Amino acid dipepetide frequency for Trichinella patagoniensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.517AlaAla: 5.517 ± 0.049
1.534AlaCys: 1.534 ± 0.016
3.571AlaAsp: 3.571 ± 0.024
4.413AlaGlu: 4.413 ± 0.033
2.788AlaPhe: 2.788 ± 0.017
3.356AlaGly: 3.356 ± 0.025
1.337AlaHis: 1.337 ± 0.014
3.408AlaIle: 3.408 ± 0.023
3.564AlaLys: 3.564 ± 0.022
6.134AlaLeu: 6.134 ± 0.038
1.574AlaMet: 1.574 ± 0.016
2.954AlaAsn: 2.954 ± 0.02
2.354AlaPro: 2.354 ± 0.024
2.289AlaGln: 2.289 ± 0.018
2.989AlaArg: 2.989 ± 0.023
5.266AlaSer: 5.266 ± 0.031
3.565AlaThr: 3.565 ± 0.026
5.067AlaVal: 5.067 ± 0.028
0.689AlaTrp: 0.689 ± 0.012
1.837AlaTyr: 1.837 ± 0.017
0.002AlaXaa: 0.002 ± 0.0
Cys
1.446CysAla: 1.446 ± 0.017
0.887CysCys: 0.887 ± 0.016
1.362CysAsp: 1.362 ± 0.022
1.495CysGlu: 1.495 ± 0.021
1.317CysPhe: 1.317 ± 0.015
1.467CysGly: 1.467 ± 0.021
0.692CysHis: 0.692 ± 0.011
1.532CysIle: 1.532 ± 0.021
1.471CysLys: 1.471 ± 0.018
2.622CysLeu: 2.622 ± 0.024
0.571CysMet: 0.571 ± 0.009
1.249CysAsn: 1.249 ± 0.013
1.244CysPro: 1.244 ± 0.024
1.135CysGln: 1.135 ± 0.015
1.642CysArg: 1.642 ± 0.019
2.483CysSer: 2.483 ± 0.029
1.39CysThr: 1.39 ± 0.016
1.529CysVal: 1.529 ± 0.018
0.358CysTrp: 0.358 ± 0.007
0.789CysTyr: 0.789 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
3.273AspAla: 3.273 ± 0.025
1.382AspCys: 1.382 ± 0.022
3.945AspAsp: 3.945 ± 0.034
4.262AspGlu: 4.262 ± 0.031
2.358AspPhe: 2.358 ± 0.017
3.224AspGly: 3.224 ± 0.032
1.234AspHis: 1.234 ± 0.014
2.799AspIle: 2.799 ± 0.02
2.519AspLys: 2.519 ± 0.02
4.648AspLeu: 4.648 ± 0.025
1.158AspMet: 1.158 ± 0.013
2.328AspAsn: 2.328 ± 0.016
2.057AspPro: 2.057 ± 0.02
2.076AspGln: 2.076 ± 0.02
2.737AspArg: 2.737 ± 0.019
4.149AspSer: 4.149 ± 0.027
2.166AspThr: 2.166 ± 0.017
3.685AspVal: 3.685 ± 0.023
0.683AspTrp: 0.683 ± 0.011
1.605AspTyr: 1.605 ± 0.016
0.001AspXaa: 0.001 ± 0.0
Glu
3.841GluAla: 3.841 ± 0.036
1.384GluCys: 1.384 ± 0.021
3.174GluAsp: 3.174 ± 0.026
5.372GluGlu: 5.372 ± 0.046
2.482GluPhe: 2.482 ± 0.02
2.284GluGly: 2.284 ± 0.021
1.403GluHis: 1.403 ± 0.015
3.986GluIle: 3.986 ± 0.033
4.9GluLys: 4.9 ± 0.038
5.811GluLeu: 5.811 ± 0.032
1.929GluMet: 1.929 ± 0.017
4.023GluAsn: 4.023 ± 0.026
2.141GluPro: 2.141 ± 0.019
3.024GluGln: 3.024 ± 0.025
3.563GluArg: 3.563 ± 0.031
4.413GluSer: 4.413 ± 0.03
3.301GluThr: 3.301 ± 0.023
3.503GluVal: 3.503 ± 0.027
0.697GluTrp: 0.697 ± 0.011
1.766GluTyr: 1.766 ± 0.017
0.001GluXaa: 0.001 ± 0.0
Phe
2.82PheAla: 2.82 ± 0.022
1.415PheCys: 1.415 ± 0.017
2.63PheAsp: 2.63 ± 0.019
2.65PheGlu: 2.65 ± 0.02
2.212PhePhe: 2.212 ± 0.021
2.623PheGly: 2.623 ± 0.03
1.315PheHis: 1.315 ± 0.014
2.57PheIle: 2.57 ± 0.021
2.214PheLys: 2.214 ± 0.018
4.356PheLeu: 4.356 ± 0.032
0.892PheMet: 0.892 ± 0.012
2.079PheAsn: 2.079 ± 0.018
1.981PhePro: 1.981 ± 0.017
1.923PheGln: 1.923 ± 0.016
2.369PheArg: 2.369 ± 0.017
3.939PheSer: 3.939 ± 0.028
2.418PheThr: 2.418 ± 0.018
3.098PheVal: 3.098 ± 0.019
0.602PheTrp: 0.602 ± 0.008
1.733PheTyr: 1.733 ± 0.017
0.001PheXaa: 0.001 ± 0.0
Gly
2.73GlyAla: 2.73 ± 0.023
1.278GlyCys: 1.278 ± 0.016
2.59GlyAsp: 2.59 ± 0.022
2.909GlyGlu: 2.909 ± 0.029
2.25GlyPhe: 2.25 ± 0.025
3.352GlyGly: 3.352 ± 0.036
1.292GlyHis: 1.292 ± 0.016
2.926GlyIle: 2.926 ± 0.023
3.363GlyLys: 3.363 ± 0.027
4.058GlyLeu: 4.058 ± 0.027
1.224GlyMet: 1.224 ± 0.013
2.522GlyAsn: 2.522 ± 0.019
1.829GlyPro: 1.829 ± 0.027
2.089GlyGln: 2.089 ± 0.023
3.284GlyArg: 3.284 ± 0.026
4.311GlySer: 4.311 ± 0.028
2.685GlyThr: 2.685 ± 0.02
3.043GlyVal: 3.043 ± 0.023
0.648GlyTrp: 0.648 ± 0.01
1.75GlyTyr: 1.75 ± 0.022
0.0GlyXaa: 0.0 ± 0.0
His
1.418HisAla: 1.418 ± 0.015
0.9HisCys: 0.9 ± 0.013
1.022HisAsp: 1.022 ± 0.011
1.248HisGlu: 1.248 ± 0.015
1.405HisPhe: 1.405 ± 0.015
1.342HisGly: 1.342 ± 0.013
0.949HisHis: 0.949 ± 0.018
1.294HisIle: 1.294 ± 0.013
0.985HisLys: 0.985 ± 0.012
2.719HisLeu: 2.719 ± 0.023
0.553HisMet: 0.553 ± 0.009
0.979HisAsn: 0.979 ± 0.013
1.232HisPro: 1.232 ± 0.015
1.102HisGln: 1.102 ± 0.014
1.538HisArg: 1.538 ± 0.016
2.059HisSer: 2.059 ± 0.017
1.074HisThr: 1.074 ± 0.013
1.605HisVal: 1.605 ± 0.018
0.359HisTrp: 0.359 ± 0.007
0.878HisTyr: 0.878 ± 0.012
0.0HisXaa: 0.0 ± 0.0
Ile
3.658IleAla: 3.658 ± 0.024
1.718IleCys: 1.718 ± 0.019
3.004IleAsp: 3.004 ± 0.019
3.303IleGlu: 3.303 ± 0.025
2.858IlePhe: 2.858 ± 0.021
2.89IleGly: 2.89 ± 0.022
1.345IleHis: 1.345 ± 0.015
3.127IleIle: 3.127 ± 0.024
2.802IleLys: 2.802 ± 0.023
5.357IleLeu: 5.357 ± 0.034
1.211IleMet: 1.211 ± 0.013
2.493IleAsn: 2.493 ± 0.017
2.594IlePro: 2.594 ± 0.02
2.169IleGln: 2.169 ± 0.017
3.159IleArg: 3.159 ± 0.023
4.721IleSer: 4.721 ± 0.028
2.887IleThr: 2.887 ± 0.025
3.64IleVal: 3.64 ± 0.019
0.674IleTrp: 0.674 ± 0.009
1.9IleTyr: 1.9 ± 0.017
0.001IleXaa: 0.001 ± 0.0
Lys
3.521LysAla: 3.521 ± 0.025
1.495LysCys: 1.495 ± 0.02
2.606LysAsp: 2.606 ± 0.02
3.852LysGlu: 3.852 ± 0.029
2.501LysPhe: 2.501 ± 0.022
2.261LysGly: 2.261 ± 0.025
1.502LysHis: 1.502 ± 0.014
3.603LysIle: 3.603 ± 0.024
4.458LysLys: 4.458 ± 0.044
6.087LysLeu: 6.087 ± 0.035
1.75LysMet: 1.75 ± 0.014
3.132LysAsn: 3.132 ± 0.022
2.43LysPro: 2.43 ± 0.024
2.823LysGln: 2.823 ± 0.021
3.868LysArg: 3.868 ± 0.026
4.585LysSer: 4.585 ± 0.028
3.009LysThr: 3.009 ± 0.022
3.3LysVal: 3.3 ± 0.024
0.746LysTrp: 0.746 ± 0.011
1.844LysTyr: 1.844 ± 0.018
0.001LysXaa: 0.001 ± 0.0
Leu
6.046LeuAla: 6.046 ± 0.037
2.506LeuCys: 2.506 ± 0.022
4.561LeuAsp: 4.561 ± 0.029
5.748LeuGlu: 5.748 ± 0.043
4.628LeuPhe: 4.628 ± 0.038
3.864LeuGly: 3.864 ± 0.024
2.72LeuHis: 2.72 ± 0.022
5.409LeuIle: 5.409 ± 0.028
6.507LeuLys: 6.507 ± 0.037
10.712LeuLeu: 10.712 ± 0.063
2.235LeuMet: 2.235 ± 0.02
4.985LeuAsn: 4.985 ± 0.027
4.822LeuPro: 4.822 ± 0.032
4.506LeuGln: 4.506 ± 0.028
5.537LeuArg: 5.537 ± 0.033
7.662LeuSer: 7.662 ± 0.039
5.039LeuThr: 5.039 ± 0.027
5.536LeuVal: 5.536 ± 0.029
1.076LeuTrp: 1.076 ± 0.013
2.939LeuTyr: 2.939 ± 0.025
0.002LeuXaa: 0.002 ± 0.0
Met
1.608MetAla: 1.608 ± 0.015
0.497MetCys: 0.497 ± 0.008
1.29MetAsp: 1.29 ± 0.012
1.637MetGlu: 1.637 ± 0.013
1.01MetPhe: 1.01 ± 0.013
0.911MetGly: 0.911 ± 0.013
0.659MetHis: 0.659 ± 0.009
1.321MetIle: 1.321 ± 0.013
1.766MetLys: 1.766 ± 0.015
2.488MetLeu: 2.488 ± 0.019
0.679MetMet: 0.679 ± 0.01
1.343MetAsn: 1.343 ± 0.015
1.155MetPro: 1.155 ± 0.012
1.172MetGln: 1.172 ± 0.013
1.289MetArg: 1.289 ± 0.013
1.698MetSer: 1.698 ± 0.016
1.258MetThr: 1.258 ± 0.014
1.379MetVal: 1.379 ± 0.012
0.232MetTrp: 0.232 ± 0.005
0.669MetTyr: 0.669 ± 0.01
0.0MetXaa: 0.0 ± 0.0
Asn
3.258AsnAla: 3.258 ± 0.021
1.435AsnCys: 1.435 ± 0.017
2.779AsnAsp: 2.779 ± 0.02
3.233AsnGlu: 3.233 ± 0.023
2.501AsnPhe: 2.501 ± 0.02
3.03AsnGly: 3.03 ± 0.026
1.037AsnHis: 1.037 ± 0.012
2.747AsnIle: 2.747 ± 0.021
2.494AsnLys: 2.494 ± 0.022
4.55AsnLeu: 4.55 ± 0.029
1.155AsnMet: 1.155 ± 0.013
2.974AsnAsn: 2.974 ± 0.032
1.923AsnPro: 1.923 ± 0.019
1.802AsnGln: 1.802 ± 0.016
2.669AsnArg: 2.669 ± 0.017
4.284AsnSer: 4.284 ± 0.029
2.27AsnThr: 2.27 ± 0.017
3.49AsnVal: 3.49 ± 0.024
0.602AsnTrp: 0.602 ± 0.009
1.708AsnTyr: 1.708 ± 0.015
0.001AsnXaa: 0.001 ± 0.0
Pro
2.875ProAla: 2.875 ± 0.024
0.975ProCys: 0.975 ± 0.015
2.272ProAsp: 2.272 ± 0.019
2.619ProGlu: 2.619 ± 0.022
1.934ProPhe: 1.934 ± 0.016
2.382ProGly: 2.382 ± 0.052
0.912ProHis: 0.912 ± 0.009
2.142ProIle: 2.142 ± 0.02
2.358ProLys: 2.358 ± 0.021
4.105ProLeu: 4.105 ± 0.025
0.941ProMet: 0.941 ± 0.013
2.096ProAsn: 2.096 ± 0.019
2.928ProPro: 2.928 ± 0.038
1.504ProGln: 1.504 ± 0.016
1.965ProArg: 1.965 ± 0.018
3.875ProSer: 3.875 ± 0.028
2.642ProThr: 2.642 ± 0.023
3.145ProVal: 3.145 ± 0.021
0.481ProTrp: 0.481 ± 0.009
1.373ProTyr: 1.373 ± 0.016
0.001ProXaa: 0.001 ± 0.0
Gln
2.634GlnAla: 2.634 ± 0.027
1.187GlnCys: 1.187 ± 0.02
1.466GlnAsp: 1.466 ± 0.016
2.186GlnGlu: 2.186 ± 0.019
1.951GlnPhe: 1.951 ± 0.015
1.485GlnGly: 1.485 ± 0.016
1.207GlnHis: 1.207 ± 0.014
2.405GlnIle: 2.405 ± 0.018
2.479GlnLys: 2.479 ± 0.023
4.852GlnLeu: 4.852 ± 0.03
1.205GlnMet: 1.205 ± 0.013
2.084GlnAsn: 2.084 ± 0.016
1.898GlnPro: 1.898 ± 0.02
3.651GlnGln: 3.651 ± 0.069
2.665GlnArg: 2.665 ± 0.02
3.298GlnSer: 3.298 ± 0.022
2.126GlnThr: 2.126 ± 0.016
2.088GlnVal: 2.088 ± 0.02
0.592GlnTrp: 0.592 ± 0.009
1.291GlnTyr: 1.291 ± 0.013
0.0GlnXaa: 0.0 ± 0.0
Arg
3.094ArgAla: 3.094 ± 0.023
1.638ArgCys: 1.638 ± 0.021
2.437ArgAsp: 2.437 ± 0.02
3.046ArgGlu: 3.046 ± 0.026
2.603ArgPhe: 2.603 ± 0.02
2.512ArgGly: 2.512 ± 0.022
1.57ArgHis: 1.57 ± 0.016
3.277ArgIle: 3.277 ± 0.022
3.687ArgLys: 3.687 ± 0.026
5.915ArgLeu: 5.915 ± 0.032
1.458ArgMet: 1.458 ± 0.016
2.733ArgAsn: 2.733 ± 0.021
2.389ArgPro: 2.389 ± 0.018
2.621ArgGln: 2.621 ± 0.023
4.786ArgArg: 4.786 ± 0.043
4.494ArgSer: 4.494 ± 0.035
2.805ArgThr: 2.805 ± 0.019
3.022ArgVal: 3.022 ± 0.024
0.835ArgTrp: 0.835 ± 0.014
1.729ArgTyr: 1.729 ± 0.014
0.0ArgXaa: 0.0 ± 0.0
Ser
5.541SerAla: 5.541 ± 0.027
2.12SerCys: 2.12 ± 0.021
4.471SerAsp: 4.471 ± 0.029
4.869SerGlu: 4.869 ± 0.036
3.635SerPhe: 3.635 ± 0.021
4.613SerGly: 4.613 ± 0.028
1.644SerHis: 1.644 ± 0.015
4.203SerIle: 4.203 ± 0.022
4.656SerLys: 4.656 ± 0.029
7.462SerLeu: 7.462 ± 0.038
1.823SerMet: 1.823 ± 0.014
4.171SerAsn: 4.171 ± 0.028
3.561SerPro: 3.561 ± 0.033
2.832SerGln: 2.832 ± 0.021
4.359SerArg: 4.359 ± 0.031
9.509SerSer: 9.509 ± 0.073
5.264SerThr: 5.264 ± 0.035
5.706SerVal: 5.706 ± 0.031
0.916SerTrp: 0.916 ± 0.012
2.225SerTyr: 2.225 ± 0.02
0.001SerXaa: 0.001 ± 0.0
Thr
4.185ThrAla: 4.185 ± 0.029
1.365ThrCys: 1.365 ± 0.02
2.83ThrAsp: 2.83 ± 0.018
3.157ThrGlu: 3.157 ± 0.022
2.419ThrPhe: 2.419 ± 0.019
2.945ThrGly: 2.945 ± 0.023
0.949ThrHis: 0.949 ± 0.012
2.85ThrIle: 2.85 ± 0.021
2.733ThrLys: 2.733 ± 0.022
5.086ThrLeu: 5.086 ± 0.028
1.266ThrMet: 1.266 ± 0.013
2.469ThrAsn: 2.469 ± 0.018
2.405ThrPro: 2.405 ± 0.023
1.506ThrGln: 1.506 ± 0.015
2.262ThrArg: 2.262 ± 0.022
4.525ThrSer: 4.525 ± 0.026
3.882ThrThr: 3.882 ± 0.042
4.462ThrVal: 4.462 ± 0.029
0.552ThrTrp: 0.552 ± 0.01
1.406ThrTyr: 1.406 ± 0.015
0.0ThrXaa: 0.0 ± 0.0
Val
4.262ValAla: 4.262 ± 0.024
1.68ValCys: 1.68 ± 0.022
4.097ValAsp: 4.097 ± 0.026
4.657ValGlu: 4.657 ± 0.034
2.64ValPhe: 2.64 ± 0.018
3.394ValGly: 3.394 ± 0.022
1.762ValHis: 1.762 ± 0.015
3.51ValIle: 3.51 ± 0.023
3.778ValLys: 3.778 ± 0.025
5.768ValLeu: 5.768 ± 0.032
1.384ValMet: 1.384 ± 0.013
3.076ValAsn: 3.076 ± 0.022
2.743ValPro: 2.743 ± 0.022
2.807ValGln: 2.807 ± 0.021
3.428ValArg: 3.428 ± 0.027
4.819ValSer: 4.819 ± 0.026
3.308ValThr: 3.308 ± 0.022
4.667ValVal: 4.667 ± 0.032
0.735ValTrp: 0.735 ± 0.012
1.879ValTyr: 1.879 ± 0.016
0.0ValXaa: 0.0 ± 0.0
Trp
0.599TrpAla: 0.599 ± 0.011
0.28TrpCys: 0.28 ± 0.006
0.545TrpAsp: 0.545 ± 0.01
0.553TrpGlu: 0.553 ± 0.009
0.579TrpPhe: 0.579 ± 0.009
0.402TrpGly: 0.402 ± 0.008
0.335TrpHis: 0.335 ± 0.008
0.796TrpIle: 0.796 ± 0.011
0.968TrpLys: 0.968 ± 0.011
1.319TrpLeu: 1.319 ± 0.014
0.339TrpMet: 0.339 ± 0.006
0.77TrpAsn: 0.77 ± 0.011
0.512TrpPro: 0.512 ± 0.007
0.537TrpGln: 0.537 ± 0.008
0.749TrpArg: 0.749 ± 0.009
1.004TrpSer: 1.004 ± 0.014
0.707TrpThr: 0.707 ± 0.01
0.514TrpVal: 0.514 ± 0.008
0.187TrpTrp: 0.187 ± 0.005
0.429TrpTyr: 0.429 ± 0.011
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.882TyrAla: 1.882 ± 0.015
1.006TyrCys: 1.006 ± 0.015
1.635TyrAsp: 1.635 ± 0.016
1.789TyrGlu: 1.789 ± 0.014
1.77TyrPhe: 1.77 ± 0.018
1.797TyrGly: 1.797 ± 0.017
0.796TyrHis: 0.796 ± 0.01
1.603TyrIle: 1.603 ± 0.016
1.67TyrLys: 1.67 ± 0.018
2.991TyrLeu: 2.991 ± 0.026
0.71TyrMet: 0.71 ± 0.009
1.478TyrAsn: 1.478 ± 0.017
1.327TyrPro: 1.327 ± 0.015
1.183TyrGln: 1.183 ± 0.014
1.796TyrArg: 1.796 ± 0.014
2.486TyrSer: 2.486 ± 0.017
1.458TyrThr: 1.458 ± 0.016
1.91TyrVal: 1.91 ± 0.016
0.461TyrTrp: 0.461 ± 0.01
1.208TyrTyr: 1.208 ± 0.015
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.001XaaAsp: 0.001 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.001XaaPhe: 0.001 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.001XaaIle: 0.001 ± 0.0
0.002XaaLys: 0.002 ± 0.0
0.001XaaLeu: 0.001 ± 0.0
0.001XaaMet: 0.001 ± 0.0
0.001XaaAsn: 0.001 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.001XaaSer: 0.001 ± 0.0
0.001XaaThr: 0.001 ± 0.0
0.001XaaVal: 0.001 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.013XaaXaa: 0.013 ± 0.005
Statistics based on 18337 proteins (8154253 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski