Amino acid dipepetide frequency for Simian adenovirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.239AlaAla: 10.239 ± 1.825
1.168AlaCys: 1.168 ± 0.401
3.323AlaAsp: 3.323 ± 0.666
3.593AlaGlu: 3.593 ± 0.682
2.784AlaPhe: 2.784 ± 0.483
4.581AlaGly: 4.581 ± 0.777
1.706AlaHis: 1.706 ± 0.316
3.682AlaIle: 3.682 ± 0.674
1.976AlaLys: 1.976 ± 0.465
8.532AlaLeu: 8.532 ± 0.986
1.257AlaMet: 1.257 ± 0.352
2.784AlaAsn: 2.784 ± 0.791
5.748AlaPro: 5.748 ± 0.797
3.503AlaGln: 3.503 ± 0.464
5.209AlaArg: 5.209 ± 0.959
4.94AlaSer: 4.94 ± 0.676
4.491AlaThr: 4.491 ± 0.508
6.467AlaVal: 6.467 ± 0.685
0.719AlaTrp: 0.719 ± 0.252
2.515AlaTyr: 2.515 ± 0.492
0.0AlaXaa: 0.0 ± 0.0
Cys
1.437CysAla: 1.437 ± 0.461
0.539CysCys: 0.539 ± 0.277
0.988CysAsp: 0.988 ± 0.28
0.988CysGlu: 0.988 ± 0.351
0.808CysPhe: 0.808 ± 0.262
1.527CysGly: 1.527 ± 0.461
0.539CysHis: 0.539 ± 0.217
0.808CysIle: 0.808 ± 0.265
0.539CysLys: 0.539 ± 0.235
1.886CysLeu: 1.886 ± 0.471
0.539CysMet: 0.539 ± 0.215
0.988CysAsn: 0.988 ± 0.364
1.078CysPro: 1.078 ± 0.295
0.808CysGln: 0.808 ± 0.299
0.898CysArg: 0.898 ± 0.307
1.796CysSer: 1.796 ± 0.458
0.898CysThr: 0.898 ± 0.252
1.257CysVal: 1.257 ± 0.368
0.359CysTrp: 0.359 ± 0.222
0.719CysTyr: 0.719 ± 0.294
0.0CysXaa: 0.0 ± 0.0
Asp
3.144AspAla: 3.144 ± 0.529
1.168AspCys: 1.168 ± 0.355
1.976AspAsp: 1.976 ± 0.632
3.323AspGlu: 3.323 ± 0.727
2.156AspPhe: 2.156 ± 0.381
2.694AspGly: 2.694 ± 0.598
1.257AspHis: 1.257 ± 0.389
1.437AspIle: 1.437 ± 0.312
1.078AspLys: 1.078 ± 0.291
4.76AspLeu: 4.76 ± 0.916
1.617AspMet: 1.617 ± 0.447
1.886AspAsn: 1.886 ± 0.415
3.144AspPro: 3.144 ± 0.498
0.808AspGln: 0.808 ± 0.23
3.593AspArg: 3.593 ± 0.75
3.503AspSer: 3.503 ± 0.654
2.425AspThr: 2.425 ± 0.461
3.952AspVal: 3.952 ± 0.548
1.078AspTrp: 1.078 ± 0.308
2.335AspTyr: 2.335 ± 0.437
0.0AspXaa: 0.0 ± 0.0
Glu
4.85GluAla: 4.85 ± 1.214
0.808GluCys: 0.808 ± 0.304
3.682GluAsp: 3.682 ± 0.67
8.443GluGlu: 8.443 ± 1.436
1.706GluPhe: 1.706 ± 0.393
3.413GluGly: 3.413 ± 0.501
1.617GluHis: 1.617 ± 0.426
2.515GluIle: 2.515 ± 0.441
2.515GluLys: 2.515 ± 0.755
5.03GluLeu: 5.03 ± 0.69
1.347GluMet: 1.347 ± 0.436
2.874GluAsn: 2.874 ± 0.714
3.862GluPro: 3.862 ± 0.864
2.245GluGln: 2.245 ± 0.538
3.593GluArg: 3.593 ± 0.821
2.066GluSer: 2.066 ± 0.472
3.862GluThr: 3.862 ± 0.54
4.221GluVal: 4.221 ± 0.951
0.898GluTrp: 0.898 ± 0.285
1.347GluTyr: 1.347 ± 0.274
0.0GluXaa: 0.0 ± 0.0
Phe
2.784PheAla: 2.784 ± 0.421
0.629PheCys: 0.629 ± 0.262
2.425PheAsp: 2.425 ± 0.441
1.347PheGlu: 1.347 ± 0.42
2.066PhePhe: 2.066 ± 0.398
1.347PheGly: 1.347 ± 0.477
1.168PheHis: 1.168 ± 0.264
1.168PheIle: 1.168 ± 0.298
1.257PheLys: 1.257 ± 0.408
3.862PheLeu: 3.862 ± 0.627
1.617PheMet: 1.617 ± 0.312
2.425PheAsn: 2.425 ± 0.592
2.066PhePro: 2.066 ± 0.362
1.886PheGln: 1.886 ± 0.37
2.784PheArg: 2.784 ± 0.451
3.233PheSer: 3.233 ± 0.535
2.425PheThr: 2.425 ± 0.482
3.772PheVal: 3.772 ± 0.486
0.359PheTrp: 0.359 ± 0.159
1.796PheTyr: 1.796 ± 0.414
0.0PheXaa: 0.0 ± 0.0
Gly
4.131GlyAla: 4.131 ± 0.576
0.898GlyCys: 0.898 ± 0.252
3.413GlyAsp: 3.413 ± 0.489
3.593GlyGlu: 3.593 ± 0.674
2.245GlyPhe: 2.245 ± 0.44
4.94GlyGly: 4.94 ± 1.316
1.706GlyHis: 1.706 ± 0.495
3.233GlyIle: 3.233 ± 0.493
1.886GlyLys: 1.886 ± 0.415
5.748GlyLeu: 5.748 ± 1.386
1.257GlyMet: 1.257 ± 0.386
2.784GlyAsn: 2.784 ± 0.932
2.874GlyPro: 2.874 ± 0.496
2.964GlyGln: 2.964 ± 0.69
5.209GlyArg: 5.209 ± 0.754
4.311GlySer: 4.311 ± 0.53
2.515GlyThr: 2.515 ± 0.48
4.581GlyVal: 4.581 ± 0.758
0.898GlyTrp: 0.898 ± 0.27
1.886GlyTyr: 1.886 ± 0.538
0.0GlyXaa: 0.0 ± 0.0
His
1.527HisAla: 1.527 ± 0.485
0.898HisCys: 0.898 ± 0.352
1.257HisAsp: 1.257 ± 0.26
1.078HisGlu: 1.078 ± 0.376
0.898HisPhe: 0.898 ± 0.273
1.976HisGly: 1.976 ± 0.368
0.629HisHis: 0.629 ± 0.244
1.347HisIle: 1.347 ± 0.326
0.629HisLys: 0.629 ± 0.182
3.233HisLeu: 3.233 ± 0.804
0.18HisMet: 0.18 ± 0.135
0.988HisAsn: 0.988 ± 0.334
1.617HisPro: 1.617 ± 0.455
0.719HisGln: 0.719 ± 0.209
2.066HisArg: 2.066 ± 0.403
1.437HisSer: 1.437 ± 0.364
0.898HisThr: 0.898 ± 0.283
1.168HisVal: 1.168 ± 0.354
0.269HisTrp: 0.269 ± 0.176
0.898HisTyr: 0.898 ± 0.25
0.0HisXaa: 0.0 ± 0.0
Ile
3.054IleAla: 3.054 ± 0.613
0.808IleCys: 0.808 ± 0.272
2.066IleAsp: 2.066 ± 0.404
1.527IleGlu: 1.527 ± 0.314
1.976IlePhe: 1.976 ± 0.407
1.886IleGly: 1.886 ± 0.584
0.988IleHis: 0.988 ± 0.328
1.617IleIle: 1.617 ± 0.398
2.245IleLys: 2.245 ± 0.646
3.772IleLeu: 3.772 ± 0.544
0.629IleMet: 0.629 ± 0.226
2.425IleAsn: 2.425 ± 0.471
2.694IlePro: 2.694 ± 0.511
1.347IleGln: 1.347 ± 0.373
2.425IleArg: 2.425 ± 0.688
3.593IleSer: 3.593 ± 0.65
2.156IleThr: 2.156 ± 0.43
2.964IleVal: 2.964 ± 0.47
0.359IleTrp: 0.359 ± 0.169
1.078IleTyr: 1.078 ± 0.341
0.0IleXaa: 0.0 ± 0.0
Lys
1.527LysAla: 1.527 ± 0.254
0.449LysCys: 0.449 ± 0.291
0.988LysAsp: 0.988 ± 0.311
2.425LysGlu: 2.425 ± 0.405
1.796LysPhe: 1.796 ± 0.326
2.605LysGly: 2.605 ± 0.538
0.808LysHis: 0.808 ± 0.3
2.335LysIle: 2.335 ± 0.669
1.347LysLys: 1.347 ± 0.407
2.425LysLeu: 2.425 ± 0.525
0.719LysMet: 0.719 ± 0.286
2.156LysAsn: 2.156 ± 0.38
2.066LysPro: 2.066 ± 0.376
1.078LysGln: 1.078 ± 0.353
3.413LysArg: 3.413 ± 0.682
2.066LysSer: 2.066 ± 0.473
2.335LysThr: 2.335 ± 0.377
1.976LysVal: 1.976 ± 0.509
0.359LysTrp: 0.359 ± 0.193
1.168LysTyr: 1.168 ± 0.362
0.0LysXaa: 0.0 ± 0.0
Leu
7.544LeuAla: 7.544 ± 0.93
2.066LeuCys: 2.066 ± 0.52
4.401LeuAsp: 4.401 ± 0.701
5.389LeuGlu: 5.389 ± 0.795
2.694LeuPhe: 2.694 ± 0.71
5.928LeuGly: 5.928 ± 0.607
3.054LeuHis: 3.054 ± 0.502
2.784LeuIle: 2.784 ± 0.463
4.581LeuLys: 4.581 ± 0.745
10.329LeuLeu: 10.329 ± 1.091
2.335LeuMet: 2.335 ± 0.408
4.85LeuAsn: 4.85 ± 0.816
7.006LeuPro: 7.006 ± 0.798
6.107LeuGln: 6.107 ± 1.233
7.185LeuArg: 7.185 ± 0.983
6.736LeuSer: 6.736 ± 0.974
6.018LeuThr: 6.018 ± 0.869
4.76LeuVal: 4.76 ± 0.837
1.347LeuTrp: 1.347 ± 0.362
3.862LeuTyr: 3.862 ± 0.641
0.0LeuXaa: 0.0 ± 0.0
Met
2.515MetAla: 2.515 ± 0.393
0.269MetCys: 0.269 ± 0.201
0.898MetAsp: 0.898 ± 0.258
1.976MetGlu: 1.976 ± 0.473
0.719MetPhe: 0.719 ± 0.283
1.347MetGly: 1.347 ± 0.238
0.629MetHis: 0.629 ± 0.295
0.898MetIle: 0.898 ± 0.264
0.629MetLys: 0.629 ± 0.236
1.617MetLeu: 1.617 ± 0.586
0.629MetMet: 0.629 ± 0.203
1.078MetAsn: 1.078 ± 0.37
1.886MetPro: 1.886 ± 0.454
0.719MetGln: 0.719 ± 0.316
1.347MetArg: 1.347 ± 0.446
1.168MetSer: 1.168 ± 0.27
1.617MetThr: 1.617 ± 0.432
1.078MetVal: 1.078 ± 0.407
0.269MetTrp: 0.269 ± 0.15
0.808MetTyr: 0.808 ± 0.257
0.0MetXaa: 0.0 ± 0.0
Asn
3.054AsnAla: 3.054 ± 0.549
1.347AsnCys: 1.347 ± 0.361
2.245AsnAsp: 2.245 ± 0.617
2.066AsnGlu: 2.066 ± 0.312
2.964AsnPhe: 2.964 ± 0.486
2.694AsnGly: 2.694 ± 0.71
1.078AsnHis: 1.078 ± 0.379
2.425AsnIle: 2.425 ± 0.665
1.257AsnLys: 1.257 ± 0.344
4.042AsnLeu: 4.042 ± 0.63
1.257AsnMet: 1.257 ± 0.444
2.335AsnAsn: 2.335 ± 0.986
3.503AsnPro: 3.503 ± 0.631
1.796AsnGln: 1.796 ± 0.406
2.784AsnArg: 2.784 ± 0.514
2.694AsnSer: 2.694 ± 0.626
3.593AsnThr: 3.593 ± 0.96
2.605AsnVal: 2.605 ± 0.579
0.719AsnTrp: 0.719 ± 0.276
2.066AsnTyr: 2.066 ± 0.493
0.0AsnXaa: 0.0 ± 0.0
Pro
6.018ProAla: 6.018 ± 0.759
0.808ProCys: 0.808 ± 0.342
3.144ProAsp: 3.144 ± 0.552
5.299ProGlu: 5.299 ± 0.693
2.425ProPhe: 2.425 ± 0.45
4.131ProGly: 4.131 ± 0.594
1.168ProHis: 1.168 ± 0.303
2.335ProIle: 2.335 ± 0.514
2.784ProLys: 2.784 ± 0.642
5.03ProLeu: 5.03 ± 0.752
1.706ProMet: 1.706 ± 0.395
2.245ProAsn: 2.245 ± 0.506
7.095ProPro: 7.095 ± 0.98
3.233ProGln: 3.233 ± 0.691
4.85ProArg: 4.85 ± 0.876
5.658ProSer: 5.658 ± 0.713
3.413ProThr: 3.413 ± 0.608
4.401ProVal: 4.401 ± 0.767
0.898ProTrp: 0.898 ± 0.306
2.066ProTyr: 2.066 ± 0.426
0.0ProXaa: 0.0 ± 0.0
Gln
4.85GlnAla: 4.85 ± 0.733
0.898GlnCys: 0.898 ± 0.349
1.617GlnAsp: 1.617 ± 0.331
2.245GlnGlu: 2.245 ± 0.386
1.078GlnPhe: 1.078 ± 0.341
1.617GlnGly: 1.617 ± 0.323
0.808GlnHis: 0.808 ± 0.234
1.706GlnIle: 1.706 ± 0.454
1.437GlnLys: 1.437 ± 0.326
5.479GlnLeu: 5.479 ± 0.906
1.078GlnMet: 1.078 ± 0.294
1.886GlnAsn: 1.886 ± 0.543
3.323GlnPro: 3.323 ± 0.675
2.066GlnGln: 2.066 ± 0.409
3.413GlnArg: 3.413 ± 0.48
3.682GlnSer: 3.682 ± 0.629
3.144GlnThr: 3.144 ± 0.722
2.515GlnVal: 2.515 ± 0.461
0.629GlnTrp: 0.629 ± 0.241
0.629GlnTyr: 0.629 ± 0.259
0.0GlnXaa: 0.0 ± 0.0
Arg
5.748ArgAla: 5.748 ± 0.941
1.886ArgCys: 1.886 ± 0.513
3.952ArgAsp: 3.952 ± 0.829
3.952ArgGlu: 3.952 ± 0.881
2.605ArgPhe: 2.605 ± 0.443
5.299ArgGly: 5.299 ± 0.987
1.617ArgHis: 1.617 ± 0.436
1.886ArgIle: 1.886 ± 0.385
2.156ArgLys: 2.156 ± 0.428
7.095ArgLeu: 7.095 ± 0.979
1.168ArgMet: 1.168 ± 0.321
3.503ArgAsn: 3.503 ± 0.496
4.491ArgPro: 4.491 ± 0.899
3.144ArgGln: 3.144 ± 0.465
9.431ArgArg: 9.431 ± 1.996
3.952ArgSer: 3.952 ± 0.787
3.323ArgThr: 3.323 ± 0.646
4.581ArgVal: 4.581 ± 0.712
1.347ArgTrp: 1.347 ± 0.363
2.066ArgTyr: 2.066 ± 0.477
0.0ArgXaa: 0.0 ± 0.0
Ser
5.658SerAla: 5.658 ± 0.726
1.617SerCys: 1.617 ± 0.384
2.874SerAsp: 2.874 ± 0.554
3.503SerGlu: 3.503 ± 0.727
2.874SerPhe: 2.874 ± 0.468
4.67SerGly: 4.67 ± 0.868
1.437SerHis: 1.437 ± 0.419
2.964SerIle: 2.964 ± 0.655
1.706SerLys: 1.706 ± 0.332
7.006SerLeu: 7.006 ± 1.019
0.988SerMet: 0.988 ± 0.352
3.593SerAsn: 3.593 ± 0.493
4.401SerPro: 4.401 ± 0.788
2.694SerGln: 2.694 ± 0.407
4.581SerArg: 4.581 ± 0.68
6.467SerSer: 6.467 ± 0.774
4.401SerThr: 4.401 ± 0.722
4.042SerVal: 4.042 ± 0.53
0.539SerTrp: 0.539 ± 0.205
2.694SerTyr: 2.694 ± 0.595
0.0SerXaa: 0.0 ± 0.0
Thr
3.593ThrAla: 3.593 ± 0.557
1.347ThrCys: 1.347 ± 0.415
2.425ThrAsp: 2.425 ± 0.32
2.694ThrGlu: 2.694 ± 0.541
3.323ThrPhe: 3.323 ± 0.619
3.862ThrGly: 3.862 ± 0.827
1.347ThrHis: 1.347 ± 0.289
2.874ThrIle: 2.874 ± 0.769
1.706ThrLys: 1.706 ± 0.372
8.802ThrLeu: 8.802 ± 1.342
1.168ThrMet: 1.168 ± 0.197
2.156ThrAsn: 2.156 ± 0.632
4.221ThrPro: 4.221 ± 0.593
2.874ThrGln: 2.874 ± 0.482
2.605ThrArg: 2.605 ± 0.511
2.874ThrSer: 2.874 ± 0.554
3.144ThrThr: 3.144 ± 0.646
3.503ThrVal: 3.503 ± 0.54
1.078ThrTrp: 1.078 ± 0.282
2.964ThrTyr: 2.964 ± 0.59
0.0ThrXaa: 0.0 ± 0.0
Val
5.03ValAla: 5.03 ± 0.645
0.988ValCys: 0.988 ± 0.288
3.503ValAsp: 3.503 ± 0.839
4.76ValGlu: 4.76 ± 0.833
2.425ValPhe: 2.425 ± 0.44
3.503ValGly: 3.503 ± 0.612
1.078ValHis: 1.078 ± 0.327
2.245ValIle: 2.245 ± 0.399
1.886ValLys: 1.886 ± 0.419
5.03ValLeu: 5.03 ± 0.632
1.257ValMet: 1.257 ± 0.384
2.694ValAsn: 2.694 ± 0.578
4.85ValPro: 4.85 ± 0.531
3.144ValGln: 3.144 ± 0.608
4.67ValArg: 4.67 ± 1.141
4.221ValSer: 4.221 ± 0.585
4.131ValThr: 4.131 ± 0.395
4.221ValVal: 4.221 ± 1.023
1.078ValTrp: 1.078 ± 0.336
3.413ValTyr: 3.413 ± 0.536
0.0ValXaa: 0.0 ± 0.0
Trp
0.269TrpAla: 0.269 ± 0.15
0.18TrpCys: 0.18 ± 0.13
0.719TrpAsp: 0.719 ± 0.219
0.898TrpGlu: 0.898 ± 0.416
0.449TrpPhe: 0.449 ± 0.257
0.808TrpGly: 0.808 ± 0.26
0.18TrpHis: 0.18 ± 0.131
0.449TrpIle: 0.449 ± 0.179
0.988TrpLys: 0.988 ± 0.322
1.437TrpLeu: 1.437 ± 0.41
0.359TrpMet: 0.359 ± 0.167
0.988TrpAsn: 0.988 ± 0.261
0.808TrpPro: 0.808 ± 0.242
0.808TrpGln: 0.808 ± 0.255
0.719TrpArg: 0.719 ± 0.231
1.527TrpSer: 1.527 ± 0.413
1.347TrpThr: 1.347 ± 0.338
0.269TrpVal: 0.269 ± 0.168
0.18TrpTrp: 0.18 ± 0.117
0.449TrpTyr: 0.449 ± 0.195
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.245TyrAla: 2.245 ± 0.42
0.629TyrCys: 0.629 ± 0.21
1.437TyrAsp: 1.437 ± 0.424
1.886TyrGlu: 1.886 ± 0.511
2.425TyrPhe: 2.425 ± 0.507
2.245TyrGly: 2.245 ± 0.406
0.898TyrHis: 0.898 ± 0.268
0.898TyrIle: 0.898 ± 0.284
1.437TyrLys: 1.437 ± 0.343
3.862TyrLeu: 3.862 ± 0.606
0.898TyrMet: 0.898 ± 0.283
1.886TyrAsn: 1.886 ± 0.576
1.976TyrPro: 1.976 ± 0.409
2.156TyrGln: 2.156 ± 0.442
2.425TyrArg: 2.425 ± 0.426
2.784TyrSer: 2.784 ± 0.495
2.425TyrThr: 2.425 ± 0.451
1.796TyrVal: 1.796 ± 0.42
0.449TyrTrp: 0.449 ± 0.16
0.719TyrTyr: 0.719 ± 0.205
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 34 proteins (11135 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski