Amino acid dipepetide frequency for Cow vetch latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.943AlaAla: 3.943 ± 1.067
1.577AlaCys: 1.577 ± 1.009
1.577AlaAsp: 1.577 ± 0.835
2.366AlaGlu: 2.366 ± 0.961
3.943AlaPhe: 3.943 ± 1.872
2.366AlaGly: 2.366 ± 1.508
1.577AlaHis: 1.577 ± 0.835
0.0AlaIle: 0.0 ± 0.0
0.789AlaLys: 0.789 ± 0.672
3.155AlaLeu: 3.155 ± 1.536
1.577AlaMet: 1.577 ± 1.345
2.366AlaAsn: 2.366 ± 0.997
0.0AlaPro: 0.0 ± 0.0
0.0AlaGln: 0.0 ± 0.0
2.366AlaArg: 2.366 ± 1.483
1.577AlaSer: 1.577 ± 1.048
1.577AlaThr: 1.577 ± 0.856
2.366AlaVal: 2.366 ± 1.48
0.789AlaTrp: 0.789 ± 0.849
1.577AlaTyr: 1.577 ± 0.827
0.0AlaXaa: 0.0 ± 0.0
Cys
0.789CysAla: 0.789 ± 0.849
1.577CysCys: 1.577 ± 0.856
3.155CysAsp: 3.155 ± 2.287
1.577CysGlu: 1.577 ± 0.831
1.577CysPhe: 1.577 ± 1.004
0.789CysGly: 0.789 ± 0.695
0.0CysHis: 0.0 ± 0.0
2.366CysIle: 2.366 ± 1.771
1.577CysLys: 1.577 ± 0.948
1.577CysLeu: 1.577 ± 0.948
0.0CysMet: 0.0 ± 0.0
2.366CysAsn: 2.366 ± 1.427
0.0CysPro: 0.0 ± 0.0
0.789CysGln: 0.789 ± 0.655
2.366CysArg: 2.366 ± 1.149
3.155CysSer: 3.155 ± 1.844
3.155CysThr: 3.155 ± 1.37
0.789CysVal: 0.789 ± 0.709
0.789CysTrp: 0.789 ± 0.672
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.732AspAla: 4.732 ± 1.223
2.366AspCys: 2.366 ± 1.373
3.943AspAsp: 3.943 ± 1.565
1.577AspGlu: 1.577 ± 1.037
1.577AspPhe: 1.577 ± 0.856
1.577AspGly: 1.577 ± 1.037
0.789AspHis: 0.789 ± 0.672
5.521AspIle: 5.521 ± 1.495
3.155AspLys: 3.155 ± 1.356
2.366AspLeu: 2.366 ± 2.086
4.732AspMet: 4.732 ± 1.174
1.577AspAsn: 1.577 ± 1.516
0.789AspPro: 0.789 ± 0.849
2.366AspGln: 2.366 ± 1.005
1.577AspArg: 1.577 ± 1.345
3.943AspSer: 3.943 ± 1.069
1.577AspThr: 1.577 ± 1.004
6.309AspVal: 6.309 ± 2.572
0.789AspTrp: 0.789 ± 0.792
3.943AspTyr: 3.943 ± 1.859
0.0AspXaa: 0.0 ± 0.0
Glu
2.366GluAla: 2.366 ± 1.117
0.0GluCys: 0.0 ± 0.0
13.407GluAsp: 13.407 ± 2.079
9.464GluGlu: 9.464 ± 4.222
3.155GluPhe: 3.155 ± 1.824
1.577GluGly: 1.577 ± 1.345
1.577GluHis: 1.577 ± 0.831
3.155GluIle: 3.155 ± 1.07
2.366GluLys: 2.366 ± 0.947
6.309GluLeu: 6.309 ± 1.811
0.789GluMet: 0.789 ± 0.672
1.577GluAsn: 1.577 ± 1.037
0.0GluPro: 0.0 ± 0.0
3.943GluGln: 3.943 ± 1.672
2.366GluArg: 2.366 ± 1.731
5.521GluSer: 5.521 ± 0.995
2.366GluThr: 2.366 ± 0.943
3.943GluVal: 3.943 ± 1.118
0.789GluTrp: 0.789 ± 0.764
1.577GluTyr: 1.577 ± 1.345
0.0GluXaa: 0.0 ± 0.0
Phe
1.577PheAla: 1.577 ± 0.835
1.577PheCys: 1.577 ± 0.95
1.577PheAsp: 1.577 ± 0.827
2.366PheGlu: 2.366 ± 1.483
0.789PhePhe: 0.789 ± 0.709
0.789PheGly: 0.789 ± 0.672
0.0PheHis: 0.0 ± 0.0
3.155PheIle: 3.155 ± 1.688
0.789PheLys: 0.789 ± 0.655
5.521PheLeu: 5.521 ± 2.488
0.0PheMet: 0.0 ± 0.0
1.577PheAsn: 1.577 ± 1.529
2.366PhePro: 2.366 ± 1.019
3.155PheGln: 3.155 ± 1.0
3.155PheArg: 3.155 ± 1.453
5.521PheSer: 5.521 ± 1.226
1.577PheThr: 1.577 ± 1.345
3.155PheVal: 3.155 ± 1.658
0.789PheTrp: 0.789 ± 0.792
1.577PheTyr: 1.577 ± 0.856
0.0PheXaa: 0.0 ± 0.0
Gly
3.155GlyAla: 3.155 ± 0.914
2.366GlyCys: 2.366 ± 0.983
0.789GlyAsp: 0.789 ± 0.792
5.521GlyGlu: 5.521 ± 2.551
2.366GlyPhe: 2.366 ± 1.16
4.732GlyGly: 4.732 ± 1.624
0.0GlyHis: 0.0 ± 0.0
3.943GlyIle: 3.943 ± 0.987
5.521GlyLys: 5.521 ± 2.588
3.943GlyLeu: 3.943 ± 2.17
3.155GlyMet: 3.155 ± 0.96
1.577GlyAsn: 1.577 ± 0.726
3.155GlyPro: 3.155 ± 1.389
2.366GlyGln: 2.366 ± 1.684
3.155GlyArg: 3.155 ± 2.11
4.732GlySer: 4.732 ± 1.783
0.789GlyThr: 0.789 ± 0.672
5.521GlyVal: 5.521 ± 1.761
0.0GlyTrp: 0.0 ± 0.0
4.732GlyTyr: 4.732 ± 1.414
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.789HisAsp: 0.789 ± 0.709
2.366HisGlu: 2.366 ± 0.907
1.577HisPhe: 1.577 ± 1.345
0.789HisGly: 0.789 ± 0.792
0.0HisHis: 0.0 ± 0.0
0.789HisIle: 0.789 ± 0.695
0.789HisLys: 0.789 ± 0.758
3.943HisLeu: 3.943 ± 1.399
0.0HisMet: 0.0 ± 0.0
1.577HisAsn: 1.577 ± 1.529
0.0HisPro: 0.0 ± 0.0
0.789HisGln: 0.789 ± 0.672
0.789HisArg: 0.789 ± 0.655
1.577HisSer: 1.577 ± 1.31
0.0HisThr: 0.0 ± 0.0
0.789HisVal: 0.789 ± 0.764
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.155IleAla: 3.155 ± 1.912
2.366IleCys: 2.366 ± 1.48
0.0IleAsp: 0.0 ± 0.0
5.521IleGlu: 5.521 ± 2.423
1.577IlePhe: 1.577 ± 1.133
5.521IleGly: 5.521 ± 2.151
1.577IleHis: 1.577 ± 0.904
3.943IleIle: 3.943 ± 1.343
3.155IleLys: 3.155 ± 1.043
6.309IleLeu: 6.309 ± 1.369
3.155IleMet: 3.155 ± 1.771
0.789IleAsn: 0.789 ± 0.709
1.577IlePro: 1.577 ± 1.004
2.366IleGln: 2.366 ± 0.993
2.366IleArg: 2.366 ± 0.988
2.366IleSer: 2.366 ± 1.478
3.943IleThr: 3.943 ± 2.698
7.098IleVal: 7.098 ± 1.988
1.577IleTrp: 1.577 ± 0.856
0.789IleTyr: 0.789 ± 0.709
0.0IleXaa: 0.0 ± 0.0
Lys
1.577LysAla: 1.577 ± 0.95
0.789LysCys: 0.789 ± 0.655
4.732LysAsp: 4.732 ± 2.035
5.521LysGlu: 5.521 ± 2.244
2.366LysPhe: 2.366 ± 1.149
1.577LysGly: 1.577 ± 1.31
0.789LysHis: 0.789 ± 0.672
2.366LysIle: 2.366 ± 0.988
5.521LysLys: 5.521 ± 1.55
3.943LysLeu: 3.943 ± 1.221
1.577LysMet: 1.577 ± 0.896
3.155LysAsn: 3.155 ± 1.67
1.577LysPro: 1.577 ± 0.86
0.789LysGln: 0.789 ± 0.709
6.309LysArg: 6.309 ± 2.519
3.943LysSer: 3.943 ± 1.762
4.732LysThr: 4.732 ± 1.762
5.521LysVal: 5.521 ± 2.178
0.789LysTrp: 0.789 ± 0.655
4.732LysTyr: 4.732 ± 1.745
0.0LysXaa: 0.0 ± 0.0
Leu
1.577LeuAla: 1.577 ± 1.037
0.789LeuCys: 0.789 ± 0.709
5.521LeuAsp: 5.521 ± 2.895
3.155LeuGlu: 3.155 ± 0.999
3.155LeuPhe: 3.155 ± 1.07
7.098LeuGly: 7.098 ± 2.304
3.155LeuHis: 3.155 ± 1.044
3.943LeuIle: 3.943 ± 1.493
8.675LeuLys: 8.675 ± 3.233
16.562LeuLeu: 16.562 ± 4.201
2.366LeuMet: 2.366 ± 1.301
9.464LeuAsn: 9.464 ± 3.305
4.732LeuPro: 4.732 ± 2.653
3.155LeuGln: 3.155 ± 1.0
5.521LeuArg: 5.521 ± 1.555
5.521LeuSer: 5.521 ± 1.307
2.366LeuThr: 2.366 ± 1.153
10.252LeuVal: 10.252 ± 2.233
1.577LeuTrp: 1.577 ± 1.046
5.521LeuTyr: 5.521 ± 1.706
0.0LeuXaa: 0.0 ± 0.0
Met
2.366MetAla: 2.366 ± 1.478
1.577MetCys: 1.577 ± 1.009
1.577MetAsp: 1.577 ± 0.904
3.943MetGlu: 3.943 ± 1.493
1.577MetPhe: 1.577 ± 0.835
0.789MetGly: 0.789 ± 0.792
0.0MetHis: 0.0 ± 0.0
2.366MetIle: 2.366 ± 1.162
10.252MetLys: 10.252 ± 2.526
3.155MetLeu: 3.155 ± 1.242
0.789MetMet: 0.789 ± 0.764
0.789MetAsn: 0.789 ± 0.709
0.789MetPro: 0.789 ± 0.655
0.789MetGln: 0.789 ± 0.672
1.577MetArg: 1.577 ± 0.896
0.789MetSer: 0.789 ± 0.792
0.0MetThr: 0.0 ± 0.0
4.732MetVal: 4.732 ± 1.872
0.0MetTrp: 0.0 ± 0.0
0.789MetTyr: 0.789 ± 0.655
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.789AsnCys: 0.789 ± 0.695
1.577AsnAsp: 1.577 ± 1.529
1.577AsnGlu: 1.577 ± 1.083
1.577AsnPhe: 1.577 ± 0.827
3.155AsnGly: 3.155 ± 1.508
0.0AsnHis: 0.0 ± 0.0
3.155AsnIle: 3.155 ± 2.137
0.789AsnLys: 0.789 ± 0.655
3.155AsnLeu: 3.155 ± 2.166
1.577AsnMet: 1.577 ± 0.938
0.789AsnAsn: 0.789 ± 0.672
3.943AsnPro: 3.943 ± 1.716
0.789AsnGln: 0.789 ± 0.709
2.366AsnArg: 2.366 ± 1.8
1.577AsnSer: 1.577 ± 1.128
3.155AsnThr: 3.155 ± 1.808
1.577AsnVal: 1.577 ± 1.083
2.366AsnTrp: 2.366 ± 1.583
3.943AsnTyr: 3.943 ± 1.777
0.0AsnXaa: 0.0 ± 0.0
Pro
0.789ProAla: 0.789 ± 0.655
0.0ProCys: 0.0 ± 0.0
1.577ProAsp: 1.577 ± 1.004
1.577ProGlu: 1.577 ± 1.009
2.366ProPhe: 2.366 ± 1.196
3.943ProGly: 3.943 ± 1.089
0.0ProHis: 0.0 ± 0.0
3.155ProIle: 3.155 ± 1.407
1.577ProLys: 1.577 ± 1.022
4.732ProLeu: 4.732 ± 1.734
0.789ProMet: 0.789 ± 0.695
0.0ProAsn: 0.0 ± 0.0
1.577ProPro: 1.577 ± 1.088
1.577ProGln: 1.577 ± 1.133
3.155ProArg: 3.155 ± 1.156
2.366ProSer: 2.366 ± 1.341
1.577ProThr: 1.577 ± 1.022
1.577ProVal: 1.577 ± 1.698
1.577ProTrp: 1.577 ± 1.345
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.366GlnAla: 2.366 ± 1.117
0.789GlnCys: 0.789 ± 0.792
4.732GlnAsp: 4.732 ± 1.699
0.789GlnGlu: 0.789 ± 0.764
0.789GlnPhe: 0.789 ± 0.709
5.521GlnGly: 5.521 ± 1.853
1.577GlnHis: 1.577 ± 0.831
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
5.521GlnLeu: 5.521 ± 1.834
0.0GlnMet: 0.0 ± 0.0
1.577GlnAsn: 1.577 ± 1.584
2.366GlnPro: 2.366 ± 1.283
1.577GlnGln: 1.577 ± 0.955
2.366GlnArg: 2.366 ± 1.283
2.366GlnSer: 2.366 ± 1.427
0.789GlnThr: 0.789 ± 0.655
2.366GlnVal: 2.366 ± 1.427
0.0GlnTrp: 0.0 ± 0.0
2.366GlnTyr: 2.366 ± 1.341
0.0GlnXaa: 0.0 ± 0.0
Arg
1.577ArgAla: 1.577 ± 1.345
0.789ArgCys: 0.789 ± 0.695
2.366ArgAsp: 2.366 ± 1.253
5.521ArgGlu: 5.521 ± 1.671
1.577ArgPhe: 1.577 ± 0.935
3.155ArgGly: 3.155 ± 1.303
1.577ArgHis: 1.577 ± 1.022
3.943ArgIle: 3.943 ± 1.806
6.309ArgLys: 6.309 ± 1.799
5.521ArgLeu: 5.521 ± 2.376
3.155ArgMet: 3.155 ± 1.529
1.577ArgAsn: 1.577 ± 1.019
3.155ArgPro: 3.155 ± 1.294
3.943ArgGln: 3.943 ± 1.516
9.464ArgArg: 9.464 ± 2.134
4.732ArgSer: 4.732 ± 1.864
0.789ArgThr: 0.789 ± 0.849
3.155ArgVal: 3.155 ± 1.585
1.577ArgTrp: 1.577 ± 0.726
3.155ArgTyr: 3.155 ± 1.177
0.0ArgXaa: 0.0 ± 0.0
Ser
0.789SerAla: 0.789 ± 0.672
2.366SerCys: 2.366 ± 1.341
1.577SerAsp: 1.577 ± 0.935
3.943SerGlu: 3.943 ± 0.985
6.309SerPhe: 6.309 ± 1.804
7.098SerGly: 7.098 ± 2.832
0.789SerHis: 0.789 ± 0.792
1.577SerIle: 1.577 ± 0.904
0.789SerLys: 0.789 ± 0.695
6.309SerLeu: 6.309 ± 1.677
4.732SerMet: 4.732 ± 0.868
3.943SerAsn: 3.943 ± 1.918
3.943SerPro: 3.943 ± 1.354
0.789SerGln: 0.789 ± 0.764
6.309SerArg: 6.309 ± 1.507
11.041SerSer: 11.041 ± 4.169
1.577SerThr: 1.577 ± 1.088
5.521SerVal: 5.521 ± 1.293
0.0SerTrp: 0.0 ± 0.0
1.577SerTyr: 1.577 ± 0.827
0.0SerXaa: 0.0 ± 0.0
Thr
1.577ThrAla: 1.577 ± 0.86
3.155ThrCys: 3.155 ± 1.473
1.577ThrAsp: 1.577 ± 1.391
0.0ThrGlu: 0.0 ± 0.0
0.0ThrPhe: 0.0 ± 0.0
2.366ThrGly: 2.366 ± 1.483
0.789ThrHis: 0.789 ± 0.764
3.155ThrIle: 3.155 ± 1.07
1.577ThrLys: 1.577 ± 1.022
5.521ThrLeu: 5.521 ± 2.194
1.577ThrMet: 1.577 ± 0.997
0.0ThrAsn: 0.0 ± 0.0
2.366ThrPro: 2.366 ± 1.012
2.366ThrGln: 2.366 ± 1.373
3.155ThrArg: 3.155 ± 1.049
1.577ThrSer: 1.577 ± 0.86
3.155ThrThr: 3.155 ± 1.489
2.366ThrVal: 2.366 ± 0.77
1.577ThrTrp: 1.577 ± 0.904
1.577ThrTyr: 1.577 ± 0.726
0.0ThrXaa: 0.0 ± 0.0
Val
1.577ValAla: 1.577 ± 1.088
3.155ValCys: 3.155 ± 1.736
2.366ValAsp: 2.366 ± 1.026
5.521ValGlu: 5.521 ± 1.965
2.366ValPhe: 2.366 ± 1.195
3.155ValGly: 3.155 ± 1.872
1.577ValHis: 1.577 ± 0.876
7.886ValIle: 7.886 ± 2.602
7.098ValLys: 7.098 ± 2.206
10.252ValLeu: 10.252 ± 2.519
6.309ValMet: 6.309 ± 1.028
3.155ValAsn: 3.155 ± 0.915
0.789ValPro: 0.789 ± 0.655
2.366ValGln: 2.366 ± 1.414
4.732ValArg: 4.732 ± 1.835
6.309ValSer: 6.309 ± 2.065
3.943ValThr: 3.943 ± 1.514
10.252ValVal: 10.252 ± 3.463
0.0ValTrp: 0.0 ± 0.0
3.943ValTyr: 3.943 ± 1.825
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.577TrpCys: 1.577 ± 0.856
1.577TrpAsp: 1.577 ± 1.004
2.366TrpGlu: 2.366 ± 1.313
0.789TrpPhe: 0.789 ± 0.764
0.789TrpGly: 0.789 ± 0.655
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.789TrpLys: 0.789 ± 0.695
1.577TrpLeu: 1.577 ± 1.114
0.789TrpMet: 0.789 ± 0.672
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.789TrpArg: 0.789 ± 0.655
0.789TrpSer: 0.789 ± 0.655
0.0TrpThr: 0.0 ± 0.0
3.155TrpVal: 3.155 ± 1.07
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.577TyrAla: 1.577 ± 1.345
0.789TyrCys: 0.789 ± 0.672
0.789TyrAsp: 0.789 ± 0.672
1.577TyrGlu: 1.577 ± 1.391
1.577TyrPhe: 1.577 ± 1.037
4.732TyrGly: 4.732 ± 1.62
0.789TyrHis: 0.789 ± 0.764
4.732TyrIle: 4.732 ± 1.434
0.789TyrLys: 0.789 ± 0.655
4.732TyrLeu: 4.732 ± 1.355
0.789TyrMet: 0.789 ± 0.665
0.0TyrAsn: 0.0 ± 0.0
0.789TyrPro: 0.789 ± 0.792
3.943TyrGln: 3.943 ± 1.911
3.155TyrArg: 3.155 ± 2.115
1.577TyrSer: 1.577 ± 1.065
3.155TyrThr: 3.155 ± 1.299
6.309TyrVal: 6.309 ± 1.573
0.0TyrTrp: 0.0 ± 0.0
0.789TyrTyr: 0.789 ± 0.849
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1269 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski