Amino acid dipepetide frequency for [Pantoea] beijingensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.794AlaAla: 9.794 ± 0.122	1.027AlaCys: 1.027 ± 0.028	5.115AlaAsp: 5.115 ± 0.154	5.72AlaGlu: 5.72 ± 0.089	3.618AlaPhe: 3.618 ± 0.066	7.541AlaGly: 7.541 ± 0.095	1.827AlaHis: 1.827 ± 0.047	6.163AlaIle: 6.163 ± 0.086	3.635AlaLys: 3.635 ± 0.065	11.912AlaLeu: 11.912 ± 0.138	2.998AlaMet: 2.998 ± 0.05	3.179AlaAsn: 3.179 ± 0.055	3.368AlaPro: 3.368 ± 0.057	4.292AlaGln: 4.292 ± 0.075	5.554AlaArg: 5.554 ± 0.08	5.699AlaSer: 5.699 ± 0.081	4.687AlaThr: 4.687 ± 0.065	6.435AlaVal: 6.435 ± 0.076	1.456AlaTrp: 1.456 ± 0.034	1.991AlaTyr: 1.991 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	0.853CysAla: 0.853 ± 0.025	0.187CysCys: 0.187 ± 0.013	0.546CysAsp: 0.546 ± 0.021	0.52CysGlu: 0.52 ± 0.021	0.47CysPhe: 0.47 ± 0.019	1.076CysGly: 1.076 ± 0.032	0.322CysHis: 0.322 ± 0.017	0.571CysIle: 0.571 ± 0.023	0.308CysLys: 0.308 ± 0.015	1.005CysLeu: 1.005 ± 0.032	0.233CysMet: 0.233 ± 0.013	0.316CysAsn: 0.316 ± 0.018	0.455CysPro: 0.455 ± 0.023	0.453CysGln: 0.453 ± 0.017	0.584CysArg: 0.584 ± 0.026	0.653CysSer: 0.653 ± 0.025	0.453CysThr: 0.453 ± 0.022	0.705CysVal: 0.705 ± 0.026	0.187CysTrp: 0.187 ± 0.013	0.341CysTyr: 0.341 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	5.405AspAla: 5.405 ± 0.151	0.493AspCys: 0.493 ± 0.022	2.993AspAsp: 2.993 ± 0.06	3.514AspGlu: 3.514 ± 0.062	2.269AspPhe: 2.269 ± 0.05	3.646AspGly: 3.646 ± 0.062	1.006AspHis: 1.006 ± 0.028	3.649AspIle: 3.649 ± 0.063	2.465AspLys: 2.465 ± 0.052	4.605AspLeu: 4.605 ± 0.069	1.328AspMet: 1.328 ± 0.038	2.237AspAsn: 2.237 ± 0.054	2.174AspPro: 2.174 ± 0.045	1.489AspGln: 1.489 ± 0.038	3.012AspArg: 3.012 ± 0.059	3.168AspSer: 3.168 ± 0.134	2.524AspThr: 2.524 ± 0.05	3.857AspVal: 3.857 ± 0.06	0.796AspTrp: 0.796 ± 0.023	1.862AspTyr: 1.862 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	5.286GluAla: 5.286 ± 0.086	0.433GluCys: 0.433 ± 0.019	2.304GluAsp: 2.304 ± 0.051	3.318GluGlu: 3.318 ± 0.066	1.745GluPhe: 1.745 ± 0.042	3.518GluGly: 3.518 ± 0.059	1.431GluHis: 1.431 ± 0.036	3.329GluIle: 3.329 ± 0.056	3.171GluLys: 3.171 ± 0.062	5.751GluLeu: 5.751 ± 0.068	1.774GluMet: 1.774 ± 0.046	2.444GluAsn: 2.444 ± 0.052	1.998GluPro: 1.998 ± 0.04	3.367GluGln: 3.367 ± 0.062	3.706GluArg: 3.706 ± 0.061	3.093GluSer: 3.093 ± 0.048	2.868GluThr: 2.868 ± 0.061	3.611GluVal: 3.611 ± 0.069	0.767GluTrp: 0.767 ± 0.029	1.354GluTyr: 1.354 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.535PheAla: 3.535 ± 0.067	0.508PheCys: 0.508 ± 0.022	2.318PheAsp: 2.318 ± 0.048	1.784PheGlu: 1.784 ± 0.044	1.683PhePhe: 1.683 ± 0.047	3.209PheGly: 3.209 ± 0.064	0.844PheHis: 0.844 ± 0.029	2.684PheIle: 2.684 ± 0.059	1.259PheLys: 1.259 ± 0.034	3.473PheLeu: 3.473 ± 0.075	1.017PheMet: 1.017 ± 0.036	1.764PheAsn: 1.764 ± 0.039	1.573PhePro: 1.573 ± 0.037	1.2PheGln: 1.2 ± 0.033	1.883PheArg: 1.883 ± 0.036	3.29PheSer: 3.29 ± 0.064	2.404PheThr: 2.404 ± 0.05	2.329PheVal: 2.329 ± 0.05	0.626PheTrp: 0.626 ± 0.023	1.256PheTyr: 1.256 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	6.164GlyAla: 6.164 ± 0.087	0.998GlyCys: 0.998 ± 0.035	3.611GlyAsp: 3.611 ± 0.067	4.522GlyGlu: 4.522 ± 0.067	3.272GlyPhe: 3.272 ± 0.06	5.285GlyGly: 5.285 ± 0.091	1.692GlyHis: 1.692 ± 0.041	5.21GlyIle: 5.21 ± 0.078	3.945GlyLys: 3.945 ± 0.064	7.491GlyLeu: 7.491 ± 0.104	2.348GlyMet: 2.348 ± 0.046	2.816GlyAsn: 2.816 ± 0.054	2.031GlyPro: 2.031 ± 0.046	2.932GlyGln: 2.932 ± 0.055	3.878GlyArg: 3.878 ± 0.07	4.36GlySer: 4.36 ± 0.066	3.803GlyThr: 3.803 ± 0.064	5.528GlyVal: 5.528 ± 0.072	1.293GlyTrp: 1.293 ± 0.03	2.57GlyTyr: 2.57 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.017HisAla: 2.017 ± 0.042	0.318HisCys: 0.318 ± 0.016	1.226HisAsp: 1.226 ± 0.038	1.147HisGlu: 1.147 ± 0.031	1.115HisPhe: 1.115 ± 0.032	1.702HisGly: 1.702 ± 0.039	0.791HisHis: 0.791 ± 0.029	1.39HisIle: 1.39 ± 0.036	0.756HisLys: 0.756 ± 0.028	2.424HisLeu: 2.424 ± 0.043	0.558HisMet: 0.558 ± 0.023	0.883HisAsn: 0.883 ± 0.031	1.376HisPro: 1.376 ± 0.04	1.35HisGln: 1.35 ± 0.043	1.33HisArg: 1.33 ± 0.04	1.302HisSer: 1.302 ± 0.033	1.049HisThr: 1.049 ± 0.03	1.312HisVal: 1.312 ± 0.037	0.447HisTrp: 0.447 ± 0.023	0.928HisTyr: 0.928 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.706IleAla: 6.706 ± 0.08	0.678IleCys: 0.678 ± 0.024	3.805IleAsp: 3.805 ± 0.07	3.544IleGlu: 3.544 ± 0.062	2.162IlePhe: 2.162 ± 0.055	4.866IleGly: 4.866 ± 0.074	1.256IleHis: 1.256 ± 0.034	3.591IleIle: 3.591 ± 0.076	2.456IleLys: 2.456 ± 0.053	5.263IleLeu: 5.263 ± 0.079	1.402IleMet: 1.402 ± 0.035	2.757IleAsn: 2.757 ± 0.054	2.717IlePro: 2.717 ± 0.053	1.998IleGln: 1.998 ± 0.044	3.096IleArg: 3.096 ± 0.051	3.979IleSer: 3.979 ± 0.06	3.597IleThr: 3.597 ± 0.057	4.033IleVal: 4.033 ± 0.07	0.745IleTrp: 0.745 ± 0.027	1.539IleTyr: 1.539 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	3.967LysAla: 3.967 ± 0.065	0.235LysCys: 0.235 ± 0.014	2.02LysAsp: 2.02 ± 0.048	2.353LysGlu: 2.353 ± 0.048	1.096LysPhe: 1.096 ± 0.032	2.951LysGly: 2.951 ± 0.055	0.841LysHis: 0.841 ± 0.027	2.367LysIle: 2.367 ± 0.048	2.163LysLys: 2.163 ± 0.054	4.285LysLeu: 4.285 ± 0.07	1.217LysMet: 1.217 ± 0.031	1.766LysAsn: 1.766 ± 0.047	2.083LysPro: 2.083 ± 0.048	2.092LysGln: 2.092 ± 0.048	2.551LysArg: 2.551 ± 0.052	2.449LysSer: 2.449 ± 0.049	2.469LysThr: 2.469 ± 0.047	2.823LysVal: 2.823 ± 0.057	0.466LysTrp: 0.466 ± 0.024	1.072LysTyr: 1.072 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	11.284LeuAla: 11.284 ± 0.139	1.205LeuCys: 1.205 ± 0.034	5.587LeuAsp: 5.587 ± 0.077	5.434LeuGlu: 5.434 ± 0.083	4.411LeuPhe: 4.411 ± 0.089	7.343LeuGly: 7.343 ± 0.105	2.439LeuHis: 2.439 ± 0.043	6.131LeuIle: 6.131 ± 0.084	4.549LeuLys: 4.549 ± 0.071	12.493LeuLeu: 12.493 ± 0.177	2.947LeuMet: 2.947 ± 0.064	4.448LeuAsn: 4.448 ± 0.068	5.831LeuPro: 5.831 ± 0.084	4.588LeuGln: 4.588 ± 0.064	6.294LeuArg: 6.294 ± 0.085	7.878LeuSer: 7.878 ± 0.082	6.343LeuThr: 6.343 ± 0.079	7.106LeuVal: 7.106 ± 0.101	1.399LeuTrp: 1.399 ± 0.036	2.659LeuTyr: 2.659 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	2.887MetAla: 2.887 ± 0.049	0.182MetCys: 0.182 ± 0.015	1.191MetAsp: 1.191 ± 0.033	1.221MetGlu: 1.221 ± 0.033	0.833MetPhe: 0.833 ± 0.025	1.801MetGly: 1.801 ± 0.043	0.586MetHis: 0.586 ± 0.025	1.531MetIle: 1.531 ± 0.039	1.389MetLys: 1.389 ± 0.039	3.353MetLeu: 3.353 ± 0.056	0.918MetMet: 0.918 ± 0.029	1.12MetAsn: 1.12 ± 0.036	1.376MetPro: 1.376 ± 0.038	1.227MetGln: 1.227 ± 0.031	1.585MetArg: 1.585 ± 0.04	1.897MetSer: 1.897 ± 0.046	1.738MetThr: 1.738 ± 0.039	1.865MetVal: 1.865 ± 0.04	0.245MetTrp: 0.245 ± 0.014	0.489MetTyr: 0.489 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.643AsnAla: 3.643 ± 0.058	0.325AsnCys: 0.325 ± 0.017	2.13AsnAsp: 2.13 ± 0.045	1.834AsnGlu: 1.834 ± 0.039	1.298AsnPhe: 1.298 ± 0.036	3.004AsnGly: 3.004 ± 0.062	0.908AsnHis: 0.908 ± 0.027	2.43AsnIle: 2.43 ± 0.045	1.614AsnLys: 1.614 ± 0.037	3.605AsnLeu: 3.605 ± 0.065	0.983AsnMet: 0.983 ± 0.027	1.724AsnAsn: 1.724 ± 0.052	2.102AsnPro: 2.102 ± 0.045	1.718AsnGln: 1.718 ± 0.039	2.141AsnArg: 2.141 ± 0.041	2.231AsnSer: 2.231 ± 0.056	2.029AsnThr: 2.029 ± 0.043	2.613AsnVal: 2.613 ± 0.06	0.586AsnTrp: 0.586 ± 0.026	1.192AsnTyr: 1.192 ± 0.036	0.0AsnXaa: 0.0 ± 0.0
Pro	4.344ProAla: 4.344 ± 0.068	0.352ProCys: 0.352 ± 0.016	2.8ProAsp: 2.8 ± 0.056	3.234ProGlu: 3.234 ± 0.06	1.804ProPhe: 1.804 ± 0.042	3.449ProGly: 3.449 ± 0.063	1.129ProHis: 1.129 ± 0.032	2.01ProIle: 2.01 ± 0.043	1.481ProLys: 1.481 ± 0.048	5.207ProLeu: 5.207 ± 0.072	1.126ProMet: 1.126 ± 0.035	1.31ProAsn: 1.31 ± 0.033	1.714ProPro: 1.714 ± 0.046	2.259ProGln: 2.259 ± 0.053	1.958ProArg: 1.958 ± 0.048	2.213ProSer: 2.213 ± 0.042	2.121ProThr: 2.121 ± 0.049	3.726ProVal: 3.726 ± 0.064	0.727ProTrp: 0.727 ± 0.026	1.199ProTyr: 1.199 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.589GlnAla: 4.589 ± 0.08	0.361GlnCys: 0.361 ± 0.017	1.974GlnAsp: 1.974 ± 0.045	2.047GlnGlu: 2.047 ± 0.048	1.493GlnPhe: 1.493 ± 0.041	3.154GlnGly: 3.154 ± 0.062	1.443GlnHis: 1.443 ± 0.041	2.402GlnIle: 2.402 ± 0.05	1.774GlnLys: 1.774 ± 0.037	5.311GlnLeu: 5.311 ± 0.079	1.185GlnMet: 1.185 ± 0.031	1.441GlnAsn: 1.441 ± 0.035	2.338GlnPro: 2.338 ± 0.048	4.0GlnGln: 4.0 ± 0.102	3.418GlnArg: 3.418 ± 0.061	2.457GlnSer: 2.457 ± 0.049	2.146GlnThr: 2.146 ± 0.043	2.997GlnVal: 2.997 ± 0.05	0.703GlnTrp: 0.703 ± 0.03	1.167GlnTyr: 1.167 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	4.686ArgAla: 4.686 ± 0.069	0.626ArgCys: 0.626 ± 0.022	3.099ArgAsp: 3.099 ± 0.058	3.745ArgGlu: 3.745 ± 0.065	2.629ArgPhe: 2.629 ± 0.051	3.467ArgGly: 3.467 ± 0.057	1.611ArgHis: 1.611 ± 0.039	3.697ArgIle: 3.697 ± 0.052	2.297ArgLys: 2.297 ± 0.044	6.636ArgLeu: 6.636 ± 0.1	1.578ArgMet: 1.578 ± 0.041	2.125ArgAsn: 2.125 ± 0.039	2.273ArgPro: 2.273 ± 0.044	3.265ArgGln: 3.265 ± 0.054	3.569ArgArg: 3.569 ± 0.063	2.913ArgSer: 2.913 ± 0.05	2.519ArgThr: 2.519 ± 0.046	3.848ArgVal: 3.848 ± 0.063	0.949ArgTrp: 0.949 ± 0.033	2.188ArgTyr: 2.188 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	5.784SerAla: 5.784 ± 0.076	0.571SerCys: 0.571 ± 0.025	3.421SerAsp: 3.421 ± 0.132	3.265SerGlu: 3.265 ± 0.047	2.404SerPhe: 2.404 ± 0.049	5.618SerGly: 5.618 ± 0.079	1.509SerHis: 1.509 ± 0.038	3.258SerIle: 3.258 ± 0.058	2.059SerLys: 2.059 ± 0.048	7.18SerLeu: 7.18 ± 0.095	1.566SerMet: 1.566 ± 0.039	2.054SerAsn: 2.054 ± 0.052	2.739SerPro: 2.739 ± 0.052	2.683SerGln: 2.683 ± 0.052	3.553SerArg: 3.553 ± 0.06	3.823SerSer: 3.823 ± 0.069	3.126SerThr: 3.126 ± 0.052	4.312SerVal: 4.312 ± 0.065	0.996SerTrp: 0.996 ± 0.033	1.586SerTyr: 1.586 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	4.899ThrAla: 4.899 ± 0.076	0.488ThrCys: 0.488 ± 0.023	2.588ThrAsp: 2.588 ± 0.052	2.552ThrGlu: 2.552 ± 0.048	2.034ThrPhe: 2.034 ± 0.048	4.286ThrGly: 4.286 ± 0.063	1.313ThrHis: 1.313 ± 0.034	2.874ThrIle: 2.874 ± 0.056	1.526ThrLys: 1.526 ± 0.04	7.682ThrLeu: 7.682 ± 0.09	1.121ThrMet: 1.121 ± 0.032	1.499ThrAsn: 1.499 ± 0.032	3.071ThrPro: 3.071 ± 0.052	2.252ThrGln: 2.252 ± 0.045	3.156ThrArg: 3.156 ± 0.057	2.985ThrSer: 2.985 ± 0.055	2.723ThrThr: 2.723 ± 0.057	3.698ThrVal: 3.698 ± 0.064	0.702ThrTrp: 0.702 ± 0.024	1.08ThrTyr: 1.08 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	6.768ValAla: 6.768 ± 0.08	0.69ValCys: 0.69 ± 0.02	3.623ValAsp: 3.623 ± 0.064	3.859ValGlu: 3.859 ± 0.062	2.508ValPhe: 2.508 ± 0.053	4.753ValGly: 4.753 ± 0.072	1.263ValHis: 1.263 ± 0.036	4.676ValIle: 4.676 ± 0.069	2.981ValLys: 2.981 ± 0.055	7.328ValLeu: 7.328 ± 0.092	2.153ValMet: 2.153 ± 0.045	2.779ValAsn: 2.779 ± 0.054	2.926ValPro: 2.926 ± 0.056	2.331ValGln: 2.331 ± 0.046	3.551ValArg: 3.551 ± 0.056	4.598ValSer: 4.598 ± 0.067	4.095ValThr: 4.095 ± 0.061	5.173ValVal: 5.173 ± 0.073	0.896ValTrp: 0.896 ± 0.028	1.564ValTyr: 1.564 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	0.953TrpAla: 0.953 ± 0.029	0.182TrpCys: 0.182 ± 0.013	0.604TrpAsp: 0.604 ± 0.026	0.562TrpGlu: 0.562 ± 0.024	0.658TrpPhe: 0.658 ± 0.027	0.87TrpGly: 0.87 ± 0.031	0.463TrpHis: 0.463 ± 0.021	0.792TrpIle: 0.792 ± 0.024	0.536TrpLys: 0.536 ± 0.018	2.356TrpLeu: 2.356 ± 0.055	0.406TrpMet: 0.406 ± 0.019	0.457TrpAsn: 0.457 ± 0.02	0.659TrpPro: 0.659 ± 0.028	1.232TrpGln: 1.232 ± 0.039	1.031TrpArg: 1.031 ± 0.039	0.811TrpSer: 0.811 ± 0.025	0.526TrpThr: 0.526 ± 0.023	0.9TrpVal: 0.9 ± 0.031	0.213TrpTrp: 0.213 ± 0.014	0.421TrpTyr: 0.421 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.445TyrAla: 2.445 ± 0.055	0.379TyrCys: 0.379 ± 0.02	1.538TyrAsp: 1.538 ± 0.041	1.093TyrGlu: 1.093 ± 0.03	1.137TyrPhe: 1.137 ± 0.029	2.21TyrGly: 2.21 ± 0.044	0.746TyrHis: 0.746 ± 0.029	1.435TyrIle: 1.435 ± 0.036	0.903TyrLys: 0.903 ± 0.031	3.008TyrLeu: 3.008 ± 0.054	0.577TyrMet: 0.577 ± 0.022	0.989TyrAsn: 0.989 ± 0.036	1.362TyrPro: 1.362 ± 0.033	1.673TyrGln: 1.673 ± 0.045	1.867TyrArg: 1.867 ± 0.043	1.707TyrSer: 1.707 ± 0.042	1.31TyrThr: 1.31 ± 0.037	1.645TyrVal: 1.645 ± 0.043	0.432TyrTrp: 0.432 ± 0.02	0.888TyrTyr: 0.888 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3521 proteins (1141336 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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