Amino acid dipepetide frequency for Helicoverpa zea nudivirus 2 (HzNV-2)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.055AlaAla: 4.055 ± 0.859
0.762AlaCys: 0.762 ± 0.12
3.332AlaAsp: 3.332 ± 0.36
4.455AlaGlu: 4.455 ± 1.029
2.113AlaPhe: 2.113 ± 0.209
1.656AlaGly: 1.656 ± 0.195
1.009AlaHis: 1.009 ± 0.168
2.818AlaIle: 2.818 ± 0.22
5.197AlaLys: 5.197 ± 1.026
4.169AlaLeu: 4.169 ± 0.315
1.713AlaMet: 1.713 ± 0.221
4.017AlaAsn: 4.017 ± 0.36
2.189AlaPro: 2.189 ± 0.256
1.58AlaGln: 1.58 ± 0.196
2.304AlaArg: 2.304 ± 0.227
5.864AlaSer: 5.864 ± 0.498
4.093AlaThr: 4.093 ± 0.388
2.722AlaVal: 2.722 ± 0.267
0.267AlaTrp: 0.267 ± 0.067
1.809AlaTyr: 1.809 ± 0.228
0.0AlaXaa: 0.0 ± 0.0
Cys
0.666CysAla: 0.666 ± 0.107
0.4CysCys: 0.4 ± 0.109
1.199CysAsp: 1.199 ± 0.177
0.876CysGlu: 0.876 ± 0.128
0.628CysPhe: 0.628 ± 0.105
0.838CysGly: 0.838 ± 0.153
0.267CysHis: 0.267 ± 0.068
1.618CysIle: 1.618 ± 0.228
1.999CysLys: 1.999 ± 0.241
1.218CysLeu: 1.218 ± 0.151
0.819CysMet: 0.819 ± 0.132
1.923CysAsn: 1.923 ± 0.234
0.514CysPro: 0.514 ± 0.116
0.552CysGln: 0.552 ± 0.115
0.99CysArg: 0.99 ± 0.124
1.333CysSer: 1.333 ± 0.162
1.599CysThr: 1.599 ± 0.2
1.333CysVal: 1.333 ± 0.174
0.038CysTrp: 0.038 ± 0.029
0.781CysTyr: 0.781 ± 0.136
0.0CysXaa: 0.0 ± 0.0
Asp
5.407AspAla: 5.407 ± 0.394
1.371AspCys: 1.371 ± 0.177
6.454AspAsp: 6.454 ± 0.519
6.587AspGlu: 6.587 ± 0.787
2.361AspPhe: 2.361 ± 0.195
3.37AspGly: 3.37 ± 0.356
1.085AspHis: 1.085 ± 0.151
2.494AspIle: 2.494 ± 0.216
3.008AspLys: 3.008 ± 0.367
4.855AspLeu: 4.855 ± 0.342
1.257AspMet: 1.257 ± 0.182
2.627AspAsn: 2.627 ± 0.207
2.551AspPro: 2.551 ± 0.262
1.371AspGln: 1.371 ± 0.166
2.856AspArg: 2.856 ± 0.25
7.082AspSer: 7.082 ± 0.423
4.188AspThr: 4.188 ± 0.326
4.664AspVal: 4.664 ± 0.266
0.324AspTrp: 0.324 ± 0.07
3.103AspTyr: 3.103 ± 0.275
0.0AspXaa: 0.0 ± 0.0
Glu
4.398GluAla: 4.398 ± 0.85
2.037GluCys: 2.037 ± 0.262
4.893GluAsp: 4.893 ± 0.533
4.131GluGlu: 4.131 ± 0.406
2.837GluPhe: 2.837 ± 0.222
2.17GluGly: 2.17 ± 0.269
1.257GluHis: 1.257 ± 0.184
2.151GluIle: 2.151 ± 0.235
3.141GluLys: 3.141 ± 0.502
4.912GluLeu: 4.912 ± 0.366
1.599GluMet: 1.599 ± 0.222
3.103GluAsn: 3.103 ± 0.296
3.941GluPro: 3.941 ± 0.425
1.809GluGln: 1.809 ± 0.223
3.103GluArg: 3.103 ± 0.286
7.273GluSer: 7.273 ± 0.619
3.56GluThr: 3.56 ± 0.272
3.275GluVal: 3.275 ± 0.296
0.305GluTrp: 0.305 ± 0.067
3.103GluTyr: 3.103 ± 0.325
0.0GluXaa: 0.0 ± 0.0
Phe
1.923PheAla: 1.923 ± 0.253
0.457PheCys: 0.457 ± 0.103
3.179PheAsp: 3.179 ± 0.227
2.646PheGlu: 2.646 ± 0.276
0.857PhePhe: 0.857 ± 0.143
1.58PheGly: 1.58 ± 0.179
0.647PheHis: 0.647 ± 0.101
2.247PheIle: 2.247 ± 0.216
3.827PheLys: 3.827 ± 0.252
2.342PheLeu: 2.342 ± 0.24
1.257PheMet: 1.257 ± 0.162
3.484PheAsn: 3.484 ± 0.428
0.819PhePro: 0.819 ± 0.117
0.857PheGln: 0.857 ± 0.13
1.447PheArg: 1.447 ± 0.203
1.904PheSer: 1.904 ± 0.172
2.38PheThr: 2.38 ± 0.235
2.608PheVal: 2.608 ± 0.272
0.209PheTrp: 0.209 ± 0.077
1.542PheTyr: 1.542 ± 0.195
0.0PheXaa: 0.0 ± 0.0
Gly
2.113GlyAla: 2.113 ± 0.192
0.742GlyCys: 0.742 ± 0.123
2.761GlyAsp: 2.761 ± 0.21
1.675GlyGlu: 1.675 ± 0.148
1.752GlyPhe: 1.752 ± 0.222
3.865GlyGly: 3.865 ± 0.536
0.628GlyHis: 0.628 ± 0.158
2.247GlyIle: 2.247 ± 0.23
2.837GlyLys: 2.837 ± 0.359
2.57GlyLeu: 2.57 ± 0.31
1.028GlyMet: 1.028 ± 0.143
2.78GlyAsn: 2.78 ± 0.229
1.161GlyPro: 1.161 ± 0.154
0.895GlyGln: 0.895 ± 0.115
1.656GlyArg: 1.656 ± 0.191
5.369GlySer: 5.369 ± 0.465
3.122GlyThr: 3.122 ± 0.319
3.446GlyVal: 3.446 ± 0.315
0.209GlyTrp: 0.209 ± 0.057
1.599GlyTyr: 1.599 ± 0.188
0.0GlyXaa: 0.0 ± 0.0
His
1.333HisAla: 1.333 ± 0.183
0.305HisCys: 0.305 ± 0.08
1.047HisAsp: 1.047 ± 0.128
1.18HisGlu: 1.18 ± 0.205
1.085HisPhe: 1.085 ± 0.138
0.762HisGly: 0.762 ± 0.14
0.628HisHis: 0.628 ± 0.099
1.047HisIle: 1.047 ± 0.149
1.428HisLys: 1.428 ± 0.171
1.999HisLeu: 1.999 ± 0.196
0.476HisMet: 0.476 ± 0.095
1.218HisAsn: 1.218 ± 0.149
1.028HisPro: 1.028 ± 0.148
1.142HisGln: 1.142 ± 0.226
1.237HisArg: 1.237 ± 0.163
1.942HisSer: 1.942 ± 0.277
1.713HisThr: 1.713 ± 0.381
1.295HisVal: 1.295 ± 0.144
0.057HisTrp: 0.057 ± 0.032
0.971HisTyr: 0.971 ± 0.164
0.0HisXaa: 0.0 ± 0.0
Ile
3.141IleAla: 3.141 ± 0.319
0.781IleCys: 0.781 ± 0.135
4.664IleAsp: 4.664 ± 0.317
4.398IleGlu: 4.398 ± 0.302
1.333IlePhe: 1.333 ± 0.179
1.999IleGly: 1.999 ± 0.215
1.295IleHis: 1.295 ± 0.156
2.665IleIle: 2.665 ± 0.248
4.36IleLys: 4.36 ± 0.363
4.188IleLeu: 4.188 ± 0.337
1.599IleMet: 1.599 ± 0.164
4.303IleAsn: 4.303 ± 0.306
2.38IlePro: 2.38 ± 0.244
1.809IleGln: 1.809 ± 0.194
2.589IleArg: 2.589 ± 0.265
3.351IleSer: 3.351 ± 0.285
2.684IleThr: 2.684 ± 0.198
4.322IleVal: 4.322 ± 0.34
0.247IleTrp: 0.247 ± 0.064
1.333IleTyr: 1.333 ± 0.175
0.0IleXaa: 0.0 ± 0.0
Lys
4.474LysAla: 4.474 ± 1.33
1.752LysCys: 1.752 ± 0.268
3.77LysAsp: 3.77 ± 0.363
3.751LysGlu: 3.751 ± 0.406
2.113LysPhe: 2.113 ± 0.223
2.741LysGly: 2.741 ± 0.28
1.847LysHis: 1.847 ± 0.313
3.598LysIle: 3.598 ± 0.288
2.684LysLys: 2.684 ± 0.225
6.073LysLeu: 6.073 ± 0.394
1.675LysMet: 1.675 ± 0.191
3.503LysAsn: 3.503 ± 0.258
4.912LysPro: 4.912 ± 0.816
2.285LysGln: 2.285 ± 0.226
5.769LysArg: 5.769 ± 0.731
7.653LysSer: 7.653 ± 0.83
4.702LysThr: 4.702 ± 0.464
4.15LysVal: 4.15 ± 0.384
0.476LysTrp: 0.476 ± 0.106
2.208LysTyr: 2.208 ± 0.208
0.0LysXaa: 0.0 ± 0.0
Leu
4.074LeuAla: 4.074 ± 0.279
1.694LeuCys: 1.694 ± 0.205
5.083LeuAsp: 5.083 ± 0.39
4.893LeuGlu: 4.893 ± 0.305
3.103LeuPhe: 3.103 ± 0.372
2.932LeuGly: 2.932 ± 0.256
2.304LeuHis: 2.304 ± 0.231
3.96LeuIle: 3.96 ± 0.355
6.397LeuLys: 6.397 ± 0.525
6.663LeuLeu: 6.663 ± 0.482
2.665LeuMet: 2.665 ± 0.204
5.883LeuAsn: 5.883 ± 0.413
3.827LeuPro: 3.827 ± 0.336
2.494LeuGln: 2.494 ± 0.262
3.256LeuArg: 3.256 ± 0.289
4.95LeuSer: 4.95 ± 0.306
4.836LeuThr: 4.836 ± 0.322
4.931LeuVal: 4.931 ± 0.382
0.533LeuTrp: 0.533 ± 0.117
3.808LeuTyr: 3.808 ± 0.384
0.0LeuXaa: 0.0 ± 0.0
Met
1.599MetAla: 1.599 ± 0.216
0.704MetCys: 0.704 ± 0.154
2.113MetAsp: 2.113 ± 0.16
1.694MetGlu: 1.694 ± 0.231
1.314MetPhe: 1.314 ± 0.178
1.218MetGly: 1.218 ± 0.169
1.047MetHis: 1.047 ± 0.154
1.371MetIle: 1.371 ± 0.187
1.295MetLys: 1.295 ± 0.132
1.942MetLeu: 1.942 ± 0.224
0.857MetMet: 0.857 ± 0.098
1.561MetAsn: 1.561 ± 0.161
1.028MetPro: 1.028 ± 0.133
1.199MetGln: 1.199 ± 0.151
0.952MetArg: 0.952 ± 0.147
2.17MetSer: 2.17 ± 0.193
1.028MetThr: 1.028 ± 0.137
1.409MetVal: 1.409 ± 0.162
0.057MetTrp: 0.057 ± 0.033
1.542MetTyr: 1.542 ± 0.215
0.0MetXaa: 0.0 ± 0.0
Asn
4.055AsnAla: 4.055 ± 0.274
1.218AsnCys: 1.218 ± 0.194
3.693AsnAsp: 3.693 ± 0.303
3.236AsnGlu: 3.236 ± 0.393
2.494AsnPhe: 2.494 ± 0.215
3.579AsnGly: 3.579 ± 0.259
1.542AsnHis: 1.542 ± 0.277
3.77AsnIle: 3.77 ± 0.225
3.427AsnLys: 3.427 ± 0.307
5.597AsnLeu: 5.597 ± 0.38
1.199AsnMet: 1.199 ± 0.15
7.463AsnAsn: 7.463 ± 1.178
2.837AsnPro: 2.837 ± 0.292
2.665AsnGln: 2.665 ± 0.374
3.027AsnArg: 3.027 ± 0.27
6.587AsnSer: 6.587 ± 0.589
6.035AsnThr: 6.035 ± 0.68
4.95AsnVal: 4.95 ± 0.398
0.324AsnTrp: 0.324 ± 0.091
2.266AsnTyr: 2.266 ± 0.324
0.0AsnXaa: 0.0 ± 0.0
Pro
2.056ProAla: 2.056 ± 0.274
0.895ProCys: 0.895 ± 0.138
1.904ProAsp: 1.904 ± 0.225
3.256ProGlu: 3.256 ± 0.441
1.713ProPhe: 1.713 ± 0.233
1.18ProGly: 1.18 ± 0.173
0.685ProHis: 0.685 ± 0.115
2.741ProIle: 2.741 ± 0.243
4.436ProLys: 4.436 ± 0.655
3.16ProLeu: 3.16 ± 0.32
1.18ProMet: 1.18 ± 0.171
2.57ProAsn: 2.57 ± 0.291
3.046ProPro: 3.046 ± 0.55
1.257ProGln: 1.257 ± 0.173
1.371ProArg: 1.371 ± 0.194
4.246ProSer: 4.246 ± 0.385
5.426ProThr: 5.426 ± 0.826
2.608ProVal: 2.608 ± 0.252
0.286ProTrp: 0.286 ± 0.077
1.104ProTyr: 1.104 ± 0.18
0.0ProXaa: 0.0 ± 0.0
Gln
1.047GlnAla: 1.047 ± 0.139
0.895GlnCys: 0.895 ± 0.138
1.352GlnAsp: 1.352 ± 0.154
1.694GlnGlu: 1.694 ± 0.196
0.99GlnPhe: 0.99 ± 0.102
0.933GlnGly: 0.933 ± 0.148
1.104GlnHis: 1.104 ± 0.171
1.504GlnIle: 1.504 ± 0.122
1.732GlnLys: 1.732 ± 0.347
2.799GlnLeu: 2.799 ± 0.284
0.876GlnMet: 0.876 ± 0.131
1.923GlnAsn: 1.923 ± 0.262
2.037GlnPro: 2.037 ± 0.274
2.113GlnGln: 2.113 ± 0.324
1.371GlnArg: 1.371 ± 0.142
3.179GlnSer: 3.179 ± 0.341
2.57GlnThr: 2.57 ± 0.318
1.371GlnVal: 1.371 ± 0.158
0.19GlnTrp: 0.19 ± 0.073
1.466GlnTyr: 1.466 ± 0.177
0.0GlnXaa: 0.0 ± 0.0
Arg
2.113ArgAla: 2.113 ± 0.258
1.047ArgCys: 1.047 ± 0.143
2.57ArgAsp: 2.57 ± 0.265
2.018ArgGlu: 2.018 ± 0.232
1.885ArgPhe: 1.885 ± 0.215
1.847ArgGly: 1.847 ± 0.167
1.028ArgHis: 1.028 ± 0.138
3.294ArgIle: 3.294 ± 0.243
4.036ArgLys: 4.036 ± 0.688
4.721ArgLeu: 4.721 ± 0.339
1.276ArgMet: 1.276 ± 0.172
2.151ArgAsn: 2.151 ± 0.26
2.151ArgPro: 2.151 ± 0.216
1.257ArgGln: 1.257 ± 0.16
2.722ArgArg: 2.722 ± 0.269
3.712ArgSer: 3.712 ± 0.291
2.361ArgThr: 2.361 ± 0.276
3.846ArgVal: 3.846 ± 0.255
0.343ArgTrp: 0.343 ± 0.082
1.98ArgTyr: 1.98 ± 0.227
0.0ArgXaa: 0.0 ± 0.0
Ser
4.664SerAla: 4.664 ± 0.509
1.523SerCys: 1.523 ± 0.14
5.216SerAsp: 5.216 ± 0.492
5.407SerGlu: 5.407 ± 0.481
3.141SerPhe: 3.141 ± 0.33
4.398SerGly: 4.398 ± 0.453
1.104SerHis: 1.104 ± 0.151
5.845SerIle: 5.845 ± 0.321
8.015SerLys: 8.015 ± 1.043
6.092SerLeu: 6.092 ± 0.396
2.075SerMet: 2.075 ± 0.253
7.691SerAsn: 7.691 ± 0.798
2.113SerPro: 2.113 ± 0.236
2.266SerGln: 2.266 ± 0.268
3.465SerArg: 3.465 ± 0.339
9.995SerSer: 9.995 ± 1.03
8.32SerThr: 8.32 ± 0.697
6.53SerVal: 6.53 ± 0.322
0.343SerTrp: 0.343 ± 0.073
2.646SerTyr: 2.646 ± 0.239
0.0SerXaa: 0.0 ± 0.0
Thr
3.217ThrAla: 3.217 ± 0.309
1.009ThrCys: 1.009 ± 0.148
4.702ThrAsp: 4.702 ± 0.39
3.731ThrGlu: 3.731 ± 0.309
2.78ThrPhe: 2.78 ± 0.243
2.989ThrGly: 2.989 ± 0.36
1.466ThrHis: 1.466 ± 0.214
4.322ThrIle: 4.322 ± 0.425
4.531ThrLys: 4.531 ± 0.431
6.854ThrLeu: 6.854 ± 0.875
1.885ThrMet: 1.885 ± 0.223
5.274ThrAsn: 5.274 ± 0.502
4.36ThrPro: 4.36 ± 0.563
1.732ThrGln: 1.732 ± 0.244
2.703ThrArg: 2.703 ± 0.244
6.511ThrSer: 6.511 ± 0.695
8.015ThrThr: 8.015 ± 1.318
4.874ThrVal: 4.874 ± 0.341
0.4ThrTrp: 0.4 ± 0.097
2.075ThrTyr: 2.075 ± 0.208
0.0ThrXaa: 0.0 ± 0.0
Val
3.598ValAla: 3.598 ± 0.286
1.218ValCys: 1.218 ± 0.21
6.454ValAsp: 6.454 ± 0.423
5.064ValGlu: 5.064 ± 0.486
2.189ValPhe: 2.189 ± 0.217
2.78ValGly: 2.78 ± 0.236
1.961ValHis: 1.961 ± 0.242
3.198ValIle: 3.198 ± 0.276
4.226ValLys: 4.226 ± 0.305
4.836ValLeu: 4.836 ± 0.348
1.523ValMet: 1.523 ± 0.17
4.188ValAsn: 4.188 ± 0.362
2.646ValPro: 2.646 ± 0.221
2.741ValGln: 2.741 ± 0.27
2.818ValArg: 2.818 ± 0.255
4.531ValSer: 4.531 ± 0.377
3.37ValThr: 3.37 ± 0.269
4.664ValVal: 4.664 ± 0.353
0.343ValTrp: 0.343 ± 0.086
2.741ValTyr: 2.741 ± 0.262
0.0ValXaa: 0.0 ± 0.0
Trp
0.095TrpAla: 0.095 ± 0.035
0.152TrpCys: 0.152 ± 0.046
0.19TrpAsp: 0.19 ± 0.056
0.209TrpGlu: 0.209 ± 0.063
0.247TrpPhe: 0.247 ± 0.07
0.133TrpGly: 0.133 ± 0.054
0.152TrpHis: 0.152 ± 0.067
0.362TrpIle: 0.362 ± 0.076
0.343TrpLys: 0.343 ± 0.075
0.628TrpLeu: 0.628 ± 0.112
0.152TrpMet: 0.152 ± 0.055
0.324TrpAsn: 0.324 ± 0.086
0.114TrpPro: 0.114 ± 0.047
0.095TrpGln: 0.095 ± 0.043
0.419TrpArg: 0.419 ± 0.102
0.571TrpSer: 0.571 ± 0.091
0.324TrpThr: 0.324 ± 0.074
0.324TrpVal: 0.324 ± 0.073
0.057TrpTrp: 0.057 ± 0.038
0.305TrpTyr: 0.305 ± 0.062
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.094TyrAla: 2.094 ± 0.231
0.628TyrCys: 0.628 ± 0.145
2.437TyrAsp: 2.437 ± 0.243
2.094TyrGlu: 2.094 ± 0.171
1.276TyrPhe: 1.276 ± 0.178
1.485TyrGly: 1.485 ± 0.172
0.838TyrHis: 0.838 ± 0.125
2.189TyrIle: 2.189 ± 0.22
3.217TyrLys: 3.217 ± 0.326
2.665TyrLeu: 2.665 ± 0.294
0.971TyrMet: 0.971 ± 0.15
3.979TyrAsn: 3.979 ± 0.621
1.466TyrPro: 1.466 ± 0.202
1.028TyrGln: 1.028 ± 0.124
2.304TyrArg: 2.304 ± 0.222
2.627TyrSer: 2.627 ± 0.246
3.103TyrThr: 3.103 ± 0.266
1.771TyrVal: 1.771 ± 0.233
0.19TyrTrp: 0.19 ± 0.064
2.227TyrTyr: 2.227 ± 0.271
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 113 proteins (52527 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski