Amino acid dipepetide frequency for Faeces associated gemycircularvirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.546AlaAla: 1.546 ± 1.03
0.0AlaCys: 0.0 ± 0.0
4.637AlaAsp: 4.637 ± 0.93
1.546AlaGlu: 1.546 ± 1.03
1.546AlaPhe: 1.546 ± 1.03
4.637AlaGly: 4.637 ± 0.93
0.0AlaHis: 0.0 ± 0.0
3.091AlaIle: 3.091 ± 2.061
1.546AlaLys: 1.546 ± 1.131
3.091AlaLeu: 3.091 ± 2.061
1.546AlaMet: 1.546 ± 1.131
4.637AlaAsn: 4.637 ± 0.93
1.546AlaPro: 1.546 ± 1.03
4.637AlaGln: 4.637 ± 1.231
6.182AlaArg: 6.182 ± 0.2
3.091AlaSer: 3.091 ± 2.261
4.637AlaThr: 4.637 ± 1.231
4.637AlaVal: 4.637 ± 0.93
1.546AlaTrp: 1.546 ± 1.03
7.728AlaTyr: 7.728 ± 1.331
0.0AlaXaa: 0.0 ± 0.0
Cys
1.546CysAla: 1.546 ± 1.03
0.0CysCys: 0.0 ± 0.0
1.546CysAsp: 1.546 ± 1.03
0.0CysGlu: 0.0 ± 0.0
3.091CysPhe: 3.091 ± 2.261
1.546CysGly: 1.546 ± 1.03
0.0CysHis: 0.0 ± 0.0
3.091CysIle: 3.091 ± 2.061
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.546CysGln: 1.546 ± 1.03
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.546CysThr: 1.546 ± 1.03
1.546CysVal: 1.546 ± 1.03
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.091AspAla: 3.091 ± 2.061
0.0AspCys: 0.0 ± 0.0
6.182AspAsp: 6.182 ± 0.2
1.546AspGlu: 1.546 ± 1.131
3.091AspPhe: 3.091 ± 0.1
7.728AspGly: 7.728 ± 5.152
3.091AspHis: 3.091 ± 2.061
4.637AspIle: 4.637 ± 0.93
3.091AspLys: 3.091 ± 2.261
7.728AspLeu: 7.728 ± 3.492
1.546AspMet: 1.546 ± 1.03
1.546AspAsn: 1.546 ± 1.131
6.182AspPro: 6.182 ± 1.961
0.0AspGln: 0.0 ± 0.0
1.546AspArg: 1.546 ± 1.03
0.0AspSer: 0.0 ± 0.0
4.637AspThr: 4.637 ± 1.231
7.728AspVal: 7.728 ± 2.991
1.546AspTrp: 1.546 ± 1.131
3.091AspTyr: 3.091 ± 2.061
0.0AspXaa: 0.0 ± 0.0
Glu
1.546GluAla: 1.546 ± 1.131
3.091GluCys: 3.091 ± 2.061
1.546GluAsp: 1.546 ± 1.03
1.546GluGlu: 1.546 ± 1.03
3.091GluPhe: 3.091 ± 2.061
4.637GluGly: 4.637 ± 3.091
1.546GluHis: 1.546 ± 1.03
0.0GluIle: 0.0 ± 0.0
1.546GluLys: 1.546 ± 1.131
7.728GluLeu: 7.728 ± 5.152
0.0GluMet: 0.0 ± 0.75
1.546GluAsn: 1.546 ± 1.131
0.0GluPro: 0.0 ± 0.0
0.0GluGln: 0.0 ± 0.0
3.091GluArg: 3.091 ± 0.1
1.546GluSer: 1.546 ± 1.03
1.546GluThr: 1.546 ± 1.131
1.546GluVal: 1.546 ± 1.03
1.546GluTrp: 1.546 ± 1.03
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.546PheCys: 1.546 ± 1.03
6.182PheAsp: 6.182 ± 0.2
1.546PheGlu: 1.546 ± 1.03
3.091PhePhe: 3.091 ± 0.1
4.637PheGly: 4.637 ± 3.091
1.546PheHis: 1.546 ± 1.03
1.546PheIle: 1.546 ± 1.131
0.0PheLys: 0.0 ± 0.0
3.091PheLeu: 3.091 ± 0.1
1.546PheMet: 1.546 ± 1.131
3.091PheAsn: 3.091 ± 2.261
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
6.182PheArg: 6.182 ± 0.2
1.546PheSer: 1.546 ± 1.03
1.546PheThr: 1.546 ± 1.131
3.091PheVal: 3.091 ± 2.061
3.091PheTrp: 3.091 ± 0.1
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.182GlyAla: 6.182 ± 2.362
1.546GlyCys: 1.546 ± 1.03
7.728GlyAsp: 7.728 ± 2.991
3.091GlyGlu: 3.091 ± 2.061
1.546GlyPhe: 1.546 ± 1.131
12.365GlyGly: 12.365 ± 0.401
0.0GlyHis: 0.0 ± 0.0
7.728GlyIle: 7.728 ± 0.83
6.182GlyLys: 6.182 ± 1.961
4.637GlyLeu: 4.637 ± 0.93
1.546GlyMet: 1.546 ± 1.131
6.182GlyAsn: 6.182 ± 0.2
9.274GlyPro: 9.274 ± 2.462
4.637GlyGln: 4.637 ± 1.231
7.728GlyArg: 7.728 ± 2.991
4.637GlySer: 4.637 ± 1.231
7.728GlyThr: 7.728 ± 3.492
4.637GlyVal: 4.637 ± 0.93
3.091GlyTrp: 3.091 ± 2.061
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
4.637HisAla: 4.637 ± 3.091
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.546HisGlu: 1.546 ± 1.131
0.0HisPhe: 0.0 ± 0.0
1.546HisGly: 1.546 ± 1.03
0.0HisHis: 0.0 ± 0.0
1.546HisIle: 1.546 ± 1.03
0.0HisLys: 0.0 ± 0.0
3.091HisLeu: 3.091 ± 2.061
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
3.091HisPro: 3.091 ± 2.061
0.0HisGln: 0.0 ± 0.0
1.546HisArg: 1.546 ± 1.131
0.0HisSer: 0.0 ± 0.0
1.546HisThr: 1.546 ± 1.03
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.546IleAla: 1.546 ± 1.03
1.546IleCys: 1.546 ± 1.131
1.546IleAsp: 1.546 ± 1.131
1.546IleGlu: 1.546 ± 1.03
7.728IlePhe: 7.728 ± 0.83
6.182IleGly: 6.182 ± 1.961
0.0IleHis: 0.0 ± 0.0
3.091IleIle: 3.091 ± 2.061
6.182IleLys: 6.182 ± 0.2
4.637IleLeu: 4.637 ± 1.231
0.0IleMet: 0.0 ± 0.0
1.546IleAsn: 1.546 ± 1.131
1.546IlePro: 1.546 ± 1.131
1.546IleGln: 1.546 ± 1.131
1.546IleArg: 1.546 ± 1.131
1.546IleSer: 1.546 ± 1.131
1.546IleThr: 1.546 ± 1.03
1.546IleVal: 1.546 ± 1.03
1.546IleTrp: 1.546 ± 1.131
1.546IleTyr: 1.546 ± 1.03
0.0IleXaa: 0.0 ± 0.0
Lys
1.546LysAla: 1.546 ± 1.03
0.0LysCys: 0.0 ± 0.0
1.546LysAsp: 1.546 ± 1.03
1.546LysGlu: 1.546 ± 1.03
3.091LysPhe: 3.091 ± 2.061
3.091LysGly: 3.091 ± 2.261
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
9.274LysLys: 9.274 ± 4.623
1.546LysLeu: 1.546 ± 1.03
1.546LysMet: 1.546 ± 0.785
1.546LysAsn: 1.546 ± 1.131
3.091LysPro: 3.091 ± 2.061
1.546LysGln: 1.546 ± 1.03
10.819LysArg: 10.819 ± 7.915
1.546LysSer: 1.546 ± 1.131
1.546LysThr: 1.546 ± 1.03
0.0LysVal: 0.0 ± 0.0
1.546LysTrp: 1.546 ± 1.03
1.546LysTyr: 1.546 ± 1.03
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
1.546LeuCys: 1.546 ± 1.03
6.182LeuAsp: 6.182 ± 4.122
1.546LeuGlu: 1.546 ± 1.03
1.546LeuPhe: 1.546 ± 1.131
7.728LeuGly: 7.728 ± 2.991
3.091LeuHis: 3.091 ± 2.061
1.546LeuIle: 1.546 ± 1.131
0.0LeuLys: 0.0 ± 0.0
6.182LeuLeu: 6.182 ± 0.2
0.0LeuMet: 0.0 ± 0.0
3.091LeuAsn: 3.091 ± 2.261
1.546LeuPro: 1.546 ± 1.03
3.091LeuGln: 3.091 ± 2.261
6.182LeuArg: 6.182 ± 1.961
3.091LeuSer: 3.091 ± 2.061
6.182LeuThr: 6.182 ± 2.362
6.182LeuVal: 6.182 ± 0.2
1.546LeuTrp: 1.546 ± 1.03
6.182LeuTyr: 6.182 ± 2.362
0.0LeuXaa: 0.0 ± 0.0
Met
1.546MetAla: 1.546 ± 1.131
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.546MetGly: 1.546 ± 1.03
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.546MetLeu: 1.546 ± 1.131
0.0MetMet: 0.0 ± 0.0
1.546MetAsn: 1.546 ± 1.131
6.182MetPro: 6.182 ± 1.961
1.546MetGln: 1.546 ± 1.131
1.546MetArg: 1.546 ± 1.03
1.546MetSer: 1.546 ± 1.03
1.546MetThr: 1.546 ± 1.131
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.546AsnAla: 1.546 ± 1.131
1.546AsnCys: 1.546 ± 1.03
4.637AsnAsp: 4.637 ± 1.231
1.546AsnGlu: 1.546 ± 1.131
0.0AsnPhe: 0.0 ± 0.0
7.728AsnGly: 7.728 ± 5.653
1.546AsnHis: 1.546 ± 1.03
3.091AsnIle: 3.091 ± 2.261
0.0AsnLys: 0.0 ± 0.0
4.637AsnLeu: 4.637 ± 3.392
0.0AsnMet: 0.0 ± 0.0
1.546AsnAsn: 1.546 ± 1.131
0.0AsnPro: 0.0 ± 0.0
3.091AsnGln: 3.091 ± 2.261
1.546AsnArg: 1.546 ± 1.03
1.546AsnSer: 1.546 ± 1.131
7.728AsnThr: 7.728 ± 3.492
3.091AsnVal: 3.091 ± 2.061
1.546AsnTrp: 1.546 ± 1.03
1.546AsnTyr: 1.546 ± 1.03
0.0AsnXaa: 0.0 ± 0.0
Pro
7.728ProAla: 7.728 ± 0.83
0.0ProCys: 0.0 ± 0.0
1.546ProAsp: 1.546 ± 1.03
3.091ProGlu: 3.091 ± 2.061
0.0ProPhe: 0.0 ± 0.0
4.637ProGly: 4.637 ± 3.392
1.546ProHis: 1.546 ± 1.03
0.0ProIle: 0.0 ± 0.0
3.091ProLys: 3.091 ± 2.061
0.0ProLeu: 0.0 ± 0.0
0.0ProMet: 0.0 ± 0.0
1.546ProAsn: 1.546 ± 1.03
1.546ProPro: 1.546 ± 1.03
1.546ProGln: 1.546 ± 1.131
4.637ProArg: 4.637 ± 0.93
4.637ProSer: 4.637 ± 0.93
1.546ProThr: 1.546 ± 1.131
6.182ProVal: 6.182 ± 1.961
3.091ProTrp: 3.091 ± 0.1
1.546ProTyr: 1.546 ± 1.131
0.0ProXaa: 0.0 ± 0.0
Gln
3.091GlnAla: 3.091 ± 0.1
1.546GlnCys: 1.546 ± 1.03
1.546GlnAsp: 1.546 ± 1.131
1.546GlnGlu: 1.546 ± 1.03
0.0GlnPhe: 0.0 ± 0.0
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
1.546GlnLeu: 1.546 ± 1.131
3.091GlnMet: 3.091 ± 2.061
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
3.091GlnArg: 3.091 ± 2.261
4.637GlnSer: 4.637 ± 0.93
6.182GlnThr: 6.182 ± 4.523
1.546GlnVal: 1.546 ± 1.131
0.0GlnTrp: 0.0 ± 0.0
3.091GlnTyr: 3.091 ± 0.1
0.0GlnXaa: 0.0 ± 0.0
Arg
6.182ArgAla: 6.182 ± 0.2
0.0ArgCys: 0.0 ± 0.0
9.274ArgAsp: 9.274 ± 4.022
4.637ArgGlu: 4.637 ± 3.091
0.0ArgPhe: 0.0 ± 0.0
10.819ArgGly: 10.819 ± 1.431
1.546ArgHis: 1.546 ± 1.03
6.182ArgIle: 6.182 ± 4.523
4.637ArgLys: 4.637 ± 1.231
4.637ArgLeu: 4.637 ± 0.93
0.0ArgMet: 0.0 ± 0.0
3.091ArgAsn: 3.091 ± 2.261
7.728ArgPro: 7.728 ± 0.83
0.0ArgGln: 0.0 ± 0.0
3.091ArgArg: 3.091 ± 0.1
7.728ArgSer: 7.728 ± 0.83
1.546ArgThr: 1.546 ± 1.131
1.546ArgVal: 1.546 ± 1.131
0.0ArgTrp: 0.0 ± 0.0
7.728ArgTyr: 7.728 ± 3.492
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
3.091SerAsp: 3.091 ± 0.1
1.546SerGlu: 1.546 ± 1.03
3.091SerPhe: 3.091 ± 2.061
9.274SerGly: 9.274 ± 2.462
0.0SerHis: 0.0 ± 0.0
3.091SerIle: 3.091 ± 2.061
1.546SerLys: 1.546 ± 1.131
1.546SerLeu: 1.546 ± 1.03
1.546SerMet: 1.546 ± 1.03
4.637SerAsn: 4.637 ± 1.231
0.0SerPro: 0.0 ± 0.0
3.091SerGln: 3.091 ± 0.1
6.182SerArg: 6.182 ± 1.961
6.182SerSer: 6.182 ± 2.362
9.274SerThr: 9.274 ± 6.784
7.728SerVal: 7.728 ± 3.492
1.546SerTrp: 1.546 ± 1.03
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
6.182ThrAla: 6.182 ± 4.523
1.546ThrCys: 1.546 ± 1.131
1.546ThrAsp: 1.546 ± 1.131
4.637ThrGlu: 4.637 ± 1.231
1.546ThrPhe: 1.546 ± 1.131
6.182ThrGly: 6.182 ± 4.523
1.546ThrHis: 1.546 ± 1.03
7.728ThrIle: 7.728 ± 3.492
4.637ThrLys: 4.637 ± 1.231
3.091ThrLeu: 3.091 ± 0.1
1.546ThrMet: 1.546 ± 1.131
3.091ThrAsn: 3.091 ± 2.061
4.637ThrPro: 4.637 ± 3.392
0.0ThrGln: 0.0 ± 0.0
4.637ThrArg: 4.637 ± 1.231
10.819ThrSer: 10.819 ± 5.754
7.728ThrThr: 7.728 ± 5.653
3.091ThrVal: 3.091 ± 0.1
0.0ThrTrp: 0.0 ± 0.0
1.546ThrTyr: 1.546 ± 1.03
0.0ThrXaa: 0.0 ± 0.0
Val
3.091ValAla: 3.091 ± 0.1
1.546ValCys: 1.546 ± 1.03
6.182ValAsp: 6.182 ± 2.362
1.546ValGlu: 1.546 ± 1.03
6.182ValPhe: 6.182 ± 0.2
1.546ValGly: 1.546 ± 1.03
0.0ValHis: 0.0 ± 0.0
1.546ValIle: 1.546 ± 1.03
1.546ValLys: 1.546 ± 1.03
4.637ValLeu: 4.637 ± 0.93
1.546ValMet: 1.546 ± 1.03
7.728ValAsn: 7.728 ± 3.492
1.546ValPro: 1.546 ± 1.03
4.637ValGln: 4.637 ± 3.091
1.546ValArg: 1.546 ± 1.131
4.637ValSer: 4.637 ± 0.93
3.091ValThr: 3.091 ± 0.1
6.182ValVal: 6.182 ± 1.961
3.091ValTrp: 3.091 ± 2.061
3.091ValTyr: 3.091 ± 0.1
0.0ValXaa: 0.0 ± 0.0
Trp
3.091TrpAla: 3.091 ± 2.061
0.0TrpCys: 0.0 ± 0.0
1.546TrpAsp: 1.546 ± 1.03
1.546TrpGlu: 1.546 ± 1.03
3.091TrpPhe: 3.091 ± 0.1
1.546TrpGly: 1.546 ± 1.03
3.091TrpHis: 3.091 ± 2.261
0.0TrpIle: 0.0 ± 0.0
3.091TrpLys: 3.091 ± 2.061
3.091TrpLeu: 3.091 ± 2.061
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
3.091TrpArg: 3.091 ± 0.1
1.546TrpSer: 1.546 ± 1.03
0.0TrpThr: 0.0 ± 0.0
1.546TrpVal: 1.546 ± 1.131
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
7.728TyrAla: 7.728 ± 2.991
0.0TyrCys: 0.0 ± 0.0
1.546TyrAsp: 1.546 ± 1.131
3.091TyrGlu: 3.091 ± 2.061
1.546TyrPhe: 1.546 ± 1.03
3.091TyrGly: 3.091 ± 0.1
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
0.0TyrLeu: 0.0 ± 0.0
1.546TyrMet: 1.546 ± 1.131
1.546TyrAsn: 1.546 ± 1.131
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
6.182TyrArg: 6.182 ± 0.2
3.091TyrSer: 3.091 ± 2.261
4.637TyrThr: 4.637 ± 1.231
3.091TyrVal: 3.091 ± 0.1
1.546TyrTrp: 1.546 ± 1.131
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (648 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski