Amino acid dipepetide frequency for Gulosibacter molinativorax

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.139AlaAla: 16.139 ± 0.218	0.583AlaCys: 0.583 ± 0.026	7.152AlaAsp: 7.152 ± 0.102	8.514AlaGlu: 8.514 ± 0.129	3.649AlaPhe: 3.649 ± 0.063	10.344AlaGly: 10.344 ± 0.118	2.291AlaHis: 2.291 ± 0.054	6.324AlaIle: 6.324 ± 0.092	3.492AlaLys: 3.492 ± 0.074	12.1AlaLeu: 12.1 ± 0.144	2.731AlaMet: 2.731 ± 0.05	3.013AlaAsn: 3.013 ± 0.056	5.279AlaPro: 5.279 ± 0.086	4.045AlaGln: 4.045 ± 0.071	7.794AlaArg: 7.794 ± 0.12	7.388AlaSer: 7.388 ± 0.104	7.266AlaThr: 7.266 ± 0.096	9.307AlaVal: 9.307 ± 0.105	1.578AlaTrp: 1.578 ± 0.038	2.199AlaTyr: 2.199 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.617CysAla: 0.617 ± 0.027	0.053CysCys: 0.053 ± 0.008	0.293CysAsp: 0.293 ± 0.015	0.282CysGlu: 0.282 ± 0.018	0.163CysPhe: 0.163 ± 0.012	0.528CysGly: 0.528 ± 0.027	0.12CysHis: 0.12 ± 0.011	0.221CysIle: 0.221 ± 0.013	0.097CysLys: 0.097 ± 0.011	0.379CysLeu: 0.379 ± 0.021	0.086CysMet: 0.086 ± 0.009	0.115CysAsn: 0.115 ± 0.012	0.275CysPro: 0.275 ± 0.018	0.148CysGln: 0.148 ± 0.012	0.319CysArg: 0.319 ± 0.019	0.303CysSer: 0.303 ± 0.02	0.29CysThr: 0.29 ± 0.016	0.397CysVal: 0.397 ± 0.02	0.071CysTrp: 0.071 ± 0.008	0.114CysTyr: 0.114 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	8.633AspAla: 8.633 ± 0.117	0.219AspCys: 0.219 ± 0.016	3.536AspAsp: 3.536 ± 0.079	4.672AspGlu: 4.672 ± 0.077	1.851AspPhe: 1.851 ± 0.046	5.329AspGly: 5.329 ± 0.103	1.21AspHis: 1.21 ± 0.039	2.602AspIle: 2.602 ± 0.055	1.24AspLys: 1.24 ± 0.037	5.898AspLeu: 5.898 ± 0.082	0.959AspMet: 0.959 ± 0.034	1.236AspAsn: 1.236 ± 0.039	3.483AspPro: 3.483 ± 0.055	1.834AspGln: 1.834 ± 0.049	4.211AspArg: 4.211 ± 0.075	3.136AspSer: 3.136 ± 0.06	3.041AspThr: 3.041 ± 0.067	4.822AspVal: 4.822 ± 0.072	0.928AspTrp: 0.928 ± 0.037	1.394AspTyr: 1.394 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	7.644GluAla: 7.644 ± 0.117	0.258GluCys: 0.258 ± 0.019	3.65GluAsp: 3.65 ± 0.071	3.949GluGlu: 3.949 ± 0.073	2.356GluPhe: 2.356 ± 0.052	4.538GluGly: 4.538 ± 0.068	1.735GluHis: 1.735 ± 0.039	3.678GluIle: 3.678 ± 0.068	1.652GluLys: 1.652 ± 0.047	7.364GluLeu: 7.364 ± 0.104	1.25GluMet: 1.25 ± 0.036	1.687GluAsn: 1.687 ± 0.048	3.32GluPro: 3.32 ± 0.065	2.907GluGln: 2.907 ± 0.056	5.622GluArg: 5.622 ± 0.099	3.909GluSer: 3.909 ± 0.062	3.67GluThr: 3.67 ± 0.077	5.093GluVal: 5.093 ± 0.074	0.97GluTrp: 0.97 ± 0.03	1.506GluTyr: 1.506 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	4.246PheAla: 4.246 ± 0.067	0.165PheCys: 0.165 ± 0.012	2.412PheAsp: 2.412 ± 0.053	2.17PheGlu: 2.17 ± 0.046	1.093PhePhe: 1.093 ± 0.035	3.578PheGly: 3.578 ± 0.061	0.564PheHis: 0.564 ± 0.024	1.536PheIle: 1.536 ± 0.044	0.685PheLys: 0.685 ± 0.029	2.844PheLeu: 2.844 ± 0.053	0.595PheMet: 0.595 ± 0.027	0.875PheAsn: 0.875 ± 0.03	1.444PhePro: 1.444 ± 0.034	0.835PheGln: 0.835 ± 0.033	1.803PheArg: 1.803 ± 0.044	1.924PheSer: 1.924 ± 0.042	2.075PheThr: 2.075 ± 0.047	2.824PheVal: 2.824 ± 0.061	0.443PheTrp: 0.443 ± 0.021	0.671PheTyr: 0.671 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	9.522GlyAla: 9.522 ± 0.109	0.52GlyCys: 0.52 ± 0.024	4.765GlyAsp: 4.765 ± 0.081	5.507GlyGlu: 5.507 ± 0.078	3.179GlyPhe: 3.179 ± 0.07	6.901GlyGly: 6.901 ± 0.112	1.835GlyHis: 1.835 ± 0.043	5.024GlyIle: 5.024 ± 0.074	2.748GlyLys: 2.748 ± 0.061	8.121GlyLeu: 8.121 ± 0.098	2.05GlyMet: 2.05 ± 0.047	2.13GlyAsn: 2.13 ± 0.053	3.295GlyPro: 3.295 ± 0.067	2.927GlyGln: 2.927 ± 0.082	5.518GlyArg: 5.518 ± 0.083	5.212GlySer: 5.212 ± 0.081	5.232GlyThr: 5.232 ± 0.07	6.998GlyVal: 6.998 ± 0.09	1.458GlyTrp: 1.458 ± 0.038	2.294GlyTyr: 2.294 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	2.221HisAla: 2.221 ± 0.052	0.126HisCys: 0.126 ± 0.011	1.374HisAsp: 1.374 ± 0.041	1.409HisGlu: 1.409 ± 0.039	0.639HisPhe: 0.639 ± 0.021	1.879HisGly: 1.879 ± 0.045	0.539HisHis: 0.539 ± 0.026	0.846HisIle: 0.846 ± 0.029	0.378HisLys: 0.378 ± 0.02	1.872HisLeu: 1.872 ± 0.039	0.373HisMet: 0.373 ± 0.019	0.449HisAsn: 0.449 ± 0.024	1.497HisPro: 1.497 ± 0.046	0.578HisGln: 0.578 ± 0.026	1.493HisArg: 1.493 ± 0.036	1.103HisSer: 1.103 ± 0.032	1.133HisThr: 1.133 ± 0.029	1.601HisVal: 1.601 ± 0.044	0.327HisTrp: 0.327 ± 0.017	0.479HisTyr: 0.479 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	7.147IleAla: 7.147 ± 0.09	0.264IleCys: 0.264 ± 0.015	3.804IleAsp: 3.804 ± 0.064	3.594IleGlu: 3.594 ± 0.058	1.382IlePhe: 1.382 ± 0.032	5.025IleGly: 5.025 ± 0.081	0.923IleHis: 0.923 ± 0.028	2.402IleIle: 2.402 ± 0.061	0.98IleLys: 0.98 ± 0.033	4.305IleLeu: 4.305 ± 0.065	0.765IleMet: 0.765 ± 0.031	1.23IleAsn: 1.23 ± 0.036	2.654IlePro: 2.654 ± 0.057	1.262IleGln: 1.262 ± 0.04	3.244IleArg: 3.244 ± 0.058	2.85IleSer: 2.85 ± 0.05	3.254IleThr: 3.254 ± 0.058	4.78IleVal: 4.78 ± 0.074	0.595IleTrp: 0.595 ± 0.03	0.889IleTyr: 0.889 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	2.716LysAla: 2.716 ± 0.064	0.091LysCys: 0.091 ± 0.01	1.309LysAsp: 1.309 ± 0.039	1.328LysGlu: 1.328 ± 0.044	0.874LysPhe: 0.874 ± 0.032	1.736LysGly: 1.736 ± 0.047	0.627LysHis: 0.627 ± 0.029	1.307LysIle: 1.307 ± 0.039	0.986LysLys: 0.986 ± 0.039	2.653LysLeu: 2.653 ± 0.055	0.563LysMet: 0.563 ± 0.024	0.736LysAsn: 0.736 ± 0.031	1.499LysPro: 1.499 ± 0.049	1.069LysGln: 1.069 ± 0.034	2.172LysArg: 2.172 ± 0.047	1.621LysSer: 1.621 ± 0.044	1.535LysThr: 1.535 ± 0.044	1.971LysVal: 1.971 ± 0.046	0.36LysTrp: 0.36 ± 0.019	0.622LysTyr: 0.622 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	12.81LeuAla: 12.81 ± 0.154	0.472LeuCys: 0.472 ± 0.021	6.307LeuAsp: 6.307 ± 0.092	6.394LeuGlu: 6.394 ± 0.078	2.961LeuPhe: 2.961 ± 0.056	8.8LeuGly: 8.8 ± 0.091	1.806LeuHis: 1.806 ± 0.052	4.891LeuIle: 4.891 ± 0.091	2.199LeuLys: 2.199 ± 0.053	9.374LeuLeu: 9.374 ± 0.144	1.823LeuMet: 1.823 ± 0.048	2.27LeuAsn: 2.27 ± 0.049	5.062LeuPro: 5.062 ± 0.073	2.801LeuGln: 2.801 ± 0.058	6.936LeuArg: 6.936 ± 0.1	5.611LeuSer: 5.611 ± 0.08	6.034LeuThr: 6.034 ± 0.095	8.454LeuVal: 8.454 ± 0.126	1.129LeuTrp: 1.129 ± 0.036	1.657LeuTyr: 1.657 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	2.17MetAla: 2.17 ± 0.051	0.104MetCys: 0.104 ± 0.011	0.867MetAsp: 0.867 ± 0.029	0.729MetGlu: 0.729 ± 0.027	0.672MetPhe: 0.672 ± 0.029	1.431MetGly: 1.431 ± 0.036	0.429MetHis: 0.429 ± 0.019	1.029MetIle: 1.029 ± 0.034	0.564MetLys: 0.564 ± 0.022	2.12MetLeu: 2.12 ± 0.042	0.358MetMet: 0.358 ± 0.02	0.673MetAsn: 0.673 ± 0.022	1.191MetPro: 1.191 ± 0.038	0.665MetGln: 0.665 ± 0.027	1.614MetArg: 1.614 ± 0.041	1.591MetSer: 1.591 ± 0.04	1.704MetThr: 1.704 ± 0.041	1.432MetVal: 1.432 ± 0.038	0.27MetTrp: 0.27 ± 0.018	0.33MetTyr: 0.33 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	2.905AsnAla: 2.905 ± 0.06	0.123AsnCys: 0.123 ± 0.012	1.443AsnAsp: 1.443 ± 0.039	1.659AsnGlu: 1.659 ± 0.041	0.794AsnPhe: 0.794 ± 0.03	2.248AsnGly: 2.248 ± 0.054	0.528AsnHis: 0.528 ± 0.024	1.167AsnIle: 1.167 ± 0.033	0.601AsnLys: 0.601 ± 0.024	2.323AsnLeu: 2.323 ± 0.047	0.519AsnMet: 0.519 ± 0.023	0.684AsnAsn: 0.684 ± 0.03	1.742AsnPro: 1.742 ± 0.041	0.801AsnGln: 0.801 ± 0.032	1.743AsnArg: 1.743 ± 0.039	1.416AsnSer: 1.416 ± 0.041	1.45AsnThr: 1.45 ± 0.039	2.032AsnVal: 2.032 ± 0.048	0.453AsnTrp: 0.453 ± 0.02	0.61AsnTyr: 0.61 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	5.8ProAla: 5.8 ± 0.086	0.177ProCys: 0.177 ± 0.015	3.438ProAsp: 3.438 ± 0.053	4.417ProGlu: 4.417 ± 0.071	1.698ProPhe: 1.698 ± 0.046	4.527ProGly: 4.527 ± 0.079	0.958ProHis: 0.958 ± 0.031	2.366ProIle: 2.366 ± 0.043	1.555ProLys: 1.555 ± 0.037	4.361ProLeu: 4.361 ± 0.073	0.989ProMet: 0.989 ± 0.033	1.43ProAsn: 1.43 ± 0.038	1.807ProPro: 1.807 ± 0.056	1.584ProGln: 1.584 ± 0.039	2.917ProArg: 2.917 ± 0.056	2.895ProSer: 2.895 ± 0.06	3.166ProThr: 3.166 ± 0.073	4.216ProVal: 4.216 ± 0.077	0.755ProTrp: 0.755 ± 0.03	1.002ProTyr: 1.002 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.777GlnAla: 3.777 ± 0.062	0.139GlnCys: 0.139 ± 0.012	1.695GlnAsp: 1.695 ± 0.042	1.738GlnGlu: 1.738 ± 0.045	1.064GlnPhe: 1.064 ± 0.037	2.251GlnGly: 2.251 ± 0.054	0.808GlnHis: 0.808 ± 0.029	1.667GlnIle: 1.667 ± 0.04	0.784GlnLys: 0.784 ± 0.031	3.704GlnLeu: 3.704 ± 0.059	0.615GlnMet: 0.615 ± 0.024	0.836GlnAsn: 0.836 ± 0.028	1.761GlnPro: 1.761 ± 0.054	1.684GlnGln: 1.684 ± 0.065	2.587GlnArg: 2.587 ± 0.057	1.83GlnSer: 1.83 ± 0.044	1.681GlnThr: 1.681 ± 0.04	2.622GlnVal: 2.622 ± 0.051	0.485GlnTrp: 0.485 ± 0.023	0.758GlnTyr: 0.758 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	7.629ArgAla: 7.629 ± 0.124	0.291ArgCys: 0.291 ± 0.02	4.232ArgAsp: 4.232 ± 0.069	5.425ArgGlu: 5.425 ± 0.072	2.35ArgPhe: 2.35 ± 0.052	5.117ArgGly: 5.117 ± 0.085	1.452ArgHis: 1.452 ± 0.041	4.027ArgIle: 4.027 ± 0.065	2.106ArgLys: 2.106 ± 0.044	6.554ArgLeu: 6.554 ± 0.087	1.628ArgMet: 1.628 ± 0.038	1.726ArgAsn: 1.726 ± 0.046	3.224ArgPro: 3.224 ± 0.056	2.192ArgGln: 2.192 ± 0.046	5.434ArgArg: 5.434 ± 0.082	3.798ArgSer: 3.798 ± 0.072	3.782ArgThr: 3.782 ± 0.055	5.38ArgVal: 5.38 ± 0.077	1.067ArgTrp: 1.067 ± 0.034	1.521ArgTyr: 1.521 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	6.784SerAla: 6.784 ± 0.101	0.28SerCys: 0.28 ± 0.02	3.31SerAsp: 3.31 ± 0.059	3.564SerGlu: 3.564 ± 0.058	2.054SerPhe: 2.054 ± 0.045	5.932SerGly: 5.932 ± 0.094	1.099SerHis: 1.099 ± 0.036	3.067SerIle: 3.067 ± 0.051	1.569SerLys: 1.569 ± 0.036	5.696SerLeu: 5.696 ± 0.083	1.304SerMet: 1.304 ± 0.036	1.608SerAsn: 1.608 ± 0.041	2.962SerPro: 2.962 ± 0.058	1.767SerGln: 1.767 ± 0.041	3.763SerArg: 3.763 ± 0.067	3.728SerSer: 3.728 ± 0.079	3.764SerThr: 3.764 ± 0.064	4.651SerVal: 4.651 ± 0.068	0.901SerTrp: 0.901 ± 0.032	1.24SerTyr: 1.24 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	6.828ThrAla: 6.828 ± 0.101	0.295ThrCys: 0.295 ± 0.019	3.5ThrAsp: 3.5 ± 0.059	3.81ThrGlu: 3.81 ± 0.063	1.941ThrPhe: 1.941 ± 0.041	5.529ThrGly: 5.529 ± 0.078	1.228ThrHis: 1.228 ± 0.036	3.16ThrIle: 3.16 ± 0.063	1.536ThrLys: 1.536 ± 0.041	5.806ThrLeu: 5.806 ± 0.079	1.095ThrMet: 1.095 ± 0.033	1.547ThrAsn: 1.547 ± 0.042	3.637ThrPro: 3.637 ± 0.061	1.722ThrGln: 1.722 ± 0.043	3.61ThrArg: 3.61 ± 0.066	3.67ThrSer: 3.67 ± 0.067	3.854ThrThr: 3.854 ± 0.076	5.401ThrVal: 5.401 ± 0.078	0.866ThrTrp: 0.866 ± 0.033	1.375ThrTyr: 1.375 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	9.862ValAla: 9.862 ± 0.116	0.445ValCys: 0.445 ± 0.023	5.035ValAsp: 5.035 ± 0.078	5.434ValGlu: 5.434 ± 0.086	2.769ValPhe: 2.769 ± 0.057	6.487ValGly: 6.487 ± 0.086	1.496ValHis: 1.496 ± 0.038	4.558ValIle: 4.558 ± 0.075	1.851ValLys: 1.851 ± 0.052	8.248ValLeu: 8.248 ± 0.098	1.554ValMet: 1.554 ± 0.042	2.033ValAsn: 2.033 ± 0.048	4.235ValPro: 4.235 ± 0.07	2.361ValGln: 2.361 ± 0.052	5.345ValArg: 5.345 ± 0.081	4.981ValSer: 4.981 ± 0.076	5.543ValThr: 5.543 ± 0.075	7.38ValVal: 7.38 ± 0.101	1.02ValTrp: 1.02 ± 0.033	1.554ValTyr: 1.554 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.427TrpAla: 1.427 ± 0.037	0.103TrpCys: 0.103 ± 0.009	0.735TrpAsp: 0.735 ± 0.024	0.71TrpGlu: 0.71 ± 0.028	0.564TrpPhe: 0.564 ± 0.025	0.985TrpGly: 0.985 ± 0.033	0.337TrpHis: 0.337 ± 0.018	0.685TrpIle: 0.685 ± 0.03	0.334TrpLys: 0.334 ± 0.018	1.845TrpLeu: 1.845 ± 0.053	0.366TrpMet: 0.366 ± 0.019	0.446TrpAsn: 0.446 ± 0.023	0.623TrpPro: 0.623 ± 0.025	0.603TrpGln: 0.603 ± 0.025	1.137TrpArg: 1.137 ± 0.037	0.865TrpSer: 0.865 ± 0.032	0.777TrpThr: 0.777 ± 0.027	1.135TrpVal: 1.135 ± 0.037	0.372TrpTrp: 0.372 ± 0.022	0.312TrpTyr: 0.312 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.313TyrAla: 2.313 ± 0.05	0.164TyrCys: 0.164 ± 0.011	1.374TyrAsp: 1.374 ± 0.044	1.452TyrGlu: 1.452 ± 0.038	0.73TyrPhe: 0.73 ± 0.026	2.072TyrGly: 2.072 ± 0.062	0.332TyrHis: 0.332 ± 0.018	0.793TyrIle: 0.793 ± 0.03	0.42TyrLys: 0.42 ± 0.022	2.222TyrLeu: 2.222 ± 0.053	0.321TyrMet: 0.321 ± 0.018	0.518TyrAsn: 0.518 ± 0.023	1.065TyrPro: 1.065 ± 0.035	0.7TyrGln: 0.7 ± 0.03	1.673TyrArg: 1.673 ± 0.041	1.213TyrSer: 1.213 ± 0.035	1.157TyrThr: 1.157 ± 0.029	1.691TyrVal: 1.691 ± 0.048	0.316TyrTrp: 0.316 ± 0.021	0.507TyrTyr: 0.507 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3115 proteins (1006633 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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