Amino acid dipepetide frequency for Aureimonas jatrophae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.632AlaAla: 18.632 ± 0.16	0.987AlaCys: 0.987 ± 0.03	7.578AlaAsp: 7.578 ± 0.081	8.379AlaGlu: 8.379 ± 0.085	4.614AlaPhe: 4.614 ± 0.061	11.574AlaGly: 11.574 ± 0.103	2.185AlaHis: 2.185 ± 0.049	6.354AlaIle: 6.354 ± 0.068	3.149AlaLys: 3.149 ± 0.053	14.857AlaLeu: 14.857 ± 0.129	3.663AlaMet: 3.663 ± 0.056	2.692AlaAsn: 2.692 ± 0.051	6.275AlaPro: 6.275 ± 0.099	3.78AlaGln: 3.78 ± 0.063	10.245AlaArg: 10.245 ± 0.098	7.294AlaSer: 7.294 ± 0.081	6.387AlaThr: 6.387 ± 0.078	9.945AlaVal: 9.945 ± 0.096	1.383AlaTrp: 1.383 ± 0.035	2.249AlaTyr: 2.249 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.872CysAla: 0.872 ± 0.028	0.088CysCys: 0.088 ± 0.008	0.47CysAsp: 0.47 ± 0.018	0.43CysGlu: 0.43 ± 0.018	0.291CysPhe: 0.291 ± 0.016	0.836CysGly: 0.836 ± 0.029	0.199CysHis: 0.199 ± 0.013	0.293CysIle: 0.293 ± 0.015	0.105CysLys: 0.105 ± 0.008	0.789CysLeu: 0.789 ± 0.025	0.113CysMet: 0.113 ± 0.009	0.153CysAsn: 0.153 ± 0.01	0.361CysPro: 0.361 ± 0.017	0.177CysGln: 0.177 ± 0.011	0.669CysArg: 0.669 ± 0.026	0.342CysSer: 0.342 ± 0.016	0.336CysThr: 0.336 ± 0.016	0.585CysVal: 0.585 ± 0.022	0.104CysTrp: 0.104 ± 0.01	0.131CysTyr: 0.131 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.745AspAla: 7.745 ± 0.084	0.422AspCys: 0.422 ± 0.017	3.157AspAsp: 3.157 ± 0.059	3.949AspGlu: 3.949 ± 0.057	1.939AspPhe: 1.939 ± 0.039	5.708AspGly: 5.708 ± 0.067	1.19AspHis: 1.19 ± 0.033	2.536AspIle: 2.536 ± 0.045	1.186AspLys: 1.186 ± 0.034	6.37AspLeu: 6.37 ± 0.082	1.191AspMet: 1.191 ± 0.03	1.062AspAsn: 1.062 ± 0.031	3.895AspPro: 3.895 ± 0.048	1.483AspGln: 1.483 ± 0.03	5.158AspArg: 5.158 ± 0.077	1.665AspSer: 1.665 ± 0.037	2.734AspThr: 2.734 ± 0.043	4.325AspVal: 4.325 ± 0.067	0.944AspTrp: 0.944 ± 0.022	1.322AspTyr: 1.322 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	9.052GluAla: 9.052 ± 0.101	0.304GluCys: 0.304 ± 0.015	2.836GluAsp: 2.836 ± 0.044	3.111GluGlu: 3.111 ± 0.058	1.647GluPhe: 1.647 ± 0.034	4.895GluGly: 4.895 ± 0.073	1.123GluHis: 1.123 ± 0.028	3.379GluIle: 3.379 ± 0.054	1.512GluLys: 1.512 ± 0.042	5.192GluLeu: 5.192 ± 0.078	1.372GluMet: 1.372 ± 0.031	1.402GluAsn: 1.402 ± 0.035	3.355GluPro: 3.355 ± 0.052	1.553GluGln: 1.553 ± 0.035	6.692GluArg: 6.692 ± 0.075	2.146GluSer: 2.146 ± 0.041	4.029GluThr: 4.029 ± 0.05	3.914GluVal: 3.914 ± 0.05	0.637GluTrp: 0.637 ± 0.021	0.762GluTyr: 0.762 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.827PheAla: 4.827 ± 0.063	0.35PheCys: 0.35 ± 0.017	2.595PheAsp: 2.595 ± 0.044	2.278PheGlu: 2.278 ± 0.039	1.317PhePhe: 1.317 ± 0.037	3.766PheGly: 3.766 ± 0.058	0.74PheHis: 0.74 ± 0.026	1.266PheIle: 1.266 ± 0.034	0.682PheLys: 0.682 ± 0.021	3.669PheLeu: 3.669 ± 0.06	0.676PheMet: 0.676 ± 0.024	0.826PheAsn: 0.826 ± 0.023	1.559PhePro: 1.559 ± 0.035	1.041PheGln: 1.041 ± 0.029	2.762PheArg: 2.762 ± 0.044	1.955PheSer: 1.955 ± 0.039	1.779PheThr: 1.779 ± 0.035	3.119PheVal: 3.119 ± 0.047	0.5PheTrp: 0.5 ± 0.022	0.796PheTyr: 0.796 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	10.499GlyAla: 10.499 ± 0.096	0.764GlyCys: 0.764 ± 0.026	4.816GlyAsp: 4.816 ± 0.077	5.665GlyGlu: 5.665 ± 0.079	3.744GlyPhe: 3.744 ± 0.057	7.775GlyGly: 7.775 ± 0.113	1.854GlyHis: 1.854 ± 0.041	4.33GlyIle: 4.33 ± 0.062	2.15GlyLys: 2.15 ± 0.049	9.24GlyLeu: 9.24 ± 0.095	1.944GlyMet: 1.944 ± 0.039	1.924GlyAsn: 1.924 ± 0.049	3.703GlyPro: 3.703 ± 0.059	2.726GlyGln: 2.726 ± 0.052	7.762GlyArg: 7.762 ± 0.085	5.091GlySer: 5.091 ± 0.076	5.168GlyThr: 5.168 ± 0.066	6.367GlyVal: 6.367 ± 0.083	1.364GlyTrp: 1.364 ± 0.035	2.131GlyTyr: 2.131 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.404HisAla: 2.404 ± 0.051	0.18HisCys: 0.18 ± 0.011	1.204HisAsp: 1.204 ± 0.033	1.082HisGlu: 1.082 ± 0.034	0.733HisPhe: 0.733 ± 0.028	1.855HisGly: 1.855 ± 0.037	0.525HisHis: 0.525 ± 0.024	0.676HisIle: 0.676 ± 0.025	0.348HisLys: 0.348 ± 0.017	2.041HisLeu: 2.041 ± 0.038	0.434HisMet: 0.434 ± 0.019	0.342HisAsn: 0.342 ± 0.015	1.374HisPro: 1.374 ± 0.037	0.499HisGln: 0.499 ± 0.021	1.504HisArg: 1.504 ± 0.031	0.802HisSer: 0.802 ± 0.025	0.709HisThr: 0.709 ± 0.023	1.569HisVal: 1.569 ± 0.032	0.269HisTrp: 0.269 ± 0.014	0.461HisTyr: 0.461 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.679IleAla: 6.679 ± 0.08	0.38IleCys: 0.38 ± 0.018	3.211IleAsp: 3.211 ± 0.049	3.355IleGlu: 3.355 ± 0.043	1.352IlePhe: 1.352 ± 0.036	4.69IleGly: 4.69 ± 0.07	0.834IleHis: 0.834 ± 0.027	1.387IleIle: 1.387 ± 0.041	0.841IleLys: 0.841 ± 0.027	4.548IleLeu: 4.548 ± 0.066	0.751IleMet: 0.751 ± 0.026	1.021IleAsn: 1.021 ± 0.031	2.036IlePro: 2.036 ± 0.04	1.153IleGln: 1.153 ± 0.032	3.395IleArg: 3.395 ± 0.056	2.146IleSer: 2.146 ± 0.043	2.069IleThr: 2.069 ± 0.04	4.079IleVal: 4.079 ± 0.052	0.517IleTrp: 0.517 ± 0.02	0.863IleTyr: 0.863 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	2.967LysAla: 2.967 ± 0.056	0.093LysCys: 0.093 ± 0.009	1.165LysAsp: 1.165 ± 0.032	0.976LysGlu: 0.976 ± 0.027	0.522LysPhe: 0.522 ± 0.017	2.099LysGly: 2.099 ± 0.044	0.372LysHis: 0.372 ± 0.02	1.017LysIle: 1.017 ± 0.029	0.621LysLys: 0.621 ± 0.025	2.375LysLeu: 2.375 ± 0.046	0.504LysMet: 0.504 ± 0.02	0.526LysAsn: 0.526 ± 0.024	1.606LysPro: 1.606 ± 0.038	0.569LysGln: 0.569 ± 0.023	1.981LysArg: 1.981 ± 0.042	1.271LysSer: 1.271 ± 0.033	1.387LysThr: 1.387 ± 0.036	1.685LysVal: 1.685 ± 0.044	0.204LysTrp: 0.204 ± 0.012	0.373LysTyr: 0.373 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	15.362LeuAla: 15.362 ± 0.13	0.898LeuCys: 0.898 ± 0.025	6.443LeuAsp: 6.443 ± 0.078	5.322LeuGlu: 5.322 ± 0.06	3.794LeuPhe: 3.794 ± 0.064	9.004LeuGly: 9.004 ± 0.09	1.838LeuHis: 1.838 ± 0.041	3.912LeuIle: 3.912 ± 0.061	2.475LeuLys: 2.475 ± 0.054	10.291LeuLeu: 10.291 ± 0.116	2.029LeuMet: 2.029 ± 0.04	2.245LeuAsn: 2.245 ± 0.043	5.882LeuPro: 5.882 ± 0.07	2.928LeuGln: 2.928 ± 0.044	8.533LeuArg: 8.533 ± 0.089	6.582LeuSer: 6.582 ± 0.084	5.31LeuThr: 5.31 ± 0.068	8.845LeuVal: 8.845 ± 0.103	1.132LeuTrp: 1.132 ± 0.03	1.894LeuTyr: 1.894 ± 0.042	0.001LeuXaa: 0.001 ± 0.001
Met	2.865MetAla: 2.865 ± 0.048	0.088MetCys: 0.088 ± 0.008	1.063MetAsp: 1.063 ± 0.026	0.994MetGlu: 0.994 ± 0.026	0.508MetPhe: 0.508 ± 0.021	1.747MetGly: 1.747 ± 0.044	0.344MetHis: 0.344 ± 0.016	1.152MetIle: 1.152 ± 0.031	0.648MetLys: 0.648 ± 0.025	2.175MetLeu: 2.175 ± 0.043	0.558MetMet: 0.558 ± 0.022	0.677MetAsn: 0.677 ± 0.026	1.419MetPro: 1.419 ± 0.036	0.626MetGln: 0.626 ± 0.024	2.096MetArg: 2.096 ± 0.043	1.601MetSer: 1.601 ± 0.035	1.79MetThr: 1.79 ± 0.039	1.582MetVal: 1.582 ± 0.04	0.147MetTrp: 0.147 ± 0.01	0.223MetTyr: 0.223 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.842AsnAla: 2.842 ± 0.056	0.178AsnCys: 0.178 ± 0.01	1.239AsnAsp: 1.239 ± 0.035	1.233AsnGlu: 1.233 ± 0.033	0.778AsnPhe: 0.778 ± 0.024	2.292AsnGly: 2.292 ± 0.05	0.415AsnHis: 0.415 ± 0.018	0.977AsnIle: 0.977 ± 0.029	0.49AsnLys: 0.49 ± 0.021	2.226AsnLeu: 2.226 ± 0.043	0.487AsnMet: 0.487 ± 0.02	0.544AsnAsn: 0.544 ± 0.022	1.479AsnPro: 1.479 ± 0.034	0.661AsnGln: 0.661 ± 0.02	1.785AsnArg: 1.785 ± 0.039	0.934AsnSer: 0.934 ± 0.024	1.09AsnThr: 1.09 ± 0.029	1.771AsnVal: 1.771 ± 0.038	0.352AsnTrp: 0.352 ± 0.018	0.539AsnTyr: 0.539 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	7.286ProAla: 7.286 ± 0.095	0.273ProCys: 0.273 ± 0.014	3.903ProAsp: 3.903 ± 0.058	3.622ProGlu: 3.622 ± 0.06	2.163ProPhe: 2.163 ± 0.034	4.84ProGly: 4.84 ± 0.075	1.051ProHis: 1.051 ± 0.028	2.34ProIle: 2.34 ± 0.041	1.241ProLys: 1.241 ± 0.03	5.051ProLeu: 5.051 ± 0.063	1.165ProMet: 1.165 ± 0.031	1.263ProAsn: 1.263 ± 0.031	2.7ProPro: 2.7 ± 0.063	1.409ProGln: 1.409 ± 0.034	3.51ProArg: 3.51 ± 0.059	2.998ProSer: 2.998 ± 0.052	2.767ProThr: 2.767 ± 0.053	4.549ProVal: 4.549 ± 0.059	0.64ProTrp: 0.64 ± 0.021	1.131ProTyr: 1.131 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.041GlnAla: 4.041 ± 0.059	0.146GlnCys: 0.146 ± 0.012	1.37GlnAsp: 1.37 ± 0.031	1.268GlnGlu: 1.268 ± 0.029	0.905GlnPhe: 0.905 ± 0.025	2.249GlnGly: 2.249 ± 0.039	0.494GlnHis: 0.494 ± 0.018	1.609GlnIle: 1.609 ± 0.037	0.697GlnLys: 0.697 ± 0.023	2.636GlnLeu: 2.636 ± 0.046	0.715GlnMet: 0.715 ± 0.025	0.754GlnAsn: 0.754 ± 0.025	1.772GlnPro: 1.772 ± 0.04	0.92GlnGln: 0.92 ± 0.038	2.535GlnArg: 2.535 ± 0.044	1.673GlnSer: 1.673 ± 0.032	1.747GlnThr: 1.747 ± 0.037	2.051GlnVal: 2.051 ± 0.039	0.297GlnTrp: 0.297 ± 0.013	0.466GlnTyr: 0.466 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	9.391ArgAla: 9.391 ± 0.105	0.546ArgCys: 0.546 ± 0.022	4.811ArgAsp: 4.811 ± 0.07	5.356ArgGlu: 5.356 ± 0.069	3.817ArgPhe: 3.817 ± 0.054	5.686ArgGly: 5.686 ± 0.072	1.919ArgHis: 1.919 ± 0.041	4.461ArgIle: 4.461 ± 0.057	1.621ArgLys: 1.621 ± 0.038	9.728ArgLeu: 9.728 ± 0.101	2.049ArgMet: 2.049 ± 0.039	1.844ArgAsn: 1.844 ± 0.042	4.407ArgPro: 4.407 ± 0.064	2.768ArgGln: 2.768 ± 0.047	7.953ArgArg: 7.953 ± 0.092	4.591ArgSer: 4.591 ± 0.068	4.181ArgThr: 4.181 ± 0.059	5.661ArgVal: 5.661 ± 0.075	1.203ArgTrp: 1.203 ± 0.035	1.777ArgTyr: 1.777 ± 0.035	0.001ArgXaa: 0.001 ± 0.001
Ser	6.419SerAla: 6.419 ± 0.082	0.377SerCys: 0.377 ± 0.018	2.917SerAsp: 2.917 ± 0.052	2.712SerGlu: 2.712 ± 0.044	2.293SerPhe: 2.293 ± 0.041	5.636SerGly: 5.636 ± 0.076	0.982SerHis: 0.982 ± 0.029	2.469SerIle: 2.469 ± 0.047	1.084SerLys: 1.084 ± 0.029	5.586SerLeu: 5.586 ± 0.063	1.165SerMet: 1.165 ± 0.03	1.214SerAsn: 1.214 ± 0.032	2.904SerPro: 2.904 ± 0.047	1.548SerGln: 1.548 ± 0.037	4.114SerArg: 4.114 ± 0.062	2.852SerSer: 2.852 ± 0.054	2.595SerThr: 2.595 ± 0.046	4.23SerVal: 4.23 ± 0.062	0.751SerTrp: 0.751 ± 0.022	1.18SerTyr: 1.18 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	6.339ThrAla: 6.339 ± 0.081	0.341ThrCys: 0.341 ± 0.02	2.879ThrAsp: 2.879 ± 0.05	2.59ThrGlu: 2.59 ± 0.044	1.936ThrPhe: 1.936 ± 0.035	5.187ThrGly: 5.187 ± 0.068	0.975ThrHis: 0.975 ± 0.028	2.713ThrIle: 2.713 ± 0.05	1.174ThrLys: 1.174 ± 0.031	6.265ThrLeu: 6.265 ± 0.074	1.114ThrMet: 1.114 ± 0.027	1.163ThrAsn: 1.163 ± 0.03	3.2ThrPro: 3.2 ± 0.06	1.517ThrGln: 1.517 ± 0.037	3.84ThrArg: 3.84 ± 0.055	2.66ThrSer: 2.66 ± 0.046	2.849ThrThr: 2.849 ± 0.05	4.663ThrVal: 4.663 ± 0.068	0.555ThrTrp: 0.555 ± 0.022	1.109ThrTyr: 1.109 ± 0.029	0.001ThrXaa: 0.001 ± 0.001
Val	10.473ValAla: 10.473 ± 0.109	0.627ValCys: 0.627 ± 0.023	4.45ValAsp: 4.45 ± 0.056	4.982ValGlu: 4.982 ± 0.059	2.929ValPhe: 2.929 ± 0.05	6.295ValGly: 6.295 ± 0.078	1.29ValHis: 1.29 ± 0.03	3.214ValIle: 3.214 ± 0.06	1.58ValLys: 1.58 ± 0.039	8.122ValLeu: 8.122 ± 0.093	1.678ValMet: 1.678 ± 0.041	1.793ValAsn: 1.793 ± 0.044	4.265ValPro: 4.265 ± 0.058	1.909ValGln: 1.909 ± 0.04	6.065ValArg: 6.065 ± 0.07	4.7ValSer: 4.7 ± 0.073	4.409ValThr: 4.409 ± 0.063	6.86ValVal: 6.86 ± 0.089	0.911ValTrp: 0.911 ± 0.029	1.4ValTyr: 1.4 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.113TrpAla: 1.113 ± 0.031	0.13TrpCys: 0.13 ± 0.01	0.598TrpAsp: 0.598 ± 0.023	0.509TrpGlu: 0.509 ± 0.022	0.501TrpPhe: 0.501 ± 0.021	0.874TrpGly: 0.874 ± 0.026	0.294TrpHis: 0.294 ± 0.013	0.626TrpIle: 0.626 ± 0.024	0.273TrpLys: 0.273 ± 0.014	1.488TrpLeu: 1.488 ± 0.035	0.348TrpMet: 0.348 ± 0.016	0.387TrpAsn: 0.387 ± 0.018	0.676TrpPro: 0.676 ± 0.024	0.468TrpGln: 0.468 ± 0.021	1.342TrpArg: 1.342 ± 0.033	0.821TrpSer: 0.821 ± 0.023	0.827TrpThr: 0.827 ± 0.023	0.717TrpVal: 0.717 ± 0.028	0.239TrpTrp: 0.239 ± 0.012	0.226TrpTyr: 0.226 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.413TyrAla: 2.413 ± 0.039	0.175TyrCys: 0.175 ± 0.012	1.277TyrAsp: 1.277 ± 0.035	1.1TyrGlu: 1.1 ± 0.029	0.723TyrPhe: 0.723 ± 0.026	2.013TyrGly: 2.013 ± 0.044	0.387TyrHis: 0.387 ± 0.016	0.595TyrIle: 0.595 ± 0.023	0.435TyrLys: 0.435 ± 0.019	2.071TyrLeu: 2.071 ± 0.039	0.345TyrMet: 0.345 ± 0.015	0.48TyrAsn: 0.48 ± 0.021	1.034TyrPro: 1.034 ± 0.029	0.609TyrGln: 0.609 ± 0.023	1.83TyrArg: 1.83 ± 0.043	0.903TyrSer: 0.903 ± 0.026	0.907TyrThr: 0.907 ± 0.027	1.433TyrVal: 1.433 ± 0.031	0.307TyrTrp: 0.307 ± 0.014	0.487TyrTyr: 0.487 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.005XaaXaa: 0.005 ± 0.003

Statistics based on 4295 proteins (1370096 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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