Amino acid dipepetide frequency for Fringilla coelebs papillomavirus (isolate Chaffinch/Netherlands/Dutch) (FcPV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.665AlaAla: 8.665 ± 1.133
0.394AlaCys: 0.394 ± 0.342
3.939AlaAsp: 3.939 ± 1.031
4.726AlaGlu: 4.726 ± 1.547
2.363AlaPhe: 2.363 ± 0.817
4.726AlaGly: 4.726 ± 0.708
0.788AlaHis: 0.788 ± 0.381
2.757AlaIle: 2.757 ± 0.808
3.151AlaLys: 3.151 ± 1.26
5.514AlaLeu: 5.514 ± 2.459
1.182AlaMet: 1.182 ± 0.415
3.151AlaAsn: 3.151 ± 0.73
4.332AlaPro: 4.332 ± 1.623
1.969AlaGln: 1.969 ± 0.622
2.363AlaArg: 2.363 ± 0.528
5.12AlaSer: 5.12 ± 0.721
3.939AlaThr: 3.939 ± 1.106
4.332AlaVal: 4.332 ± 0.782
0.394AlaTrp: 0.394 ± 0.342
1.575AlaTyr: 1.575 ± 0.599
0.0AlaXaa: 0.0 ± 0.0
Cys
1.182CysAla: 1.182 ± 0.727
0.394CysCys: 0.394 ± 0.455
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.182CysPhe: 1.182 ± 0.741
1.182CysGly: 1.182 ± 0.632
0.788CysHis: 0.788 ± 0.835
1.575CysIle: 1.575 ± 0.978
1.182CysLys: 1.182 ± 0.71
1.969CysLeu: 1.969 ± 0.923
0.394CysMet: 0.394 ± 0.341
0.788CysAsn: 0.788 ± 0.681
1.969CysPro: 1.969 ± 0.941
1.182CysGln: 1.182 ± 0.893
1.575CysArg: 1.575 ± 0.621
2.757CysSer: 2.757 ± 1.05
1.182CysThr: 1.182 ± 0.632
0.788CysVal: 0.788 ± 0.501
0.394CysTrp: 0.394 ± 0.341
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.151AspAla: 3.151 ± 0.957
1.575AspCys: 1.575 ± 0.599
3.151AspAsp: 3.151 ± 1.101
3.939AspGlu: 3.939 ± 1.508
2.363AspPhe: 2.363 ± 0.722
3.151AspGly: 3.151 ± 0.905
0.788AspHis: 0.788 ± 0.501
3.939AspIle: 3.939 ± 1.438
1.969AspLys: 1.969 ± 0.758
4.726AspLeu: 4.726 ± 1.111
0.394AspMet: 0.394 ± 0.342
2.363AspAsn: 2.363 ± 0.509
5.908AspPro: 5.908 ± 1.161
1.182AspGln: 1.182 ± 0.592
2.363AspArg: 2.363 ± 0.834
4.726AspSer: 4.726 ± 1.706
5.12AspThr: 5.12 ± 1.026
4.726AspVal: 4.726 ± 1.543
2.363AspTrp: 2.363 ± 0.859
1.182AspTyr: 1.182 ± 0.637
0.0AspXaa: 0.0 ± 0.0
Glu
3.939GluAla: 3.939 ± 1.074
2.363GluCys: 2.363 ± 0.701
5.12GluAsp: 5.12 ± 0.883
5.12GluGlu: 5.12 ± 2.167
2.363GluPhe: 2.363 ± 1.08
7.877GluGly: 7.877 ± 1.04
1.575GluHis: 1.575 ± 0.481
2.363GluIle: 2.363 ± 1.342
1.182GluLys: 1.182 ± 0.639
5.514GluLeu: 5.514 ± 1.212
1.182GluMet: 1.182 ± 0.669
2.757GluAsn: 2.757 ± 1.151
3.151GluPro: 3.151 ± 1.284
1.969GluGln: 1.969 ± 0.633
2.757GluArg: 2.757 ± 0.772
3.939GluSer: 3.939 ± 1.672
4.726GluThr: 4.726 ± 1.065
1.575GluVal: 1.575 ± 0.63
1.182GluTrp: 1.182 ± 0.452
2.757GluTyr: 2.757 ± 0.618
0.0GluXaa: 0.0 ± 0.0
Phe
1.575PheAla: 1.575 ± 0.897
0.788PheCys: 0.788 ± 0.65
0.788PheAsp: 0.788 ± 0.621
3.939PheGlu: 3.939 ± 1.252
1.182PhePhe: 1.182 ± 0.726
1.575PheGly: 1.575 ± 0.686
0.394PheHis: 0.394 ± 0.386
1.575PheIle: 1.575 ± 1.0
1.182PheLys: 1.182 ± 0.726
2.363PheLeu: 2.363 ± 1.192
0.788PheMet: 0.788 ± 0.368
3.151PheAsn: 3.151 ± 0.75
3.545PhePro: 3.545 ± 1.128
1.575PheGln: 1.575 ± 0.599
1.182PheArg: 1.182 ± 0.723
1.575PheSer: 1.575 ± 0.494
1.182PheThr: 1.182 ± 0.48
2.363PheVal: 2.363 ± 0.802
0.394PheTrp: 0.394 ± 0.341
2.757PheTyr: 2.757 ± 0.979
0.0PheXaa: 0.0 ± 0.0
Gly
5.514GlyAla: 5.514 ± 1.55
1.182GlyCys: 1.182 ± 0.637
4.726GlyAsp: 4.726 ± 0.715
3.545GlyGlu: 3.545 ± 0.759
1.575GlyPhe: 1.575 ± 0.365
4.332GlyGly: 4.332 ± 1.043
1.969GlyHis: 1.969 ± 0.628
2.757GlyIle: 2.757 ± 1.213
1.182GlyLys: 1.182 ± 0.595
7.483GlyLeu: 7.483 ± 2.024
1.182GlyMet: 1.182 ± 0.759
3.939GlyAsn: 3.939 ± 0.632
2.363GlyPro: 2.363 ± 0.485
1.182GlyGln: 1.182 ± 0.696
5.12GlyArg: 5.12 ± 1.262
9.846GlySer: 9.846 ± 2.62
4.332GlyThr: 4.332 ± 1.784
7.877GlyVal: 7.877 ± 1.302
0.788GlyTrp: 0.788 ± 0.489
1.182GlyTyr: 1.182 ± 0.323
0.0GlyXaa: 0.0 ± 0.0
His
0.394HisAla: 0.394 ± 0.341
0.788HisCys: 0.788 ± 0.909
0.788HisAsp: 0.788 ± 0.368
0.788HisGlu: 0.788 ± 0.621
1.182HisPhe: 1.182 ± 0.726
1.969HisGly: 1.969 ± 0.789
1.182HisHis: 1.182 ± 0.323
1.182HisIle: 1.182 ± 0.662
0.394HisLys: 0.394 ± 0.341
1.969HisLeu: 1.969 ± 1.05
0.788HisMet: 0.788 ± 0.368
0.788HisAsn: 0.788 ± 0.456
1.182HisPro: 1.182 ± 0.624
0.788HisGln: 0.788 ± 0.642
1.969HisArg: 1.969 ± 0.867
2.363HisSer: 2.363 ± 1.55
1.575HisThr: 1.575 ± 0.767
1.182HisVal: 1.182 ± 0.499
0.788HisTrp: 0.788 ± 0.481
0.788HisTyr: 0.788 ± 0.489
0.0HisXaa: 0.0 ± 0.0
Ile
3.151IleAla: 3.151 ± 1.102
1.575IleCys: 1.575 ± 0.988
3.151IleAsp: 3.151 ± 0.85
2.757IleGlu: 2.757 ± 1.324
0.788IlePhe: 0.788 ± 0.529
3.545IleGly: 3.545 ± 1.296
0.788IleHis: 0.788 ± 0.489
0.788IleIle: 0.788 ± 0.772
1.182IleLys: 1.182 ± 0.409
5.514IleLeu: 5.514 ± 0.612
0.394IleMet: 0.394 ± 0.342
0.788IleAsn: 0.788 ± 0.398
2.757IlePro: 2.757 ± 0.886
2.363IleGln: 2.363 ± 0.587
1.575IleArg: 1.575 ± 0.494
3.545IleSer: 3.545 ± 1.019
3.545IleThr: 3.545 ± 0.7
2.363IleVal: 2.363 ± 0.819
0.394IleTrp: 0.394 ± 0.334
1.969IleTyr: 1.969 ± 0.535
0.0IleXaa: 0.0 ± 0.0
Lys
1.182LysAla: 1.182 ± 1.022
1.575LysCys: 1.575 ± 0.607
1.969LysAsp: 1.969 ± 0.738
1.969LysGlu: 1.969 ± 0.928
0.788LysPhe: 0.788 ± 0.381
1.969LysGly: 1.969 ± 0.928
3.151LysHis: 3.151 ± 0.971
1.182LysIle: 1.182 ± 0.36
2.363LysLys: 2.363 ± 0.804
3.545LysLeu: 3.545 ± 1.467
0.788LysMet: 0.788 ± 0.381
2.757LysAsn: 2.757 ± 0.815
0.788LysPro: 0.788 ± 0.484
1.182LysGln: 1.182 ± 0.641
3.939LysArg: 3.939 ± 1.045
2.757LysSer: 2.757 ± 1.054
1.575LysThr: 1.575 ± 0.643
1.575LysVal: 1.575 ± 1.012
0.394LysTrp: 0.394 ± 0.342
3.151LysTyr: 3.151 ± 0.691
0.0LysXaa: 0.0 ± 0.0
Leu
3.151LeuAla: 3.151 ± 0.95
2.363LeuCys: 2.363 ± 0.608
3.151LeuAsp: 3.151 ± 0.624
2.757LeuGlu: 2.757 ± 0.525
4.332LeuPhe: 4.332 ± 1.142
5.908LeuGly: 5.908 ± 1.482
1.575LeuHis: 1.575 ± 0.897
3.939LeuIle: 3.939 ± 0.831
4.332LeuLys: 4.332 ± 1.38
7.877LeuLeu: 7.877 ± 2.506
0.394LeuMet: 0.394 ± 0.386
2.757LeuAsn: 2.757 ± 1.112
7.877LeuPro: 7.877 ± 1.429
6.696LeuGln: 6.696 ± 0.635
5.514LeuArg: 5.514 ± 1.534
6.302LeuSer: 6.302 ± 1.743
5.908LeuThr: 5.908 ± 1.902
5.514LeuVal: 5.514 ± 0.914
1.575LeuTrp: 1.575 ± 0.642
3.939LeuTyr: 3.939 ± 0.663
0.0LeuXaa: 0.0 ± 0.0
Met
1.575MetAla: 1.575 ± 0.93
0.0MetCys: 0.0 ± 0.0
0.788MetAsp: 0.788 ± 0.381
1.575MetGlu: 1.575 ± 0.633
1.575MetPhe: 1.575 ± 0.686
0.394MetGly: 0.394 ± 0.418
0.788MetHis: 0.788 ± 0.501
0.394MetIle: 0.394 ± 0.341
0.394MetLys: 0.394 ± 0.342
1.182MetLeu: 1.182 ± 0.36
0.0MetMet: 0.0 ± 0.0
0.788MetAsn: 0.788 ± 0.684
0.788MetPro: 0.788 ± 0.642
1.575MetGln: 1.575 ± 0.917
1.182MetArg: 1.182 ± 0.632
1.182MetSer: 1.182 ± 0.637
1.182MetThr: 1.182 ± 0.759
0.788MetVal: 0.788 ± 0.398
0.394MetTrp: 0.394 ± 0.341
0.394MetTyr: 0.394 ± 0.341
0.0MetXaa: 0.0 ± 0.0
Asn
4.726AsnAla: 4.726 ± 1.032
0.394AsnCys: 0.394 ± 0.334
0.788AsnAsp: 0.788 ± 0.484
2.757AsnGlu: 2.757 ± 0.724
1.969AsnPhe: 1.969 ± 0.853
2.363AsnGly: 2.363 ± 0.731
0.0AsnHis: 0.0 ± 0.0
1.182AsnIle: 1.182 ± 0.409
1.182AsnLys: 1.182 ± 0.662
2.757AsnLeu: 2.757 ± 1.303
0.0AsnMet: 0.0 ± 0.0
3.939AsnAsn: 3.939 ± 1.893
5.12AsnPro: 5.12 ± 0.973
2.363AsnGln: 2.363 ± 0.867
5.514AsnArg: 5.514 ± 1.384
3.151AsnSer: 3.151 ± 1.081
1.575AsnThr: 1.575 ± 0.686
2.363AsnVal: 2.363 ± 1.044
0.0AsnTrp: 0.0 ± 0.0
1.969AsnTyr: 1.969 ± 0.689
0.0AsnXaa: 0.0 ± 0.0
Pro
5.12ProAla: 5.12 ± 1.082
0.788ProCys: 0.788 ± 0.681
4.332ProAsp: 4.332 ± 1.519
5.12ProGlu: 5.12 ± 0.73
2.363ProPhe: 2.363 ± 1.274
3.545ProGly: 3.545 ± 1.199
0.0ProHis: 0.0 ± 0.0
3.939ProIle: 3.939 ± 1.629
3.545ProLys: 3.545 ± 0.829
5.514ProLeu: 5.514 ± 1.332
1.182ProMet: 1.182 ± 0.608
1.969ProAsn: 1.969 ± 0.887
7.877ProPro: 7.877 ± 1.837
3.545ProGln: 3.545 ± 1.035
3.545ProArg: 3.545 ± 1.475
6.696ProSer: 6.696 ± 2.41
2.363ProThr: 2.363 ± 0.335
5.12ProVal: 5.12 ± 1.867
0.394ProTrp: 0.394 ± 0.334
3.545ProTyr: 3.545 ± 1.489
0.0ProXaa: 0.0 ± 0.0
Gln
1.969GlnAla: 1.969 ± 0.63
0.788GlnCys: 0.788 ± 0.909
1.969GlnAsp: 1.969 ± 0.67
2.363GlnGlu: 2.363 ± 0.958
1.182GlnPhe: 1.182 ± 0.452
5.12GlnGly: 5.12 ± 1.389
1.182GlnHis: 1.182 ± 0.409
2.363GlnIle: 2.363 ± 0.881
1.182GlnLys: 1.182 ± 0.595
5.908GlnLeu: 5.908 ± 1.695
1.969GlnMet: 1.969 ± 0.382
1.182GlnAsn: 1.182 ± 0.551
2.757GlnPro: 2.757 ± 0.376
3.151GlnGln: 3.151 ± 1.762
1.969GlnArg: 1.969 ± 0.557
1.575GlnSer: 1.575 ± 0.762
2.363GlnThr: 2.363 ± 0.749
1.969GlnVal: 1.969 ± 1.28
0.394GlnTrp: 0.394 ± 0.341
0.394GlnTyr: 0.394 ± 0.342
0.0GlnXaa: 0.0 ± 0.0
Arg
3.939ArgAla: 3.939 ± 1.061
1.182ArgCys: 1.182 ± 0.442
4.332ArgAsp: 4.332 ± 0.989
5.514ArgGlu: 5.514 ± 1.013
1.182ArgPhe: 1.182 ± 0.36
2.757ArgGly: 2.757 ± 1.1
1.575ArgHis: 1.575 ± 0.486
3.151ArgIle: 3.151 ± 1.019
3.545ArgLys: 3.545 ± 1.067
6.302ArgLeu: 6.302 ± 1.243
1.182ArgMet: 1.182 ± 0.56
2.363ArgAsn: 2.363 ± 0.527
2.757ArgPro: 2.757 ± 1.123
1.182ArgGln: 1.182 ± 0.662
8.665ArgArg: 8.665 ± 3.736
3.545ArgSer: 3.545 ± 0.818
2.757ArgThr: 2.757 ± 0.686
4.726ArgVal: 4.726 ± 1.132
0.788ArgTrp: 0.788 ± 0.433
2.363ArgTyr: 2.363 ± 0.679
0.0ArgXaa: 0.0 ± 0.0
Ser
6.696SerAla: 6.696 ± 1.309
1.575SerCys: 1.575 ± 0.621
4.726SerAsp: 4.726 ± 0.802
5.12SerGlu: 5.12 ± 2.494
1.182SerPhe: 1.182 ± 0.726
9.453SerGly: 9.453 ± 1.912
1.182SerHis: 1.182 ± 0.71
3.939SerIle: 3.939 ± 1.159
3.939SerLys: 3.939 ± 1.849
5.12SerLeu: 5.12 ± 1.545
1.575SerMet: 1.575 ± 0.919
5.514SerAsn: 5.514 ± 1.644
3.939SerPro: 3.939 ± 1.168
4.726SerGln: 4.726 ± 0.576
3.939SerArg: 3.939 ± 1.303
10.634SerSer: 10.634 ± 2.435
5.908SerThr: 5.908 ± 0.583
3.939SerVal: 3.939 ± 0.644
0.788SerTrp: 0.788 ± 0.642
1.575SerTyr: 1.575 ± 0.692
0.0SerXaa: 0.0 ± 0.0
Thr
2.757ThrAla: 2.757 ± 1.467
0.788ThrCys: 0.788 ± 0.381
5.908ThrAsp: 5.908 ± 0.487
4.726ThrGlu: 4.726 ± 1.125
1.575ThrPhe: 1.575 ± 0.654
3.939ThrGly: 3.939 ± 1.347
1.575ThrHis: 1.575 ± 0.59
1.969ThrIle: 1.969 ± 0.628
2.757ThrLys: 2.757 ± 0.808
3.545ThrLeu: 3.545 ± 1.034
1.575ThrMet: 1.575 ± 0.965
1.575ThrAsn: 1.575 ± 0.963
4.726ThrPro: 4.726 ± 1.115
1.969ThrGln: 1.969 ± 0.772
3.151ThrArg: 3.151 ± 0.962
6.302ThrSer: 6.302 ± 0.862
0.394ThrThr: 0.394 ± 0.342
7.483ThrVal: 7.483 ± 1.133
0.394ThrTrp: 0.394 ± 0.386
1.182ThrTyr: 1.182 ± 0.673
0.0ThrXaa: 0.0 ± 0.0
Val
4.332ValAla: 4.332 ± 0.901
0.788ValCys: 0.788 ± 0.65
5.514ValAsp: 5.514 ± 1.393
3.151ValGlu: 3.151 ± 0.585
3.151ValPhe: 3.151 ± 1.443
4.726ValGly: 4.726 ± 2.06
1.969ValHis: 1.969 ± 0.797
2.757ValIle: 2.757 ± 1.232
1.969ValLys: 1.969 ± 1.172
3.939ValLeu: 3.939 ± 1.159
1.182ValMet: 1.182 ± 0.583
1.969ValAsn: 1.969 ± 0.976
7.089ValPro: 7.089 ± 2.28
1.575ValGln: 1.575 ± 0.654
5.12ValArg: 5.12 ± 0.604
5.12ValSer: 5.12 ± 1.444
5.514ValThr: 5.514 ± 1.675
3.151ValVal: 3.151 ± 1.428
0.788ValTrp: 0.788 ± 0.481
1.575ValTyr: 1.575 ± 0.577
0.0ValXaa: 0.0 ± 0.0
Trp
0.788TrpAla: 0.788 ± 0.381
0.788TrpCys: 0.788 ± 0.489
1.182TrpAsp: 1.182 ± 0.452
1.182TrpGlu: 1.182 ± 0.946
0.394TrpPhe: 0.394 ± 0.386
1.575TrpGly: 1.575 ± 0.792
0.394TrpHis: 0.394 ± 0.386
0.394TrpIle: 0.394 ± 0.342
0.788TrpLys: 0.788 ± 0.381
2.757TrpLeu: 2.757 ± 0.833
0.0TrpMet: 0.0 ± 0.0
0.394TrpAsn: 0.394 ± 0.342
0.0TrpPro: 0.0 ± 0.0
0.788TrpGln: 0.788 ± 0.684
0.788TrpArg: 0.788 ± 0.398
0.394TrpSer: 0.394 ± 0.386
0.788TrpThr: 0.788 ± 0.456
1.575TrpVal: 1.575 ± 0.544
0.394TrpTrp: 0.394 ± 0.334
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.575TyrAla: 1.575 ± 0.643
0.394TyrCys: 0.394 ± 0.341
2.757TyrAsp: 2.757 ± 1.578
2.363TyrGlu: 2.363 ± 0.351
1.182TyrPhe: 1.182 ± 0.551
1.969TyrGly: 1.969 ± 0.499
1.182TyrHis: 1.182 ± 0.637
0.788TyrIle: 0.788 ± 0.381
1.182TyrLys: 1.182 ± 0.637
2.363TyrLeu: 2.363 ± 0.628
0.394TyrMet: 0.394 ± 0.342
1.182TyrAsn: 1.182 ± 0.662
1.969TyrPro: 1.969 ± 0.739
0.788TyrGln: 0.788 ± 0.368
1.575TyrArg: 1.575 ± 1.05
3.939TyrSer: 3.939 ± 1.138
2.363TyrThr: 2.363 ± 1.069
1.969TyrVal: 1.969 ± 0.633
2.363TyrTrp: 2.363 ± 1.16
1.575TyrTyr: 1.575 ± 0.599
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2540 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski