Amino acid dipepetide frequency for Fowl aviadenovirus D

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.752AlaAla: 8.752 ± 1.404
1.313AlaCys: 1.313 ± 0.567
4.485AlaAsp: 4.485 ± 0.725
5.689AlaGlu: 5.689 ± 0.979
2.954AlaPhe: 2.954 ± 0.444
4.923AlaGly: 4.923 ± 1.002
1.313AlaHis: 1.313 ± 0.439
4.376AlaIle: 4.376 ± 1.058
3.282AlaLys: 3.282 ± 0.668
7.111AlaLeu: 7.111 ± 0.937
2.188AlaMet: 2.188 ± 0.903
3.61AlaAsn: 3.61 ± 0.696
6.017AlaPro: 6.017 ± 1.032
3.173AlaGln: 3.173 ± 0.826
4.157AlaArg: 4.157 ± 0.579
5.251AlaSer: 5.251 ± 0.974
5.032AlaThr: 5.032 ± 0.771
5.579AlaVal: 5.579 ± 0.949
0.656AlaTrp: 0.656 ± 0.248
4.266AlaTyr: 4.266 ± 0.647
0.0AlaXaa: 0.0 ± 0.0
Cys
0.656CysAla: 0.656 ± 0.237
0.219CysCys: 0.219 ± 0.16
1.422CysAsp: 1.422 ± 0.421
0.219CysGlu: 0.219 ± 0.143
0.656CysPhe: 0.656 ± 0.247
1.203CysGly: 1.203 ± 0.469
0.766CysHis: 0.766 ± 0.388
0.547CysIle: 0.547 ± 0.27
0.547CysLys: 0.547 ± 0.263
0.875CysLeu: 0.875 ± 0.353
0.656CysMet: 0.656 ± 0.384
0.547CysAsn: 0.547 ± 0.332
1.532CysPro: 1.532 ± 0.469
0.438CysGln: 0.438 ± 0.276
1.094CysArg: 1.094 ± 0.344
1.094CysSer: 1.094 ± 0.252
0.766CysThr: 0.766 ± 0.278
0.766CysVal: 0.766 ± 0.431
0.219CysTrp: 0.219 ± 0.132
0.766CysTyr: 0.766 ± 0.269
0.0CysXaa: 0.0 ± 0.0
Asp
4.485AspAla: 4.485 ± 0.819
0.547AspCys: 0.547 ± 0.226
2.735AspAsp: 2.735 ± 0.593
3.72AspGlu: 3.72 ± 1.073
2.516AspPhe: 2.516 ± 0.366
3.501AspGly: 3.501 ± 0.517
1.532AspHis: 1.532 ± 0.399
2.626AspIle: 2.626 ± 0.614
2.516AspLys: 2.516 ± 0.615
4.813AspLeu: 4.813 ± 0.645
1.203AspMet: 1.203 ± 0.335
1.532AspAsn: 1.532 ± 0.545
5.798AspPro: 5.798 ± 0.838
1.641AspGln: 1.641 ± 0.399
3.829AspArg: 3.829 ± 0.722
4.813AspSer: 4.813 ± 0.712
3.72AspThr: 3.72 ± 0.831
3.173AspVal: 3.173 ± 0.772
0.547AspTrp: 0.547 ± 0.177
1.75AspTyr: 1.75 ± 0.414
0.0AspXaa: 0.0 ± 0.0
Glu
4.704GluAla: 4.704 ± 0.67
0.328GluCys: 0.328 ± 0.143
4.266GluAsp: 4.266 ± 0.955
8.424GluGlu: 8.424 ± 2.676
1.641GluPhe: 1.641 ± 0.458
4.157GluGly: 4.157 ± 0.663
1.422GluHis: 1.422 ± 0.397
2.297GluIle: 2.297 ± 0.432
1.969GluLys: 1.969 ± 0.611
5.47GluLeu: 5.47 ± 0.85
1.313GluMet: 1.313 ± 0.351
3.72GluAsn: 3.72 ± 0.705
2.626GluPro: 2.626 ± 0.72
2.079GluGln: 2.079 ± 0.54
3.61GluArg: 3.61 ± 0.89
4.704GluSer: 4.704 ± 0.92
3.391GluThr: 3.391 ± 0.632
3.063GluVal: 3.063 ± 0.659
0.766GluTrp: 0.766 ± 0.233
1.532GluTyr: 1.532 ± 0.377
0.0GluXaa: 0.0 ± 0.0
Phe
3.501PheAla: 3.501 ± 0.549
0.328PheCys: 0.328 ± 0.194
2.844PheAsp: 2.844 ± 0.739
2.188PheGlu: 2.188 ± 0.409
1.75PhePhe: 1.75 ± 0.314
1.313PheGly: 1.313 ± 0.389
1.75PheHis: 1.75 ± 0.421
1.094PheIle: 1.094 ± 0.345
2.297PheLys: 2.297 ± 0.44
4.595PheLeu: 4.595 ± 0.802
1.203PheMet: 1.203 ± 0.32
2.297PheAsn: 2.297 ± 0.449
1.75PhePro: 1.75 ± 0.41
1.094PheGln: 1.094 ± 0.318
3.282PheArg: 3.282 ± 0.404
1.86PheSer: 1.86 ± 0.396
2.297PheThr: 2.297 ± 0.514
3.282PheVal: 3.282 ± 0.692
0.875PheTrp: 0.875 ± 0.265
1.75PheTyr: 1.75 ± 0.316
0.0PheXaa: 0.0 ± 0.0
Gly
6.892GlyAla: 6.892 ± 0.959
0.766GlyCys: 0.766 ± 0.353
3.173GlyAsp: 3.173 ± 0.809
3.72GlyGlu: 3.72 ± 1.507
2.516GlyPhe: 2.516 ± 0.458
6.783GlyGly: 6.783 ± 1.241
1.094GlyHis: 1.094 ± 0.502
2.297GlyIle: 2.297 ± 0.638
1.641GlyLys: 1.641 ± 0.469
4.048GlyLeu: 4.048 ± 0.845
1.641GlyMet: 1.641 ± 0.346
2.407GlyAsn: 2.407 ± 0.572
2.954GlyPro: 2.954 ± 0.795
1.75GlyGln: 1.75 ± 0.418
4.048GlyArg: 4.048 ± 0.671
4.704GlySer: 4.704 ± 0.726
4.704GlyThr: 4.704 ± 0.851
5.907GlyVal: 5.907 ± 1.001
1.422GlyTrp: 1.422 ± 0.358
2.735GlyTyr: 2.735 ± 0.505
0.0GlyXaa: 0.0 ± 0.0
His
1.422HisAla: 1.422 ± 0.29
0.328HisCys: 0.328 ± 0.189
1.422HisAsp: 1.422 ± 0.4
1.203HisGlu: 1.203 ± 0.323
0.656HisPhe: 0.656 ± 0.259
1.75HisGly: 1.75 ± 0.415
1.203HisHis: 1.203 ± 0.282
0.985HisIle: 0.985 ± 0.307
0.547HisLys: 0.547 ± 0.27
1.969HisLeu: 1.969 ± 0.528
0.328HisMet: 0.328 ± 0.175
1.313HisAsn: 1.313 ± 0.277
1.969HisPro: 1.969 ± 0.541
0.985HisGln: 0.985 ± 0.509
2.188HisArg: 2.188 ± 0.51
1.094HisSer: 1.094 ± 0.236
1.422HisThr: 1.422 ± 0.374
2.297HisVal: 2.297 ± 0.647
0.219HisTrp: 0.219 ± 0.146
0.985HisTyr: 0.985 ± 0.229
0.0HisXaa: 0.0 ± 0.0
Ile
3.829IleAla: 3.829 ± 0.657
0.875IleCys: 0.875 ± 0.336
2.079IleAsp: 2.079 ± 0.413
1.75IleGlu: 1.75 ± 0.337
1.313IlePhe: 1.313 ± 0.331
2.516IleGly: 2.516 ± 0.548
0.656IleHis: 0.656 ± 0.25
1.313IleIle: 1.313 ± 0.405
1.313IleLys: 1.313 ± 0.427
3.173IleLeu: 3.173 ± 0.534
0.547IleMet: 0.547 ± 0.336
1.532IleAsn: 1.532 ± 0.566
3.501IlePro: 3.501 ± 0.568
1.532IleGln: 1.532 ± 0.525
3.173IleArg: 3.173 ± 0.47
2.735IleSer: 2.735 ± 0.439
2.297IleThr: 2.297 ± 0.408
2.626IleVal: 2.626 ± 0.554
0.219IleTrp: 0.219 ± 0.166
1.641IleTyr: 1.641 ± 0.348
0.0IleXaa: 0.0 ± 0.0
Lys
2.516LysAla: 2.516 ± 0.745
0.656LysCys: 0.656 ± 0.273
1.532LysAsp: 1.532 ± 0.376
2.407LysGlu: 2.407 ± 0.704
2.407LysPhe: 2.407 ± 0.65
2.407LysGly: 2.407 ± 0.61
0.438LysHis: 0.438 ± 0.205
1.203LysIle: 1.203 ± 0.245
2.407LysLys: 2.407 ± 0.727
3.72LysLeu: 3.72 ± 0.69
1.203LysMet: 1.203 ± 0.353
1.969LysAsn: 1.969 ± 0.425
2.079LysPro: 2.079 ± 0.452
0.985LysGln: 0.985 ± 0.292
3.61LysArg: 3.61 ± 0.753
1.969LysSer: 1.969 ± 0.624
3.173LysThr: 3.173 ± 0.574
1.969LysVal: 1.969 ± 0.442
0.438LysTrp: 0.438 ± 0.213
2.188LysTyr: 2.188 ± 0.596
0.0LysXaa: 0.0 ± 0.0
Leu
5.798LeuAla: 5.798 ± 0.649
0.985LeuCys: 0.985 ± 0.231
4.595LeuAsp: 4.595 ± 0.555
4.376LeuGlu: 4.376 ± 0.606
4.157LeuPhe: 4.157 ± 0.627
4.485LeuGly: 4.485 ± 0.559
2.297LeuHis: 2.297 ± 0.593
2.516LeuIle: 2.516 ± 0.425
4.266LeuLys: 4.266 ± 0.799
6.345LeuLeu: 6.345 ± 0.81
1.86LeuMet: 1.86 ± 0.41
3.61LeuAsn: 3.61 ± 0.45
4.704LeuPro: 4.704 ± 0.482
4.595LeuGln: 4.595 ± 0.551
5.251LeuArg: 5.251 ± 0.916
6.783LeuSer: 6.783 ± 0.568
6.345LeuThr: 6.345 ± 0.998
3.829LeuVal: 3.829 ± 0.689
1.641LeuTrp: 1.641 ± 0.298
2.844LeuTyr: 2.844 ± 0.595
0.0LeuXaa: 0.0 ± 0.0
Met
2.735MetAla: 2.735 ± 0.674
0.219MetCys: 0.219 ± 0.168
1.532MetAsp: 1.532 ± 0.403
0.656MetGlu: 0.656 ± 0.323
0.875MetPhe: 0.875 ± 0.296
1.422MetGly: 1.422 ± 0.435
0.875MetHis: 0.875 ± 0.344
0.875MetIle: 0.875 ± 0.32
1.094MetLys: 1.094 ± 0.348
1.969MetLeu: 1.969 ± 0.377
0.438MetMet: 0.438 ± 0.179
0.875MetAsn: 0.875 ± 0.238
1.094MetPro: 1.094 ± 0.294
0.985MetGln: 0.985 ± 0.291
2.079MetArg: 2.079 ± 0.477
1.313MetSer: 1.313 ± 0.38
1.203MetThr: 1.203 ± 0.393
1.422MetVal: 1.422 ± 0.429
0.109MetTrp: 0.109 ± 0.11
1.094MetTyr: 1.094 ± 0.352
0.0MetXaa: 0.0 ± 0.0
Asn
3.61AsnAla: 3.61 ± 0.716
1.203AsnCys: 1.203 ± 0.361
1.969AsnAsp: 1.969 ± 0.564
1.969AsnGlu: 1.969 ± 0.633
1.532AsnPhe: 1.532 ± 0.671
2.954AsnGly: 2.954 ± 0.746
0.985AsnHis: 0.985 ± 0.248
1.532AsnIle: 1.532 ± 0.617
1.313AsnLys: 1.313 ± 0.403
3.063AsnLeu: 3.063 ± 0.711
0.875AsnMet: 0.875 ± 0.403
1.641AsnAsn: 1.641 ± 0.499
3.282AsnPro: 3.282 ± 0.716
1.532AsnGln: 1.532 ± 0.496
3.173AsnArg: 3.173 ± 0.646
2.407AsnSer: 2.407 ± 0.733
2.844AsnThr: 2.844 ± 0.537
4.048AsnVal: 4.048 ± 0.905
0.875AsnTrp: 0.875 ± 0.433
2.188AsnTyr: 2.188 ± 0.679
0.0AsnXaa: 0.0 ± 0.0
Pro
6.783ProAla: 6.783 ± 1.387
0.656ProCys: 0.656 ± 0.258
3.72ProAsp: 3.72 ± 0.399
4.923ProGlu: 4.923 ± 0.685
2.626ProPhe: 2.626 ± 0.425
2.516ProGly: 2.516 ± 0.417
1.532ProHis: 1.532 ± 0.445
2.844ProIle: 2.844 ± 0.675
1.641ProLys: 1.641 ± 0.484
4.266ProLeu: 4.266 ± 0.709
1.313ProMet: 1.313 ± 0.534
3.173ProAsn: 3.173 ± 0.541
7.111ProPro: 7.111 ± 1.284
2.626ProGln: 2.626 ± 0.782
3.72ProArg: 3.72 ± 0.788
5.142ProSer: 5.142 ± 0.841
4.595ProThr: 4.595 ± 0.685
4.485ProVal: 4.485 ± 0.785
0.328ProTrp: 0.328 ± 0.166
2.516ProTyr: 2.516 ± 0.725
0.0ProXaa: 0.0 ± 0.0
Gln
2.844GlnAla: 2.844 ± 0.677
0.547GlnCys: 0.547 ± 0.192
1.86GlnAsp: 1.86 ± 0.427
2.188GlnGlu: 2.188 ± 0.559
1.313GlnPhe: 1.313 ± 0.474
1.969GlnGly: 1.969 ± 0.503
1.094GlnHis: 1.094 ± 0.491
1.532GlnIle: 1.532 ± 0.353
1.641GlnLys: 1.641 ± 0.35
4.376GlnLeu: 4.376 ± 0.579
1.313GlnMet: 1.313 ± 0.416
2.079GlnAsn: 2.079 ± 0.662
1.86GlnPro: 1.86 ± 0.463
2.297GlnGln: 2.297 ± 0.963
2.626GlnArg: 2.626 ± 0.764
1.969GlnSer: 1.969 ± 0.545
2.626GlnThr: 2.626 ± 0.727
2.188GlnVal: 2.188 ± 0.464
0.109GlnTrp: 0.109 ± 0.11
1.86GlnTyr: 1.86 ± 0.543
0.0GlnXaa: 0.0 ± 0.0
Arg
4.813ArgAla: 4.813 ± 0.779
0.985ArgCys: 0.985 ± 0.496
3.063ArgAsp: 3.063 ± 0.71
3.501ArgGlu: 3.501 ± 0.979
3.063ArgPhe: 3.063 ± 0.511
4.376ArgGly: 4.376 ± 0.949
2.626ArgHis: 2.626 ± 0.744
2.844ArgIle: 2.844 ± 0.675
3.501ArgLys: 3.501 ± 0.896
5.251ArgLeu: 5.251 ± 1.015
1.75ArgMet: 1.75 ± 0.37
3.063ArgAsn: 3.063 ± 0.997
4.048ArgPro: 4.048 ± 0.873
3.063ArgGln: 3.063 ± 0.515
8.642ArgArg: 8.642 ± 2.281
5.142ArgSer: 5.142 ± 0.809
3.173ArgThr: 3.173 ± 0.588
5.142ArgVal: 5.142 ± 0.612
0.875ArgTrp: 0.875 ± 0.283
2.407ArgTyr: 2.407 ± 0.511
0.0ArgXaa: 0.0 ± 0.0
Ser
5.579SerAla: 5.579 ± 0.92
1.313SerCys: 1.313 ± 0.354
5.36SerAsp: 5.36 ± 1.12
4.376SerGlu: 4.376 ± 0.693
2.844SerPhe: 2.844 ± 0.698
7.658SerGly: 7.658 ± 1.175
1.094SerHis: 1.094 ± 0.42
2.626SerIle: 2.626 ± 0.478
3.282SerLys: 3.282 ± 0.692
4.704SerLeu: 4.704 ± 0.818
1.313SerMet: 1.313 ± 0.45
2.407SerAsn: 2.407 ± 0.766
3.938SerPro: 3.938 ± 0.67
2.297SerGln: 2.297 ± 0.562
4.813SerArg: 4.813 ± 0.618
5.907SerSer: 5.907 ± 1.457
3.938SerThr: 3.938 ± 0.51
3.391SerVal: 3.391 ± 0.633
1.313SerTrp: 1.313 ± 0.381
1.86SerTyr: 1.86 ± 0.435
0.0SerXaa: 0.0 ± 0.0
Thr
7.001ThrAla: 7.001 ± 1.203
0.985ThrCys: 0.985 ± 0.337
2.735ThrAsp: 2.735 ± 0.695
3.829ThrGlu: 3.829 ± 0.501
2.844ThrPhe: 2.844 ± 0.491
4.485ThrGly: 4.485 ± 0.929
0.985ThrHis: 0.985 ± 0.463
2.516ThrIle: 2.516 ± 0.33
1.203ThrLys: 1.203 ± 0.358
4.813ThrLeu: 4.813 ± 0.952
0.875ThrMet: 0.875 ± 0.245
2.516ThrAsn: 2.516 ± 0.741
3.829ThrPro: 3.829 ± 0.785
2.407ThrGln: 2.407 ± 0.581
4.376ThrArg: 4.376 ± 0.691
4.157ThrSer: 4.157 ± 0.917
3.391ThrThr: 3.391 ± 0.67
5.032ThrVal: 5.032 ± 0.819
0.547ThrTrp: 0.547 ± 0.337
2.844ThrTyr: 2.844 ± 0.75
0.0ThrXaa: 0.0 ± 0.0
Val
4.923ValAla: 4.923 ± 0.99
1.422ValCys: 1.422 ± 0.365
4.048ValAsp: 4.048 ± 0.681
3.61ValGlu: 3.61 ± 0.681
3.063ValPhe: 3.063 ± 0.612
3.72ValGly: 3.72 ± 0.643
1.203ValHis: 1.203 ± 0.302
2.954ValIle: 2.954 ± 0.584
2.626ValLys: 2.626 ± 0.554
6.673ValLeu: 6.673 ± 0.54
1.094ValMet: 1.094 ± 0.436
2.516ValAsn: 2.516 ± 0.565
5.142ValPro: 5.142 ± 0.813
3.173ValGln: 3.173 ± 0.774
3.938ValArg: 3.938 ± 0.636
4.813ValSer: 4.813 ± 0.806
4.048ValThr: 4.048 ± 0.701
4.485ValVal: 4.485 ± 0.704
0.766ValTrp: 0.766 ± 0.307
2.626ValTyr: 2.626 ± 0.413
0.0ValXaa: 0.0 ± 0.0
Trp
0.766TrpAla: 0.766 ± 0.303
0.328TrpCys: 0.328 ± 0.165
0.766TrpAsp: 0.766 ± 0.235
0.656TrpGlu: 0.656 ± 0.151
0.219TrpPhe: 0.219 ± 0.158
0.766TrpGly: 0.766 ± 0.266
0.219TrpHis: 0.219 ± 0.162
0.547TrpIle: 0.547 ± 0.283
0.547TrpLys: 0.547 ± 0.3
0.766TrpLeu: 0.766 ± 0.201
0.109TrpMet: 0.109 ± 0.169
0.766TrpAsn: 0.766 ± 0.299
0.656TrpPro: 0.656 ± 0.515
0.766TrpGln: 0.766 ± 0.325
0.985TrpArg: 0.985 ± 0.327
1.094TrpSer: 1.094 ± 0.287
0.656TrpThr: 0.656 ± 0.289
1.203TrpVal: 1.203 ± 0.389
0.0TrpTrp: 0.0 ± 0.0
0.656TrpTyr: 0.656 ± 0.263
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.516TyrAla: 2.516 ± 0.333
0.985TyrCys: 0.985 ± 0.323
3.391TyrAsp: 3.391 ± 1.049
2.079TyrGlu: 2.079 ± 0.527
2.407TyrPhe: 2.407 ± 0.547
2.297TyrGly: 2.297 ± 0.546
1.203TyrHis: 1.203 ± 0.298
1.094TyrIle: 1.094 ± 0.358
1.641TyrLys: 1.641 ± 0.436
3.282TyrLeu: 3.282 ± 0.72
1.532TyrMet: 1.532 ± 0.52
1.422TyrAsn: 1.422 ± 0.472
2.626TyrPro: 2.626 ± 0.511
0.875TyrGln: 0.875 ± 0.192
2.735TyrArg: 2.735 ± 0.438
3.063TyrSer: 3.063 ± 0.619
1.75TyrThr: 1.75 ± 0.453
2.954TyrVal: 2.954 ± 0.559
0.656TyrTrp: 0.656 ± 0.297
1.203TyrTyr: 1.203 ± 0.18
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 19 proteins (9142 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski