Amino acid dipepetide frequency for Xylanimonas oleitrophica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	24.301AlaAla: 24.301 ± 0.298	0.851AlaCys: 0.851 ± 0.039	8.711AlaAsp: 8.711 ± 0.107	8.668AlaGlu: 8.668 ± 0.128	3.439AlaPhe: 3.439 ± 0.063	15.138AlaGly: 15.138 ± 0.161	2.777AlaHis: 2.777 ± 0.056	3.462AlaIle: 3.462 ± 0.075	2.004AlaLys: 2.004 ± 0.059	15.28AlaLeu: 15.28 ± 0.197	2.552AlaMet: 2.552 ± 0.055	1.705AlaAsn: 1.705 ± 0.043	8.34AlaPro: 8.34 ± 0.156	4.613AlaGln: 4.613 ± 0.082	11.493AlaArg: 11.493 ± 0.166	6.628AlaSer: 6.628 ± 0.089	8.067AlaThr: 8.067 ± 0.105	14.395AlaVal: 14.395 ± 0.161	2.236AlaTrp: 2.236 ± 0.047	2.333AlaTyr: 2.333 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.698CysAla: 0.698 ± 0.036	0.072CysCys: 0.072 ± 0.01	0.313CysAsp: 0.313 ± 0.018	0.265CysGlu: 0.265 ± 0.017	0.136CysPhe: 0.136 ± 0.012	0.663CysGly: 0.663 ± 0.031	0.098CysHis: 0.098 ± 0.009	0.114CysIle: 0.114 ± 0.011	0.049CysLys: 0.049 ± 0.007	0.452CysLeu: 0.452 ± 0.023	0.072CysMet: 0.072 ± 0.008	0.071CysAsn: 0.071 ± 0.008	0.335CysPro: 0.335 ± 0.02	0.118CysGln: 0.118 ± 0.011	0.369CysArg: 0.369 ± 0.023	0.348CysSer: 0.348 ± 0.024	0.389CysThr: 0.389 ± 0.024	0.478CysVal: 0.478 ± 0.022	0.076CysTrp: 0.076 ± 0.009	0.093CysTyr: 0.093 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	9.164AspAla: 9.164 ± 0.118	0.23AspCys: 0.23 ± 0.014	4.441AspAsp: 4.441 ± 0.082	4.105AspGlu: 4.105 ± 0.074	1.251AspPhe: 1.251 ± 0.04	7.021AspGly: 7.021 ± 0.095	1.301AspHis: 1.301 ± 0.035	1.299AspIle: 1.299 ± 0.039	0.789AspLys: 0.789 ± 0.03	6.647AspLeu: 6.647 ± 0.088	0.677AspMet: 0.677 ± 0.025	0.665AspAsn: 0.665 ± 0.026	4.614AspPro: 4.614 ± 0.072	1.53AspGln: 1.53 ± 0.041	4.105AspArg: 4.105 ± 0.068	1.953AspSer: 1.953 ± 0.043	2.593AspThr: 2.593 ± 0.05	7.072AspVal: 7.072 ± 0.087	0.816AspTrp: 0.816 ± 0.028	0.984AspTyr: 0.984 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	8.133GluAla: 8.133 ± 0.124	0.223GluCys: 0.223 ± 0.015	2.904GluAsp: 2.904 ± 0.06	3.183GluGlu: 3.183 ± 0.065	1.082GluPhe: 1.082 ± 0.038	4.481GluGly: 4.481 ± 0.074	1.827GluHis: 1.827 ± 0.045	2.179GluIle: 2.179 ± 0.047	1.072GluLys: 1.072 ± 0.036	6.188GluLeu: 6.188 ± 0.099	0.816GluMet: 0.816 ± 0.026	0.924GluAsn: 0.924 ± 0.032	3.78GluPro: 3.78 ± 0.07	2.439GluGln: 2.439 ± 0.06	5.703GluArg: 5.703 ± 0.09	2.167GluSer: 2.167 ± 0.047	2.857GluThr: 2.857 ± 0.059	5.324GluVal: 5.324 ± 0.076	0.661GluTrp: 0.661 ± 0.03	0.931GluTyr: 0.931 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.409PheAla: 3.409 ± 0.066	0.158PheCys: 0.158 ± 0.013	1.828PheAsp: 1.828 ± 0.045	1.465PheGlu: 1.465 ± 0.039	0.795PhePhe: 0.795 ± 0.032	2.613PheGly: 2.613 ± 0.053	0.465PheHis: 0.465 ± 0.022	0.534PheIle: 0.534 ± 0.029	0.341PheLys: 0.341 ± 0.02	2.351PheLeu: 2.351 ± 0.053	0.327PheMet: 0.327 ± 0.018	0.435PheAsn: 0.435 ± 0.02	1.21PhePro: 1.21 ± 0.032	0.607PheGln: 0.607 ± 0.026	1.499PheArg: 1.499 ± 0.038	1.324PheSer: 1.324 ± 0.039	1.694PheThr: 1.694 ± 0.052	2.546PheVal: 2.546 ± 0.056	0.42PheTrp: 0.42 ± 0.023	0.512PheTyr: 0.512 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	13.134GlyAla: 13.134 ± 0.152	0.548GlyCys: 0.548 ± 0.024	5.373GlyAsp: 5.373 ± 0.076	5.258GlyGlu: 5.258 ± 0.078	2.686GlyPhe: 2.686 ± 0.054	8.919GlyGly: 8.919 ± 0.122	2.094GlyHis: 2.094 ± 0.05	3.08GlyIle: 3.08 ± 0.062	1.823GlyLys: 1.823 ± 0.05	9.3GlyLeu: 9.3 ± 0.107	1.861GlyMet: 1.861 ± 0.044	1.382GlyAsn: 1.382 ± 0.048	5.366GlyPro: 5.366 ± 0.089	2.81GlyGln: 2.81 ± 0.058	7.611GlyArg: 7.611 ± 0.112	5.442GlySer: 5.442 ± 0.084	6.854GlyThr: 6.854 ± 0.114	9.004GlyVal: 9.004 ± 0.113	1.848GlyTrp: 1.848 ± 0.048	2.092GlyTyr: 2.092 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.765HisAla: 2.765 ± 0.061	0.103HisCys: 0.103 ± 0.012	1.467HisAsp: 1.467 ± 0.042	1.338HisGlu: 1.338 ± 0.035	0.396HisPhe: 0.396 ± 0.023	2.311HisGly: 2.311 ± 0.05	0.604HisHis: 0.604 ± 0.024	0.364HisIle: 0.364 ± 0.019	0.245HisLys: 0.245 ± 0.014	2.293HisLeu: 2.293 ± 0.051	0.27HisMet: 0.27 ± 0.017	0.317HisAsn: 0.317 ± 0.019	1.599HisPro: 1.599 ± 0.044	0.575HisGln: 0.575 ± 0.025	1.814HisArg: 1.814 ± 0.04	0.754HisSer: 0.754 ± 0.026	0.983HisThr: 0.983 ± 0.032	2.241HisVal: 2.241 ± 0.046	0.272HisTrp: 0.272 ± 0.017	0.334HisTyr: 0.334 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	3.902IleAla: 3.902 ± 0.071	0.14IleCys: 0.14 ± 0.013	2.106IleAsp: 2.106 ± 0.056	1.795IleGlu: 1.795 ± 0.05	0.671IlePhe: 0.671 ± 0.03	2.703IleGly: 2.703 ± 0.058	0.427IleHis: 0.427 ± 0.024	0.759IleIle: 0.759 ± 0.033	0.522IleLys: 0.522 ± 0.024	2.184IleLeu: 2.184 ± 0.058	0.353IleMet: 0.353 ± 0.019	0.547IleAsn: 0.547 ± 0.025	1.395IlePro: 1.395 ± 0.039	0.601IleGln: 0.601 ± 0.028	1.534IleArg: 1.534 ± 0.042	1.323IleSer: 1.323 ± 0.04	1.961IleThr: 1.961 ± 0.059	2.74IleVal: 2.74 ± 0.062	0.276IleTrp: 0.276 ± 0.019	0.41IleTyr: 0.41 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	2.037LysAla: 2.037 ± 0.063	0.049LysCys: 0.049 ± 0.008	0.937LysAsp: 0.937 ± 0.034	0.844LysGlu: 0.844 ± 0.036	0.299LysPhe: 0.299 ± 0.019	1.324LysGly: 1.324 ± 0.047	0.36LysHis: 0.36 ± 0.019	0.683LysIle: 0.683 ± 0.03	0.516LysLys: 0.516 ± 0.026	1.163LysLeu: 1.163 ± 0.039	0.244LysMet: 0.244 ± 0.018	0.351LysAsn: 0.351 ± 0.018	0.91LysPro: 0.91 ± 0.029	0.503LysGln: 0.503 ± 0.024	1.011LysArg: 1.011 ± 0.037	0.752LysSer: 0.752 ± 0.027	0.907LysThr: 0.907 ± 0.035	1.508LysVal: 1.508 ± 0.045	0.139LysTrp: 0.139 ± 0.012	0.325LysTyr: 0.325 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	16.57LeuAla: 16.57 ± 0.162	0.526LeuCys: 0.526 ± 0.025	6.909LeuAsp: 6.909 ± 0.081	5.415LeuGlu: 5.415 ± 0.083	2.253LeuPhe: 2.253 ± 0.049	9.804LeuGly: 9.804 ± 0.12	2.015LeuHis: 2.015 ± 0.051	1.989LeuIle: 1.989 ± 0.063	1.244LeuLys: 1.244 ± 0.043	10.718LeuLeu: 10.718 ± 0.142	1.359LeuMet: 1.359 ± 0.032	1.273LeuAsn: 1.273 ± 0.04	6.018LeuPro: 6.018 ± 0.088	2.361LeuGln: 2.361 ± 0.046	8.267LeuArg: 8.267 ± 0.101	4.591LeuSer: 4.591 ± 0.07	6.302LeuThr: 6.302 ± 0.085	11.196LeuVal: 11.196 ± 0.136	1.244LeuTrp: 1.244 ± 0.041	1.49LeuTyr: 1.49 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	1.998MetAla: 1.998 ± 0.047	0.092MetCys: 0.092 ± 0.01	0.754MetAsp: 0.754 ± 0.028	0.58MetGlu: 0.58 ± 0.023	0.433MetPhe: 0.433 ± 0.021	1.141MetGly: 1.141 ± 0.035	0.339MetHis: 0.339 ± 0.019	0.553MetIle: 0.553 ± 0.024	0.271MetLys: 0.271 ± 0.016	1.681MetLeu: 1.681 ± 0.047	0.229MetMet: 0.229 ± 0.015	0.356MetAsn: 0.356 ± 0.017	1.077MetPro: 1.077 ± 0.035	0.403MetGln: 0.403 ± 0.02	1.271MetArg: 1.271 ± 0.037	1.282MetSer: 1.282 ± 0.036	1.569MetThr: 1.569 ± 0.04	1.33MetVal: 1.33 ± 0.034	0.18MetTrp: 0.18 ± 0.013	0.241MetTyr: 0.241 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	1.863AsnAla: 1.863 ± 0.05	0.075AsnCys: 0.075 ± 0.009	0.845AsnAsp: 0.845 ± 0.031	0.709AsnGlu: 0.709 ± 0.025	0.374AsnPhe: 0.374 ± 0.02	1.352AsnGly: 1.352 ± 0.05	0.319AsnHis: 0.319 ± 0.019	0.471AsnIle: 0.471 ± 0.021	0.258AsnLys: 0.258 ± 0.018	1.533AsnLeu: 1.533 ± 0.037	0.234AsnMet: 0.234 ± 0.015	0.342AsnAsn: 0.342 ± 0.03	1.216AsnPro: 1.216 ± 0.035	0.435AsnGln: 0.435 ± 0.023	0.959AsnArg: 0.959 ± 0.035	0.563AsnSer: 0.563 ± 0.029	0.812AsnThr: 0.812 ± 0.037	1.465AsnVal: 1.465 ± 0.044	0.159AsnTrp: 0.159 ± 0.013	0.345AsnTyr: 0.345 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	9.877ProAla: 9.877 ± 0.146	0.238ProCys: 0.238 ± 0.017	4.449ProAsp: 4.449 ± 0.073	4.062ProGlu: 4.062 ± 0.073	1.484ProPhe: 1.484 ± 0.043	7.187ProGly: 7.187 ± 0.11	1.219ProHis: 1.219 ± 0.035	1.067ProIle: 1.067 ± 0.03	0.671ProLys: 0.671 ± 0.031	5.111ProLeu: 5.111 ± 0.068	0.85ProMet: 0.85 ± 0.027	0.702ProAsn: 0.702 ± 0.026	3.154ProPro: 3.154 ± 0.091	1.938ProGln: 1.938 ± 0.048	4.181ProArg: 4.181 ± 0.074	3.21ProSer: 3.21 ± 0.067	3.48ProThr: 3.48 ± 0.064	6.133ProVal: 6.133 ± 0.095	0.994ProTrp: 0.994 ± 0.034	1.052ProTyr: 1.052 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	4.22GlnAla: 4.22 ± 0.068	0.121GlnCys: 0.121 ± 0.012	1.472GlnAsp: 1.472 ± 0.036	1.585GlnGlu: 1.585 ± 0.041	0.613GlnPhe: 0.613 ± 0.027	2.476GlnGly: 2.476 ± 0.058	0.705GlnHis: 0.705 ± 0.028	1.006GlnIle: 1.006 ± 0.033	0.383GlnLys: 0.383 ± 0.021	2.723GlnLeu: 2.723 ± 0.062	0.544GlnMet: 0.544 ± 0.022	0.461GlnAsn: 0.461 ± 0.022	1.726GlnPro: 1.726 ± 0.049	1.109GlnGln: 1.109 ± 0.041	2.534GlnArg: 2.534 ± 0.061	1.096GlnSer: 1.096 ± 0.034	1.474GlnThr: 1.474 ± 0.042	3.391GlnVal: 3.391 ± 0.066	0.409GlnTrp: 0.409 ± 0.021	0.537GlnTyr: 0.537 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	10.613ArgAla: 10.613 ± 0.152	0.376ArgCys: 0.376 ± 0.022	4.218ArgAsp: 4.218 ± 0.064	4.699ArgGlu: 4.699 ± 0.071	2.07ArgPhe: 2.07 ± 0.051	5.929ArgGly: 5.929 ± 0.078	1.78ArgHis: 1.78 ± 0.044	2.296ArgIle: 2.296 ± 0.054	1.238ArgLys: 1.238 ± 0.04	8.263ArgLeu: 8.263 ± 0.108	1.598ArgMet: 1.598 ± 0.041	1.033ArgAsn: 1.033 ± 0.034	4.889ArgPro: 4.889 ± 0.08	2.217ArgGln: 2.217 ± 0.062	7.985ArgArg: 7.985 ± 0.134	4.145ArgSer: 4.145 ± 0.074	5.2ArgThr: 5.2 ± 0.083	7.016ArgVal: 7.016 ± 0.086	1.575ArgTrp: 1.575 ± 0.041	1.65ArgTyr: 1.65 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	6.504SerAla: 6.504 ± 0.083	0.258SerCys: 0.258 ± 0.017	2.499SerAsp: 2.499 ± 0.049	2.1SerGlu: 2.1 ± 0.05	1.419SerPhe: 1.419 ± 0.039	5.404SerGly: 5.404 ± 0.084	0.909SerHis: 0.909 ± 0.028	1.365SerIle: 1.365 ± 0.045	0.742SerLys: 0.742 ± 0.032	4.608SerLeu: 4.608 ± 0.072	0.934SerMet: 0.934 ± 0.033	0.768SerAsn: 0.768 ± 0.031	3.075SerPro: 3.075 ± 0.055	1.304SerGln: 1.304 ± 0.043	3.644SerArg: 3.644 ± 0.068	2.753SerSer: 2.753 ± 0.061	3.506SerThr: 3.506 ± 0.071	4.434SerVal: 4.434 ± 0.074	0.831SerTrp: 0.831 ± 0.03	1.006SerTyr: 1.006 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	8.816ThrAla: 8.816 ± 0.122	0.324ThrCys: 0.324 ± 0.031	3.525ThrAsp: 3.525 ± 0.064	2.955ThrGlu: 2.955 ± 0.059	1.871ThrPhe: 1.871 ± 0.058	6.465ThrGly: 6.465 ± 0.086	1.157ThrHis: 1.157 ± 0.032	1.766ThrIle: 1.766 ± 0.046	0.884ThrLys: 0.884 ± 0.036	5.927ThrLeu: 5.927 ± 0.069	0.87ThrMet: 0.87 ± 0.03	0.901ThrAsn: 0.901 ± 0.042	4.243ThrPro: 4.243 ± 0.075	1.475ThrGln: 1.475 ± 0.042	3.787ThrArg: 3.787 ± 0.07	3.343ThrSer: 3.343 ± 0.061	4.57ThrThr: 4.57 ± 0.084	6.834ThrVal: 6.834 ± 0.141	1.043ThrTrp: 1.043 ± 0.036	1.31ThrTyr: 1.31 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	14.858ValAla: 14.858 ± 0.162	0.589ValCys: 0.589 ± 0.025	6.323ValAsp: 6.323 ± 0.082	6.032ValGlu: 6.032 ± 0.074	2.211ValPhe: 2.211 ± 0.053	8.647ValGly: 8.647 ± 0.115	2.01ValHis: 2.01 ± 0.051	2.604ValIle: 2.604 ± 0.059	1.292ValLys: 1.292 ± 0.046	11.467ValLeu: 11.467 ± 0.135	1.507ValMet: 1.507 ± 0.042	1.469ValAsn: 1.469 ± 0.043	6.389ValPro: 6.389 ± 0.085	2.424ValGln: 2.424 ± 0.053	8.198ValArg: 8.198 ± 0.112	4.603ValSer: 4.603 ± 0.066	6.832ValThr: 6.832 ± 0.123	12.94ValVal: 12.94 ± 0.159	1.268ValTrp: 1.268 ± 0.039	1.507ValTyr: 1.507 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.826TrpAla: 1.826 ± 0.052	0.126TrpCys: 0.126 ± 0.011	0.921TrpAsp: 0.921 ± 0.031	0.725TrpGlu: 0.725 ± 0.028	0.538TrpPhe: 0.538 ± 0.024	1.139TrpGly: 1.139 ± 0.041	0.335TrpHis: 0.335 ± 0.018	0.441TrpIle: 0.441 ± 0.018	0.241TrpLys: 0.241 ± 0.017	1.694TrpLeu: 1.694 ± 0.047	0.269TrpMet: 0.269 ± 0.019	0.319TrpAsn: 0.319 ± 0.018	0.749TrpPro: 0.749 ± 0.026	0.568TrpGln: 0.568 ± 0.023	1.271TrpArg: 1.271 ± 0.043	0.916TrpSer: 0.916 ± 0.03	1.002TrpThr: 1.002 ± 0.03	1.351TrpVal: 1.351 ± 0.035	0.43TrpTrp: 0.43 ± 0.025	0.307TrpTyr: 0.307 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.304TyrAla: 2.304 ± 0.049	0.111TyrCys: 0.111 ± 0.01	1.264TyrAsp: 1.264 ± 0.04	1.093TyrGlu: 1.093 ± 0.035	0.512TyrPhe: 0.512 ± 0.023	1.767TyrGly: 1.767 ± 0.046	0.306TyrHis: 0.306 ± 0.016	0.321TyrIle: 0.321 ± 0.021	0.277TyrLys: 0.277 ± 0.018	1.96TyrLeu: 1.96 ± 0.042	0.213TyrMet: 0.213 ± 0.015	0.306TyrAsn: 0.306 ± 0.017	0.975TyrPro: 0.975 ± 0.033	0.553TyrGln: 0.553 ± 0.024	1.552TyrArg: 1.552 ± 0.04	0.871TyrSer: 0.871 ± 0.032	1.013TyrThr: 1.013 ± 0.035	1.77TyrVal: 1.77 ± 0.042	0.291TyrTrp: 0.291 ± 0.017	0.378TyrTyr: 0.378 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3108 proteins (1032422 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---