Amino acid dipepetide frequency for Chlamydia virus CPAR39

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.782AlaAla: 0.782 ± 0.55
0.782AlaCys: 0.782 ± 0.766
2.346AlaAsp: 2.346 ± 0.761
4.691AlaGlu: 4.691 ± 2.069
6.255AlaPhe: 6.255 ± 1.987
4.691AlaGly: 4.691 ± 2.089
0.0AlaHis: 0.0 ± 0.0
1.564AlaIle: 1.564 ± 0.794
4.691AlaLys: 4.691 ± 3.274
3.127AlaLeu: 3.127 ± 1.575
2.346AlaMet: 2.346 ± 2.027
0.782AlaAsn: 0.782 ± 0.913
3.127AlaPro: 3.127 ± 1.571
5.473AlaGln: 5.473 ± 2.135
5.473AlaArg: 5.473 ± 1.948
5.473AlaSer: 5.473 ± 2.748
4.691AlaThr: 4.691 ± 1.739
4.691AlaVal: 4.691 ± 2.096
0.782AlaTrp: 0.782 ± 0.55
4.691AlaTyr: 4.691 ± 1.797
0.0AlaXaa: 0.0 ± 0.0
Cys
0.782CysAla: 0.782 ± 0.55
0.782CysCys: 0.782 ± 0.766
1.564CysAsp: 1.564 ± 0.865
0.0CysGlu: 0.0 ± 0.0
1.564CysPhe: 1.564 ± 1.531
2.346CysGly: 2.346 ± 0.842
0.0CysHis: 0.0 ± 0.0
0.782CysIle: 0.782 ± 1.596
1.564CysLys: 1.564 ± 2.252
1.564CysLeu: 1.564 ± 0.588
1.564CysMet: 1.564 ± 1.099
0.782CysAsn: 0.782 ± 0.766
0.782CysPro: 0.782 ± 1.126
0.782CysGln: 0.782 ± 0.55
1.564CysArg: 1.564 ± 1.531
0.782CysSer: 0.782 ± 0.766
0.0CysThr: 0.0 ± 0.0
1.564CysVal: 1.564 ± 0.588
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.691AspAla: 4.691 ± 2.995
0.782AspCys: 0.782 ± 0.913
0.782AspAsp: 0.782 ± 0.913
3.127AspGlu: 3.127 ± 1.547
4.691AspPhe: 4.691 ± 1.596
1.564AspGly: 1.564 ± 0.865
1.564AspHis: 1.564 ± 0.588
1.564AspIle: 1.564 ± 1.099
4.691AspLys: 4.691 ± 3.794
1.564AspLeu: 1.564 ± 1.1
0.782AspMet: 0.782 ± 0.877
1.564AspAsn: 1.564 ± 1.1
3.909AspPro: 3.909 ± 2.46
0.782AspGln: 0.782 ± 0.913
4.691AspArg: 4.691 ± 0.916
3.127AspSer: 3.127 ± 0.745
3.127AspThr: 3.127 ± 2.201
1.564AspVal: 1.564 ± 0.588
0.782AspTrp: 0.782 ± 0.766
3.127AspTyr: 3.127 ± 1.175
0.0AspXaa: 0.0 ± 0.0
Glu
7.037GluAla: 7.037 ± 3.955
1.564GluCys: 1.564 ± 0.865
2.346GluAsp: 2.346 ± 1.368
6.255GluGlu: 6.255 ± 3.561
1.564GluPhe: 1.564 ± 0.588
1.564GluGly: 1.564 ± 0.794
1.564GluHis: 1.564 ± 0.865
3.127GluIle: 3.127 ± 1.175
3.127GluLys: 3.127 ± 2.34
2.346GluLeu: 2.346 ± 1.643
2.346GluMet: 2.346 ± 0.683
3.909GluAsn: 3.909 ± 1.066
1.564GluPro: 1.564 ± 0.865
6.255GluGln: 6.255 ± 1.941
6.255GluArg: 6.255 ± 3.027
2.346GluSer: 2.346 ± 0.683
0.0GluThr: 0.0 ± 0.0
3.127GluVal: 3.127 ± 1.533
0.0GluTrp: 0.0 ± 0.0
3.909GluTyr: 3.909 ± 1.007
0.0GluXaa: 0.0 ± 0.0
Phe
1.564PheAla: 1.564 ± 1.1
2.346PheCys: 2.346 ± 0.842
3.909PheAsp: 3.909 ± 1.481
2.346PheGlu: 2.346 ± 0.761
2.346PhePhe: 2.346 ± 1.751
3.127PheGly: 3.127 ± 1.258
0.0PheHis: 0.0 ± 0.0
2.346PheIle: 2.346 ± 0.842
2.346PheLys: 2.346 ± 1.368
7.819PheLeu: 7.819 ± 2.867
2.346PheMet: 2.346 ± 1.748
2.346PheAsn: 2.346 ± 1.249
2.346PhePro: 2.346 ± 1.249
2.346PheGln: 2.346 ± 1.048
1.564PheArg: 1.564 ± 0.588
3.909PheSer: 3.909 ± 1.268
3.909PheThr: 3.909 ± 2.03
3.909PheVal: 3.909 ± 1.733
0.782PheTrp: 0.782 ± 0.55
2.346PheTyr: 2.346 ± 2.039
0.0PheXaa: 0.0 ± 0.0
Gly
4.691GlyAla: 4.691 ± 3.033
0.782GlyCys: 0.782 ± 0.766
3.127GlyAsp: 3.127 ± 1.296
3.127GlyGlu: 3.127 ± 1.296
2.346GlyPhe: 2.346 ± 0.761
3.909GlyGly: 3.909 ± 1.962
0.0GlyHis: 0.0 ± 0.0
3.909GlyIle: 3.909 ± 0.959
3.127GlyLys: 3.127 ± 1.175
8.6GlyLeu: 8.6 ± 3.395
0.0GlyMet: 0.0 ± 0.0
3.909GlyAsn: 3.909 ± 1.066
2.346GlyPro: 2.346 ± 1.367
1.564GlyGln: 1.564 ± 0.588
0.782GlyArg: 0.782 ± 0.877
7.037GlySer: 7.037 ± 1.622
3.127GlyThr: 3.127 ± 1.547
4.691GlyVal: 4.691 ± 2.417
0.782GlyTrp: 0.782 ± 0.55
3.909GlyTyr: 3.909 ± 1.268
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.782HisAsp: 0.782 ± 0.55
0.782HisGlu: 0.782 ± 0.766
1.564HisPhe: 1.564 ± 1.1
0.782HisGly: 0.782 ± 0.55
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.782HisLys: 0.782 ± 0.766
2.346HisLeu: 2.346 ± 0.842
0.0HisMet: 0.0 ± 0.0
0.782HisAsn: 0.782 ± 0.913
0.782HisPro: 0.782 ± 0.766
0.0HisGln: 0.0 ± 0.0
0.782HisArg: 0.782 ± 0.55
1.564HisSer: 1.564 ± 0.588
0.0HisThr: 0.0 ± 0.0
0.782HisVal: 0.782 ± 0.913
0.0HisTrp: 0.0 ± 0.0
1.564HisTyr: 1.564 ± 1.531
0.0HisXaa: 0.0 ± 0.0
Ile
1.564IleAla: 1.564 ± 1.753
0.0IleCys: 0.0 ± 0.0
1.564IleAsp: 1.564 ± 0.588
3.127IleGlu: 3.127 ± 1.547
3.127IlePhe: 3.127 ± 1.533
3.127IleGly: 3.127 ± 1.182
0.782IleHis: 0.782 ± 0.55
0.782IleIle: 0.782 ± 0.55
1.564IleLys: 1.564 ± 0.588
1.564IleLeu: 1.564 ± 1.1
0.0IleMet: 0.0 ± 0.0
3.127IleAsn: 3.127 ± 1.547
1.564IlePro: 1.564 ± 1.1
3.127IleGln: 3.127 ± 1.296
3.127IleArg: 3.127 ± 1.458
1.564IleSer: 1.564 ± 0.588
1.564IleThr: 1.564 ± 1.1
1.564IleVal: 1.564 ± 0.865
2.346IleTrp: 2.346 ± 0.842
2.346IleTyr: 2.346 ± 1.249
0.0IleXaa: 0.0 ± 0.0
Lys
3.127LysAla: 3.127 ± 2.017
1.564LysCys: 1.564 ± 1.372
2.346LysAsp: 2.346 ± 1.691
2.346LysGlu: 2.346 ± 0.842
3.127LysPhe: 3.127 ± 0.745
4.691LysGly: 4.691 ± 1.91
0.0LysHis: 0.0 ± 0.0
3.127LysIle: 3.127 ± 1.607
9.382LysLys: 9.382 ± 4.765
5.473LysLeu: 5.473 ± 2.335
2.346LysMet: 2.346 ± 1.966
1.564LysAsn: 1.564 ± 1.374
2.346LysPro: 2.346 ± 1.249
3.909LysGln: 3.909 ± 2.371
6.255LysArg: 6.255 ± 3.037
4.691LysSer: 4.691 ± 2.575
3.127LysThr: 3.127 ± 1.182
4.691LysVal: 4.691 ± 2.268
0.0LysTrp: 0.0 ± 0.0
1.564LysTyr: 1.564 ± 1.071
0.0LysXaa: 0.0 ± 0.0
Leu
6.255LeuAla: 6.255 ± 2.461
0.0LeuCys: 0.0 ± 0.0
4.691LeuAsp: 4.691 ± 1.797
0.782LeuGlu: 0.782 ± 0.913
3.127LeuPhe: 3.127 ± 2.329
7.819LeuGly: 7.819 ± 2.948
0.782LeuHis: 0.782 ± 0.766
5.473LeuIle: 5.473 ± 1.196
6.255LeuLys: 6.255 ± 2.154
3.909LeuLeu: 3.909 ± 0.924
3.909LeuMet: 3.909 ± 2.218
5.473LeuAsn: 5.473 ± 1.304
7.819LeuPro: 7.819 ± 0.994
3.127LeuGln: 3.127 ± 0.625
4.691LeuArg: 4.691 ± 1.433
4.691LeuSer: 4.691 ± 1.286
7.037LeuThr: 7.037 ± 2.166
1.564LeuVal: 1.564 ± 1.531
1.564LeuTrp: 1.564 ± 1.531
1.564LeuTyr: 1.564 ± 0.588
0.0LeuXaa: 0.0 ± 0.0
Met
3.127MetAla: 3.127 ± 1.214
1.564MetCys: 1.564 ± 1.372
3.909MetAsp: 3.909 ± 2.254
2.346MetGlu: 2.346 ± 1.368
0.782MetPhe: 0.782 ± 0.913
0.782MetGly: 0.782 ± 0.55
0.782MetHis: 0.782 ± 0.766
0.0MetIle: 0.0 ± 0.0
1.564MetLys: 1.564 ± 1.305
2.346MetLeu: 2.346 ± 2.027
0.0MetMet: 0.0 ± 0.0
1.564MetAsn: 1.564 ± 1.753
1.564MetPro: 1.564 ± 0.588
1.564MetGln: 1.564 ± 1.957
2.346MetArg: 2.346 ± 1.643
1.564MetSer: 1.564 ± 0.794
0.0MetThr: 0.0 ± 0.0
1.564MetVal: 1.564 ± 0.588
0.782MetTrp: 0.782 ± 0.55
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.909AsnAla: 3.909 ± 1.479
0.782AsnCys: 0.782 ± 0.766
1.564AsnAsp: 1.564 ± 1.099
0.782AsnGlu: 0.782 ± 0.55
1.564AsnPhe: 1.564 ± 0.588
2.346AsnGly: 2.346 ± 1.249
0.782AsnHis: 0.782 ± 0.766
2.346AsnIle: 2.346 ± 1.126
1.564AsnLys: 1.564 ± 0.865
5.473AsnLeu: 5.473 ± 1.546
0.0AsnMet: 0.0 ± 0.0
2.346AsnAsn: 2.346 ± 1.085
6.255AsnPro: 6.255 ± 2.065
3.909AsnGln: 3.909 ± 0.579
1.564AsnArg: 1.564 ± 0.794
4.691AsnSer: 4.691 ± 1.433
0.782AsnThr: 0.782 ± 0.877
3.127AsnVal: 3.127 ± 1.73
0.0AsnTrp: 0.0 ± 0.0
3.909AsnTyr: 3.909 ± 1.066
0.0AsnXaa: 0.0 ± 0.0
Pro
3.909ProAla: 3.909 ± 1.393
0.782ProCys: 0.782 ± 0.766
2.346ProAsp: 2.346 ± 0.842
6.255ProGlu: 6.255 ± 3.32
2.346ProPhe: 2.346 ± 1.998
5.473ProGly: 5.473 ± 1.105
1.564ProHis: 1.564 ± 1.531
3.127ProIle: 3.127 ± 2.201
4.691ProLys: 4.691 ± 3.996
2.346ProLeu: 2.346 ± 0.842
3.127ProMet: 3.127 ± 1.12
1.564ProAsn: 1.564 ± 0.794
1.564ProPro: 1.564 ± 0.588
3.909ProGln: 3.909 ± 1.066
3.909ProArg: 3.909 ± 1.774
2.346ProSer: 2.346 ± 1.651
4.691ProThr: 4.691 ± 3.301
5.473ProVal: 5.473 ± 2.497
1.564ProTrp: 1.564 ± 0.588
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.909GlnAla: 3.909 ± 1.268
0.0GlnCys: 0.0 ± 0.0
3.909GlnAsp: 3.909 ± 2.74
3.909GlnGlu: 3.909 ± 1.755
2.346GlnPhe: 2.346 ± 1.751
3.909GlnGly: 3.909 ± 1.962
0.782GlnHis: 0.782 ± 0.913
1.564GlnIle: 1.564 ± 0.794
5.473GlnLys: 5.473 ± 1.304
2.346GlnLeu: 2.346 ± 0.683
0.782GlnMet: 0.782 ± 0.877
4.691GlnAsn: 4.691 ± 2.42
0.782GlnPro: 0.782 ± 0.766
2.346GlnGln: 2.346 ± 1.126
4.691GlnArg: 4.691 ± 1.366
2.346GlnSer: 2.346 ± 1.157
2.346GlnThr: 2.346 ± 0.761
1.564GlnVal: 1.564 ± 1.1
0.782GlnTrp: 0.782 ± 0.55
2.346GlnTyr: 2.346 ± 0.842
0.0GlnXaa: 0.0 ± 0.0
Arg
3.909ArgAla: 3.909 ± 1.962
1.564ArgCys: 1.564 ± 0.588
3.909ArgAsp: 3.909 ± 0.924
5.473ArgGlu: 5.473 ± 2.838
3.127ArgPhe: 3.127 ± 1.258
2.346ArgGly: 2.346 ± 0.842
0.0ArgHis: 0.0 ± 0.0
0.782ArgIle: 0.782 ± 0.55
3.909ArgLys: 3.909 ± 2.371
9.382ArgLeu: 9.382 ± 2.45
3.127ArgMet: 3.127 ± 1.514
3.127ArgAsn: 3.127 ± 1.214
2.346ArgPro: 2.346 ± 1.249
0.782ArgGln: 0.782 ± 0.766
2.346ArgArg: 2.346 ± 1.126
3.909ArgSer: 3.909 ± 2.03
2.346ArgThr: 2.346 ± 0.683
3.909ArgVal: 3.909 ± 0.924
1.564ArgTrp: 1.564 ± 0.588
6.255ArgTyr: 6.255 ± 2.098
0.0ArgXaa: 0.0 ± 0.0
Ser
5.473SerAla: 5.473 ± 2.123
1.564SerCys: 1.564 ± 1.1
0.0SerAsp: 0.0 ± 0.0
2.346SerGlu: 2.346 ± 1.87
5.473SerPhe: 5.473 ± 1.523
4.691SerGly: 4.691 ± 3.418
2.346SerHis: 2.346 ± 1.651
0.782SerIle: 0.782 ± 0.55
3.909SerLys: 3.909 ± 0.924
8.6SerLeu: 8.6 ± 1.973
0.0SerMet: 0.0 ± 0.0
3.127SerAsn: 3.127 ± 1.474
7.819SerPro: 7.819 ± 0.992
1.564SerGln: 1.564 ± 1.531
3.127SerArg: 3.127 ± 0.894
6.255SerSer: 6.255 ± 2.807
7.037SerThr: 7.037 ± 2.337
5.473SerVal: 5.473 ± 2.028
1.564SerTrp: 1.564 ± 0.794
2.346SerTyr: 2.346 ± 2.297
0.0SerXaa: 0.0 ± 0.0
Thr
3.909ThrAla: 3.909 ± 1.777
0.0ThrCys: 0.0 ± 0.0
2.346ThrAsp: 2.346 ± 1.651
3.127ThrGlu: 3.127 ± 1.474
3.127ThrPhe: 3.127 ± 1.547
3.127ThrGly: 3.127 ± 1.547
0.0ThrHis: 0.0 ± 0.0
1.564ThrIle: 1.564 ± 1.1
2.346ThrLys: 2.346 ± 0.842
2.346ThrLeu: 2.346 ± 0.683
0.782ThrMet: 0.782 ± 1.075
0.782ThrAsn: 0.782 ± 0.55
5.473ThrPro: 5.473 ± 3.216
3.909ThrGln: 3.909 ± 1.809
3.127ThrArg: 3.127 ± 1.175
7.819ThrSer: 7.819 ± 3.098
3.127ThrThr: 3.127 ± 2.201
0.782ThrVal: 0.782 ± 0.766
0.0ThrTrp: 0.0 ± 0.0
1.564ThrTyr: 1.564 ± 1.071
0.0ThrXaa: 0.0 ± 0.0
Val
7.819ValAla: 7.819 ± 2.856
3.127ValCys: 3.127 ± 2.428
3.127ValAsp: 3.127 ± 2.201
3.127ValGlu: 3.127 ± 0.894
2.346ValPhe: 2.346 ± 1.816
1.564ValGly: 1.564 ± 0.588
0.0ValHis: 0.0 ± 0.0
1.564ValIle: 1.564 ± 0.865
2.346ValLys: 2.346 ± 0.761
3.909ValLeu: 3.909 ± 1.393
1.564ValMet: 1.564 ± 0.588
3.127ValAsn: 3.127 ± 1.296
4.691ValPro: 4.691 ± 2.449
3.127ValGln: 3.127 ± 0.625
4.691ValArg: 4.691 ± 1.627
2.346ValSer: 2.346 ± 1.643
2.346ValThr: 2.346 ± 0.842
4.691ValVal: 4.691 ± 1.025
0.0ValTrp: 0.0 ± 0.0
2.346ValTyr: 2.346 ± 0.761
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.564TrpAsp: 1.564 ± 0.588
0.0TrpGlu: 0.0 ± 0.0
1.564TrpPhe: 1.564 ± 0.588
0.782TrpGly: 0.782 ± 0.55
1.564TrpHis: 1.564 ± 1.1
0.782TrpIle: 0.782 ± 0.55
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.782TrpAsn: 0.782 ± 0.55
2.346TrpPro: 2.346 ± 0.842
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
3.127TrpSer: 3.127 ± 0.625
0.0TrpThr: 0.0 ± 0.0
0.782TrpVal: 0.782 ± 0.766
0.0TrpTrp: 0.0 ± 0.0
0.782TrpTyr: 0.782 ± 0.766
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.782TyrCys: 0.782 ± 0.55
2.346TyrAsp: 2.346 ± 1.249
6.255TyrGlu: 6.255 ± 2.67
2.346TyrPhe: 2.346 ± 0.842
3.127TyrGly: 3.127 ± 1.175
0.782TyrHis: 0.782 ± 0.766
2.346TyrIle: 2.346 ± 0.842
2.346TyrLys: 2.346 ± 0.842
5.473TyrLeu: 5.473 ± 1.187
2.346TyrMet: 2.346 ± 1.337
2.346TyrAsn: 2.346 ± 1.249
1.564TyrPro: 1.564 ± 1.531
2.346TyrGln: 2.346 ± 1.048
3.127TyrArg: 3.127 ± 1.175
3.909TyrSer: 3.909 ± 1.809
0.0TyrThr: 0.0 ± 0.0
2.346TyrVal: 2.346 ± 1.488
0.782TyrTrp: 0.782 ± 0.55
2.346TyrTyr: 2.346 ± 0.842
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1280 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski