Amino acid dipepetide frequency for New Jersey polyomavirus-2013

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.286AlaAla: 4.286 ± 0.947
0.476AlaCys: 0.476 ± 0.342
3.333AlaAsp: 3.333 ± 1.354
1.429AlaGlu: 1.429 ± 0.739
2.381AlaPhe: 2.381 ± 1.528
2.857AlaGly: 2.857 ± 0.475
2.857AlaHis: 2.857 ± 0.865
3.333AlaIle: 3.333 ± 0.489
3.81AlaLys: 3.81 ± 2.047
5.714AlaLeu: 5.714 ± 1.628
0.952AlaMet: 0.952 ± 0.684
2.857AlaAsn: 2.857 ± 2.051
2.857AlaPro: 2.857 ± 1.698
2.857AlaGln: 2.857 ± 0.908
0.476AlaArg: 0.476 ± 0.383
6.19AlaSer: 6.19 ± 1.581
2.381AlaThr: 2.381 ± 1.318
4.762AlaVal: 4.762 ± 1.823
0.476AlaTrp: 0.476 ± 0.342
3.81AlaTyr: 3.81 ± 1.268
0.0AlaXaa: 0.0 ± 0.0
Cys
1.905CysAla: 1.905 ± 1.023
0.952CysCys: 0.952 ± 0.728
0.476CysAsp: 0.476 ± 0.342
1.905CysGlu: 1.905 ± 0.676
1.905CysPhe: 1.905 ± 1.662
1.429CysGly: 1.429 ± 0.747
0.0CysHis: 0.0 ± 0.0
1.429CysIle: 1.429 ± 0.651
2.857CysLys: 2.857 ± 1.188
4.762CysLeu: 4.762 ± 2.261
0.0CysMet: 0.0 ± 0.0
0.952CysAsn: 0.952 ± 0.684
1.905CysPro: 1.905 ± 0.676
1.429CysGln: 1.429 ± 0.651
0.0CysArg: 0.0 ± 0.0
2.381CysSer: 2.381 ± 1.338
0.476CysThr: 0.476 ± 0.342
0.952CysVal: 0.952 ± 0.365
0.0CysTrp: 0.0 ± 0.0
1.429CysTyr: 1.429 ± 0.651
0.0CysXaa: 0.0 ± 0.0
Asp
0.952AspAla: 0.952 ± 0.767
0.952AspCys: 0.952 ± 0.728
0.952AspAsp: 0.952 ± 0.684
2.381AspGlu: 2.381 ± 1.222
2.381AspPhe: 2.381 ± 1.709
3.81AspGly: 3.81 ± 1.662
0.476AspHis: 0.476 ± 0.342
2.381AspIle: 2.381 ± 0.924
5.714AspLys: 5.714 ± 1.481
3.81AspLeu: 3.81 ± 1.37
1.905AspMet: 1.905 ± 0.859
1.905AspAsn: 1.905 ± 0.729
2.381AspPro: 2.381 ± 0.813
1.905AspGln: 1.905 ± 1.027
0.952AspArg: 0.952 ± 0.365
4.286AspSer: 4.286 ± 1.676
0.952AspThr: 0.952 ± 0.525
0.476AspVal: 0.476 ± 0.342
0.952AspTrp: 0.952 ± 0.824
0.952AspTyr: 0.952 ± 0.684
0.0AspXaa: 0.0 ± 0.0
Glu
4.762GluAla: 4.762 ± 1.697
0.476GluCys: 0.476 ± 0.342
2.381GluAsp: 2.381 ± 1.222
5.714GluGlu: 5.714 ± 1.79
1.905GluPhe: 1.905 ± 0.805
4.286GluGly: 4.286 ± 0.254
0.952GluHis: 0.952 ± 0.365
2.381GluIle: 2.381 ± 0.564
8.571GluLys: 8.571 ± 1.658
5.238GluLeu: 5.238 ± 1.096
1.905GluMet: 1.905 ± 0.567
3.81GluAsn: 3.81 ± 0.938
2.381GluPro: 2.381 ± 0.813
3.333GluGln: 3.333 ± 1.609
1.905GluArg: 1.905 ± 0.703
6.19GluSer: 6.19 ± 1.032
3.333GluThr: 3.333 ± 1.057
7.619GluVal: 7.619 ± 1.617
0.952GluTrp: 0.952 ± 0.767
0.952GluTyr: 0.952 ± 0.365
0.0GluXaa: 0.0 ± 0.0
Phe
2.857PheAla: 2.857 ± 1.553
1.905PheCys: 1.905 ± 0.997
2.381PheAsp: 2.381 ± 0.653
3.81PheGlu: 3.81 ± 1.453
0.476PhePhe: 0.476 ± 0.342
1.905PheGly: 1.905 ± 1.037
1.905PheHis: 1.905 ± 1.037
1.905PheIle: 1.905 ± 0.911
1.429PheLys: 1.429 ± 0.594
3.333PheLeu: 3.333 ± 0.947
0.952PheMet: 0.952 ± 0.502
1.905PheAsn: 1.905 ± 1.648
3.333PhePro: 3.333 ± 1.528
3.333PheGln: 3.333 ± 0.843
0.952PheArg: 0.952 ± 0.684
7.143PheSer: 7.143 ± 1.681
2.381PheThr: 2.381 ± 1.003
2.857PheVal: 2.857 ± 1.188
0.0PheTrp: 0.0 ± 0.0
0.476PheTyr: 0.476 ± 0.383
0.0PheXaa: 0.0 ± 0.0
Gly
3.333GlyAla: 3.333 ± 1.354
0.476GlyCys: 0.476 ± 0.342
1.429GlyAsp: 1.429 ± 0.666
1.429GlyGlu: 1.429 ± 0.491
0.952GlyPhe: 0.952 ± 0.767
7.143GlyGly: 7.143 ± 1.246
0.0GlyHis: 0.0 ± 0.0
6.667GlyIle: 6.667 ± 2.805
3.333GlyLys: 3.333 ± 0.918
8.571GlyLeu: 8.571 ± 1.455
0.476GlyMet: 0.476 ± 0.383
1.905GlyAsn: 1.905 ± 1.117
3.81GlyPro: 3.81 ± 1.689
2.381GlyGln: 2.381 ± 1.003
1.905GlyArg: 1.905 ± 0.805
4.286GlySer: 4.286 ± 0.951
3.81GlyThr: 3.81 ± 1.621
4.286GlyVal: 4.286 ± 1.82
0.952GlyTrp: 0.952 ± 0.824
2.857GlyTyr: 2.857 ± 1.076
0.0GlyXaa: 0.0 ± 0.0
His
0.952HisAla: 0.952 ± 0.365
0.476HisCys: 0.476 ± 0.342
0.476HisAsp: 0.476 ± 0.342
1.429HisGlu: 1.429 ± 0.651
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
1.429HisHis: 1.429 ± 0.483
0.0HisIle: 0.0 ± 0.0
1.905HisLys: 1.905 ± 0.729
2.381HisLeu: 2.381 ± 1.628
1.429HisMet: 1.429 ± 0.594
0.0HisAsn: 0.0 ± 0.0
2.381HisPro: 2.381 ± 0.929
2.381HisGln: 2.381 ± 0.971
1.429HisArg: 1.429 ± 0.651
0.476HisSer: 0.476 ± 0.342
0.0HisThr: 0.0 ± 0.0
1.429HisVal: 1.429 ± 1.046
0.0HisTrp: 0.0 ± 0.0
0.476HisTyr: 0.476 ± 0.342
0.0HisXaa: 0.0 ± 0.0
Ile
2.857IleAla: 2.857 ± 0.721
1.905IleCys: 1.905 ± 0.601
2.381IleAsp: 2.381 ± 1.222
8.571IleGlu: 8.571 ± 1.442
1.429IlePhe: 1.429 ± 0.739
2.381IleGly: 2.381 ± 1.628
2.381IleHis: 2.381 ± 1.297
0.952IleIle: 0.952 ± 0.365
1.429IleLys: 1.429 ± 1.105
6.19IleLeu: 6.19 ± 1.606
1.429IleMet: 1.429 ± 0.651
0.0IleAsn: 0.0 ± 0.0
3.333IlePro: 3.333 ± 0.878
1.429IleGln: 1.429 ± 0.847
1.429IleArg: 1.429 ± 0.848
4.286IleSer: 4.286 ± 2.156
2.381IleThr: 2.381 ± 1.224
1.429IleVal: 1.429 ± 0.554
1.429IleTrp: 1.429 ± 0.651
2.857IleTyr: 2.857 ± 0.877
0.0IleXaa: 0.0 ± 0.0
Lys
4.286LysAla: 4.286 ± 1.63
2.381LysCys: 2.381 ± 0.564
0.952LysAsp: 0.952 ± 0.365
3.81LysGlu: 3.81 ± 1.176
2.857LysPhe: 2.857 ± 0.74
4.762LysGly: 4.762 ± 1.38
1.429LysHis: 1.429 ± 0.736
3.81LysIle: 3.81 ± 0.958
4.762LysLys: 4.762 ± 1.821
6.19LysLeu: 6.19 ± 0.687
4.286LysMet: 4.286 ± 0.641
0.952LysAsn: 0.952 ± 0.365
1.905LysPro: 1.905 ± 0.601
2.857LysGln: 2.857 ± 1.068
6.19LysArg: 6.19 ± 1.38
4.286LysSer: 4.286 ± 1.374
6.19LysThr: 6.19 ± 1.068
5.238LysVal: 5.238 ± 1.774
0.952LysTrp: 0.952 ± 0.767
0.952LysTyr: 0.952 ± 0.582
0.0LysXaa: 0.0 ± 0.0
Leu
4.762LeuAla: 4.762 ± 1.695
1.905LeuCys: 1.905 ± 0.567
5.238LeuAsp: 5.238 ± 1.428
6.19LeuGlu: 6.19 ± 1.027
7.619LeuPhe: 7.619 ± 1.443
6.19LeuGly: 6.19 ± 1.819
1.905LeuHis: 1.905 ± 1.05
11.905LeuIle: 11.905 ± 2.879
4.762LeuLys: 4.762 ± 1.867
14.762LeuLeu: 14.762 ± 3.23
2.381LeuMet: 2.381 ± 1.167
6.19LeuAsn: 6.19 ± 0.794
5.714LeuPro: 5.714 ± 2.157
5.714LeuGln: 5.714 ± 1.465
3.81LeuArg: 3.81 ± 1.789
5.714LeuSer: 5.714 ± 3.107
5.238LeuThr: 5.238 ± 1.199
4.286LeuVal: 4.286 ± 0.959
2.381LeuTrp: 2.381 ± 1.042
2.381LeuTyr: 2.381 ± 1.03
0.0LeuXaa: 0.0 ± 0.0
Met
2.857MetAla: 2.857 ± 0.926
0.476MetCys: 0.476 ± 0.342
0.952MetAsp: 0.952 ± 0.582
2.857MetGlu: 2.857 ± 0.697
1.429MetPhe: 1.429 ± 0.848
0.952MetGly: 0.952 ± 0.591
0.0MetHis: 0.0 ± 0.0
0.476MetIle: 0.476 ± 0.505
3.81MetLys: 3.81 ± 1.78
5.238MetLeu: 5.238 ± 0.949
1.905MetMet: 1.905 ± 0.567
1.429MetAsn: 1.429 ± 0.594
2.381MetPro: 2.381 ± 1.036
0.476MetGln: 0.476 ± 0.5
0.476MetArg: 0.476 ± 0.342
0.952MetSer: 0.952 ± 0.582
2.381MetThr: 2.381 ± 0.653
0.0MetVal: 0.0 ± 0.0
0.476MetTrp: 0.476 ± 0.383
0.476MetTyr: 0.476 ± 0.383
0.0MetXaa: 0.0 ± 0.0
Asn
2.857AsnAla: 2.857 ± 0.707
1.429AsnCys: 1.429 ± 0.736
0.476AsnAsp: 0.476 ± 0.383
1.905AsnGlu: 1.905 ± 0.729
4.286AsnPhe: 4.286 ± 1.279
2.857AsnGly: 2.857 ± 1.697
0.0AsnHis: 0.0 ± 0.0
1.905AsnIle: 1.905 ± 0.898
2.857AsnLys: 2.857 ± 1.648
4.286AsnLeu: 4.286 ± 0.993
1.905AsnMet: 1.905 ± 0.996
0.476AsnAsn: 0.476 ± 0.383
1.429AsnPro: 1.429 ± 0.848
1.429AsnGln: 1.429 ± 0.651
1.429AsnArg: 1.429 ± 0.739
3.81AsnSer: 3.81 ± 0.883
0.952AsnThr: 0.952 ± 0.365
0.952AsnVal: 0.952 ± 0.684
1.905AsnTrp: 1.905 ± 0.805
0.476AsnTyr: 0.476 ± 0.383
0.0AsnXaa: 0.0 ± 0.0
Pro
2.857ProAla: 2.857 ± 1.383
0.952ProCys: 0.952 ± 0.684
4.762ProAsp: 4.762 ± 1.003
1.429ProGlu: 1.429 ± 0.483
2.857ProPhe: 2.857 ± 1.245
2.857ProGly: 2.857 ± 0.707
0.0ProHis: 0.0 ± 0.0
3.333ProIle: 3.333 ± 0.856
5.238ProLys: 5.238 ± 1.445
5.238ProLeu: 5.238 ± 1.472
2.857ProMet: 2.857 ± 1.182
1.905ProAsn: 1.905 ± 1.023
9.524ProPro: 9.524 ± 2.738
3.81ProGln: 3.81 ± 1.289
4.762ProArg: 4.762 ± 1.991
5.238ProSer: 5.238 ± 0.771
5.714ProThr: 5.714 ± 1.68
3.333ProVal: 3.333 ± 0.757
0.0ProTrp: 0.0 ± 0.0
0.476ProTyr: 0.476 ± 0.383
0.0ProXaa: 0.0 ± 0.0
Gln
1.905GlnAla: 1.905 ± 1.05
1.429GlnCys: 1.429 ± 0.651
0.476GlnAsp: 0.476 ± 0.5
5.238GlnGlu: 5.238 ± 1.108
2.857GlnPhe: 2.857 ± 0.707
2.381GlnGly: 2.381 ± 1.395
0.952GlnHis: 0.952 ± 0.728
2.381GlnIle: 2.381 ± 0.929
4.762GlnLys: 4.762 ± 1.158
3.81GlnLeu: 3.81 ± 1.574
1.905GlnMet: 1.905 ± 0.943
1.905GlnAsn: 1.905 ± 0.601
1.905GlnPro: 1.905 ± 0.601
0.476GlnGln: 0.476 ± 0.342
2.857GlnArg: 2.857 ± 0.928
0.952GlnSer: 0.952 ± 0.684
5.714GlnThr: 5.714 ± 2.261
2.381GlnVal: 2.381 ± 0.564
0.0GlnTrp: 0.0 ± 0.0
0.952GlnTyr: 0.952 ± 0.582
0.0GlnXaa: 0.0 ± 0.0
Arg
3.81ArgAla: 3.81 ± 0.707
0.952ArgCys: 0.952 ± 0.652
2.381ArgAsp: 2.381 ± 1.03
3.333ArgGlu: 3.333 ± 1.311
0.952ArgPhe: 0.952 ± 0.684
1.429ArgGly: 1.429 ± 0.594
0.952ArgHis: 0.952 ± 0.824
0.952ArgIle: 0.952 ± 0.365
2.857ArgLys: 2.857 ± 0.947
3.333ArgLeu: 3.333 ± 1.519
0.476ArgMet: 0.476 ± 0.383
1.429ArgAsn: 1.429 ± 0.594
1.429ArgPro: 1.429 ± 0.666
0.952ArgGln: 0.952 ± 0.728
1.905ArgArg: 1.905 ± 1.014
3.333ArgSer: 3.333 ± 1.499
0.0ArgThr: 0.0 ± 0.0
1.429ArgVal: 1.429 ± 0.483
0.952ArgTrp: 0.952 ± 0.824
4.762ArgTyr: 4.762 ± 1.003
0.0ArgXaa: 0.0 ± 0.0
Ser
4.762SerAla: 4.762 ± 1.279
5.238SerCys: 5.238 ± 2.441
5.714SerAsp: 5.714 ± 1.927
4.762SerGlu: 4.762 ± 1.38
4.286SerPhe: 4.286 ± 0.624
5.238SerGly: 5.238 ± 2.425
0.952SerHis: 0.952 ± 0.684
1.905SerIle: 1.905 ± 0.676
2.857SerLys: 2.857 ± 0.715
11.429SerLeu: 11.429 ± 1.633
0.0SerMet: 0.0 ± 0.0
3.333SerAsn: 3.333 ± 1.363
7.619SerPro: 7.619 ± 2.723
3.333SerGln: 3.333 ± 1.534
2.381SerArg: 2.381 ± 1.003
9.048SerSer: 9.048 ± 2.601
4.286SerThr: 4.286 ± 1.626
4.762SerVal: 4.762 ± 1.5
0.476SerTrp: 0.476 ± 0.342
1.905SerTyr: 1.905 ± 0.898
0.0SerXaa: 0.0 ± 0.0
Thr
3.333ThrAla: 3.333 ± 0.509
0.952ThrCys: 0.952 ± 0.767
1.905ThrAsp: 1.905 ± 0.729
8.571ThrGlu: 8.571 ± 2.4
1.905ThrPhe: 1.905 ± 0.911
1.905ThrGly: 1.905 ± 1.191
0.0ThrHis: 0.0 ± 0.0
1.429ThrIle: 1.429 ± 0.739
1.905ThrLys: 1.905 ± 0.676
3.81ThrLeu: 3.81 ± 1.203
0.952ThrMet: 0.952 ± 0.528
0.952ThrAsn: 0.952 ± 0.365
7.619ThrPro: 7.619 ± 2.026
1.905ThrGln: 1.905 ± 0.729
1.429ThrArg: 1.429 ± 0.967
5.714ThrSer: 5.714 ± 1.071
4.286ThrThr: 4.286 ± 1.479
5.238ThrVal: 5.238 ± 1.908
0.952ThrTrp: 0.952 ± 1.163
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.905ValAla: 1.905 ± 0.898
2.381ValCys: 2.381 ± 1.248
1.429ValAsp: 1.429 ± 0.731
2.381ValGlu: 2.381 ± 1.297
3.333ValPhe: 3.333 ± 1.142
2.857ValGly: 2.857 ± 1.331
0.476ValHis: 0.476 ± 0.383
2.857ValIle: 2.857 ± 1.756
2.857ValLys: 2.857 ± 1.094
8.095ValLeu: 8.095 ± 1.166
2.381ValMet: 2.381 ± 0.494
4.286ValAsn: 4.286 ± 1.415
3.333ValPro: 3.333 ± 0.931
1.905ValGln: 1.905 ± 1.182
2.857ValArg: 2.857 ± 0.877
7.619ValSer: 7.619 ± 0.616
1.429ValThr: 1.429 ± 0.849
2.381ValVal: 2.381 ± 0.653
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.429TrpCys: 1.429 ± 0.739
0.0TrpAsp: 0.0 ± 0.0
0.476TrpGlu: 0.476 ± 0.383
0.476TrpPhe: 0.476 ± 0.581
0.952TrpGly: 0.952 ± 0.652
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.905TrpLys: 1.905 ± 1.05
0.476TrpLeu: 0.476 ± 0.383
1.429TrpMet: 1.429 ± 0.847
0.476TrpAsn: 0.476 ± 0.342
0.0TrpPro: 0.0 ± 0.0
1.429TrpGln: 1.429 ± 0.651
0.0TrpArg: 0.0 ± 0.0
0.476TrpSer: 0.476 ± 0.383
0.952TrpThr: 0.952 ± 0.824
0.952TrpVal: 0.952 ± 0.824
0.0TrpTrp: 0.0 ± 0.0
1.429TrpTyr: 1.429 ± 0.594
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.857TyrAla: 2.857 ± 0.74
0.0TyrCys: 0.0 ± 0.0
2.381TyrAsp: 2.381 ± 0.564
1.429TyrGlu: 1.429 ± 0.739
0.952TyrPhe: 0.952 ± 0.365
3.81TyrGly: 3.81 ± 0.463
2.381TyrHis: 2.381 ± 0.564
0.476TyrIle: 0.476 ± 0.383
1.429TyrLys: 1.429 ± 0.651
2.381TyrLeu: 2.381 ± 0.933
0.0TyrMet: 0.0 ± 0.0
1.429TyrAsn: 1.429 ± 0.651
1.905TyrPro: 1.905 ± 1.182
1.905TyrGln: 1.905 ± 0.676
0.476TyrArg: 0.476 ± 0.383
1.905TyrSer: 1.905 ± 1.023
1.905TyrThr: 1.905 ± 0.601
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.476TyrTyr: 0.476 ± 0.383
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2101 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski