Amino acid dipepetide frequency for Boudabousia liubingyangii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.915AlaAla: 13.915 ± 0.24	0.909AlaCys: 0.909 ± 0.043	5.767AlaAsp: 5.767 ± 0.089	7.315AlaGlu: 7.315 ± 0.14	3.644AlaPhe: 3.644 ± 0.08	9.013AlaGly: 9.013 ± 0.148	1.956AlaHis: 1.956 ± 0.061	5.073AlaIle: 5.073 ± 0.106	5.107AlaLys: 5.107 ± 0.12	11.988AlaLeu: 11.988 ± 0.193	2.365AlaMet: 2.365 ± 0.072	3.305AlaAsn: 3.305 ± 0.069	5.546AlaPro: 5.546 ± 0.172	5.75AlaGln: 5.75 ± 0.135	5.926AlaArg: 5.926 ± 0.114	5.789AlaSer: 5.789 ± 0.101	6.084AlaThr: 6.084 ± 0.121	7.169AlaVal: 7.169 ± 0.122	1.539AlaTrp: 1.539 ± 0.056	2.478AlaTyr: 2.478 ± 0.066	0.0AlaXaa: 0.0 ± 0.0
Cys	0.884CysAla: 0.884 ± 0.039	0.075CysCys: 0.075 ± 0.011	0.436CysAsp: 0.436 ± 0.029	0.526CysGlu: 0.526 ± 0.036	0.286CysPhe: 0.286 ± 0.023	0.768CysGly: 0.768 ± 0.037	0.123CysHis: 0.123 ± 0.017	0.269CysIle: 0.269 ± 0.021	0.163CysLys: 0.163 ± 0.014	0.727CysLeu: 0.727 ± 0.038	0.106CysMet: 0.106 ± 0.014	0.225CysAsn: 0.225 ± 0.023	0.453CysPro: 0.453 ± 0.029	0.344CysGln: 0.344 ± 0.025	0.376CysArg: 0.376 ± 0.026	0.477CysSer: 0.477 ± 0.025	0.381CysThr: 0.381 ± 0.026	0.535CysVal: 0.535 ± 0.032	0.094CysTrp: 0.094 ± 0.013	0.208CysTyr: 0.208 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	5.088AspAla: 5.088 ± 0.106	0.366AspCys: 0.366 ± 0.024	2.609AspAsp: 2.609 ± 0.084	3.683AspGlu: 3.683 ± 0.095	2.319AspPhe: 2.319 ± 0.053	4.345AspGly: 4.345 ± 0.1	1.027AspHis: 1.027 ± 0.042	2.234AspIle: 2.234 ± 0.061	1.75AspLys: 1.75 ± 0.049	6.43AspLeu: 6.43 ± 0.108	0.977AspMet: 0.977 ± 0.043	1.401AspAsn: 1.401 ± 0.056	3.845AspPro: 3.845 ± 0.084	2.501AspGln: 2.501 ± 0.061	3.022AspArg: 3.022 ± 0.074	2.917AspSer: 2.917 ± 0.082	2.406AspThr: 2.406 ± 0.074	3.344AspVal: 3.344 ± 0.09	0.889AspTrp: 0.889 ± 0.042	1.732AspTyr: 1.732 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	7.678GluAla: 7.678 ± 0.163	0.392GluCys: 0.392 ± 0.028	3.487GluAsp: 3.487 ± 0.083	4.499GluGlu: 4.499 ± 0.102	1.79GluPhe: 1.79 ± 0.056	4.62GluGly: 4.62 ± 0.11	1.376GluHis: 1.376 ± 0.054	3.436GluIle: 3.436 ± 0.089	3.162GluLys: 3.162 ± 0.088	7.358GluLeu: 7.358 ± 0.152	1.294GluMet: 1.294 ± 0.047	2.403GluAsn: 2.403 ± 0.074	3.031GluPro: 3.031 ± 0.096	2.75GluGln: 2.75 ± 0.069	3.622GluArg: 3.622 ± 0.092	3.237GluSer: 3.237 ± 0.084	3.467GluThr: 3.467 ± 0.096	5.187GluVal: 5.187 ± 0.111	0.669GluTrp: 0.669 ± 0.032	1.485GluTyr: 1.485 ± 0.05	0.0GluXaa: 0.0 ± 0.0
Phe	3.503PheAla: 3.503 ± 0.087	0.303PheCys: 0.303 ± 0.025	2.132PheAsp: 2.132 ± 0.061	2.287PheGlu: 2.287 ± 0.073	1.534PhePhe: 1.534 ± 0.054	3.138PheGly: 3.138 ± 0.088	0.608PheHis: 0.608 ± 0.032	1.618PheIle: 1.618 ± 0.061	1.469PheLys: 1.469 ± 0.049	3.395PheLeu: 3.395 ± 0.087	0.744PheMet: 0.744 ± 0.039	1.243PheAsn: 1.243 ± 0.048	1.584PhePro: 1.584 ± 0.052	1.231PheGln: 1.231 ± 0.044	1.58PheArg: 1.58 ± 0.06	2.323PheSer: 2.323 ± 0.061	2.275PheThr: 2.275 ± 0.07	2.598PheVal: 2.598 ± 0.072	0.604PheTrp: 0.604 ± 0.041	0.909PheTyr: 0.909 ± 0.043	0.0PheXaa: 0.0 ± 0.0
Gly	8.09GlyAla: 8.09 ± 0.147	0.579GlyCys: 0.579 ± 0.034	3.763GlyAsp: 3.763 ± 0.09	4.327GlyGlu: 4.327 ± 0.109	3.053GlyPhe: 3.053 ± 0.08	6.028GlyGly: 6.028 ± 0.143	1.65GlyHis: 1.65 ± 0.075	4.565GlyIle: 4.565 ± 0.094	4.156GlyLys: 4.156 ± 0.09	7.697GlyLeu: 7.697 ± 0.13	1.979GlyMet: 1.979 ± 0.059	2.319GlyAsn: 2.319 ± 0.065	3.417GlyPro: 3.417 ± 0.085	3.635GlyGln: 3.635 ± 0.097	4.495GlyArg: 4.495 ± 0.105	4.703GlySer: 4.703 ± 0.087	4.831GlyThr: 4.831 ± 0.107	5.929GlyVal: 5.929 ± 0.111	1.262GlyTrp: 1.262 ± 0.051	2.282GlyTyr: 2.282 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	1.8HisAla: 1.8 ± 0.052	0.191HisCys: 0.191 ± 0.016	1.071HisAsp: 1.071 ± 0.043	1.177HisGlu: 1.177 ± 0.046	0.679HisPhe: 0.679 ± 0.033	1.469HisGly: 1.469 ± 0.051	0.513HisHis: 0.513 ± 0.033	0.741HisIle: 0.741 ± 0.037	0.524HisLys: 0.524 ± 0.029	2.265HisLeu: 2.265 ± 0.07	0.334HisMet: 0.334 ± 0.023	0.533HisAsn: 0.533 ± 0.029	1.456HisPro: 1.456 ± 0.054	0.86HisGln: 0.86 ± 0.031	1.102HisArg: 1.102 ± 0.044	0.948HisSer: 0.948 ± 0.043	0.96HisThr: 0.96 ± 0.04	1.308HisVal: 1.308 ± 0.053	0.341HisTrp: 0.341 ± 0.022	0.547HisTyr: 0.547 ± 0.034	0.0HisXaa: 0.0 ± 0.0
Ile	5.582IleAla: 5.582 ± 0.103	0.485IleCys: 0.485 ± 0.031	3.019IleAsp: 3.019 ± 0.084	3.056IleGlu: 3.056 ± 0.079	1.88IlePhe: 1.88 ± 0.064	3.971IleGly: 3.971 ± 0.108	0.853IleHis: 0.853 ± 0.036	2.84IleIle: 2.84 ± 0.103	1.984IleLys: 1.984 ± 0.066	4.887IleLeu: 4.887 ± 0.116	1.078IleMet: 1.078 ± 0.043	1.819IleAsn: 1.819 ± 0.059	3.016IlePro: 3.016 ± 0.069	1.464IleGln: 1.464 ± 0.049	2.588IleArg: 2.588 ± 0.061	3.331IleSer: 3.331 ± 0.09	3.07IleThr: 3.07 ± 0.078	3.715IleVal: 3.715 ± 0.096	0.737IleTrp: 0.737 ± 0.034	1.301IleTyr: 1.301 ± 0.048	0.0IleXaa: 0.0 ± 0.0
Lys	4.844LysAla: 4.844 ± 0.106	0.218LysCys: 0.218 ± 0.018	2.534LysAsp: 2.534 ± 0.07	2.798LysGlu: 2.798 ± 0.076	1.165LysPhe: 1.165 ± 0.046	2.697LysGly: 2.697 ± 0.082	0.833LysHis: 0.833 ± 0.04	2.193LysIle: 2.193 ± 0.066	2.062LysLys: 2.062 ± 0.078	4.129LysLeu: 4.129 ± 0.103	0.981LysMet: 0.981 ± 0.038	1.737LysAsn: 1.737 ± 0.061	2.476LysPro: 2.476 ± 0.111	1.934LysGln: 1.934 ± 0.062	2.525LysArg: 2.525 ± 0.07	2.5LysSer: 2.5 ± 0.081	2.81LysThr: 2.81 ± 0.071	3.252LysVal: 3.252 ± 0.095	0.497LysTrp: 0.497 ± 0.03	1.17LysTyr: 1.17 ± 0.055	0.0LysXaa: 0.0 ± 0.0
Leu	12.318LeuAla: 12.318 ± 0.195	0.712LeuCys: 0.712 ± 0.041	5.706LeuAsp: 5.706 ± 0.101	6.471LeuGlu: 6.471 ± 0.136	3.2LeuPhe: 3.2 ± 0.082	8.759LeuGly: 8.759 ± 0.158	1.81LeuHis: 1.81 ± 0.065	5.456LeuIle: 5.456 ± 0.13	4.586LeuLys: 4.586 ± 0.086	10.237LeuLeu: 10.237 ± 0.192	2.123LeuMet: 2.123 ± 0.063	3.29LeuAsn: 3.29 ± 0.094	5.921LeuPro: 5.921 ± 0.1	3.189LeuGln: 3.189 ± 0.082	5.464LeuArg: 5.464 ± 0.121	6.677LeuSer: 6.677 ± 0.147	6.118LeuThr: 6.118 ± 0.111	8.097LeuVal: 8.097 ± 0.14	1.33LeuTrp: 1.33 ± 0.056	2.038LeuTyr: 2.038 ± 0.058	0.0LeuXaa: 0.0 ± 0.0
Met	2.333MetAla: 2.333 ± 0.066	0.124MetCys: 0.124 ± 0.013	1.052MetAsp: 1.052 ± 0.047	1.081MetGlu: 1.081 ± 0.043	0.685MetPhe: 0.685 ± 0.039	1.635MetGly: 1.635 ± 0.052	0.373MetHis: 0.373 ± 0.022	1.172MetIle: 1.172 ± 0.05	0.845MetLys: 0.845 ± 0.039	2.14MetLeu: 2.14 ± 0.074	0.502MetMet: 0.502 ± 0.038	0.737MetAsn: 0.737 ± 0.035	1.212MetPro: 1.212 ± 0.05	0.635MetGln: 0.635 ± 0.034	1.279MetArg: 1.279 ± 0.047	1.536MetSer: 1.536 ± 0.048	1.403MetThr: 1.403 ± 0.057	1.556MetVal: 1.556 ± 0.063	0.221MetTrp: 0.221 ± 0.019	0.421MetTyr: 0.421 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.072AsnAla: 3.072 ± 0.075	0.255AsnCys: 0.255 ± 0.019	1.623AsnAsp: 1.623 ± 0.054	1.909AsnGlu: 1.909 ± 0.065	1.148AsnPhe: 1.148 ± 0.049	2.578AsnGly: 2.578 ± 0.075	0.678AsnHis: 0.678 ± 0.031	1.396AsnIle: 1.396 ± 0.053	1.074AsnLys: 1.074 ± 0.046	3.646AsnLeu: 3.646 ± 0.089	0.637AsnMet: 0.637 ± 0.039	1.027AsnAsn: 1.027 ± 0.053	2.515AsnPro: 2.515 ± 0.086	1.64AsnGln: 1.64 ± 0.061	1.764AsnArg: 1.764 ± 0.053	1.684AsnSer: 1.684 ± 0.068	1.761AsnThr: 1.761 ± 0.062	2.035AsnVal: 2.035 ± 0.063	0.562AsnTrp: 0.562 ± 0.033	1.008AsnTyr: 1.008 ± 0.049	0.0AsnXaa: 0.0 ± 0.0
Pro	6.443ProAla: 6.443 ± 0.139	0.274ProCys: 0.274 ± 0.022	2.82ProAsp: 2.82 ± 0.07	5.19ProGlu: 5.19 ± 0.129	1.727ProPhe: 1.727 ± 0.052	4.49ProGly: 4.49 ± 0.1	0.957ProHis: 0.957 ± 0.032	2.346ProIle: 2.346 ± 0.063	2.67ProLys: 2.67 ± 0.085	4.691ProLeu: 4.691 ± 0.098	0.962ProMet: 0.962 ± 0.043	1.785ProAsn: 1.785 ± 0.057	1.699ProPro: 1.699 ± 0.068	2.694ProGln: 2.694 ± 0.08	2.432ProArg: 2.432 ± 0.073	2.978ProSer: 2.978 ± 0.078	3.222ProThr: 3.222 ± 0.088	4.385ProVal: 4.385 ± 0.122	0.826ProTrp: 0.826 ± 0.042	1.248ProTyr: 1.248 ± 0.048	0.0ProXaa: 0.0 ± 0.0
Gln	5.391GlnAla: 5.391 ± 0.115	0.276GlnCys: 0.276 ± 0.022	1.74GlnAsp: 1.74 ± 0.056	2.382GlnGlu: 2.382 ± 0.067	1.119GlnPhe: 1.119 ± 0.047	2.91GlnGly: 2.91 ± 0.086	0.729GlnHis: 0.729 ± 0.038	2.632GlnIle: 2.632 ± 0.063	1.929GlnLys: 1.929 ± 0.065	4.422GlnLeu: 4.422 ± 0.11	0.94GlnMet: 0.94 ± 0.034	1.381GlnAsn: 1.381 ± 0.052	2.178GlnPro: 2.178 ± 0.075	2.011GlnGln: 2.011 ± 0.074	2.271GlnArg: 2.271 ± 0.079	2.144GlnSer: 2.144 ± 0.063	2.105GlnThr: 2.105 ± 0.068	4.041GlnVal: 4.041 ± 0.089	0.623GlnTrp: 0.623 ± 0.035	0.977GlnTyr: 0.977 ± 0.046	0.0GlnXaa: 0.0 ± 0.0
Arg	5.449ArgAla: 5.449 ± 0.116	0.383ArgCys: 0.383 ± 0.029	2.728ArgAsp: 2.728 ± 0.081	3.649ArgGlu: 3.649 ± 0.093	2.071ArgPhe: 2.071 ± 0.061	3.755ArgGly: 3.755 ± 0.089	1.005ArgHis: 1.005 ± 0.04	3.082ArgIle: 3.082 ± 0.073	2.433ArgLys: 2.433 ± 0.078	5.457ArgLeu: 5.457 ± 0.113	1.304ArgMet: 1.304 ± 0.048	1.722ArgAsn: 1.722 ± 0.061	2.755ArgPro: 2.755 ± 0.08	2.35ArgGln: 2.35 ± 0.075	3.744ArgArg: 3.744 ± 0.095	3.058ArgSer: 3.058 ± 0.072	3.028ArgThr: 3.028 ± 0.081	4.16ArgVal: 4.16 ± 0.1	0.843ArgTrp: 0.843 ± 0.039	1.626ArgTyr: 1.626 ± 0.061	0.0ArgXaa: 0.0 ± 0.0
Ser	6.581SerAla: 6.581 ± 0.125	0.388SerCys: 0.388 ± 0.031	3.028SerAsp: 3.028 ± 0.083	4.024SerGlu: 4.024 ± 0.089	2.236SerPhe: 2.236 ± 0.063	5.401SerGly: 5.401 ± 0.105	1.037SerHis: 1.037 ± 0.049	2.665SerIle: 2.665 ± 0.076	2.34SerLys: 2.34 ± 0.078	5.944SerLeu: 5.944 ± 0.11	1.18SerMet: 1.18 ± 0.051	1.686SerAsn: 1.686 ± 0.062	2.784SerPro: 2.784 ± 0.068	2.433SerGln: 2.433 ± 0.07	3.05SerArg: 3.05 ± 0.072	3.727SerSer: 3.727 ± 0.102	3.346SerThr: 3.346 ± 0.086	4.196SerVal: 4.196 ± 0.091	0.856SerTrp: 0.856 ± 0.045	1.444SerTyr: 1.444 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	5.679ThrAla: 5.679 ± 0.109	0.506ThrCys: 0.506 ± 0.034	2.947ThrAsp: 2.947 ± 0.074	3.581ThrGlu: 3.581 ± 0.089	2.215ThrPhe: 2.215 ± 0.069	4.759ThrGly: 4.759 ± 0.089	1.11ThrHis: 1.11 ± 0.037	3.005ThrIle: 3.005 ± 0.072	2.488ThrLys: 2.488 ± 0.077	5.849ThrLeu: 5.849 ± 0.115	1.061ThrMet: 1.061 ± 0.04	1.75ThrAsn: 1.75 ± 0.062	3.613ThrPro: 3.613 ± 0.087	2.241ThrGln: 2.241 ± 0.074	2.76ThrArg: 2.76 ± 0.079	3.457ThrSer: 3.457 ± 0.082	3.159ThrThr: 3.159 ± 0.081	4.545ThrVal: 4.545 ± 0.099	0.933ThrTrp: 0.933 ± 0.035	1.595ThrTyr: 1.595 ± 0.059	0.0ThrXaa: 0.0 ± 0.0
Val	8.132ValAla: 8.132 ± 0.14	0.628ValCys: 0.628 ± 0.037	4.308ValAsp: 4.308 ± 0.086	4.676ValGlu: 4.676 ± 0.109	2.685ValPhe: 2.685 ± 0.076	5.42ValGly: 5.42 ± 0.111	1.357ValHis: 1.357 ± 0.049	4.259ValIle: 4.259 ± 0.097	3.351ValLys: 3.351 ± 0.079	7.661ValLeu: 7.661 ± 0.126	1.643ValMet: 1.643 ± 0.069	2.401ValAsn: 2.401 ± 0.062	4.23ValPro: 4.23 ± 0.109	2.333ValGln: 2.333 ± 0.056	3.961ValArg: 3.961 ± 0.098	4.637ValSer: 4.637 ± 0.099	4.712ValThr: 4.712 ± 0.115	6.127ValVal: 6.127 ± 0.12	0.896ValTrp: 0.896 ± 0.041	1.635ValTyr: 1.635 ± 0.055	0.0ValXaa: 0.0 ± 0.0
Trp	1.449TrpAla: 1.449 ± 0.057	0.133TrpCys: 0.133 ± 0.014	0.797TrpAsp: 0.797 ± 0.039	0.892TrpGlu: 0.892 ± 0.045	0.577TrpPhe: 0.577 ± 0.031	0.962TrpGly: 0.962 ± 0.043	0.32TrpHis: 0.32 ± 0.024	0.739TrpIle: 0.739 ± 0.038	0.574TrpLys: 0.574 ± 0.034	1.498TrpLeu: 1.498 ± 0.055	0.371TrpMet: 0.371 ± 0.026	0.533TrpAsn: 0.533 ± 0.034	0.637TrpPro: 0.637 ± 0.036	0.741TrpGln: 0.741 ± 0.038	0.846TrpArg: 0.846 ± 0.038	0.792TrpSer: 0.792 ± 0.037	0.751TrpThr: 0.751 ± 0.042	1.132TrpVal: 1.132 ± 0.048	0.346TrpTrp: 0.346 ± 0.027	0.371TrpTyr: 0.371 ± 0.026	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.408TyrAla: 2.408 ± 0.065	0.257TyrCys: 0.257 ± 0.023	1.32TyrAsp: 1.32 ± 0.048	1.418TyrGlu: 1.418 ± 0.054	1.069TyrPhe: 1.069 ± 0.038	2.042TyrGly: 2.042 ± 0.065	0.504TyrHis: 0.504 ± 0.031	0.955TyrIle: 0.955 ± 0.046	0.686TyrLys: 0.686 ± 0.037	3.079TyrLeu: 3.079 ± 0.072	0.359TyrMet: 0.359 ± 0.027	0.715TyrAsn: 0.715 ± 0.039	1.471TyrPro: 1.471 ± 0.053	1.464TyrGln: 1.464 ± 0.06	1.793TyrArg: 1.793 ± 0.06	1.432TyrSer: 1.432 ± 0.051	1.367TyrThr: 1.367 ± 0.051	1.74TyrVal: 1.74 ± 0.058	0.393TyrTrp: 0.393 ± 0.026	0.717TyrTyr: 0.717 ± 0.037	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 1617 proteins (587279 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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