
0.0PheXaa: 0.0 ± 0.0
Gly
2.512GlyAla: 2.512 ± 0.181
1.033GlyCys: 1.033 ± 0.141
2.958GlyAsp: 2.958 ± 0.255
4.651GlyGlu: 4.651 ± 0.303
2.334GlyPhe: 2.334 ± 0.23
3.51GlyGly: 3.51 ± 0.313
0.695GlyHis: 0.695 ± 0.134
2.619GlyIle: 2.619 ± 0.216
3.974GlyLys: 3.974 ± 0.246
3.92GlyLeu: 3.92 ± 0.286
1.604GlyMet: 1.604 ± 0.154
1.96GlyAsn: 1.96 ± 0.187
1.319GlyPro: 1.319 ± 0.139
1.39GlyGln: 1.39 ± 0.155
2.53GlyArg: 2.53 ± 0.252
3.492GlySer: 3.492 ± 0.258
3.332GlyThr: 3.332 ± 0.248
4.187GlyVal: 4.187 ± 0.313
0.356GlyTrp: 0.356 ± 0.093
1.568GlyTyr: 1.568 ± 0.174
0.0GlyXaa: 0.0 ± 0.0
His
1.229HisAla: 1.229 ± 0.143
0.445HisCys: 0.445 ± 0.092
1.176HisAsp: 1.176 ± 0.151
1.408HisGlu: 1.408 ± 0.161
0.909HisPhe: 0.909 ± 0.116
1.301HisGly: 1.301 ± 0.155
0.535HisHis: 0.535 ± 0.1
1.069HisIle: 1.069 ± 0.119
1.176HisLys: 1.176 ± 0.158
1.889HisLeu: 1.889 ± 0.164
0.445HisMet: 0.445 ± 0.083
0.98HisAsn: 0.98 ± 0.145
1.105HisPro: 1.105 ± 0.148
0.57HisGln: 0.57 ± 0.099
1.212HisArg: 1.212 ± 0.154
1.354HisSer: 1.354 ± 0.194
1.105HisThr: 1.105 ± 0.132
1.336HisVal: 1.336 ± 0.164
0.089HisTrp: 0.089 ± 0.044
0.606HisTyr: 0.606 ± 0.09
0.0HisXaa: 0.0 ± 0.0
Ile
2.869IleAla: 2.869 ± 0.27
1.016IleCys: 1.016 ± 0.121
3.956IleAsp: 3.956 ± 0.222
4.187IleGlu: 4.187 ± 0.309
2.762IlePhe: 2.762 ± 0.23
2.655IleGly: 2.655 ± 0.186
1.105IleHis: 1.105 ± 0.144
3.19IleIle: 3.19 ± 0.244
4.544IleLys: 4.544 ± 0.352
4.152IleLeu: 4.152 ± 0.243
1.853IleMet: 1.853 ± 0.19
3.884IleAsn: 3.884 ± 0.24
3.154IlePro: 3.154 ± 0.249
1.568IleGln: 1.568 ± 0.213
2.245IleArg: 2.245 ± 0.182
4.134IleSer: 4.134 ± 0.296
3.279IleThr: 3.279 ± 0.227
3.76IleVal: 3.76 ± 0.22
0.214IleTrp: 0.214 ± 0.061
2.227IleTyr: 2.227 ± 0.26
0.0IleXaa: 0.0 ± 0.0
Lys
4.08LysAla: 4.08 ± 0.322
1.194LysCys: 1.194 ± 0.154
3.849LysAsp: 3.849 ± 0.274
6.361LysGlu: 6.361 ± 0.498
3.029LysPhe: 3.029 ± 0.2
2.94LysGly: 2.94 ± 0.192
1.319LysHis: 1.319 ± 0.138
5.524LysIle: 5.524 ± 0.279
7.092LysLys: 7.092 ± 0.51
6.343LysLeu: 6.343 ± 0.393
2.459LysMet: 2.459 ± 0.207
4.348LysAsn: 4.348 ± 0.295
3.546LysPro: 3.546 ± 0.3
2.726LysGln: 2.726 ± 0.256
5.595LysArg: 5.595 ± 0.358
4.811LysSer: 4.811 ± 0.256
4.383LysThr: 4.383 ± 0.244
4.864LysVal: 4.864 ± 0.272
0.428LysTrp: 0.428 ± 0.075
1.693LysTyr: 1.693 ± 0.148
0.0LysXaa: 0.0 ± 0.0
Leu
4.847LeuAla: 4.847 ± 0.295
1.711LeuCys: 1.711 ± 0.15
4.134LeuAsp: 4.134 ± 0.268
5.203LeuGlu: 5.203 ± 0.367
3.225LeuPhe: 3.225 ± 0.251
3.92LeuGly: 3.92 ± 0.249
1.835LeuHis: 1.835 ± 0.22
5.47LeuIle: 5.47 ± 0.397
6.237LeuLys: 6.237 ± 0.325
7.038LeuLeu: 7.038 ± 0.462
2.459LeuMet: 2.459 ± 0.24
3.76LeuAsn: 3.76 ± 0.231
4.401LeuPro: 4.401 ± 0.329
2.887LeuGln: 2.887 ± 0.257
4.312LeuArg: 4.312 ± 0.31
6.522LeuSer: 6.522 ± 0.393
5.72LeuThr: 5.72 ± 0.293
4.989LeuVal: 4.989 ± 0.286
0.606LeuTrp: 0.606 ± 0.108
3.421LeuTyr: 3.421 ± 0.28
0.0LeuXaa: 0.0 ± 0.0
Met
1.675MetAla: 1.675 ± 0.165
0.481MetCys: 0.481 ± 0.098
1.621MetAsp: 1.621 ± 0.165
2.245MetGlu: 2.245 ± 0.224
1.087MetPhe: 1.087 ± 0.137
1.408MetGly: 1.408 ± 0.162
0.499MetHis: 0.499 ± 0.1
2.049MetIle: 2.049 ± 0.18
2.851MetLys: 2.851 ± 0.255
1.96MetLeu: 1.96 ± 0.204
1.194MetMet: 1.194 ± 0.156
1.782MetAsn: 1.782 ± 0.159
1.354MetPro: 1.354 ± 0.149
1.016MetGln: 1.016 ± 0.143
1.96MetArg: 1.96 ± 0.177
2.78MetSer: 2.78 ± 0.238
1.871MetThr: 1.871 ± 0.189
1.639MetVal: 1.639 ± 0.168
0.196MetTrp: 0.196 ± 0.054
0.998MetTyr: 0.998 ± 0.14
0.0MetXaa: 0.0 ± 0.0
Asn
2.851AsnAla: 2.851 ± 0.235
1.051AsnCys: 1.051 ± 0.137
2.744AsnAsp: 2.744 ± 0.256
3.599AsnGlu: 3.599 ± 0.266
2.691AsnPhe: 2.691 ± 0.204
2.584AsnGly: 2.584 ± 0.184
1.301AsnHis: 1.301 ± 0.156
2.655AsnIle: 2.655 ± 0.236
4.098AsnLys: 4.098 ± 0.288
4.419AsnLeu: 4.419 ± 0.244
1.55AsnMet: 1.55 ± 0.202
2.423AsnAsn: 2.423 ± 0.221
2.334AsnPro: 2.334 ± 0.2
1.889AsnGln: 1.889 ± 0.152
2.566AsnArg: 2.566 ± 0.228
3.243AsnSer: 3.243 ± 0.231
2.744AsnThr: 2.744 ± 0.227
3.011AsnVal: 3.011 ± 0.243
0.499AsnTrp: 0.499 ± 0.079
1.96AsnTyr: 1.96 ± 0.149
0.0AsnXaa: 0.0 ± 0.0
Pro
2.637ProAla: 2.637 ± 0.317
0.855ProCys: 0.855 ± 0.129
2.512ProAsp: 2.512 ± 0.208
3.279ProGlu: 3.279 ± 0.273
1.853ProPhe: 1.853 ± 0.197
2.067ProGly: 2.067 ± 0.174
0.873ProHis: 0.873 ± 0.111
2.477ProIle: 2.477 ± 0.192
3.207ProLys: 3.207 ± 0.298
3.386ProLeu: 3.386 ± 0.291
1.016ProMet: 1.016 ± 0.146
1.818ProAsn: 1.818 ± 0.146
3.528ProPro: 3.528 ± 0.737
1.479ProGln: 1.479 ± 0.203
2.156ProArg: 2.156 ± 0.236
3.778ProSer: 3.778 ± 0.311
3.083ProThr: 3.083 ± 0.235
3.884ProVal: 3.884 ± 0.322
0.285ProTrp: 0.285 ± 0.078
1.55ProTyr: 1.55 ± 0.132
0.0ProXaa: 0.0 ± 0.0
Gln
2.031GlnAla: 2.031 ± 0.175
0.535GlnCys: 0.535 ± 0.099
2.103GlnAsp: 2.103 ± 0.154
2.512GlnGlu: 2.512 ± 0.208
1.176GlnPhe: 1.176 ± 0.131
1.176GlnGly: 1.176 ± 0.131
0.944GlnHis: 0.944 ± 0.121
1.853GlnIle: 1.853 ± 0.16
2.584GlnLys: 2.584 ± 0.194
3.047GlnLeu: 3.047 ± 0.214
0.927GlnMet: 0.927 ± 0.129
1.782GlnAsn: 1.782 ± 0.144
1.229GlnPro: 1.229 ± 0.227
1.657GlnGln: 1.657 ± 0.314
2.192GlnArg: 2.192 ± 0.289
1.711GlnSer: 1.711 ± 0.22
2.53GlnThr: 2.53 ± 0.204
1.657GlnVal: 1.657 ± 0.164
0.303GlnTrp: 0.303 ± 0.066
1.087GlnTyr: 1.087 ± 0.136
0.0GlnXaa: 0.0 ± 0.0
Arg
3.778ArgAla: 3.778 ± 0.325
1.194ArgCys: 1.194 ± 0.163
2.94ArgAsp: 2.94 ± 0.215
5.167ArgGlu: 5.167 ± 0.517
2.245ArgPhe: 2.245 ± 0.162
2.673ArgGly: 2.673 ± 0.224
1.087ArgHis: 1.087 ± 0.151
2.352ArgIle: 2.352 ± 0.218
4.241ArgLys: 4.241 ± 0.345
4.49ArgLeu: 4.49 ± 0.347
1.942ArgMet: 1.942 ± 0.182
2.53ArgAsn: 2.53 ± 0.233
1.853ArgPro: 1.853 ± 0.208
1.782ArgGln: 1.782 ± 0.182
3.76ArgArg: 3.76 ± 0.39
3.279ArgSer: 3.279 ± 0.28
2.245ArgThr: 2.245 ± 0.237
4.098ArgVal: 4.098 ± 0.248
0.588ArgTrp: 0.588 ± 0.094
1.746ArgTyr: 1.746 ± 0.19
0.0ArgXaa: 0.0 ± 0.0
Ser
3.991SerAla: 3.991 ± 0.263
1.515SerCys: 1.515 ± 0.236
3.671SerAsp: 3.671 ± 0.218
5.114SerGlu: 5.114 ± 0.288
3.35SerPhe: 3.35 ± 0.267
3.492SerGly: 3.492 ± 0.281
1.461SerHis: 1.461 ± 0.176
3.118SerIle: 3.118 ± 0.276
5.221SerLys: 5.221 ± 0.351
5.934SerLeu: 5.934 ± 0.384
1.835SerMet: 1.835 ± 0.196
3.528SerAsn: 3.528 ± 0.251
2.94SerPro: 2.94 ± 0.222
2.441SerGln: 2.441 ± 0.176
3.475SerArg: 3.475 ± 0.222
6.254SerSer: 6.254 ± 0.392
4.187SerThr: 4.187 ± 0.289
4.579SerVal: 4.579 ± 0.283
0.837SerTrp: 0.837 ± 0.113
2.815SerTyr: 2.815 ± 0.239
0.0SerXaa: 0.0 ± 0.0
Thr
3.439ThrAla: 3.439 ± 0.295
1.087ThrCys: 1.087 ± 0.152
3.599ThrAsp: 3.599 ± 0.236
3.991ThrGlu: 3.991 ± 0.293
2.495ThrPhe: 2.495 ± 0.187
3.011ThrGly: 3.011 ± 0.253
1.443ThrHis: 1.443 ± 0.184
3.261ThrIle: 3.261 ± 0.224
3.974ThrLys: 3.974 ± 0.293
5.506ThrLeu: 5.506 ± 0.313
1.657ThrMet: 1.657 ± 0.154
2.904ThrAsn: 2.904 ± 0.259
3.884ThrPro: 3.884 ± 0.316
1.942ThrGln: 1.942 ± 0.186
2.406ThrArg: 2.406 ± 0.201
4.455ThrSer: 4.455 ± 0.306
4.223ThrThr: 4.223 ± 0.337
4.009ThrVal: 4.009 ± 0.307
0.481ThrTrp: 0.481 ± 0.099
1.818ThrTyr: 1.818 ± 0.184
0.0ThrXaa: 0.0 ± 0.0
Val
3.653ValAla: 3.653 ± 0.231
1.693ValCys: 1.693 ± 0.176
3.956ValAsp: 3.956 ± 0.264
4.455ValGlu: 4.455 ± 0.265
2.869ValPhe: 2.869 ± 0.208
2.958ValGly: 2.958 ± 0.205
1.069ValHis: 1.069 ± 0.117
4.472ValIle: 4.472 ± 0.356
5.773ValLys: 5.773 ± 0.328
6.041ValLeu: 6.041 ± 0.33
2.299ValMet: 2.299 ± 0.214
3.884ValAsn: 3.884 ± 0.252
3.403ValPro: 3.403 ± 0.251
2.495ValGln: 2.495 ± 0.179
3.546ValArg: 3.546 ± 0.229
4.704ValSer: 4.704 ± 0.272
4.312ValThr: 4.312 ± 0.268
5.256ValVal: 5.256 ± 0.366
0.499ValTrp: 0.499 ± 0.096
2.37ValTyr: 2.37 ± 0.215
0.0ValXaa: 0.0 ± 0.0
Trp
0.267TrpAla: 0.267 ± 0.077
0.232TrpCys: 0.232 ± 0.06
0.535TrpAsp: 0.535 ± 0.103
0.588TrpGlu: 0.588 ± 0.096
0.392TrpPhe: 0.392 ± 0.09
0.445TrpGly: 0.445 ± 0.088
0.16TrpHis: 0.16 ± 0.053
0.57TrpIle: 0.57 ± 0.087
0.552TrpLys: 0.552 ± 0.099
0.588TrpLeu: 0.588 ± 0.113
0.41TrpMet: 0.41 ± 0.076
0.392TrpAsn: 0.392 ± 0.107
0.339TrpPro: 0.339 ± 0.084
0.16TrpGln: 0.16 ± 0.051
0.499TrpArg: 0.499 ± 0.098
0.695TrpSer: 0.695 ± 0.113
0.41TrpThr: 0.41 ± 0.08
0.321TrpVal: 0.321 ± 0.075
0.107TrpTrp: 0.107 ± 0.042
0.321TrpTyr: 0.321 ± 0.078
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.192TyrAla: 2.192 ± 0.186
0.57TyrCys: 0.57 ± 0.114
2.352TyrAsp: 2.352 ± 0.222
2.477TyrGlu: 2.477 ± 0.234
1.176TyrPhe: 1.176 ± 0.148
1.942TyrGly: 1.942 ± 0.156
0.677TyrHis: 0.677 ± 0.11
1.96TyrIle: 1.96 ± 0.183
2.815TyrLys: 2.815 ± 0.241
2.067TyrLeu: 2.067 ± 0.212
1.194TyrMet: 1.194 ± 0.149
2.619TyrAsn: 2.619 ± 0.234
1.087TyrPro: 1.087 ± 0.138
0.837TyrGln: 0.837 ± 0.114
1.728TyrArg: 1.728 ± 0.18
2.495TyrSer: 2.495 ± 0.193
2.245TyrThr: 2.245 ± 0.21
2.655TyrVal: 2.655 ± 0.203
0.249TyrTrp: 0.249 ± 0.066
0.962TyrTyr: 0.962 ± 0.125
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 112 proteins (56122 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski