Amino acid dipepetide frequency for Rotavirus A turkey-tc/GER/03V0002E10/2003/G22P[35]

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.678AlaAla: 4.678 ± 0.667
0.835AlaCys: 0.835 ± 0.292
3.174AlaAsp: 3.174 ± 0.552
2.673AlaGlu: 2.673 ± 0.615
1.838AlaPhe: 1.838 ± 0.314
1.838AlaGly: 1.838 ± 0.426
0.835AlaHis: 0.835 ± 0.365
3.842AlaIle: 3.842 ± 1.105
4.511AlaLys: 4.511 ± 1.212
4.176AlaLeu: 4.176 ± 0.991
2.172AlaMet: 2.172 ± 0.387
5.346AlaAsn: 5.346 ± 0.613
1.671AlaPro: 1.671 ± 0.766
1.838AlaGln: 1.838 ± 0.588
2.673AlaArg: 2.673 ± 0.99
4.009AlaSer: 4.009 ± 0.98
2.84AlaThr: 2.84 ± 0.704
3.675AlaVal: 3.675 ± 0.476
0.0AlaTrp: 0.0 ± 0.0
1.671AlaTyr: 1.671 ± 0.439
0.0AlaXaa: 0.0 ± 0.0
Cys
0.668CysAla: 0.668 ± 0.371
0.501CysCys: 0.501 ± 0.318
0.835CysAsp: 0.835 ± 0.277
0.668CysGlu: 0.668 ± 0.347
1.002CysPhe: 1.002 ± 0.5
0.334CysGly: 0.334 ± 0.218
0.0CysHis: 0.0 ± 0.0
0.835CysIle: 0.835 ± 0.354
0.668CysLys: 0.668 ± 0.316
0.501CysLeu: 0.501 ± 0.526
0.835CysMet: 0.835 ± 0.382
1.169CysAsn: 1.169 ± 0.617
0.668CysPro: 0.668 ± 0.485
0.668CysGln: 0.668 ± 0.316
1.169CysArg: 1.169 ± 0.69
0.167CysSer: 0.167 ± 0.14
1.002CysThr: 1.002 ± 0.515
0.668CysVal: 0.668 ± 0.288
0.167CysTrp: 0.167 ± 0.154
1.002CysTyr: 1.002 ± 0.26
0.0CysXaa: 0.0 ± 0.0
Asp
3.174AspAla: 3.174 ± 0.822
0.835AspCys: 0.835 ± 0.387
4.845AspAsp: 4.845 ± 0.831
3.174AspGlu: 3.174 ± 0.682
4.009AspPhe: 4.009 ± 0.612
2.673AspGly: 2.673 ± 0.595
0.501AspHis: 0.501 ± 0.287
5.179AspIle: 5.179 ± 0.736
3.508AspLys: 3.508 ± 0.861
5.179AspLeu: 5.179 ± 1.027
1.838AspMet: 1.838 ± 0.575
2.673AspAsn: 2.673 ± 0.66
2.339AspPro: 2.339 ± 0.614
3.007AspGln: 3.007 ± 0.664
2.005AspArg: 2.005 ± 0.41
4.845AspSer: 4.845 ± 0.711
2.673AspThr: 2.673 ± 0.615
6.181AspVal: 6.181 ± 0.921
0.334AspTrp: 0.334 ± 0.24
4.176AspTyr: 4.176 ± 0.76
0.0AspXaa: 0.0 ± 0.0
Glu
1.838GluAla: 1.838 ± 0.577
0.501GluCys: 0.501 ± 0.294
2.506GluAsp: 2.506 ± 0.965
2.84GluGlu: 2.84 ± 0.679
3.007GluPhe: 3.007 ± 0.719
1.169GluGly: 1.169 ± 0.446
1.002GluHis: 1.002 ± 0.352
3.508GluIle: 3.508 ± 0.674
4.845GluLys: 4.845 ± 1.035
6.181GluLeu: 6.181 ± 0.991
1.838GluMet: 1.838 ± 0.393
2.84GluAsn: 2.84 ± 0.652
1.504GluPro: 1.504 ± 0.484
2.005GluGln: 2.005 ± 1.004
2.339GluArg: 2.339 ± 0.756
4.176GluSer: 4.176 ± 1.113
3.007GluThr: 3.007 ± 0.744
2.84GluVal: 2.84 ± 0.587
1.002GluTrp: 1.002 ± 0.486
4.511GluTyr: 4.511 ± 0.717
0.0GluXaa: 0.0 ± 0.0
Phe
2.172PheAla: 2.172 ± 0.723
1.002PheCys: 1.002 ± 0.488
3.508PheAsp: 3.508 ± 0.873
2.506PheGlu: 2.506 ± 0.846
0.668PhePhe: 0.668 ± 0.272
1.671PheGly: 1.671 ± 0.325
1.504PheHis: 1.504 ± 0.457
3.174PheIle: 3.174 ± 0.76
4.009PheLys: 4.009 ± 0.771
2.673PheLeu: 2.673 ± 0.519
0.668PheMet: 0.668 ± 0.267
3.174PheAsn: 3.174 ± 0.556
1.336PhePro: 1.336 ± 0.589
1.504PheGln: 1.504 ± 0.513
2.005PheArg: 2.005 ± 0.487
3.174PheSer: 3.174 ± 1.036
2.005PheThr: 2.005 ± 0.548
2.506PheVal: 2.506 ± 0.57
0.334PheTrp: 0.334 ± 0.189
1.336PheTyr: 1.336 ± 0.535
0.0PheXaa: 0.0 ± 0.0
Gly
1.169GlyAla: 1.169 ± 0.422
0.334GlyCys: 0.334 ± 0.26
1.838GlyAsp: 1.838 ± 0.421
1.169GlyGlu: 1.169 ± 0.413
1.002GlyPhe: 1.002 ± 0.453
2.005GlyGly: 2.005 ± 0.728
0.668GlyHis: 0.668 ± 0.345
3.675GlyIle: 3.675 ± 0.478
2.84GlyLys: 2.84 ± 0.684
3.341GlyLeu: 3.341 ± 0.61
0.501GlyMet: 0.501 ± 0.525
2.506GlyAsn: 2.506 ± 0.821
1.002GlyPro: 1.002 ± 0.461
1.336GlyGln: 1.336 ± 0.369
1.002GlyArg: 1.002 ± 0.308
2.172GlySer: 2.172 ± 0.593
1.838GlyThr: 1.838 ± 0.752
2.673GlyVal: 2.673 ± 0.508
0.334GlyTrp: 0.334 ± 0.253
1.838GlyTyr: 1.838 ± 0.603
0.0GlyXaa: 0.0 ± 0.0
His
1.336HisAla: 1.336 ± 0.499
0.167HisCys: 0.167 ± 0.186
2.005HisAsp: 2.005 ± 0.584
0.501HisGlu: 0.501 ± 0.211
0.668HisPhe: 0.668 ± 0.335
0.334HisGly: 0.334 ± 0.221
0.334HisHis: 0.334 ± 0.255
1.002HisIle: 1.002 ± 0.343
1.002HisLys: 1.002 ± 0.435
1.671HisLeu: 1.671 ± 0.581
0.167HisMet: 0.167 ± 0.14
1.504HisAsn: 1.504 ± 0.496
0.501HisPro: 0.501 ± 0.211
0.334HisGln: 0.334 ± 0.213
0.668HisArg: 0.668 ± 0.27
0.501HisSer: 0.501 ± 0.288
1.002HisThr: 1.002 ± 0.433
1.002HisVal: 1.002 ± 0.313
0.0HisTrp: 0.0 ± 0.0
1.002HisTyr: 1.002 ± 0.372
0.0HisXaa: 0.0 ± 0.0
Ile
5.847IleAla: 5.847 ± 0.634
1.169IleCys: 1.169 ± 0.525
5.847IleAsp: 5.847 ± 0.822
4.678IleGlu: 4.678 ± 0.899
2.506IlePhe: 2.506 ± 0.559
2.506IleGly: 2.506 ± 0.713
0.835IleHis: 0.835 ± 0.284
4.845IleIle: 4.845 ± 1.008
4.678IleLys: 4.678 ± 0.959
7.183IleLeu: 7.183 ± 0.758
1.336IleMet: 1.336 ± 0.43
6.515IleAsn: 6.515 ± 1.046
2.506IlePro: 2.506 ± 0.93
3.341IleGln: 3.341 ± 0.626
3.341IleArg: 3.341 ± 0.787
5.179IleSer: 5.179 ± 1.377
5.847IleThr: 5.847 ± 0.631
5.012IleVal: 5.012 ± 0.998
0.501IleTrp: 0.501 ± 0.266
3.508IleTyr: 3.508 ± 0.629
0.0IleXaa: 0.0 ± 0.0
Lys
2.339LysAla: 2.339 ± 0.6
0.501LysCys: 0.501 ± 0.249
4.009LysAsp: 4.009 ± 0.528
3.508LysGlu: 3.508 ± 0.767
2.84LysPhe: 2.84 ± 0.7
2.005LysGly: 2.005 ± 0.492
0.501LysHis: 0.501 ± 0.242
6.515LysIle: 6.515 ± 1.144
4.009LysLys: 4.009 ± 1.066
6.849LysLeu: 6.849 ± 1.373
3.007LysMet: 3.007 ± 0.62
2.673LysAsn: 2.673 ± 0.545
1.838LysPro: 1.838 ± 0.474
2.84LysGln: 2.84 ± 0.649
3.341LysArg: 3.341 ± 0.707
6.348LysSer: 6.348 ± 2.197
4.343LysThr: 4.343 ± 0.597
4.176LysVal: 4.176 ± 0.838
1.169LysTrp: 1.169 ± 0.598
4.511LysTyr: 4.511 ± 0.902
0.0LysXaa: 0.0 ± 0.0
Leu
4.678LeuAla: 4.678 ± 0.925
1.169LeuCys: 1.169 ± 0.785
5.68LeuAsp: 5.68 ± 0.768
3.174LeuGlu: 3.174 ± 0.603
3.174LeuPhe: 3.174 ± 0.671
2.172LeuGly: 2.172 ± 0.54
1.838LeuHis: 1.838 ± 0.594
6.515LeuIle: 6.515 ± 0.88
5.179LeuLys: 5.179 ± 1.231
8.353LeuLeu: 8.353 ± 1.017
2.506LeuMet: 2.506 ± 0.651
7.35LeuAsn: 7.35 ± 1.137
4.678LeuPro: 4.678 ± 0.883
4.678LeuGln: 4.678 ± 0.933
5.012LeuArg: 5.012 ± 0.627
8.186LeuSer: 8.186 ± 1.231
6.014LeuThr: 6.014 ± 1.126
6.515LeuVal: 6.515 ± 1.0
0.668LeuTrp: 0.668 ± 0.317
4.845LeuTyr: 4.845 ± 1.036
0.0LeuXaa: 0.0 ± 0.0
Met
1.671MetAla: 1.671 ± 0.299
0.167MetCys: 0.167 ± 0.14
1.336MetAsp: 1.336 ± 0.383
0.835MetGlu: 0.835 ± 0.295
1.504MetPhe: 1.504 ± 0.517
1.002MetGly: 1.002 ± 0.372
0.835MetHis: 0.835 ± 0.294
1.169MetIle: 1.169 ± 0.377
2.84MetLys: 2.84 ± 0.923
3.675MetLeu: 3.675 ± 0.775
0.334MetMet: 0.334 ± 0.297
2.172MetAsn: 2.172 ± 0.366
0.835MetPro: 0.835 ± 0.299
1.671MetGln: 1.671 ± 0.54
1.336MetArg: 1.336 ± 0.477
2.172MetSer: 2.172 ± 0.745
1.504MetThr: 1.504 ± 0.543
0.835MetVal: 0.835 ± 0.509
0.501MetTrp: 0.501 ± 0.223
1.002MetTyr: 1.002 ± 0.381
0.0MetXaa: 0.0 ± 0.0
Asn
4.343AsnAla: 4.343 ± 0.804
1.002AsnCys: 1.002 ± 0.684
4.678AsnAsp: 4.678 ± 0.691
3.174AsnGlu: 3.174 ± 0.797
2.172AsnPhe: 2.172 ± 0.57
2.84AsnGly: 2.84 ± 0.781
1.838AsnHis: 1.838 ± 0.541
3.174AsnIle: 3.174 ± 0.936
3.508AsnLys: 3.508 ± 1.025
6.849AsnLeu: 6.849 ± 0.993
2.005AsnMet: 2.005 ± 0.496
4.176AsnAsn: 4.176 ± 0.906
1.671AsnPro: 1.671 ± 0.524
3.675AsnGln: 3.675 ± 0.876
3.007AsnArg: 3.007 ± 0.88
5.513AsnSer: 5.513 ± 0.947
3.675AsnThr: 3.675 ± 0.588
4.343AsnVal: 4.343 ± 0.772
1.671AsnTrp: 1.671 ± 0.573
4.678AsnTyr: 4.678 ± 0.953
0.0AsnXaa: 0.0 ± 0.0
Pro
1.336ProAla: 1.336 ± 0.472
0.167ProCys: 0.167 ± 0.164
1.169ProAsp: 1.169 ± 0.575
2.005ProGlu: 2.005 ± 0.491
2.005ProPhe: 2.005 ± 0.406
1.169ProGly: 1.169 ± 0.417
0.501ProHis: 0.501 ± 0.288
3.508ProIle: 3.508 ± 0.823
2.005ProLys: 2.005 ± 0.398
1.504ProLeu: 1.504 ± 0.473
1.169ProMet: 1.169 ± 0.408
2.339ProAsn: 2.339 ± 0.945
1.336ProPro: 1.336 ± 0.494
1.169ProGln: 1.169 ± 0.287
1.169ProArg: 1.169 ± 0.27
2.339ProSer: 2.339 ± 0.635
2.84ProThr: 2.84 ± 0.431
2.005ProVal: 2.005 ± 0.637
0.0ProTrp: 0.0 ± 0.0
2.339ProTyr: 2.339 ± 0.674
0.0ProXaa: 0.0 ± 0.0
Gln
1.504GlnAla: 1.504 ± 0.578
0.334GlnCys: 0.334 ± 0.174
2.339GlnAsp: 2.339 ± 0.622
2.339GlnGlu: 2.339 ± 0.805
1.336GlnPhe: 1.336 ± 0.567
1.002GlnGly: 1.002 ± 0.311
0.501GlnHis: 0.501 ± 0.287
3.842GlnIle: 3.842 ± 1.321
2.84GlnLys: 2.84 ± 0.494
5.68GlnLeu: 5.68 ± 0.961
1.002GlnMet: 1.002 ± 0.577
2.506GlnAsn: 2.506 ± 0.553
1.169GlnPro: 1.169 ± 0.433
2.005GlnGln: 2.005 ± 0.731
2.84GlnArg: 2.84 ± 0.858
1.838GlnSer: 1.838 ± 0.351
3.675GlnThr: 3.675 ± 1.433
3.341GlnVal: 3.341 ± 1.103
0.668GlnTrp: 0.668 ± 0.272
2.673GlnTyr: 2.673 ± 0.709
0.0GlnXaa: 0.0 ± 0.0
Arg
2.339ArgAla: 2.339 ± 0.558
1.002ArgCys: 1.002 ± 0.405
1.838ArgAsp: 1.838 ± 0.43
3.675ArgGlu: 3.675 ± 0.345
2.506ArgPhe: 2.506 ± 0.604
2.005ArgGly: 2.005 ± 0.434
0.835ArgHis: 0.835 ± 0.319
3.508ArgIle: 3.508 ± 0.652
3.007ArgLys: 3.007 ± 0.848
4.343ArgLeu: 4.343 ± 0.818
1.336ArgMet: 1.336 ± 0.465
3.007ArgAsn: 3.007 ± 0.825
0.835ArgPro: 0.835 ± 0.373
2.506ArgGln: 2.506 ± 0.7
2.84ArgArg: 2.84 ± 0.925
4.511ArgSer: 4.511 ± 0.931
1.838ArgThr: 1.838 ± 0.449
3.007ArgVal: 3.007 ± 0.53
0.668ArgTrp: 0.668 ± 0.278
2.005ArgTyr: 2.005 ± 0.554
0.0ArgXaa: 0.0 ± 0.0
Ser
3.842SerAla: 3.842 ± 1.358
1.336SerCys: 1.336 ± 0.601
4.511SerAsp: 4.511 ± 1.069
5.346SerGlu: 5.346 ± 1.426
2.673SerPhe: 2.673 ± 0.554
2.339SerGly: 2.339 ± 0.588
1.002SerHis: 1.002 ± 0.491
6.181SerIle: 6.181 ± 0.744
5.68SerLys: 5.68 ± 0.759
7.183SerLeu: 7.183 ± 0.867
1.838SerMet: 1.838 ± 0.354
5.68SerAsn: 5.68 ± 1.123
1.169SerPro: 1.169 ± 0.291
3.174SerGln: 3.174 ± 0.639
3.842SerArg: 3.842 ± 0.987
6.181SerSer: 6.181 ± 1.929
5.179SerThr: 5.179 ± 1.128
5.68SerVal: 5.68 ± 0.849
0.501SerTrp: 0.501 ± 0.348
3.174SerTyr: 3.174 ± 0.904
0.0SerXaa: 0.0 ± 0.0
Thr
2.172ThrAla: 2.172 ± 0.537
1.336ThrCys: 1.336 ± 0.679
4.678ThrAsp: 4.678 ± 0.9
3.007ThrGlu: 3.007 ± 0.584
3.007ThrPhe: 3.007 ± 0.43
2.339ThrGly: 2.339 ± 0.621
0.835ThrHis: 0.835 ± 0.213
5.68ThrIle: 5.68 ± 1.115
3.842ThrLys: 3.842 ± 0.655
6.849ThrLeu: 6.849 ± 0.924
1.336ThrMet: 1.336 ± 0.445
3.007ThrAsn: 3.007 ± 0.695
1.671ThrPro: 1.671 ± 0.343
3.007ThrGln: 3.007 ± 0.767
2.673ThrArg: 2.673 ± 0.399
4.678ThrSer: 4.678 ± 1.112
6.014ThrThr: 6.014 ± 0.841
4.845ThrVal: 4.845 ± 1.048
0.501ThrTrp: 0.501 ± 0.234
2.005ThrTyr: 2.005 ± 0.708
0.0ThrXaa: 0.0 ± 0.0
Val
5.847ValAla: 5.847 ± 0.752
0.668ValCys: 0.668 ± 0.488
4.511ValAsp: 4.511 ± 0.533
4.343ValGlu: 4.343 ± 0.702
2.339ValPhe: 2.339 ± 0.502
2.005ValGly: 2.005 ± 0.437
0.668ValHis: 0.668 ± 0.461
6.014ValIle: 6.014 ± 0.85
3.675ValLys: 3.675 ± 0.804
5.68ValLeu: 5.68 ± 0.615
1.169ValMet: 1.169 ± 0.431
4.343ValAsn: 4.343 ± 0.862
3.341ValPro: 3.341 ± 0.494
2.673ValGln: 2.673 ± 0.624
2.673ValArg: 2.673 ± 0.623
5.346ValSer: 5.346 ± 0.941
4.009ValThr: 4.009 ± 1.165
3.341ValVal: 3.341 ± 1.054
0.835ValTrp: 0.835 ± 0.489
3.007ValTyr: 3.007 ± 0.846
0.0ValXaa: 0.0 ± 0.0
Trp
0.334TrpAla: 0.334 ± 0.211
0.0TrpCys: 0.0 ± 0.0
0.835TrpAsp: 0.835 ± 0.24
0.0TrpGlu: 0.0 ± 0.0
0.167TrpPhe: 0.167 ± 0.137
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.336TrpIle: 1.336 ± 0.343
1.671TrpLys: 1.671 ± 0.558
1.504TrpLeu: 1.504 ± 0.48
0.668TrpMet: 0.668 ± 0.394
0.334TrpAsn: 0.334 ± 0.217
0.668TrpPro: 0.668 ± 0.428
0.334TrpGln: 0.334 ± 0.279
0.835TrpArg: 0.835 ± 0.425
0.668TrpSer: 0.668 ± 0.317
0.668TrpThr: 0.668 ± 0.378
0.501TrpVal: 0.501 ± 0.26
0.167TrpTrp: 0.167 ± 0.236
0.167TrpTyr: 0.167 ± 0.136
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.007TyrAla: 3.007 ± 0.912
0.501TyrCys: 0.501 ± 0.342
3.007TyrAsp: 3.007 ± 0.931
3.842TyrGlu: 3.842 ± 0.804
2.506TyrPhe: 2.506 ± 0.547
2.005TyrGly: 2.005 ± 0.891
0.668TyrHis: 0.668 ± 0.365
3.675TyrIle: 3.675 ± 0.945
3.007TyrLys: 3.007 ± 0.749
3.007TyrLeu: 3.007 ± 0.965
1.504TyrMet: 1.504 ± 0.607
4.678TyrAsn: 4.678 ± 0.572
1.336TyrPro: 1.336 ± 0.418
1.671TyrGln: 1.671 ± 0.483
2.84TyrArg: 2.84 ± 0.775
4.511TyrSer: 4.511 ± 1.318
3.508TyrThr: 3.508 ± 0.78
3.341TyrVal: 3.341 ± 0.746
0.835TyrTrp: 0.835 ± 0.34
3.508TyrTyr: 3.508 ± 1.278
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (5987 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski