Amino acid dipepetide frequency for Armillaria gallica (Bulbous honey fungus) (Armillaria bulbosa)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.614AlaAla: 6.614 ± 0.037	1.203AlaCys: 1.203 ± 0.012	3.747AlaAsp: 3.747 ± 0.024	4.143AlaGlu: 4.143 ± 0.027	3.213AlaPhe: 3.213 ± 0.022	4.624AlaGly: 4.624 ± 0.029	1.808AlaHis: 1.808 ± 0.013	4.188AlaIle: 4.188 ± 0.023	3.442AlaLys: 3.442 ± 0.025	7.745AlaLeu: 7.745 ± 0.033	1.879AlaMet: 1.879 ± 0.015	2.578AlaAsn: 2.578 ± 0.018	4.244AlaPro: 4.244 ± 0.032	2.761AlaGln: 2.761 ± 0.021	4.276AlaArg: 4.276 ± 0.024	6.768AlaSer: 6.768 ± 0.028	4.731AlaThr: 4.731 ± 0.027	5.125AlaVal: 5.125 ± 0.027	1.185AlaTrp: 1.185 ± 0.013	2.21AlaTyr: 2.21 ± 0.016	0.0AlaXaa: 0.0 ± 0.0
Cys	1.079CysAla: 1.079 ± 0.011	0.37CysCys: 0.37 ± 0.007	0.808CysAsp: 0.808 ± 0.01	0.664CysGlu: 0.664 ± 0.01	0.67CysPhe: 0.67 ± 0.007	1.019CysGly: 1.019 ± 0.012	0.518CysHis: 0.518 ± 0.009	0.927CysIle: 0.927 ± 0.01	0.663CysLys: 0.663 ± 0.008	1.675CysLeu: 1.675 ± 0.016	0.391CysMet: 0.391 ± 0.006	0.523CysAsn: 0.523 ± 0.008	0.963CysPro: 0.963 ± 0.013	0.579CysGln: 0.579 ± 0.008	1.009CysArg: 1.009 ± 0.011	1.347CysSer: 1.347 ± 0.015	0.981CysThr: 0.981 ± 0.01	0.952CysVal: 0.952 ± 0.011	0.306CysTrp: 0.306 ± 0.007	0.457CysTyr: 0.457 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.472AspAla: 4.472 ± 0.023	0.77AspCys: 0.77 ± 0.01	4.248AspAsp: 4.248 ± 0.031	3.986AspGlu: 3.986 ± 0.03	2.187AspPhe: 2.187 ± 0.016	3.817AspGly: 3.817 ± 0.023	1.338AspHis: 1.338 ± 0.014	3.593AspIle: 3.593 ± 0.022	2.209AspLys: 2.209 ± 0.018	5.152AspLeu: 5.152 ± 0.027	1.335AspMet: 1.335 ± 0.011	1.916AspAsn: 1.916 ± 0.015	3.196AspPro: 3.196 ± 0.02	1.569AspGln: 1.569 ± 0.013	2.774AspArg: 2.774 ± 0.02	4.258AspSer: 4.258 ± 0.024	3.144AspThr: 3.144 ± 0.018	4.067AspVal: 4.067 ± 0.027	0.92AspTrp: 0.92 ± 0.012	1.619AspTyr: 1.619 ± 0.014	0.0AspXaa: 0.0 ± 0.0
Glu	4.406GluAla: 4.406 ± 0.029	0.767GluCys: 0.767 ± 0.01	3.96GluAsp: 3.96 ± 0.027	4.86GluGlu: 4.86 ± 0.038	1.834GluPhe: 1.834 ± 0.014	3.463GluGly: 3.463 ± 0.024	1.452GluHis: 1.452 ± 0.014	2.933GluIle: 2.933 ± 0.019	2.999GluLys: 2.999 ± 0.021	5.016GluLeu: 5.016 ± 0.029	1.428GluMet: 1.428 ± 0.015	1.95GluAsn: 1.95 ± 0.017	2.469GluPro: 2.469 ± 0.023	1.997GluGln: 1.997 ± 0.018	3.495GluArg: 3.495 ± 0.022	3.978GluSer: 3.978 ± 0.024	3.05GluThr: 3.05 ± 0.02	3.435GluVal: 3.435 ± 0.021	0.966GluTrp: 0.966 ± 0.01	1.652GluTyr: 1.652 ± 0.014	0.0GluXaa: 0.0 ± 0.0
Phe	2.944PheAla: 2.944 ± 0.019	0.697PheCys: 0.697 ± 0.01	2.314PheAsp: 2.314 ± 0.017	2.01PheGlu: 2.01 ± 0.015	1.772PhePhe: 1.772 ± 0.016	2.648PheGly: 2.648 ± 0.019	1.088PheHis: 1.088 ± 0.011	2.167PheIle: 2.167 ± 0.017	1.592PheLys: 1.592 ± 0.014	3.93PheLeu: 3.93 ± 0.024	0.865PheMet: 0.865 ± 0.01	1.477PheAsn: 1.477 ± 0.011	2.276PhePro: 2.276 ± 0.017	1.37PheGln: 1.37 ± 0.014	2.085PheArg: 2.085 ± 0.015	3.469PheSer: 3.469 ± 0.022	2.344PheThr: 2.344 ± 0.015	2.638PheVal: 2.638 ± 0.018	0.659PheTrp: 0.659 ± 0.01	1.182PheTyr: 1.182 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	4.27GlyAla: 4.27 ± 0.025	1.019GlyCys: 1.019 ± 0.013	3.33GlyAsp: 3.33 ± 0.02	3.101GlyGlu: 3.101 ± 0.02	2.456GlyPhe: 2.456 ± 0.02	4.541GlyGly: 4.541 ± 0.034	1.687GlyHis: 1.687 ± 0.014	3.556GlyIle: 3.556 ± 0.021	3.066GlyLys: 3.066 ± 0.02	5.461GlyLeu: 5.461 ± 0.028	1.525GlyMet: 1.525 ± 0.016	2.244GlyAsn: 2.244 ± 0.015	3.013GlyPro: 3.013 ± 0.02	2.089GlyGln: 2.089 ± 0.017	3.725GlyArg: 3.725 ± 0.027	5.182GlySer: 5.182 ± 0.027	3.798GlyThr: 3.798 ± 0.025	4.064GlyVal: 4.064 ± 0.025	1.125GlyTrp: 1.125 ± 0.013	1.944GlyTyr: 1.944 ± 0.018	0.0GlyXaa: 0.0 ± 0.0
His	1.951HisAla: 1.951 ± 0.015	0.511HisCys: 0.511 ± 0.008	1.378HisAsp: 1.378 ± 0.012	1.259HisGlu: 1.259 ± 0.013	1.125HisPhe: 1.125 ± 0.012	1.657HisGly: 1.657 ± 0.014	0.976HisHis: 0.976 ± 0.013	1.567HisIle: 1.567 ± 0.015	0.989HisLys: 0.989 ± 0.012	2.777HisLeu: 2.777 ± 0.018	0.536HisMet: 0.536 ± 0.008	0.867HisAsn: 0.867 ± 0.011	1.907HisPro: 1.907 ± 0.015	1.004HisGln: 1.004 ± 0.01	1.741HisArg: 1.741 ± 0.016	2.247HisSer: 2.247 ± 0.02	1.52HisThr: 1.52 ± 0.013	1.694HisVal: 1.694 ± 0.015	0.409HisTrp: 0.409 ± 0.007	0.8HisTyr: 0.8 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.139IleAla: 4.139 ± 0.026	0.964IleCys: 0.964 ± 0.011	3.003IleAsp: 3.003 ± 0.02	2.812IleGlu: 2.812 ± 0.017	2.298IlePhe: 2.298 ± 0.017	3.031IleGly: 3.031 ± 0.021	1.523IleHis: 1.523 ± 0.014	3.114IleIle: 3.114 ± 0.022	2.177IleLys: 2.177 ± 0.016	5.444IleLeu: 5.444 ± 0.031	1.131IleMet: 1.131 ± 0.011	1.901IleAsn: 1.901 ± 0.015	3.552IlePro: 3.552 ± 0.023	1.995IleGln: 1.995 ± 0.014	3.021IleArg: 3.021 ± 0.018	4.579IleSer: 4.579 ± 0.025	3.22IleThr: 3.22 ± 0.021	3.583IleVal: 3.583 ± 0.023	0.854IleTrp: 0.854 ± 0.011	1.633IleTyr: 1.633 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	3.71LysAla: 3.71 ± 0.026	0.647LysCys: 0.647 ± 0.008	2.696LysAsp: 2.696 ± 0.021	3.083LysGlu: 3.083 ± 0.024	1.432LysPhe: 1.432 ± 0.013	2.809LysGly: 2.809 ± 0.019	1.178LysHis: 1.178 ± 0.012	2.191LysIle: 2.191 ± 0.017	2.901LysLys: 2.901 ± 0.031	3.872LysLeu: 3.872 ± 0.025	1.043LysMet: 1.043 ± 0.011	1.597LysAsn: 1.597 ± 0.016	2.299LysPro: 2.299 ± 0.02	1.615LysGln: 1.615 ± 0.013	3.121LysArg: 3.121 ± 0.021	3.268LysSer: 3.268 ± 0.019	2.627LysThr: 2.627 ± 0.018	2.768LysVal: 2.768 ± 0.02	0.693LysTrp: 0.693 ± 0.009	1.358LysTyr: 1.358 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	7.419LeuAla: 7.419 ± 0.031	1.692LeuCys: 1.692 ± 0.015	5.372LeuAsp: 5.372 ± 0.026	5.314LeuGlu: 5.314 ± 0.031	3.769LeuPhe: 3.769 ± 0.024	5.495LeuGly: 5.495 ± 0.031	2.816LeuHis: 2.816 ± 0.019	4.447LeuIle: 4.447 ± 0.029	4.254LeuLys: 4.254 ± 0.025	9.262LeuLeu: 9.262 ± 0.04	1.947LeuMet: 1.947 ± 0.016	3.286LeuAsn: 3.286 ± 0.019	6.266LeuPro: 6.266 ± 0.029	3.86LeuGln: 3.86 ± 0.022	5.962LeuArg: 5.962 ± 0.03	8.576LeuSer: 8.576 ± 0.036	5.465LeuThr: 5.465 ± 0.026	6.076LeuVal: 6.076 ± 0.027	1.459LeuTrp: 1.459 ± 0.014	2.716LeuTyr: 2.716 ± 0.019	0.0LeuXaa: 0.0 ± 0.0
Met	1.896MetAla: 1.896 ± 0.014	0.321MetCys: 0.321 ± 0.007	1.348MetAsp: 1.348 ± 0.014	1.285MetGlu: 1.285 ± 0.014	0.88MetPhe: 0.88 ± 0.01	1.285MetGly: 1.285 ± 0.013	0.615MetHis: 0.615 ± 0.008	1.123MetIle: 1.123 ± 0.012	1.098MetLys: 1.098 ± 0.012	2.069MetLeu: 2.069 ± 0.017	0.578MetMet: 0.578 ± 0.008	0.873MetAsn: 0.873 ± 0.009	1.304MetPro: 1.304 ± 0.012	0.872MetGln: 0.872 ± 0.009	1.253MetArg: 1.253 ± 0.012	2.192MetSer: 2.192 ± 0.015	1.461MetThr: 1.461 ± 0.013	1.402MetVal: 1.402 ± 0.012	0.3MetTrp: 0.3 ± 0.006	0.645MetTyr: 0.645 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.844AsnAla: 2.844 ± 0.02	0.498AsnCys: 0.498 ± 0.009	2.04AsnAsp: 2.04 ± 0.016	1.831AsnGlu: 1.831 ± 0.015	1.358AsnPhe: 1.358 ± 0.012	2.588AsnGly: 2.588 ± 0.021	0.907AsnHis: 0.907 ± 0.01	2.281AsnIle: 2.281 ± 0.016	1.376AsnLys: 1.376 ± 0.012	3.282AsnLeu: 3.282 ± 0.019	0.835AsnMet: 0.835 ± 0.01	1.38AsnAsn: 1.38 ± 0.015	2.26AsnPro: 2.26 ± 0.016	1.153AsnGln: 1.153 ± 0.012	1.779AsnArg: 1.779 ± 0.016	2.73AsnSer: 2.73 ± 0.02	2.206AsnThr: 2.206 ± 0.017	2.52AsnVal: 2.52 ± 0.018	0.569AsnTrp: 0.569 ± 0.009	0.984AsnTyr: 0.984 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.436ProAla: 4.436 ± 0.026	0.724ProCys: 0.724 ± 0.011	3.213ProAsp: 3.213 ± 0.019	3.364ProGlu: 3.364 ± 0.024	2.298ProPhe: 2.298 ± 0.018	3.403ProGly: 3.403 ± 0.022	1.497ProHis: 1.497 ± 0.014	2.928ProIle: 2.928 ± 0.02	2.439ProLys: 2.439 ± 0.019	5.259ProLeu: 5.259 ± 0.025	1.144ProMet: 1.144 ± 0.012	2.127ProAsn: 2.127 ± 0.017	5.504ProPro: 5.504 ± 0.053	2.115ProGln: 2.115 ± 0.019	3.298ProArg: 3.298 ± 0.02	6.762ProSer: 6.762 ± 0.041	4.08ProThr: 4.08 ± 0.027	3.782ProVal: 3.782 ± 0.024	0.826ProTrp: 0.826 ± 0.01	1.57ProTyr: 1.57 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	2.878GlnAla: 2.878 ± 0.018	0.645GlnCys: 0.645 ± 0.01	1.926GlnAsp: 1.926 ± 0.017	2.099GlnGlu: 2.099 ± 0.019	1.262GlnPhe: 1.262 ± 0.013	2.074GlnGly: 2.074 ± 0.018	1.008GlnHis: 1.008 ± 0.01	1.803GlnIle: 1.803 ± 0.016	1.643GlnLys: 1.643 ± 0.017	3.319GlnLeu: 3.319 ± 0.021	0.849GlnMet: 0.849 ± 0.011	1.336GlnAsn: 1.336 ± 0.012	2.037GlnPro: 2.037 ± 0.021	1.624GlnGln: 1.624 ± 0.02	2.377GlnArg: 2.377 ± 0.018	2.981GlnSer: 2.981 ± 0.02	2.206GlnThr: 2.206 ± 0.017	2.141GlnVal: 2.141 ± 0.017	0.626GlnTrp: 0.626 ± 0.008	1.149GlnTyr: 1.149 ± 0.011	0.0GlnXaa: 0.0 ± 0.0
Arg	4.186ArgAla: 4.186 ± 0.027	1.02ArgCys: 1.02 ± 0.01	3.129ArgAsp: 3.129 ± 0.023	3.336ArgGlu: 3.336 ± 0.026	2.214ArgPhe: 2.214 ± 0.018	3.304ArgGly: 3.304 ± 0.022	1.693ArgHis: 1.693 ± 0.015	3.164ArgIle: 3.164 ± 0.017	3.147ArgLys: 3.147 ± 0.023	5.714ArgLeu: 5.714 ± 0.028	1.384ArgMet: 1.384 ± 0.012	2.101ArgAsn: 2.101 ± 0.016	3.252ArgPro: 3.252 ± 0.025	2.256ArgGln: 2.256 ± 0.02	5.012ArgArg: 5.012 ± 0.038	4.907ArgSer: 4.907 ± 0.025	3.414ArgThr: 3.414 ± 0.019	3.62ArgVal: 3.62 ± 0.022	0.994ArgTrp: 0.994 ± 0.011	1.747ArgTyr: 1.747 ± 0.014	0.0ArgXaa: 0.0 ± 0.0
Ser	6.28SerAla: 6.28 ± 0.028	1.234SerCys: 1.234 ± 0.014	4.589SerAsp: 4.589 ± 0.029	4.01SerGlu: 4.01 ± 0.024	3.501SerPhe: 3.501 ± 0.02	5.148SerGly: 5.148 ± 0.029	2.285SerHis: 2.285 ± 0.017	4.542SerIle: 4.542 ± 0.023	3.552SerLys: 3.552 ± 0.021	8.612SerLeu: 8.612 ± 0.04	1.965SerMet: 1.965 ± 0.016	3.079SerAsn: 3.079 ± 0.017	5.793SerPro: 5.793 ± 0.041	3.131SerGln: 3.131 ± 0.021	5.116SerArg: 5.116 ± 0.027	9.93SerSer: 9.93 ± 0.06	5.965SerThr: 5.965 ± 0.032	5.362SerVal: 5.362 ± 0.028	1.272SerTrp: 1.272 ± 0.01	2.26SerTyr: 2.26 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	4.72ThrAla: 4.72 ± 0.026	0.944ThrCys: 0.944 ± 0.012	2.944ThrAsp: 2.944 ± 0.019	2.883ThrGlu: 2.883 ± 0.02	2.61ThrPhe: 2.61 ± 0.018	3.707ThrGly: 3.707 ± 0.023	1.501ThrHis: 1.501 ± 0.013	3.476ThrIle: 3.476 ± 0.022	2.459ThrLys: 2.459 ± 0.018	6.109ThrLeu: 6.109 ± 0.03	1.37ThrMet: 1.37 ± 0.012	2.058ThrAsn: 2.058 ± 0.016	4.195ThrPro: 4.195 ± 0.028	1.982ThrGln: 1.982 ± 0.016	3.32ThrArg: 3.32 ± 0.022	5.819ThrSer: 5.819 ± 0.033	4.198ThrThr: 4.198 ± 0.026	4.151ThrVal: 4.151 ± 0.025	0.903ThrTrp: 0.903 ± 0.009	1.686ThrTyr: 1.686 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	4.975ValAla: 4.975 ± 0.029	1.064ValCys: 1.064 ± 0.013	3.88ValAsp: 3.88 ± 0.021	3.751ValGlu: 3.751 ± 0.022	2.749ValPhe: 2.749 ± 0.017	3.763ValGly: 3.763 ± 0.024	1.698ValHis: 1.698 ± 0.015	3.422ValIle: 3.422 ± 0.019	2.908ValLys: 2.908 ± 0.02	6.425ValLeu: 6.425 ± 0.03	1.455ValMet: 1.455 ± 0.012	2.301ValAsn: 2.301 ± 0.017	3.935ValPro: 3.935 ± 0.024	2.431ValGln: 2.431 ± 0.021	3.368ValArg: 3.368 ± 0.022	5.106ValSer: 5.106 ± 0.029	3.798ValThr: 3.798 ± 0.023	4.685ValVal: 4.685 ± 0.029	1.037ValTrp: 1.037 ± 0.012	2.016ValTyr: 2.016 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	1.104TrpAla: 1.104 ± 0.012	0.317TrpCys: 0.317 ± 0.006	0.946TrpAsp: 0.946 ± 0.012	0.884TrpGlu: 0.884 ± 0.011	0.639TrpPhe: 0.639 ± 0.009	0.896TrpGly: 0.896 ± 0.011	0.421TrpHis: 0.421 ± 0.008	0.897TrpIle: 0.897 ± 0.01	0.885TrpLys: 0.885 ± 0.01	1.442TrpLeu: 1.442 ± 0.015	0.449TrpMet: 0.449 ± 0.007	0.684TrpAsn: 0.684 ± 0.01	0.639TrpPro: 0.639 ± 0.009	0.539TrpGln: 0.539 ± 0.008	1.119TrpArg: 1.119 ± 0.011	1.228TrpSer: 1.228 ± 0.013	1.038TrpThr: 1.038 ± 0.01	0.932TrpVal: 0.932 ± 0.01	0.318TrpTrp: 0.318 ± 0.007	0.491TrpTyr: 0.491 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.159TyrAla: 2.159 ± 0.017	0.494TyrCys: 0.494 ± 0.009	1.701TyrAsp: 1.701 ± 0.016	1.44TyrGlu: 1.44 ± 0.014	1.262TyrPhe: 1.262 ± 0.011	1.923TyrGly: 1.923 ± 0.018	0.909TyrHis: 0.909 ± 0.011	1.652TyrIle: 1.652 ± 0.015	1.108TyrLys: 1.108 ± 0.011	2.888TyrLeu: 2.888 ± 0.019	0.69TyrMet: 0.69 ± 0.009	1.142TyrAsn: 1.142 ± 0.01	1.664TyrPro: 1.664 ± 0.015	1.042TyrGln: 1.042 ± 0.011	1.742TyrArg: 1.742 ± 0.014	2.299TyrSer: 2.299 ± 0.016	1.788TyrThr: 1.788 ± 0.015	1.769TyrVal: 1.769 ± 0.015	0.448TyrTrp: 0.448 ± 0.008	0.975TyrTyr: 0.975 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 25522 proteins (8654150 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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