Amino acid dipepetide frequency for Changjiang polero-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.281AlaAla: 3.281 ± 1.448
1.641AlaCys: 1.641 ± 1.375
2.461AlaAsp: 2.461 ± 1.039
2.461AlaGlu: 2.461 ± 1.237
0.0AlaPhe: 0.0 ± 0.0
7.383AlaGly: 7.383 ± 1.838
0.82AlaHis: 0.82 ± 0.687
3.281AlaIle: 3.281 ± 1.586
4.102AlaLys: 4.102 ± 1.604
8.203AlaLeu: 8.203 ± 1.216
0.0AlaMet: 0.0 ± 0.0
3.281AlaAsn: 3.281 ± 0.502
8.203AlaPro: 8.203 ± 2.507
1.641AlaGln: 1.641 ± 0.724
4.922AlaArg: 4.922 ± 2.129
8.203AlaSer: 8.203 ± 1.39
4.922AlaThr: 4.922 ± 2.764
5.742AlaVal: 5.742 ± 1.488
0.82AlaTrp: 0.82 ± 0.613
1.641AlaTyr: 1.641 ± 0.724
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.461CysAsp: 2.461 ± 1.226
0.82CysGlu: 0.82 ± 0.681
0.82CysPhe: 0.82 ± 0.687
1.641CysGly: 1.641 ± 0.724
0.0CysHis: 0.0 ± 0.0
0.82CysIle: 0.82 ± 0.687
0.0CysLys: 0.0 ± 0.0
0.82CysLeu: 0.82 ± 0.687
0.0CysMet: 0.0 ± 0.0
0.82CysAsn: 0.82 ± 0.613
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
3.281CysSer: 3.281 ± 0.758
0.82CysThr: 0.82 ± 0.681
0.82CysVal: 0.82 ± 0.613
0.82CysTrp: 0.82 ± 0.681
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.641AspAla: 1.641 ± 1.375
2.461AspCys: 2.461 ± 1.226
3.281AspAsp: 3.281 ± 1.448
4.102AspGlu: 4.102 ± 1.417
3.281AspPhe: 3.281 ± 1.846
6.563AspGly: 6.563 ± 0.562
0.82AspHis: 0.82 ± 0.613
2.461AspIle: 2.461 ± 1.039
0.82AspLys: 0.82 ± 0.681
2.461AspLeu: 2.461 ± 1.174
0.82AspMet: 0.82 ± 0.687
0.82AspAsn: 0.82 ± 0.681
4.102AspPro: 4.102 ± 1.443
0.82AspGln: 0.82 ± 0.687
0.82AspArg: 0.82 ± 0.613
5.742AspSer: 5.742 ± 1.93
3.281AspThr: 3.281 ± 1.448
2.461AspVal: 2.461 ± 0.111
0.82AspTrp: 0.82 ± 0.687
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.922GluAla: 4.922 ± 2.764
1.641GluCys: 1.641 ± 1.361
2.461GluAsp: 2.461 ± 1.158
3.281GluGlu: 3.281 ± 1.448
2.461GluPhe: 2.461 ± 2.062
4.102GluGly: 4.102 ± 0.586
0.82GluHis: 0.82 ± 0.681
2.461GluIle: 2.461 ± 1.226
4.922GluLys: 4.922 ± 2.078
3.281GluLeu: 3.281 ± 1.271
0.82GluMet: 0.82 ± 0.613
0.82GluAsn: 0.82 ± 0.687
3.281GluPro: 3.281 ± 1.271
4.102GluGln: 4.102 ± 1.907
1.641GluArg: 1.641 ± 1.361
1.641GluSer: 1.641 ± 0.724
4.922GluThr: 4.922 ± 2.764
4.102GluVal: 4.102 ± 2.526
2.461GluTrp: 2.461 ± 1.237
2.461GluTyr: 2.461 ± 1.226
0.0GluXaa: 0.0 ± 0.0
Phe
1.641PheAla: 1.641 ± 0.636
0.82PheCys: 0.82 ± 0.687
1.641PheAsp: 1.641 ± 0.636
1.641PheGlu: 1.641 ± 0.636
0.0PhePhe: 0.0 ± 0.0
3.281PheGly: 3.281 ± 0.502
0.82PheHis: 0.82 ± 0.681
0.82PheIle: 0.82 ± 0.687
3.281PheLys: 3.281 ± 0.74
2.461PheLeu: 2.461 ± 1.174
1.641PheMet: 1.641 ± 0.724
0.82PheAsn: 0.82 ± 0.681
0.0PhePro: 0.0 ± 0.0
2.461PheGln: 2.461 ± 1.042
1.641PheArg: 1.641 ± 1.361
4.102PheSer: 4.102 ± 1.115
1.641PheThr: 1.641 ± 0.629
4.102PheVal: 4.102 ± 1.907
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.922GlyAla: 4.922 ± 0.944
0.82GlyCys: 0.82 ± 0.681
0.82GlyAsp: 0.82 ± 0.687
6.563GlyGlu: 6.563 ± 1.523
5.742GlyPhe: 5.742 ± 1.239
6.563GlyGly: 6.563 ± 2.883
1.641GlyHis: 1.641 ± 0.724
1.641GlyIle: 1.641 ± 0.724
8.203GlyLys: 8.203 ± 3.145
6.563GlyLeu: 6.563 ± 0.6
0.82GlyMet: 0.82 ± 0.681
0.82GlyAsn: 0.82 ± 0.613
4.102GlyPro: 4.102 ± 2.168
1.641GlyGln: 1.641 ± 1.361
2.461GlyArg: 2.461 ± 1.042
8.203GlySer: 8.203 ± 2.834
4.102GlyThr: 4.102 ± 2.169
6.563GlyVal: 6.563 ± 2.921
2.461GlyTrp: 2.461 ± 0.111
3.281GlyTyr: 3.281 ± 0.502
0.0GlyXaa: 0.0 ± 0.0
His
1.641HisAla: 1.641 ± 0.629
0.82HisCys: 0.82 ± 0.687
1.641HisAsp: 1.641 ± 1.375
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.82HisGly: 0.82 ± 0.687
1.641HisHis: 1.641 ± 1.375
0.0HisIle: 0.0 ± 0.0
0.82HisLys: 0.82 ± 0.687
4.102HisLeu: 4.102 ± 1.907
0.0HisMet: 0.0 ± 0.0
1.641HisAsn: 1.641 ± 1.375
0.82HisPro: 0.82 ± 0.681
0.82HisGln: 0.82 ± 0.613
0.82HisArg: 0.82 ± 0.687
2.461HisSer: 2.461 ± 1.042
0.0HisThr: 0.0 ± 0.0
1.641HisVal: 1.641 ± 1.226
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.102IleAla: 4.102 ± 0.608
0.0IleCys: 0.0 ± 0.0
1.641IleAsp: 1.641 ± 1.361
3.281IleGlu: 3.281 ± 0.502
0.0IlePhe: 0.0 ± 0.0
2.461IleGly: 2.461 ± 1.226
0.82IleHis: 0.82 ± 0.687
0.82IleIle: 0.82 ± 0.613
0.0IleLys: 0.0 ± 0.0
3.281IleLeu: 3.281 ± 1.258
0.82IleMet: 0.82 ± 0.687
1.641IleAsn: 1.641 ± 0.629
6.563IlePro: 6.563 ± 0.562
4.922IleGln: 4.922 ± 1.887
2.461IleArg: 2.461 ± 1.174
4.102IleSer: 4.102 ± 0.586
0.82IleThr: 0.82 ± 0.681
1.641IleVal: 1.641 ± 0.629
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
5.742LysAla: 5.742 ± 3.365
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
4.102LysGlu: 4.102 ± 2.168
1.641LysPhe: 1.641 ± 0.629
1.641LysGly: 1.641 ± 0.724
0.82LysHis: 0.82 ± 0.613
0.82LysIle: 0.82 ± 0.681
2.461LysLys: 2.461 ± 1.039
4.922LysLeu: 4.922 ± 1.322
2.461LysMet: 2.461 ± 1.268
0.82LysAsn: 0.82 ± 0.681
2.461LysPro: 2.461 ± 0.111
4.102LysGln: 4.102 ± 1.115
2.461LysArg: 2.461 ± 1.174
9.024LysSer: 9.024 ± 2.541
0.82LysThr: 0.82 ± 0.681
4.102LysVal: 4.102 ± 1.614
3.281LysTrp: 3.281 ± 2.722
0.82LysTyr: 0.82 ± 0.613
0.0LysXaa: 0.0 ± 0.0
Leu
7.383LeuAla: 7.383 ± 2.368
2.461LeuCys: 2.461 ± 1.174
4.102LeuAsp: 4.102 ± 1.417
8.203LeuGlu: 8.203 ± 2.716
4.922LeuPhe: 4.922 ± 0.957
3.281LeuGly: 3.281 ± 1.448
2.461LeuHis: 2.461 ± 1.174
3.281LeuIle: 3.281 ± 1.271
4.102LeuLys: 4.102 ± 1.735
5.742LeuLeu: 5.742 ± 1.488
3.281LeuMet: 3.281 ± 1.586
3.281LeuAsn: 3.281 ± 0.502
5.742LeuPro: 5.742 ± 1.559
2.461LeuGln: 2.461 ± 1.237
4.102LeuArg: 4.102 ± 0.835
7.383LeuSer: 7.383 ± 0.334
9.844LeuThr: 9.844 ± 1.547
5.742LeuVal: 5.742 ± 1.855
1.641LeuTrp: 1.641 ± 0.636
4.102LeuTyr: 4.102 ± 0.608
0.0LeuXaa: 0.0 ± 0.0
Met
5.742MetAla: 5.742 ± 0.837
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.82MetGlu: 0.82 ± 0.687
0.82MetPhe: 0.82 ± 0.613
0.82MetGly: 0.82 ± 0.687
0.0MetHis: 0.0 ± 0.0
1.641MetIle: 1.641 ± 0.629
0.82MetLys: 0.82 ± 0.613
2.461MetLeu: 2.461 ± 1.174
0.0MetMet: 0.0 ± 0.0
0.82MetAsn: 0.82 ± 0.681
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
2.461MetSer: 2.461 ± 1.174
0.0MetThr: 0.0 ± 0.0
1.641MetVal: 1.641 ± 0.629
0.0MetTrp: 0.0 ± 0.0
0.82MetTyr: 0.82 ± 0.681
0.0MetXaa: 0.0 ± 0.0
Asn
0.82AsnAla: 0.82 ± 0.687
0.0AsnCys: 0.0 ± 0.0
2.461AsnAsp: 2.461 ± 1.226
1.641AsnGlu: 1.641 ± 0.636
4.102AsnPhe: 4.102 ± 0.835
3.281AsnGly: 3.281 ± 2.451
0.0AsnHis: 0.0 ± 0.0
0.82AsnIle: 0.82 ± 0.681
2.461AsnLys: 2.461 ± 1.174
1.641AsnLeu: 1.641 ± 0.636
0.82AsnMet: 0.82 ± 0.681
0.0AsnAsn: 0.0 ± 0.0
2.461AsnPro: 2.461 ± 1.226
1.641AsnGln: 1.641 ± 1.375
1.641AsnArg: 1.641 ± 0.724
4.922AsnSer: 4.922 ± 1.167
2.461AsnThr: 2.461 ± 0.111
1.641AsnVal: 1.641 ± 0.629
1.641AsnTrp: 1.641 ± 0.636
1.641AsnTyr: 1.641 ± 0.724
0.0AsnXaa: 0.0 ± 0.0
Pro
8.203ProAla: 8.203 ± 3.145
0.0ProCys: 0.0 ± 0.0
4.922ProAsp: 4.922 ± 2.172
3.281ProGlu: 3.281 ± 1.846
0.0ProPhe: 0.0 ± 0.0
5.742ProGly: 5.742 ± 2.221
1.641ProHis: 1.641 ± 1.375
2.461ProIle: 2.461 ± 0.111
1.641ProLys: 1.641 ± 1.226
3.281ProLeu: 3.281 ± 0.502
0.0ProMet: 0.0 ± 0.0
1.641ProAsn: 1.641 ± 0.629
5.742ProPro: 5.742 ± 2.339
4.102ProGln: 4.102 ± 1.115
6.563ProArg: 6.563 ± 2.516
8.203ProSer: 8.203 ± 1.85
4.922ProThr: 4.922 ± 1.727
6.563ProVal: 6.563 ± 1.545
0.0ProTrp: 0.0 ± 0.0
1.641ProTyr: 1.641 ± 0.724
0.0ProXaa: 0.0 ± 0.0
Gln
4.922GlnAla: 4.922 ± 1.167
0.0GlnCys: 0.0 ± 0.0
2.461GlnAsp: 2.461 ± 1.226
1.641GlnGlu: 1.641 ± 0.629
1.641GlnPhe: 1.641 ± 0.636
1.641GlnGly: 1.641 ± 0.629
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
2.461GlnLys: 2.461 ± 1.237
7.383GlnLeu: 7.383 ± 2.2
0.0GlnMet: 0.0 ± 0.0
3.281GlnAsn: 3.281 ± 1.816
4.102GlnPro: 4.102 ± 0.835
1.641GlnGln: 1.641 ± 0.629
3.281GlnArg: 3.281 ± 0.502
4.102GlnSer: 4.102 ± 1.115
0.82GlnThr: 0.82 ± 0.613
0.82GlnVal: 0.82 ± 0.613
0.82GlnTrp: 0.82 ± 0.613
0.82GlnTyr: 0.82 ± 0.613
0.0GlnXaa: 0.0 ± 0.0
Arg
0.82ArgAla: 0.82 ± 0.681
0.82ArgCys: 0.82 ± 0.613
0.82ArgAsp: 0.82 ± 0.681
0.82ArgGlu: 0.82 ± 0.687
0.82ArgPhe: 0.82 ± 0.687
6.563ArgGly: 6.563 ± 1.523
2.461ArgHis: 2.461 ± 2.062
2.461ArgIle: 2.461 ± 1.237
1.641ArgLys: 1.641 ± 1.226
8.203ArgLeu: 8.203 ± 2.886
0.82ArgMet: 0.82 ± 0.613
3.281ArgAsn: 3.281 ± 0.758
2.461ArgPro: 2.461 ± 1.158
0.0ArgGln: 0.0 ± 0.0
5.742ArgArg: 5.742 ± 1.48
2.461ArgSer: 2.461 ± 1.237
1.641ArgThr: 1.641 ± 1.226
7.383ArgVal: 7.383 ± 0.853
1.641ArgTrp: 1.641 ± 0.629
0.82ArgTyr: 0.82 ± 0.687
0.0ArgXaa: 0.0 ± 0.0
Ser
3.281SerAla: 3.281 ± 1.587
0.0SerCys: 0.0 ± 0.0
4.922SerAsp: 4.922 ± 0.223
9.024SerGlu: 9.024 ± 1.481
2.461SerPhe: 2.461 ± 1.158
11.485SerGly: 11.485 ± 2.731
1.641SerHis: 1.641 ± 0.636
7.383SerIle: 7.383 ± 2.954
5.742SerLys: 5.742 ± 1.239
10.664SerLeu: 10.664 ± 4.873
0.82SerMet: 0.82 ± 0.479
4.102SerAsn: 4.102 ± 1.907
6.563SerPro: 6.563 ± 2.516
4.102SerGln: 4.102 ± 1.115
4.102SerArg: 4.102 ± 0.835
5.742SerSer: 5.742 ± 0.81
4.922SerThr: 4.922 ± 0.223
6.563SerVal: 6.563 ± 3.132
2.461SerTrp: 2.461 ± 1.174
4.922SerTyr: 4.922 ± 1.167
0.0SerXaa: 0.0 ± 0.0
Thr
6.563ThrAla: 6.563 ± 1.523
0.82ThrCys: 0.82 ± 0.613
4.922ThrAsp: 4.922 ± 2.129
0.0ThrGlu: 0.0 ± 0.0
2.461ThrPhe: 2.461 ± 0.111
2.461ThrGly: 2.461 ± 1.158
0.82ThrHis: 0.82 ± 0.613
1.641ThrIle: 1.641 ± 1.226
2.461ThrLys: 2.461 ± 1.039
3.281ThrLeu: 3.281 ± 0.502
1.641ThrMet: 1.641 ± 1.851
4.102ThrAsn: 4.102 ± 1.417
6.563ThrPro: 6.563 ± 2.059
0.82ThrGln: 0.82 ± 0.681
0.82ThrArg: 0.82 ± 0.613
5.742ThrSer: 5.742 ± 2.615
7.383ThrThr: 7.383 ± 2.653
3.281ThrVal: 3.281 ± 1.586
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.742ValAla: 5.742 ± 1.239
1.641ValCys: 1.641 ± 1.361
4.102ValAsp: 4.102 ± 1.614
2.461ValGlu: 2.461 ± 1.174
1.641ValPhe: 1.641 ± 0.629
5.742ValGly: 5.742 ± 0.391
2.461ValHis: 2.461 ± 0.111
3.281ValIle: 3.281 ± 1.258
4.102ValLys: 4.102 ± 0.586
7.383ValLeu: 7.383 ± 2.99
0.0ValMet: 0.0 ± 0.0
2.461ValAsn: 2.461 ± 0.111
6.563ValPro: 6.563 ± 1.545
5.742ValGln: 5.742 ± 1.855
4.922ValArg: 4.922 ± 0.957
7.383ValSer: 7.383 ± 1.443
1.641ValThr: 1.641 ± 0.636
3.281ValVal: 3.281 ± 1.587
0.82ValTrp: 0.82 ± 0.687
1.641ValTyr: 1.641 ± 0.629
0.0ValXaa: 0.0 ± 0.0
Trp
1.641TrpAla: 1.641 ± 0.724
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.641TrpGlu: 1.641 ± 0.629
0.0TrpPhe: 0.0 ± 0.0
0.82TrpGly: 0.82 ± 0.681
0.0TrpHis: 0.0 ± 0.0
0.82TrpIle: 0.82 ± 0.687
0.0TrpLys: 0.0 ± 0.0
4.102TrpLeu: 4.102 ± 1.417
1.641TrpMet: 1.641 ± 0.636
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.82TrpGln: 0.82 ± 0.613
2.461TrpArg: 2.461 ± 1.174
3.281TrpSer: 3.281 ± 0.74
0.82TrpThr: 0.82 ± 0.687
1.641TrpVal: 1.641 ± 0.636
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
2.461TyrAsp: 2.461 ± 0.111
0.82TyrGlu: 0.82 ± 0.687
0.0TyrPhe: 0.0 ± 0.0
1.641TyrGly: 1.641 ± 0.636
0.0TyrHis: 0.0 ± 0.0
2.461TyrIle: 2.461 ± 1.226
2.461TyrLys: 2.461 ± 1.237
3.281TyrLeu: 3.281 ± 0.74
1.641TyrMet: 1.641 ± 0.629
1.641TyrAsn: 1.641 ± 0.636
0.82TyrPro: 0.82 ± 0.681
0.0TyrGln: 0.0 ± 0.0
0.82TyrArg: 0.82 ± 0.687
2.461TyrSer: 2.461 ± 1.158
0.82TyrThr: 0.82 ± 0.613
3.281TyrVal: 3.281 ± 1.258
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1220 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski