Amino acid dipepetide frequency for Stenotrophomonas panacihumi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.454AlaAla: 18.454 ± 0.22	1.171AlaCys: 1.171 ± 0.037	7.331AlaAsp: 7.331 ± 0.087	7.061AlaGlu: 7.061 ± 0.092	4.107AlaPhe: 4.107 ± 0.069	11.607AlaGly: 11.607 ± 0.138	2.711AlaHis: 2.711 ± 0.054	5.073AlaIle: 5.073 ± 0.08	3.363AlaLys: 3.363 ± 0.083	15.703AlaLeu: 15.703 ± 0.158	3.394AlaMet: 3.394 ± 0.054	2.989AlaAsn: 2.989 ± 0.078	7.047AlaPro: 7.047 ± 0.114	6.164AlaGln: 6.164 ± 0.089	10.117AlaArg: 10.117 ± 0.131	6.472AlaSer: 6.472 ± 0.106	6.39AlaThr: 6.39 ± 0.103	8.808AlaVal: 8.808 ± 0.128	2.243AlaTrp: 2.243 ± 0.061	2.654AlaTyr: 2.654 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.975CysAla: 0.975 ± 0.031	0.086CysCys: 0.086 ± 0.008	0.429CysAsp: 0.429 ± 0.022	0.389CysGlu: 0.389 ± 0.018	0.261CysPhe: 0.261 ± 0.015	0.831CysGly: 0.831 ± 0.033	0.216CysHis: 0.216 ± 0.014	0.312CysIle: 0.312 ± 0.016	0.165CysLys: 0.165 ± 0.012	0.762CysLeu: 0.762 ± 0.028	0.126CysMet: 0.126 ± 0.011	0.179CysAsn: 0.179 ± 0.015	0.359CysPro: 0.359 ± 0.021	0.231CysGln: 0.231 ± 0.014	0.534CysArg: 0.534 ± 0.023	0.376CysSer: 0.376 ± 0.021	0.385CysThr: 0.385 ± 0.019	0.62CysVal: 0.62 ± 0.023	0.115CysTrp: 0.115 ± 0.01	0.173CysTyr: 0.173 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	8.688AspAla: 8.688 ± 0.107	0.396AspCys: 0.396 ± 0.02	3.315AspAsp: 3.315 ± 0.059	3.242AspGlu: 3.242 ± 0.064	2.131AspPhe: 2.131 ± 0.041	5.638AspGly: 5.638 ± 0.095	1.206AspHis: 1.206 ± 0.037	2.397AspIle: 2.397 ± 0.047	1.569AspLys: 1.569 ± 0.042	5.589AspLeu: 5.589 ± 0.085	1.075AspMet: 1.075 ± 0.032	1.434AspAsn: 1.434 ± 0.051	3.447AspPro: 3.447 ± 0.055	1.715AspGln: 1.715 ± 0.042	3.776AspArg: 3.776 ± 0.067	2.406AspSer: 2.406 ± 0.049	2.956AspThr: 2.956 ± 0.06	4.168AspVal: 4.168 ± 0.065	1.132AspTrp: 1.132 ± 0.035	1.76AspTyr: 1.76 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	7.288GluAla: 7.288 ± 0.096	0.298GluCys: 0.298 ± 0.02	2.67GluAsp: 2.67 ± 0.051	2.604GluGlu: 2.604 ± 0.061	1.652GluPhe: 1.652 ± 0.04	4.49GluGly: 4.49 ± 0.069	1.364GluHis: 1.364 ± 0.038	2.396GluIle: 2.396 ± 0.055	1.52GluLys: 1.52 ± 0.045	5.889GluLeu: 5.889 ± 0.092	1.071GluMet: 1.071 ± 0.035	1.172GluAsn: 1.172 ± 0.035	2.347GluPro: 2.347 ± 0.049	2.762GluGln: 2.762 ± 0.052	5.06GluArg: 5.06 ± 0.087	2.457GluSer: 2.457 ± 0.049	2.376GluThr: 2.376 ± 0.049	4.033GluVal: 4.033 ± 0.063	0.769GluTrp: 0.769 ± 0.027	1.193GluTyr: 1.193 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	4.311PheAla: 4.311 ± 0.071	0.309PheCys: 0.309 ± 0.017	2.674PheAsp: 2.674 ± 0.051	1.918PheGlu: 1.918 ± 0.046	1.209PhePhe: 1.209 ± 0.04	3.447PheGly: 3.447 ± 0.071	0.747PheHis: 0.747 ± 0.026	1.192PheIle: 1.192 ± 0.035	0.877PheLys: 0.877 ± 0.027	3.003PheLeu: 3.003 ± 0.07	0.607PheMet: 0.607 ± 0.024	1.088PheAsn: 1.088 ± 0.03	1.443PhePro: 1.443 ± 0.037	1.08PheGln: 1.08 ± 0.029	2.086PheArg: 2.086 ± 0.048	1.902PheSer: 1.902 ± 0.039	1.697PheThr: 1.697 ± 0.042	2.599PheVal: 2.599 ± 0.057	0.525PheTrp: 0.525 ± 0.025	0.885PheTyr: 0.885 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	9.551GlyAla: 9.551 ± 0.14	0.717GlyCys: 0.717 ± 0.029	4.822GlyAsp: 4.822 ± 0.085	5.329GlyGlu: 5.329 ± 0.073	3.373GlyPhe: 3.373 ± 0.059	7.545GlyGly: 7.545 ± 0.139	2.179GlyHis: 2.179 ± 0.048	3.831GlyIle: 3.831 ± 0.057	3.025GlyLys: 3.025 ± 0.071	9.008GlyLeu: 9.008 ± 0.112	2.275GlyMet: 2.275 ± 0.045	2.424GlyAsn: 2.424 ± 0.075	3.104GlyPro: 3.104 ± 0.054	3.741GlyGln: 3.741 ± 0.059	6.114GlyArg: 6.114 ± 0.088	4.632GlySer: 4.632 ± 0.094	4.634GlyThr: 4.634 ± 0.102	6.787GlyVal: 6.787 ± 0.097	1.829GlyTrp: 1.829 ± 0.048	2.47GlyTyr: 2.47 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	3.202HisAla: 3.202 ± 0.058	0.233HisCys: 0.233 ± 0.014	1.423HisAsp: 1.423 ± 0.032	1.168HisGlu: 1.168 ± 0.036	0.849HisPhe: 0.849 ± 0.03	2.312HisGly: 2.312 ± 0.047	0.602HisHis: 0.602 ± 0.026	0.714HisIle: 0.714 ± 0.025	0.442HisLys: 0.442 ± 0.021	2.241HisLeu: 2.241 ± 0.055	0.404HisMet: 0.404 ± 0.018	0.46HisAsn: 0.46 ± 0.019	1.475HisPro: 1.475 ± 0.038	0.669HisGln: 0.669 ± 0.025	1.618HisArg: 1.618 ± 0.041	0.914HisSer: 0.914 ± 0.03	0.87HisThr: 0.87 ± 0.032	1.659HisVal: 1.659 ± 0.041	0.483HisTrp: 0.483 ± 0.022	0.686HisTyr: 0.686 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.184IleAla: 6.184 ± 0.075	0.303IleCys: 0.303 ± 0.016	3.133IleAsp: 3.133 ± 0.056	2.816IleGlu: 2.816 ± 0.056	1.025IlePhe: 1.025 ± 0.03	4.277IleGly: 4.277 ± 0.085	0.789IleHis: 0.789 ± 0.026	1.214IleIle: 1.214 ± 0.035	1.032IleLys: 1.032 ± 0.041	2.839IleLeu: 2.839 ± 0.055	0.482IleMet: 0.482 ± 0.022	1.207IleAsn: 1.207 ± 0.042	1.958IlePro: 1.958 ± 0.045	1.098IleGln: 1.098 ± 0.036	2.391IleArg: 2.391 ± 0.046	2.053IleSer: 2.053 ± 0.049	2.151IleThr: 2.151 ± 0.051	3.084IleVal: 3.084 ± 0.06	0.416IleTrp: 0.416 ± 0.021	0.814IleTyr: 0.814 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	3.219LysAla: 3.219 ± 0.061	0.11LysCys: 0.11 ± 0.011	1.376LysAsp: 1.376 ± 0.05	1.114LysGlu: 1.114 ± 0.037	0.763LysPhe: 0.763 ± 0.029	2.024LysGly: 2.024 ± 0.056	0.549LysHis: 0.549 ± 0.025	1.156LysIle: 1.156 ± 0.041	0.932LysLys: 0.932 ± 0.051	2.966LysLeu: 2.966 ± 0.058	0.567LysMet: 0.567 ± 0.028	0.613LysAsn: 0.613 ± 0.031	1.842LysPro: 1.842 ± 0.049	1.262LysGln: 1.262 ± 0.045	1.967LysArg: 1.967 ± 0.042	1.27LysSer: 1.27 ± 0.035	1.387LysThr: 1.387 ± 0.044	2.132LysVal: 2.132 ± 0.051	0.307LysTrp: 0.307 ± 0.017	0.642LysTyr: 0.642 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	15.544LeuAla: 15.544 ± 0.157	0.952LeuCys: 0.952 ± 0.033	6.698LeuAsp: 6.698 ± 0.099	5.249LeuGlu: 5.249 ± 0.086	3.431LeuPhe: 3.431 ± 0.067	9.12LeuGly: 9.12 ± 0.106	2.436LeuHis: 2.436 ± 0.048	3.632LeuIle: 3.632 ± 0.067	2.842LeuLys: 2.842 ± 0.059	11.928LeuLeu: 11.928 ± 0.172	2.076LeuMet: 2.076 ± 0.039	2.244LeuAsn: 2.244 ± 0.048	6.786LeuPro: 6.786 ± 0.085	4.208LeuGln: 4.208 ± 0.065	9.2LeuArg: 9.2 ± 0.136	5.937LeuSer: 5.937 ± 0.083	4.671LeuThr: 4.671 ± 0.071	7.909LeuVal: 7.909 ± 0.094	1.495LeuTrp: 1.495 ± 0.045	2.299LeuTyr: 2.299 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	2.733MetAla: 2.733 ± 0.046	0.139MetCys: 0.139 ± 0.011	1.062MetAsp: 1.062 ± 0.033	0.888MetGlu: 0.888 ± 0.028	0.615MetPhe: 0.615 ± 0.026	1.594MetGly: 1.594 ± 0.04	0.473MetHis: 0.473 ± 0.021	0.848MetIle: 0.848 ± 0.028	0.747MetLys: 0.747 ± 0.029	2.273MetLeu: 2.273 ± 0.047	0.436MetMet: 0.436 ± 0.024	0.62MetAsn: 0.62 ± 0.024	1.375MetPro: 1.375 ± 0.041	0.886MetGln: 0.886 ± 0.029	1.746MetArg: 1.746 ± 0.038	1.559MetSer: 1.559 ± 0.035	1.238MetThr: 1.238 ± 0.036	1.358MetVal: 1.358 ± 0.037	0.238MetTrp: 0.238 ± 0.014	0.346MetTyr: 0.346 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.291AsnAla: 3.291 ± 0.078	0.174AsnCys: 0.174 ± 0.012	1.44AsnAsp: 1.44 ± 0.053	1.153AsnGlu: 1.153 ± 0.033	0.871AsnPhe: 0.871 ± 0.038	2.425AsnGly: 2.425 ± 0.077	0.489AsnHis: 0.489 ± 0.023	1.028AsnIle: 1.028 ± 0.034	0.588AsnLys: 0.588 ± 0.028	2.548AsnLeu: 2.548 ± 0.054	0.402AsnMet: 0.402 ± 0.022	0.689AsnAsn: 0.689 ± 0.034	1.698AsnPro: 1.698 ± 0.047	0.787AsnGln: 0.787 ± 0.027	1.589AsnArg: 1.589 ± 0.035	1.107AsnSer: 1.107 ± 0.042	1.382AsnThr: 1.382 ± 0.044	1.947AsnVal: 1.947 ± 0.067	0.396AsnTrp: 0.396 ± 0.019	0.695AsnTyr: 0.695 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	7.93ProAla: 7.93 ± 0.099	0.285ProCys: 0.285 ± 0.018	3.371ProAsp: 3.371 ± 0.061	3.23ProGlu: 3.23 ± 0.059	1.681ProPhe: 1.681 ± 0.035	4.931ProGly: 4.931 ± 0.077	1.105ProHis: 1.105 ± 0.034	1.736ProIle: 1.736 ± 0.041	1.338ProLys: 1.338 ± 0.036	5.643ProLeu: 5.643 ± 0.079	1.255ProMet: 1.255 ± 0.032	1.225ProAsn: 1.225 ± 0.032	2.995ProPro: 2.995 ± 0.07	2.247ProGln: 2.247 ± 0.045	3.572ProArg: 3.572 ± 0.07	2.621ProSer: 2.621 ± 0.047	2.441ProThr: 2.441 ± 0.055	4.413ProVal: 4.413 ± 0.072	0.92ProTrp: 0.92 ± 0.03	1.214ProTyr: 1.214 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	6.211GlnAla: 6.211 ± 0.099	0.247GlnCys: 0.247 ± 0.016	1.744GlnAsp: 1.744 ± 0.045	1.474GlnGlu: 1.474 ± 0.038	1.262GlnPhe: 1.262 ± 0.038	3.096GlnGly: 3.096 ± 0.059	0.864GlnHis: 0.864 ± 0.029	1.508GlnIle: 1.508 ± 0.035	0.921GlnLys: 0.921 ± 0.031	4.599GlnLeu: 4.599 ± 0.061	0.854GlnMet: 0.854 ± 0.031	0.748GlnAsn: 0.748 ± 0.024	2.445GlnPro: 2.445 ± 0.048	2.044GlnGln: 2.044 ± 0.048	3.757GlnArg: 3.757 ± 0.065	1.726GlnSer: 1.726 ± 0.043	1.66GlnThr: 1.66 ± 0.046	3.518GlnVal: 3.518 ± 0.061	0.778GlnTrp: 0.778 ± 0.028	0.888GlnTyr: 0.888 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	8.725ArgAla: 8.725 ± 0.129	0.489ArgCys: 0.489 ± 0.02	4.626ArgAsp: 4.626 ± 0.073	5.06ArgGlu: 5.06 ± 0.084	2.905ArgPhe: 2.905 ± 0.055	5.517ArgGly: 5.517 ± 0.078	2.006ArgHis: 2.006 ± 0.05	3.626ArgIle: 3.626 ± 0.06	1.895ArgLys: 1.895 ± 0.049	8.564ArgLeu: 8.564 ± 0.119	1.871ArgMet: 1.871 ± 0.044	1.856ArgAsn: 1.856 ± 0.045	3.436ArgPro: 3.436 ± 0.063	3.348ArgGln: 3.348 ± 0.054	5.979ArgArg: 5.979 ± 0.104	3.39ArgSer: 3.39 ± 0.063	3.29ArgThr: 3.29 ± 0.058	5.533ArgVal: 5.533 ± 0.081	1.532ArgTrp: 1.532 ± 0.039	2.271ArgTyr: 2.271 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	6.188SerAla: 6.188 ± 0.085	0.343SerCys: 0.343 ± 0.018	2.58SerAsp: 2.58 ± 0.048	2.431SerGlu: 2.431 ± 0.051	1.807SerPhe: 1.807 ± 0.041	4.858SerGly: 4.858 ± 0.084	1.07SerHis: 1.07 ± 0.032	2.044SerIle: 2.044 ± 0.049	1.234SerLys: 1.234 ± 0.04	5.504SerLeu: 5.504 ± 0.068	1.022SerMet: 1.022 ± 0.034	1.374SerAsn: 1.374 ± 0.035	2.793SerPro: 2.793 ± 0.052	1.88SerGln: 1.88 ± 0.05	3.754SerArg: 3.754 ± 0.061	2.595SerSer: 2.595 ± 0.061	2.573SerThr: 2.573 ± 0.055	3.815SerVal: 3.815 ± 0.075	0.833SerTrp: 0.833 ± 0.026	1.285SerTyr: 1.285 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	5.943ThrAla: 5.943 ± 0.096	0.335ThrCys: 0.335 ± 0.021	2.562ThrAsp: 2.562 ± 0.06	2.11ThrGlu: 2.11 ± 0.039	1.559ThrPhe: 1.559 ± 0.038	4.684ThrGly: 4.684 ± 0.089	1.081ThrHis: 1.081 ± 0.029	1.793ThrIle: 1.793 ± 0.049	0.906ThrLys: 0.906 ± 0.032	6.24ThrLeu: 6.24 ± 0.072	0.835ThrMet: 0.835 ± 0.027	1.099ThrAsn: 1.099 ± 0.045	3.567ThrPro: 3.567 ± 0.053	1.726ThrGln: 1.726 ± 0.043	3.463ThrArg: 3.463 ± 0.056	2.269ThrSer: 2.269 ± 0.046	2.595ThrThr: 2.595 ± 0.06	3.891ThrVal: 3.891 ± 0.074	0.725ThrTrp: 0.725 ± 0.027	1.141ThrTyr: 1.141 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	9.889ValAla: 9.889 ± 0.123	0.595ValCys: 0.595 ± 0.021	4.56ValAsp: 4.56 ± 0.073	4.344ValGlu: 4.344 ± 0.071	2.56ValPhe: 2.56 ± 0.054	5.744ValGly: 5.744 ± 0.104	1.594ValHis: 1.594 ± 0.041	3.263ValIle: 3.263 ± 0.063	1.816ValLys: 1.816 ± 0.049	8.436ValLeu: 8.436 ± 0.115	1.62ValMet: 1.62 ± 0.043	2.052ValAsn: 2.052 ± 0.063	4.021ValPro: 4.021 ± 0.049	2.707ValGln: 2.707 ± 0.05	5.449ValArg: 5.449 ± 0.082	4.091ValSer: 4.091 ± 0.059	3.793ValThr: 3.793 ± 0.073	6.23ValVal: 6.23 ± 0.093	0.916ValTrp: 0.916 ± 0.027	1.604ValTyr: 1.604 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.472TrpAla: 1.472 ± 0.041	0.141TrpCys: 0.141 ± 0.012	0.723TrpAsp: 0.723 ± 0.03	0.614TrpGlu: 0.614 ± 0.025	0.61TrpPhe: 0.61 ± 0.024	1.044TrpGly: 1.044 ± 0.04	0.42TrpHis: 0.42 ± 0.018	0.731TrpIle: 0.731 ± 0.027	0.451TrpLys: 0.451 ± 0.022	2.375TrpLeu: 2.375 ± 0.056	0.434TrpMet: 0.434 ± 0.02	0.517TrpAsn: 0.517 ± 0.022	0.888TrpPro: 0.888 ± 0.032	0.869TrpGln: 0.869 ± 0.027	1.664TrpArg: 1.664 ± 0.05	0.921TrpSer: 0.921 ± 0.027	0.747TrpThr: 0.747 ± 0.025	1.034TrpVal: 1.034 ± 0.028	0.383TrpTrp: 0.383 ± 0.022	0.403TrpTyr: 0.403 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.064TyrAla: 3.064 ± 0.053	0.203TyrCys: 0.203 ± 0.013	1.497TyrAsp: 1.497 ± 0.037	1.216TyrGlu: 1.216 ± 0.035	0.926TyrPhe: 0.926 ± 0.029	2.205TyrGly: 2.205 ± 0.054	0.522TyrHis: 0.522 ± 0.021	0.769TyrIle: 0.769 ± 0.026	0.537TyrLys: 0.537 ± 0.024	2.548TyrLeu: 2.548 ± 0.043	0.367TyrMet: 0.367 ± 0.019	0.712TyrAsn: 0.712 ± 0.034	1.129TyrPro: 1.129 ± 0.032	0.918TyrGln: 0.918 ± 0.03	2.084TyrArg: 2.084 ± 0.041	1.285TyrSer: 1.285 ± 0.039	1.289TyrThr: 1.289 ± 0.039	1.745TyrVal: 1.745 ± 0.045	0.405TyrTrp: 0.405 ± 0.019	0.7TyrTyr: 0.7 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3403 proteins (1150310 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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