Amino acid dipepetide frequency for Marinoscillum furvescens DSM 4134

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.899AlaAla: 5.899 ± 0.078	0.67AlaCys: 0.67 ± 0.019	4.499AlaAsp: 4.499 ± 0.065	4.711AlaGlu: 4.711 ± 0.066	3.507AlaPhe: 3.507 ± 0.05	5.548AlaGly: 5.548 ± 0.057	1.467AlaHis: 1.467 ± 0.028	4.875AlaIle: 4.875 ± 0.06	3.895AlaLys: 3.895 ± 0.05	6.983AlaLeu: 6.983 ± 0.077	1.671AlaMet: 1.671 ± 0.03	3.553AlaAsn: 3.553 ± 0.054	2.698AlaPro: 2.698 ± 0.044	3.035AlaGln: 3.035 ± 0.042	2.773AlaArg: 2.773 ± 0.042	5.019AlaSer: 5.019 ± 0.067	4.382AlaThr: 4.382 ± 0.075	4.694AlaVal: 4.694 ± 0.053	0.857AlaTrp: 0.857 ± 0.024	3.05AlaTyr: 3.05 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.492CysAla: 0.492 ± 0.018	0.1CysCys: 0.1 ± 0.008	0.419CysAsp: 0.419 ± 0.019	0.493CysGlu: 0.493 ± 0.019	0.374CysPhe: 0.374 ± 0.015	0.599CysGly: 0.599 ± 0.02	0.177CysHis: 0.177 ± 0.011	0.426CysIle: 0.426 ± 0.017	0.349CysLys: 0.349 ± 0.014	0.699CysLeu: 0.699 ± 0.021	0.173CysMet: 0.173 ± 0.011	0.294CysAsn: 0.294 ± 0.012	0.297CysPro: 0.297 ± 0.014	0.296CysGln: 0.296 ± 0.013	0.25CysArg: 0.25 ± 0.013	0.509CysSer: 0.509 ± 0.015	0.451CysThr: 0.451 ± 0.017	0.435CysVal: 0.435 ± 0.018	0.096CysTrp: 0.096 ± 0.008	0.313CysTyr: 0.313 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.208AspAla: 4.208 ± 0.064	0.377AspCys: 0.377 ± 0.017	3.244AspAsp: 3.244 ± 0.06	4.228AspGlu: 4.228 ± 0.055	3.407AspPhe: 3.407 ± 0.053	4.975AspGly: 4.975 ± 0.124	1.281AspHis: 1.281 ± 0.029	3.782AspIle: 3.782 ± 0.051	2.986AspLys: 2.986 ± 0.043	5.861AspLeu: 5.861 ± 0.068	1.3AspMet: 1.3 ± 0.03	2.548AspAsn: 2.548 ± 0.051	2.609AspPro: 2.609 ± 0.047	2.755AspGln: 2.755 ± 0.044	2.516AspArg: 2.516 ± 0.037	3.373AspSer: 3.373 ± 0.071	2.881AspThr: 2.881 ± 0.058	3.841AspVal: 3.841 ± 0.048	0.947AspTrp: 0.947 ± 0.025	2.695AspTyr: 2.695 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	5.091GluAla: 5.091 ± 0.063	0.339GluCys: 0.339 ± 0.015	3.742GluAsp: 3.742 ± 0.047	4.959GluGlu: 4.959 ± 0.064	2.552GluPhe: 2.552 ± 0.038	4.412GluGly: 4.412 ± 0.051	1.315GluHis: 1.315 ± 0.031	4.482GluIle: 4.482 ± 0.054	4.166GluLys: 4.166 ± 0.059	6.963GluLeu: 6.963 ± 0.077	1.532GluMet: 1.532 ± 0.031	3.449GluAsn: 3.449 ± 0.043	2.081GluPro: 2.081 ± 0.041	2.829GluGln: 2.829 ± 0.051	2.902GluArg: 2.902 ± 0.045	3.711GluSer: 3.711 ± 0.053	3.16GluThr: 3.16 ± 0.045	5.253GluVal: 5.253 ± 0.056	0.836GluTrp: 0.836 ± 0.024	2.356GluTyr: 2.356 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.119PheAla: 3.119 ± 0.049	0.377PheCys: 0.377 ± 0.016	3.282PheAsp: 3.282 ± 0.049	3.369PheGlu: 3.369 ± 0.047	2.276PhePhe: 2.276 ± 0.043	3.548PheGly: 3.548 ± 0.045	0.936PheHis: 0.936 ± 0.025	2.811PheIle: 2.811 ± 0.045	2.387PheLys: 2.387 ± 0.04	3.98PheLeu: 3.98 ± 0.064	1.002PheMet: 1.002 ± 0.023	2.269PheAsn: 2.269 ± 0.038	1.589PhePro: 1.589 ± 0.029	1.729PheGln: 1.729 ± 0.033	1.956PheArg: 1.956 ± 0.032	3.452PheSer: 3.452 ± 0.045	3.086PheThr: 3.086 ± 0.048	2.876PheVal: 2.876 ± 0.046	0.645PheTrp: 0.645 ± 0.024	1.98PheTyr: 1.98 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	5.224GlyAla: 5.224 ± 0.07	0.652GlyCys: 0.652 ± 0.03	4.221GlyAsp: 4.221 ± 0.08	4.423GlyGlu: 4.423 ± 0.067	3.587GlyPhe: 3.587 ± 0.043	5.465GlyGly: 5.465 ± 0.081	1.345GlyHis: 1.345 ± 0.031	4.735GlyIle: 4.735 ± 0.061	4.418GlyLys: 4.418 ± 0.055	6.409GlyLeu: 6.409 ± 0.076	1.753GlyMet: 1.753 ± 0.032	3.567GlyAsn: 3.567 ± 0.06	1.878GlyPro: 1.878 ± 0.032	2.627GlyGln: 2.627 ± 0.037	2.736GlyArg: 2.736 ± 0.041	4.864GlySer: 4.864 ± 0.075	4.571GlyThr: 4.571 ± 0.075	5.192GlyVal: 5.192 ± 0.064	1.111GlyTrp: 1.111 ± 0.03	3.102GlyTyr: 3.102 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.354HisAla: 1.354 ± 0.024	0.198HisCys: 0.198 ± 0.01	1.066HisAsp: 1.066 ± 0.024	1.276HisGlu: 1.276 ± 0.026	1.227HisPhe: 1.227 ± 0.027	1.39HisGly: 1.39 ± 0.029	0.645HisHis: 0.645 ± 0.021	1.275HisIle: 1.275 ± 0.031	0.941HisLys: 0.941 ± 0.024	2.117HisLeu: 2.117 ± 0.037	0.439HisMet: 0.439 ± 0.018	0.898HisAsn: 0.898 ± 0.021	1.141HisPro: 1.141 ± 0.027	0.992HisGln: 0.992 ± 0.025	0.943HisArg: 0.943 ± 0.026	1.21HisSer: 1.21 ± 0.028	1.146HisThr: 1.146 ± 0.025	1.165HisVal: 1.165 ± 0.025	0.322HisTrp: 0.322 ± 0.014	0.96HisTyr: 0.96 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.088IleAla: 5.088 ± 0.059	0.514IleCys: 0.514 ± 0.015	4.048IleAsp: 4.048 ± 0.055	3.983IleGlu: 3.983 ± 0.05	2.592IlePhe: 2.592 ± 0.046	4.553IleGly: 4.553 ± 0.057	1.437IleHis: 1.437 ± 0.034	3.772IleIle: 3.772 ± 0.052	3.621IleLys: 3.621 ± 0.047	5.267IleLeu: 5.267 ± 0.064	1.139IleMet: 1.139 ± 0.028	3.334IleAsn: 3.334 ± 0.047	2.781IlePro: 2.781 ± 0.045	2.327IleGln: 2.327 ± 0.036	2.964IleArg: 2.964 ± 0.041	4.806IleSer: 4.806 ± 0.053	4.338IleThr: 4.338 ± 0.066	3.799IleVal: 3.799 ± 0.056	0.752IleTrp: 0.752 ± 0.022	2.518IleTyr: 2.518 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	4.456LysAla: 4.456 ± 0.056	0.295LysCys: 0.295 ± 0.011	3.259LysAsp: 3.259 ± 0.052	4.13LysGlu: 4.13 ± 0.06	2.039LysPhe: 2.039 ± 0.037	3.839LysGly: 3.839 ± 0.052	1.187LysHis: 1.187 ± 0.028	3.702LysIle: 3.702 ± 0.044	4.029LysLys: 4.029 ± 0.069	5.309LysLeu: 5.309 ± 0.059	1.477LysMet: 1.477 ± 0.028	2.999LysAsn: 2.999 ± 0.039	2.283LysPro: 2.283 ± 0.043	2.082LysGln: 2.082 ± 0.038	2.449LysArg: 2.449 ± 0.04	3.732LysSer: 3.732 ± 0.051	3.114LysThr: 3.114 ± 0.045	3.952LysVal: 3.952 ± 0.054	0.789LysTrp: 0.789 ± 0.022	2.233LysTyr: 2.233 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	7.078LeuAla: 7.078 ± 0.082	0.69LeuCys: 0.69 ± 0.022	5.638LeuAsp: 5.638 ± 0.065	6.218LeuGlu: 6.218 ± 0.061	4.102LeuPhe: 4.102 ± 0.054	6.02LeuGly: 6.02 ± 0.063	1.797LeuHis: 1.797 ± 0.03	6.128LeuIle: 6.128 ± 0.076	6.112LeuLys: 6.112 ± 0.072	8.913LeuLeu: 8.913 ± 0.104	2.269LeuMet: 2.269 ± 0.04	4.59LeuAsn: 4.59 ± 0.059	4.002LeuPro: 4.002 ± 0.049	3.579LeuGln: 3.579 ± 0.049	3.817LeuArg: 3.817 ± 0.049	7.014LeuSer: 7.014 ± 0.061	5.891LeuThr: 5.891 ± 0.064	5.893LeuVal: 5.893 ± 0.07	1.082LeuTrp: 1.082 ± 0.032	3.3LeuTyr: 3.3 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	1.795MetAla: 1.795 ± 0.035	0.126MetCys: 0.126 ± 0.009	1.361MetAsp: 1.361 ± 0.024	1.439MetGlu: 1.439 ± 0.029	0.694MetPhe: 0.694 ± 0.021	1.517MetGly: 1.517 ± 0.031	0.43MetHis: 0.43 ± 0.016	1.428MetIle: 1.428 ± 0.034	1.831MetLys: 1.831 ± 0.034	2.053MetLeu: 2.053 ± 0.035	0.575MetMet: 0.575 ± 0.018	1.13MetAsn: 1.13 ± 0.023	0.916MetPro: 0.916 ± 0.025	0.808MetGln: 0.808 ± 0.023	1.025MetArg: 1.025 ± 0.024	1.436MetSer: 1.436 ± 0.03	1.246MetThr: 1.246 ± 0.026	1.544MetVal: 1.544 ± 0.032	0.212MetTrp: 0.212 ± 0.012	0.706MetTyr: 0.706 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.512AsnAla: 3.512 ± 0.049	0.339AsnCys: 0.339 ± 0.014	2.894AsnAsp: 2.894 ± 0.062	3.163AsnGlu: 3.163 ± 0.041	2.219AsnPhe: 2.219 ± 0.039	3.94AsnGly: 3.94 ± 0.064	1.055AsnHis: 1.055 ± 0.024	3.069AsnIle: 3.069 ± 0.043	2.45AsnLys: 2.45 ± 0.038	4.63AsnLeu: 4.63 ± 0.057	0.999AsnMet: 0.999 ± 0.024	2.463AsnAsn: 2.463 ± 0.05	2.648AsnPro: 2.648 ± 0.041	2.148AsnGln: 2.148 ± 0.036	2.085AsnArg: 2.085 ± 0.033	3.076AsnSer: 3.076 ± 0.049	3.029AsnThr: 3.029 ± 0.053	2.895AsnVal: 2.895 ± 0.044	0.755AsnTrp: 0.755 ± 0.023	2.302AsnTyr: 2.302 ± 0.04	0.0AsnXaa: 0.0 ± 0.0
Pro	2.931ProAla: 2.931 ± 0.044	0.186ProCys: 0.186 ± 0.013	2.801ProAsp: 2.801 ± 0.048	3.424ProGlu: 3.424 ± 0.051	1.889ProPhe: 1.889 ± 0.036	2.788ProGly: 2.788 ± 0.04	0.835ProHis: 0.835 ± 0.025	2.276ProIle: 2.276 ± 0.041	2.117ProLys: 2.117 ± 0.041	3.152ProLeu: 3.152 ± 0.046	0.793ProMet: 0.793 ± 0.022	2.198ProAsn: 2.198 ± 0.037	1.149ProPro: 1.149 ± 0.034	1.412ProGln: 1.412 ± 0.025	1.273ProArg: 1.273 ± 0.03	2.41ProSer: 2.41 ± 0.041	2.293ProThr: 2.293 ± 0.039	2.961ProVal: 2.961 ± 0.047	0.523ProTrp: 0.523 ± 0.02	1.511ProTyr: 1.511 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	2.9GlnAla: 2.9 ± 0.044	0.213GlnCys: 0.213 ± 0.011	2.025GlnAsp: 2.025 ± 0.035	2.614GlnGlu: 2.614 ± 0.051	1.606GlnPhe: 1.606 ± 0.031	2.348GlnGly: 2.348 ± 0.042	0.847GlnHis: 0.847 ± 0.022	2.412GlnIle: 2.412 ± 0.032	2.441GlnLys: 2.441 ± 0.042	4.276GlnLeu: 4.276 ± 0.047	0.914GlnMet: 0.914 ± 0.02	2.02GlnAsn: 2.02 ± 0.035	1.539GlnPro: 1.539 ± 0.028	1.971GlnGln: 1.971 ± 0.041	1.663GlnArg: 1.663 ± 0.032	2.48GlnSer: 2.48 ± 0.037	2.092GlnThr: 2.092 ± 0.037	2.777GlnVal: 2.777 ± 0.042	0.574GlnTrp: 0.574 ± 0.02	1.507GlnTyr: 1.507 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	2.701ArgAla: 2.701 ± 0.042	0.236ArgCys: 0.236 ± 0.012	2.165ArgAsp: 2.165 ± 0.036	2.688ArgGlu: 2.688 ± 0.045	2.2ArgPhe: 2.2 ± 0.037	2.322ArgGly: 2.322 ± 0.038	0.847ArgHis: 0.847 ± 0.023	2.924ArgIle: 2.924 ± 0.041	2.797ArgLys: 2.797 ± 0.044	4.138ArgLeu: 4.138 ± 0.056	1.124ArgMet: 1.124 ± 0.027	2.076ArgAsn: 2.076 ± 0.031	1.478ArgPro: 1.478 ± 0.027	1.618ArgGln: 1.618 ± 0.03	1.798ArgArg: 1.798 ± 0.037	2.662ArgSer: 2.662 ± 0.04	2.211ArgThr: 2.211 ± 0.035	2.796ArgVal: 2.796 ± 0.04	0.647ArgTrp: 0.647 ± 0.018	1.892ArgTyr: 1.892 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	4.776SerAla: 4.776 ± 0.063	0.567SerCys: 0.567 ± 0.017	3.965SerAsp: 3.965 ± 0.071	4.183SerGlu: 4.183 ± 0.052	3.473SerPhe: 3.473 ± 0.048	5.708SerGly: 5.708 ± 0.082	1.297SerHis: 1.297 ± 0.027	4.388SerIle: 4.388 ± 0.055	3.515SerLys: 3.515 ± 0.051	6.342SerLeu: 6.342 ± 0.064	1.442SerMet: 1.442 ± 0.031	3.318SerAsn: 3.318 ± 0.05	2.516SerPro: 2.516 ± 0.039	2.357SerGln: 2.357 ± 0.042	2.677SerArg: 2.677 ± 0.038	4.776SerSer: 4.776 ± 0.076	3.763SerThr: 3.763 ± 0.058	4.335SerVal: 4.335 ± 0.055	0.97SerTrp: 0.97 ± 0.024	2.869SerTyr: 2.869 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	4.41ThrAla: 4.41 ± 0.067	0.401ThrCys: 0.401 ± 0.016	3.677ThrAsp: 3.677 ± 0.069	3.305ThrGlu: 3.305 ± 0.047	2.952ThrPhe: 2.952 ± 0.053	4.592ThrGly: 4.592 ± 0.063	1.212ThrHis: 1.212 ± 0.027	4.038ThrIle: 4.038 ± 0.061	2.611ThrLys: 2.611 ± 0.037	5.647ThrLeu: 5.647 ± 0.062	1.023ThrMet: 1.023 ± 0.022	2.911ThrAsn: 2.911 ± 0.055	2.626ThrPro: 2.626 ± 0.046	1.89ThrGln: 1.89 ± 0.032	2.105ThrArg: 2.105 ± 0.036	4.076ThrSer: 4.076 ± 0.075	3.591ThrThr: 3.591 ± 0.062	4.202ThrVal: 4.202 ± 0.079	0.784ThrTrp: 0.784 ± 0.023	2.67ThrTyr: 2.67 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	5.159ValAla: 5.159 ± 0.064	0.533ValCys: 0.533 ± 0.02	4.009ValAsp: 4.009 ± 0.058	4.038ValGlu: 4.038 ± 0.05	3.157ValPhe: 3.157 ± 0.046	4.541ValGly: 4.541 ± 0.061	1.246ValHis: 1.246 ± 0.025	4.288ValIle: 4.288 ± 0.057	3.795ValLys: 3.795 ± 0.057	6.115ValLeu: 6.115 ± 0.074	1.48ValMet: 1.48 ± 0.033	3.334ValAsn: 3.334 ± 0.049	2.603ValPro: 2.603 ± 0.044	2.179ValGln: 2.179 ± 0.034	2.786ValArg: 2.786 ± 0.042	5.038ValSer: 5.038 ± 0.066	4.177ValThr: 4.177 ± 0.075	4.879ValVal: 4.879 ± 0.055	0.824ValTrp: 0.824 ± 0.024	2.548ValTyr: 2.548 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.843TrpAla: 0.843 ± 0.023	0.106TrpCys: 0.106 ± 0.008	0.856TrpAsp: 0.856 ± 0.027	0.88TrpGlu: 0.88 ± 0.026	0.553TrpPhe: 0.553 ± 0.021	0.96TrpGly: 0.96 ± 0.025	0.342TrpHis: 0.342 ± 0.014	0.759TrpIle: 0.759 ± 0.023	0.905TrpLys: 0.905 ± 0.022	1.191TrpLeu: 1.191 ± 0.029	0.387TrpMet: 0.387 ± 0.016	0.752TrpAsn: 0.752 ± 0.021	0.431TrpPro: 0.431 ± 0.017	0.6TrpGln: 0.6 ± 0.019	0.566TrpArg: 0.566 ± 0.019	0.972TrpSer: 0.972 ± 0.024	0.745TrpThr: 0.745 ± 0.023	0.926TrpVal: 0.926 ± 0.025	0.241TrpTrp: 0.241 ± 0.012	0.566TrpTyr: 0.566 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.75TyrAla: 2.75 ± 0.046	0.323TyrCys: 0.323 ± 0.014	2.645TyrAsp: 2.645 ± 0.043	2.604TyrGlu: 2.604 ± 0.037	2.265TyrPhe: 2.265 ± 0.039	2.817TyrGly: 2.817 ± 0.045	1.007TyrHis: 1.007 ± 0.023	2.062TyrIle: 2.062 ± 0.042	1.99TyrLys: 1.99 ± 0.034	4.087TyrLeu: 4.087 ± 0.058	0.778TyrMet: 0.778 ± 0.02	1.967TyrAsn: 1.967 ± 0.042	1.654TyrPro: 1.654 ± 0.034	1.985TyrGln: 1.985 ± 0.03	2.041TyrArg: 2.041 ± 0.037	2.621TyrSer: 2.621 ± 0.042	2.554TyrThr: 2.554 ± 0.045	2.315TyrVal: 2.315 ± 0.035	0.612TyrTrp: 0.612 ± 0.021	1.893TyrTyr: 1.893 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4702 proteins (1798820 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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