Amino acid dipepetide frequency for Torque teno Leptonychotes weddellii virus-2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.285AlaAla: 1.285 ± 0.68
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
2.571AlaGlu: 2.571 ± 1.293
0.0AlaPhe: 0.0 ± 0.0
1.285AlaGly: 1.285 ± 0.68
1.285AlaHis: 1.285 ± 0.68
2.571AlaIle: 2.571 ± 1.939
2.571AlaLys: 2.571 ± 1.293
6.427AlaLeu: 6.427 ± 4.643
2.571AlaMet: 2.571 ± 3.297
2.571AlaAsn: 2.571 ± 1.359
2.571AlaPro: 2.571 ± 1.464
1.285AlaGln: 1.285 ± 1.791
2.571AlaArg: 2.571 ± 1.359
2.571AlaSer: 2.571 ± 1.464
2.571AlaThr: 2.571 ± 1.293
5.141AlaVal: 5.141 ± 3.748
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.285CysAla: 1.285 ± 0.68
1.285CysCys: 1.285 ± 0.68
0.0CysAsp: 0.0 ± 0.0
1.285CysGlu: 1.285 ± 0.68
2.571CysPhe: 2.571 ± 4.499
2.571CysGly: 2.571 ± 2.999
0.0CysHis: 0.0 ± 0.0
1.285CysIle: 1.285 ± 0.68
2.571CysLys: 2.571 ± 1.359
1.285CysLeu: 1.285 ± 2.249
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.571CysPro: 2.571 ± 1.359
1.285CysGln: 1.285 ± 1.791
0.0CysArg: 0.0 ± 0.0
1.285CysSer: 1.285 ± 0.68
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
1.285CysTrp: 1.285 ± 1.791
1.285CysTyr: 1.285 ± 1.648
0.0CysXaa: 0.0 ± 0.0
Asp
2.571AspAla: 2.571 ± 1.464
0.0AspCys: 0.0 ± 0.0
0.0AspAsp: 0.0 ± 0.0
1.285AspGlu: 1.285 ± 1.791
1.285AspPhe: 1.285 ± 1.648
3.856AspGly: 3.856 ± 1.245
0.0AspHis: 0.0 ± 0.0
5.141AspIle: 5.141 ± 2.586
2.571AspLys: 2.571 ± 1.359
8.997AspLeu: 8.997 ± 2.862
2.571AspMet: 2.571 ± 1.474
2.571AspAsn: 2.571 ± 1.939
3.856AspPro: 3.856 ± 2.884
0.0AspGln: 0.0 ± 0.0
3.856AspArg: 3.856 ± 1.245
6.427AspSer: 6.427 ± 2.798
2.571AspThr: 2.571 ± 2.999
1.285AspVal: 1.285 ± 0.68
3.856AspTrp: 3.856 ± 2.039
2.571AspTyr: 2.571 ± 1.359
0.0AspXaa: 0.0 ± 0.0
Glu
5.141GluAla: 5.141 ± 1.534
1.285GluCys: 1.285 ± 0.68
2.571GluAsp: 2.571 ± 1.464
5.141GluGlu: 5.141 ± 3.672
2.571GluPhe: 2.571 ± 2.871
5.141GluGly: 5.141 ± 3.56
1.285GluHis: 1.285 ± 1.648
1.285GluIle: 1.285 ± 0.68
3.856GluLys: 3.856 ± 1.245
2.571GluLeu: 2.571 ± 1.464
0.0GluMet: 0.0 ± 0.0
1.285GluAsn: 1.285 ± 1.791
1.285GluPro: 1.285 ± 0.68
2.571GluGln: 2.571 ± 1.464
2.571GluArg: 2.571 ± 2.871
7.712GluSer: 7.712 ± 2.693
6.427GluThr: 6.427 ± 4.14
0.0GluVal: 0.0 ± 0.0
1.285GluTrp: 1.285 ± 0.68
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.285PheAla: 1.285 ± 0.68
2.571PheCys: 2.571 ± 1.293
2.571PheAsp: 2.571 ± 1.939
1.285PheGlu: 1.285 ± 1.791
6.427PhePhe: 6.427 ± 2.325
1.285PheGly: 1.285 ± 0.68
3.856PheHis: 3.856 ± 1.245
0.0PheIle: 0.0 ± 0.0
3.856PheLys: 3.856 ± 1.245
3.856PheLeu: 3.856 ± 1.415
2.571PheMet: 2.571 ± 2.176
1.285PheAsn: 1.285 ± 0.68
0.0PhePro: 0.0 ± 0.0
1.285PheGln: 1.285 ± 2.249
7.712PheArg: 7.712 ± 2.83
5.141PheSer: 5.141 ± 1.534
1.285PheThr: 1.285 ± 2.249
0.0PheVal: 0.0 ± 0.0
1.285PheTrp: 1.285 ± 0.68
1.285PheTyr: 1.285 ± 0.68
0.0PheXaa: 0.0 ± 0.0
Gly
2.571GlyAla: 2.571 ± 2.557
1.285GlyCys: 1.285 ± 0.68
8.997GlyAsp: 8.997 ± 5.435
6.427GlyGlu: 6.427 ± 2.841
1.285GlyPhe: 1.285 ± 0.68
19.28GlyGly: 19.28 ± 7.988
1.285GlyHis: 1.285 ± 0.68
5.141GlyIle: 5.141 ± 1.534
2.571GlyLys: 2.571 ± 1.939
3.856GlyLeu: 3.856 ± 1.84
2.571GlyMet: 2.571 ± 1.939
1.285GlyAsn: 1.285 ± 0.68
10.283GlyPro: 10.283 ± 3.046
2.571GlyGln: 2.571 ± 1.359
5.141GlyArg: 5.141 ± 2.719
7.712GlySer: 7.712 ± 2.417
1.285GlyThr: 1.285 ± 1.648
1.285GlyVal: 1.285 ± 1.648
2.571GlyTrp: 2.571 ± 1.939
2.571GlyTyr: 2.571 ± 1.293
0.0GlyXaa: 0.0 ± 0.0
His
2.571HisAla: 2.571 ± 3.297
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
2.571HisPhe: 2.571 ± 1.293
0.0HisGly: 0.0 ± 0.0
1.285HisHis: 1.285 ± 0.68
2.571HisIle: 2.571 ± 1.359
1.285HisLys: 1.285 ± 0.68
2.571HisLeu: 2.571 ± 1.939
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.571HisPro: 2.571 ± 1.293
0.0HisGln: 0.0 ± 0.0
7.712HisArg: 7.712 ± 4.078
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
2.571HisTrp: 2.571 ± 1.359
1.285HisTyr: 1.285 ± 0.68
0.0HisXaa: 0.0 ± 0.0
Ile
1.285IleAla: 1.285 ± 1.648
0.0IleCys: 0.0 ± 0.0
3.856IleAsp: 3.856 ± 1.245
5.141IleGlu: 5.141 ± 3.672
2.571IlePhe: 2.571 ± 1.293
2.571IleGly: 2.571 ± 1.293
1.285IleHis: 1.285 ± 0.68
2.571IleIle: 2.571 ± 1.359
2.571IleLys: 2.571 ± 1.359
8.997IleLeu: 8.997 ± 3.335
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
1.285IlePro: 1.285 ± 0.68
2.571IleGln: 2.571 ± 1.939
1.285IleArg: 1.285 ± 0.68
3.856IleSer: 3.856 ± 2.884
0.0IleThr: 0.0 ± 0.0
1.285IleVal: 1.285 ± 0.68
1.285IleTrp: 1.285 ± 0.68
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.571LysAla: 2.571 ± 2.557
0.0LysCys: 0.0 ± 0.0
3.856LysAsp: 3.856 ± 2.487
3.856LysGlu: 3.856 ± 1.245
2.571LysPhe: 2.571 ± 1.293
1.285LysGly: 1.285 ± 1.791
1.285LysHis: 1.285 ± 0.68
2.571LysIle: 2.571 ± 1.359
3.856LysLys: 3.856 ± 1.415
3.856LysLeu: 3.856 ± 1.84
1.285LysMet: 1.285 ± 0.68
1.285LysAsn: 1.285 ± 0.68
3.856LysPro: 3.856 ± 2.039
5.141LysGln: 5.141 ± 1.983
7.712LysArg: 7.712 ± 2.595
0.0LysSer: 0.0 ± 0.0
2.571LysThr: 2.571 ± 1.359
3.856LysVal: 3.856 ± 1.84
1.285LysTrp: 1.285 ± 1.648
3.856LysTyr: 3.856 ± 1.415
0.0LysXaa: 0.0 ± 0.0
Leu
6.427LeuAla: 6.427 ± 3.171
2.571LeuCys: 2.571 ± 4.499
3.856LeuAsp: 3.856 ± 1.415
3.856LeuGlu: 3.856 ± 1.415
1.285LeuPhe: 1.285 ± 1.791
6.427LeuGly: 6.427 ± 2.12
3.856LeuHis: 3.856 ± 1.84
3.856LeuIle: 3.856 ± 3.576
3.856LeuLys: 3.856 ± 1.84
10.283LeuLeu: 10.283 ± 5.368
1.285LeuMet: 1.285 ± 0.68
2.571LeuAsn: 2.571 ± 1.293
7.712LeuPro: 7.712 ± 2.669
5.141LeuGln: 5.141 ± 1.983
5.141LeuArg: 5.141 ± 1.523
3.856LeuSer: 3.856 ± 1.992
2.571LeuThr: 2.571 ± 1.939
6.427LeuVal: 6.427 ± 1.592
2.571LeuTrp: 2.571 ± 1.939
5.141LeuTyr: 5.141 ± 6.38
0.0LeuXaa: 0.0 ± 0.0
Met
3.856MetAla: 3.856 ± 1.415
0.0MetCys: 0.0 ± 0.0
5.141MetAsp: 5.141 ± 1.983
2.571MetGlu: 2.571 ± 2.999
2.571MetPhe: 2.571 ± 1.359
1.285MetGly: 1.285 ± 0.68
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.571MetLeu: 2.571 ± 2.999
0.0MetMet: 0.0 ± 0.0
1.285MetAsn: 1.285 ± 0.68
1.285MetPro: 1.285 ± 0.68
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.285MetSer: 1.285 ± 1.648
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
2.571MetTyr: 2.571 ± 1.359
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
0.0AsnGlu: 0.0 ± 0.0
2.571AsnPhe: 2.571 ± 1.939
2.571AsnGly: 2.571 ± 1.359
1.285AsnHis: 1.285 ± 1.648
0.0AsnIle: 0.0 ± 0.0
2.571AsnLys: 2.571 ± 1.464
1.285AsnLeu: 1.285 ± 0.68
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.285AsnPro: 1.285 ± 1.791
2.571AsnGln: 2.571 ± 1.359
1.285AsnArg: 1.285 ± 0.68
1.285AsnSer: 1.285 ± 0.68
1.285AsnThr: 1.285 ± 0.68
1.285AsnVal: 1.285 ± 0.68
1.285AsnTrp: 1.285 ± 0.68
1.285AsnTyr: 1.285 ± 0.68
0.0AsnXaa: 0.0 ± 0.0
Pro
2.571ProAla: 2.571 ± 1.359
2.571ProCys: 2.571 ± 1.464
2.571ProAsp: 2.571 ± 1.293
3.856ProGlu: 3.856 ± 1.992
2.571ProPhe: 2.571 ± 1.359
6.427ProGly: 6.427 ± 1.264
1.285ProHis: 1.285 ± 0.68
1.285ProIle: 1.285 ± 1.648
2.571ProLys: 2.571 ± 1.359
7.712ProLeu: 7.712 ± 2.83
2.571ProMet: 2.571 ± 1.359
0.0ProAsn: 0.0 ± 0.0
8.997ProPro: 8.997 ± 3.019
1.285ProGln: 1.285 ± 0.68
3.856ProArg: 3.856 ± 2.039
6.427ProSer: 6.427 ± 1.264
6.427ProThr: 6.427 ± 1.264
0.0ProVal: 0.0 ± 0.0
1.285ProTrp: 1.285 ± 0.68
5.141ProTyr: 5.141 ± 1.669
0.0ProXaa: 0.0 ± 0.0
Gln
1.285GlnAla: 1.285 ± 2.249
1.285GlnCys: 1.285 ± 2.249
2.571GlnAsp: 2.571 ± 1.464
0.0GlnGlu: 0.0 ± 0.0
1.285GlnPhe: 1.285 ± 0.68
1.285GlnGly: 1.285 ± 0.68
0.0GlnHis: 0.0 ± 0.0
1.285GlnIle: 1.285 ± 0.68
1.285GlnLys: 1.285 ± 0.68
5.141GlnLeu: 5.141 ± 3.878
3.856GlnMet: 3.856 ± 1.925
1.285GlnAsn: 1.285 ± 0.68
3.856GlnPro: 3.856 ± 1.415
6.427GlnGln: 6.427 ± 3.399
3.856GlnArg: 3.856 ± 1.415
2.571GlnSer: 2.571 ± 1.359
1.285GlnThr: 1.285 ± 1.791
1.285GlnVal: 1.285 ± 0.68
1.285GlnTrp: 1.285 ± 1.791
1.285GlnTyr: 1.285 ± 0.68
0.0GlnXaa: 0.0 ± 0.0
Arg
1.285ArgAla: 1.285 ± 0.68
0.0ArgCys: 0.0 ± 0.0
1.285ArgAsp: 1.285 ± 0.68
5.141ArgGlu: 5.141 ± 2.928
5.141ArgPhe: 5.141 ± 1.669
3.856ArgGly: 3.856 ± 1.245
5.141ArgHis: 5.141 ± 2.719
3.856ArgIle: 3.856 ± 2.039
3.856ArgLys: 3.856 ± 1.245
7.712ArgLeu: 7.712 ± 3.493
1.285ArgMet: 1.285 ± 1.334
1.285ArgAsn: 1.285 ± 0.68
6.427ArgPro: 6.427 ± 3.399
3.856ArgGln: 3.856 ± 2.039
19.28ArgArg: 19.28 ± 10.196
7.712ArgSer: 7.712 ± 2.669
1.285ArgThr: 1.285 ± 0.68
1.285ArgVal: 1.285 ± 0.68
5.141ArgTrp: 5.141 ± 2.719
3.856ArgTyr: 3.856 ± 2.039
0.0ArgXaa: 0.0 ± 0.0
Ser
1.285SerAla: 1.285 ± 1.648
0.0SerCys: 0.0 ± 0.0
7.712SerAsp: 7.712 ± 1.341
6.427SerGlu: 6.427 ± 2.798
5.141SerPhe: 5.141 ± 2.928
8.997SerGly: 8.997 ± 3.71
3.856SerHis: 3.856 ± 1.245
2.571SerIle: 2.571 ± 1.464
5.141SerLys: 5.141 ± 3.56
1.285SerLeu: 1.285 ± 0.68
0.0SerMet: 0.0 ± 0.0
1.285SerAsn: 1.285 ± 1.791
2.571SerPro: 2.571 ± 1.359
3.856SerGln: 3.856 ± 1.415
2.571SerArg: 2.571 ± 1.359
8.997SerSer: 8.997 ± 3.48
3.856SerThr: 3.856 ± 1.992
2.571SerVal: 2.571 ± 1.939
3.856SerTrp: 3.856 ± 1.415
3.856SerTyr: 3.856 ± 1.245
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
0.0ThrCys: 0.0 ± 0.0
5.141ThrAsp: 5.141 ± 3.56
0.0ThrGlu: 0.0 ± 0.0
1.285ThrPhe: 1.285 ± 0.68
11.568ThrGly: 11.568 ± 9.1
0.0ThrHis: 0.0 ± 0.0
1.285ThrIle: 1.285 ± 1.648
1.285ThrLys: 1.285 ± 0.68
2.571ThrLeu: 2.571 ± 1.939
1.285ThrMet: 1.285 ± 0.68
0.0ThrAsn: 0.0 ± 0.0
1.285ThrPro: 1.285 ± 0.68
1.285ThrGln: 1.285 ± 1.791
0.0ThrArg: 0.0 ± 0.0
5.141ThrSer: 5.141 ± 3.672
2.571ThrThr: 2.571 ± 1.359
2.571ThrVal: 2.571 ± 1.359
2.571ThrTrp: 2.571 ± 1.359
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.285ValAla: 1.285 ± 0.68
3.856ValCys: 3.856 ± 1.84
1.285ValAsp: 1.285 ± 0.68
0.0ValGlu: 0.0 ± 0.0
0.0ValPhe: 0.0 ± 0.0
3.856ValGly: 3.856 ± 2.884
0.0ValHis: 0.0 ± 0.0
1.285ValIle: 1.285 ± 2.249
2.571ValLys: 2.571 ± 1.359
1.285ValLeu: 1.285 ± 2.249
0.0ValMet: 0.0 ± 0.0
0.0ValAsn: 0.0 ± 0.0
5.141ValPro: 5.141 ± 1.669
1.285ValGln: 1.285 ± 0.68
2.571ValArg: 2.571 ± 1.359
1.285ValSer: 1.285 ± 0.68
2.571ValThr: 2.571 ± 1.939
2.571ValVal: 2.571 ± 1.939
3.856ValTrp: 3.856 ± 1.245
2.571ValTyr: 2.571 ± 1.359
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.285TrpCys: 1.285 ± 1.791
0.0TrpAsp: 0.0 ± 0.0
5.141TrpGlu: 5.141 ± 1.874
5.141TrpPhe: 5.141 ± 2.719
3.856TrpGly: 3.856 ± 2.039
0.0TrpHis: 0.0 ± 0.0
1.285TrpIle: 1.285 ± 0.68
2.571TrpLys: 2.571 ± 2.999
1.285TrpLeu: 1.285 ± 0.68
1.285TrpMet: 1.285 ± 0.68
1.285TrpAsn: 1.285 ± 0.68
2.571TrpPro: 2.571 ± 2.557
0.0TrpGln: 0.0 ± 0.0
5.141TrpArg: 5.141 ± 2.719
1.285TrpSer: 1.285 ± 0.68
1.285TrpThr: 1.285 ± 0.68
3.856TrpVal: 3.856 ± 2.039
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.285TyrAla: 1.285 ± 0.68
3.856TyrCys: 3.856 ± 1.245
3.856TyrAsp: 3.856 ± 1.84
0.0TyrGlu: 0.0 ± 0.0
1.285TyrPhe: 1.285 ± 0.68
2.571TyrGly: 2.571 ± 1.359
0.0TyrHis: 0.0 ± 0.0
2.571TyrIle: 2.571 ± 1.359
5.141TyrLys: 5.141 ± 1.983
5.141TyrLeu: 5.141 ± 2.074
0.0TyrMet: 0.0 ± 0.0
2.571TyrAsn: 2.571 ± 1.359
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
6.427TyrArg: 6.427 ± 1.264
1.285TyrSer: 1.285 ± 1.791
0.0TyrThr: 0.0 ± 0.0
2.571TyrVal: 2.571 ± 1.359
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (779 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski