Amino acid dipepetide frequency for Anaerotruncus colihominis DSM 17241

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.615AlaAla: 13.615 ± 0.189	1.805AlaCys: 1.805 ± 0.044	5.573AlaAsp: 5.573 ± 0.078	5.521AlaGlu: 5.521 ± 0.082	3.836AlaPhe: 3.836 ± 0.065	8.394AlaGly: 8.394 ± 0.102	1.701AlaHis: 1.701 ± 0.039	5.357AlaIle: 5.357 ± 0.073	4.123AlaLys: 4.123 ± 0.072	10.073AlaLeu: 10.073 ± 0.121	2.73AlaMet: 2.73 ± 0.054	2.608AlaAsn: 2.608 ± 0.051	3.965AlaPro: 3.965 ± 0.073	4.025AlaGln: 4.025 ± 0.074	5.914AlaArg: 5.914 ± 0.095	4.957AlaSer: 4.957 ± 0.077	3.39AlaThr: 3.39 ± 0.073	8.258AlaVal: 8.258 ± 0.101	0.83AlaTrp: 0.83 ± 0.03	2.906AlaTyr: 2.906 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	1.893CysAla: 1.893 ± 0.047	0.378CysCys: 0.378 ± 0.017	1.023CysAsp: 1.023 ± 0.03	0.99CysGlu: 0.99 ± 0.029	0.723CysPhe: 0.723 ± 0.028	1.98CysGly: 1.98 ± 0.049	0.27CysHis: 0.27 ± 0.013	1.024CysIle: 1.024 ± 0.027	0.746CysLys: 0.746 ± 0.025	1.277CysLeu: 1.277 ± 0.037	0.469CysMet: 0.469 ± 0.022	0.53CysAsn: 0.53 ± 0.021	0.809CysPro: 0.809 ± 0.027	0.423CysGln: 0.423 ± 0.019	1.055CysArg: 1.055 ± 0.029	0.876CysSer: 0.876 ± 0.022	0.876CysThr: 0.876 ± 0.029	1.181CysVal: 1.181 ± 0.031	0.173CysTrp: 0.173 ± 0.013	0.553CysTyr: 0.553 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	5.605AspAla: 5.605 ± 0.087	0.985AspCys: 0.985 ± 0.033	3.078AspAsp: 3.078 ± 0.076	4.419AspGlu: 4.419 ± 0.072	2.486AspPhe: 2.486 ± 0.052	5.117AspGly: 5.117 ± 0.068	0.929AspHis: 0.929 ± 0.032	3.7AspIle: 3.7 ± 0.062	2.385AspLys: 2.385 ± 0.051	4.816AspLeu: 4.816 ± 0.072	1.664AspMet: 1.664 ± 0.046	1.685AspAsn: 1.685 ± 0.037	2.4AspPro: 2.4 ± 0.052	1.505AspGln: 1.505 ± 0.036	3.063AspArg: 3.063 ± 0.052	2.889AspSer: 2.889 ± 0.053	2.983AspThr: 2.983 ± 0.056	3.647AspVal: 3.647 ± 0.065	0.669AspTrp: 0.669 ± 0.02	2.206AspTyr: 2.206 ± 0.05	0.0AspXaa: 0.0 ± 0.0
Glu	5.621GluAla: 5.621 ± 0.083	0.727GluCys: 0.727 ± 0.022	3.267GluAsp: 3.267 ± 0.067	4.144GluGlu: 4.144 ± 0.084	1.838GluPhe: 1.838 ± 0.046	3.945GluGly: 3.945 ± 0.07	1.301GluHis: 1.301 ± 0.033	4.418GluIle: 4.418 ± 0.072	4.111GluLys: 4.111 ± 0.073	6.348GluLeu: 6.348 ± 0.094	1.922GluMet: 1.922 ± 0.042	2.878GluAsn: 2.878 ± 0.053	2.357GluPro: 2.357 ± 0.048	3.534GluGln: 3.534 ± 0.061	4.31GluArg: 4.31 ± 0.068	3.064GluSer: 3.064 ± 0.056	3.428GluThr: 3.428 ± 0.063	3.509GluVal: 3.509 ± 0.067	0.584GluTrp: 0.584 ± 0.026	2.2GluTyr: 2.2 ± 0.045	0.0GluXaa: 0.0 ± 0.0
Phe	3.665PheAla: 3.665 ± 0.058	0.931PheCys: 0.931 ± 0.027	2.673PheAsp: 2.673 ± 0.058	2.444PheGlu: 2.444 ± 0.048	1.911PhePhe: 1.911 ± 0.051	3.32PheGly: 3.32 ± 0.05	0.755PheHis: 0.755 ± 0.024	2.414PheIle: 2.414 ± 0.055	1.486PheLys: 1.486 ± 0.035	3.696PheLeu: 3.696 ± 0.065	1.132PheMet: 1.132 ± 0.035	1.292PheAsn: 1.292 ± 0.038	1.525PhePro: 1.525 ± 0.041	1.227PheGln: 1.227 ± 0.035	1.785PheArg: 1.785 ± 0.039	3.03PheSer: 3.03 ± 0.051	2.402PheThr: 2.402 ± 0.048	2.681PheVal: 2.681 ± 0.053	0.44PheTrp: 0.44 ± 0.02	1.493PheTyr: 1.493 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	7.47GlyAla: 7.47 ± 0.105	1.535GlyCys: 1.535 ± 0.04	3.998GlyAsp: 3.998 ± 0.063	4.813GlyGlu: 4.813 ± 0.077	3.222GlyPhe: 3.222 ± 0.055	6.481GlyGly: 6.481 ± 0.084	1.326GlyHis: 1.326 ± 0.031	5.037GlyIle: 5.037 ± 0.072	4.279GlyLys: 4.279 ± 0.077	6.875GlyLeu: 6.875 ± 0.085	2.7GlyMet: 2.7 ± 0.052	2.51GlyAsn: 2.51 ± 0.05	1.958GlyPro: 1.958 ± 0.062	2.648GlyGln: 2.648 ± 0.046	4.824GlyArg: 4.824 ± 0.074	4.152GlySer: 4.152 ± 0.063	4.087GlyThr: 4.087 ± 0.066	6.262GlyVal: 6.262 ± 0.083	0.924GlyTrp: 0.924 ± 0.033	2.889GlyTyr: 2.889 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	1.561HisAla: 1.561 ± 0.037	0.358HisCys: 0.358 ± 0.017	0.916HisAsp: 0.916 ± 0.026	0.967HisGlu: 0.967 ± 0.029	0.804HisPhe: 0.804 ± 0.026	1.451HisGly: 1.451 ± 0.033	0.338HisHis: 0.338 ± 0.02	1.256HisIle: 1.256 ± 0.033	0.714HisLys: 0.714 ± 0.026	1.55HisLeu: 1.55 ± 0.04	0.484HisMet: 0.484 ± 0.019	0.682HisAsn: 0.682 ± 0.025	1.075HisPro: 1.075 ± 0.037	0.52HisGln: 0.52 ± 0.019	1.033HisArg: 1.033 ± 0.032	1.014HisSer: 1.014 ± 0.028	1.045HisThr: 1.045 ± 0.032	1.133HisVal: 1.133 ± 0.034	0.181HisTrp: 0.181 ± 0.013	0.64HisTyr: 0.64 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.073IleAla: 6.073 ± 0.069	1.187IleCys: 1.187 ± 0.028	3.884IleAsp: 3.884 ± 0.066	3.812IleGlu: 3.812 ± 0.054	2.467IlePhe: 2.467 ± 0.056	4.934IleGly: 4.934 ± 0.077	1.118IleHis: 1.118 ± 0.034	3.718IleIle: 3.718 ± 0.072	2.785IleLys: 2.785 ± 0.062	5.724IleLeu: 5.724 ± 0.091	1.625IleMet: 1.625 ± 0.043	2.171IleAsn: 2.171 ± 0.043	2.972IlePro: 2.972 ± 0.045	1.88IleGln: 1.88 ± 0.039	3.595IleArg: 3.595 ± 0.056	4.061IleSer: 4.061 ± 0.064	3.378IleThr: 3.378 ± 0.052	4.515IleVal: 4.515 ± 0.081	0.555IleTrp: 0.555 ± 0.024	1.953IleTyr: 1.953 ± 0.043	0.0IleXaa: 0.0 ± 0.0
Lys	4.46LysAla: 4.46 ± 0.077	0.582LysCys: 0.582 ± 0.026	2.299LysAsp: 2.299 ± 0.054	3.196LysGlu: 3.196 ± 0.068	1.363LysPhe: 1.363 ± 0.031	3.095LysGly: 3.095 ± 0.057	0.794LysHis: 0.794 ± 0.026	3.222LysIle: 3.222 ± 0.062	3.417LysLys: 3.417 ± 0.067	4.382LysLeu: 4.382 ± 0.065	1.495LysMet: 1.495 ± 0.038	2.149LysAsn: 2.149 ± 0.045	2.04LysPro: 2.04 ± 0.047	1.951LysGln: 1.951 ± 0.038	3.079LysArg: 3.079 ± 0.057	2.649LysSer: 2.649 ± 0.052	2.904LysThr: 2.904 ± 0.052	2.675LysVal: 2.675 ± 0.057	0.46LysTrp: 0.46 ± 0.021	1.6LysTyr: 1.6 ± 0.04	0.0LysXaa: 0.0 ± 0.0
Leu	9.131LeuAla: 9.131 ± 0.124	2.043LeuCys: 2.043 ± 0.047	5.521LeuAsp: 5.521 ± 0.069	6.129LeuGlu: 6.129 ± 0.077	4.176LeuPhe: 4.176 ± 0.067	6.372LeuGly: 6.372 ± 0.082	1.741LeuHis: 1.741 ± 0.04	5.541LeuIle: 5.541 ± 0.092	4.318LeuLys: 4.318 ± 0.064	9.666LeuLeu: 9.666 ± 0.125	2.691LeuMet: 2.691 ± 0.05	3.022LeuAsn: 3.022 ± 0.046	4.459LeuPro: 4.459 ± 0.068	2.652LeuGln: 2.652 ± 0.052	5.725LeuArg: 5.725 ± 0.072	6.642LeuSer: 6.642 ± 0.082	5.479LeuThr: 5.479 ± 0.066	5.485LeuVal: 5.485 ± 0.081	0.843LeuTrp: 0.843 ± 0.027	3.234LeuTyr: 3.234 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	2.769MetAla: 2.769 ± 0.053	0.368MetCys: 0.368 ± 0.02	1.765MetAsp: 1.765 ± 0.042	2.085MetGlu: 2.085 ± 0.041	0.946MetPhe: 0.946 ± 0.027	2.188MetGly: 2.188 ± 0.053	0.451MetHis: 0.451 ± 0.021	1.821MetIle: 1.821 ± 0.041	1.773MetLys: 1.773 ± 0.046	2.841MetLeu: 2.841 ± 0.051	0.927MetMet: 0.927 ± 0.027	1.19MetAsn: 1.19 ± 0.037	1.341MetPro: 1.341 ± 0.035	1.173MetGln: 1.173 ± 0.032	1.765MetArg: 1.765 ± 0.042	1.577MetSer: 1.577 ± 0.039	1.728MetThr: 1.728 ± 0.041	1.72MetVal: 1.72 ± 0.041	0.186MetTrp: 0.186 ± 0.012	0.674MetTyr: 0.674 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	3.146AsnAla: 3.146 ± 0.056	0.547AsnCys: 0.547 ± 0.023	1.742AsnAsp: 1.742 ± 0.039	1.989AsnGlu: 1.989 ± 0.051	1.308AsnPhe: 1.308 ± 0.035	2.968AsnGly: 2.968 ± 0.052	0.574AsnHis: 0.574 ± 0.023	2.438AsnIle: 2.438 ± 0.051	1.44AsnLys: 1.44 ± 0.038	3.102AsnLeu: 3.102 ± 0.053	1.025AsnMet: 1.025 ± 0.03	1.244AsnAsn: 1.244 ± 0.036	1.939AsnPro: 1.939 ± 0.039	1.16AsnGln: 1.16 ± 0.035	2.082AsnArg: 2.082 ± 0.049	1.768AsnSer: 1.768 ± 0.044	1.87AsnThr: 1.87 ± 0.044	2.094AsnVal: 2.094 ± 0.044	0.39AsnTrp: 0.39 ± 0.02	1.198AsnTyr: 1.198 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	4.531ProAla: 4.531 ± 0.071	0.589ProCys: 0.589 ± 0.024	3.124ProAsp: 3.124 ± 0.056	3.4ProGlu: 3.4 ± 0.065	1.789ProPhe: 1.789 ± 0.043	3.138ProGly: 3.138 ± 0.054	0.776ProHis: 0.776 ± 0.024	2.154ProIle: 2.154 ± 0.046	1.781ProLys: 1.781 ± 0.038	3.632ProLeu: 3.632 ± 0.063	1.024ProMet: 1.024 ± 0.029	1.254ProAsn: 1.254 ± 0.036	1.752ProPro: 1.752 ± 0.049	1.658ProGln: 1.658 ± 0.042	1.934ProArg: 1.934 ± 0.04	2.279ProSer: 2.279 ± 0.045	1.924ProThr: 1.924 ± 0.045	3.701ProVal: 3.701 ± 0.065	0.371ProTrp: 0.371 ± 0.021	1.488ProTyr: 1.488 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	3.809GlnAla: 3.809 ± 0.075	0.374GlnCys: 0.374 ± 0.018	1.497GlnAsp: 1.497 ± 0.041	2.329GlnGlu: 2.329 ± 0.048	1.27GlnPhe: 1.27 ± 0.032	2.221GlnGly: 2.221 ± 0.052	0.539GlnHis: 0.539 ± 0.022	2.449GlnIle: 2.449 ± 0.043	2.19GlnLys: 2.19 ± 0.047	3.122GlnLeu: 3.122 ± 0.052	1.254GlnMet: 1.254 ± 0.032	1.515GlnAsn: 1.515 ± 0.037	1.508GlnPro: 1.508 ± 0.038	1.528GlnGln: 1.528 ± 0.047	2.106GlnArg: 2.106 ± 0.045	1.917GlnSer: 1.917 ± 0.042	2.113GlnThr: 2.113 ± 0.044	2.12GlnVal: 2.12 ± 0.043	0.344GlnTrp: 0.344 ± 0.018	1.244GlnTyr: 1.244 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	5.731ArgAla: 5.731 ± 0.092	0.992ArgCys: 0.992 ± 0.03	3.093ArgAsp: 3.093 ± 0.056	4.178ArgGlu: 4.178 ± 0.07	2.523ArgPhe: 2.523 ± 0.048	4.06ArgGly: 4.06 ± 0.065	1.111ArgHis: 1.111 ± 0.032	3.806ArgIle: 3.806 ± 0.059	2.611ArgLys: 2.611 ± 0.052	6.201ArgLeu: 6.201 ± 0.097	1.949ArgMet: 1.949 ± 0.046	1.657ArgAsn: 1.657 ± 0.038	2.414ArgPro: 2.414 ± 0.058	2.328ArgGln: 2.328 ± 0.054	4.584ArgArg: 4.584 ± 0.079	2.927ArgSer: 2.927 ± 0.051	2.85ArgThr: 2.85 ± 0.053	3.789ArgVal: 3.789 ± 0.067	0.612ArgTrp: 0.612 ± 0.023	2.161ArgTyr: 2.161 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	5.508SerAla: 5.508 ± 0.076	0.881SerCys: 0.881 ± 0.031	3.25SerAsp: 3.25 ± 0.053	3.284SerGlu: 3.284 ± 0.059	2.579SerPhe: 2.579 ± 0.051	5.545SerGly: 5.545 ± 0.08	0.983SerHis: 0.983 ± 0.03	3.589SerIle: 3.589 ± 0.068	2.397SerLys: 2.397 ± 0.048	5.292SerLeu: 5.292 ± 0.081	1.649SerMet: 1.649 ± 0.036	1.773SerAsn: 1.773 ± 0.041	2.266SerPro: 2.266 ± 0.046	1.824SerGln: 1.824 ± 0.041	3.123SerArg: 3.123 ± 0.054	3.357SerSer: 3.357 ± 0.078	2.722SerThr: 2.722 ± 0.05	4.325SerVal: 4.325 ± 0.06	0.536SerTrp: 0.536 ± 0.023	1.861SerTyr: 1.861 ± 0.046	0.0SerXaa: 0.0 ± 0.0
Thr	5.628ThrAla: 5.628 ± 0.078	0.676ThrCys: 0.676 ± 0.023	2.935ThrAsp: 2.935 ± 0.05	2.881ThrGlu: 2.881 ± 0.056	2.041ThrPhe: 2.041 ± 0.041	4.793ThrGly: 4.793 ± 0.07	0.96ThrHis: 0.96 ± 0.029	3.239ThrIle: 3.239 ± 0.055	2.027ThrLys: 2.027 ± 0.048	5.263ThrLeu: 5.263 ± 0.077	1.341ThrMet: 1.341 ± 0.035	1.655ThrAsn: 1.655 ± 0.042	2.85ThrPro: 2.85 ± 0.056	1.698ThrGln: 1.698 ± 0.038	2.619ThrArg: 2.619 ± 0.052	2.548ThrSer: 2.548 ± 0.054	2.532ThrThr: 2.532 ± 0.052	4.504ThrVal: 4.504 ± 0.064	0.407ThrTrp: 0.407 ± 0.02	1.647ThrTyr: 1.647 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	5.637ValAla: 5.637 ± 0.073	1.507ValCys: 1.507 ± 0.034	3.812ValAsp: 3.812 ± 0.059	4.086ValGlu: 4.086 ± 0.066	3.069ValPhe: 3.069 ± 0.059	4.611ValGly: 4.611 ± 0.07	1.147ValHis: 1.147 ± 0.03	4.476ValIle: 4.476 ± 0.065	3.266ValLys: 3.266 ± 0.056	6.848ValLeu: 6.848 ± 0.076	2.039ValMet: 2.039 ± 0.046	2.406ValAsn: 2.406 ± 0.052	2.929ValPro: 2.929 ± 0.056	2.171ValGln: 2.171 ± 0.04	4.22ValArg: 4.22 ± 0.069	4.62ValSer: 4.62 ± 0.069	3.983ValThr: 3.983 ± 0.066	4.959ValVal: 4.959 ± 0.079	0.735ValTrp: 0.735 ± 0.026	2.424ValTyr: 2.424 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	0.745TrpAla: 0.745 ± 0.028	0.182TrpCys: 0.182 ± 0.013	0.557TrpAsp: 0.557 ± 0.025	0.646TrpGlu: 0.646 ± 0.025	0.43TrpPhe: 0.43 ± 0.018	0.692TrpGly: 0.692 ± 0.025	0.199TrpHis: 0.199 ± 0.014	0.556TrpIle: 0.556 ± 0.023	0.479TrpLys: 0.479 ± 0.021	1.073TrpLeu: 1.073 ± 0.035	0.315TrpMet: 0.315 ± 0.016	0.424TrpAsn: 0.424 ± 0.023	0.294TrpPro: 0.294 ± 0.018	0.39TrpGln: 0.39 ± 0.02	0.634TrpArg: 0.634 ± 0.026	0.527TrpSer: 0.527 ± 0.025	0.474TrpThr: 0.474 ± 0.022	0.529TrpVal: 0.529 ± 0.024	0.142TrpTrp: 0.142 ± 0.012	0.4TrpTyr: 0.4 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.985TyrAla: 2.985 ± 0.063	0.602TyrCys: 0.602 ± 0.021	2.229TyrAsp: 2.229 ± 0.042	2.192TyrGlu: 2.192 ± 0.049	1.523TyrPhe: 1.523 ± 0.037	2.683TyrGly: 2.683 ± 0.05	0.708TyrHis: 0.708 ± 0.025	2.188TyrIle: 2.188 ± 0.05	1.485TyrLys: 1.485 ± 0.036	3.088TyrLeu: 3.088 ± 0.065	0.85TyrMet: 0.85 ± 0.029	1.379TyrAsn: 1.379 ± 0.033	1.444TyrPro: 1.444 ± 0.035	1.156TyrGln: 1.156 ± 0.037	2.127TyrArg: 2.127 ± 0.048	1.888TyrSer: 1.888 ± 0.046	2.077TyrThr: 2.077 ± 0.047	1.861TyrVal: 1.861 ± 0.041	0.306TyrTrp: 0.306 ± 0.016	1.304TyrTyr: 1.304 ± 0.039	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4421 proteins (1126561 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---