Amino acid dipepetide frequency for Torque teno tamarin virus (isolate So-TTV2)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.654AlaAla: 8.654 ± 8.038
0.0AlaCys: 0.0 ± 0.0
3.846AlaAsp: 3.846 ± 1.767
2.885AlaGlu: 2.885 ± 1.11
1.923AlaPhe: 1.923 ± 1.151
10.577AlaGly: 10.577 ± 4.175
2.885AlaHis: 2.885 ± 2.752
0.962AlaIle: 0.962 ± 0.495
1.923AlaLys: 1.923 ± 0.991
4.808AlaLeu: 4.808 ± 1.007
0.962AlaMet: 0.962 ± 1.381
0.962AlaAsn: 0.962 ± 0.495
2.885AlaPro: 2.885 ± 0.918
3.846AlaGln: 3.846 ± 1.982
2.885AlaArg: 2.885 ± 1.486
0.962AlaSer: 0.962 ± 0.495
2.885AlaThr: 2.885 ± 3.11
0.0AlaVal: 0.0 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
1.923AlaTyr: 1.923 ± 1.369
0.0AlaXaa: 0.0 ± 0.0
Cys
0.962CysAla: 0.962 ± 0.495
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.962CysLys: 0.962 ± 1.578
0.962CysLeu: 0.962 ± 0.495
1.923CysMet: 1.923 ± 1.151
1.923CysAsn: 1.923 ± 1.151
0.962CysPro: 0.962 ± 0.495
2.885CysGln: 2.885 ± 2.012
1.923CysArg: 1.923 ± 1.192
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.962CysTrp: 0.962 ± 0.495
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.885AspAla: 2.885 ± 2.494
0.0AspCys: 0.0 ± 0.0
0.0AspAsp: 0.0 ± 0.0
4.808AspGlu: 4.808 ± 1.266
0.962AspPhe: 0.962 ± 0.495
3.846AspGly: 3.846 ± 4.708
0.962AspHis: 0.962 ± 0.495
3.846AspIle: 3.846 ± 1.982
2.885AspLys: 2.885 ± 1.486
4.808AspLeu: 4.808 ± 2.477
0.962AspMet: 0.962 ± 0.495
7.692AspAsn: 7.692 ± 2.081
5.769AspPro: 5.769 ± 1.657
0.962AspGln: 0.962 ± 0.495
1.923AspArg: 1.923 ± 0.991
5.769AspSer: 5.769 ± 5.504
1.923AspThr: 1.923 ± 3.156
2.885AspVal: 2.885 ± 1.11
1.923AspTrp: 1.923 ± 1.369
3.846AspTyr: 3.846 ± 0.869
0.0AspXaa: 0.0 ± 0.0
Glu
0.962GluAla: 0.962 ± 0.495
1.923GluCys: 1.923 ± 1.369
5.769GluAsp: 5.769 ± 3.944
4.808GluGlu: 4.808 ± 2.872
0.962GluPhe: 0.962 ± 0.495
4.808GluGly: 4.808 ± 2.207
0.962GluHis: 0.962 ± 0.495
0.962GluIle: 0.962 ± 0.495
2.885GluLys: 2.885 ± 1.486
3.846GluLeu: 3.846 ± 3.011
0.0GluMet: 0.0 ± 0.0
2.885GluAsn: 2.885 ± 1.333
2.885GluPro: 2.885 ± 2.494
0.0GluGln: 0.0 ± 0.0
1.923GluArg: 1.923 ± 1.192
2.885GluSer: 2.885 ± 1.984
7.692GluThr: 7.692 ± 1.737
0.962GluVal: 0.962 ± 0.495
0.0GluTrp: 0.0 ± 0.0
0.962GluTyr: 0.962 ± 1.578
0.0GluXaa: 0.0 ± 0.0
Phe
2.885PheAla: 2.885 ± 1.486
1.923PheCys: 1.923 ± 1.151
0.962PheAsp: 0.962 ± 0.495
0.962PheGlu: 0.962 ± 1.381
0.962PhePhe: 0.962 ± 0.495
0.962PheGly: 0.962 ± 0.495
0.962PheHis: 0.962 ± 1.569
1.923PheIle: 1.923 ± 0.991
1.923PheLys: 1.923 ± 1.369
0.962PheLeu: 0.962 ± 0.495
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
2.885PhePro: 2.885 ± 1.486
0.962PheGln: 0.962 ± 0.495
1.923PheArg: 1.923 ± 0.991
0.962PheSer: 0.962 ± 0.495
1.923PheThr: 1.923 ± 1.369
0.0PheVal: 0.0 ± 0.0
0.962PheTrp: 0.962 ± 0.495
0.962PheTyr: 0.962 ± 0.495
0.0PheXaa: 0.0 ± 0.0
Gly
4.808GlyAla: 4.808 ± 6.113
0.962GlyCys: 0.962 ± 1.578
6.731GlyAsp: 6.731 ± 1.959
6.731GlyGlu: 6.731 ± 5.482
0.962GlyPhe: 0.962 ± 0.495
8.654GlyGly: 8.654 ± 4.667
1.923GlyHis: 1.923 ± 0.991
3.846GlyIle: 3.846 ± 1.278
2.885GlyLys: 2.885 ± 1.486
3.846GlyLeu: 3.846 ± 1.982
0.962GlyMet: 0.962 ± 2.183
2.885GlyAsn: 2.885 ± 1.486
2.885GlyPro: 2.885 ± 0.918
0.962GlyGln: 0.962 ± 0.495
8.654GlyArg: 8.654 ± 0.809
3.846GlySer: 3.846 ± 0.869
1.923GlyThr: 1.923 ± 1.192
0.0GlyVal: 0.0 ± 0.0
0.962GlyTrp: 0.962 ± 0.495
2.885GlyTyr: 2.885 ± 1.486
0.0GlyXaa: 0.0 ± 0.0
His
0.962HisAla: 0.962 ± 0.495
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.962HisGlu: 0.962 ± 0.495
0.962HisPhe: 0.962 ± 0.495
1.923HisGly: 1.923 ± 1.151
0.962HisHis: 0.962 ± 0.495
0.0HisIle: 0.0 ± 0.0
2.885HisLys: 2.885 ± 3.679
2.885HisLeu: 2.885 ± 1.486
0.0HisMet: 0.0 ± 0.0
0.962HisAsn: 0.962 ± 0.495
2.885HisPro: 2.885 ± 2.903
0.0HisGln: 0.0 ± 0.0
3.846HisArg: 3.846 ± 1.982
2.885HisSer: 2.885 ± 1.333
1.923HisThr: 1.923 ± 0.991
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.962HisTyr: 0.962 ± 1.381
0.0HisXaa: 0.0 ± 0.0
Ile
1.923IleAla: 1.923 ± 0.991
1.923IleCys: 1.923 ± 1.151
2.885IleAsp: 2.885 ± 1.486
0.962IleGlu: 0.962 ± 0.495
0.0IlePhe: 0.0 ± 0.0
0.962IleGly: 0.962 ± 1.381
0.962IleHis: 0.962 ± 0.495
1.923IleIle: 1.923 ± 0.991
2.885IleLys: 2.885 ± 1.486
3.846IleLeu: 3.846 ± 1.982
0.0IleMet: 0.0 ± 0.0
2.885IleAsn: 2.885 ± 1.333
3.846IlePro: 3.846 ± 1.982
0.962IleGln: 0.962 ± 0.495
2.885IleArg: 2.885 ± 0.918
0.0IleSer: 0.0 ± 0.0
1.923IleThr: 1.923 ± 0.991
3.846IleVal: 3.846 ± 1.982
0.962IleTrp: 0.962 ± 1.381
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.923LysAla: 1.923 ± 0.991
0.962LysCys: 0.962 ± 0.495
6.731LysAsp: 6.731 ± 2.51
3.846LysGlu: 3.846 ± 1.278
0.0LysPhe: 0.0 ± 0.0
0.962LysGly: 0.962 ± 1.578
0.962LysHis: 0.962 ± 0.495
2.885LysIle: 2.885 ± 0.918
6.731LysLys: 6.731 ± 1.718
4.808LysLeu: 4.808 ± 1.007
0.962LysMet: 0.962 ± 0.495
4.808LysAsn: 4.808 ± 2.477
1.923LysPro: 1.923 ± 2.416
0.962LysGln: 0.962 ± 0.495
6.731LysArg: 6.731 ± 5.125
1.923LysSer: 1.923 ± 0.991
8.654LysThr: 8.654 ± 3.127
0.962LysVal: 0.962 ± 0.495
4.808LysTrp: 4.808 ± 2.477
1.923LysTyr: 1.923 ± 0.991
0.0LysXaa: 0.0 ± 0.0
Leu
5.769LeuAla: 5.769 ± 1.976
0.0LeuCys: 0.0 ± 0.0
2.885LeuAsp: 2.885 ± 2.903
0.962LeuGlu: 0.962 ± 1.578
3.846LeuPhe: 3.846 ± 1.278
4.808LeuGly: 4.808 ± 2.477
0.962LeuHis: 0.962 ± 0.495
1.923LeuIle: 1.923 ± 2.763
3.846LeuLys: 3.846 ± 1.982
8.654LeuLeu: 8.654 ± 2.772
2.885LeuMet: 2.885 ± 0.787
2.885LeuAsn: 2.885 ± 1.11
4.808LeuPro: 4.808 ± 2.069
1.923LeuGln: 1.923 ± 0.991
7.692LeuArg: 7.692 ± 2.971
0.0LeuSer: 0.0 ± 0.0
6.731LeuThr: 6.731 ± 2.766
0.962LeuVal: 0.962 ± 1.381
2.885LeuTrp: 2.885 ± 1.333
3.846LeuTyr: 3.846 ± 1.982
0.0LeuXaa: 0.0 ± 0.0
Met
2.885MetAla: 2.885 ± 1.11
0.0MetCys: 0.0 ± 0.0
1.923MetAsp: 1.923 ± 1.151
0.962MetGlu: 0.962 ± 0.495
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.962MetIle: 0.962 ± 0.495
0.962MetLys: 0.962 ± 0.495
1.923MetLeu: 1.923 ± 1.369
0.962MetMet: 0.962 ± 0.495
1.923MetAsn: 1.923 ± 0.991
2.885MetPro: 2.885 ± 1.486
1.923MetGln: 1.923 ± 1.151
0.0MetArg: 0.0 ± 0.0
1.923MetSer: 1.923 ± 0.991
2.885MetThr: 2.885 ± 1.984
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.962AsnAla: 0.962 ± 0.495
0.962AsnCys: 0.962 ± 1.381
0.962AsnAsp: 0.962 ± 0.495
0.0AsnGlu: 0.0 ± 0.0
0.962AsnPhe: 0.962 ± 1.569
1.923AsnGly: 1.923 ± 0.991
2.885AsnHis: 2.885 ± 1.11
2.885AsnIle: 2.885 ± 1.486
2.885AsnLys: 2.885 ± 1.486
3.846AsnLeu: 3.846 ± 1.389
2.885AsnMet: 2.885 ± 1.486
0.0AsnAsn: 0.0 ± 0.0
0.962AsnPro: 0.962 ± 0.495
2.885AsnGln: 2.885 ± 1.333
4.808AsnArg: 4.808 ± 1.588
2.885AsnSer: 2.885 ± 1.826
4.808AsnThr: 4.808 ± 2.477
4.808AsnVal: 4.808 ± 2.477
2.885AsnTrp: 2.885 ± 1.333
2.885AsnTyr: 2.885 ± 1.486
0.0AsnXaa: 0.0 ± 0.0
Pro
2.885ProAla: 2.885 ± 1.826
0.962ProCys: 0.962 ± 0.495
0.962ProAsp: 0.962 ± 0.495
7.692ProGlu: 7.692 ± 2.947
2.885ProPhe: 2.885 ± 1.333
4.808ProGly: 4.808 ± 1.007
0.962ProHis: 0.962 ± 0.495
2.885ProIle: 2.885 ± 1.486
5.769ProLys: 5.769 ± 3.576
2.885ProLeu: 2.885 ± 0.918
3.846ProMet: 3.846 ± 1.391
2.885ProAsn: 2.885 ± 0.918
8.654ProPro: 8.654 ± 4.565
5.769ProGln: 5.769 ± 2.318
4.808ProArg: 4.808 ± 2.872
0.962ProSer: 0.962 ± 0.495
3.846ProThr: 3.846 ± 4.325
2.885ProVal: 2.885 ± 1.486
4.808ProTrp: 4.808 ± 1.639
3.846ProTyr: 3.846 ± 1.982
0.0ProXaa: 0.0 ± 0.0
Gln
1.923GlnAla: 1.923 ± 0.991
0.0GlnCys: 0.0 ± 0.0
0.962GlnAsp: 0.962 ± 1.578
1.923GlnGlu: 1.923 ± 1.151
0.962GlnPhe: 0.962 ± 0.495
1.923GlnGly: 1.923 ± 1.369
0.962GlnHis: 0.962 ± 0.495
0.962GlnIle: 0.962 ± 0.495
2.885GlnLys: 2.885 ± 1.333
0.962GlnLeu: 0.962 ± 0.495
0.962GlnMet: 0.962 ± 0.495
5.769GlnAsn: 5.769 ± 2.221
0.0GlnPro: 0.0 ± 0.0
1.923GlnGln: 1.923 ± 0.991
4.808GlnArg: 4.808 ± 2.758
2.885GlnSer: 2.885 ± 1.984
3.846GlnThr: 3.846 ± 1.982
0.962GlnVal: 0.962 ± 0.495
1.923GlnTrp: 1.923 ± 0.991
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.808ArgAla: 4.808 ± 2.069
0.962ArgCys: 0.962 ± 0.495
3.846ArgAsp: 3.846 ± 0.869
4.808ArgGlu: 4.808 ± 1.007
0.962ArgPhe: 0.962 ± 0.495
4.808ArgGly: 4.808 ± 1.077
3.846ArgHis: 3.846 ± 1.473
1.923ArgIle: 1.923 ± 1.369
7.692ArgLys: 7.692 ± 7.436
6.731ArgLeu: 6.731 ± 1.907
0.962ArgMet: 0.962 ± 0.49
1.923ArgAsn: 1.923 ± 0.991
10.577ArgPro: 10.577 ± 4.172
4.808ArgGln: 4.808 ± 2.069
35.577ArgArg: 35.577 ± 6.537
2.885ArgSer: 2.885 ± 2.752
4.808ArgThr: 4.808 ± 2.614
5.769ArgVal: 5.769 ± 2.973
6.731ArgTrp: 6.731 ± 3.468
2.885ArgTyr: 2.885 ± 1.486
0.0ArgXaa: 0.0 ± 0.0
Ser
2.885SerAla: 2.885 ± 1.984
0.0SerCys: 0.0 ± 0.0
5.769SerAsp: 5.769 ± 3.576
1.923SerGlu: 1.923 ± 3.156
1.923SerPhe: 1.923 ± 1.369
0.0SerGly: 0.0 ± 0.0
0.962SerHis: 0.962 ± 1.381
1.923SerIle: 1.923 ± 0.991
2.885SerLys: 2.885 ± 1.486
3.846SerLeu: 3.846 ± 1.473
0.962SerMet: 0.962 ± 0.495
0.962SerAsn: 0.962 ± 0.495
5.769SerPro: 5.769 ± 1.836
0.0SerGln: 0.0 ± 0.0
3.846SerArg: 3.846 ± 2.384
4.808SerSer: 4.808 ± 2.069
3.846SerThr: 3.846 ± 2.384
0.962SerVal: 0.962 ± 0.495
4.808SerTrp: 4.808 ± 4.795
0.962SerTyr: 0.962 ± 0.495
0.0SerXaa: 0.0 ± 0.0
Thr
5.769ThrAla: 5.769 ± 2.318
0.962ThrCys: 0.962 ± 0.495
3.846ThrAsp: 3.846 ± 2.384
1.923ThrGlu: 1.923 ± 1.192
0.962ThrPhe: 0.962 ± 0.495
5.769ThrGly: 5.769 ± 1.657
1.923ThrHis: 1.923 ± 1.369
0.962ThrIle: 0.962 ± 0.495
4.808ThrLys: 4.808 ± 2.477
5.769ThrLeu: 5.769 ± 2.105
0.0ThrMet: 0.0 ± 0.0
3.846ThrAsn: 3.846 ± 1.982
6.731ThrPro: 6.731 ± 2.472
4.808ThrGln: 4.808 ± 1.639
8.654ThrArg: 8.654 ± 4.436
5.769ThrSer: 5.769 ± 7.477
7.692ThrThr: 7.692 ± 6.688
0.0ThrVal: 0.0 ± 0.0
2.885ThrTrp: 2.885 ± 1.333
3.846ThrTyr: 3.846 ± 2.384
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
0.962ValAsp: 0.962 ± 1.381
0.962ValGlu: 0.962 ± 0.495
3.846ValPhe: 3.846 ± 1.982
1.923ValGly: 1.923 ± 0.991
0.962ValHis: 0.962 ± 1.381
1.923ValIle: 1.923 ± 0.991
1.923ValLys: 1.923 ± 0.991
0.962ValLeu: 0.962 ± 0.495
0.962ValMet: 0.962 ± 0.495
0.962ValAsn: 0.962 ± 0.495
0.962ValPro: 0.962 ± 0.495
0.0ValGln: 0.0 ± 0.0
3.846ValArg: 3.846 ± 1.982
1.923ValSer: 1.923 ± 0.991
4.808ValThr: 4.808 ± 1.077
3.846ValVal: 3.846 ± 1.982
0.962ValTrp: 0.962 ± 0.495
1.923ValTyr: 1.923 ± 0.991
0.0ValXaa: 0.0 ± 0.0
Trp
1.923TrpAla: 1.923 ± 1.369
0.0TrpCys: 0.0 ± 0.0
1.923TrpAsp: 1.923 ± 0.991
0.0TrpGlu: 0.0 ± 0.0
0.962TrpPhe: 0.962 ± 0.495
6.731TrpGly: 6.731 ± 2.766
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.885TrpLys: 2.885 ± 1.11
0.962TrpLeu: 0.962 ± 1.569
0.962TrpMet: 0.962 ± 0.495
0.962TrpAsn: 0.962 ± 1.578
2.885TrpPro: 2.885 ± 0.918
0.0TrpGln: 0.0 ± 0.0
8.654TrpArg: 8.654 ± 2.421
3.846TrpSer: 3.846 ± 1.473
3.846TrpThr: 3.846 ± 1.982
1.923TrpVal: 1.923 ± 1.192
0.962TrpTrp: 0.962 ± 0.495
2.885TrpTyr: 2.885 ± 1.486
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.923TyrCys: 1.923 ± 1.192
7.692TyrAsp: 7.692 ± 3.964
0.962TyrGlu: 0.962 ± 1.578
0.962TyrPhe: 0.962 ± 0.495
2.885TyrGly: 2.885 ± 0.918
0.962TyrHis: 0.962 ± 0.495
2.885TyrIle: 2.885 ± 1.486
0.962TyrLys: 0.962 ± 0.495
0.962TyrLeu: 0.962 ± 1.569
0.0TyrMet: 0.0 ± 0.0
0.962TyrAsn: 0.962 ± 0.495
3.846TyrPro: 3.846 ± 0.869
0.962TyrGln: 0.962 ± 0.495
1.923TyrArg: 1.923 ± 1.151
1.923TyrSer: 1.923 ± 0.991
0.962TyrThr: 0.962 ± 0.495
2.885TyrVal: 2.885 ± 1.486
2.885TyrTrp: 2.885 ± 1.486
1.923TyrTyr: 1.923 ± 3.156
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1041 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski