Amino acid dipepetide frequency for Parietaria mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.107AlaAla: 6.107 ± 1.64
1.145AlaCys: 1.145 ± 0.917
3.435AlaAsp: 3.435 ± 1.294
1.908AlaGlu: 1.908 ± 0.481
3.817AlaPhe: 3.817 ± 2.333
2.29AlaGly: 2.29 ± 0.732
0.763AlaHis: 0.763 ± 0.288
4.198AlaIle: 4.198 ± 0.866
3.817AlaLys: 3.817 ± 1.153
6.489AlaLeu: 6.489 ± 1.588
2.672AlaMet: 2.672 ± 1.001
2.29AlaAsn: 2.29 ± 1.113
2.29AlaPro: 2.29 ± 1.324
1.527AlaGln: 1.527 ± 0.676
2.29AlaArg: 2.29 ± 0.526
4.58AlaSer: 4.58 ± 1.27
4.962AlaThr: 4.962 ± 0.683
4.962AlaVal: 4.962 ± 2.28
0.763AlaTrp: 0.763 ± 0.514
0.382AlaTyr: 0.382 ± 0.306
0.0AlaXaa: 0.0 ± 0.0
Cys
1.908CysAla: 1.908 ± 0.681
0.763CysCys: 0.763 ± 0.514
1.527CysAsp: 1.527 ± 0.823
1.908CysGlu: 1.908 ± 0.802
1.527CysPhe: 1.527 ± 0.676
1.527CysGly: 1.527 ± 0.823
0.382CysHis: 0.382 ± 0.257
1.145CysIle: 1.145 ± 0.532
0.382CysLys: 0.382 ± 0.257
1.527CysLeu: 1.527 ± 1.034
0.0CysMet: 0.0 ± 0.0
1.145CysAsn: 1.145 ± 0.535
1.145CysPro: 1.145 ± 0.77
0.382CysGln: 0.382 ± 0.257
1.527CysArg: 1.527 ± 0.932
1.908CysSer: 1.908 ± 1.106
0.763CysThr: 0.763 ± 0.288
3.053CysVal: 3.053 ± 0.889
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.489AspAla: 6.489 ± 1.391
1.527AspCys: 1.527 ± 0.612
6.107AspAsp: 6.107 ± 2.16
6.107AspGlu: 6.107 ± 1.696
3.817AspPhe: 3.817 ± 0.953
4.962AspGly: 4.962 ± 1.552
1.145AspHis: 1.145 ± 0.85
4.198AspIle: 4.198 ± 1.138
3.053AspLys: 3.053 ± 1.107
5.725AspLeu: 5.725 ± 1.343
0.763AspMet: 0.763 ± 0.288
0.382AspAsn: 0.382 ± 0.548
2.672AspPro: 2.672 ± 0.89
1.527AspGln: 1.527 ± 0.676
1.908AspArg: 1.908 ± 0.803
5.725AspSer: 5.725 ± 1.665
2.672AspThr: 2.672 ± 0.821
8.397AspVal: 8.397 ± 1.763
0.763AspTrp: 0.763 ± 0.288
2.29AspTyr: 2.29 ± 1.835
0.0AspXaa: 0.0 ± 0.0
Glu
3.053GluAla: 3.053 ± 1.102
1.908GluCys: 1.908 ± 0.712
4.198GluAsp: 4.198 ± 1.246
3.435GluGlu: 3.435 ± 1.082
1.145GluPhe: 1.145 ± 0.451
3.053GluGly: 3.053 ± 1.442
1.908GluHis: 1.908 ± 0.785
4.198GluIle: 4.198 ± 1.265
4.198GluLys: 4.198 ± 2.101
5.344GluLeu: 5.344 ± 1.663
1.145GluMet: 1.145 ± 0.428
3.435GluAsn: 3.435 ± 1.281
0.382GluPro: 0.382 ± 0.673
0.763GluGln: 0.763 ± 0.616
3.435GluArg: 3.435 ± 0.998
4.962GluSer: 4.962 ± 1.102
4.58GluThr: 4.58 ± 1.247
3.817GluVal: 3.817 ± 1.057
1.527GluTrp: 1.527 ± 0.823
1.527GluTyr: 1.527 ± 0.575
0.0GluXaa: 0.0 ± 0.0
Phe
2.672PheAla: 2.672 ± 1.1
0.382PheCys: 0.382 ± 0.257
1.908PheAsp: 1.908 ± 1.12
2.29PheGlu: 2.29 ± 0.79
1.527PhePhe: 1.527 ± 0.823
1.908PheGly: 1.908 ± 1.199
0.382PheHis: 0.382 ± 0.257
2.672PheIle: 2.672 ± 0.693
3.053PheLys: 3.053 ± 0.914
4.962PheLeu: 4.962 ± 1.94
0.0PheMet: 0.0 ± 0.0
4.58PheAsn: 4.58 ± 1.171
2.29PhePro: 2.29 ± 0.5
1.908PheGln: 1.908 ± 0.803
1.908PheArg: 1.908 ± 0.992
2.672PheSer: 2.672 ± 0.411
1.527PheThr: 1.527 ± 0.679
4.58PheVal: 4.58 ± 0.47
0.382PheTrp: 0.382 ± 0.54
1.145PheTyr: 1.145 ± 0.451
0.0PheXaa: 0.0 ± 0.0
Gly
0.763GlyAla: 0.763 ± 0.514
1.908GlyCys: 1.908 ± 0.563
3.817GlyAsp: 3.817 ± 1.132
1.527GlyGlu: 1.527 ± 0.515
3.435GlyPhe: 3.435 ± 0.938
3.053GlyGly: 3.053 ± 1.193
0.763GlyHis: 0.763 ± 0.288
2.672GlyIle: 2.672 ± 0.845
3.817GlyLys: 3.817 ± 0.71
5.344GlyLeu: 5.344 ± 1.139
0.382GlyMet: 0.382 ± 0.548
1.908GlyAsn: 1.908 ± 1.199
1.527GlyPro: 1.527 ± 0.558
1.145GlyGln: 1.145 ± 0.442
3.817GlyArg: 3.817 ± 1.004
5.725GlySer: 5.725 ± 1.545
2.672GlyThr: 2.672 ± 1.253
3.817GlyVal: 3.817 ± 0.217
0.382GlyTrp: 0.382 ± 0.673
0.763GlyTyr: 0.763 ± 0.514
0.0GlyXaa: 0.0 ± 0.0
His
1.908HisAla: 1.908 ± 1.502
0.382HisCys: 0.382 ± 0.257
1.527HisAsp: 1.527 ± 0.823
1.527HisGlu: 1.527 ± 0.575
1.527HisPhe: 1.527 ± 0.476
0.382HisGly: 0.382 ± 0.257
1.908HisHis: 1.908 ± 0.803
1.908HisIle: 1.908 ± 0.808
1.527HisLys: 1.527 ± 0.432
2.29HisLeu: 2.29 ± 0.5
1.527HisMet: 1.527 ± 0.779
0.763HisAsn: 0.763 ± 0.288
0.0HisPro: 0.0 ± 0.0
0.382HisGln: 0.382 ± 0.306
1.527HisArg: 1.527 ± 0.575
3.053HisSer: 3.053 ± 0.507
2.29HisThr: 2.29 ± 0.592
1.527HisVal: 1.527 ± 0.575
0.0HisTrp: 0.0 ± 0.0
0.382HisTyr: 0.382 ± 0.257
0.0HisXaa: 0.0 ± 0.0
Ile
3.817IleAla: 3.817 ± 0.973
0.382IleCys: 0.382 ± 0.306
4.962IleAsp: 4.962 ± 1.483
3.435IleGlu: 3.435 ± 0.93
0.763IlePhe: 0.763 ± 0.659
1.145IleGly: 1.145 ± 0.715
2.29IleHis: 2.29 ± 0.886
0.763IleIle: 0.763 ± 0.288
3.435IleLys: 3.435 ± 1.591
3.435IleLeu: 3.435 ± 0.962
0.0IleMet: 0.0 ± 0.0
2.672IleAsn: 2.672 ± 0.693
8.779IlePro: 8.779 ± 3.271
1.527IleGln: 1.527 ± 0.575
4.198IleArg: 4.198 ± 0.607
4.58IleSer: 4.58 ± 1.58
2.672IleThr: 2.672 ± 1.417
2.29IleVal: 2.29 ± 1.166
0.0IleTrp: 0.0 ± 0.0
0.382IleTyr: 0.382 ± 0.257
0.0IleXaa: 0.0 ± 0.0
Lys
1.908LysAla: 1.908 ± 0.481
1.145LysCys: 1.145 ± 0.9
2.672LysAsp: 2.672 ± 1.411
4.198LysGlu: 4.198 ± 1.063
3.435LysPhe: 3.435 ± 1.485
3.435LysGly: 3.435 ± 1.323
2.29LysHis: 2.29 ± 0.826
3.053LysIle: 3.053 ± 1.229
4.198LysLys: 4.198 ± 1.362
5.725LysLeu: 5.725 ± 2.54
0.763LysMet: 0.763 ± 0.288
4.58LysAsn: 4.58 ± 0.226
3.817LysPro: 3.817 ± 1.161
0.382LysGln: 0.382 ± 0.548
2.672LysArg: 2.672 ± 0.89
4.198LysSer: 4.198 ± 1.574
5.725LysThr: 5.725 ± 1.536
6.87LysVal: 6.87 ± 2.233
0.0LysTrp: 0.0 ± 0.0
1.145LysTyr: 1.145 ± 0.535
0.0LysXaa: 0.0 ± 0.0
Leu
6.107LeuAla: 6.107 ± 0.607
3.817LeuCys: 3.817 ± 1.985
5.344LeuAsp: 5.344 ± 1.237
6.107LeuGlu: 6.107 ± 0.986
3.435LeuPhe: 3.435 ± 1.537
6.107LeuGly: 6.107 ± 1.293
1.527LeuHis: 1.527 ± 0.823
3.435LeuIle: 3.435 ± 0.998
7.634LeuLys: 7.634 ± 0.616
5.725LeuLeu: 5.725 ± 1.295
2.672LeuMet: 2.672 ± 0.874
3.817LeuAsn: 3.817 ± 1.127
4.58LeuPro: 4.58 ± 0.458
3.435LeuGln: 3.435 ± 0.609
4.58LeuArg: 4.58 ± 1.55
8.779LeuSer: 8.779 ± 1.32
6.107LeuThr: 6.107 ± 1.993
6.107LeuVal: 6.107 ± 1.117
0.763LeuTrp: 0.763 ± 0.559
2.672LeuTyr: 2.672 ± 1.496
0.0LeuXaa: 0.0 ± 0.0
Met
1.527MetAla: 1.527 ± 0.679
0.382MetCys: 0.382 ± 0.306
2.29MetAsp: 2.29 ± 0.539
0.763MetGlu: 0.763 ± 0.659
0.763MetPhe: 0.763 ± 0.498
0.763MetGly: 0.763 ± 0.559
0.382MetHis: 0.382 ± 0.306
2.29MetIle: 2.29 ± 0.767
0.382MetLys: 0.382 ± 0.257
1.908MetLeu: 1.908 ± 0.906
1.527MetMet: 1.527 ± 0.515
1.145MetAsn: 1.145 ± 0.451
0.763MetPro: 0.763 ± 0.545
1.145MetGln: 1.145 ± 1.265
1.145MetArg: 1.145 ± 0.572
1.145MetSer: 1.145 ± 0.532
2.672MetThr: 2.672 ± 0.668
1.145MetVal: 1.145 ± 0.535
0.382MetTrp: 0.382 ± 0.548
0.763MetTyr: 0.763 ± 0.784
0.0MetXaa: 0.0 ± 0.0
Asn
2.29AsnAla: 2.29 ± 0.5
0.0AsnCys: 0.0 ± 0.0
3.053AsnAsp: 3.053 ± 0.641
2.672AsnGlu: 2.672 ± 0.821
0.763AsnPhe: 0.763 ± 0.514
2.672AsnGly: 2.672 ± 1.082
1.145AsnHis: 1.145 ± 0.612
2.29AsnIle: 2.29 ± 2.034
1.908AsnLys: 1.908 ± 0.481
5.725AsnLeu: 5.725 ± 0.71
1.908AsnMet: 1.908 ± 1.075
0.763AsnAsn: 0.763 ± 0.517
2.672AsnPro: 2.672 ± 0.941
3.053AsnGln: 3.053 ± 1.696
3.435AsnArg: 3.435 ± 0.766
3.435AsnSer: 3.435 ± 1.183
1.908AsnThr: 1.908 ± 0.567
3.435AsnVal: 3.435 ± 1.351
0.382AsnTrp: 0.382 ± 0.257
0.382AsnTyr: 0.382 ± 0.257
0.0AsnXaa: 0.0 ± 0.0
Pro
2.29ProAla: 2.29 ± 0.767
0.763ProCys: 0.763 ± 0.517
3.817ProAsp: 3.817 ± 1.02
4.198ProGlu: 4.198 ± 1.36
3.053ProPhe: 3.053 ± 0.73
3.053ProGly: 3.053 ± 1.03
1.145ProHis: 1.145 ± 0.535
3.435ProIle: 3.435 ± 1.734
3.435ProLys: 3.435 ± 3.372
4.198ProLeu: 4.198 ± 0.89
0.0ProMet: 0.0 ± 0.0
2.672ProAsn: 2.672 ± 1.372
2.29ProPro: 2.29 ± 1.8
1.145ProGln: 1.145 ± 0.535
2.29ProArg: 2.29 ± 1.397
3.817ProSer: 3.817 ± 1.819
2.672ProThr: 2.672 ± 1.795
5.344ProVal: 5.344 ± 2.482
0.0ProTrp: 0.0 ± 0.0
1.908ProTyr: 1.908 ± 0.712
0.0ProXaa: 0.0 ± 0.0
Gln
0.382GlnAla: 0.382 ± 0.257
0.382GlnCys: 0.382 ± 0.257
1.145GlnAsp: 1.145 ± 0.794
0.763GlnGlu: 0.763 ± 0.612
0.763GlnPhe: 0.763 ± 0.612
1.145GlnGly: 1.145 ± 0.451
1.145GlnHis: 1.145 ± 0.535
1.145GlnIle: 1.145 ± 0.535
1.908GlnLys: 1.908 ± 0.567
3.053GlnLeu: 3.053 ± 0.642
0.763GlnMet: 0.763 ± 0.687
0.0GlnAsn: 0.0 ± 0.0
2.29GlnPro: 2.29 ± 1.319
0.382GlnGln: 0.382 ± 0.54
1.527GlnArg: 1.527 ± 0.612
2.29GlnSer: 2.29 ± 0.701
1.145GlnThr: 1.145 ± 0.612
3.817GlnVal: 3.817 ± 1.357
0.763GlnTrp: 0.763 ± 0.288
1.527GlnTyr: 1.527 ± 0.676
0.0GlnXaa: 0.0 ± 0.0
Arg
3.817ArgAla: 3.817 ± 1.532
1.908ArgCys: 1.908 ± 0.567
3.817ArgAsp: 3.817 ± 1.161
5.344ArgGlu: 5.344 ± 1.543
1.527ArgPhe: 1.527 ± 0.575
1.145ArgGly: 1.145 ± 0.794
1.145ArgHis: 1.145 ± 0.572
2.29ArgIle: 2.29 ± 1.286
3.053ArgLys: 3.053 ± 0.801
6.489ArgLeu: 6.489 ± 1.909
1.527ArgMet: 1.527 ± 0.756
3.817ArgAsn: 3.817 ± 1.035
1.527ArgPro: 1.527 ± 0.944
1.145ArgGln: 1.145 ± 0.442
3.435ArgArg: 3.435 ± 0.693
6.87ArgSer: 6.87 ± 2.406
3.817ArgThr: 3.817 ± 0.653
1.908ArgVal: 1.908 ± 0.482
1.145ArgTrp: 1.145 ± 0.451
2.29ArgTyr: 2.29 ± 1.165
0.0ArgXaa: 0.0 ± 0.0
Ser
3.435SerAla: 3.435 ± 0.405
3.435SerCys: 3.435 ± 1.044
8.015SerAsp: 8.015 ± 1.364
2.672SerGlu: 2.672 ± 0.396
3.435SerPhe: 3.435 ± 1.183
4.962SerGly: 4.962 ± 0.879
2.29SerHis: 2.29 ± 0.863
3.053SerIle: 3.053 ± 1.03
4.962SerLys: 4.962 ± 1.821
10.305SerLeu: 10.305 ± 1.008
1.145SerMet: 1.145 ± 0.77
3.435SerAsn: 3.435 ± 0.957
1.908SerPro: 1.908 ± 0.679
3.053SerGln: 3.053 ± 0.894
6.489SerArg: 6.489 ± 1.154
7.634SerSer: 7.634 ± 1.16
3.053SerThr: 3.053 ± 2.474
6.87SerVal: 6.87 ± 1.395
0.763SerTrp: 0.763 ± 0.288
3.053SerTyr: 3.053 ± 1.352
0.0SerXaa: 0.0 ± 0.0
Thr
3.435ThrAla: 3.435 ± 1.748
0.763ThrCys: 0.763 ± 0.288
3.817ThrAsp: 3.817 ± 1.236
2.672ThrGlu: 2.672 ± 0.663
1.908ThrPhe: 1.908 ± 0.877
2.29ThrGly: 2.29 ± 1.074
3.435ThrHis: 3.435 ± 0.699
3.435ThrIle: 3.435 ± 1.323
3.053ThrLys: 3.053 ± 1.361
6.107ThrLeu: 6.107 ± 1.792
3.435ThrMet: 3.435 ± 1.586
2.672ThrAsn: 2.672 ± 1.105
2.29ThrPro: 2.29 ± 0.951
1.145ThrGln: 1.145 ± 0.532
3.053ThrArg: 3.053 ± 0.475
2.29ThrSer: 2.29 ± 0.885
4.962ThrThr: 4.962 ± 1.382
3.435ThrVal: 3.435 ± 1.276
1.145ThrTrp: 1.145 ± 0.428
2.672ThrTyr: 2.672 ± 0.988
0.0ThrXaa: 0.0 ± 0.0
Val
6.87ValAla: 6.87 ± 1.435
0.763ValCys: 0.763 ± 0.514
7.252ValAsp: 7.252 ± 0.701
4.962ValGlu: 4.962 ± 1.028
3.435ValPhe: 3.435 ± 0.949
3.435ValGly: 3.435 ± 0.411
1.145ValHis: 1.145 ± 0.532
3.053ValIle: 3.053 ± 0.751
5.344ValLys: 5.344 ± 1.583
6.107ValLeu: 6.107 ± 1.289
1.145ValMet: 1.145 ± 0.532
3.053ValAsn: 3.053 ± 1.356
8.779ValPro: 8.779 ± 1.603
1.527ValGln: 1.527 ± 0.575
5.725ValArg: 5.725 ± 0.811
7.252ValSer: 7.252 ± 1.608
2.29ValThr: 2.29 ± 0.693
5.725ValVal: 5.725 ± 1.834
1.145ValTrp: 1.145 ± 1.025
2.29ValTyr: 2.29 ± 0.701
0.0ValXaa: 0.0 ± 0.0
Trp
0.382TrpAla: 0.382 ± 0.257
0.382TrpCys: 0.382 ± 0.54
0.382TrpAsp: 0.382 ± 0.257
0.382TrpGlu: 0.382 ± 0.257
1.527TrpPhe: 1.527 ± 0.476
0.763TrpGly: 0.763 ± 0.612
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.145TrpLys: 1.145 ± 0.451
0.382TrpLeu: 0.382 ± 0.257
0.0TrpMet: 0.0 ± 0.0
0.382TrpAsn: 0.382 ± 0.673
0.382TrpPro: 0.382 ± 0.548
0.0TrpGln: 0.0 ± 0.0
0.382TrpArg: 0.382 ± 0.257
0.763TrpSer: 0.763 ± 0.612
0.763TrpThr: 0.763 ± 0.498
1.527TrpVal: 1.527 ± 0.932
0.0TrpTrp: 0.0 ± 0.0
0.763TrpTyr: 0.763 ± 0.498
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.527TyrAla: 1.527 ± 1.027
0.382TyrCys: 0.382 ± 0.257
1.145TyrAsp: 1.145 ± 0.535
1.145TyrGlu: 1.145 ± 0.687
1.145TyrPhe: 1.145 ± 0.535
1.145TyrGly: 1.145 ± 0.428
1.145TyrHis: 1.145 ± 0.917
2.29TyrIle: 2.29 ± 0.767
1.908TyrLys: 1.908 ± 0.623
1.908TyrLeu: 1.908 ± 0.785
1.527TyrMet: 1.527 ± 0.575
0.382TyrAsn: 0.382 ± 0.257
1.145TyrPro: 1.145 ± 0.428
1.145TyrGln: 1.145 ± 0.715
2.672TyrArg: 2.672 ± 0.754
2.29TyrSer: 2.29 ± 0.903
0.763TyrThr: 0.763 ± 0.288
2.672TyrVal: 2.672 ± 1.12
0.0TyrTrp: 0.0 ± 0.0
0.763TyrTyr: 0.763 ± 0.288
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2621 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski