Amino acid dipepetide frequency for Tea plant line pattern virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.486AlaAla: 4.486 ± 1.258
0.897AlaCys: 0.897 ± 0.647
1.795AlaAsp: 1.795 ± 0.791
3.14AlaGlu: 3.14 ± 1.151
4.486AlaPhe: 4.486 ± 0.925
3.589AlaGly: 3.589 ± 1.166
1.346AlaHis: 1.346 ± 0.528
4.038AlaIle: 4.038 ± 1.539
2.692AlaLys: 2.692 ± 1.098
6.729AlaLeu: 6.729 ± 2.384
1.346AlaMet: 1.346 ± 0.944
2.692AlaAsn: 2.692 ± 1.496
1.346AlaPro: 1.346 ± 1.058
1.795AlaGln: 1.795 ± 0.823
2.692AlaArg: 2.692 ± 0.723
2.692AlaSer: 2.692 ± 0.768
5.384AlaThr: 5.384 ± 1.246
3.589AlaVal: 3.589 ± 2.034
0.897AlaTrp: 0.897 ± 0.36
0.897AlaTyr: 0.897 ± 0.7
0.0AlaXaa: 0.0 ± 0.0
Cys
0.449CysAla: 0.449 ± 0.315
0.897CysCys: 0.897 ± 0.629
1.795CysAsp: 1.795 ± 0.694
0.897CysGlu: 0.897 ± 0.629
1.795CysPhe: 1.795 ± 0.719
0.897CysGly: 0.897 ± 0.629
1.795CysHis: 1.795 ± 0.533
0.897CysIle: 0.897 ± 0.36
0.449CysLys: 0.449 ± 0.315
1.795CysLeu: 1.795 ± 0.533
0.449CysMet: 0.449 ± 0.422
0.897CysAsn: 0.897 ± 0.36
1.795CysPro: 1.795 ± 0.855
0.0CysGln: 0.0 ± 0.0
1.795CysArg: 1.795 ± 0.426
1.795CysSer: 1.795 ± 0.694
0.897CysThr: 0.897 ± 0.844
1.795CysVal: 1.795 ± 0.426
0.0CysTrp: 0.0 ± 0.0
0.897CysTyr: 0.897 ± 0.7
0.0CysXaa: 0.0 ± 0.0
Asp
6.281AspAla: 6.281 ± 1.289
0.449AspCys: 0.449 ± 0.422
3.589AspAsp: 3.589 ± 2.177
4.038AspGlu: 4.038 ± 1.131
2.692AspPhe: 2.692 ± 1.055
2.243AspGly: 2.243 ± 1.191
1.795AspHis: 1.795 ± 1.258
3.589AspIle: 3.589 ± 1.05
3.14AspLys: 3.14 ± 1.153
8.524AspLeu: 8.524 ± 2.388
3.14AspMet: 3.14 ± 0.326
1.346AspAsn: 1.346 ± 0.944
0.897AspPro: 0.897 ± 0.36
1.346AspGln: 1.346 ± 0.944
2.692AspArg: 2.692 ± 1.055
6.281AspSer: 6.281 ± 3.202
2.692AspThr: 2.692 ± 1.43
6.281AspVal: 6.281 ± 1.722
0.897AspTrp: 0.897 ± 0.844
2.243AspTyr: 2.243 ± 1.055
0.0AspXaa: 0.0 ± 0.0
Glu
4.935GluAla: 4.935 ± 0.568
1.795GluCys: 1.795 ± 0.855
4.038GluAsp: 4.038 ± 0.715
3.14GluGlu: 3.14 ± 0.605
3.589GluPhe: 3.589 ± 1.067
2.692GluGly: 2.692 ± 0.548
0.449GluHis: 0.449 ± 0.422
4.038GluIle: 4.038 ± 1.944
8.075GluLys: 8.075 ± 1.606
4.486GluLeu: 4.486 ± 1.258
0.449GluMet: 0.449 ± 0.422
2.692GluAsn: 2.692 ± 0.362
2.243GluPro: 2.243 ± 1.055
2.243GluGln: 2.243 ± 0.503
4.486GluArg: 4.486 ± 0.704
4.038GluSer: 4.038 ± 1.458
2.692GluThr: 2.692 ± 0.768
4.486GluVal: 4.486 ± 1.182
0.449GluTrp: 0.449 ± 0.633
1.346GluTyr: 1.346 ± 0.503
0.0GluXaa: 0.0 ± 0.0
Phe
1.346PheAla: 1.346 ± 0.503
0.449PheCys: 0.449 ± 0.315
3.589PheAsp: 3.589 ± 1.768
4.038PheGlu: 4.038 ± 1.534
1.795PhePhe: 1.795 ± 1.122
2.243PheGly: 2.243 ± 1.045
1.346PheHis: 1.346 ± 0.718
4.038PheIle: 4.038 ± 1.044
4.038PheLys: 4.038 ± 2.183
4.935PheLeu: 4.935 ± 3.207
1.795PheMet: 1.795 ± 0.969
0.897PheAsn: 0.897 ± 0.36
4.935PhePro: 4.935 ± 1.902
1.795PheGln: 1.795 ± 0.719
3.589PheArg: 3.589 ± 0.978
6.281PheSer: 6.281 ± 1.445
1.795PheThr: 1.795 ± 0.426
3.589PheVal: 3.589 ± 1.173
0.449PheTrp: 0.449 ± 0.422
0.897PheTyr: 0.897 ± 0.36
0.0PheXaa: 0.0 ± 0.0
Gly
2.243GlyAla: 2.243 ± 1.013
2.692GlyCys: 2.692 ± 0.548
3.14GlyAsp: 3.14 ± 0.722
2.243GlyGlu: 2.243 ± 1.338
3.14GlyPhe: 3.14 ± 0.722
1.346GlyGly: 1.346 ± 0.944
0.449GlyHis: 0.449 ± 0.816
1.346GlyIle: 1.346 ± 0.528
4.935GlyLys: 4.935 ± 1.208
3.14GlyLeu: 3.14 ± 1.665
0.0GlyMet: 0.0 ± 0.0
2.243GlyAsn: 2.243 ± 1.082
1.346GlyPro: 1.346 ± 0.503
1.795GlyGln: 1.795 ± 2.534
3.589GlyArg: 3.589 ± 0.757
4.038GlySer: 4.038 ± 1.933
3.589GlyThr: 3.589 ± 1.667
3.14GlyVal: 3.14 ± 2.202
0.449GlyTrp: 0.449 ± 0.422
0.449GlyTyr: 0.449 ± 0.315
0.0GlyXaa: 0.0 ± 0.0
His
0.897HisAla: 0.897 ± 0.7
0.897HisCys: 0.897 ± 0.36
0.897HisAsp: 0.897 ± 0.844
1.795HisGlu: 1.795 ± 0.692
2.243HisPhe: 2.243 ± 0.846
1.346HisGly: 1.346 ± 0.528
0.897HisHis: 0.897 ± 0.844
2.243HisIle: 2.243 ± 0.456
0.897HisLys: 0.897 ± 0.629
0.897HisLeu: 0.897 ± 0.629
0.449HisMet: 0.449 ± 0.422
1.795HisAsn: 1.795 ± 0.791
2.243HisPro: 2.243 ± 1.573
0.897HisGln: 0.897 ± 0.36
1.346HisArg: 1.346 ± 0.944
3.14HisSer: 3.14 ± 0.503
0.449HisThr: 0.449 ± 0.633
2.243HisVal: 2.243 ± 0.456
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.897IleAla: 0.897 ± 0.629
0.897IleCys: 0.897 ± 0.795
4.038IleAsp: 4.038 ± 1.541
2.692IleGlu: 2.692 ± 0.362
1.795IlePhe: 1.795 ± 0.719
3.589IleGly: 3.589 ± 0.949
0.897IleHis: 0.897 ± 0.36
2.243IleIle: 2.243 ± 0.659
4.038IleLys: 4.038 ± 1.676
5.384IleLeu: 5.384 ± 1.837
0.897IleMet: 0.897 ± 0.629
4.038IleAsn: 4.038 ± 2.848
4.486IlePro: 4.486 ± 1.542
1.795IleGln: 1.795 ± 0.719
1.346IleArg: 1.346 ± 0.944
6.281IleSer: 6.281 ± 2.198
2.692IleThr: 2.692 ± 0.723
3.589IleVal: 3.589 ± 1.998
0.449IleTrp: 0.449 ± 0.633
1.346IleTyr: 1.346 ± 0.944
0.0IleXaa: 0.0 ± 0.0
Lys
5.832LysAla: 5.832 ± 1.885
0.897LysCys: 0.897 ± 0.629
2.692LysAsp: 2.692 ± 1.22
4.486LysGlu: 4.486 ± 2.012
4.935LysPhe: 4.935 ± 1.902
2.243LysGly: 2.243 ± 1.045
1.346LysHis: 1.346 ± 0.944
4.935LysIle: 4.935 ± 1.505
3.589LysLys: 3.589 ± 1.05
7.178LysLeu: 7.178 ± 2.667
1.795LysMet: 1.795 ± 1.4
2.692LysAsn: 2.692 ± 1.152
1.346LysPro: 1.346 ± 0.555
3.14LysGln: 3.14 ± 1.252
4.038LysArg: 4.038 ± 1.166
4.486LysSer: 4.486 ± 1.713
4.486LysThr: 4.486 ± 2.01
5.384LysVal: 5.384 ± 1.786
0.449LysTrp: 0.449 ± 0.315
0.449LysTyr: 0.449 ± 0.422
0.0LysXaa: 0.0 ± 0.0
Leu
4.486LeuAla: 4.486 ± 1.824
3.589LeuCys: 3.589 ± 1.438
7.627LeuAsp: 7.627 ± 2.369
6.729LeuGlu: 6.729 ± 1.258
4.038LeuPhe: 4.038 ± 1.427
4.038LeuGly: 4.038 ± 0.774
1.795LeuHis: 1.795 ± 0.692
1.795LeuIle: 1.795 ± 0.719
7.178LeuLys: 7.178 ± 1.478
7.627LeuLeu: 7.627 ± 0.995
2.692LeuMet: 2.692 ± 0.723
3.589LeuAsn: 3.589 ± 2.043
3.589LeuPro: 3.589 ± 0.929
2.243LeuGln: 2.243 ± 0.832
5.384LeuArg: 5.384 ± 1.516
11.664LeuSer: 11.664 ± 4.034
8.075LeuThr: 8.075 ± 2.08
5.832LeuVal: 5.832 ± 0.9
0.897LeuTrp: 0.897 ± 0.795
2.243LeuTyr: 2.243 ± 0.503
0.0LeuXaa: 0.0 ± 0.0
Met
1.346MetAla: 1.346 ± 0.715
0.449MetCys: 0.449 ± 0.816
2.243MetAsp: 2.243 ± 1.082
2.243MetGlu: 2.243 ± 1.03
0.449MetPhe: 0.449 ± 0.816
0.897MetGly: 0.897 ± 0.36
0.449MetHis: 0.449 ± 0.315
2.243MetIle: 2.243 ± 0.503
0.897MetLys: 0.897 ± 0.36
2.692MetLeu: 2.692 ± 0.623
1.346MetMet: 1.346 ± 0.75
1.346MetAsn: 1.346 ± 0.528
0.449MetPro: 0.449 ± 0.422
0.897MetGln: 0.897 ± 0.7
2.243MetArg: 2.243 ± 1.082
3.14MetSer: 3.14 ± 0.735
0.897MetThr: 0.897 ± 0.619
0.897MetVal: 0.897 ± 0.36
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.589AsnAla: 3.589 ± 0.332
0.449AsnCys: 0.449 ± 0.422
2.692AsnAsp: 2.692 ± 0.667
1.346AsnGlu: 1.346 ± 0.715
1.795AsnPhe: 1.795 ± 0.823
3.14AsnGly: 3.14 ± 1.545
1.795AsnHis: 1.795 ± 0.426
1.795AsnIle: 1.795 ± 1.4
5.832AsnLys: 5.832 ± 2.218
3.589AsnLeu: 3.589 ± 1.647
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
2.243AsnPro: 2.243 ± 1.191
1.795AsnGln: 1.795 ± 0.426
2.243AsnArg: 2.243 ± 1.561
5.384AsnSer: 5.384 ± 1.297
2.243AsnThr: 2.243 ± 0.602
4.935AsnVal: 4.935 ± 1.19
0.897AsnTrp: 0.897 ± 0.7
0.449AsnTyr: 0.449 ± 0.315
0.0AsnXaa: 0.0 ± 0.0
Pro
1.346ProAla: 1.346 ± 0.718
0.449ProCys: 0.449 ± 0.315
4.486ProAsp: 4.486 ± 1.258
1.346ProGlu: 1.346 ± 0.715
2.243ProPhe: 2.243 ± 1.055
1.346ProGly: 1.346 ± 0.503
1.795ProHis: 1.795 ± 0.719
3.589ProIle: 3.589 ± 1.721
2.243ProLys: 2.243 ± 1.616
4.486ProLeu: 4.486 ± 1.344
1.346ProMet: 1.346 ± 0.718
2.692ProAsn: 2.692 ± 0.623
0.0ProPro: 0.0 ± 0.0
0.897ProGln: 0.897 ± 0.629
1.346ProArg: 1.346 ± 0.977
3.14ProSer: 3.14 ± 1.253
1.346ProThr: 1.346 ± 0.75
2.692ProVal: 2.692 ± 1.383
0.449ProTrp: 0.449 ± 0.315
0.897ProTyr: 0.897 ± 0.647
0.0ProXaa: 0.0 ± 0.0
Gln
2.243GlnAla: 2.243 ± 1.231
0.897GlnCys: 0.897 ± 0.36
0.897GlnAsp: 0.897 ± 0.36
0.449GlnGlu: 0.449 ± 0.315
1.346GlnPhe: 1.346 ± 1.663
0.897GlnGly: 0.897 ± 0.36
0.897GlnHis: 0.897 ± 0.629
1.346GlnIle: 1.346 ± 0.944
0.897GlnLys: 0.897 ± 0.619
4.038GlnLeu: 4.038 ± 1.395
0.897GlnMet: 0.897 ± 0.507
2.692GlnAsn: 2.692 ± 1.22
0.897GlnPro: 0.897 ± 0.36
1.795GlnGln: 1.795 ± 0.969
1.795GlnArg: 1.795 ± 0.692
2.692GlnSer: 2.692 ± 1.5
2.243GlnThr: 2.243 ± 0.456
1.795GlnVal: 1.795 ± 0.694
0.449GlnTrp: 0.449 ± 0.633
0.897GlnTyr: 0.897 ± 0.629
0.0GlnXaa: 0.0 ± 0.0
Arg
2.692ArgAla: 2.692 ± 1.305
1.346ArgCys: 1.346 ± 0.528
2.692ArgAsp: 2.692 ± 0.723
4.935ArgGlu: 4.935 ± 1.208
3.589ArgPhe: 3.589 ± 0.978
1.795ArgGly: 1.795 ± 1.295
1.795ArgHis: 1.795 ± 0.791
2.243ArgIle: 2.243 ± 2.178
2.243ArgLys: 2.243 ± 1.03
3.589ArgLeu: 3.589 ± 2.034
0.897ArgMet: 0.897 ± 0.306
2.692ArgAsn: 2.692 ± 1.437
2.243ArgPro: 2.243 ± 0.846
1.795ArgGln: 1.795 ± 0.533
3.14ArgArg: 3.14 ± 0.855
5.384ArgSer: 5.384 ± 2.565
3.589ArgThr: 3.589 ± 1.582
3.589ArgVal: 3.589 ± 1.894
0.449ArgTrp: 0.449 ± 0.315
2.243ArgTyr: 2.243 ± 0.846
0.0ArgXaa: 0.0 ± 0.0
Ser
3.589SerAla: 3.589 ± 1.641
1.795SerCys: 1.795 ± 1.258
4.935SerAsp: 4.935 ± 1.859
7.178SerGlu: 7.178 ± 1.682
4.486SerPhe: 4.486 ± 0.737
5.832SerGly: 5.832 ± 0.688
2.243SerHis: 2.243 ± 0.456
4.038SerIle: 4.038 ± 0.911
5.384SerLys: 5.384 ± 2.111
7.178SerLeu: 7.178 ± 1.433
3.14SerMet: 3.14 ± 0.958
6.729SerAsn: 6.729 ± 2.98
1.795SerPro: 1.795 ± 1.122
1.795SerGln: 1.795 ± 1.122
4.486SerArg: 4.486 ± 1.006
10.319SerSer: 10.319 ± 1.48
8.524SerThr: 8.524 ± 1.793
7.627SerVal: 7.627 ± 0.999
0.449SerTrp: 0.449 ± 0.422
3.589SerTyr: 3.589 ± 0.978
0.0SerXaa: 0.0 ± 0.0
Thr
2.243ThrAla: 2.243 ± 1.045
0.449ThrCys: 0.449 ± 0.315
2.692ThrAsp: 2.692 ± 1.11
2.692ThrGlu: 2.692 ± 1.102
3.14ThrPhe: 3.14 ± 1.383
2.692ThrGly: 2.692 ± 1.305
1.795ThrHis: 1.795 ± 0.719
4.935ThrIle: 4.935 ± 2.464
3.589ThrLys: 3.589 ± 1.213
6.729ThrLeu: 6.729 ± 0.809
0.897ThrMet: 0.897 ± 0.629
3.589ThrAsn: 3.589 ± 2.034
2.243ThrPro: 2.243 ± 1.082
2.692ThrGln: 2.692 ± 1.457
2.243ThrArg: 2.243 ± 2.166
6.729ThrSer: 6.729 ± 1.662
4.038ThrThr: 4.038 ± 0.877
3.14ThrVal: 3.14 ± 1.805
0.897ThrTrp: 0.897 ± 0.36
1.795ThrTyr: 1.795 ± 1.122
0.0ThrXaa: 0.0 ± 0.0
Val
4.935ValAla: 4.935 ± 1.066
1.346ValCys: 1.346 ± 0.977
7.178ValAsp: 7.178 ± 3.545
8.524ValGlu: 8.524 ± 3.111
4.038ValPhe: 4.038 ± 1.259
3.589ValGly: 3.589 ± 0.757
1.346ValHis: 1.346 ± 0.944
2.692ValIle: 2.692 ± 0.362
4.038ValLys: 4.038 ± 2.358
8.075ValLeu: 8.075 ± 2.088
2.243ValMet: 2.243 ± 0.503
0.897ValAsn: 0.897 ± 0.36
3.589ValPro: 3.589 ± 1.705
0.897ValGln: 0.897 ± 0.619
3.589ValArg: 3.589 ± 2.104
4.935ValSer: 4.935 ± 1.014
2.243ValThr: 2.243 ± 0.832
8.075ValVal: 8.075 ± 2.235
0.897ValTrp: 0.897 ± 0.619
1.795ValTyr: 1.795 ± 0.426
0.0ValXaa: 0.0 ± 0.0
Trp
0.897TrpAla: 0.897 ± 0.629
0.0TrpCys: 0.0 ± 0.0
0.897TrpAsp: 0.897 ± 0.7
0.449TrpGlu: 0.449 ± 0.422
0.897TrpPhe: 0.897 ± 0.36
0.449TrpGly: 0.449 ± 0.633
0.449TrpHis: 0.449 ± 0.315
0.0TrpIle: 0.0 ± 0.0
1.346TrpLys: 1.346 ± 0.718
0.449TrpLeu: 0.449 ± 0.422
0.449TrpMet: 0.449 ± 0.422
0.0TrpAsn: 0.0 ± 0.0
0.449TrpPro: 0.449 ± 0.816
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.449TrpThr: 0.449 ± 0.315
1.795TrpVal: 1.795 ± 1.295
0.0TrpTrp: 0.0 ± 0.0
0.449TrpTyr: 0.449 ± 0.633
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.795TyrAla: 1.795 ± 0.791
1.346TyrCys: 1.346 ± 0.715
2.243TyrAsp: 2.243 ± 1.055
0.0TyrGlu: 0.0 ± 0.0
1.346TyrPhe: 1.346 ± 0.718
0.449TyrGly: 0.449 ± 0.315
0.897TyrHis: 0.897 ± 0.795
1.346TyrIle: 1.346 ± 1.01
0.897TyrLys: 0.897 ± 0.36
3.589TyrLeu: 3.589 ± 0.978
0.449TyrMet: 0.449 ± 0.315
2.692TyrAsn: 2.692 ± 1.055
0.0TyrPro: 0.0 ± 0.0
0.449TyrGln: 0.449 ± 0.633
0.897TyrArg: 0.897 ± 0.844
3.14TyrSer: 3.14 ± 0.503
0.897TyrThr: 0.897 ± 0.629
0.449TyrVal: 0.449 ± 0.633
0.0TyrTrp: 0.0 ± 0.0
1.346TyrTyr: 1.346 ± 0.718
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2230 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski