Amino acid dipepetide frequency for Beet cryptic virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.64AlaAla: 4.64 ± 1.534
0.0AlaCys: 0.0 ± 0.0
4.64AlaAsp: 4.64 ± 2.311
2.32AlaGlu: 2.32 ± 1.029
7.734AlaPhe: 7.734 ± 3.697
1.547AlaGly: 1.547 ± 0.584
0.773AlaHis: 0.773 ± 0.593
4.64AlaIle: 4.64 ± 2.48
4.64AlaLys: 4.64 ± 0.887
5.414AlaLeu: 5.414 ± 0.842
1.547AlaMet: 1.547 ± 0.664
5.414AlaAsn: 5.414 ± 1.214
6.187AlaPro: 6.187 ± 0.443
1.547AlaGln: 1.547 ± 0.632
3.094AlaArg: 3.094 ± 2.666
3.867AlaSer: 3.867 ± 1.739
6.961AlaThr: 6.961 ± 1.354
1.547AlaVal: 1.547 ± 0.598
3.094AlaTrp: 3.094 ± 1.264
6.961AlaTyr: 6.961 ± 3.566
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.773CysAsp: 0.773 ± 0.666
0.0CysGlu: 0.0 ± 0.0
0.773CysPhe: 0.773 ± 0.541
0.773CysGly: 0.773 ± 0.593
0.0CysHis: 0.0 ± 0.0
0.773CysIle: 0.773 ± 0.593
0.0CysLys: 0.0 ± 0.0
0.773CysLeu: 0.773 ± 0.541
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.773CysPro: 0.773 ± 0.666
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.547CysThr: 1.547 ± 0.632
1.547CysVal: 1.547 ± 0.598
0.0CysTrp: 0.0 ± 0.0
2.32CysTyr: 2.32 ± 1.155
0.0CysXaa: 0.0 ± 0.0
Asp
6.961AspAla: 6.961 ± 2.118
0.0AspCys: 0.0 ± 0.0
3.094AspAsp: 3.094 ± 1.393
3.867AspGlu: 3.867 ± 0.725
1.547AspPhe: 1.547 ± 1.187
3.094AspGly: 3.094 ± 0.605
0.773AspHis: 0.773 ± 0.593
2.32AspIle: 2.32 ± 0.926
1.547AspLys: 1.547 ± 0.632
7.734AspLeu: 7.734 ± 0.303
1.547AspMet: 1.547 ± 0.598
0.773AspAsn: 0.773 ± 0.666
4.64AspPro: 4.64 ± 0.199
0.0AspGln: 0.0 ± 0.0
3.094AspArg: 3.094 ± 1.264
3.094AspSer: 3.094 ± 1.169
3.867AspThr: 3.867 ± 0.509
3.094AspVal: 3.094 ± 0.454
1.547AspTrp: 1.547 ± 0.584
3.867AspTyr: 3.867 ± 2.426
0.0AspXaa: 0.0 ± 0.0
Glu
5.414GluAla: 5.414 ± 0.633
0.773GluCys: 0.773 ± 0.541
6.961GluAsp: 6.961 ± 1.798
3.094GluGlu: 3.094 ± 1.169
0.0GluPhe: 0.0 ± 0.0
1.547GluGly: 1.547 ± 1.082
1.547GluHis: 1.547 ± 1.082
3.867GluIle: 3.867 ± 0.993
0.773GluLys: 0.773 ± 0.541
7.734GluLeu: 7.734 ± 0.674
1.547GluMet: 1.547 ± 1.015
3.094GluAsn: 3.094 ± 0.454
2.32GluPro: 2.32 ± 1.155
3.094GluGln: 3.094 ± 0.454
1.547GluArg: 1.547 ± 0.632
4.64GluSer: 4.64 ± 1.008
3.094GluThr: 3.094 ± 1.197
0.773GluVal: 0.773 ± 0.541
0.773GluTrp: 0.773 ± 0.593
3.867GluTyr: 3.867 ± 1.491
0.0GluXaa: 0.0 ± 0.0
Phe
1.547PheAla: 1.547 ± 1.082
0.0PheCys: 0.0 ± 0.0
2.32PheAsp: 2.32 ± 0.957
3.094PheGlu: 3.094 ± 1.169
1.547PhePhe: 1.547 ± 0.584
1.547PheGly: 1.547 ± 0.632
1.547PheHis: 1.547 ± 1.082
3.094PheIle: 3.094 ± 0.454
2.32PheLys: 2.32 ± 1.029
3.094PheLeu: 3.094 ± 0.605
0.773PheMet: 0.773 ± 0.593
2.32PheAsn: 2.32 ± 0.957
3.867PhePro: 3.867 ± 1.418
0.773PheGln: 0.773 ± 0.666
4.64PheArg: 4.64 ± 1.254
0.773PheSer: 0.773 ± 0.541
6.961PheThr: 6.961 ± 0.979
0.773PheVal: 0.773 ± 0.541
1.547PheTrp: 1.547 ± 0.632
0.773PheTyr: 0.773 ± 0.666
0.0PheXaa: 0.0 ± 0.0
Gly
4.64GlyAla: 4.64 ± 2.311
0.773GlyCys: 0.773 ± 0.593
3.094GlyAsp: 3.094 ± 1.441
1.547GlyGlu: 1.547 ± 1.082
0.0GlyPhe: 0.0 ± 0.0
0.773GlyGly: 0.773 ± 0.541
0.0GlyHis: 0.0 ± 0.0
4.64GlyIle: 4.64 ± 0.887
2.32GlyLys: 2.32 ± 0.926
2.32GlyLeu: 2.32 ± 0.1
0.0GlyMet: 0.0 ± 0.0
3.094GlyAsn: 3.094 ± 1.556
3.094GlyPro: 3.094 ± 1.169
3.094GlyGln: 3.094 ± 1.169
3.867GlyArg: 3.867 ± 0.509
4.64GlySer: 4.64 ± 0.887
3.867GlyThr: 3.867 ± 1.195
1.547GlyVal: 1.547 ± 1.082
2.32GlyTrp: 2.32 ± 1.145
1.547GlyTyr: 1.547 ± 1.082
0.0GlyXaa: 0.0 ± 0.0
His
3.094HisAla: 3.094 ± 0.605
0.0HisCys: 0.0 ± 0.0
0.773HisAsp: 0.773 ± 0.666
0.773HisGlu: 0.773 ± 0.541
1.547HisPhe: 1.547 ± 0.632
0.773HisGly: 0.773 ± 0.541
0.0HisHis: 0.0 ± 0.0
2.32HisIle: 2.32 ± 1.145
2.32HisLys: 2.32 ± 0.926
3.094HisLeu: 3.094 ± 0.605
0.773HisMet: 0.773 ± 0.541
0.773HisAsn: 0.773 ± 0.593
1.547HisPro: 1.547 ± 0.598
2.32HisGln: 2.32 ± 1.78
0.773HisArg: 0.773 ± 0.666
1.547HisSer: 1.547 ± 0.584
0.0HisThr: 0.0 ± 0.0
2.32HisVal: 2.32 ± 0.957
0.773HisTrp: 0.773 ± 0.593
2.32HisTyr: 2.32 ± 0.1
0.0HisXaa: 0.0 ± 0.0
Ile
2.32IleAla: 2.32 ± 0.926
0.0IleCys: 0.0 ± 0.0
2.32IleAsp: 2.32 ± 0.957
3.094IleGlu: 3.094 ± 0.454
0.0IlePhe: 0.0 ± 0.0
3.867IleGly: 3.867 ± 0.993
6.187IleHis: 6.187 ± 0.82
3.867IleIle: 3.867 ± 0.619
3.094IleLys: 3.094 ± 1.393
6.961IleLeu: 6.961 ± 0.299
0.773IleMet: 0.773 ± 0.541
3.094IleAsn: 3.094 ± 1.393
5.414IlePro: 5.414 ± 1.574
1.547IleGln: 1.547 ± 1.333
3.094IleArg: 3.094 ± 1.598
5.414IleSer: 5.414 ± 0.373
6.961IleThr: 6.961 ± 1.268
2.32IleVal: 2.32 ± 1.155
1.547IleTrp: 1.547 ± 0.598
2.32IleTyr: 2.32 ± 1.145
0.0IleXaa: 0.0 ± 0.0
Lys
5.414LysAla: 5.414 ± 1.091
0.0LysCys: 0.0 ± 0.0
3.094LysAsp: 3.094 ± 1.169
2.32LysGlu: 2.32 ± 0.926
1.547LysPhe: 1.547 ± 0.584
3.094LysGly: 3.094 ± 1.393
0.773LysHis: 0.773 ± 0.593
3.094LysIle: 3.094 ± 0.454
3.094LysLys: 3.094 ± 0.454
2.32LysLeu: 2.32 ± 0.1
0.773LysMet: 0.773 ± 0.541
1.547LysAsn: 1.547 ± 0.632
2.32LysPro: 2.32 ± 1.145
0.773LysGln: 0.773 ± 0.593
2.32LysArg: 2.32 ± 0.1
3.094LysSer: 3.094 ± 1.197
2.32LysThr: 2.32 ± 1.145
3.867LysVal: 3.867 ± 1.9
0.0LysTrp: 0.0 ± 0.0
1.547LysTyr: 1.547 ± 0.584
0.0LysXaa: 0.0 ± 0.0
Leu
5.414LeuAla: 5.414 ± 1.873
0.0LeuCys: 0.0 ± 0.0
6.187LeuAsp: 6.187 ± 1.838
4.64LeuGlu: 4.64 ± 2.422
3.094LeuPhe: 3.094 ± 0.605
6.187LeuGly: 6.187 ± 2.155
2.32LeuHis: 2.32 ± 0.926
7.734LeuIle: 7.734 ± 1.962
3.094LeuLys: 3.094 ± 1.197
6.961LeuLeu: 6.961 ± 0.857
0.773LeuMet: 0.773 ± 0.666
6.961LeuAsn: 6.961 ± 1.798
1.547LeuPro: 1.547 ± 1.082
4.64LeuGln: 4.64 ± 1.896
5.414LeuArg: 5.414 ± 2.95
5.414LeuSer: 5.414 ± 1.599
3.094LeuThr: 3.094 ± 0.454
3.094LeuVal: 3.094 ± 1.777
2.32LeuTrp: 2.32 ± 0.957
4.64LeuTyr: 4.64 ± 0.199
0.0LeuXaa: 0.0 ± 0.0
Met
2.32MetAla: 2.32 ± 0.1
0.773MetCys: 0.773 ± 0.666
3.094MetAsp: 3.094 ± 0.753
1.547MetGlu: 1.547 ± 0.632
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.773MetIle: 0.773 ± 0.666
0.773MetLys: 0.773 ± 0.541
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.773MetAsn: 0.773 ± 0.666
1.547MetPro: 1.547 ± 0.632
2.32MetGln: 2.32 ± 0.957
0.773MetArg: 0.773 ± 0.541
0.773MetSer: 0.773 ± 0.593
1.547MetThr: 1.547 ± 0.584
0.773MetVal: 0.773 ± 0.593
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.867AsnAla: 3.867 ± 0.509
1.547AsnCys: 1.547 ± 1.333
1.547AsnAsp: 1.547 ± 0.632
1.547AsnGlu: 1.547 ± 0.632
4.64AsnPhe: 4.64 ± 1.091
0.773AsnGly: 0.773 ± 0.541
0.773AsnHis: 0.773 ± 0.541
3.094AsnIle: 3.094 ± 1.777
1.547AsnLys: 1.547 ± 0.632
6.187AsnLeu: 6.187 ± 0.655
1.547AsnMet: 1.547 ± 0.632
1.547AsnAsn: 1.547 ± 0.598
1.547AsnPro: 1.547 ± 0.632
3.094AsnGln: 3.094 ± 0.605
3.094AsnArg: 3.094 ± 0.454
4.64AsnSer: 4.64 ± 0.199
3.867AsnThr: 3.867 ± 1.462
3.094AsnVal: 3.094 ± 0.753
1.547AsnTrp: 1.547 ± 0.584
3.094AsnTyr: 3.094 ± 0.753
0.0AsnXaa: 0.0 ± 0.0
Pro
1.547ProAla: 1.547 ± 0.598
1.547ProCys: 1.547 ± 0.632
0.773ProAsp: 0.773 ± 0.541
5.414ProGlu: 5.414 ± 1.214
2.32ProPhe: 2.32 ± 1.029
1.547ProGly: 1.547 ± 1.333
1.547ProHis: 1.547 ± 0.598
2.32ProIle: 2.32 ± 1.999
3.094ProLys: 3.094 ± 1.598
5.414ProLeu: 5.414 ± 1.574
2.32ProMet: 2.32 ± 0.393
4.64ProAsn: 4.64 ± 1.795
3.094ProPro: 3.094 ± 2.374
1.547ProGln: 1.547 ± 0.598
6.961ProArg: 6.961 ± 2.721
1.547ProSer: 1.547 ± 0.584
6.187ProThr: 6.187 ± 0.82
0.773ProVal: 0.773 ± 0.541
1.547ProTrp: 1.547 ± 1.082
2.32ProTyr: 2.32 ± 0.957
0.0ProXaa: 0.0 ± 0.0
Gln
5.414GlnAla: 5.414 ± 1.342
0.773GlnCys: 0.773 ± 0.593
1.547GlnAsp: 1.547 ± 0.598
3.094GlnGlu: 3.094 ± 0.605
1.547GlnPhe: 1.547 ± 0.632
3.867GlnGly: 3.867 ± 1.195
4.64GlnHis: 4.64 ± 1.008
3.867GlnIle: 3.867 ± 0.725
0.773GlnLys: 0.773 ± 0.666
2.32GlnLeu: 2.32 ± 0.957
0.773GlnMet: 0.773 ± 0.666
1.547GlnAsn: 1.547 ± 0.632
1.547GlnPro: 1.547 ± 0.632
0.0GlnGln: 0.0 ± 0.0
3.867GlnArg: 3.867 ± 1.418
0.773GlnSer: 0.773 ± 0.593
0.773GlnThr: 0.773 ± 0.593
0.773GlnVal: 0.773 ± 0.593
0.0GlnTrp: 0.0 ± 0.0
1.547GlnTyr: 1.547 ± 0.584
0.0GlnXaa: 0.0 ± 0.0
Arg
6.961ArgAla: 6.961 ± 0.857
0.773ArgCys: 0.773 ± 0.541
6.187ArgAsp: 6.187 ± 0.443
3.094ArgGlu: 3.094 ± 0.605
1.547ArgPhe: 1.547 ± 0.598
3.094ArgGly: 3.094 ± 2.164
0.773ArgHis: 0.773 ± 0.666
3.094ArgIle: 3.094 ± 1.197
3.867ArgLys: 3.867 ± 1.195
4.64ArgLeu: 4.64 ± 1.008
0.0ArgMet: 0.0 ± 0.0
2.32ArgAsn: 2.32 ± 1.999
6.187ArgPro: 6.187 ± 1.677
3.094ArgGln: 3.094 ± 0.605
6.187ArgArg: 6.187 ± 0.82
3.094ArgSer: 3.094 ± 1.169
6.187ArgThr: 6.187 ± 1.505
1.547ArgVal: 1.547 ± 1.187
0.773ArgTrp: 0.773 ± 0.666
3.094ArgTyr: 3.094 ± 0.454
0.0ArgXaa: 0.0 ± 0.0
Ser
5.414SerAla: 5.414 ± 1.214
0.0SerCys: 0.0 ± 0.0
0.0SerAsp: 0.0 ± 0.0
3.867SerGlu: 3.867 ± 1.195
2.32SerPhe: 2.32 ± 1.046
5.414SerGly: 5.414 ± 1.214
1.547SerHis: 1.547 ± 0.632
3.867SerIle: 3.867 ± 0.509
3.867SerLys: 3.867 ± 0.993
3.867SerLeu: 3.867 ± 1.9
0.773SerMet: 0.773 ± 0.541
3.094SerAsn: 3.094 ± 0.605
1.547SerPro: 1.547 ± 0.584
2.32SerGln: 2.32 ± 0.1
4.64SerArg: 4.64 ± 1.914
6.187SerSer: 6.187 ± 2.338
7.734SerThr: 7.734 ± 3.3
3.867SerVal: 3.867 ± 0.993
1.547SerTrp: 1.547 ± 0.632
3.867SerTyr: 3.867 ± 0.993
0.0SerXaa: 0.0 ± 0.0
Thr
6.961ThrAla: 6.961 ± 2.171
0.773ThrCys: 0.773 ± 0.666
3.867ThrAsp: 3.867 ± 0.509
10.054ThrGlu: 10.054 ± 2.403
6.187ThrPhe: 6.187 ± 0.907
6.187ThrGly: 6.187 ± 1.677
2.32ThrHis: 2.32 ± 0.1
3.094ThrIle: 3.094 ± 0.753
3.867ThrLys: 3.867 ± 0.993
3.094ThrLeu: 3.094 ± 1.264
0.773ThrMet: 0.773 ± 0.593
3.867ThrAsn: 3.867 ± 1.418
3.867ThrPro: 3.867 ± 0.725
5.414ThrGln: 5.414 ± 1.574
2.32ThrArg: 2.32 ± 1.145
9.281ThrSer: 9.281 ± 2.287
4.64ThrThr: 4.64 ± 3.078
3.867ThrVal: 3.867 ± 1.462
0.0ThrTrp: 0.0 ± 0.0
2.32ThrTyr: 2.32 ± 1.623
0.0ThrXaa: 0.0 ± 0.0
Val
0.773ValAla: 0.773 ± 0.593
0.773ValCys: 0.773 ± 0.541
0.773ValAsp: 0.773 ± 0.593
0.773ValGlu: 0.773 ± 0.666
0.773ValPhe: 0.773 ± 0.666
0.773ValGly: 0.773 ± 0.541
1.547ValHis: 1.547 ± 0.632
3.867ValIle: 3.867 ± 0.509
1.547ValLys: 1.547 ± 1.082
3.867ValLeu: 3.867 ± 0.619
1.547ValMet: 1.547 ± 0.632
2.32ValAsn: 2.32 ± 1.145
3.867ValPro: 3.867 ± 1.9
0.773ValGln: 0.773 ± 0.541
5.414ValArg: 5.414 ± 1.091
2.32ValSer: 2.32 ± 0.926
4.64ValThr: 4.64 ± 0.887
2.32ValVal: 2.32 ± 0.926
0.773ValTrp: 0.773 ± 0.541
1.547ValTyr: 1.547 ± 1.187
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.32TrpAsp: 2.32 ± 1.029
0.0TrpGlu: 0.0 ± 0.0
3.867TrpPhe: 3.867 ± 0.725
0.773TrpGly: 0.773 ± 0.541
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.773TrpLys: 0.773 ± 0.541
3.094TrpLeu: 3.094 ± 0.753
0.0TrpMet: 0.0 ± 0.0
0.773TrpAsn: 0.773 ± 0.541
0.0TrpPro: 0.0 ± 0.0
1.547TrpGln: 1.547 ± 0.598
1.547TrpArg: 1.547 ± 0.598
3.867TrpSer: 3.867 ± 0.509
0.773TrpThr: 0.773 ± 0.593
0.773TrpVal: 0.773 ± 0.593
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.867TyrAla: 3.867 ± 1.195
1.547TyrCys: 1.547 ± 0.632
3.094TyrAsp: 3.094 ± 1.777
3.094TyrGlu: 3.094 ± 2.164
2.32TyrPhe: 2.32 ± 1.145
1.547TyrGly: 1.547 ± 0.598
0.773TyrHis: 0.773 ± 0.593
3.867TyrIle: 3.867 ± 1.195
0.0TyrLys: 0.0 ± 0.0
4.64TyrLeu: 4.64 ± 0.887
0.773TyrMet: 0.773 ± 0.593
4.64TyrAsn: 4.64 ± 2.058
1.547TyrPro: 1.547 ± 1.082
1.547TyrGln: 1.547 ± 0.632
3.867TyrArg: 3.867 ± 0.509
0.773TyrSer: 0.773 ± 0.541
7.734TyrThr: 7.734 ± 2.872
2.32TyrVal: 2.32 ± 1.046
0.0TyrTrp: 0.0 ± 0.0
0.773TyrTyr: 0.773 ± 0.541
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1294 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski