Amino acid dipepetide frequency for Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus) (Graphiocladiella clavigera)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.024AlaAla: 15.024 ± 0.112
1.1AlaCys: 1.1 ± 0.02
5.899AlaAsp: 5.899 ± 0.043
6.057AlaGlu: 6.057 ± 0.055
3.263AlaPhe: 3.263 ± 0.032
7.597AlaGly: 7.597 ± 0.054
2.011AlaHis: 2.011 ± 0.026
4.1AlaIle: 4.1 ± 0.033
3.937AlaLys: 3.937 ± 0.039
8.57AlaLeu: 8.57 ± 0.063
2.304AlaMet: 2.304 ± 0.023
2.96AlaAsn: 2.96 ± 0.029
5.105AlaPro: 5.105 ± 0.053
3.666AlaGln: 3.666 ± 0.038
5.984AlaArg: 5.984 ± 0.039
8.806AlaSer: 8.806 ± 0.065
6.735AlaThr: 6.735 ± 0.051
7.569AlaVal: 7.569 ± 0.056
1.255AlaTrp: 1.255 ± 0.018
2.306AlaTyr: 2.306 ± 0.023
0.0AlaXaa: 0.0 ± 0.0
Cys
0.967CysAla: 0.967 ± 0.017
0.235CysCys: 0.235 ± 0.008
0.634CysAsp: 0.634 ± 0.013
0.515CysGlu: 0.515 ± 0.012
0.492CysPhe: 0.492 ± 0.01
0.916CysGly: 0.916 ± 0.017
0.309CysHis: 0.309 ± 0.008
0.619CysIle: 0.619 ± 0.013
0.383CysLys: 0.383 ± 0.01
1.196CysLeu: 1.196 ± 0.02
0.253CysMet: 0.253 ± 0.008
0.354CysAsn: 0.354 ± 0.009
0.614CysPro: 0.614 ± 0.013
0.405CysGln: 0.405 ± 0.009
0.826CysArg: 0.826 ± 0.015
0.883CysSer: 0.883 ± 0.015
0.645CysThr: 0.645 ± 0.014
0.8CysVal: 0.8 ± 0.016
0.185CysTrp: 0.185 ± 0.007
0.331CysTyr: 0.331 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
5.56AspAla: 5.56 ± 0.039
0.624AspCys: 0.624 ± 0.013
5.199AspAsp: 5.199 ± 0.064
4.75AspGlu: 4.75 ± 0.051
2.063AspPhe: 2.063 ± 0.023
5.122AspGly: 5.122 ± 0.044
1.182AspHis: 1.182 ± 0.018
2.593AspIle: 2.593 ± 0.028
2.15AspLys: 2.15 ± 0.026
4.948AspLeu: 4.948 ± 0.034
1.349AspMet: 1.349 ± 0.016
1.826AspAsn: 1.826 ± 0.019
2.892AspPro: 2.892 ± 0.027
1.684AspGln: 1.684 ± 0.02
3.576AspArg: 3.576 ± 0.037
4.215AspSer: 4.215 ± 0.037
2.87AspThr: 2.87 ± 0.026
4.27AspVal: 4.27 ± 0.035
0.837AspTrp: 0.837 ± 0.015
1.502AspTyr: 1.502 ± 0.02
0.0AspXaa: 0.0 ± 0.0
Glu
6.342GluAla: 6.342 ± 0.058
0.505GluCys: 0.505 ± 0.012
4.101GluAsp: 4.101 ± 0.046
4.766GluGlu: 4.766 ± 0.059
1.562GluPhe: 1.562 ± 0.021
3.357GluGly: 3.357 ± 0.031
1.286GluHis: 1.286 ± 0.017
2.376GluIle: 2.376 ± 0.023
2.967GluLys: 2.967 ± 0.039
4.97GluLeu: 4.97 ± 0.039
1.379GluMet: 1.379 ± 0.018
1.804GluAsn: 1.804 ± 0.024
2.621GluPro: 2.621 ± 0.034
2.48GluGln: 2.48 ± 0.03
4.04GluArg: 4.04 ± 0.041
3.744GluSer: 3.744 ± 0.035
3.499GluThr: 3.499 ± 0.033
3.258GluVal: 3.258 ± 0.036
0.707GluTrp: 0.707 ± 0.014
1.392GluTyr: 1.392 ± 0.019
0.0GluXaa: 0.0 ± 0.0
Phe
3.183PheAla: 3.183 ± 0.03
0.537PheCys: 0.537 ± 0.012
2.155PheAsp: 2.155 ± 0.025
1.839PheGlu: 1.839 ± 0.021
1.492PhePhe: 1.492 ± 0.025
2.83PheGly: 2.83 ± 0.032
0.827PheHis: 0.827 ± 0.014
1.327PheIle: 1.327 ± 0.019
1.058PheLys: 1.058 ± 0.018
3.196PheLeu: 3.196 ± 0.035
0.664PheMet: 0.664 ± 0.013
1.091PheAsn: 1.091 ± 0.017
1.77PhePro: 1.77 ± 0.019
1.222PheGln: 1.222 ± 0.017
2.095PheArg: 2.095 ± 0.022
2.889PheSer: 2.889 ± 0.028
1.764PheThr: 1.764 ± 0.022
2.565PheVal: 2.565 ± 0.03
0.579PheTrp: 0.579 ± 0.012
0.993PheTyr: 0.993 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
6.278GlyAla: 6.278 ± 0.048
0.898GlyCys: 0.898 ± 0.015
4.017GlyAsp: 4.017 ± 0.032
3.615GlyGlu: 3.615 ± 0.035
2.7GlyPhe: 2.7 ± 0.032
7.503GlyGly: 7.503 ± 0.085
1.982GlyHis: 1.982 ± 0.026
3.161GlyIle: 3.161 ± 0.032
2.872GlyLys: 2.872 ± 0.03
6.532GlyLeu: 6.532 ± 0.05
1.575GlyMet: 1.575 ± 0.02
2.519GlyAsn: 2.519 ± 0.028
3.685GlyPro: 3.685 ± 0.033
2.769GlyGln: 2.769 ± 0.03
5.211GlyArg: 5.211 ± 0.04
6.965GlySer: 6.965 ± 0.062
4.342GlyThr: 4.342 ± 0.041
4.449GlyVal: 4.449 ± 0.032
1.113GlyTrp: 1.113 ± 0.016
1.951GlyTyr: 1.951 ± 0.024
0.0GlyXaa: 0.0 ± 0.0
His
2.014HisAla: 2.014 ± 0.022
0.3HisCys: 0.3 ± 0.008
1.383HisAsp: 1.383 ± 0.02
1.241HisGlu: 1.241 ± 0.016
0.824HisPhe: 0.824 ± 0.015
1.947HisGly: 1.947 ± 0.021
0.935HisHis: 0.935 ± 0.019
1.079HisIle: 1.079 ± 0.018
0.79HisLys: 0.79 ± 0.014
2.106HisLeu: 2.106 ± 0.022
0.53HisMet: 0.53 ± 0.01
0.8HisAsn: 0.8 ± 0.014
1.486HisPro: 1.486 ± 0.02
1.023HisGln: 1.023 ± 0.018
1.68HisArg: 1.68 ± 0.021
1.734HisSer: 1.734 ± 0.019
1.206HisThr: 1.206 ± 0.019
1.599HisVal: 1.599 ± 0.019
0.316HisTrp: 0.316 ± 0.008
0.671HisTyr: 0.671 ± 0.013
0.0HisXaa: 0.0 ± 0.0
Ile
3.888IleAla: 3.888 ± 0.032
0.626IleCys: 0.626 ± 0.013
2.579IleAsp: 2.579 ± 0.026
2.329IleGlu: 2.329 ± 0.028
1.558IlePhe: 1.558 ± 0.023
2.977IleGly: 2.977 ± 0.031
0.941IleHis: 0.941 ± 0.014
1.768IleIle: 1.768 ± 0.026
1.556IleLys: 1.556 ± 0.02
3.68IleLeu: 3.68 ± 0.036
0.874IleMet: 0.874 ± 0.015
1.396IleAsn: 1.396 ± 0.018
2.385IlePro: 2.385 ± 0.025
1.479IleGln: 1.479 ± 0.018
2.551IleArg: 2.551 ± 0.025
3.152IleSer: 3.152 ± 0.032
2.275IleThr: 2.275 ± 0.023
3.092IleVal: 3.092 ± 0.031
0.587IleTrp: 0.587 ± 0.012
1.11IleTyr: 1.11 ± 0.016
0.0IleXaa: 0.0 ± 0.0
Lys
4.07LysAla: 4.07 ± 0.036
0.358LysCys: 0.358 ± 0.009
2.208LysAsp: 2.208 ± 0.025
2.553LysGlu: 2.553 ± 0.035
1.033LysPhe: 1.033 ± 0.018
2.363LysGly: 2.363 ± 0.03
0.902LysHis: 0.902 ± 0.014
1.654LysIle: 1.654 ± 0.021
2.724LysLys: 2.724 ± 0.049
3.347LysLeu: 3.347 ± 0.034
0.882LysMet: 0.882 ± 0.014
1.338LysAsn: 1.338 ± 0.019
2.135LysPro: 2.135 ± 0.024
1.592LysGln: 1.592 ± 0.019
2.944LysArg: 2.944 ± 0.031
2.662LysSer: 2.662 ± 0.03
2.697LysThr: 2.697 ± 0.028
2.218LysVal: 2.218 ± 0.025
0.481LysTrp: 0.481 ± 0.011
1.024LysTyr: 1.024 ± 0.016
0.0LysXaa: 0.0 ± 0.0
Leu
9.457LeuAla: 9.457 ± 0.064
1.206LeuCys: 1.206 ± 0.018
5.315LeuAsp: 5.315 ± 0.042
4.973LeuGlu: 4.973 ± 0.046
3.205LeuPhe: 3.205 ± 0.036
6.049LeuGly: 6.049 ± 0.043
2.289LeuHis: 2.289 ± 0.024
3.086LeuIle: 3.086 ± 0.034
3.205LeuLys: 3.205 ± 0.034
8.816LeuLeu: 8.816 ± 0.077
1.705LeuMet: 1.705 ± 0.022
2.511LeuAsn: 2.511 ± 0.028
5.684LeuPro: 5.684 ± 0.037
4.057LeuGln: 4.057 ± 0.035
6.311LeuArg: 6.311 ± 0.044
7.167LeuSer: 7.167 ± 0.05
4.614LeuThr: 4.614 ± 0.033
6.0LeuVal: 6.0 ± 0.054
1.187LeuTrp: 1.187 ± 0.019
2.224LeuTyr: 2.224 ± 0.024
0.0LeuXaa: 0.0 ± 0.0
Met
2.745MetAla: 2.745 ± 0.027
0.234MetCys: 0.234 ± 0.008
1.244MetAsp: 1.244 ± 0.017
1.144MetGlu: 1.144 ± 0.018
0.662MetPhe: 0.662 ± 0.013
1.511MetGly: 1.511 ± 0.02
0.504MetHis: 0.504 ± 0.012
0.785MetIle: 0.785 ± 0.014
0.724MetLys: 0.724 ± 0.012
1.936MetLeu: 1.936 ± 0.021
0.55MetMet: 0.55 ± 0.013
0.601MetAsn: 0.601 ± 0.014
1.342MetPro: 1.342 ± 0.018
0.915MetGln: 0.915 ± 0.015
1.411MetArg: 1.411 ± 0.019
1.818MetSer: 1.818 ± 0.019
1.323MetThr: 1.323 ± 0.016
1.303MetVal: 1.303 ± 0.02
0.238MetTrp: 0.238 ± 0.008
0.488MetTyr: 0.488 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
2.873AsnAla: 2.873 ± 0.028
0.373AsnCys: 0.373 ± 0.009
1.725AsnAsp: 1.725 ± 0.021
1.645AsnGlu: 1.645 ± 0.021
1.092AsnPhe: 1.092 ± 0.014
3.044AsnGly: 3.044 ± 0.038
0.686AsnHis: 0.686 ± 0.011
1.582AsnIle: 1.582 ± 0.02
1.216AsnLys: 1.216 ± 0.016
2.561AsnLeu: 2.561 ± 0.026
0.783AsnMet: 0.783 ± 0.014
1.286AsnAsn: 1.286 ± 0.022
1.791AsnPro: 1.791 ± 0.024
1.019AsnGln: 1.019 ± 0.017
1.802AsnArg: 1.802 ± 0.022
2.477AsnSer: 2.477 ± 0.029
1.944AsnThr: 1.944 ± 0.018
2.101AsnVal: 2.101 ± 0.023
0.431AsnTrp: 0.431 ± 0.01
0.869AsnTyr: 0.869 ± 0.015
0.0AsnXaa: 0.0 ± 0.0
Pro
6.274ProAla: 6.274 ± 0.055
0.463ProCys: 0.463 ± 0.012
3.193ProAsp: 3.193 ± 0.03
3.216ProGlu: 3.216 ± 0.031
1.919ProPhe: 1.919 ± 0.018
4.102ProGly: 4.102 ± 0.034
1.274ProHis: 1.274 ± 0.018
2.176ProIle: 2.176 ± 0.022
2.028ProLys: 2.028 ± 0.03
4.93ProLeu: 4.93 ± 0.035
1.115ProMet: 1.115 ± 0.018
1.687ProAsn: 1.687 ± 0.021
5.247ProPro: 5.247 ± 0.076
2.305ProGln: 2.305 ± 0.024
3.47ProArg: 3.47 ± 0.032
5.713ProSer: 5.713 ± 0.056
3.936ProThr: 3.936 ± 0.037
3.902ProVal: 3.902 ± 0.037
0.705ProTrp: 0.705 ± 0.012
1.38ProTyr: 1.38 ± 0.021
0.0ProXaa: 0.0 ± 0.0
Gln
3.928GlnAla: 3.928 ± 0.041
0.391GlnCys: 0.391 ± 0.01
1.937GlnAsp: 1.937 ± 0.022
2.05GlnGlu: 2.05 ± 0.027
1.142GlnPhe: 1.142 ± 0.017
2.171GlnGly: 2.171 ± 0.022
1.196GlnHis: 1.196 ± 0.022
1.548GlnIle: 1.548 ± 0.02
1.712GlnLys: 1.712 ± 0.025
3.799GlnLeu: 3.799 ± 0.032
0.94GlnMet: 0.94 ± 0.015
1.268GlnAsn: 1.268 ± 0.02
2.745GlnPro: 2.745 ± 0.029
3.513GlnGln: 3.513 ± 0.076
2.927GlnArg: 2.927 ± 0.029
2.841GlnSer: 2.841 ± 0.029
2.477GlnThr: 2.477 ± 0.024
2.115GlnVal: 2.115 ± 0.024
0.514GlnTrp: 0.514 ± 0.01
1.016GlnTyr: 1.016 ± 0.015
0.0GlnXaa: 0.0 ± 0.0
Arg
5.723ArgAla: 5.723 ± 0.039
0.777ArgCys: 0.777 ± 0.015
3.672ArgAsp: 3.672 ± 0.039
3.826ArgGlu: 3.826 ± 0.041
2.193ArgPhe: 2.193 ± 0.024
4.14ArgGly: 4.14 ± 0.035
1.825ArgHis: 1.825 ± 0.023
2.739ArgIle: 2.739 ± 0.022
3.026ArgLys: 3.026 ± 0.033
6.447ArgLeu: 6.447 ± 0.043
1.399ArgMet: 1.399 ± 0.018
2.095ArgAsn: 2.095 ± 0.024
4.178ArgPro: 4.178 ± 0.038
3.183ArgGln: 3.183 ± 0.033
6.362ArgArg: 6.362 ± 0.055
5.068ArgSer: 5.068 ± 0.042
3.658ArgThr: 3.658 ± 0.032
3.741ArgVal: 3.741 ± 0.028
1.006ArgTrp: 1.006 ± 0.016
1.631ArgTyr: 1.631 ± 0.02
0.0ArgXaa: 0.0 ± 0.0
Ser
8.137SerAla: 8.137 ± 0.054
0.841SerCys: 0.841 ± 0.016
4.262SerAsp: 4.262 ± 0.035
3.703SerGlu: 3.703 ± 0.031
2.882SerPhe: 2.882 ± 0.027
6.518SerGly: 6.518 ± 0.054
1.813SerHis: 1.813 ± 0.024
3.376SerIle: 3.376 ± 0.031
2.901SerLys: 2.901 ± 0.033
7.061SerLeu: 7.061 ± 0.047
1.709SerMet: 1.709 ± 0.021
2.584SerAsn: 2.584 ± 0.026
5.434SerPro: 5.434 ± 0.057
2.971SerGln: 2.971 ± 0.034
5.401SerArg: 5.401 ± 0.042
9.957SerSer: 9.957 ± 0.119
5.66SerThr: 5.66 ± 0.06
5.021SerVal: 5.021 ± 0.036
1.053SerTrp: 1.053 ± 0.015
1.899SerTyr: 1.899 ± 0.025
0.0SerXaa: 0.0 ± 0.0
Thr
7.354ThrAla: 7.354 ± 0.053
0.673ThrCys: 0.673 ± 0.013
3.094ThrAsp: 3.094 ± 0.029
2.999ThrGlu: 2.999 ± 0.025
1.99ThrPhe: 1.99 ± 0.025
4.568ThrGly: 4.568 ± 0.038
1.143ThrHis: 1.143 ± 0.016
2.606ThrIle: 2.606 ± 0.025
2.2ThrLys: 2.2 ± 0.03
4.908ThrLeu: 4.908 ± 0.036
1.254ThrMet: 1.254 ± 0.016
1.843ThrAsn: 1.843 ± 0.027
4.108ThrPro: 4.108 ± 0.035
1.869ThrGln: 1.869 ± 0.022
3.288ThrArg: 3.288 ± 0.027
5.344ThrSer: 5.344 ± 0.051
4.916ThrThr: 4.916 ± 0.062
4.156ThrVal: 4.156 ± 0.038
0.764ThrTrp: 0.764 ± 0.012
1.452ThrTyr: 1.452 ± 0.022
0.0ThrXaa: 0.0 ± 0.0
Val
6.973ValAla: 6.973 ± 0.051
0.867ValCys: 0.867 ± 0.013
4.123ValAsp: 4.123 ± 0.031
3.813ValGlu: 3.813 ± 0.049
2.509ValPhe: 2.509 ± 0.027
4.444ValGly: 4.444 ± 0.037
1.542ValHis: 1.542 ± 0.02
2.557ValIle: 2.557 ± 0.028
2.287ValLys: 2.287 ± 0.026
6.374ValLeu: 6.374 ± 0.046
1.302ValMet: 1.302 ± 0.018
1.903ValAsn: 1.903 ± 0.021
3.928ValPro: 3.928 ± 0.032
2.558ValGln: 2.558 ± 0.025
4.219ValArg: 4.219 ± 0.034
4.992ValSer: 4.992 ± 0.035
3.643ValThr: 3.643 ± 0.036
5.127ValVal: 5.127 ± 0.044
0.91ValTrp: 0.91 ± 0.015
1.701ValTyr: 1.701 ± 0.017
0.0ValXaa: 0.0 ± 0.0
Trp
1.212TrpAla: 1.212 ± 0.02
0.184TrpCys: 0.184 ± 0.007
0.848TrpAsp: 0.848 ± 0.015
0.719TrpGlu: 0.719 ± 0.013
0.455TrpPhe: 0.455 ± 0.01
0.826TrpGly: 0.826 ± 0.016
0.352TrpHis: 0.352 ± 0.01
0.596TrpIle: 0.596 ± 0.011
0.609TrpLys: 0.609 ± 0.011
1.329TrpLeu: 1.329 ± 0.019
0.352TrpMet: 0.352 ± 0.009
0.504TrpAsn: 0.504 ± 0.012
0.648TrpPro: 0.648 ± 0.013
0.587TrpGln: 0.587 ± 0.011
0.973TrpArg: 0.973 ± 0.017
0.949TrpSer: 0.949 ± 0.014
0.949TrpThr: 0.949 ± 0.016
0.799TrpVal: 0.799 ± 0.014
0.256TrpTrp: 0.256 ± 0.008
0.37TrpTyr: 0.37 ± 0.01
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.245TyrAla: 2.245 ± 0.022
0.371TyrCys: 0.371 ± 0.011
1.624TyrAsp: 1.624 ± 0.019
1.402TyrGlu: 1.402 ± 0.02
1.04TyrPhe: 1.04 ± 0.015
2.154TyrGly: 2.154 ± 0.022
0.664TyrHis: 0.664 ± 0.013
1.075TyrIle: 1.075 ± 0.016
0.839TyrLys: 0.839 ± 0.016
2.359TyrLeu: 2.359 ± 0.03
0.56TyrMet: 0.56 ± 0.009
0.929TyrAsn: 0.929 ± 0.014
1.239TyrPro: 1.239 ± 0.021
0.933TyrGln: 0.933 ± 0.017
1.617TyrArg: 1.617 ± 0.02
1.807TyrSer: 1.807 ± 0.019
1.374TyrThr: 1.374 ± 0.02
1.686TyrVal: 1.686 ± 0.018
0.393TyrTrp: 0.393 ± 0.01
0.846TyrTyr: 0.846 ± 0.015
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8311 proteins (4531634 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski