Amino acid dipepetide frequency for Rottboellia yellow mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.586AlaAla: 8.586 ± 1.926
1.01AlaCys: 1.01 ± 0.883
6.566AlaAsp: 6.566 ± 1.522
6.566AlaGlu: 6.566 ± 1.121
1.515AlaPhe: 1.515 ± 1.822
7.576AlaGly: 7.576 ± 2.698
1.01AlaHis: 1.01 ± 0.758
1.01AlaIle: 1.01 ± 0.349
4.545AlaLys: 4.545 ± 1.457
6.061AlaLeu: 6.061 ± 2.446
0.505AlaMet: 0.505 ± 0.305
1.01AlaAsn: 1.01 ± 0.349
2.02AlaPro: 2.02 ± 0.779
2.525AlaGln: 2.525 ± 0.676
5.051AlaArg: 5.051 ± 0.95
10.101AlaSer: 10.101 ± 2.116
4.04AlaThr: 4.04 ± 3.223
5.051AlaVal: 5.051 ± 0.647
3.535AlaTrp: 3.535 ± 0.954
4.04AlaTyr: 4.04 ± 0.724
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.505CysCys: 0.505 ± 0.761
0.505CysAsp: 0.505 ± 0.305
3.03CysGlu: 3.03 ± 2.323
0.505CysPhe: 0.505 ± 0.305
2.02CysGly: 2.02 ± 1.484
1.01CysHis: 1.01 ± 0.349
1.01CysIle: 1.01 ± 0.349
1.01CysLys: 1.01 ± 0.774
2.02CysLeu: 2.02 ± 0.73
1.01CysMet: 1.01 ± 0.585
0.0CysAsn: 0.0 ± 0.0
1.01CysPro: 1.01 ± 0.349
0.505CysGln: 0.505 ± 0.441
0.0CysArg: 0.0 ± 0.0
3.03CysSer: 3.03 ± 1.004
0.505CysThr: 0.505 ± 0.305
1.01CysVal: 1.01 ± 0.758
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.556AspAla: 5.556 ± 1.518
0.505AspCys: 0.505 ± 0.305
4.04AspAsp: 4.04 ± 0.878
1.01AspGlu: 1.01 ± 1.222
1.01AspPhe: 1.01 ± 0.774
2.02AspGly: 2.02 ± 0.73
1.01AspHis: 1.01 ± 0.758
3.03AspIle: 3.03 ± 0.557
1.01AspLys: 1.01 ± 0.609
3.03AspLeu: 3.03 ± 1.047
3.03AspMet: 3.03 ± 0.681
1.01AspAsn: 1.01 ± 1.522
4.04AspPro: 4.04 ± 1.172
3.535AspGln: 3.535 ± 0.663
3.03AspArg: 3.03 ± 1.383
6.061AspSer: 6.061 ± 2.679
0.505AspThr: 0.505 ± 0.761
2.525AspVal: 2.525 ± 0.718
1.01AspTrp: 1.01 ± 0.609
1.515AspTyr: 1.515 ± 1.573
0.0AspXaa: 0.0 ± 0.0
Glu
10.101GluAla: 10.101 ± 1.804
1.01GluCys: 1.01 ± 0.349
5.051GluAsp: 5.051 ± 1.437
8.586GluGlu: 8.586 ± 3.407
2.525GluPhe: 2.525 ± 2.595
5.556GluGly: 5.556 ± 1.345
0.0GluHis: 0.0 ± 0.0
6.566GluIle: 6.566 ± 3.505
3.03GluLys: 3.03 ± 0.968
3.535GluLeu: 3.535 ± 1.628
2.02GluMet: 2.02 ± 0.73
1.515GluAsn: 1.515 ± 0.735
5.556GluPro: 5.556 ± 1.027
2.02GluGln: 2.02 ± 0.864
4.545GluArg: 4.545 ± 2.109
7.576GluSer: 7.576 ± 1.981
4.545GluThr: 4.545 ± 1.457
4.545GluVal: 4.545 ± 1.43
2.02GluTrp: 2.02 ± 0.452
4.04GluTyr: 4.04 ± 1.26
0.0GluXaa: 0.0 ± 0.0
Phe
2.525PheAla: 2.525 ± 0.605
1.515PheCys: 1.515 ± 0.869
1.515PheAsp: 1.515 ± 0.837
1.01PheGlu: 1.01 ± 1.522
0.505PhePhe: 0.505 ± 0.761
2.02PheGly: 2.02 ± 0.842
2.02PheHis: 2.02 ± 0.698
0.505PheIle: 0.505 ± 0.662
0.0PheLys: 0.0 ± 0.0
3.03PheLeu: 3.03 ± 0.916
0.0PheMet: 0.0 ± 0.0
1.01PheAsn: 1.01 ± 0.585
0.505PhePro: 0.505 ± 0.305
1.515PheGln: 1.515 ± 0.529
3.535PheArg: 3.535 ± 1.811
4.545PheSer: 4.545 ± 1.316
2.525PheThr: 2.525 ± 0.676
1.01PheVal: 1.01 ± 0.609
1.01PheTrp: 1.01 ± 0.349
0.505PheTyr: 0.505 ± 0.827
0.0PheXaa: 0.0 ± 0.0
Gly
6.061GlyAla: 6.061 ± 1.458
1.01GlyCys: 1.01 ± 0.349
2.525GlyAsp: 2.525 ± 0.73
6.566GlyGlu: 6.566 ± 1.077
4.04GlyPhe: 4.04 ± 1.26
3.535GlyGly: 3.535 ± 0.915
2.02GlyHis: 2.02 ± 0.643
2.02GlyIle: 2.02 ± 0.833
3.03GlyLys: 3.03 ± 0.901
5.556GlyLeu: 5.556 ± 1.497
3.03GlyMet: 3.03 ± 0.968
0.505GlyAsn: 0.505 ± 0.662
2.525GlyPro: 2.525 ± 1.736
1.01GlyGln: 1.01 ± 0.349
8.081GlyArg: 8.081 ± 1.273
9.091GlySer: 9.091 ± 2.088
4.545GlyThr: 4.545 ± 2.153
7.071GlyVal: 7.071 ± 1.917
1.01GlyTrp: 1.01 ± 0.349
2.02GlyTyr: 2.02 ± 0.73
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.01HisCys: 1.01 ± 0.349
0.505HisAsp: 0.505 ± 0.827
2.525HisGlu: 2.525 ± 0.813
0.0HisPhe: 0.0 ± 0.0
0.505HisGly: 0.505 ± 0.305
1.515HisHis: 1.515 ± 0.667
0.0HisIle: 0.0 ± 0.0
0.505HisLys: 0.505 ± 0.305
0.505HisLeu: 0.505 ± 0.305
0.505HisMet: 0.505 ± 0.411
0.0HisAsn: 0.0 ± 0.0
1.01HisPro: 1.01 ± 0.774
1.01HisGln: 1.01 ± 0.758
2.02HisArg: 2.02 ± 0.678
1.515HisSer: 1.515 ± 0.692
0.0HisThr: 0.0 ± 0.0
4.04HisVal: 4.04 ± 1.396
0.505HisTrp: 0.505 ± 0.305
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.515IleAla: 1.515 ± 0.484
0.505IleCys: 0.505 ± 0.662
2.02IleAsp: 2.02 ± 0.643
2.525IleGlu: 2.525 ± 1.614
0.0IlePhe: 0.0 ± 0.0
3.03IleGly: 3.03 ± 0.968
1.515IleHis: 1.515 ± 0.484
2.02IleIle: 2.02 ± 0.698
4.04IleLys: 4.04 ± 0.968
1.01IleLeu: 1.01 ± 0.349
0.505IleMet: 0.505 ± 0.994
0.0IleAsn: 0.0 ± 0.0
0.0IlePro: 0.0 ± 0.0
5.051IleGln: 5.051 ± 1.745
3.03IleArg: 3.03 ± 0.781
6.061IleSer: 6.061 ± 1.293
1.01IleThr: 1.01 ± 0.349
1.01IleVal: 1.01 ± 1.093
0.505IleTrp: 0.505 ± 0.662
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.02LysAla: 2.02 ± 0.452
1.01LysCys: 1.01 ± 0.774
3.03LysAsp: 3.03 ± 0.968
4.04LysGlu: 4.04 ± 1.272
2.525LysPhe: 2.525 ± 0.73
4.545LysGly: 4.545 ± 1.097
0.0LysHis: 0.0 ± 0.0
2.02LysIle: 2.02 ± 0.73
2.02LysLys: 2.02 ± 0.698
3.03LysLeu: 3.03 ± 0.968
0.505LysMet: 0.505 ± 0.441
0.0LysAsn: 0.0 ± 0.0
2.02LysPro: 2.02 ± 0.678
3.03LysGln: 3.03 ± 0.958
4.545LysArg: 4.545 ± 0.9
4.545LysSer: 4.545 ± 0.9
1.515LysThr: 1.515 ± 0.96
2.525LysVal: 2.525 ± 0.718
2.02LysTrp: 2.02 ± 0.842
2.525LysTyr: 2.525 ± 0.561
0.0LysXaa: 0.0 ± 0.0
Leu
7.071LeuAla: 7.071 ± 1.324
1.01LeuCys: 1.01 ± 0.609
2.525LeuAsp: 2.525 ± 0.813
7.071LeuGlu: 7.071 ± 1.537
2.525LeuPhe: 2.525 ± 1.601
5.556LeuGly: 5.556 ± 1.193
0.0LeuHis: 0.0 ± 0.0
6.061LeuIle: 6.061 ± 1.968
3.03LeuLys: 3.03 ± 0.725
5.556LeuLeu: 5.556 ± 0.896
3.535LeuMet: 3.535 ± 0.987
4.04LeuAsn: 4.04 ± 1.26
4.545LeuPro: 4.545 ± 0.788
1.01LeuGln: 1.01 ± 0.609
4.04LeuArg: 4.04 ± 0.982
10.101LeuSer: 10.101 ± 1.477
3.03LeuThr: 3.03 ± 0.768
5.556LeuVal: 5.556 ± 1.799
1.01LeuTrp: 1.01 ± 0.349
4.04LeuTyr: 4.04 ± 1.236
0.0LeuXaa: 0.0 ± 0.0
Met
1.515MetAla: 1.515 ± 0.658
0.0MetCys: 0.0 ± 0.0
0.505MetAsp: 0.505 ± 0.761
2.02MetGlu: 2.02 ± 0.452
0.0MetPhe: 0.0 ± 0.0
2.525MetGly: 2.525 ± 1.008
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.515MetLys: 1.515 ± 0.484
1.515MetLeu: 1.515 ± 0.484
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.505MetPro: 0.505 ± 0.305
1.01MetGln: 1.01 ± 0.735
1.515MetArg: 1.515 ± 0.484
2.525MetSer: 2.525 ± 0.561
1.01MetThr: 1.01 ± 1.093
1.515MetVal: 1.515 ± 0.529
1.01MetTrp: 1.01 ± 0.349
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.505AsnAla: 0.505 ± 0.662
1.01AsnCys: 1.01 ± 0.854
1.515AsnAsp: 1.515 ± 0.484
1.515AsnGlu: 1.515 ± 0.529
2.525AsnPhe: 2.525 ± 1.025
2.02AsnGly: 2.02 ± 0.452
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
1.01AsnLys: 1.01 ± 0.349
2.02AsnLeu: 2.02 ± 0.452
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.01AsnPro: 1.01 ± 0.785
0.0AsnGln: 0.0 ± 0.0
4.04AsnArg: 4.04 ± 0.635
3.535AsnSer: 3.535 ± 1.039
0.505AsnThr: 0.505 ± 0.305
1.515AsnVal: 1.515 ± 0.529
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
5.556ProAla: 5.556 ± 2.29
1.01ProCys: 1.01 ± 0.609
1.01ProAsp: 1.01 ± 0.758
2.525ProGlu: 2.525 ± 0.787
1.515ProPhe: 1.515 ± 0.529
6.566ProGly: 6.566 ± 1.708
1.01ProHis: 1.01 ± 0.609
1.01ProIle: 1.01 ± 0.585
0.0ProLys: 0.0 ± 0.0
3.535ProLeu: 3.535 ± 1.048
1.01ProMet: 1.01 ± 0.349
2.02ProAsn: 2.02 ± 0.452
2.02ProPro: 2.02 ± 0.698
3.03ProGln: 3.03 ± 0.968
2.525ProArg: 2.525 ± 0.813
4.04ProSer: 4.04 ± 1.285
3.03ProThr: 3.03 ± 0.557
4.545ProVal: 4.545 ± 1.652
0.505ProTrp: 0.505 ± 0.662
1.515ProTyr: 1.515 ± 0.735
0.0ProXaa: 0.0 ± 0.0
Gln
5.051GlnAla: 5.051 ± 1.07
0.0GlnCys: 0.0 ± 0.0
1.515GlnAsp: 1.515 ± 0.484
4.04GlnGlu: 4.04 ± 1.26
2.525GlnPhe: 2.525 ± 1.063
2.525GlnGly: 2.525 ± 0.73
0.505GlnHis: 0.505 ± 0.305
0.0GlnIle: 0.0 ± 0.0
1.515GlnLys: 1.515 ± 0.735
1.01GlnLeu: 1.01 ± 0.609
0.0GlnMet: 0.0 ± 0.0
2.525GlnAsn: 2.525 ± 0.787
3.03GlnPro: 3.03 ± 0.557
0.0GlnGln: 0.0 ± 0.0
2.525GlnArg: 2.525 ± 0.745
2.525GlnSer: 2.525 ± 1.245
1.515GlnThr: 1.515 ± 1.607
1.01GlnVal: 1.01 ± 0.854
0.505GlnTrp: 0.505 ± 0.305
1.01GlnTyr: 1.01 ± 1.093
0.0GlnXaa: 0.0 ± 0.0
Arg
5.051ArgAla: 5.051 ± 2.243
0.505ArgCys: 0.505 ± 0.305
3.535ArgAsp: 3.535 ± 2.095
6.566ArgGlu: 6.566 ± 2.044
3.535ArgPhe: 3.535 ± 1.72
6.061ArgGly: 6.061 ± 1.122
0.0ArgHis: 0.0 ± 0.0
3.03ArgIle: 3.03 ± 1.103
1.515ArgLys: 1.515 ± 0.529
9.596ArgLeu: 9.596 ± 1.254
1.01ArgMet: 1.01 ± 0.585
1.515ArgAsn: 1.515 ± 0.658
0.505ArgPro: 0.505 ± 0.305
0.505ArgGln: 0.505 ± 0.305
5.556ArgArg: 5.556 ± 3.167
6.566ArgSer: 6.566 ± 1.855
5.051ArgThr: 5.051 ± 1.614
7.576ArgVal: 7.576 ± 1.618
1.515ArgTrp: 1.515 ± 0.484
2.02ArgTyr: 2.02 ± 0.73
0.0ArgXaa: 0.0 ± 0.0
Ser
8.081SerAla: 8.081 ± 3.166
3.535SerCys: 3.535 ± 3.027
3.535SerAsp: 3.535 ± 1.3
7.576SerGlu: 7.576 ± 1.737
3.03SerPhe: 3.03 ± 0.557
9.091SerGly: 9.091 ± 1.596
2.02SerHis: 2.02 ± 0.678
3.03SerIle: 3.03 ± 0.958
6.566SerLys: 6.566 ± 0.636
10.606SerLeu: 10.606 ± 1.197
1.01SerMet: 1.01 ± 0.515
3.03SerAsn: 3.03 ± 0.557
8.586SerPro: 8.586 ± 1.425
2.02SerGln: 2.02 ± 0.643
9.091SerArg: 9.091 ± 0.687
10.606SerSer: 10.606 ± 1.293
6.061SerThr: 6.061 ± 2.477
8.081SerVal: 8.081 ± 1.273
3.03SerTrp: 3.03 ± 0.557
1.515SerTyr: 1.515 ± 0.96
0.0SerXaa: 0.0 ± 0.0
Thr
2.525ThrAla: 2.525 ± 2.668
1.515ThrCys: 1.515 ± 0.692
0.505ThrAsp: 0.505 ± 0.305
3.535ThrGlu: 3.535 ± 1.54
0.505ThrPhe: 0.505 ± 0.662
2.02ThrGly: 2.02 ± 0.452
1.01ThrHis: 1.01 ± 0.349
1.515ThrIle: 1.515 ± 0.529
4.04ThrLys: 4.04 ± 0.904
5.556ThrLeu: 5.556 ± 1.012
0.505ThrMet: 0.505 ± 0.662
2.02ThrAsn: 2.02 ± 1.862
3.535ThrPro: 3.535 ± 1.257
1.01ThrGln: 1.01 ± 0.349
1.515ThrArg: 1.515 ± 1.607
6.061ThrSer: 6.061 ± 2.055
6.566ThrThr: 6.566 ± 0.686
2.02ThrVal: 2.02 ± 1.146
1.01ThrTrp: 1.01 ± 0.585
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.03ValAla: 3.03 ± 0.557
1.01ValCys: 1.01 ± 0.349
4.545ValAsp: 4.545 ± 1.883
8.586ValGlu: 8.586 ± 1.598
2.02ValPhe: 2.02 ± 0.73
4.04ValGly: 4.04 ± 0.812
3.03ValHis: 3.03 ± 1.383
2.02ValIle: 2.02 ± 0.698
5.051ValLys: 5.051 ± 0.719
5.051ValLeu: 5.051 ± 1.574
0.0ValMet: 0.0 ± 0.0
1.01ValAsn: 1.01 ± 1.323
3.03ValPro: 3.03 ± 1.023
2.525ValGln: 2.525 ± 1.025
3.535ValArg: 3.535 ± 2.152
6.566ValSer: 6.566 ± 0.686
1.01ValThr: 1.01 ± 1.323
10.101ValVal: 10.101 ± 2.23
3.03ValTrp: 3.03 ± 0.968
4.04ValTyr: 4.04 ± 0.878
0.0ValXaa: 0.0 ± 0.0
Trp
2.02TrpAla: 2.02 ± 0.842
0.505TrpCys: 0.505 ± 0.305
2.02TrpAsp: 2.02 ± 0.73
4.04TrpGlu: 4.04 ± 0.869
0.0TrpPhe: 0.0 ± 0.0
0.505TrpGly: 0.505 ± 0.662
0.0TrpHis: 0.0 ± 0.0
1.01TrpIle: 1.01 ± 0.349
1.515TrpLys: 1.515 ± 0.484
3.535TrpLeu: 3.535 ± 0.834
0.0TrpMet: 0.0 ± 0.0
1.01TrpAsn: 1.01 ± 0.349
2.02TrpPro: 2.02 ± 0.73
0.0TrpGln: 0.0 ± 0.0
1.01TrpArg: 1.01 ± 0.349
3.03TrpSer: 3.03 ± 0.557
0.0TrpThr: 0.0 ± 0.0
0.505TrpVal: 0.505 ± 0.761
0.0TrpTrp: 0.0 ± 0.0
0.505TrpTyr: 0.505 ± 0.662
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.556TyrAla: 5.556 ± 1.193
0.505TyrCys: 0.505 ± 0.305
1.515TyrAsp: 1.515 ± 1.822
1.01TyrGlu: 1.01 ± 0.349
0.0TyrPhe: 0.0 ± 0.0
3.535TyrGly: 3.535 ± 0.781
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
2.525TyrLys: 2.525 ± 0.718
5.556TyrLeu: 5.556 ± 0.405
0.0TyrMet: 0.0 ± 0.0
0.505TyrAsn: 0.505 ± 0.827
0.505TyrPro: 0.505 ± 0.305
2.02TyrGln: 2.02 ± 0.993
2.02TyrArg: 2.02 ± 1.171
2.02TyrSer: 2.02 ± 0.864
0.0TyrThr: 0.0 ± 0.0
2.02TyrVal: 2.02 ± 0.842
0.0TyrTrp: 0.0 ± 0.0
1.515TyrTyr: 1.515 ± 0.692
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1981 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski