Amino acid dipepetide frequency for Salmon aquaparamyxovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.67AlaAla: 3.67 ± 0.817
0.551AlaCys: 0.551 ± 0.259
3.854AlaAsp: 3.854 ± 0.951
3.67AlaGlu: 3.67 ± 0.935
1.652AlaPhe: 1.652 ± 0.466
5.689AlaGly: 5.689 ± 0.848
0.184AlaHis: 0.184 ± 0.119
4.772AlaIle: 4.772 ± 1.785
3.303AlaLys: 3.303 ± 0.563
7.708AlaLeu: 7.708 ± 1.308
2.019AlaMet: 2.019 ± 0.451
2.936AlaAsn: 2.936 ± 0.628
2.386AlaPro: 2.386 ± 0.487
2.202AlaGln: 2.202 ± 0.288
2.202AlaArg: 2.202 ± 0.659
4.221AlaSer: 4.221 ± 1.119
4.404AlaThr: 4.404 ± 0.877
4.955AlaVal: 4.955 ± 1.161
0.184AlaTrp: 0.184 ± 0.228
2.386AlaTyr: 2.386 ± 0.707
0.0AlaXaa: 0.0 ± 0.0
Cys
0.184CysAla: 0.184 ± 0.193
0.918CysCys: 0.918 ± 0.303
0.918CysAsp: 0.918 ± 0.236
1.468CysGlu: 1.468 ± 0.598
0.367CysPhe: 0.367 ± 0.237
1.285CysGly: 1.285 ± 0.328
0.551CysHis: 0.551 ± 0.356
1.101CysIle: 1.101 ± 0.417
0.551CysLys: 0.551 ± 0.37
2.019CysLeu: 2.019 ± 0.51
0.184CysMet: 0.184 ± 0.119
0.551CysAsn: 0.551 ± 0.249
0.918CysPro: 0.918 ± 0.352
0.551CysGln: 0.551 ± 0.356
0.918CysArg: 0.918 ± 0.5
3.303CysSer: 3.303 ± 0.574
0.918CysThr: 0.918 ± 0.593
1.468CysVal: 1.468 ± 0.711
0.184CysTrp: 0.184 ± 0.187
1.101CysTyr: 1.101 ± 0.465
0.0CysXaa: 0.0 ± 0.0
Asp
1.835AspAla: 1.835 ± 0.698
0.734AspCys: 0.734 ± 0.266
5.322AspAsp: 5.322 ± 0.975
4.221AspGlu: 4.221 ± 0.707
0.918AspPhe: 0.918 ± 0.428
2.569AspGly: 2.569 ± 0.742
1.468AspHis: 1.468 ± 0.581
4.404AspIle: 4.404 ± 0.584
3.12AspLys: 3.12 ± 0.469
6.607AspLeu: 6.607 ± 1.263
2.753AspMet: 2.753 ± 0.88
2.019AspAsn: 2.019 ± 0.371
3.303AspPro: 3.303 ± 0.489
3.487AspGln: 3.487 ± 1.354
2.936AspArg: 2.936 ± 0.742
4.772AspSer: 4.772 ± 1.207
3.854AspThr: 3.854 ± 0.679
3.303AspVal: 3.303 ± 0.834
0.918AspTrp: 0.918 ± 0.43
2.569AspTyr: 2.569 ± 0.968
0.0AspXaa: 0.0 ± 0.0
Glu
3.303GluAla: 3.303 ± 0.704
0.551GluCys: 0.551 ± 0.242
3.67GluAsp: 3.67 ± 0.824
6.423GluGlu: 6.423 ± 1.857
1.652GluPhe: 1.652 ± 0.343
4.221GluGly: 4.221 ± 0.722
0.551GluHis: 0.551 ± 0.246
4.772GluIle: 4.772 ± 0.708
1.835GluLys: 1.835 ± 0.587
3.854GluLeu: 3.854 ± 0.363
1.285GluMet: 1.285 ± 0.399
2.202GluAsn: 2.202 ± 0.464
3.12GluPro: 3.12 ± 0.59
2.569GluGln: 2.569 ± 1.021
2.936GluArg: 2.936 ± 0.895
4.955GluSer: 4.955 ± 0.875
4.404GluThr: 4.404 ± 1.105
4.037GluVal: 4.037 ± 1.484
1.101GluTrp: 1.101 ± 0.55
1.468GluTyr: 1.468 ± 0.479
0.0GluXaa: 0.0 ± 0.0
Phe
1.652PheAla: 1.652 ± 0.574
0.918PheCys: 0.918 ± 0.436
0.551PheAsp: 0.551 ± 0.259
2.019PheGlu: 2.019 ± 0.947
1.285PhePhe: 1.285 ± 0.654
3.12PheGly: 3.12 ± 0.617
0.734PheHis: 0.734 ± 0.578
1.468PheIle: 1.468 ± 0.415
0.918PheLys: 0.918 ± 0.426
2.753PheLeu: 2.753 ± 1.038
1.652PheMet: 1.652 ± 0.894
2.202PheAsn: 2.202 ± 0.654
0.551PhePro: 0.551 ± 0.26
0.551PheGln: 0.551 ± 0.254
1.101PheArg: 1.101 ± 0.54
2.019PheSer: 2.019 ± 0.48
1.835PheThr: 1.835 ± 0.54
2.386PheVal: 2.386 ± 0.91
0.551PheTrp: 0.551 ± 0.259
0.918PheTyr: 0.918 ± 0.436
0.0PheXaa: 0.0 ± 0.0
Gly
5.506GlyAla: 5.506 ± 0.971
1.835GlyCys: 1.835 ± 0.75
4.772GlyAsp: 4.772 ± 0.564
4.037GlyGlu: 4.037 ± 0.838
1.835GlyPhe: 1.835 ± 0.664
5.139GlyGly: 5.139 ± 1.494
1.835GlyHis: 1.835 ± 0.49
4.037GlyIle: 4.037 ± 1.18
4.037GlyLys: 4.037 ± 1.446
6.607GlyLeu: 6.607 ± 0.902
1.101GlyMet: 1.101 ± 0.417
1.468GlyAsn: 1.468 ± 0.543
3.67GlyPro: 3.67 ± 0.801
1.835GlyGln: 1.835 ± 0.434
5.689GlyArg: 5.689 ± 0.756
2.569GlySer: 2.569 ± 0.404
4.037GlyThr: 4.037 ± 0.917
6.056GlyVal: 6.056 ± 1.332
0.551GlyTrp: 0.551 ± 0.333
3.487GlyTyr: 3.487 ± 0.379
0.0GlyXaa: 0.0 ± 0.0
His
1.101HisAla: 1.101 ± 0.271
0.551HisCys: 0.551 ± 0.333
1.285HisAsp: 1.285 ± 0.347
1.101HisGlu: 1.101 ± 0.563
0.184HisPhe: 0.184 ± 0.246
0.918HisGly: 0.918 ± 0.373
0.0HisHis: 0.0 ± 0.0
0.734HisIle: 0.734 ± 0.33
1.285HisLys: 1.285 ± 0.465
2.569HisLeu: 2.569 ± 0.61
0.367HisMet: 0.367 ± 0.237
1.101HisAsn: 1.101 ± 0.54
1.652HisPro: 1.652 ± 0.516
0.734HisGln: 0.734 ± 0.474
0.367HisArg: 0.367 ± 0.181
1.285HisSer: 1.285 ± 0.321
0.551HisThr: 0.551 ± 0.2
0.918HisVal: 0.918 ± 0.469
0.184HisTrp: 0.184 ± 0.119
0.367HisTyr: 0.367 ± 0.275
0.0HisXaa: 0.0 ± 0.0
Ile
4.404IleAla: 4.404 ± 1.143
1.285IleCys: 1.285 ± 0.433
4.221IleAsp: 4.221 ± 0.826
2.386IleGlu: 2.386 ± 0.58
2.019IlePhe: 2.019 ± 0.745
3.854IleGly: 3.854 ± 0.581
1.468IleHis: 1.468 ± 0.605
3.12IleIle: 3.12 ± 0.927
2.753IleLys: 2.753 ± 0.619
4.955IleLeu: 4.955 ± 0.95
1.285IleMet: 1.285 ± 0.344
2.936IleAsn: 2.936 ± 0.435
2.936IlePro: 2.936 ± 0.972
2.019IleGln: 2.019 ± 0.739
3.854IleArg: 3.854 ± 0.851
7.708IleSer: 7.708 ± 1.121
3.12IleThr: 3.12 ± 0.869
3.303IleVal: 3.303 ± 0.662
0.0IleTrp: 0.0 ± 0.0
2.569IleTyr: 2.569 ± 0.7
0.0IleXaa: 0.0 ± 0.0
Lys
2.936LysAla: 2.936 ± 0.452
0.734LysCys: 0.734 ± 0.329
3.67LysAsp: 3.67 ± 0.908
2.386LysGlu: 2.386 ± 0.699
1.468LysPhe: 1.468 ± 0.605
4.404LysGly: 4.404 ± 0.647
1.101LysHis: 1.101 ± 0.383
2.753LysIle: 2.753 ± 0.843
3.854LysLys: 3.854 ± 1.274
5.506LysLeu: 5.506 ± 0.796
1.468LysMet: 1.468 ± 0.557
1.652LysAsn: 1.652 ± 0.589
1.101LysPro: 1.101 ± 0.422
3.303LysGln: 3.303 ± 0.676
3.12LysArg: 3.12 ± 0.65
4.588LysSer: 4.588 ± 1.0
2.569LysThr: 2.569 ± 0.765
2.753LysVal: 2.753 ± 0.873
0.918LysTrp: 0.918 ± 0.41
1.101LysTyr: 1.101 ± 0.563
0.0LysXaa: 0.0 ± 0.0
Leu
5.139LeuAla: 5.139 ± 0.642
2.569LeuCys: 2.569 ± 0.675
6.79LeuAsp: 6.79 ± 0.965
5.139LeuGlu: 5.139 ± 1.893
2.386LeuPhe: 2.386 ± 0.455
6.423LeuGly: 6.423 ± 1.475
1.652LeuHis: 1.652 ± 0.438
5.689LeuIle: 5.689 ± 1.038
6.24LeuLys: 6.24 ± 1.819
8.075LeuLeu: 8.075 ± 1.861
2.936LeuMet: 2.936 ± 0.697
6.056LeuAsn: 6.056 ± 0.49
2.936LeuPro: 2.936 ± 0.661
3.67LeuGln: 3.67 ± 0.491
4.404LeuArg: 4.404 ± 0.548
6.79LeuSer: 6.79 ± 0.836
5.873LeuThr: 5.873 ± 1.008
5.506LeuVal: 5.506 ± 1.021
1.101LeuTrp: 1.101 ± 0.259
2.019LeuTyr: 2.019 ± 0.474
0.0LeuXaa: 0.0 ± 0.0
Met
2.202MetAla: 2.202 ± 0.474
0.551MetCys: 0.551 ± 0.259
0.734MetAsp: 0.734 ± 0.33
1.468MetGlu: 1.468 ± 0.434
0.367MetPhe: 0.367 ± 0.407
1.835MetGly: 1.835 ± 1.159
0.734MetHis: 0.734 ± 0.228
2.753MetIle: 2.753 ± 0.358
2.019MetLys: 2.019 ± 0.55
2.569MetLeu: 2.569 ± 0.911
0.367MetMet: 0.367 ± 0.196
2.019MetAsn: 2.019 ± 0.728
0.918MetPro: 0.918 ± 0.463
1.285MetGln: 1.285 ± 0.435
1.101MetArg: 1.101 ± 0.468
3.303MetSer: 3.303 ± 1.181
1.101MetThr: 1.101 ± 0.468
1.835MetVal: 1.835 ± 0.487
0.367MetTrp: 0.367 ± 0.206
0.367MetTyr: 0.367 ± 0.237
0.0MetXaa: 0.0 ± 0.0
Asn
2.569AsnAla: 2.569 ± 0.673
0.551AsnCys: 0.551 ± 0.356
1.835AsnAsp: 1.835 ± 0.389
2.202AsnGlu: 2.202 ± 0.74
0.918AsnPhe: 0.918 ± 0.449
3.487AsnGly: 3.487 ± 0.937
0.367AsnHis: 0.367 ± 0.237
2.753AsnIle: 2.753 ± 0.384
3.12AsnLys: 3.12 ± 1.104
4.221AsnLeu: 4.221 ± 0.532
1.285AsnMet: 1.285 ± 0.644
0.918AsnAsn: 0.918 ± 0.363
3.303AsnPro: 3.303 ± 0.394
2.202AsnGln: 2.202 ± 0.388
2.569AsnArg: 2.569 ± 0.739
3.67AsnSer: 3.67 ± 0.549
3.854AsnThr: 3.854 ± 1.031
2.386AsnVal: 2.386 ± 0.536
1.468AsnTrp: 1.468 ± 0.496
0.551AsnTyr: 0.551 ± 0.231
0.0AsnXaa: 0.0 ± 0.0
Pro
3.303ProAla: 3.303 ± 0.678
0.367ProCys: 0.367 ± 0.181
2.019ProAsp: 2.019 ± 0.518
3.67ProGlu: 3.67 ± 0.937
0.918ProPhe: 0.918 ± 0.448
3.854ProGly: 3.854 ± 1.631
0.551ProHis: 0.551 ± 0.242
2.753ProIle: 2.753 ± 0.879
2.569ProLys: 2.569 ± 0.961
3.12ProLeu: 3.12 ± 0.852
1.468ProMet: 1.468 ± 0.763
2.202ProAsn: 2.202 ± 0.377
2.753ProPro: 2.753 ± 1.35
1.652ProGln: 1.652 ± 0.475
3.67ProArg: 3.67 ± 0.76
3.854ProSer: 3.854 ± 0.55
3.67ProThr: 3.67 ± 0.821
3.854ProVal: 3.854 ± 0.83
0.551ProTrp: 0.551 ± 0.297
2.202ProTyr: 2.202 ± 0.519
0.0ProXaa: 0.0 ± 0.0
Gln
3.12GlnAla: 3.12 ± 0.829
0.734GlnCys: 0.734 ± 0.324
3.303GlnAsp: 3.303 ± 1.174
2.569GlnGlu: 2.569 ± 0.679
2.202GlnPhe: 2.202 ± 1.126
1.652GlnGly: 1.652 ± 0.496
0.367GlnHis: 0.367 ± 0.324
1.652GlnIle: 1.652 ± 0.455
3.12GlnLys: 3.12 ± 0.444
2.753GlnLeu: 2.753 ± 0.555
1.468GlnMet: 1.468 ± 0.535
1.835GlnAsn: 1.835 ± 0.618
1.468GlnPro: 1.468 ± 0.473
0.918GlnGln: 0.918 ± 0.302
1.652GlnArg: 1.652 ± 0.353
3.303GlnSer: 3.303 ± 1.05
1.835GlnThr: 1.835 ± 0.284
3.487GlnVal: 3.487 ± 0.739
0.734GlnTrp: 0.734 ± 0.329
1.101GlnTyr: 1.101 ± 0.592
0.0GlnXaa: 0.0 ± 0.0
Arg
2.386ArgAla: 2.386 ± 0.865
1.468ArgCys: 1.468 ± 0.603
4.221ArgAsp: 4.221 ± 0.956
3.303ArgGlu: 3.303 ± 0.857
1.101ArgPhe: 1.101 ± 0.422
4.221ArgGly: 4.221 ± 0.859
1.652ArgHis: 1.652 ± 0.511
2.936ArgIle: 2.936 ± 0.82
2.202ArgLys: 2.202 ± 0.377
3.854ArgLeu: 3.854 ± 1.135
1.285ArgMet: 1.285 ± 0.474
2.202ArgAsn: 2.202 ± 0.455
2.019ArgPro: 2.019 ± 0.3
1.835ArgGln: 1.835 ± 1.059
2.202ArgArg: 2.202 ± 0.516
5.139ArgSer: 5.139 ± 1.449
2.386ArgThr: 2.386 ± 0.394
5.506ArgVal: 5.506 ± 0.312
0.734ArgTrp: 0.734 ± 0.247
2.019ArgTyr: 2.019 ± 0.327
0.0ArgXaa: 0.0 ± 0.0
Ser
7.891SerAla: 7.891 ± 2.062
1.468SerCys: 1.468 ± 0.436
4.404SerAsp: 4.404 ± 1.074
4.221SerGlu: 4.221 ± 0.932
3.487SerPhe: 3.487 ± 0.675
5.322SerGly: 5.322 ± 0.493
0.734SerHis: 0.734 ± 0.328
5.322SerIle: 5.322 ± 1.295
3.12SerLys: 3.12 ± 1.02
8.075SerLeu: 8.075 ± 1.327
0.734SerMet: 0.734 ± 0.472
2.753SerAsn: 2.753 ± 0.45
6.056SerPro: 6.056 ± 2.317
4.037SerGln: 4.037 ± 0.935
3.67SerArg: 3.67 ± 0.72
8.625SerSer: 8.625 ± 3.146
7.341SerThr: 7.341 ± 0.728
5.873SerVal: 5.873 ± 1.03
0.918SerTrp: 0.918 ± 0.384
2.569SerTyr: 2.569 ± 0.541
0.0SerXaa: 0.0 ± 0.0
Thr
3.854ThrAla: 3.854 ± 0.727
0.734ThrCys: 0.734 ± 0.445
2.019ThrAsp: 2.019 ± 0.858
2.019ThrGlu: 2.019 ± 0.503
3.12ThrPhe: 3.12 ± 0.546
4.772ThrGly: 4.772 ± 0.984
1.101ThrHis: 1.101 ± 0.492
4.037ThrIle: 4.037 ± 0.659
3.12ThrLys: 3.12 ± 0.691
6.423ThrLeu: 6.423 ± 0.727
1.835ThrMet: 1.835 ± 0.548
2.202ThrAsn: 2.202 ± 0.649
3.487ThrPro: 3.487 ± 1.205
2.202ThrGln: 2.202 ± 0.371
4.955ThrArg: 4.955 ± 0.827
6.607ThrSer: 6.607 ± 1.239
3.67ThrThr: 3.67 ± 0.671
4.772ThrVal: 4.772 ± 0.708
0.734ThrTrp: 0.734 ± 0.276
1.468ThrTyr: 1.468 ± 0.411
0.0ThrXaa: 0.0 ± 0.0
Val
5.322ValAla: 5.322 ± 0.5
1.101ValCys: 1.101 ± 0.271
4.037ValAsp: 4.037 ± 0.641
5.139ValGlu: 5.139 ± 1.362
1.652ValPhe: 1.652 ± 0.496
4.772ValGly: 4.772 ± 1.159
1.285ValHis: 1.285 ± 0.324
2.386ValIle: 2.386 ± 0.759
1.835ValLys: 1.835 ± 0.515
6.423ValLeu: 6.423 ± 0.783
2.936ValMet: 2.936 ± 0.503
4.404ValAsn: 4.404 ± 0.708
3.12ValPro: 3.12 ± 0.687
2.202ValGln: 2.202 ± 0.457
4.221ValArg: 4.221 ± 0.45
6.056ValSer: 6.056 ± 1.434
4.772ValThr: 4.772 ± 0.776
6.423ValVal: 6.423 ± 1.272
0.184ValTrp: 0.184 ± 0.119
2.386ValTyr: 2.386 ± 0.627
0.0ValXaa: 0.0 ± 0.0
Trp
0.734TrpAla: 0.734 ± 0.313
0.367TrpCys: 0.367 ± 0.181
1.101TrpAsp: 1.101 ± 0.712
0.551TrpGlu: 0.551 ± 0.242
0.734TrpPhe: 0.734 ± 0.328
0.734TrpGly: 0.734 ± 0.247
0.184TrpHis: 0.184 ± 0.171
1.101TrpIle: 1.101 ± 0.361
0.734TrpLys: 0.734 ± 0.416
0.918TrpLeu: 0.918 ± 0.413
0.551TrpMet: 0.551 ± 0.356
0.734TrpAsn: 0.734 ± 0.413
0.184TrpPro: 0.184 ± 0.119
0.734TrpGln: 0.734 ± 0.251
0.367TrpArg: 0.367 ± 0.206
0.551TrpSer: 0.551 ± 0.259
0.551TrpThr: 0.551 ± 0.356
0.551TrpVal: 0.551 ± 0.375
0.0TrpTrp: 0.0 ± 0.0
0.918TrpTyr: 0.918 ± 0.448
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.835TyrAla: 1.835 ± 0.889
1.468TyrCys: 1.468 ± 0.482
2.386TyrAsp: 2.386 ± 0.366
0.918TyrGlu: 0.918 ± 0.302
0.918TyrPhe: 0.918 ± 0.454
1.835TyrGly: 1.835 ± 0.716
0.734TyrHis: 0.734 ± 0.474
1.652TyrIle: 1.652 ± 0.543
1.652TyrLys: 1.652 ± 0.399
2.569TyrLeu: 2.569 ± 0.58
0.734TyrMet: 0.734 ± 0.285
1.835TyrAsn: 1.835 ± 0.415
3.12TyrPro: 3.12 ± 0.562
1.285TyrGln: 1.285 ± 0.385
0.734TyrArg: 0.734 ± 0.233
3.303TyrSer: 3.303 ± 0.602
2.386TyrThr: 2.386 ± 0.463
1.285TyrVal: 1.285 ± 0.272
0.918TyrTrp: 0.918 ± 0.384
0.734TyrTyr: 0.734 ± 0.321
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (5450 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski