Amino acid dipepetide frequency for Arthronema virus TR020

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.484AlaAla: 6.484 ± 1.143
0.219AlaCys: 0.219 ± 0.162
4.444AlaAsp: 4.444 ± 0.705
4.371AlaGlu: 4.371 ± 0.486
3.57AlaPhe: 3.57 ± 0.526
4.735AlaGly: 4.735 ± 0.653
1.457AlaHis: 1.457 ± 0.328
3.642AlaIle: 3.642 ± 0.472
4.371AlaLys: 4.371 ± 0.529
8.596AlaLeu: 8.596 ± 1.027
2.55AlaMet: 2.55 ± 0.518
4.444AlaAsn: 4.444 ± 0.751
2.258AlaPro: 2.258 ± 0.489
3.424AlaGln: 3.424 ± 0.687
2.914AlaArg: 2.914 ± 0.438
5.318AlaSer: 5.318 ± 0.756
4.662AlaThr: 4.662 ± 0.508
5.609AlaVal: 5.609 ± 0.444
0.219AlaTrp: 0.219 ± 0.117
2.331AlaTyr: 2.331 ± 0.395
0.0AlaXaa: 0.0 ± 0.0
Cys
0.219CysAla: 0.219 ± 0.121
0.073CysCys: 0.073 ± 0.072
0.291CysAsp: 0.291 ± 0.141
0.073CysGlu: 0.073 ± 0.074
0.291CysPhe: 0.291 ± 0.17
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.219CysIle: 0.219 ± 0.128
0.364CysLys: 0.364 ± 0.214
0.291CysLeu: 0.291 ± 0.135
0.0CysMet: 0.0 ± 0.0
0.146CysAsn: 0.146 ± 0.154
0.437CysPro: 0.437 ± 0.176
0.146CysGln: 0.146 ± 0.101
0.146CysArg: 0.146 ± 0.099
0.073CysSer: 0.073 ± 0.065
0.437CysThr: 0.437 ± 0.216
0.437CysVal: 0.437 ± 0.195
0.073CysTrp: 0.073 ± 0.075
0.146CysTyr: 0.146 ± 0.134
0.0CysXaa: 0.0 ± 0.0
Asp
4.225AspAla: 4.225 ± 0.634
0.219AspCys: 0.219 ± 0.126
4.08AspAsp: 4.08 ± 0.651
5.391AspGlu: 5.391 ± 0.682
2.841AspPhe: 2.841 ± 0.408
3.133AspGly: 3.133 ± 0.474
0.219AspHis: 0.219 ± 0.126
4.517AspIle: 4.517 ± 0.643
2.987AspLys: 2.987 ± 0.473
5.391AspLeu: 5.391 ± 0.677
1.748AspMet: 1.748 ± 0.337
3.497AspAsn: 3.497 ± 0.484
3.424AspPro: 3.424 ± 0.858
0.947AspGln: 0.947 ± 0.309
2.914AspArg: 2.914 ± 0.489
3.861AspSer: 3.861 ± 0.41
3.57AspThr: 3.57 ± 0.492
4.662AspVal: 4.662 ± 0.807
0.947AspTrp: 0.947 ± 0.312
2.623AspTyr: 2.623 ± 0.364
0.0AspXaa: 0.0 ± 0.0
Glu
5.391GluAla: 5.391 ± 0.682
0.219GluCys: 0.219 ± 0.135
3.861GluAsp: 3.861 ± 0.61
3.497GluGlu: 3.497 ± 0.752
2.914GluPhe: 2.914 ± 0.482
3.715GluGly: 3.715 ± 0.459
0.801GluHis: 0.801 ± 0.288
2.914GluIle: 2.914 ± 0.546
2.695GluLys: 2.695 ± 0.425
8.086GluLeu: 8.086 ± 1.069
1.02GluMet: 1.02 ± 0.282
2.914GluAsn: 2.914 ± 0.451
1.821GluPro: 1.821 ± 0.431
3.788GluGln: 3.788 ± 0.586
4.08GluArg: 4.08 ± 0.609
4.371GluSer: 4.371 ± 0.636
4.444GluThr: 4.444 ± 0.705
4.517GluVal: 4.517 ± 0.679
1.093GluTrp: 1.093 ± 0.32
3.06GluTyr: 3.06 ± 0.5
0.0GluXaa: 0.0 ± 0.0
Phe
2.185PheAla: 2.185 ± 0.448
0.219PheCys: 0.219 ± 0.124
3.133PheAsp: 3.133 ± 0.43
2.331PheGlu: 2.331 ± 0.528
1.02PhePhe: 1.02 ± 0.305
2.404PheGly: 2.404 ± 0.482
0.219PheHis: 0.219 ± 0.114
2.914PheIle: 2.914 ± 0.447
1.967PheLys: 1.967 ± 0.473
3.133PheLeu: 3.133 ± 0.504
0.728PheMet: 0.728 ± 0.18
2.987PheAsn: 2.987 ± 0.631
1.457PhePro: 1.457 ± 0.34
1.166PheGln: 1.166 ± 0.247
1.821PheArg: 1.821 ± 0.322
2.55PheSer: 2.55 ± 0.485
2.987PheThr: 2.987 ± 0.52
2.768PheVal: 2.768 ± 0.48
0.146PheTrp: 0.146 ± 0.103
1.821PheTyr: 1.821 ± 0.486
0.0PheXaa: 0.0 ± 0.0
Gly
4.517GlyAla: 4.517 ± 0.806
0.146GlyCys: 0.146 ± 0.093
3.642GlyAsp: 3.642 ± 0.549
4.298GlyGlu: 4.298 ± 0.573
2.987GlyPhe: 2.987 ± 0.302
4.371GlyGly: 4.371 ± 0.591
1.238GlyHis: 1.238 ± 0.314
3.788GlyIle: 3.788 ± 0.533
3.133GlyLys: 3.133 ± 0.598
5.391GlyLeu: 5.391 ± 0.716
1.821GlyMet: 1.821 ± 0.442
3.497GlyAsn: 3.497 ± 0.394
0.0GlyPro: 0.0 ± 0.0
3.424GlyGln: 3.424 ± 0.559
3.424GlyArg: 3.424 ± 0.576
6.119GlySer: 6.119 ± 0.792
4.371GlyThr: 4.371 ± 0.489
4.444GlyVal: 4.444 ± 0.691
0.583GlyTrp: 0.583 ± 0.237
3.205GlyTyr: 3.205 ± 0.662
0.0GlyXaa: 0.0 ± 0.0
His
0.728HisAla: 0.728 ± 0.189
0.073HisCys: 0.073 ± 0.07
1.53HisAsp: 1.53 ± 0.346
1.093HisGlu: 1.093 ± 0.311
0.801HisPhe: 0.801 ± 0.266
1.384HisGly: 1.384 ± 0.34
0.364HisHis: 0.364 ± 0.179
1.093HisIle: 1.093 ± 0.288
0.656HisLys: 0.656 ± 0.228
1.238HisLeu: 1.238 ± 0.304
0.656HisMet: 0.656 ± 0.275
0.656HisAsn: 0.656 ± 0.217
0.583HisPro: 0.583 ± 0.204
0.437HisGln: 0.437 ± 0.216
1.384HisArg: 1.384 ± 0.384
0.583HisSer: 0.583 ± 0.274
1.166HisThr: 1.166 ± 0.241
1.02HisVal: 1.02 ± 0.314
0.146HisTrp: 0.146 ± 0.129
0.728HisTyr: 0.728 ± 0.196
0.0HisXaa: 0.0 ± 0.0
Ile
3.788IleAla: 3.788 ± 0.676
0.219IleCys: 0.219 ± 0.12
3.278IleAsp: 3.278 ± 0.615
3.205IleGlu: 3.205 ± 0.442
1.166IlePhe: 1.166 ± 0.269
2.914IleGly: 2.914 ± 0.46
1.166IleHis: 1.166 ± 0.287
2.477IleIle: 2.477 ± 0.494
2.258IleLys: 2.258 ± 0.477
3.934IleLeu: 3.934 ± 0.737
0.801IleMet: 0.801 ± 0.207
2.55IleAsn: 2.55 ± 0.393
2.623IlePro: 2.623 ± 0.458
2.623IleGln: 2.623 ± 0.403
3.351IleArg: 3.351 ± 0.389
2.768IleSer: 2.768 ± 0.46
3.715IleThr: 3.715 ± 0.456
3.642IleVal: 3.642 ± 0.533
1.166IleTrp: 1.166 ± 0.331
1.748IleTyr: 1.748 ± 0.35
0.0IleXaa: 0.0 ± 0.0
Lys
3.424LysAla: 3.424 ± 0.449
0.0LysCys: 0.0 ± 0.0
2.404LysAsp: 2.404 ± 0.404
3.715LysGlu: 3.715 ± 0.455
1.603LysPhe: 1.603 ± 0.356
4.152LysGly: 4.152 ± 0.629
1.238LysHis: 1.238 ± 0.287
1.748LysIle: 1.748 ± 0.511
2.768LysLys: 2.768 ± 0.697
4.954LysLeu: 4.954 ± 0.669
1.02LysMet: 1.02 ± 0.354
1.967LysAsn: 1.967 ± 0.439
2.04LysPro: 2.04 ± 0.569
1.894LysGln: 1.894 ± 0.351
3.06LysArg: 3.06 ± 0.433
2.623LysSer: 2.623 ± 0.519
3.57LysThr: 3.57 ± 0.634
3.715LysVal: 3.715 ± 0.47
0.947LysTrp: 0.947 ± 0.212
2.404LysTyr: 2.404 ± 0.486
0.0LysXaa: 0.0 ± 0.0
Leu
8.232LeuAla: 8.232 ± 1.078
0.219LeuCys: 0.219 ± 0.129
6.775LeuAsp: 6.775 ± 0.648
6.629LeuGlu: 6.629 ± 0.825
3.133LeuPhe: 3.133 ± 0.53
5.828LeuGly: 5.828 ± 0.45
1.676LeuHis: 1.676 ± 0.52
3.715LeuIle: 3.715 ± 0.574
5.027LeuLys: 5.027 ± 0.512
8.013LeuLeu: 8.013 ± 0.94
1.894LeuMet: 1.894 ± 0.278
5.318LeuAsn: 5.318 ± 0.666
6.046LeuPro: 6.046 ± 1.176
4.371LeuGln: 4.371 ± 0.639
5.027LeuArg: 5.027 ± 0.581
7.212LeuSer: 7.212 ± 0.656
6.338LeuThr: 6.338 ± 0.92
5.464LeuVal: 5.464 ± 0.653
0.583LeuTrp: 0.583 ± 0.182
3.715LeuTyr: 3.715 ± 0.607
0.0LeuXaa: 0.0 ± 0.0
Met
1.967MetAla: 1.967 ± 0.378
0.073MetCys: 0.073 ± 0.085
1.457MetAsp: 1.457 ± 0.319
1.02MetGlu: 1.02 ± 0.228
1.093MetPhe: 1.093 ± 0.316
1.093MetGly: 1.093 ± 0.349
0.073MetHis: 0.073 ± 0.068
1.311MetIle: 1.311 ± 0.315
1.238MetLys: 1.238 ± 0.296
2.258MetLeu: 2.258 ± 0.436
0.583MetMet: 0.583 ± 0.195
1.384MetAsn: 1.384 ± 0.284
1.53MetPro: 1.53 ± 0.328
0.947MetGln: 0.947 ± 0.354
1.603MetArg: 1.603 ± 0.293
2.331MetSer: 2.331 ± 0.568
1.967MetThr: 1.967 ± 0.366
0.656MetVal: 0.656 ± 0.23
0.437MetTrp: 0.437 ± 0.185
1.238MetTyr: 1.238 ± 0.332
0.0MetXaa: 0.0 ± 0.0
Asn
4.08AsnAla: 4.08 ± 0.531
0.437AsnCys: 0.437 ± 0.215
3.57AsnAsp: 3.57 ± 0.375
3.642AsnGlu: 3.642 ± 0.585
1.603AsnPhe: 1.603 ± 0.492
4.152AsnGly: 4.152 ± 0.736
0.801AsnHis: 0.801 ± 0.229
3.57AsnIle: 3.57 ± 0.491
2.695AsnLys: 2.695 ± 0.461
4.589AsnLeu: 4.589 ± 0.624
0.947AsnMet: 0.947 ± 0.225
3.424AsnAsn: 3.424 ± 0.649
3.278AsnPro: 3.278 ± 0.582
2.841AsnGln: 2.841 ± 0.469
2.841AsnArg: 2.841 ± 0.332
3.715AsnSer: 3.715 ± 0.652
3.861AsnThr: 3.861 ± 0.615
2.914AsnVal: 2.914 ± 0.609
0.51AsnTrp: 0.51 ± 0.231
1.603AsnTyr: 1.603 ± 0.422
0.0AsnXaa: 0.0 ± 0.0
Pro
2.55ProAla: 2.55 ± 0.492
0.219ProCys: 0.219 ± 0.113
2.55ProAsp: 2.55 ± 0.527
3.424ProGlu: 3.424 ± 0.736
1.748ProPhe: 1.748 ± 0.313
2.113ProGly: 2.113 ± 0.441
0.656ProHis: 0.656 ± 0.214
1.748ProIle: 1.748 ± 0.337
1.748ProLys: 1.748 ± 0.321
4.007ProLeu: 4.007 ± 0.879
1.457ProMet: 1.457 ± 0.329
2.477ProAsn: 2.477 ± 0.512
1.166ProPro: 1.166 ± 0.353
1.821ProGln: 1.821 ± 0.358
1.748ProArg: 1.748 ± 0.46
2.258ProSer: 2.258 ± 0.477
4.007ProThr: 4.007 ± 0.869
3.861ProVal: 3.861 ± 0.622
0.146ProTrp: 0.146 ± 0.118
1.894ProTyr: 1.894 ± 0.313
0.0ProXaa: 0.0 ± 0.0
Gln
4.444GlnAla: 4.444 ± 0.696
0.0GlnCys: 0.0 ± 0.0
2.04GlnAsp: 2.04 ± 0.534
3.642GlnGlu: 3.642 ± 0.545
1.603GlnPhe: 1.603 ± 0.303
2.914GlnGly: 2.914 ± 0.431
0.583GlnHis: 0.583 ± 0.23
1.748GlnIle: 1.748 ± 0.305
1.967GlnLys: 1.967 ± 0.408
3.788GlnLeu: 3.788 ± 0.539
1.238GlnMet: 1.238 ± 0.331
2.623GlnAsn: 2.623 ± 0.41
2.185GlnPro: 2.185 ± 0.527
2.914GlnGln: 2.914 ± 0.563
2.987GlnArg: 2.987 ± 0.62
2.841GlnSer: 2.841 ± 0.47
2.55GlnThr: 2.55 ± 0.634
2.623GlnVal: 2.623 ± 0.445
0.728GlnTrp: 0.728 ± 0.206
1.967GlnTyr: 1.967 ± 0.326
0.0GlnXaa: 0.0 ± 0.0
Arg
4.371ArgAla: 4.371 ± 0.45
0.0ArgCys: 0.0 ± 0.0
2.987ArgAsp: 2.987 ± 0.466
3.642ArgGlu: 3.642 ± 0.568
2.55ArgPhe: 2.55 ± 0.554
3.133ArgGly: 3.133 ± 0.521
1.093ArgHis: 1.093 ± 0.291
2.185ArgIle: 2.185 ± 0.479
2.768ArgLys: 2.768 ± 0.441
6.046ArgLeu: 6.046 ± 0.754
1.384ArgMet: 1.384 ± 0.353
2.258ArgAsn: 2.258 ± 0.466
1.676ArgPro: 1.676 ± 0.342
3.934ArgGln: 3.934 ± 0.614
4.007ArgArg: 4.007 ± 0.656
2.695ArgSer: 2.695 ± 0.441
3.934ArgThr: 3.934 ± 0.497
4.735ArgVal: 4.735 ± 0.451
0.656ArgTrp: 0.656 ± 0.205
2.987ArgTyr: 2.987 ± 0.425
0.0ArgXaa: 0.0 ± 0.0
Ser
5.537SerAla: 5.537 ± 0.658
0.291SerCys: 0.291 ± 0.144
3.497SerAsp: 3.497 ± 0.558
2.914SerGlu: 2.914 ± 0.628
2.404SerPhe: 2.404 ± 0.519
4.662SerGly: 4.662 ± 0.647
1.02SerHis: 1.02 ± 0.36
3.424SerIle: 3.424 ± 0.597
3.278SerLys: 3.278 ± 0.411
6.119SerLeu: 6.119 ± 0.73
1.166SerMet: 1.166 ± 0.269
3.715SerAsn: 3.715 ± 0.49
3.205SerPro: 3.205 ± 0.684
2.841SerGln: 2.841 ± 0.484
4.225SerArg: 4.225 ± 0.454
4.881SerSer: 4.881 ± 0.931
4.881SerThr: 4.881 ± 0.572
4.371SerVal: 4.371 ± 0.597
1.311SerTrp: 1.311 ± 0.305
2.258SerTyr: 2.258 ± 0.454
0.0SerXaa: 0.0 ± 0.0
Thr
4.517ThrAla: 4.517 ± 0.552
0.291ThrCys: 0.291 ± 0.148
4.444ThrAsp: 4.444 ± 0.689
4.298ThrGlu: 4.298 ± 0.783
2.331ThrPhe: 2.331 ± 0.508
5.755ThrGly: 5.755 ± 0.713
1.384ThrHis: 1.384 ± 0.25
3.205ThrIle: 3.205 ± 0.422
2.477ThrLys: 2.477 ± 0.392
7.285ThrLeu: 7.285 ± 0.895
1.311ThrMet: 1.311 ± 0.278
4.298ThrAsn: 4.298 ± 0.672
3.57ThrPro: 3.57 ± 0.493
3.133ThrGln: 3.133 ± 0.496
3.715ThrArg: 3.715 ± 0.529
4.225ThrSer: 4.225 ± 0.711
4.735ThrThr: 4.735 ± 0.908
6.119ThrVal: 6.119 ± 0.647
0.656ThrTrp: 0.656 ± 0.213
2.113ThrTyr: 2.113 ± 0.473
0.0ThrXaa: 0.0 ± 0.0
Val
5.099ValAla: 5.099 ± 0.723
0.51ValCys: 0.51 ± 0.204
3.934ValAsp: 3.934 ± 0.66
4.225ValGlu: 4.225 ± 0.494
2.841ValPhe: 2.841 ± 0.522
3.788ValGly: 3.788 ± 0.577
1.311ValHis: 1.311 ± 0.265
3.715ValIle: 3.715 ± 0.598
3.351ValLys: 3.351 ± 0.567
6.484ValLeu: 6.484 ± 0.808
2.113ValMet: 2.113 ± 0.378
4.735ValAsn: 4.735 ± 0.767
3.278ValPro: 3.278 ± 0.549
2.477ValGln: 2.477 ± 0.547
4.735ValArg: 4.735 ± 0.457
4.662ValSer: 4.662 ± 0.62
5.464ValThr: 5.464 ± 0.826
4.444ValVal: 4.444 ± 0.593
0.583ValTrp: 0.583 ± 0.231
2.841ValTyr: 2.841 ± 0.77
0.0ValXaa: 0.0 ± 0.0
Trp
0.437TrpAla: 0.437 ± 0.131
0.073TrpCys: 0.073 ± 0.074
0.437TrpAsp: 0.437 ± 0.188
1.02TrpGlu: 1.02 ± 0.328
0.51TrpPhe: 0.51 ± 0.225
0.801TrpGly: 0.801 ± 0.214
0.291TrpHis: 0.291 ± 0.156
0.146TrpIle: 0.146 ± 0.09
0.874TrpLys: 0.874 ± 0.255
1.384TrpLeu: 1.384 ± 0.312
0.437TrpMet: 0.437 ± 0.174
0.51TrpAsn: 0.51 ± 0.218
0.0TrpPro: 0.0 ± 0.0
0.874TrpGln: 0.874 ± 0.24
0.947TrpArg: 0.947 ± 0.24
0.583TrpSer: 0.583 ± 0.201
0.801TrpThr: 0.801 ± 0.261
0.728TrpVal: 0.728 ± 0.193
0.291TrpTrp: 0.291 ± 0.139
0.364TrpTyr: 0.364 ± 0.172
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.424TyrAla: 3.424 ± 0.455
0.364TyrCys: 0.364 ± 0.19
2.841TyrAsp: 2.841 ± 0.386
2.768TyrGlu: 2.768 ± 0.513
0.947TyrPhe: 0.947 ± 0.281
3.351TyrGly: 3.351 ± 0.543
0.728TyrHis: 0.728 ± 0.191
1.311TyrIle: 1.311 ± 0.332
2.623TyrLys: 2.623 ± 0.71
4.225TyrLeu: 4.225 ± 0.593
1.311TyrMet: 1.311 ± 0.347
1.676TyrAsn: 1.676 ± 0.406
1.02TyrPro: 1.02 ± 0.249
1.384TyrGln: 1.384 ± 0.271
2.113TyrArg: 2.113 ± 0.418
2.331TyrSer: 2.331 ± 0.294
2.477TyrThr: 2.477 ± 0.566
3.861TyrVal: 3.861 ± 0.71
0.291TyrTrp: 0.291 ± 0.17
1.238TyrTyr: 1.238 ± 0.391
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 55 proteins (13728 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski