Amino acid dipepetide frequency for Rinderpest morbillivirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.252AlaAla: 4.252 ± 0.849
0.85AlaCys: 0.85 ± 0.365
4.039AlaAsp: 4.039 ± 0.929
3.401AlaGlu: 3.401 ± 0.742
1.701AlaPhe: 1.701 ± 0.39
4.464AlaGly: 4.464 ± 1.723
1.063AlaHis: 1.063 ± 0.464
4.039AlaIle: 4.039 ± 0.929
2.976AlaLys: 2.976 ± 0.557
7.866AlaLeu: 7.866 ± 1.065
1.276AlaMet: 1.276 ± 0.389
1.276AlaAsn: 1.276 ± 0.601
1.488AlaPro: 1.488 ± 0.423
1.913AlaGln: 1.913 ± 0.433
3.827AlaArg: 3.827 ± 1.282
4.464AlaSer: 4.464 ± 2.096
4.252AlaThr: 4.252 ± 0.695
4.677AlaVal: 4.677 ± 1.268
0.425AlaTrp: 0.425 ± 0.306
2.764AlaTyr: 2.764 ± 0.353
0.0AlaXaa: 0.0 ± 0.0
Cys
1.063CysAla: 1.063 ± 0.741
0.638CysCys: 0.638 ± 0.51
0.85CysAsp: 0.85 ± 0.241
0.425CysGlu: 0.425 ± 0.241
1.488CysPhe: 1.488 ± 0.309
0.638CysGly: 0.638 ± 0.368
0.213CysHis: 0.213 ± 0.261
1.063CysIle: 1.063 ± 0.277
1.063CysLys: 1.063 ± 0.699
1.063CysLeu: 1.063 ± 0.339
0.213CysMet: 0.213 ± 0.261
1.276CysAsn: 1.276 ± 0.571
0.638CysPro: 0.638 ± 0.258
0.638CysGln: 0.638 ± 0.368
0.638CysArg: 0.638 ± 0.523
1.488CysSer: 1.488 ± 0.309
0.85CysThr: 0.85 ± 0.221
1.063CysVal: 1.063 ± 0.613
0.0CysTrp: 0.0 ± 0.0
1.488CysTyr: 1.488 ± 0.496
0.0CysXaa: 0.0 ± 0.0
Asp
1.063AspAla: 1.063 ± 0.731
1.063AspCys: 1.063 ± 0.339
4.252AspAsp: 4.252 ± 0.898
2.976AspGlu: 2.976 ± 0.541
0.85AspPhe: 0.85 ± 0.323
1.701AspGly: 1.701 ± 0.468
1.276AspHis: 1.276 ± 0.472
5.527AspIle: 5.527 ± 0.662
3.827AspLys: 3.827 ± 0.963
6.59AspLeu: 6.59 ± 0.653
0.425AspMet: 0.425 ± 0.245
2.976AspAsn: 2.976 ± 0.824
5.527AspPro: 5.527 ± 0.65
1.913AspGln: 1.913 ± 0.651
4.252AspArg: 4.252 ± 0.758
5.315AspSer: 5.315 ± 0.595
3.614AspThr: 3.614 ± 1.107
2.976AspVal: 2.976 ± 0.691
0.638AspTrp: 0.638 ± 0.241
1.701AspTyr: 1.701 ± 0.226
0.0AspXaa: 0.0 ± 0.0
Glu
4.889GluAla: 4.889 ± 1.026
0.85GluCys: 0.85 ± 0.411
2.976GluAsp: 2.976 ± 1.281
2.764GluGlu: 2.764 ± 0.65
2.126GluPhe: 2.126 ± 0.483
2.551GluGly: 2.551 ± 1.048
0.85GluHis: 0.85 ± 0.365
5.527GluIle: 5.527 ± 0.989
3.614GluLys: 3.614 ± 0.663
5.74GluLeu: 5.74 ± 0.686
1.063GluMet: 1.063 ± 0.359
1.276GluAsn: 1.276 ± 0.377
1.913GluPro: 1.913 ± 0.415
1.488GluGln: 1.488 ± 0.385
1.701GluArg: 1.701 ± 0.601
3.189GluSer: 3.189 ± 1.112
4.677GluThr: 4.677 ± 1.359
3.189GluVal: 3.189 ± 0.221
0.85GluTrp: 0.85 ± 0.324
1.488GluTyr: 1.488 ± 0.685
0.0GluXaa: 0.0 ± 0.0
Phe
1.701PheAla: 1.701 ± 0.51
0.85PheCys: 0.85 ± 0.489
1.701PheAsp: 1.701 ± 0.413
1.488PheGlu: 1.488 ± 0.515
1.276PhePhe: 1.276 ± 0.736
1.913PheGly: 1.913 ± 0.307
0.85PheHis: 0.85 ± 0.229
2.338PheIle: 2.338 ± 0.517
1.913PheLys: 1.913 ± 0.609
2.976PheLeu: 2.976 ± 1.004
1.063PheMet: 1.063 ± 0.483
1.063PheAsn: 1.063 ± 0.336
0.425PhePro: 0.425 ± 0.244
0.425PheGln: 0.425 ± 0.195
3.189PheArg: 3.189 ± 0.87
1.913PheSer: 1.913 ± 0.359
1.913PheThr: 1.913 ± 0.456
2.338PheVal: 2.338 ± 0.633
1.063PheTrp: 1.063 ± 0.426
0.638PheTyr: 0.638 ± 0.318
0.0PheXaa: 0.0 ± 0.0
Gly
3.189GlyAla: 3.189 ± 0.957
0.85GlyCys: 0.85 ± 0.323
4.677GlyAsp: 4.677 ± 0.909
3.614GlyGlu: 3.614 ± 1.148
1.913GlyPhe: 1.913 ± 0.547
3.827GlyGly: 3.827 ± 0.895
1.276GlyHis: 1.276 ± 0.538
5.315GlyIle: 5.315 ± 1.352
2.764GlyLys: 2.764 ± 0.953
8.716GlyLeu: 8.716 ± 1.203
1.488GlyMet: 1.488 ± 0.644
2.764GlyAsn: 2.764 ± 0.602
3.189GlyPro: 3.189 ± 0.74
2.126GlyGln: 2.126 ± 1.01
2.976GlyArg: 2.976 ± 0.82
6.59GlySer: 6.59 ± 1.964
4.039GlyThr: 4.039 ± 1.26
4.889GlyVal: 4.889 ± 1.302
0.425GlyTrp: 0.425 ± 0.179
1.913GlyTyr: 1.913 ± 0.614
0.0GlyXaa: 0.0 ± 0.0
His
1.488HisAla: 1.488 ± 0.543
0.425HisCys: 0.425 ± 0.245
1.276HisAsp: 1.276 ± 0.362
2.126HisGlu: 2.126 ± 0.512
0.638HisPhe: 0.638 ± 0.285
0.425HisGly: 0.425 ± 0.245
1.063HisHis: 1.063 ± 0.464
1.701HisIle: 1.701 ± 0.767
0.425HisLys: 0.425 ± 0.241
2.338HisLeu: 2.338 ± 0.759
0.85HisMet: 0.85 ± 0.365
1.063HisAsn: 1.063 ± 0.251
0.638HisPro: 0.638 ± 0.368
1.701HisGln: 1.701 ± 0.613
2.338HisArg: 2.338 ± 0.754
0.85HisSer: 0.85 ± 0.322
1.063HisThr: 1.063 ± 0.517
1.276HisVal: 1.276 ± 0.4
0.213HisTrp: 0.213 ± 0.282
0.425HisTyr: 0.425 ± 0.244
0.0HisXaa: 0.0 ± 0.0
Ile
4.889IleAla: 4.889 ± 1.035
0.85IleCys: 0.85 ± 0.252
4.252IleAsp: 4.252 ± 0.23
5.102IleGlu: 5.102 ± 0.341
1.276IlePhe: 1.276 ± 0.592
4.889IleGly: 4.889 ± 0.543
1.063IleHis: 1.063 ± 0.417
4.889IleIle: 4.889 ± 0.757
5.952IleLys: 5.952 ± 0.881
8.929IleLeu: 8.929 ± 2.016
0.85IleMet: 0.85 ± 0.307
3.614IleAsn: 3.614 ± 0.572
2.976IlePro: 2.976 ± 0.653
4.039IleGln: 4.039 ± 1.184
4.677IleArg: 4.677 ± 0.747
6.59IleSer: 6.59 ± 0.771
5.74IleThr: 5.74 ± 1.218
3.827IleVal: 3.827 ± 0.713
0.213IleTrp: 0.213 ± 0.197
2.764IleTyr: 2.764 ± 0.989
0.0IleXaa: 0.0 ± 0.0
Lys
2.976LysAla: 2.976 ± 0.944
0.638LysCys: 0.638 ± 0.326
3.189LysAsp: 3.189 ± 0.376
3.401LysGlu: 3.401 ± 0.815
2.126LysPhe: 2.126 ± 0.696
3.614LysGly: 3.614 ± 0.783
1.276LysHis: 1.276 ± 0.419
4.252LysIle: 4.252 ± 1.345
3.827LysLys: 3.827 ± 1.141
6.803LysLeu: 6.803 ± 0.785
2.338LysMet: 2.338 ± 0.988
2.126LysAsn: 2.126 ± 0.529
2.338LysPro: 2.338 ± 0.989
1.913LysGln: 1.913 ± 0.397
2.338LysArg: 2.338 ± 0.759
5.952LysSer: 5.952 ± 1.435
2.338LysThr: 2.338 ± 0.592
2.551LysVal: 2.551 ± 0.547
0.0LysTrp: 0.0 ± 0.0
1.488LysTyr: 1.488 ± 0.671
0.0LysXaa: 0.0 ± 0.0
Leu
9.779LeuAla: 9.779 ± 1.717
1.488LeuCys: 1.488 ± 0.309
5.315LeuAsp: 5.315 ± 0.945
5.952LeuGlu: 5.952 ± 1.015
4.464LeuPhe: 4.464 ± 0.757
8.929LeuGly: 8.929 ± 0.956
4.039LeuHis: 4.039 ± 0.598
7.653LeuIle: 7.653 ± 1.117
8.291LeuLys: 8.291 ± 1.384
10.629LeuLeu: 10.629 ± 1.159
2.551LeuMet: 2.551 ± 0.395
4.252LeuAsn: 4.252 ± 0.706
2.338LeuPro: 2.338 ± 0.876
1.913LeuGln: 1.913 ± 0.874
5.315LeuArg: 5.315 ± 0.67
8.716LeuSer: 8.716 ± 1.074
5.74LeuThr: 5.74 ± 1.014
6.59LeuVal: 6.59 ± 0.462
1.276LeuTrp: 1.276 ± 0.262
2.764LeuTyr: 2.764 ± 0.776
0.0LeuXaa: 0.0 ± 0.0
Met
1.488MetAla: 1.488 ± 0.562
0.0MetCys: 0.0 ± 0.0
1.276MetAsp: 1.276 ± 0.293
0.213MetGlu: 0.213 ± 0.282
0.213MetPhe: 0.213 ± 0.261
2.126MetGly: 2.126 ± 0.723
0.213MetHis: 0.213 ± 0.123
2.338MetIle: 2.338 ± 0.481
0.638MetLys: 0.638 ± 0.3
2.126MetLeu: 2.126 ± 0.663
0.213MetMet: 0.213 ± 0.123
1.063MetAsn: 1.063 ± 0.283
0.85MetPro: 0.85 ± 0.324
0.213MetGln: 0.213 ± 0.123
0.85MetArg: 0.85 ± 0.491
1.913MetSer: 1.913 ± 0.504
2.126MetThr: 2.126 ± 0.442
2.126MetVal: 2.126 ± 0.644
0.213MetTrp: 0.213 ± 0.123
1.276MetTyr: 1.276 ± 0.335
0.0MetXaa: 0.0 ± 0.0
Asn
2.551AsnAla: 2.551 ± 1.033
0.85AsnCys: 0.85 ± 0.324
2.551AsnAsp: 2.551 ± 0.618
2.338AsnGlu: 2.338 ± 0.635
1.276AsnPhe: 1.276 ± 0.289
1.701AsnGly: 1.701 ± 0.621
0.85AsnHis: 0.85 ± 0.365
3.189AsnIle: 3.189 ± 0.748
1.701AsnLys: 1.701 ± 0.792
4.252AsnLeu: 4.252 ± 0.64
1.276AsnMet: 1.276 ± 0.381
0.85AsnAsn: 0.85 ± 0.31
1.701AsnPro: 1.701 ± 0.325
2.126AsnGln: 2.126 ± 0.597
1.063AsnArg: 1.063 ± 0.453
4.464AsnSer: 4.464 ± 1.016
2.126AsnThr: 2.126 ± 0.629
1.701AsnVal: 1.701 ± 0.626
0.85AsnTrp: 0.85 ± 0.365
2.126AsnTyr: 2.126 ± 0.701
0.0AsnXaa: 0.0 ± 0.0
Pro
2.551ProAla: 2.551 ± 0.998
0.425ProCys: 0.425 ± 0.402
2.976ProAsp: 2.976 ± 0.945
3.189ProGlu: 3.189 ± 0.359
0.425ProPhe: 0.425 ± 0.244
3.401ProGly: 3.401 ± 0.901
0.425ProHis: 0.425 ± 0.245
4.677ProIle: 4.677 ± 0.6
1.488ProLys: 1.488 ± 0.56
4.252ProLeu: 4.252 ± 1.464
0.85ProMet: 0.85 ± 0.324
1.913ProAsn: 1.913 ± 0.286
2.764ProPro: 2.764 ± 0.745
1.488ProGln: 1.488 ± 0.784
2.976ProArg: 2.976 ± 0.587
4.889ProSer: 4.889 ± 0.412
2.126ProThr: 2.126 ± 0.553
2.338ProVal: 2.338 ± 0.757
0.638ProTrp: 0.638 ± 0.402
2.338ProTyr: 2.338 ± 0.963
0.0ProXaa: 0.0 ± 0.0
Gln
1.913GlnAla: 1.913 ± 1.096
1.488GlnCys: 1.488 ± 0.239
1.701GlnAsp: 1.701 ± 0.561
1.488GlnGlu: 1.488 ± 0.76
0.85GlnPhe: 0.85 ± 0.463
2.338GlnGly: 2.338 ± 0.752
0.425GlnHis: 0.425 ± 0.179
2.338GlnIle: 2.338 ± 0.403
1.063GlnLys: 1.063 ± 0.471
2.976GlnLeu: 2.976 ± 0.422
0.85GlnMet: 0.85 ± 0.241
1.488GlnAsn: 1.488 ± 0.172
1.276GlnPro: 1.276 ± 0.299
2.126GlnGln: 2.126 ± 0.506
2.551GlnArg: 2.551 ± 0.689
3.827GlnSer: 3.827 ± 1.163
0.425GlnThr: 0.425 ± 0.179
3.189GlnVal: 3.189 ± 0.367
0.425GlnTrp: 0.425 ± 0.245
0.638GlnTyr: 0.638 ± 0.49
0.0GlnXaa: 0.0 ± 0.0
Arg
2.764ArgAla: 2.764 ± 0.717
0.213ArgCys: 0.213 ± 0.123
3.401ArgAsp: 3.401 ± 0.649
3.401ArgGlu: 3.401 ± 0.775
1.913ArgPhe: 1.913 ± 0.396
4.039ArgGly: 4.039 ± 0.52
1.063ArgHis: 1.063 ± 0.417
3.189ArgIle: 3.189 ± 0.636
2.551ArgLys: 2.551 ± 0.697
6.803ArgLeu: 6.803 ± 1.393
1.276ArgMet: 1.276 ± 0.2
1.701ArgAsn: 1.701 ± 0.531
3.189ArgPro: 3.189 ± 1.023
1.276ArgGln: 1.276 ± 0.252
4.252ArgArg: 4.252 ± 0.635
5.102ArgSer: 5.102 ± 0.521
2.976ArgThr: 2.976 ± 0.694
4.039ArgVal: 4.039 ± 1.183
0.213ArgTrp: 0.213 ± 0.197
2.551ArgTyr: 2.551 ± 0.713
0.0ArgXaa: 0.0 ± 0.0
Ser
5.315SerAla: 5.315 ± 0.847
1.701SerCys: 1.701 ± 0.665
5.74SerAsp: 5.74 ± 0.975
2.338SerGlu: 2.338 ± 0.58
2.338SerPhe: 2.338 ± 0.991
7.228SerGly: 7.228 ± 0.885
2.126SerHis: 2.126 ± 0.75
5.952SerIle: 5.952 ± 1.338
4.677SerLys: 4.677 ± 0.88
9.991SerLeu: 9.991 ± 0.889
1.701SerMet: 1.701 ± 0.483
4.039SerAsn: 4.039 ± 0.819
3.614SerPro: 3.614 ± 0.47
2.126SerGln: 2.126 ± 0.979
5.74SerArg: 5.74 ± 0.95
8.503SerSer: 8.503 ± 1.859
6.378SerThr: 6.378 ± 0.499
3.827SerVal: 3.827 ± 0.459
1.276SerTrp: 1.276 ± 0.592
2.551SerTyr: 2.551 ± 1.256
0.0SerXaa: 0.0 ± 0.0
Thr
4.252ThrAla: 4.252 ± 0.669
0.85ThrCys: 0.85 ± 0.453
2.976ThrAsp: 2.976 ± 0.695
2.764ThrGlu: 2.764 ± 0.32
1.701ThrPhe: 1.701 ± 0.611
5.315ThrGly: 5.315 ± 0.636
0.85ThrHis: 0.85 ± 0.489
5.315ThrIle: 5.315 ± 0.886
3.827ThrLys: 3.827 ± 0.693
4.889ThrLeu: 4.889 ± 1.127
1.063ThrMet: 1.063 ± 0.251
2.551ThrAsn: 2.551 ± 0.784
3.401ThrPro: 3.401 ± 1.263
2.338ThrGln: 2.338 ± 0.508
2.551ThrArg: 2.551 ± 0.503
4.039ThrSer: 4.039 ± 0.596
4.252ThrThr: 4.252 ± 0.705
2.976ThrVal: 2.976 ± 0.588
0.638ThrTrp: 0.638 ± 0.236
3.614ThrTyr: 3.614 ± 0.545
0.0ThrXaa: 0.0 ± 0.0
Val
2.764ValAla: 2.764 ± 0.502
1.063ValCys: 1.063 ± 0.484
2.764ValAsp: 2.764 ± 0.508
4.252ValGlu: 4.252 ± 0.903
2.126ValPhe: 2.126 ± 0.836
4.677ValGly: 4.677 ± 2.163
1.913ValHis: 1.913 ± 0.532
4.677ValIle: 4.677 ± 0.447
2.764ValLys: 2.764 ± 1.021
5.527ValLeu: 5.527 ± 0.973
0.85ValMet: 0.85 ± 0.221
2.126ValAsn: 2.126 ± 1.147
4.252ValPro: 4.252 ± 0.654
2.338ValGln: 2.338 ± 0.596
3.189ValArg: 3.189 ± 0.817
5.315ValSer: 5.315 ± 0.879
3.401ValThr: 3.401 ± 0.553
4.252ValVal: 4.252 ± 0.971
0.425ValTrp: 0.425 ± 0.522
1.701ValTyr: 1.701 ± 0.39
0.0ValXaa: 0.0 ± 0.0
Trp
1.276TrpAla: 1.276 ± 0.419
0.425TrpCys: 0.425 ± 0.522
0.425TrpAsp: 0.425 ± 0.252
0.213TrpGlu: 0.213 ± 0.261
1.063TrpPhe: 1.063 ± 0.439
1.276TrpGly: 1.276 ± 0.676
0.213TrpHis: 0.213 ± 0.123
0.425TrpIle: 0.425 ± 0.179
0.638TrpLys: 0.638 ± 0.3
0.85TrpLeu: 0.85 ± 0.292
0.0TrpMet: 0.0 ± 0.0
0.213TrpAsn: 0.213 ± 0.282
0.638TrpPro: 0.638 ± 0.285
0.213TrpGln: 0.213 ± 0.261
0.425TrpArg: 0.425 ± 0.252
0.638TrpSer: 0.638 ± 0.236
0.425TrpThr: 0.425 ± 0.245
0.638TrpVal: 0.638 ± 0.249
0.0TrpTrp: 0.0 ± 0.0
0.213TrpTyr: 0.213 ± 0.282
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.85TyrAla: 0.85 ± 0.252
1.276TyrCys: 1.276 ± 0.449
2.126TyrAsp: 2.126 ± 0.782
1.488TyrGlu: 1.488 ± 0.654
1.276TyrPhe: 1.276 ± 0.539
1.488TyrGly: 1.488 ± 0.756
1.276TyrHis: 1.276 ± 0.472
2.976TyrIle: 2.976 ± 0.55
1.488TyrLys: 1.488 ± 0.372
4.677TyrLeu: 4.677 ± 1.362
1.063TyrMet: 1.063 ± 0.317
1.913TyrAsn: 1.913 ± 0.661
2.976TyrPro: 2.976 ± 0.473
1.063TyrGln: 1.063 ± 0.339
1.063TyrArg: 1.063 ± 0.464
3.401TyrSer: 3.401 ± 0.886
1.701TyrThr: 1.701 ± 0.744
1.913TyrVal: 1.913 ± 0.614
0.425TyrTrp: 0.425 ± 0.339
1.488TyrTyr: 1.488 ± 0.624
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (4705 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski