Amino acid dipepetide frequency for Undibacterium pigrum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.861AlaAla: 12.861 ± 0.13	1.222AlaCys: 1.222 ± 0.029	6.051AlaAsp: 6.051 ± 0.057	6.251AlaGlu: 6.251 ± 0.08	3.753AlaPhe: 3.753 ± 0.044	8.319AlaGly: 8.319 ± 0.083	2.187AlaHis: 2.187 ± 0.034	6.152AlaIle: 6.152 ± 0.064	4.821AlaLys: 4.821 ± 0.076	11.54AlaLeu: 11.54 ± 0.099	3.252AlaMet: 3.252 ± 0.05	3.855AlaAsn: 3.855 ± 0.043	4.09AlaPro: 4.09 ± 0.053	4.896AlaGln: 4.896 ± 0.054	5.711AlaArg: 5.711 ± 0.062	7.24AlaSer: 7.24 ± 0.073	5.54AlaThr: 5.54 ± 0.061	7.031AlaVal: 7.031 ± 0.066	1.47AlaTrp: 1.47 ± 0.033	2.998AlaTyr: 2.998 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	0.994CysAla: 0.994 ± 0.023	0.134CysCys: 0.134 ± 0.009	0.513CysAsp: 0.513 ± 0.017	0.474CysGlu: 0.474 ± 0.017	0.366CysPhe: 0.366 ± 0.013	0.832CysGly: 0.832 ± 0.023	0.273CysHis: 0.273 ± 0.013	0.526CysIle: 0.526 ± 0.017	0.372CysLys: 0.372 ± 0.016	1.036CysLeu: 1.036 ± 0.022	0.256CysMet: 0.256 ± 0.013	0.294CysAsn: 0.294 ± 0.014	0.399CysPro: 0.399 ± 0.016	0.357CysGln: 0.357 ± 0.014	0.44CysArg: 0.44 ± 0.016	0.628CysSer: 0.628 ± 0.023	0.476CysThr: 0.476 ± 0.021	0.608CysVal: 0.608 ± 0.019	0.136CysTrp: 0.136 ± 0.009	0.263CysTyr: 0.263 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	5.874AspAla: 5.874 ± 0.061	0.495AspCys: 0.495 ± 0.016	2.731AspAsp: 2.731 ± 0.04	3.163AspGlu: 3.163 ± 0.045	2.414AspPhe: 2.414 ± 0.037	4.029AspGly: 4.029 ± 0.052	1.019AspHis: 1.019 ± 0.026	3.377AspIle: 3.377 ± 0.043	2.823AspLys: 2.823 ± 0.043	5.252AspLeu: 5.252 ± 0.064	1.464AspMet: 1.464 ± 0.031	1.855AspAsn: 1.855 ± 0.033	2.134AspPro: 2.134 ± 0.035	1.978AspGln: 1.978 ± 0.032	2.294AspArg: 2.294 ± 0.035	2.799AspSer: 2.799 ± 0.042	2.7AspThr: 2.7 ± 0.041	3.597AspVal: 3.597 ± 0.046	0.924AspTrp: 0.924 ± 0.025	1.741AspTyr: 1.741 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	5.726GluAla: 5.726 ± 0.069	0.396GluCys: 0.396 ± 0.013	2.375GluAsp: 2.375 ± 0.033	3.042GluGlu: 3.042 ± 0.045	2.171GluPhe: 2.171 ± 0.036	3.074GluGly: 3.074 ± 0.042	1.354GluHis: 1.354 ± 0.029	3.4GluIle: 3.4 ± 0.048	3.331GluLys: 3.331 ± 0.044	5.89GluLeu: 5.89 ± 0.064	1.517GluMet: 1.517 ± 0.032	2.175GluAsn: 2.175 ± 0.037	1.798GluPro: 1.798 ± 0.036	3.168GluGln: 3.168 ± 0.053	3.291GluArg: 3.291 ± 0.046	2.746GluSer: 2.746 ± 0.034	2.716GluThr: 2.716 ± 0.038	3.82GluVal: 3.82 ± 0.049	0.697GluTrp: 0.697 ± 0.017	1.412GluTyr: 1.412 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	4.229PheAla: 4.229 ± 0.048	0.479PheCys: 0.479 ± 0.015	2.458PheAsp: 2.458 ± 0.041	2.074PheGlu: 2.074 ± 0.034	1.696PhePhe: 1.696 ± 0.036	3.113PheGly: 3.113 ± 0.044	0.794PheHis: 0.794 ± 0.02	2.147PheIle: 2.147 ± 0.037	1.694PheLys: 1.694 ± 0.035	3.441PheLeu: 3.441 ± 0.051	0.95PheMet: 0.95 ± 0.025	1.57PheAsn: 1.57 ± 0.033	1.612PhePro: 1.612 ± 0.03	1.347PheGln: 1.347 ± 0.028	1.772PheArg: 1.772 ± 0.033	3.041PheSer: 3.041 ± 0.042	2.088PheThr: 2.088 ± 0.036	2.57PheVal: 2.57 ± 0.041	0.58PheTrp: 0.58 ± 0.022	1.177PheTyr: 1.177 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	6.221GlyAla: 6.221 ± 0.077	0.684GlyCys: 0.684 ± 0.023	3.542GlyAsp: 3.542 ± 0.047	3.683GlyGlu: 3.683 ± 0.048	3.174GlyPhe: 3.174 ± 0.045	5.337GlyGly: 5.337 ± 0.083	1.585GlyHis: 1.585 ± 0.032	4.508GlyIle: 4.508 ± 0.045	4.651GlyLys: 4.651 ± 0.046	7.528GlyLeu: 7.528 ± 0.073	2.293GlyMet: 2.293 ± 0.039	2.919GlyAsn: 2.919 ± 0.054	2.04GlyPro: 2.04 ± 0.033	3.051GlyGln: 3.051 ± 0.047	3.587GlyArg: 3.587 ± 0.045	4.503GlySer: 4.503 ± 0.053	3.857GlyThr: 3.857 ± 0.065	5.07GlyVal: 5.07 ± 0.06	1.131GlyTrp: 1.131 ± 0.027	2.27GlyTyr: 2.27 ± 0.037	0.0GlyXaa: 0.0 ± 0.0
His	2.556HisAla: 2.556 ± 0.041	0.269HisCys: 0.269 ± 0.012	1.164HisAsp: 1.164 ± 0.024	1.179HisGlu: 1.179 ± 0.026	1.051HisPhe: 1.051 ± 0.021	1.817HisGly: 1.817 ± 0.032	0.648HisHis: 0.648 ± 0.02	1.292HisIle: 1.292 ± 0.025	0.807HisLys: 0.807 ± 0.018	2.364HisLeu: 2.364 ± 0.047	0.569HisMet: 0.569 ± 0.02	0.603HisAsn: 0.603 ± 0.017	1.234HisPro: 1.234 ± 0.027	0.95HisGln: 0.95 ± 0.023	1.027HisArg: 1.027 ± 0.026	1.185HisSer: 1.185 ± 0.027	1.075HisThr: 1.075 ± 0.023	1.411HisVal: 1.411 ± 0.034	0.356HisTrp: 0.356 ± 0.013	0.74HisTyr: 0.74 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	7.021IleAla: 7.021 ± 0.059	0.615IleCys: 0.615 ± 0.02	3.362IleAsp: 3.362 ± 0.039	3.146IleGlu: 3.146 ± 0.04	2.016IlePhe: 2.016 ± 0.036	4.135IleGly: 4.135 ± 0.052	1.134IleHis: 1.134 ± 0.027	2.893IleIle: 2.893 ± 0.043	2.678IleLys: 2.678 ± 0.039	5.184IleLeu: 5.184 ± 0.056	1.22IleMet: 1.22 ± 0.03	2.353IleAsn: 2.353 ± 0.042	2.555IlePro: 2.555 ± 0.041	1.899IleGln: 1.899 ± 0.033	2.872IleArg: 2.872 ± 0.047	4.21IleSer: 4.21 ± 0.056	3.18IleThr: 3.18 ± 0.046	3.802IleVal: 3.802 ± 0.052	0.67IleTrp: 0.67 ± 0.018	1.436IleTyr: 1.436 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	4.851LysAla: 4.851 ± 0.06	0.255LysCys: 0.255 ± 0.011	2.513LysAsp: 2.513 ± 0.04	2.619LysGlu: 2.619 ± 0.042	1.539LysPhe: 1.539 ± 0.031	2.681LysGly: 2.681 ± 0.04	1.028LysHis: 1.028 ± 0.025	2.829LysIle: 2.829 ± 0.043	2.731LysLys: 2.731 ± 0.047	5.394LysLeu: 5.394 ± 0.054	1.439LysMet: 1.439 ± 0.028	2.202LysAsn: 2.202 ± 0.042	2.606LysPro: 2.606 ± 0.04	2.327LysGln: 2.327 ± 0.037	2.521LysArg: 2.521 ± 0.038	2.822LysSer: 2.822 ± 0.039	2.918LysThr: 2.918 ± 0.041	3.1LysVal: 3.1 ± 0.044	0.511LysTrp: 0.511 ± 0.017	1.096LysTyr: 1.096 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	12.347LeuAla: 12.347 ± 0.112	1.049LeuCys: 1.049 ± 0.028	5.541LeuAsp: 5.541 ± 0.059	5.445LeuGlu: 5.445 ± 0.053	3.8LeuPhe: 3.8 ± 0.056	7.202LeuGly: 7.202 ± 0.062	2.483LeuHis: 2.483 ± 0.04	5.478LeuIle: 5.478 ± 0.065	4.811LeuLys: 4.811 ± 0.057	11.364LeuLeu: 11.364 ± 0.116	2.627LeuMet: 2.627 ± 0.041	3.905LeuAsn: 3.905 ± 0.054	5.713LeuPro: 5.713 ± 0.067	5.133LeuGln: 5.133 ± 0.069	6.142LeuArg: 6.142 ± 0.075	7.384LeuSer: 7.384 ± 0.07	5.568LeuThr: 5.568 ± 0.054	6.47LeuVal: 6.47 ± 0.057	1.161LeuTrp: 1.161 ± 0.024	2.466LeuTyr: 2.466 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.78MetAla: 2.78 ± 0.043	0.175MetCys: 0.175 ± 0.009	1.266MetAsp: 1.266 ± 0.027	1.279MetGlu: 1.279 ± 0.028	0.843MetPhe: 0.843 ± 0.027	1.763MetGly: 1.763 ± 0.036	0.686MetHis: 0.686 ± 0.019	1.286MetIle: 1.286 ± 0.028	1.363MetLys: 1.363 ± 0.024	3.139MetLeu: 3.139 ± 0.044	0.757MetMet: 0.757 ± 0.02	1.116MetAsn: 1.116 ± 0.023	1.445MetPro: 1.445 ± 0.028	1.661MetGln: 1.661 ± 0.035	1.612MetArg: 1.612 ± 0.027	1.85MetSer: 1.85 ± 0.032	1.61MetThr: 1.61 ± 0.028	1.648MetVal: 1.648 ± 0.033	0.215MetTrp: 0.215 ± 0.011	0.519MetTyr: 0.519 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.943AsnAla: 3.943 ± 0.051	0.355AsnCys: 0.355 ± 0.015	1.828AsnAsp: 1.828 ± 0.035	1.798AsnGlu: 1.798 ± 0.036	1.535AsnPhe: 1.535 ± 0.029	2.893AsnGly: 2.893 ± 0.043	0.735AsnHis: 0.735 ± 0.02	2.27AsnIle: 2.27 ± 0.04	1.811AsnLys: 1.811 ± 0.031	3.962AsnLeu: 3.962 ± 0.051	0.941AsnMet: 0.941 ± 0.027	1.492AsnAsn: 1.492 ± 0.032	2.053AsnPro: 2.053 ± 0.037	1.53AsnGln: 1.53 ± 0.033	1.762AsnArg: 1.762 ± 0.029	2.213AsnSer: 2.213 ± 0.045	2.195AsnThr: 2.195 ± 0.04	2.375AsnVal: 2.375 ± 0.04	0.606AsnTrp: 0.606 ± 0.018	1.186AsnTyr: 1.186 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	5.552ProAla: 5.552 ± 0.072	0.325ProCys: 0.325 ± 0.013	2.882ProAsp: 2.882 ± 0.038	3.129ProGlu: 3.129 ± 0.04	1.58ProPhe: 1.58 ± 0.029	3.47ProGly: 3.47 ± 0.049	0.932ProHis: 0.932 ± 0.02	1.86ProIle: 1.86 ± 0.03	1.684ProLys: 1.684 ± 0.035	4.227ProLeu: 4.227 ± 0.054	1.056ProMet: 1.056 ± 0.026	1.341ProAsn: 1.341 ± 0.03	1.703ProPro: 1.703 ± 0.04	1.895ProGln: 1.895 ± 0.033	1.926ProArg: 1.926 ± 0.037	2.347ProSer: 2.347 ± 0.038	2.034ProThr: 2.034 ± 0.043	3.934ProVal: 3.934 ± 0.059	0.566ProTrp: 0.566 ± 0.019	1.262ProTyr: 1.262 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	5.7GlnAla: 5.7 ± 0.076	0.32GlnCys: 0.32 ± 0.013	2.046GlnAsp: 2.046 ± 0.035	2.229GlnGlu: 2.229 ± 0.04	1.733GlnPhe: 1.733 ± 0.031	2.949GlnGly: 2.949 ± 0.042	1.222GlnHis: 1.222 ± 0.031	2.562GlnIle: 2.562 ± 0.042	2.064GlnLys: 2.064 ± 0.034	4.804GlnLeu: 4.804 ± 0.053	1.142GlnMet: 1.142 ± 0.024	1.554GlnAsn: 1.554 ± 0.031	1.799GlnPro: 1.799 ± 0.036	2.748GlnGln: 2.748 ± 0.053	2.743GlnArg: 2.743 ± 0.039	2.516GlnSer: 2.516 ± 0.04	2.473GlnThr: 2.473 ± 0.04	3.068GlnVal: 3.068 ± 0.04	0.579GlnTrp: 0.579 ± 0.016	1.089GlnTyr: 1.089 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	4.857ArgAla: 4.857 ± 0.056	0.424ArgCys: 0.424 ± 0.015	2.828ArgAsp: 2.828 ± 0.042	3.155ArgGlu: 3.155 ± 0.042	2.242ArgPhe: 2.242 ± 0.04	3.087ArgGly: 3.087 ± 0.043	1.406ArgHis: 1.406 ± 0.027	3.247ArgIle: 3.247 ± 0.047	2.493ArgLys: 2.493 ± 0.041	6.078ArgLeu: 6.078 ± 0.065	1.56ArgMet: 1.56 ± 0.031	2.031ArgAsn: 2.031 ± 0.034	2.084ArgPro: 2.084 ± 0.034	2.765ArgGln: 2.765 ± 0.044	2.887ArgArg: 2.887 ± 0.045	3.091ArgSer: 3.091 ± 0.04	2.44ArgThr: 2.44 ± 0.033	3.334ArgVal: 3.334 ± 0.043	0.779ArgTrp: 0.779 ± 0.019	1.745ArgTyr: 1.745 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.43SerAla: 6.43 ± 0.072	0.573SerCys: 0.573 ± 0.018	3.058SerAsp: 3.058 ± 0.043	3.011SerGlu: 3.011 ± 0.039	2.713SerPhe: 2.713 ± 0.036	5.153SerGly: 5.153 ± 0.064	1.378SerHis: 1.378 ± 0.029	3.675SerIle: 3.675 ± 0.055	3.139SerLys: 3.139 ± 0.044	7.229SerLeu: 7.229 ± 0.068	1.795SerMet: 1.795 ± 0.032	2.449SerAsn: 2.449 ± 0.042	2.65SerPro: 2.65 ± 0.04	2.474SerGln: 2.474 ± 0.039	3.157SerArg: 3.157 ± 0.042	4.298SerSer: 4.298 ± 0.071	3.355SerThr: 3.355 ± 0.055	4.062SerVal: 4.062 ± 0.048	0.877SerTrp: 0.877 ± 0.023	1.918SerTyr: 1.918 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	6.05ThrAla: 6.05 ± 0.066	0.468ThrCys: 0.468 ± 0.017	2.754ThrAsp: 2.754 ± 0.035	2.878ThrGlu: 2.878 ± 0.044	1.635ThrPhe: 1.635 ± 0.03	4.627ThrGly: 4.627 ± 0.069	1.107ThrHis: 1.107 ± 0.027	2.95ThrIle: 2.95 ± 0.045	1.807ThrLys: 1.807 ± 0.035	5.661ThrLeu: 5.661 ± 0.056	1.272ThrMet: 1.272 ± 0.026	1.697ThrAsn: 1.697 ± 0.037	3.032ThrPro: 3.032 ± 0.051	2.157ThrGln: 2.157 ± 0.036	2.702ThrArg: 2.702 ± 0.039	3.413ThrSer: 3.413 ± 0.051	3.189ThrThr: 3.189 ± 0.054	3.905ThrVal: 3.905 ± 0.048	0.658ThrTrp: 0.658 ± 0.019	1.462ThrTyr: 1.462 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	7.443ValAla: 7.443 ± 0.074	0.68ValCys: 0.68 ± 0.019	3.637ValAsp: 3.637 ± 0.045	3.642ValGlu: 3.642 ± 0.041	2.693ValPhe: 2.693 ± 0.039	4.262ValGly: 4.262 ± 0.053	1.395ValHis: 1.395 ± 0.03	3.934ValIle: 3.934 ± 0.051	3.068ValLys: 3.068 ± 0.047	7.068ValLeu: 7.068 ± 0.07	1.87ValMet: 1.87 ± 0.036	2.69ValAsn: 2.69 ± 0.041	2.887ValPro: 2.887 ± 0.044	2.65ValGln: 2.65 ± 0.037	3.479ValArg: 3.479 ± 0.043	4.589ValSer: 4.589 ± 0.055	3.891ValThr: 3.891 ± 0.056	4.947ValVal: 4.947 ± 0.06	0.816ValTrp: 0.816 ± 0.023	1.708ValTyr: 1.708 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	1.01TrpAla: 1.01 ± 0.024	0.148TrpCys: 0.148 ± 0.008	0.646TrpAsp: 0.646 ± 0.021	0.56TrpGlu: 0.56 ± 0.019	0.536TrpPhe: 0.536 ± 0.019	0.779TrpGly: 0.779 ± 0.019	0.359TrpHis: 0.359 ± 0.014	0.748TrpIle: 0.748 ± 0.022	0.642TrpLys: 0.642 ± 0.02	1.786TrpLeu: 1.786 ± 0.039	0.433TrpMet: 0.433 ± 0.017	0.513TrpAsn: 0.513 ± 0.017	0.528TrpPro: 0.528 ± 0.019	0.937TrpGln: 0.937 ± 0.023	0.905TrpArg: 0.905 ± 0.023	0.797TrpSer: 0.797 ± 0.024	0.648TrpThr: 0.648 ± 0.02	0.828TrpVal: 0.828 ± 0.024	0.234TrpTrp: 0.234 ± 0.012	0.398TrpTyr: 0.398 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.797TyrAla: 2.797 ± 0.043	0.311TyrCys: 0.311 ± 0.013	1.465TyrAsp: 1.465 ± 0.03	1.341TyrGlu: 1.341 ± 0.027	1.342TyrPhe: 1.342 ± 0.028	2.113TyrGly: 2.113 ± 0.033	0.57TyrHis: 0.57 ± 0.015	1.247TyrIle: 1.247 ± 0.028	1.192TyrLys: 1.192 ± 0.027	3.142TyrLeu: 3.142 ± 0.043	0.6TyrMet: 0.6 ± 0.018	0.87TyrAsn: 0.87 ± 0.023	1.341TyrPro: 1.341 ± 0.028	1.418TyrGln: 1.418 ± 0.029	1.703TyrArg: 1.703 ± 0.032	1.72TyrSer: 1.72 ± 0.036	1.474TyrThr: 1.474 ± 0.035	1.77TyrVal: 1.77 ± 0.032	0.468TyrTrp: 0.468 ± 0.016	0.846TyrTyr: 0.846 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5704 proteins (1883445 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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