Amino acid dipepetide frequency for Tortoise microvirus 37

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.152AlaAla: 6.152 ± 1.266
0.559AlaCys: 0.559 ± 0.487
6.152AlaAsp: 6.152 ± 1.297
5.593AlaGlu: 5.593 ± 2.512
5.593AlaPhe: 5.593 ± 1.68
3.356AlaGly: 3.356 ± 1.551
2.237AlaHis: 2.237 ± 0.69
5.034AlaIle: 5.034 ± 1.411
7.83AlaLys: 7.83 ± 1.953
8.389AlaLeu: 8.389 ± 3.672
2.796AlaMet: 2.796 ± 1.049
1.678AlaAsn: 1.678 ± 1.081
2.796AlaPro: 2.796 ± 0.687
1.678AlaGln: 1.678 ± 0.824
6.711AlaArg: 6.711 ± 1.125
2.796AlaSer: 2.796 ± 1.364
4.474AlaThr: 4.474 ± 1.5
7.271AlaVal: 7.271 ± 1.946
0.559AlaTrp: 0.559 ± 0.563
3.356AlaTyr: 3.356 ± 1.224
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.559CysAsp: 0.559 ± 0.405
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.119CysGly: 1.119 ± 1.127
0.559CysHis: 0.559 ± 0.563
1.119CysIle: 1.119 ± 0.974
0.559CysLys: 0.559 ± 0.522
0.559CysLeu: 0.559 ± 0.487
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.119CysGln: 1.119 ± 0.974
3.356CysArg: 3.356 ± 1.383
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.593AspAla: 5.593 ± 1.099
0.0AspCys: 0.0 ± 0.0
5.034AspAsp: 5.034 ± 1.704
1.678AspGlu: 1.678 ± 0.73
1.678AspPhe: 1.678 ± 0.703
2.237AspGly: 2.237 ± 0.82
1.119AspHis: 1.119 ± 0.69
3.356AspIle: 3.356 ± 1.335
1.678AspLys: 1.678 ± 0.94
7.271AspLeu: 7.271 ± 1.38
1.119AspMet: 1.119 ± 0.535
2.237AspAsn: 2.237 ± 1.017
3.356AspPro: 3.356 ± 1.449
5.034AspGln: 5.034 ± 1.826
5.034AspArg: 5.034 ± 1.246
1.678AspSer: 1.678 ± 0.671
5.593AspThr: 5.593 ± 0.88
2.237AspVal: 2.237 ± 0.682
2.237AspTrp: 2.237 ± 1.192
4.474AspTyr: 4.474 ± 1.202
0.0AspXaa: 0.0 ± 0.0
Glu
4.474GluAla: 4.474 ± 1.123
1.119GluCys: 1.119 ± 0.974
2.796GluAsp: 2.796 ± 0.934
1.678GluGlu: 1.678 ± 0.878
1.119GluPhe: 1.119 ± 0.861
3.915GluGly: 3.915 ± 1.257
2.796GluHis: 2.796 ± 0.737
3.915GluIle: 3.915 ± 1.219
2.237GluLys: 2.237 ± 0.952
4.474GluLeu: 4.474 ± 1.617
2.237GluMet: 2.237 ± 0.84
2.796GluAsn: 2.796 ± 1.346
2.796GluPro: 2.796 ± 1.284
1.678GluGln: 1.678 ± 0.553
3.915GluArg: 3.915 ± 1.122
2.237GluSer: 2.237 ± 1.245
2.796GluThr: 2.796 ± 1.04
5.593GluVal: 5.593 ± 1.705
1.678GluTrp: 1.678 ± 1.022
1.678GluTyr: 1.678 ± 1.461
0.0GluXaa: 0.0 ± 0.0
Phe
3.356PheAla: 3.356 ± 1.121
0.559PheCys: 0.559 ± 0.487
1.678PheAsp: 1.678 ± 1.216
2.237PheGlu: 2.237 ± 0.728
2.237PhePhe: 2.237 ± 0.671
3.915PheGly: 3.915 ± 1.909
0.559PheHis: 0.559 ± 0.487
1.119PheIle: 1.119 ± 0.974
1.678PheLys: 1.678 ± 0.94
2.796PheLeu: 2.796 ± 1.135
1.119PheMet: 1.119 ± 0.582
2.796PheAsn: 2.796 ± 0.902
1.678PhePro: 1.678 ± 0.751
2.237PheGln: 2.237 ± 1.336
2.796PheArg: 2.796 ± 1.023
1.678PheSer: 1.678 ± 1.113
1.119PheThr: 1.119 ± 0.765
2.237PheVal: 2.237 ± 0.8
2.796PheTrp: 2.796 ± 1.551
1.119PheTyr: 1.119 ± 0.861
0.0PheXaa: 0.0 ± 0.0
Gly
6.152GlyAla: 6.152 ± 1.438
0.0GlyCys: 0.0 ± 0.0
2.237GlyAsp: 2.237 ± 0.875
3.356GlyGlu: 3.356 ± 2.009
4.474GlyPhe: 4.474 ± 0.943
11.745GlyGly: 11.745 ± 4.028
1.119GlyHis: 1.119 ± 0.783
5.593GlyIle: 5.593 ± 2.051
4.474GlyLys: 4.474 ± 1.079
5.593GlyLeu: 5.593 ± 1.948
5.034GlyMet: 5.034 ± 1.752
1.119GlyAsn: 1.119 ± 0.861
3.915GlyPro: 3.915 ± 2.095
4.474GlyGln: 4.474 ± 1.548
5.034GlyArg: 5.034 ± 1.69
6.152GlySer: 6.152 ± 1.614
5.034GlyThr: 5.034 ± 1.24
5.034GlyVal: 5.034 ± 1.666
1.678GlyTrp: 1.678 ± 0.751
2.237GlyTyr: 2.237 ± 0.558
0.0GlyXaa: 0.0 ± 0.0
His
1.678HisAla: 1.678 ± 0.751
0.559HisCys: 0.559 ± 0.522
0.0HisAsp: 0.0 ± 0.0
0.559HisGlu: 0.559 ± 0.681
2.237HisPhe: 2.237 ± 0.952
1.119HisGly: 1.119 ± 0.974
0.0HisHis: 0.0 ± 0.0
1.119HisIle: 1.119 ± 0.811
0.0HisLys: 0.0 ± 0.0
1.119HisLeu: 1.119 ± 0.67
0.559HisMet: 0.559 ± 0.405
1.119HisAsn: 1.119 ± 0.798
2.796HisPro: 2.796 ± 1.042
0.559HisGln: 0.559 ± 0.487
0.559HisArg: 0.559 ± 0.563
1.119HisSer: 1.119 ± 0.811
1.678HisThr: 1.678 ± 1.238
1.678HisVal: 1.678 ± 0.743
1.678HisTrp: 1.678 ± 0.968
1.119HisTyr: 1.119 ± 0.535
0.0HisXaa: 0.0 ± 0.0
Ile
2.796IleAla: 2.796 ± 1.586
0.559IleCys: 0.559 ± 0.563
3.356IleAsp: 3.356 ± 1.285
1.678IleGlu: 1.678 ± 0.699
0.559IlePhe: 0.559 ± 0.563
5.593IleGly: 5.593 ± 1.658
0.559IleHis: 0.559 ± 0.573
1.678IleIle: 1.678 ± 0.815
2.237IleLys: 2.237 ± 1.164
1.678IleLeu: 1.678 ± 0.824
0.0IleMet: 0.0 ± 0.0
1.678IleAsn: 1.678 ± 0.824
2.796IlePro: 2.796 ± 1.107
1.119IleGln: 1.119 ± 0.582
4.474IleArg: 4.474 ± 1.446
1.119IleSer: 1.119 ± 0.64
3.915IleThr: 3.915 ± 1.377
7.83IleVal: 7.83 ± 2.505
0.0IleTrp: 0.0 ± 0.0
1.119IleTyr: 1.119 ± 0.535
0.0IleXaa: 0.0 ± 0.0
Lys
6.152LysAla: 6.152 ± 1.624
0.559LysCys: 0.559 ± 0.487
4.474LysAsp: 4.474 ± 1.669
2.237LysGlu: 2.237 ± 0.837
1.678LysPhe: 1.678 ± 0.878
2.796LysGly: 2.796 ± 1.155
1.119LysHis: 1.119 ± 0.687
1.678LysIle: 1.678 ± 0.968
3.356LysLys: 3.356 ± 0.749
2.796LysLeu: 2.796 ± 1.126
0.559LysMet: 0.559 ± 0.487
1.678LysAsn: 1.678 ± 1.113
3.356LysPro: 3.356 ± 0.991
1.678LysGln: 1.678 ± 0.751
2.796LysArg: 2.796 ± 1.469
2.796LysSer: 2.796 ± 1.558
4.474LysThr: 4.474 ± 1.581
0.559LysVal: 0.559 ± 0.487
1.678LysTrp: 1.678 ± 0.94
2.237LysTyr: 2.237 ± 1.064
0.0LysXaa: 0.0 ± 0.0
Leu
10.067LeuAla: 10.067 ± 1.897
0.559LeuCys: 0.559 ± 0.487
5.593LeuAsp: 5.593 ± 1.463
4.474LeuGlu: 4.474 ± 1.789
2.796LeuPhe: 2.796 ± 0.925
7.83LeuGly: 7.83 ± 3.97
1.119LeuHis: 1.119 ± 0.811
1.678LeuIle: 1.678 ± 0.782
2.796LeuLys: 2.796 ± 0.782
6.711LeuLeu: 6.711 ± 1.43
2.796LeuMet: 2.796 ± 0.774
2.796LeuAsn: 2.796 ± 1.367
6.711LeuPro: 6.711 ± 2.452
1.678LeuGln: 1.678 ± 0.553
5.593LeuArg: 5.593 ± 0.852
3.915LeuSer: 3.915 ± 1.321
3.915LeuThr: 3.915 ± 1.291
4.474LeuVal: 4.474 ± 1.381
1.119LeuTrp: 1.119 ± 0.829
1.678LeuTyr: 1.678 ± 1.026
0.0LeuXaa: 0.0 ± 0.0
Met
3.915MetAla: 3.915 ± 0.845
0.559MetCys: 0.559 ± 0.487
1.678MetAsp: 1.678 ± 0.824
2.237MetGlu: 2.237 ± 0.861
0.0MetPhe: 0.0 ± 0.0
3.915MetGly: 3.915 ± 1.574
0.559MetHis: 0.559 ± 0.681
0.0MetIle: 0.0 ± 0.0
1.119MetLys: 1.119 ± 0.69
0.559MetLeu: 0.559 ± 0.674
0.0MetMet: 0.0 ± 0.0
1.119MetAsn: 1.119 ± 1.348
1.678MetPro: 1.678 ± 0.815
1.678MetGln: 1.678 ± 0.824
2.237MetArg: 2.237 ± 0.82
3.356MetSer: 3.356 ± 1.316
0.559MetThr: 0.559 ± 0.563
1.678MetVal: 1.678 ± 1.238
1.119MetTrp: 1.119 ± 0.85
0.559MetTyr: 0.559 ± 0.563
0.0MetXaa: 0.0 ± 0.0
Asn
5.034AsnAla: 5.034 ± 2.729
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
5.034AsnGlu: 5.034 ± 1.277
1.678AsnPhe: 1.678 ± 0.759
4.474AsnGly: 4.474 ± 1.676
0.0AsnHis: 0.0 ± 0.0
2.237AsnIle: 2.237 ± 1.16
0.0AsnLys: 0.0 ± 0.0
1.678AsnLeu: 1.678 ± 1.081
1.119AsnMet: 1.119 ± 0.783
1.678AsnAsn: 1.678 ± 1.192
2.796AsnPro: 2.796 ± 1.107
0.559AsnGln: 0.559 ± 0.573
3.915AsnArg: 3.915 ± 0.972
1.678AsnSer: 1.678 ± 0.699
0.559AsnThr: 0.559 ± 0.405
2.237AsnVal: 2.237 ± 1.193
1.678AsnTrp: 1.678 ± 1.081
1.678AsnTyr: 1.678 ± 2.022
0.0AsnXaa: 0.0 ± 0.0
Pro
4.474ProAla: 4.474 ± 1.438
0.559ProCys: 0.559 ± 0.563
6.152ProAsp: 6.152 ± 1.365
4.474ProGlu: 4.474 ± 1.684
2.796ProPhe: 2.796 ± 0.706
5.034ProGly: 5.034 ± 2.587
2.237ProHis: 2.237 ± 0.679
0.559ProIle: 0.559 ± 0.405
2.237ProLys: 2.237 ± 0.818
7.271ProLeu: 7.271 ± 1.383
2.237ProMet: 2.237 ± 1.484
2.237ProAsn: 2.237 ± 1.053
3.915ProPro: 3.915 ± 1.575
1.678ProGln: 1.678 ± 0.507
3.915ProArg: 3.915 ± 1.494
2.796ProSer: 2.796 ± 1.107
2.796ProThr: 2.796 ± 2.089
5.034ProVal: 5.034 ± 1.667
0.0ProTrp: 0.0 ± 0.0
2.796ProTyr: 2.796 ± 0.934
0.0ProXaa: 0.0 ± 0.0
Gln
3.915GlnAla: 3.915 ± 0.982
0.559GlnCys: 0.559 ± 0.405
2.237GlnAsp: 2.237 ± 0.839
3.356GlnGlu: 3.356 ± 1.544
2.237GlnPhe: 2.237 ± 1.213
2.237GlnGly: 2.237 ± 0.8
1.119GlnHis: 1.119 ± 0.535
1.119GlnIle: 1.119 ± 0.67
2.796GlnLys: 2.796 ± 0.782
2.796GlnLeu: 2.796 ± 1.399
0.0GlnMet: 0.0 ± 0.0
2.237GlnAsn: 2.237 ± 0.728
3.356GlnPro: 3.356 ± 2.009
1.678GlnGln: 1.678 ± 0.759
3.356GlnArg: 3.356 ± 1.398
2.796GlnSer: 2.796 ± 1.371
0.559GlnThr: 0.559 ± 0.573
2.237GlnVal: 2.237 ± 1.092
0.559GlnTrp: 0.559 ± 0.573
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.593ArgAla: 5.593 ± 1.891
1.119ArgCys: 1.119 ± 0.535
6.152ArgAsp: 6.152 ± 1.712
4.474ArgGlu: 4.474 ± 1.326
2.796ArgPhe: 2.796 ± 0.741
5.034ArgGly: 5.034 ± 1.966
1.678ArgHis: 1.678 ± 0.703
3.915ArgIle: 3.915 ± 1.014
5.593ArgLys: 5.593 ± 1.41
4.474ArgLeu: 4.474 ± 1.418
1.678ArgMet: 1.678 ± 0.878
2.796ArgAsn: 2.796 ± 0.851
3.356ArgPro: 3.356 ± 1.007
4.474ArgGln: 4.474 ± 1.043
4.474ArgArg: 4.474 ± 1.874
2.796ArgSer: 2.796 ± 1.011
2.796ArgThr: 2.796 ± 0.931
5.034ArgVal: 5.034 ± 1.576
0.559ArgTrp: 0.559 ± 0.674
3.356ArgTyr: 3.356 ± 1.325
0.0ArgXaa: 0.0 ± 0.0
Ser
2.237SerAla: 2.237 ± 0.69
1.119SerCys: 1.119 ± 0.593
3.915SerAsp: 3.915 ± 1.443
2.796SerGlu: 2.796 ± 0.925
1.678SerPhe: 1.678 ± 0.94
6.152SerGly: 6.152 ± 1.318
0.0SerHis: 0.0 ± 0.0
5.034SerIle: 5.034 ± 2.712
2.237SerLys: 2.237 ± 0.69
3.915SerLeu: 3.915 ± 1.377
0.559SerMet: 0.559 ± 0.573
2.237SerAsn: 2.237 ± 1.193
3.356SerPro: 3.356 ± 1.636
1.119SerGln: 1.119 ± 1.348
2.237SerArg: 2.237 ± 0.558
1.678SerSer: 1.678 ± 1.081
2.796SerThr: 2.796 ± 1.161
4.474SerVal: 4.474 ± 1.302
1.119SerTrp: 1.119 ± 0.64
1.119SerTyr: 1.119 ± 0.67
0.0SerXaa: 0.0 ± 0.0
Thr
2.237ThrAla: 2.237 ± 0.84
0.0ThrCys: 0.0 ± 0.0
3.915ThrAsp: 3.915 ± 1.061
3.915ThrGlu: 3.915 ± 0.785
1.119ThrPhe: 1.119 ± 0.811
5.034ThrGly: 5.034 ± 1.797
0.559ThrHis: 0.559 ± 0.522
2.237ThrIle: 2.237 ± 0.864
2.237ThrLys: 2.237 ± 1.621
7.271ThrLeu: 7.271 ± 1.702
2.796ThrMet: 2.796 ± 0.736
1.119ThrAsn: 1.119 ± 0.535
4.474ThrPro: 4.474 ± 1.326
0.0ThrGln: 0.0 ± 0.0
1.678ThrArg: 1.678 ± 0.87
3.915ThrSer: 3.915 ± 1.163
6.711ThrThr: 6.711 ± 1.992
3.915ThrVal: 3.915 ± 0.783
1.119ThrTrp: 1.119 ± 0.783
2.237ThrTyr: 2.237 ± 0.99
0.0ThrXaa: 0.0 ± 0.0
Val
5.593ValAla: 5.593 ± 2.847
0.559ValCys: 0.559 ± 0.563
4.474ValAsp: 4.474 ± 0.732
3.915ValGlu: 3.915 ± 1.81
3.356ValPhe: 3.356 ± 1.272
3.915ValGly: 3.915 ± 0.672
1.678ValHis: 1.678 ± 0.507
1.119ValIle: 1.119 ± 0.809
3.356ValLys: 3.356 ± 1.164
3.356ValLeu: 3.356 ± 1.397
2.237ValMet: 2.237 ± 0.728
3.356ValAsn: 3.356 ± 1.088
7.271ValPro: 7.271 ± 1.801
5.593ValGln: 5.593 ± 2.929
6.152ValArg: 6.152 ± 0.876
3.356ValSer: 3.356 ± 0.774
4.474ValThr: 4.474 ± 1.621
3.356ValVal: 3.356 ± 1.043
0.559ValTrp: 0.559 ± 0.563
1.119ValTyr: 1.119 ± 0.606
0.0ValXaa: 0.0 ± 0.0
Trp
3.356TrpAla: 3.356 ± 1.247
0.0TrpCys: 0.0 ± 0.0
1.119TrpAsp: 1.119 ± 1.045
1.119TrpGlu: 1.119 ± 0.527
0.559TrpPhe: 0.559 ± 0.522
1.119TrpGly: 1.119 ± 0.829
1.678TrpHis: 1.678 ± 1.461
1.119TrpIle: 1.119 ± 0.582
1.119TrpLys: 1.119 ± 0.809
2.237TrpLeu: 2.237 ± 0.826
0.0TrpMet: 0.0 ± 0.0
2.237TrpAsn: 2.237 ± 1.053
1.119TrpPro: 1.119 ± 0.64
0.0TrpGln: 0.0 ± 0.0
1.678TrpArg: 1.678 ± 0.94
1.119TrpSer: 1.119 ± 0.687
1.119TrpThr: 1.119 ± 1.127
0.559TrpVal: 0.559 ± 0.674
0.559TrpTrp: 0.559 ± 0.487
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.237TyrAla: 2.237 ± 1.07
0.0TyrCys: 0.0 ± 0.0
1.119TyrAsp: 1.119 ± 1.348
1.119TyrGlu: 1.119 ± 0.535
1.119TyrPhe: 1.119 ± 0.64
3.915TyrGly: 3.915 ± 1.951
0.559TyrHis: 0.559 ± 0.563
1.119TyrIle: 1.119 ± 0.829
1.119TyrLys: 1.119 ± 0.811
3.356TyrLeu: 3.356 ± 1.276
1.119TyrMet: 1.119 ± 0.536
1.119TyrAsn: 1.119 ± 0.527
2.237TyrPro: 2.237 ± 1.529
1.119TyrGln: 1.119 ± 0.781
2.237TyrArg: 2.237 ± 0.861
2.796TyrSer: 2.796 ± 1.25
1.119TyrThr: 1.119 ± 0.535
3.356TyrVal: 3.356 ± 1.362
1.119TyrTrp: 1.119 ± 0.765
0.559TyrTyr: 0.559 ± 0.405
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1789 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski