Amino acid dipepetide frequency for Gelidibacter gilvus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.254AlaAla: 4.254 ± 0.075	0.513AlaCys: 0.513 ± 0.02	3.498AlaAsp: 3.498 ± 0.056	3.994AlaGlu: 3.994 ± 0.072	3.409AlaPhe: 3.409 ± 0.056	3.944AlaGly: 3.944 ± 0.086	1.241AlaHis: 1.241 ± 0.037	5.622AlaIle: 5.622 ± 0.066	4.632AlaLys: 4.632 ± 0.069	6.392AlaLeu: 6.392 ± 0.075	1.652AlaMet: 1.652 ± 0.04	3.416AlaAsn: 3.416 ± 0.048	1.913AlaPro: 1.913 ± 0.046	2.532AlaGln: 2.532 ± 0.049	2.025AlaArg: 2.025 ± 0.044	4.325AlaSer: 4.325 ± 0.071	3.79AlaThr: 3.79 ± 0.063	4.054AlaVal: 4.054 ± 0.065	0.619AlaTrp: 0.619 ± 0.022	2.633AlaTyr: 2.633 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.421CysAla: 0.421 ± 0.019	0.095CysCys: 0.095 ± 0.01	0.408CysAsp: 0.408 ± 0.021	0.435CysGlu: 0.435 ± 0.019	0.377CysPhe: 0.377 ± 0.018	0.573CysGly: 0.573 ± 0.033	0.19CysHis: 0.19 ± 0.014	0.509CysIle: 0.509 ± 0.023	0.46CysLys: 0.46 ± 0.018	0.606CysLeu: 0.606 ± 0.021	0.155CysMet: 0.155 ± 0.012	0.337CysAsn: 0.337 ± 0.018	0.308CysPro: 0.308 ± 0.02	0.211CysGln: 0.211 ± 0.013	0.21CysArg: 0.21 ± 0.015	0.528CysSer: 0.528 ± 0.027	0.374CysThr: 0.374 ± 0.02	0.415CysVal: 0.415 ± 0.019	0.06CysTrp: 0.06 ± 0.006	0.281CysTyr: 0.281 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.19AspAla: 4.19 ± 0.067	0.386AspCys: 0.386 ± 0.02	3.259AspAsp: 3.259 ± 0.058	3.726AspGlu: 3.726 ± 0.064	3.626AspPhe: 3.626 ± 0.057	3.87AspGly: 3.87 ± 0.065	1.18AspHis: 1.18 ± 0.036	4.708AspIle: 4.708 ± 0.069	4.084AspLys: 4.084 ± 0.06	5.664AspLeu: 5.664 ± 0.069	1.253AspMet: 1.253 ± 0.03	3.024AspAsn: 3.024 ± 0.053	1.873AspPro: 1.873 ± 0.044	1.815AspGln: 1.815 ± 0.041	2.056AspArg: 2.056 ± 0.043	3.095AspSer: 3.095 ± 0.05	2.84AspThr: 2.84 ± 0.045	3.848AspVal: 3.848 ± 0.057	0.757AspTrp: 0.757 ± 0.026	2.955AspTyr: 2.955 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	4.422GluAla: 4.422 ± 0.07	0.327GluCys: 0.327 ± 0.02	3.753GluAsp: 3.753 ± 0.049	4.292GluGlu: 4.292 ± 0.077	3.125GluPhe: 3.125 ± 0.044	3.612GluGly: 3.612 ± 0.051	1.357GluHis: 1.357 ± 0.034	5.326GluIle: 5.326 ± 0.065	5.351GluLys: 5.351 ± 0.08	6.177GluLeu: 6.177 ± 0.086	1.652GluMet: 1.652 ± 0.036	4.486GluAsn: 4.486 ± 0.059	1.581GluPro: 1.581 ± 0.036	2.171GluGln: 2.171 ± 0.041	2.684GluArg: 2.684 ± 0.058	3.531GluSer: 3.531 ± 0.052	3.63GluThr: 3.63 ± 0.055	4.137GluVal: 4.137 ± 0.055	0.685GluTrp: 0.685 ± 0.024	2.116GluTyr: 2.116 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	2.92PheAla: 2.92 ± 0.051	0.369PheCys: 0.369 ± 0.016	3.366PheAsp: 3.366 ± 0.058	3.46PheGlu: 3.46 ± 0.054	2.657PhePhe: 2.657 ± 0.056	3.74PheGly: 3.74 ± 0.058	0.9PheHis: 0.9 ± 0.027	3.931PheIle: 3.931 ± 0.058	3.95PheLys: 3.95 ± 0.058	4.637PheLeu: 4.637 ± 0.074	1.164PheMet: 1.164 ± 0.031	3.213PheAsn: 3.213 ± 0.062	1.778PhePro: 1.778 ± 0.042	1.674PheGln: 1.674 ± 0.033	1.703PheArg: 1.703 ± 0.039	3.854PheSer: 3.854 ± 0.061	2.968PheThr: 2.968 ± 0.055	3.002PheVal: 3.002 ± 0.05	0.578PheTrp: 0.578 ± 0.021	2.177PheTyr: 2.177 ± 0.046	0.0PheXaa: 0.0 ± 0.0
Gly	4.083GlyAla: 4.083 ± 0.072	0.553GlyCys: 0.553 ± 0.029	3.374GlyAsp: 3.374 ± 0.056	3.405GlyGlu: 3.405 ± 0.052	3.621GlyPhe: 3.621 ± 0.056	4.455GlyGly: 4.455 ± 0.08	1.262GlyHis: 1.262 ± 0.032	5.263GlyIle: 5.263 ± 0.076	4.751GlyLys: 4.751 ± 0.073	5.695GlyLeu: 5.695 ± 0.083	1.695GlyMet: 1.695 ± 0.038	3.587GlyAsn: 3.587 ± 0.066	1.403GlyPro: 1.403 ± 0.043	1.997GlyGln: 1.997 ± 0.042	2.158GlyArg: 2.158 ± 0.041	4.135GlySer: 4.135 ± 0.065	3.929GlyThr: 3.929 ± 0.079	4.359GlyVal: 4.359 ± 0.067	0.719GlyTrp: 0.719 ± 0.025	2.833GlyTyr: 2.833 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.024HisAla: 1.024 ± 0.027	0.194HisCys: 0.194 ± 0.013	0.986HisAsp: 0.986 ± 0.026	1.035HisGlu: 1.035 ± 0.024	1.211HisPhe: 1.211 ± 0.033	1.135HisGly: 1.135 ± 0.029	0.526HisHis: 0.526 ± 0.022	1.591HisIle: 1.591 ± 0.036	1.321HisLys: 1.321 ± 0.029	2.11HisLeu: 2.11 ± 0.044	0.373HisMet: 0.373 ± 0.02	0.977HisAsn: 0.977 ± 0.029	1.025HisPro: 1.025 ± 0.028	0.844HisGln: 0.844 ± 0.029	0.735HisArg: 0.735 ± 0.026	1.168HisSer: 1.168 ± 0.03	1.035HisThr: 1.035 ± 0.027	1.048HisVal: 1.048 ± 0.025	0.233HisTrp: 0.233 ± 0.015	0.943HisTyr: 0.943 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.6IleAla: 5.6 ± 0.07	0.634IleCys: 0.634 ± 0.027	4.994IleAsp: 4.994 ± 0.065	5.368IleGlu: 5.368 ± 0.064	3.559IlePhe: 3.559 ± 0.056	5.21IleGly: 5.21 ± 0.078	1.419IleHis: 1.419 ± 0.035	6.027IleIle: 6.027 ± 0.092	5.797IleLys: 5.797 ± 0.067	7.084IleLeu: 7.084 ± 0.083	1.52IleMet: 1.52 ± 0.037	4.601IleAsn: 4.601 ± 0.066	3.32IlePro: 3.32 ± 0.057	2.546IleGln: 2.546 ± 0.051	2.589IleArg: 2.589 ± 0.048	5.694IleSer: 5.694 ± 0.07	4.742IleThr: 4.742 ± 0.075	4.789IleVal: 4.789 ± 0.066	0.711IleTrp: 0.711 ± 0.023	2.892IleTyr: 2.892 ± 0.054	0.0IleXaa: 0.0 ± 0.0
Lys	4.882LysAla: 4.882 ± 0.07	0.337LysCys: 0.337 ± 0.019	4.936LysAsp: 4.936 ± 0.063	5.619LysGlu: 5.619 ± 0.078	2.928LysPhe: 2.928 ± 0.051	4.256LysGly: 4.256 ± 0.061	1.477LysHis: 1.477 ± 0.035	5.76LysIle: 5.76 ± 0.065	5.914LysLys: 5.914 ± 0.084	6.388LysLeu: 6.388 ± 0.082	2.037LysMet: 2.037 ± 0.044	4.989LysAsn: 4.989 ± 0.068	2.428LysPro: 2.428 ± 0.042	2.68LysGln: 2.68 ± 0.053	2.948LysArg: 2.948 ± 0.049	4.794LysSer: 4.794 ± 0.063	4.851LysThr: 4.851 ± 0.053	4.552LysVal: 4.552 ± 0.062	0.754LysTrp: 0.754 ± 0.027	2.759LysTyr: 2.759 ± 0.046	0.0LysXaa: 0.0 ± 0.0
Leu	5.782LeuAla: 5.782 ± 0.074	0.659LeuCys: 0.659 ± 0.024	5.244LeuAsp: 5.244 ± 0.065	6.177LeuGlu: 6.177 ± 0.08	4.79LeuPhe: 4.79 ± 0.067	5.613LeuGly: 5.613 ± 0.079	1.672LeuHis: 1.672 ± 0.04	7.054LeuIle: 7.054 ± 0.097	8.015LeuLys: 8.015 ± 0.09	8.612LeuLeu: 8.612 ± 0.1	2.284LeuMet: 2.284 ± 0.045	5.706LeuAsn: 5.706 ± 0.064	3.545LeuPro: 3.545 ± 0.053	3.239LeuGln: 3.239 ± 0.054	3.368LeuArg: 3.368 ± 0.056	6.715LeuSer: 6.715 ± 0.078	5.212LeuThr: 5.212 ± 0.063	5.469LeuVal: 5.469 ± 0.072	0.87LeuTrp: 0.87 ± 0.025	3.262LeuTyr: 3.262 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	1.855MetAla: 1.855 ± 0.04	0.139MetCys: 0.139 ± 0.011	1.407MetAsp: 1.407 ± 0.031	1.536MetGlu: 1.536 ± 0.033	0.94MetPhe: 0.94 ± 0.026	1.458MetGly: 1.458 ± 0.035	0.438MetHis: 0.438 ± 0.018	1.652MetIle: 1.652 ± 0.04	2.076MetLys: 2.076 ± 0.043	1.995MetLeu: 1.995 ± 0.042	0.634MetMet: 0.634 ± 0.023	1.288MetAsn: 1.288 ± 0.035	0.95MetPro: 0.95 ± 0.028	0.841MetGln: 0.841 ± 0.026	0.935MetArg: 0.935 ± 0.026	1.543MetSer: 1.543 ± 0.036	1.384MetThr: 1.384 ± 0.036	1.502MetVal: 1.502 ± 0.039	0.179MetTrp: 0.179 ± 0.014	0.695MetTyr: 0.695 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	3.973AsnAla: 3.973 ± 0.063	0.4AsnCys: 0.4 ± 0.019	3.254AsnAsp: 3.254 ± 0.053	3.481AsnGlu: 3.481 ± 0.06	3.059AsnPhe: 3.059 ± 0.052	3.86AsnGly: 3.86 ± 0.074	1.177AsnHis: 1.177 ± 0.027	4.609AsnIle: 4.609 ± 0.058	3.957AsnLys: 3.957 ± 0.058	5.395AsnLeu: 5.395 ± 0.079	1.277AsnMet: 1.277 ± 0.031	3.495AsnAsn: 3.495 ± 0.066	2.69AsnPro: 2.69 ± 0.044	2.147AsnGln: 2.147 ± 0.045	2.222AsnArg: 2.222 ± 0.037	3.889AsnSer: 3.889 ± 0.06	3.545AsnThr: 3.545 ± 0.062	3.475AsnVal: 3.475 ± 0.052	0.731AsnTrp: 0.731 ± 0.023	2.846AsnTyr: 2.846 ± 0.057	0.0AsnXaa: 0.0 ± 0.0
Pro	1.885ProAla: 1.885 ± 0.041	0.193ProCys: 0.193 ± 0.016	2.078ProAsp: 2.078 ± 0.042	2.899ProGlu: 2.899 ± 0.047	1.912ProPhe: 1.912 ± 0.034	1.902ProGly: 1.902 ± 0.041	0.667ProHis: 0.667 ± 0.021	2.786ProIle: 2.786 ± 0.052	2.706ProLys: 2.706 ± 0.05	3.062ProLeu: 3.062 ± 0.057	0.809ProMet: 0.809 ± 0.03	2.295ProAsn: 2.295 ± 0.046	0.861ProPro: 0.861 ± 0.033	1.214ProGln: 1.214 ± 0.034	0.976ProArg: 0.976 ± 0.026	2.209ProSer: 2.209 ± 0.044	2.007ProThr: 2.007 ± 0.041	2.155ProVal: 2.155 ± 0.039	0.373ProTrp: 0.373 ± 0.016	1.481ProTyr: 1.481 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	2.055GlnAla: 2.055 ± 0.04	0.178GlnCys: 0.178 ± 0.013	1.81GlnAsp: 1.81 ± 0.042	2.225GlnGlu: 2.225 ± 0.045	1.723GlnPhe: 1.723 ± 0.04	1.907GlnGly: 1.907 ± 0.044	0.72GlnHis: 0.72 ± 0.027	2.717GlnIle: 2.717 ± 0.047	2.707GlnLys: 2.707 ± 0.052	3.649GlnLeu: 3.649 ± 0.057	0.918GlnMet: 0.918 ± 0.027	2.232GlnAsn: 2.232 ± 0.047	1.22GlnPro: 1.22 ± 0.029	1.426GlnGln: 1.426 ± 0.039	1.341GlnArg: 1.341 ± 0.037	2.112GlnSer: 2.112 ± 0.04	1.945GlnThr: 1.945 ± 0.043	1.986GlnVal: 1.986 ± 0.039	0.373GlnTrp: 0.373 ± 0.017	1.228GlnTyr: 1.228 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	2.219ArgAla: 2.219 ± 0.039	0.204ArgCys: 0.204 ± 0.014	1.907ArgAsp: 1.907 ± 0.039	2.209ArgGlu: 2.209 ± 0.049	1.966ArgPhe: 1.966 ± 0.034	1.991ArgGly: 1.991 ± 0.04	0.686ArgHis: 0.686 ± 0.023	2.875ArgIle: 2.875 ± 0.044	2.692ArgLys: 2.692 ± 0.05	3.458ArgLeu: 3.458 ± 0.053	0.958ArgMet: 0.958 ± 0.027	2.179ArgAsn: 2.179 ± 0.047	1.13ArgPro: 1.13 ± 0.031	1.229ArgGln: 1.229 ± 0.028	1.393ArgArg: 1.393 ± 0.033	2.093ArgSer: 2.093 ± 0.043	1.923ArgThr: 1.923 ± 0.041	2.126ArgVal: 2.126 ± 0.04	0.421ArgTrp: 0.421 ± 0.02	1.569ArgTyr: 1.569 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	3.925SerAla: 3.925 ± 0.062	0.602SerCys: 0.602 ± 0.022	3.75SerAsp: 3.75 ± 0.048	4.28SerGlu: 4.28 ± 0.066	3.671SerPhe: 3.671 ± 0.061	4.717SerGly: 4.717 ± 0.066	1.248SerHis: 1.248 ± 0.028	5.122SerIle: 5.122 ± 0.068	5.008SerLys: 5.008 ± 0.065	5.982SerLeu: 5.982 ± 0.069	1.338SerMet: 1.338 ± 0.034	3.723SerAsn: 3.723 ± 0.065	2.144SerPro: 2.144 ± 0.039	2.278SerGln: 2.278 ± 0.046	2.194SerArg: 2.194 ± 0.05	4.324SerSer: 4.324 ± 0.073	3.637SerThr: 3.637 ± 0.059	4.054SerVal: 4.054 ± 0.06	0.702SerTrp: 0.702 ± 0.025	2.819SerTyr: 2.819 ± 0.051	0.0SerXaa: 0.0 ± 0.0
Thr	3.706ThrAla: 3.706 ± 0.062	0.337ThrCys: 0.337 ± 0.017	3.443ThrAsp: 3.443 ± 0.055	3.457ThrGlu: 3.457 ± 0.056	3.053ThrPhe: 3.053 ± 0.062	3.868ThrGly: 3.868 ± 0.065	1.102ThrHis: 1.102 ± 0.031	5.057ThrIle: 5.057 ± 0.077	3.828ThrLys: 3.828 ± 0.057	5.551ThrLeu: 5.551 ± 0.072	1.106ThrMet: 1.106 ± 0.029	3.178ThrAsn: 3.178 ± 0.063	2.422ThrPro: 2.422 ± 0.047	1.871ThrGln: 1.871 ± 0.046	1.665ThrArg: 1.665 ± 0.037	3.872ThrSer: 3.872 ± 0.063	3.541ThrThr: 3.541 ± 0.074	3.819ThrVal: 3.819 ± 0.087	0.546ThrTrp: 0.546 ± 0.025	2.52ThrTyr: 2.52 ± 0.05	0.0ThrXaa: 0.0 ± 0.0
Val	4.16ValAla: 4.16 ± 0.057	0.451ValCys: 0.451 ± 0.02	3.63ValAsp: 3.63 ± 0.051	3.902ValGlu: 3.902 ± 0.048	3.433ValPhe: 3.433 ± 0.058	3.878ValGly: 3.878 ± 0.07	1.111ValHis: 1.111 ± 0.032	4.934ValIle: 4.934 ± 0.067	4.295ValLys: 4.295 ± 0.056	5.992ValLeu: 5.992 ± 0.071	1.487ValMet: 1.487 ± 0.038	3.463ValAsn: 3.463 ± 0.053	2.162ValPro: 2.162 ± 0.043	1.794ValGln: 1.794 ± 0.036	2.045ValArg: 2.045 ± 0.041	4.319ValSer: 4.319 ± 0.065	3.646ValThr: 3.646 ± 0.085	4.151ValVal: 4.151 ± 0.07	0.601ValTrp: 0.601 ± 0.027	2.359ValTyr: 2.359 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	0.57TrpAla: 0.57 ± 0.022	0.087TrpCys: 0.087 ± 0.009	0.648TrpAsp: 0.648 ± 0.023	0.654TrpGlu: 0.654 ± 0.022	0.554TrpPhe: 0.554 ± 0.02	0.592TrpGly: 0.592 ± 0.024	0.253TrpHis: 0.253 ± 0.013	0.765TrpIle: 0.765 ± 0.026	0.755TrpLys: 0.755 ± 0.025	1.02TrpLeu: 1.02 ± 0.031	0.323TrpMet: 0.323 ± 0.015	0.707TrpAsn: 0.707 ± 0.025	0.266TrpPro: 0.266 ± 0.014	0.41TrpGln: 0.41 ± 0.016	0.403TrpArg: 0.403 ± 0.018	0.71TrpSer: 0.71 ± 0.027	0.615TrpThr: 0.615 ± 0.026	0.631TrpVal: 0.631 ± 0.02	0.14TrpTrp: 0.14 ± 0.011	0.413TrpTyr: 0.413 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.533TyrAla: 2.533 ± 0.045	0.294TyrCys: 0.294 ± 0.015	2.463TyrAsp: 2.463 ± 0.047	2.262TyrGlu: 2.262 ± 0.043	2.426TyrPhe: 2.426 ± 0.049	2.698TyrGly: 2.698 ± 0.048	0.89TyrHis: 0.89 ± 0.025	2.788TyrIle: 2.788 ± 0.059	2.988TyrLys: 2.988 ± 0.053	3.818TyrLeu: 3.818 ± 0.059	0.811TyrMet: 0.811 ± 0.023	2.588TyrAsn: 2.588 ± 0.044	1.449TyrPro: 1.449 ± 0.032	1.552TyrGln: 1.552 ± 0.041	1.578TyrArg: 1.578 ± 0.037	2.608TyrSer: 2.608 ± 0.051	2.33TyrThr: 2.33 ± 0.047	2.24TyrVal: 2.24 ± 0.041	0.465TyrTrp: 0.465 ± 0.021	1.788TyrTyr: 1.788 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3732 proteins (1309719 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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