Amino acid dipepetide frequency for Avon-Heathcote Estuary associated circular virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.722AlaAla: 7.722 ± 0.301
0.0AlaCys: 0.0 ± 0.0
5.792AlaAsp: 5.792 ± 4.253
5.792AlaGlu: 5.792 ± 1.117
3.861AlaPhe: 3.861 ± 2.836
3.861AlaGly: 3.861 ± 0.15
0.0AlaHis: 0.0 ± 0.0
1.931AlaIle: 1.931 ± 1.267
1.931AlaLys: 1.931 ± 1.418
1.931AlaLeu: 1.931 ± 1.267
3.861AlaMet: 3.861 ± 2.23
0.0AlaAsn: 0.0 ± 0.0
0.0AlaPro: 0.0 ± 0.0
1.931AlaGln: 1.931 ± 1.418
5.792AlaArg: 5.792 ± 1.568
0.0AlaSer: 0.0 ± 0.0
3.861AlaThr: 3.861 ± 2.836
5.792AlaVal: 5.792 ± 1.568
1.931AlaTrp: 1.931 ± 1.267
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.931CysGly: 1.931 ± 1.267
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.931CysLys: 1.931 ± 1.267
0.0CysLeu: 0.0 ± 0.0
3.861CysMet: 3.861 ± 2.535
0.0CysAsn: 0.0 ± 0.0
1.931CysPro: 1.931 ± 1.267
1.931CysGln: 1.931 ± 1.267
0.0CysArg: 0.0 ± 0.0
1.931CysSer: 1.931 ± 1.267
3.861CysThr: 3.861 ± 2.535
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
1.931AspAsp: 1.931 ± 1.267
3.861AspGlu: 3.861 ± 2.535
3.861AspPhe: 3.861 ± 2.535
0.0AspGly: 0.0 ± 0.0
0.0AspHis: 0.0 ± 0.0
1.931AspIle: 1.931 ± 1.267
3.861AspLys: 3.861 ± 2.836
1.931AspLeu: 1.931 ± 1.267
1.931AspMet: 1.931 ± 1.418
1.931AspAsn: 1.931 ± 1.418
7.722AspPro: 7.722 ± 0.301
0.0AspGln: 0.0 ± 0.0
5.792AspArg: 5.792 ± 1.117
1.931AspSer: 1.931 ± 1.418
1.931AspThr: 1.931 ± 1.418
7.722AspVal: 7.722 ± 0.301
1.931AspTrp: 1.931 ± 1.267
1.931AspTyr: 1.931 ± 1.418
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
0.0GluCys: 0.0 ± 0.0
1.931GluAsp: 1.931 ± 1.267
5.792GluGlu: 5.792 ± 3.802
1.931GluPhe: 1.931 ± 1.418
3.861GluGly: 3.861 ± 2.535
1.931GluHis: 1.931 ± 1.267
3.861GluIle: 3.861 ± 2.535
1.931GluLys: 1.931 ± 1.267
1.931GluLeu: 1.931 ± 1.267
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
5.792GluPro: 5.792 ± 1.117
3.861GluGln: 3.861 ± 0.15
3.861GluArg: 3.861 ± 2.535
1.931GluSer: 1.931 ± 1.267
7.722GluThr: 7.722 ± 2.986
5.792GluVal: 5.792 ± 1.117
3.861GluTrp: 3.861 ± 2.535
5.792GluTyr: 5.792 ± 3.802
0.0GluXaa: 0.0 ± 0.0
Phe
3.861PheAla: 3.861 ± 2.836
0.0PheCys: 0.0 ± 0.0
7.722PheAsp: 7.722 ± 0.301
3.861PheGlu: 3.861 ± 2.535
1.931PhePhe: 1.931 ± 1.267
1.931PheGly: 1.931 ± 1.418
0.0PheHis: 0.0 ± 0.0
1.931PheIle: 1.931 ± 1.267
9.653PheLys: 9.653 ± 1.718
1.931PheLeu: 1.931 ± 1.267
0.0PheMet: 0.0 ± 0.0
5.792PheAsn: 5.792 ± 1.568
1.931PhePro: 1.931 ± 1.267
1.931PheGln: 1.931 ± 1.418
3.861PheArg: 3.861 ± 2.836
1.931PheSer: 1.931 ± 1.418
1.931PheThr: 1.931 ± 1.267
0.0PheVal: 0.0 ± 0.0
1.931PheTrp: 1.931 ± 1.267
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.931GlyAla: 1.931 ± 1.267
1.931GlyCys: 1.931 ± 1.267
5.792GlyAsp: 5.792 ± 1.117
5.792GlyGlu: 5.792 ± 3.802
5.792GlyPhe: 5.792 ± 1.117
1.931GlyGly: 1.931 ± 1.267
1.931GlyHis: 1.931 ± 1.418
0.0GlyIle: 0.0 ± 0.0
9.653GlyLys: 9.653 ± 6.337
3.861GlyLeu: 3.861 ± 2.836
1.931GlyMet: 1.931 ± 1.267
1.931GlyAsn: 1.931 ± 1.418
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
3.861GlyArg: 3.861 ± 0.15
7.722GlySer: 7.722 ± 5.07
7.722GlyThr: 7.722 ± 2.986
0.0GlyVal: 0.0 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
1.931GlyTyr: 1.931 ± 1.267
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.931HisGlu: 1.931 ± 1.267
1.931HisPhe: 1.931 ± 1.418
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
5.792HisLys: 5.792 ± 3.802
1.931HisLeu: 1.931 ± 1.267
0.0HisMet: 0.0 ± 0.0
1.931HisAsn: 1.931 ± 1.418
3.861HisPro: 3.861 ± 2.836
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.931HisVal: 1.931 ± 1.267
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.861IleAla: 3.861 ± 2.535
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
1.931IleGlu: 1.931 ± 1.418
0.0IlePhe: 0.0 ± 0.0
3.861IleGly: 3.861 ± 2.535
1.931IleHis: 1.931 ± 1.418
1.931IleIle: 1.931 ± 1.267
3.861IleLys: 3.861 ± 0.15
1.931IleLeu: 1.931 ± 1.267
1.931IleMet: 1.931 ± 1.418
0.0IleAsn: 0.0 ± 0.0
1.931IlePro: 1.931 ± 1.418
3.861IleGln: 3.861 ± 2.836
1.931IleArg: 1.931 ± 1.418
0.0IleSer: 0.0 ± 0.0
9.653IleThr: 9.653 ± 0.967
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.931LysAla: 1.931 ± 1.267
0.0LysCys: 0.0 ± 0.0
3.861LysAsp: 3.861 ± 2.836
5.792LysGlu: 5.792 ± 3.802
1.931LysPhe: 1.931 ± 1.418
1.931LysGly: 1.931 ± 1.267
3.861LysHis: 3.861 ± 2.535
5.792LysIle: 5.792 ± 4.253
3.861LysLys: 3.861 ± 0.15
1.931LysLeu: 1.931 ± 1.267
3.861LysMet: 3.861 ± 3.237
5.792LysAsn: 5.792 ± 1.117
0.0LysPro: 0.0 ± 0.0
5.792LysGln: 5.792 ± 1.117
3.861LysArg: 3.861 ± 0.15
9.653LysSer: 9.653 ± 3.652
5.792LysThr: 5.792 ± 1.568
7.722LysVal: 7.722 ± 2.385
1.931LysTrp: 1.931 ± 1.267
5.792LysTyr: 5.792 ± 1.568
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
0.0LeuCys: 0.0 ± 0.0
0.0LeuAsp: 0.0 ± 0.0
3.861LeuGlu: 3.861 ± 2.535
0.0LeuPhe: 0.0 ± 0.0
7.722LeuGly: 7.722 ± 0.301
1.931LeuHis: 1.931 ± 1.418
3.861LeuIle: 3.861 ± 2.836
0.0LeuLys: 0.0 ± 0.0
5.792LeuLeu: 5.792 ± 1.117
0.0LeuMet: 0.0 ± 0.0
0.0LeuAsn: 0.0 ± 0.0
1.931LeuPro: 1.931 ± 1.418
5.792LeuGln: 5.792 ± 1.117
1.931LeuArg: 1.931 ± 1.418
3.861LeuSer: 3.861 ± 2.836
1.931LeuThr: 1.931 ± 1.267
1.931LeuVal: 1.931 ± 1.267
3.861LeuTrp: 3.861 ± 2.535
1.931LeuTyr: 1.931 ± 1.418
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.931MetGlu: 1.931 ± 1.267
5.792MetPhe: 5.792 ± 1.568
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
7.722MetLys: 7.722 ± 2.385
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.931MetAsn: 1.931 ± 1.418
3.861MetPro: 3.861 ± 0.15
1.931MetGln: 1.931 ± 1.267
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
3.861MetVal: 3.861 ± 0.15
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.931AsnAla: 1.931 ± 1.418
0.0AsnCys: 0.0 ± 0.0
3.861AsnAsp: 3.861 ± 0.15
1.931AsnGlu: 1.931 ± 1.267
3.861AsnPhe: 3.861 ± 2.535
3.861AsnGly: 3.861 ± 0.15
1.931AsnHis: 1.931 ± 1.267
0.0AsnIle: 0.0 ± 0.0
3.861AsnLys: 3.861 ± 0.15
7.722AsnLeu: 7.722 ± 5.671
3.861AsnMet: 3.861 ± 2.836
3.861AsnAsn: 3.861 ± 2.836
3.861AsnPro: 3.861 ± 0.15
0.0AsnGln: 0.0 ± 0.0
0.0AsnArg: 0.0 ± 0.0
3.861AsnSer: 3.861 ± 2.836
1.931AsnThr: 1.931 ± 1.418
7.722AsnVal: 7.722 ± 2.986
1.931AsnTrp: 1.931 ± 1.267
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
7.722ProAla: 7.722 ± 5.671
1.931ProCys: 1.931 ± 1.267
1.931ProAsp: 1.931 ± 1.267
5.792ProGlu: 5.792 ± 3.802
0.0ProPhe: 0.0 ± 0.0
1.931ProGly: 1.931 ± 1.267
1.931ProHis: 1.931 ± 1.267
0.0ProIle: 0.0 ± 0.0
1.931ProLys: 1.931 ± 1.267
1.931ProLeu: 1.931 ± 1.418
0.0ProMet: 0.0 ± 0.0
3.861ProAsn: 3.861 ± 0.15
0.0ProPro: 0.0 ± 0.0
1.931ProGln: 1.931 ± 1.418
5.792ProArg: 5.792 ± 3.802
0.0ProSer: 0.0 ± 0.0
5.792ProThr: 5.792 ± 1.568
1.931ProVal: 1.931 ± 1.418
0.0ProTrp: 0.0 ± 0.0
1.931ProTyr: 1.931 ± 1.418
0.0ProXaa: 0.0 ± 0.0
Gln
5.792GlnAla: 5.792 ± 4.253
1.931GlnCys: 1.931 ± 1.267
0.0GlnAsp: 0.0 ± 0.0
1.931GlnGlu: 1.931 ± 1.418
1.931GlnPhe: 1.931 ± 1.267
7.722GlnGly: 7.722 ± 0.301
0.0GlnHis: 0.0 ± 0.0
1.931GlnIle: 1.931 ± 1.418
0.0GlnLys: 0.0 ± 0.0
0.0GlnLeu: 0.0 ± 0.0
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.931GlnPro: 1.931 ± 1.267
1.931GlnGln: 1.931 ± 1.418
1.931GlnArg: 1.931 ± 1.418
1.931GlnSer: 1.931 ± 1.418
3.861GlnThr: 3.861 ± 2.836
3.861GlnVal: 3.861 ± 0.15
0.0GlnTrp: 0.0 ± 0.0
3.861GlnTyr: 3.861 ± 2.535
0.0GlnXaa: 0.0 ± 0.0
Arg
7.722ArgAla: 7.722 ± 0.301
0.0ArgCys: 0.0 ± 0.0
5.792ArgAsp: 5.792 ± 1.117
3.861ArgGlu: 3.861 ± 0.15
3.861ArgPhe: 3.861 ± 0.15
3.861ArgGly: 3.861 ± 0.15
0.0ArgHis: 0.0 ± 0.0
5.792ArgIle: 5.792 ± 1.117
5.792ArgLys: 5.792 ± 1.568
3.861ArgLeu: 3.861 ± 0.15
0.0ArgMet: 0.0 ± 0.0
9.653ArgAsn: 9.653 ± 1.718
0.0ArgPro: 0.0 ± 0.0
0.0ArgGln: 0.0 ± 0.0
15.444ArgArg: 15.444 ± 3.287
0.0ArgSer: 0.0 ± 0.0
1.931ArgThr: 1.931 ± 1.418
1.931ArgVal: 1.931 ± 1.418
0.0ArgTrp: 0.0 ± 0.0
1.931ArgTyr: 1.931 ± 1.267
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
1.931SerAsp: 1.931 ± 1.418
3.861SerGlu: 3.861 ± 2.836
0.0SerPhe: 0.0 ± 0.0
3.861SerGly: 3.861 ± 2.535
0.0SerHis: 0.0 ± 0.0
3.861SerIle: 3.861 ± 2.535
3.861SerLys: 3.861 ± 2.836
1.931SerLeu: 1.931 ± 1.418
3.861SerMet: 3.861 ± 2.535
5.792SerAsn: 5.792 ± 1.117
3.861SerPro: 3.861 ± 2.535
1.931SerGln: 1.931 ± 1.418
1.931SerArg: 1.931 ± 1.267
3.861SerSer: 3.861 ± 2.836
1.931SerThr: 1.931 ± 1.418
7.722SerVal: 7.722 ± 2.986
1.931SerTrp: 1.931 ± 1.267
3.861SerTyr: 3.861 ± 0.15
0.0SerXaa: 0.0 ± 0.0
Thr
7.722ThrAla: 7.722 ± 2.986
0.0ThrCys: 0.0 ± 0.0
1.931ThrAsp: 1.931 ± 1.267
1.931ThrGlu: 1.931 ± 1.267
3.861ThrPhe: 3.861 ± 2.836
0.0ThrGly: 0.0 ± 0.0
1.931ThrHis: 1.931 ± 1.418
3.861ThrIle: 3.861 ± 2.836
3.861ThrLys: 3.861 ± 0.15
1.931ThrLeu: 1.931 ± 1.418
0.0ThrMet: 0.0 ± 0.0
5.792ThrAsn: 5.792 ± 4.253
1.931ThrPro: 1.931 ± 1.418
3.861ThrGln: 3.861 ± 0.15
5.792ThrArg: 5.792 ± 1.117
13.514ThrSer: 13.514 ± 0.816
7.722ThrThr: 7.722 ± 2.986
3.861ThrVal: 3.861 ± 2.836
0.0ThrTrp: 0.0 ± 0.0
3.861ThrTyr: 3.861 ± 2.535
0.0ThrXaa: 0.0 ± 0.0
Val
3.861ValAla: 3.861 ± 0.15
3.861ValCys: 3.861 ± 2.535
1.931ValAsp: 1.931 ± 1.267
1.931ValGlu: 1.931 ± 1.418
7.722ValPhe: 7.722 ± 2.385
5.792ValGly: 5.792 ± 1.568
0.0ValHis: 0.0 ± 0.0
1.931ValIle: 1.931 ± 1.418
7.722ValLys: 7.722 ± 2.385
1.931ValLeu: 1.931 ± 1.267
0.0ValMet: 0.0 ± 0.0
5.792ValAsn: 5.792 ± 1.568
3.861ValPro: 3.861 ± 0.15
3.861ValGln: 3.861 ± 2.836
5.792ValArg: 5.792 ± 4.253
3.861ValSer: 3.861 ± 2.836
1.931ValThr: 1.931 ± 1.267
9.653ValVal: 9.653 ± 4.404
3.861ValTrp: 3.861 ± 0.15
1.931ValTyr: 1.931 ± 1.418
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
5.792TrpCys: 5.792 ± 3.802
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.931TrpPhe: 1.931 ± 1.418
5.792TrpGly: 5.792 ± 3.802
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.931TrpLeu: 1.931 ± 1.267
0.0TrpMet: 0.0 ± 0.0
1.931TrpAsn: 1.931 ± 1.267
1.931TrpPro: 1.931 ± 1.267
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.931TrpThr: 1.931 ± 1.418
1.931TrpVal: 1.931 ± 1.267
1.931TrpTrp: 1.931 ± 1.267
1.931TrpTyr: 1.931 ± 1.267
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.931TyrAla: 1.931 ± 1.418
1.931TyrCys: 1.931 ± 1.267
5.792TyrAsp: 5.792 ± 1.117
0.0TyrGlu: 0.0 ± 0.0
1.931TyrPhe: 1.931 ± 1.418
3.861TyrGly: 3.861 ± 2.535
1.931TyrHis: 1.931 ± 1.267
0.0TyrIle: 0.0 ± 0.0
5.792TyrLys: 5.792 ± 3.802
1.931TyrLeu: 1.931 ± 1.418
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
3.861TyrArg: 3.861 ± 0.15
0.0TyrSer: 0.0 ± 0.0
1.931TyrThr: 1.931 ± 1.267
3.861TyrVal: 3.861 ± 0.15
1.931TyrTrp: 1.931 ± 1.418
1.931TyrTyr: 1.931 ± 1.418
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (519 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski