Amino acid dipepetide frequency for Fowl aviadenovirus E

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.532AlaAla: 8.532 ± 2.019
0.948AlaCys: 0.948 ± 0.377
3.318AlaAsp: 3.318 ± 0.426
4.819AlaGlu: 4.819 ± 1.052
2.37AlaPhe: 2.37 ± 0.323
4.74AlaGly: 4.74 ± 0.784
1.422AlaHis: 1.422 ± 0.411
3.792AlaIle: 3.792 ± 0.673
2.449AlaLys: 2.449 ± 0.539
7.505AlaLeu: 7.505 ± 0.776
2.054AlaMet: 2.054 ± 0.529
3.002AlaAsn: 3.002 ± 0.579
6.083AlaPro: 6.083 ± 0.846
3.318AlaGln: 3.318 ± 0.612
4.108AlaArg: 4.108 ± 0.811
5.609AlaSer: 5.609 ± 0.779
4.898AlaThr: 4.898 ± 0.858
7.347AlaVal: 7.347 ± 0.77
0.869AlaTrp: 0.869 ± 0.303
3.002AlaTyr: 3.002 ± 0.546
0.0AlaXaa: 0.0 ± 0.0
Cys
0.869CysAla: 0.869 ± 0.29
0.395CysCys: 0.395 ± 0.178
1.106CysAsp: 1.106 ± 0.284
0.316CysGlu: 0.316 ± 0.142
0.711CysPhe: 0.711 ± 0.221
1.58CysGly: 1.58 ± 0.377
0.711CysHis: 0.711 ± 0.341
0.474CysIle: 0.474 ± 0.185
0.553CysLys: 0.553 ± 0.248
1.896CysLeu: 1.896 ± 0.517
0.711CysMet: 0.711 ± 0.242
0.869CysAsn: 0.869 ± 0.313
1.659CysPro: 1.659 ± 0.386
0.632CysGln: 0.632 ± 0.259
1.58CysArg: 1.58 ± 0.346
1.343CysSer: 1.343 ± 0.334
0.948CysThr: 0.948 ± 0.308
1.264CysVal: 1.264 ± 0.407
0.474CysTrp: 0.474 ± 0.177
0.711CysTyr: 0.711 ± 0.24
0.0CysXaa: 0.0 ± 0.0
Asp
4.029AspAla: 4.029 ± 0.629
0.474AspCys: 0.474 ± 0.206
3.397AspAsp: 3.397 ± 0.647
3.634AspGlu: 3.634 ± 0.798
2.686AspPhe: 2.686 ± 0.525
4.029AspGly: 4.029 ± 0.704
0.948AspHis: 0.948 ± 0.254
2.37AspIle: 2.37 ± 0.629
1.422AspLys: 1.422 ± 0.34
4.661AspLeu: 4.661 ± 0.665
0.79AspMet: 0.79 ± 0.241
1.738AspAsn: 1.738 ± 0.516
4.819AspPro: 4.819 ± 0.805
1.817AspGln: 1.817 ± 0.332
3.95AspArg: 3.95 ± 0.656
4.345AspSer: 4.345 ± 0.501
3.318AspThr: 3.318 ± 0.554
3.002AspVal: 3.002 ± 0.51
0.395AspTrp: 0.395 ± 0.162
2.37AspTyr: 2.37 ± 0.355
0.0AspXaa: 0.0 ± 0.0
Glu
3.95GluAla: 3.95 ± 0.444
0.395GluCys: 0.395 ± 0.174
3.555GluAsp: 3.555 ± 0.749
7.742GluGlu: 7.742 ± 1.891
1.817GluPhe: 1.817 ± 0.578
4.029GluGly: 4.029 ± 0.55
1.501GluHis: 1.501 ± 0.348
1.975GluIle: 1.975 ± 0.368
2.054GluLys: 2.054 ± 0.473
5.293GluLeu: 5.293 ± 0.555
1.185GluMet: 1.185 ± 0.355
2.528GluAsn: 2.528 ± 0.47
3.16GluPro: 3.16 ± 0.538
2.133GluGln: 2.133 ± 0.54
4.345GluArg: 4.345 ± 0.72
3.792GluSer: 3.792 ± 0.611
2.923GluThr: 2.923 ± 0.376
3.239GluVal: 3.239 ± 0.547
0.711GluTrp: 0.711 ± 0.24
1.58GluTyr: 1.58 ± 0.355
0.0GluXaa: 0.0 ± 0.0
Phe
2.844PheAla: 2.844 ± 0.507
0.474PheCys: 0.474 ± 0.184
2.37PheAsp: 2.37 ± 0.502
2.133PheGlu: 2.133 ± 0.375
2.133PhePhe: 2.133 ± 0.374
1.975PheGly: 1.975 ± 0.375
1.422PheHis: 1.422 ± 0.341
1.106PheIle: 1.106 ± 0.333
1.343PheLys: 1.343 ± 0.292
3.634PheLeu: 3.634 ± 0.658
1.185PheMet: 1.185 ± 0.316
2.37PheAsn: 2.37 ± 0.433
2.291PhePro: 2.291 ± 0.444
0.632PheGln: 0.632 ± 0.236
3.555PheArg: 3.555 ± 0.46
2.844PheSer: 2.844 ± 0.459
2.765PheThr: 2.765 ± 0.445
3.318PheVal: 3.318 ± 0.579
1.185PheTrp: 1.185 ± 0.361
1.817PheTyr: 1.817 ± 0.351
0.0PheXaa: 0.0 ± 0.0
Gly
6.636GlyAla: 6.636 ± 0.842
0.869GlyCys: 0.869 ± 0.31
3.792GlyAsp: 3.792 ± 0.536
4.345GlyGlu: 4.345 ± 1.049
2.37GlyPhe: 2.37 ± 0.389
8.216GlyGly: 8.216 ± 1.133
1.422GlyHis: 1.422 ± 0.427
2.133GlyIle: 2.133 ± 0.461
1.659GlyLys: 1.659 ± 0.352
4.582GlyLeu: 4.582 ± 0.602
1.738GlyMet: 1.738 ± 0.334
1.58GlyAsn: 1.58 ± 0.45
3.555GlyPro: 3.555 ± 0.587
2.528GlyGln: 2.528 ± 0.472
5.135GlyArg: 5.135 ± 0.884
5.53GlySer: 5.53 ± 0.888
4.661GlyThr: 4.661 ± 0.564
4.266GlyVal: 4.266 ± 0.794
1.027GlyTrp: 1.027 ± 0.232
2.37GlyTyr: 2.37 ± 0.468
0.0GlyXaa: 0.0 ± 0.0
His
1.817HisAla: 1.817 ± 0.441
0.79HisCys: 0.79 ± 0.274
1.106HisAsp: 1.106 ± 0.287
1.027HisGlu: 1.027 ± 0.292
0.632HisPhe: 0.632 ± 0.292
1.659HisGly: 1.659 ± 0.425
1.343HisHis: 1.343 ± 0.269
1.027HisIle: 1.027 ± 0.271
0.632HisLys: 0.632 ± 0.233
1.817HisLeu: 1.817 ± 0.439
0.553HisMet: 0.553 ± 0.251
1.185HisAsn: 1.185 ± 0.323
1.501HisPro: 1.501 ± 0.344
0.79HisGln: 0.79 ± 0.29
2.686HisArg: 2.686 ± 0.498
1.264HisSer: 1.264 ± 0.285
1.501HisThr: 1.501 ± 0.348
1.343HisVal: 1.343 ± 0.403
0.316HisTrp: 0.316 ± 0.137
1.027HisTyr: 1.027 ± 0.234
0.0HisXaa: 0.0 ± 0.0
Ile
3.476IleAla: 3.476 ± 0.646
0.869IleCys: 0.869 ± 0.278
1.896IleAsp: 1.896 ± 0.332
1.343IleGlu: 1.343 ± 0.175
1.185IlePhe: 1.185 ± 0.312
2.212IleGly: 2.212 ± 0.392
0.79IleHis: 0.79 ± 0.256
1.106IleIle: 1.106 ± 0.29
1.501IleLys: 1.501 ± 0.393
3.081IleLeu: 3.081 ± 0.558
0.237IleMet: 0.237 ± 0.148
1.501IleAsn: 1.501 ± 0.422
3.002IlePro: 3.002 ± 0.514
1.185IleGln: 1.185 ± 0.242
2.765IleArg: 2.765 ± 0.414
2.212IleSer: 2.212 ± 0.423
2.291IleThr: 2.291 ± 0.497
2.607IleVal: 2.607 ± 0.431
0.395IleTrp: 0.395 ± 0.172
1.422IleTyr: 1.422 ± 0.308
0.0IleXaa: 0.0 ± 0.0
Lys
2.528LysAla: 2.528 ± 0.556
0.553LysCys: 0.553 ± 0.176
1.58LysAsp: 1.58 ± 0.362
1.975LysGlu: 1.975 ± 0.47
1.501LysPhe: 1.501 ± 0.436
1.975LysGly: 1.975 ± 0.434
0.395LysHis: 0.395 ± 0.167
0.948LysIle: 0.948 ± 0.257
1.738LysLys: 1.738 ± 0.565
2.528LysLeu: 2.528 ± 0.495
1.027LysMet: 1.027 ± 0.354
1.501LysAsn: 1.501 ± 0.36
1.817LysPro: 1.817 ± 0.411
1.027LysGln: 1.027 ± 0.331
3.476LysArg: 3.476 ± 0.564
1.659LysSer: 1.659 ± 0.441
1.738LysThr: 1.738 ± 0.454
2.607LysVal: 2.607 ± 0.661
0.237LysTrp: 0.237 ± 0.143
1.659LysTyr: 1.659 ± 0.497
0.0LysXaa: 0.0 ± 0.0
Leu
6.636LeuAla: 6.636 ± 0.758
2.212LeuCys: 2.212 ± 0.477
4.819LeuAsp: 4.819 ± 0.656
4.187LeuGlu: 4.187 ± 0.577
4.108LeuPhe: 4.108 ± 0.556
4.582LeuGly: 4.582 ± 0.572
2.212LeuHis: 2.212 ± 0.591
2.686LeuIle: 2.686 ± 0.41
3.95LeuLys: 3.95 ± 0.562
9.085LeuLeu: 9.085 ± 1.172
2.212LeuMet: 2.212 ± 0.331
3.713LeuAsn: 3.713 ± 0.416
5.53LeuPro: 5.53 ± 0.689
4.029LeuGln: 4.029 ± 0.494
7.584LeuArg: 7.584 ± 1.29
6.004LeuSer: 6.004 ± 0.775
6.636LeuThr: 6.636 ± 0.844
4.503LeuVal: 4.503 ± 0.653
1.501LeuTrp: 1.501 ± 0.283
3.476LeuTyr: 3.476 ± 0.699
0.0LeuXaa: 0.0 ± 0.0
Met
2.212MetAla: 2.212 ± 0.477
0.158MetCys: 0.158 ± 0.112
1.659MetAsp: 1.659 ± 0.44
1.027MetGlu: 1.027 ± 0.338
1.343MetPhe: 1.343 ± 0.32
1.343MetGly: 1.343 ± 0.356
1.185MetHis: 1.185 ± 0.46
0.948MetIle: 0.948 ± 0.344
0.79MetLys: 0.79 ± 0.193
2.054MetLeu: 2.054 ± 0.404
0.474MetMet: 0.474 ± 0.18
0.632MetAsn: 0.632 ± 0.207
1.422MetPro: 1.422 ± 0.33
0.711MetGln: 0.711 ± 0.237
1.975MetArg: 1.975 ± 0.5
1.58MetSer: 1.58 ± 0.345
1.501MetThr: 1.501 ± 0.379
1.817MetVal: 1.817 ± 0.425
0.237MetTrp: 0.237 ± 0.142
1.027MetTyr: 1.027 ± 0.337
0.0MetXaa: 0.0 ± 0.0
Asn
3.081AsnAla: 3.081 ± 0.578
0.711AsnCys: 0.711 ± 0.233
2.37AsnAsp: 2.37 ± 0.515
1.501AsnGlu: 1.501 ± 0.435
1.817AsnPhe: 1.817 ± 0.491
1.975AsnGly: 1.975 ± 0.513
0.869AsnHis: 0.869 ± 0.209
1.422AsnIle: 1.422 ± 0.51
1.106AsnLys: 1.106 ± 0.311
3.239AsnLeu: 3.239 ± 0.584
0.632AsnMet: 0.632 ± 0.258
1.343AsnAsn: 1.343 ± 0.419
3.555AsnPro: 3.555 ± 0.463
1.264AsnGln: 1.264 ± 0.346
2.528AsnArg: 2.528 ± 0.494
3.081AsnSer: 3.081 ± 0.709
2.37AsnThr: 2.37 ± 0.555
3.002AsnVal: 3.002 ± 0.682
0.948AsnTrp: 0.948 ± 0.318
1.738AsnTyr: 1.738 ± 0.452
0.0AsnXaa: 0.0 ± 0.0
Pro
6.478ProAla: 6.478 ± 1.007
1.185ProCys: 1.185 ± 0.372
3.081ProAsp: 3.081 ± 0.482
4.345ProGlu: 4.345 ± 0.674
3.081ProPhe: 3.081 ± 0.587
2.923ProGly: 2.923 ± 0.438
1.975ProHis: 1.975 ± 0.361
1.817ProIle: 1.817 ± 0.392
1.975ProLys: 1.975 ± 0.475
5.846ProLeu: 5.846 ± 0.917
1.817ProMet: 1.817 ± 0.484
2.607ProAsn: 2.607 ± 0.517
7.742ProPro: 7.742 ± 1.266
2.528ProGln: 2.528 ± 0.589
4.266ProArg: 4.266 ± 0.657
5.451ProSer: 5.451 ± 0.806
4.345ProThr: 4.345 ± 0.617
4.582ProVal: 4.582 ± 0.686
0.395ProTrp: 0.395 ± 0.17
2.528ProTyr: 2.528 ± 0.449
0.0ProXaa: 0.0 ± 0.0
Gln
2.212GlnAla: 2.212 ± 0.428
0.553GlnCys: 0.553 ± 0.195
2.054GlnAsp: 2.054 ± 0.345
1.738GlnGlu: 1.738 ± 0.431
1.264GlnPhe: 1.264 ± 0.448
2.054GlnGly: 2.054 ± 0.48
0.711GlnHis: 0.711 ± 0.31
1.106GlnIle: 1.106 ± 0.32
1.027GlnLys: 1.027 ± 0.296
4.345GlnLeu: 4.345 ± 0.643
1.185GlnMet: 1.185 ± 0.34
1.896GlnAsn: 1.896 ± 0.53
1.817GlnPro: 1.817 ± 0.399
2.765GlnGln: 2.765 ± 0.889
2.923GlnArg: 2.923 ± 0.658
2.686GlnSer: 2.686 ± 0.491
2.291GlnThr: 2.291 ± 0.389
2.37GlnVal: 2.37 ± 0.556
0.869GlnTrp: 0.869 ± 0.293
1.185GlnTyr: 1.185 ± 0.414
0.0GlnXaa: 0.0 ± 0.0
Arg
5.214ArgAla: 5.214 ± 0.737
1.659ArgCys: 1.659 ± 0.41
4.503ArgAsp: 4.503 ± 0.734
4.345ArgGlu: 4.345 ± 0.592
3.476ArgPhe: 3.476 ± 0.52
6.32ArgGly: 6.32 ± 1.128
2.37ArgHis: 2.37 ± 0.572
2.607ArgIle: 2.607 ± 0.5
2.528ArgLys: 2.528 ± 0.443
7.11ArgLeu: 7.11 ± 0.867
1.975ArgMet: 1.975 ± 0.363
3.16ArgAsn: 3.16 ± 0.858
4.819ArgPro: 4.819 ± 0.722
2.686ArgGln: 2.686 ± 0.407
9.48ArgArg: 9.48 ± 1.922
5.925ArgSer: 5.925 ± 0.913
3.397ArgThr: 3.397 ± 0.541
4.819ArgVal: 4.819 ± 0.663
1.106ArgTrp: 1.106 ± 0.263
2.923ArgTyr: 2.923 ± 0.517
0.0ArgXaa: 0.0 ± 0.0
Ser
5.135SerAla: 5.135 ± 0.731
1.896SerCys: 1.896 ± 0.51
3.95SerAsp: 3.95 ± 0.758
4.503SerGlu: 4.503 ± 0.743
3.081SerPhe: 3.081 ± 0.526
6.794SerGly: 6.794 ± 0.843
1.501SerHis: 1.501 ± 0.454
2.844SerIle: 2.844 ± 0.512
2.133SerLys: 2.133 ± 0.538
5.451SerLeu: 5.451 ± 0.649
1.422SerMet: 1.422 ± 0.375
1.817SerAsn: 1.817 ± 0.376
3.792SerPro: 3.792 ± 0.706
2.528SerGln: 2.528 ± 0.528
6.952SerArg: 6.952 ± 1.148
5.53SerSer: 5.53 ± 0.86
4.661SerThr: 4.661 ± 0.823
3.871SerVal: 3.871 ± 0.515
1.027SerTrp: 1.027 ± 0.284
2.133SerTyr: 2.133 ± 0.413
0.0SerXaa: 0.0 ± 0.0
Thr
6.399ThrAla: 6.399 ± 0.686
1.501ThrCys: 1.501 ± 0.392
2.607ThrAsp: 2.607 ± 0.435
3.713ThrGlu: 3.713 ± 0.471
2.212ThrPhe: 2.212 ± 0.35
4.74ThrGly: 4.74 ± 0.691
1.185ThrHis: 1.185 ± 0.293
1.896ThrIle: 1.896 ± 0.357
1.659ThrLys: 1.659 ± 0.447
6.557ThrLeu: 6.557 ± 1.189
1.58ThrMet: 1.58 ± 0.357
2.528ThrAsn: 2.528 ± 0.629
4.345ThrPro: 4.345 ± 0.808
1.738ThrGln: 1.738 ± 0.349
3.555ThrArg: 3.555 ± 0.568
3.002ThrSer: 3.002 ± 0.53
3.081ThrThr: 3.081 ± 0.733
4.582ThrVal: 4.582 ± 0.793
0.632ThrTrp: 0.632 ± 0.274
2.686ThrTyr: 2.686 ± 0.6
0.0ThrXaa: 0.0 ± 0.0
Val
4.819ValAla: 4.819 ± 0.719
1.501ValCys: 1.501 ± 0.34
3.397ValAsp: 3.397 ± 0.486
3.081ValGlu: 3.081 ± 0.679
3.16ValPhe: 3.16 ± 0.522
4.266ValGly: 4.266 ± 0.493
0.869ValHis: 0.869 ± 0.288
2.765ValIle: 2.765 ± 0.544
1.975ValLys: 1.975 ± 0.501
6.162ValLeu: 6.162 ± 0.714
1.738ValMet: 1.738 ± 0.406
2.528ValAsn: 2.528 ± 0.551
4.898ValPro: 4.898 ± 0.74
2.686ValGln: 2.686 ± 0.543
5.372ValArg: 5.372 ± 0.669
5.451ValSer: 5.451 ± 0.764
4.424ValThr: 4.424 ± 0.843
4.503ValVal: 4.503 ± 0.76
0.632ValTrp: 0.632 ± 0.232
2.133ValTyr: 2.133 ± 0.414
0.0ValXaa: 0.0 ± 0.0
Trp
0.869TrpAla: 0.869 ± 0.351
0.395TrpCys: 0.395 ± 0.196
0.79TrpAsp: 0.79 ± 0.22
0.79TrpGlu: 0.79 ± 0.292
0.316TrpPhe: 0.316 ± 0.153
0.711TrpGly: 0.711 ± 0.223
0.316TrpHis: 0.316 ± 0.168
0.869TrpIle: 0.869 ± 0.265
0.474TrpLys: 0.474 ± 0.241
1.501TrpLeu: 1.501 ± 0.336
0.079TrpMet: 0.079 ± 0.124
0.948TrpAsn: 0.948 ± 0.334
0.553TrpPro: 0.553 ± 0.379
0.711TrpGln: 0.711 ± 0.221
1.027TrpArg: 1.027 ± 0.28
1.185TrpSer: 1.185 ± 0.29
0.79TrpThr: 0.79 ± 0.222
0.632TrpVal: 0.632 ± 0.197
0.079TrpTrp: 0.079 ± 0.084
0.711TrpTyr: 0.711 ± 0.25
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.449TyrAla: 2.449 ± 0.363
1.264TyrCys: 1.264 ± 0.379
2.844TyrAsp: 2.844 ± 0.64
1.343TyrGlu: 1.343 ± 0.365
2.133TyrPhe: 2.133 ± 0.47
2.291TyrGly: 2.291 ± 0.441
0.869TyrHis: 0.869 ± 0.223
1.185TyrIle: 1.185 ± 0.3
1.501TyrLys: 1.501 ± 0.391
3.318TyrLeu: 3.318 ± 0.621
1.422TyrMet: 1.422 ± 0.459
1.106TyrAsn: 1.106 ± 0.302
2.607TyrPro: 2.607 ± 0.446
1.343TyrGln: 1.343 ± 0.386
3.16TyrArg: 3.16 ± 0.567
2.528TyrSer: 2.528 ± 0.513
1.659TyrThr: 1.659 ± 0.397
2.686TyrVal: 2.686 ± 0.489
0.79TyrTrp: 0.79 ± 0.344
0.948TyrTyr: 0.948 ± 0.175
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 46 proteins (12659 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski